SIMILAR PATTERNS OF AMINO ACIDS FOR 3Q1E_C_T44C128

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwc GLUTATHIONE
S-TRANSFERASE TSI-1

(Aegilops
tauschii) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  30
LEU A  25
LEU A  87
LEU A  73
 None
 0.97A 3q1eA-1gwcA:
0.0
3q1eC-1gwcA:
undetectable		 3q1eA-1gwcA:
20.52
3q1eC-1gwcA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT I

(Salmonella
enterica) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 LEU A 129
LEU A  84
LEU A 177
LEU A  59
 None
 1.00A 3q1eA-1i1qA:
0.0
3q1eC-1i1qA:
0.1		 3q1eA-1i1qA:
11.52
3q1eC-1i1qA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT I

(Salmonella
enterica) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 LEU A 177
LEU A  59
LEU A 129
LEU A  84
 None
 1.08A 3q1eA-1i1qA:
0.0
3q1eC-1i1qA:
0.1		 3q1eA-1i1qA:
11.52
3q1eC-1i1qA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh9 ACETYLGLUTAMATE
KINASE

(Escherichia
coli) 		PF00696
(AA_kinase) 		4 LEU A  38
PRO A 143
LEU A 168
LEU A 172
 None
 0.99A 3q1eA-1oh9A:
0.0
3q1eC-1oh9A:
0.0		 3q1eA-1oh9A:
14.83
3q1eC-1oh9A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh9 ACETYLGLUTAMATE
KINASE

(Escherichia
coli) 		PF00696
(AA_kinase) 		4 LEU A 168
LEU A 172
LEU A  38
PRO A 143
 None
 1.08A 3q1eA-1oh9A:
0.0
3q1eC-1oh9A:
0.0		 3q1eA-1oh9A:
14.83
3q1eC-1oh9A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjm IMPORTIN ALPHA-2
SUBUNIT

(Mus musculus) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 LEU B 256
LEU B 259
LEU B 301
LEU B 268
 None
 1.02A 3q1eA-1pjmB:
undetectable
3q1eC-1pjmB:
undetectable		 3q1eA-1pjmB:
14.95
3q1eC-1pjmB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjm IMPORTIN ALPHA-2
SUBUNIT

(Mus musculus) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 LEU B 301
LEU B 268
LEU B 256
LEU B 259
 None
 1.01A 3q1eA-1pjmB:
undetectable
3q1eC-1pjmB:
undetectable		 3q1eA-1pjmB:
14.95
3q1eC-1pjmB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgy BETA-LACTAMASE

(Citrobacter
freundii) 		PF00144
(Beta-lactamase) 		4 LEU A  73
LEU A 184
PRO A 181
LEU A 179
 None
 0.84A 3q1eA-1rgyA:
0.0
3q1eC-1rgyA:
0.0		 3q1eA-1rgyA:
14.29
3q1eC-1rgyA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u1h 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Arabidopsis
thaliana) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 LEU A 177
LEU A 180
PRO A 122
LEU A  75
 None
 1.04A 3q1eA-1u1hA:
0.0
3q1eC-1u1hA:
0.0		 3q1eA-1u1hA:
11.07
3q1eC-1u1hA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ujn DEHYDROQUINATE
SYNTHASE

(Thermus
thermophilus) 		PF01761
(DHQ_synthase) 		4 LEU A 277
LEU A 341
PRO A 283
LEU A 344
 None
 1.09A 3q1eA-1ujnA:
0.0
3q1eC-1ujnA:
0.0		 3q1eA-1ujnA:
15.80
3q1eC-1ujnA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ujn DEHYDROQUINATE
SYNTHASE

(Thermus
thermophilus) 		PF01761
(DHQ_synthase) 		4 LEU A 341
PRO A 283
LEU A 344
LEU A 277
 None
 1.10A 3q1eA-1ujnA:
0.0
3q1eC-1ujnA:
0.0		 3q1eA-1ujnA:
15.80
3q1eC-1ujnA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0a HYPOTHETICAL PROTEIN
MJ0783

(Methanocaldococcus
jannaschii) 		PF04199
(Cyclase) 		4 LEU A 185
LEU A   3
LEU A  88
LEU A 154
 None
 1.07A 3q1eA-2b0aA:
0.0
3q1eC-2b0aA:
0.0		 3q1eA-2b0aA:
18.18
3q1eC-2b0aA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfu PROBABLE
2-HYDROXYHEPTA-2,4-D
IENE-1,7-DIOATE
ISOMERASE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A   4
PRO A  44
LEU A 252
PRO A  92
 None
 1.12A 3q1eA-2dfuA:
2.0
3q1eC-2dfuA:
0.0		 3q1eA-2dfuA:
16.67
3q1eC-2dfuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfu PROBABLE
2-HYDROXYHEPTA-2,4-D
IENE-1,7-DIOATE
ISOMERASE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A 252
PRO A  92
LEU A   4
PRO A  44
 None
 1.08A 3q1eA-2dfuA:
2.0
3q1eC-2dfuA:
0.0		 3q1eA-2dfuA:
16.67
3q1eC-2dfuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
baylyi) 		PF03466
(LysR_substrate) 		4 LEU A 184
PRO A 218
LEU A 187
LEU A 194
 None
 0.62A 3q1eA-2f6gA:
0.0
3q1eC-2f6gA:
0.0		 3q1eA-2f6gA:
19.27
3q1eC-2f6gA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
baylyi) 		PF03466
(LysR_substrate) 		4 LEU A 194
LEU A 184
PRO A 218
LEU A 187
 None
 0.73A 3q1eA-2f6gA:
0.0
3q1eC-2f6gA:
0.0		 3q1eA-2f6gA:
19.27
3q1eC-2f6gA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jan TYROSYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00579
(tRNA-synt_1b) 		4 LEU A 275
LEU A 269
LEU A 307
LEU A 304
 None
 0.80A 3q1eA-2janA:
undetectable
3q1eC-2janA:
undetectable		 3q1eA-2janA:
14.66
3q1eC-2janA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jan TYROSYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00579
(tRNA-synt_1b) 		4 LEU A 307
LEU A 304
LEU A 275
LEU A 269
 None
 0.81A 3q1eA-2janA:
undetectable
3q1eC-2janA:
undetectable		 3q1eA-2janA:
14.66
3q1eC-2janA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0t PUTATIVE
GAMMA-CARBOXYMUCONOL
ACTONE DECARBOXYLASE
SUBUNIT

(Paraburkholderia
xenovorans) 		PF02627
(CMD) 		4 LEU A 162
PRO A 164
PRO A 132
LEU A 134
 None
 1.11A 3q1eA-2q0tA:
undetectable
3q1eC-2q0tA:
undetectable		 3q1eA-2q0tA:
18.97
3q1eC-2q0tA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qi9 VITAMIN B12 IMPORT
SYSTEM PERMEASE
PROTEIN BTUC

(Escherichia
coli) 		PF01032
(FecCD) 		4 LEU A  64
LEU A 288
LEU A  19
LEU A  22
 None
 0.99A 3q1eA-2qi9A:
undetectable
3q1eC-2qi9A:
undetectable		 3q1eA-2qi9A:
16.26
3q1eC-2qi9A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8b UNCHARACTERIZED
PROTEIN ATU2452

(Agrobacterium
fabrum) 		PF01738
(DLH) 		4 LEU A 212
PRO A 178
PRO A 172
LEU A 204
 None
 1.04A 3q1eA-2r8bA:
undetectable
3q1eC-2r8bA:
undetectable		 3q1eA-2r8bA:
19.68
3q1eC-2r8bA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8b UNCHARACTERIZED
PROTEIN ATU2452

(Agrobacterium
fabrum) 		PF01738
(DLH) 		4 PRO A 172
LEU A 204
LEU A 212
PRO A 178
 None
 0.93A 3q1eA-2r8bA:
undetectable
3q1eC-2r8bA:
undetectable		 3q1eA-2r8bA:
19.68
3q1eC-2r8bA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu0 PHYTASE

(Klebsiella
pneumoniae) 		PF00328
(His_Phos_2) 		4 LEU A 271
LEU A 267
LEU A 287
LEU A  22
 None
 1.00A 3q1eA-2wu0A:
undetectable
3q1eC-2wu0A:
undetectable		 3q1eA-2wu0A:
12.63
3q1eC-2wu0A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu0 PHYTASE

(Klebsiella
pneumoniae) 		PF00328
(His_Phos_2) 		4 LEU A 287
LEU A  22
LEU A 271
LEU A 267
 None
 1.12A 3q1eA-2wu0A:
undetectable
3q1eC-2wu0A:
undetectable		 3q1eA-2wu0A:
12.63
3q1eC-2wu0A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3v SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
HOMOLOG

(Danio rerio) 		PF16531
(SAS-6_N) 		4 LEU A 142
LEU A  60
LEU A 109
LEU A 123
 None
 1.05A 3q1eA-2y3vA:
undetectable
3q1eC-2y3vA:
undetectable		 3q1eA-2y3vA:
21.74
3q1eC-2y3vA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yys PROLINE
IMINOPEPTIDASE-RELAT
ED PROTEIN

(Thermus
thermophilus) 		PF12697
(Abhydrolase_6) 		4 LEU A 243
LEU A 221
LEU A 224
PRO A 127
 None
 1.10A 3q1eA-2yysA:
undetectable
3q1eC-2yysA:
undetectable		 3q1eA-2yysA:
14.49
3q1eC-2yysA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus) 		PF00148
(Oxidored_nitro) 		4 LEU A 297
PRO A 365
LEU A 367
LEU A 378
 None
 1.00A 3q1eA-3aeuA:
undetectable
3q1eC-3aeuA:
undetectable		 3q1eA-3aeuA:
15.44
3q1eC-3aeuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus) 		PF00148
(Oxidored_nitro) 		4 LEU A 378
LEU A 297
PRO A 365
LEU A 367
 None
 1.01A 3q1eA-3aeuA:
undetectable
3q1eC-3aeuA:
undetectable		 3q1eA-3aeuA:
15.44
3q1eC-3aeuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3azq AMINOPEPTIDASE

(Streptomyces
morookaense) 		PF00326
(Peptidase_S9) 		4 LEU A 306
PRO A 301
LEU A 267
LEU A 280
 None
 1.07A 3q1eA-3azqA:
undetectable
3q1eC-3azqA:
undetectable		 3q1eA-3azqA:
11.18
3q1eC-3azqA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqy ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Shewanella
oneidensis) 		PF03702
(AnmK) 		4 LEU A 195
LEU A 271
LEU A 229
LEU A 225
 None
 0.93A 3q1eA-3cqyA:
undetectable
3q1eC-3cqyA:
undetectable		 3q1eA-3cqyA:
16.76
3q1eC-3cqyA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqy ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Shewanella
oneidensis) 		PF03702
(AnmK) 		4 LEU A 229
LEU A 225
LEU A 195
LEU A 271
 None
 0.84A 3q1eA-3cqyA:
undetectable
3q1eC-3cqyA:
undetectable		 3q1eA-3cqyA:
16.76
3q1eC-3cqyA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0x LIPASE-ESTERASE
RELATED PROTEIN

(Clostridium
acetobutylicum) 		PF12146
(Hydrolase_4) 		4 LEU A  26
LEU A  43
LEU A 227
LEU A  32
 None
 1.04A 3q1eA-3e0xA:
undetectable
3q1eC-3e0xA:
undetectable		 3q1eA-3e0xA:
16.81
3q1eC-3e0xA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 LEU A 289
PRO A 306
LEU A 293
LEU A 309
 None
 1.10A 3q1eA-3e7gA:
undetectable
3q1eC-3e7gA:
undetectable		 3q1eA-3e7gA:
13.74
3q1eC-3e7gA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvq FE(3+) IONS IMPORT
ATP-BINDING PROTEIN
FBPC

(Neisseria
gonorrhoeae) 		PF00005
(ABC_tran) 		4 LEU A  82
PRO A 157
LEU A 159
LEU A 162
 None
 0.85A 3q1eA-3fvqA:
undetectable
3q1eC-3fvqA:
undetectable		 3q1eA-3fvqA:
16.42
3q1eC-3fvqA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvq FE(3+) IONS IMPORT
ATP-BINDING PROTEIN
FBPC

(Neisseria
gonorrhoeae) 		PF00005
(ABC_tran) 		4 LEU A 162
LEU A  82
PRO A 157
LEU A 159
 None
 0.87A 3q1eA-3fvqA:
undetectable
3q1eC-3fvqA:
undetectable		 3q1eA-3fvqA:
16.42
3q1eC-3fvqA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glg DNA POLYMERASE III
SUBUNIT DELTA

(Escherichia
coli) 		PF06144
(DNA_pol3_delta)
PF14840
(DNA_pol3_delt_C) 		4 LEU A 257
LEU A 298
LEU A 327
LEU A 330
 None
 1.08A 3q1eA-3glgA:
undetectable
3q1eC-3glgA:
undetectable		 3q1eA-3glgA:
18.50
3q1eC-3glgA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3imh GALACTOSE-1-EPIMERAS
E

(Lactobacillus
acidophilus) 		PF01263
(Aldose_epim) 		4 LEU A 185
LEU A 255
LEU A 240
LEU A 273
 None
 1.07A 3q1eA-3imhA:
undetectable
3q1eC-3imhA:
undetectable		 3q1eA-3imhA:
14.54
3q1eC-3imhA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuz PUTATIVE GLYOXALASE
SUPERFAMILY PROTEIN

(Cupriavidus
pinatubonensis) 		PF07063
(DUF1338) 		4 PRO A 108
LEU A 106
LEU A 195
LEU A 199
 P6G  A 340 ( 4.8A)
None
None
None
 1.07A 3q1eA-3iuzA:
undetectable
3q1eC-3iuzA:
undetectable		 3q1eA-3iuzA:
19.16
3q1eC-3iuzA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzy INTERSECTIN 2

(Homo sapiens) 		PF00168
(C2) 		4 LEU A1608
LEU A1620
PRO A1586
LEU A1584
 None
 1.03A 3q1eA-3jzyA:
2.6
3q1eC-3jzyA:
3.0		 3q1eA-3jzyA:
10.78
3q1eC-3jzyA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzy INTERSECTIN 2

(Homo sapiens) 		PF00168
(C2) 		4 PRO A1586
LEU A1584
LEU A1608
LEU A1620
 None
 0.98A 3q1eA-3jzyA:
2.6
3q1eC-3jzyA:
3.0		 3q1eA-3jzyA:
10.78
3q1eC-3jzyA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
sp. ADP1) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 LEU A 184
PRO A 218
LEU A 187
LEU A 194
 None
 0.64A 3q1eA-3k1nA:
undetectable
3q1eC-3k1nA:
undetectable		 3q1eA-3k1nA:
16.11
3q1eC-3k1nA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
sp. ADP1) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 LEU A 194
LEU A 184
PRO A 218
LEU A 187
 None
 0.74A 3q1eA-3k1nA:
undetectable
3q1eC-3k1nA:
undetectable		 3q1eA-3k1nA:
16.11
3q1eC-3k1nA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l07 BIFUNCTIONAL PROTEIN
FOLD

(Francisella
tularensis) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 PRO A  32
LEU A  34
LEU A  17
LEU A 270
 None
 1.11A 3q1eA-3l07A:
undetectable
3q1eC-3l07A:
undetectable		 3q1eA-3l07A:
17.87
3q1eC-3l07A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN

(Pseudomonas
putida) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 LEU A  25
LEU A  20
LEU A 153
LEU A  66
 None
 0.98A 3q1eA-3lxzA:
undetectable
3q1eC-3lxzA:
undetectable		 3q1eA-3lxzA:
17.78
3q1eC-3lxzA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN

(Pseudomonas
putida) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 LEU A 153
LEU A  66
LEU A  25
LEU A  20
 None
 1.02A 3q1eA-3lxzA:
undetectable
3q1eC-3lxzA:
undetectable		 3q1eA-3lxzA:
17.78
3q1eC-3lxzA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 LEU A 160
LEU A 103
PRO A  94
LEU A 143
 None
 0.98A 3q1eA-3nnkA:
undetectable
3q1eC-3nnkA:
undetectable		 3q1eA-3nnkA:
14.32
3q1eC-3nnkA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pja TRANSLIN

(Homo sapiens) 		PF01997
(Translin) 		4 LEU A  39
LEU A 101
LEU A 151
LEU A 147
 None
 1.03A 3q1eA-3pjaA:
undetectable
3q1eC-3pjaA:
undetectable		 3q1eA-3pjaA:
21.68
3q1eC-3pjaA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pja TRANSLIN

(Homo sapiens) 		PF01997
(Translin) 		4 LEU A 151
LEU A 147
LEU A  39
LEU A 101
 None
 0.98A 3q1eA-3pjaA:
undetectable
3q1eC-3pjaA:
undetectable		 3q1eA-3pjaA:
21.68
3q1eC-3pjaA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2

(Sulfolobus
solfataricus) 		PF01905
(DevR) 		4 LEU A 183
PRO A 144
LEU A  15
LEU A  12
 None
 1.11A 3q1eA-3ps0A:
undetectable
3q1eC-3ps0A:
undetectable		 3q1eA-3ps0A:
15.51
3q1eC-3ps0A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbw ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Pseudomonas
aeruginosa) 		PF03702
(AnmK) 		4 LEU A 223
LEU A 219
LEU A 189
LEU A 265
 None
 0.80A 3q1eA-3qbwA:
undetectable
3q1eC-3qbwA:
undetectable		 3q1eA-3qbwA:
15.34
3q1eC-3qbwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpt TRANSCRIPTIONAL
REGULATOR SLYA

(Salmonella
enterica) 		PF01047
(MarR) 		4 LEU A  24
LEU A  27
LEU A  70
LEU A  75
 None
 0.98A 3q1eA-3qptA:
undetectable
3q1eC-3qptA:
undetectable		 3q1eA-3qptA:
20.67
3q1eC-3qptA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpt TRANSCRIPTIONAL
REGULATOR SLYA

(Salmonella
enterica) 		PF01047
(MarR) 		4 LEU A  70
LEU A  75
LEU A  24
LEU A  27
 None
 1.06A 3q1eA-3qptA:
undetectable
3q1eC-3qptA:
undetectable		 3q1eA-3qptA:
20.67
3q1eC-3qptA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT M
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N

(Escherichia
coli) 		no annotation 4 LEU M 147
PRO N 387
LEU M 186
LEU M 183
 None
 0.75A 3q1eA-3rkoM:
undetectable
3q1eC-3rkoM:
undetectable		 3q1eA-3rkoM:
11.39
3q1eC-3rkoM:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6k ACETYLGLUTAMATE
KINASE

(Xanthomonas
campestris) 		PF00696
(AA_kinase)
PF04768
(NAT) 		4 LEU A 277
LEU A 281
PRO A  74
LEU A  72
 None
 0.88A 3q1eA-3s6kA:
undetectable
3q1eC-3s6kA:
undetectable		 3q1eA-3s6kA:
14.25
3q1eC-3s6kA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdo NITRILOTRIACETATE
MONOOXYGENASE

(Burkholderia
pseudomallei) 		PF00296
(Bac_luciferase) 		4 LEU A 324
PRO A 319
LEU A 297
LEU A 300
 None
 1.08A 3q1eA-3sdoA:
undetectable
3q1eC-3sdoA:
undetectable		 3q1eA-3sdoA:
13.68
3q1eC-3sdoA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2c FRUCTOSE-1,6-BISPHOS
PHATE
ALDOLASE/PHOSPHATASE

(Pyrobaculum
neutrophilum) 		PF01950
(FBPase_3) 		4 LEU A 237
PRO A 235
PRO A 142
LEU A 273
 None
 1.00A 3q1eA-3t2cA:
undetectable
3q1eC-3t2cA:
undetectable		 3q1eA-3t2cA:
14.14
3q1eC-3t2cA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2c FRUCTOSE-1,6-BISPHOS
PHATE
ALDOLASE/PHOSPHATASE

(Pyrobaculum
neutrophilum) 		PF01950
(FBPase_3) 		4 PRO A 142
LEU A 273
LEU A 237
PRO A 235
 None
 0.91A 3q1eA-3t2cA:
undetectable
3q1eC-3t2cA:
undetectable		 3q1eA-3t2cA:
14.14
3q1eC-3t2cA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7b ACETYLGLUTAMATE
KINASE

(Yersinia pestis) 		PF00696
(AA_kinase) 		4 LEU A 167
LEU A 171
LEU A  37
PRO A 142
 None
 1.12A 3q1eA-3t7bA:
undetectable
3q1eC-3t7bA:
undetectable		 3q1eA-3t7bA:
17.37
3q1eC-3t7bA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrt BETA-LACTAMASE

(Chromohalobacter
sp. 560) 		PF00144
(Beta-lactamase) 		4 LEU A  77
LEU A  74
PRO A 182
LEU A 180
 None
 0.84A 3q1eA-3wrtA:
undetectable
3q1eC-3wrtA:
undetectable		 3q1eA-3wrtA:
17.45
3q1eC-3wrtA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrt BETA-LACTAMASE

(Chromohalobacter
sp. 560) 		PF00144
(Beta-lactamase) 		4 PRO A 182
LEU A 180
LEU A  77
LEU A  74
 None
 0.92A 3q1eA-3wrtA:
undetectable
3q1eC-3wrtA:
undetectable		 3q1eA-3wrtA:
17.45
3q1eC-3wrtA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq6 PUTATIVE ARSENICAL
PUMP-DRIVING ATPASE

(Methanothermobacter
thermautotrophicus) 		PF02374
(ArsA_ATPase) 		4 LEU A 131
LEU A 156
PRO A 159
LEU A 155
 None
 1.04A 3q1eA-3zq6A:
undetectable
3q1eC-3zq6A:
undetectable		 3q1eA-3zq6A:
16.36
3q1eC-3zq6A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h59 IRON-COMPOUND ABC
TRANSPORTER, IRON
COMPOUND-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01497
(Peripla_BP_2) 		4 LEU A 161
PRO A 317
LEU A 238
LEU A 235
 None
 0.92A 3q1eA-4h59A:
undetectable
3q1eC-4h59A:
undetectable		 3q1eA-4h59A:
15.64
3q1eC-4h59A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h59 IRON-COMPOUND ABC
TRANSPORTER, IRON
COMPOUND-BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF01497
(Peripla_BP_2) 		4 LEU A 238
LEU A 235
LEU A 161
PRO A 317
 None
 1.00A 3q1eA-4h59A:
undetectable
3q1eC-4h59A:
undetectable		 3q1eA-4h59A:
15.64
3q1eC-4h59A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcy THIAMINASE-I

(Naegleria
gruberi) 		no annotation 4 LEU A 117
LEU A 301
LEU A 292
LEU A 311
 None
 1.11A 3q1eA-4hcyA:
undetectable
3q1eC-4hcyA:
undetectable		 3q1eA-4hcyA:
15.38
3q1eC-4hcyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7m PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF13646
(HEAT_2) 		4 LEU A  57
LEU A  61
LEU A  77
LEU A  73
 None
 0.89A 3q1eA-4l7mA:
undetectable
3q1eC-4l7mA:
undetectable		 3q1eA-4l7mA:
17.56
3q1eC-4l7mA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7m PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF13646
(HEAT_2) 		4 LEU A  77
LEU A  73
LEU A  57
LEU A  61
 None
 0.86A 3q1eA-4l7mA:
undetectable
3q1eC-4l7mA:
undetectable		 3q1eA-4l7mA:
17.56
3q1eC-4l7mA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz0 GENOME POLYPROTEIN

(Cardiovirus A) 		PF00680
(RdRP_1) 		4 LEU A 186
LEU A 190
LEU A 273
LEU A 270
 None
 1.02A 3q1eA-4nz0A:
undetectable
3q1eC-4nz0A:
undetectable		 3q1eA-4nz0A:
12.89
3q1eC-4nz0A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qnx TRNA
(MO5U34)-METHYLTRANS
FERASE

(Escherichia
coli) 		PF08003
(Methyltransf_9) 		4 LEU A 227
PRO A 253
LEU A 318
LEU A 224
 None
 0.85A 3q1eA-4qnxA:
undetectable
3q1eC-4qnxA:
undetectable		 3q1eA-4qnxA:
18.04
3q1eC-4qnxA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qnx TRNA
(MO5U34)-METHYLTRANS
FERASE

(Escherichia
coli) 		PF08003
(Methyltransf_9) 		4 LEU A 318
LEU A 224
LEU A 227
PRO A 253
 None
 0.98A 3q1eA-4qnxA:
undetectable
3q1eC-4qnxA:
undetectable		 3q1eA-4qnxA:
18.04
3q1eC-4qnxA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0z ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE FICD

(Homo sapiens) 		PF02661
(Fic) 		4 LEU A 114
LEU A 110
LEU A 162
LEU A 143
 None
 0.98A 3q1eA-4u0zA:
undetectable
3q1eC-4u0zA:
undetectable		 3q1eA-4u0zA:
16.61
3q1eC-4u0zA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wky BETA-KETOACYL
SYNTHASE

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A 460
LEU A 496
LEU A 470
LEU A 473
 None
 1.04A 3q1eA-4wkyA:
undetectable
3q1eC-4wkyA:
undetectable		 3q1eA-4wkyA:
12.27
3q1eC-4wkyA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgt FRQ-INTERACTING RNA
HELICASE

(Neurospora
crassa) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		4 LEU A 952
LEU A 956
LEU A1067
LEU A 974
 None
 1.08A 3q1eA-4xgtA:
undetectable
3q1eC-4xgtA:
undetectable		 3q1eA-4xgtA:
7.97
3q1eC-4xgtA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4c UDP-2,3-DIACYLGLUCOS
AMINE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00149
(Metallophos) 		4 LEU A  96
LEU A  75
LEU A 112
LEU A  39
 None
 1.05A 3q1eA-5b4cA:
undetectable
3q1eC-5b4cA:
undetectable		 3q1eA-5b4cA:
18.10
3q1eC-5b4cA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4c UDP-2,3-DIACYLGLUCOS
AMINE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00149
(Metallophos) 		4 LEU A 112
LEU A  39
LEU A  96
LEU A  75
 None
 1.04A 3q1eA-5b4cA:
undetectable
3q1eC-5b4cA:
undetectable		 3q1eA-5b4cA:
18.10
3q1eC-5b4cA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cff STAUFEN

(Drosophila
melanogaster) 		PF16482
(Staufen_C) 		4 LEU E 961
LEU E 962
LEU E1012
LEU E1015
 None
 1.04A 3q1eA-5cffE:
undetectable
3q1eC-5cffE:
undetectable		 3q1eA-5cffE:
19.66
3q1eC-5cffE:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 LEU A 171
LEU A 174
LEU A 259
LEU A 178
 None
 0.93A 3q1eA-5df0A:
3.4
3q1eC-5df0A:
undetectable		 3q1eA-5df0A:
12.55
3q1eC-5df0A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 LEU A 259
LEU A 178
LEU A 171
LEU A 174
 None
 0.86A 3q1eA-5df0A:
3.4
3q1eC-5df0A:
undetectable		 3q1eA-5df0A:
12.55
3q1eC-5df0A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9p GALECTIN-3

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 LEU A 218
LEU A 219
LEU A 147
PRO A 161
 None
 1.04A 3q1eA-5h9pA:
undetectable
3q1eC-5h9pA:
undetectable		 3q1eA-5h9pA:
24.22
3q1eC-5h9pA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idn CYCLIN-DEPENDENT
KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 136
LEU A 132
LEU A 316
LEU A 312
 None
 1.04A 3q1eA-5idnA:
undetectable
3q1eC-5idnA:
undetectable		 3q1eA-5idnA:
17.19
3q1eC-5idnA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF12859
(ANAPC1) 		4 LEU A1618
LEU A1656
LEU A1634
LEU A1651
 None
 0.81A 3q1eA-5lcwA:
3.8
3q1eC-5lcwA:
undetectable		 3q1eA-5lcwA:
5.43
3q1eC-5lcwA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF12859
(ANAPC1) 		4 LEU A1634
LEU A1651
LEU A1618
LEU A1656
 None
 0.87A 3q1eA-5lcwA:
3.8
3q1eC-5lcwA:
undetectable		 3q1eA-5lcwA:
5.43
3q1eC-5lcwA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2y TSSK C

(Escherichia
coli) 		PF05936
(T6SS_VasE) 		4 LEU A 408
LEU A 410
LEU A 339
LEU A 419
 None
 1.05A 3q1eA-5m2yA:
undetectable
3q1eC-5m2yA:
undetectable		 3q1eA-5m2yA:
20.98
3q1eC-5m2yA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlg RENIN

(Rattus
norvegicus) 		no annotation 4 LEU A 255
LEU A 256
LEU A 341
LEU A 279
 None
 1.01A 3q1eA-5mlgA:
1.2
3q1eC-5mlgA:
1.1		 3q1eA-5mlgA:
27.43
3q1eC-5mlgA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlg RENIN

(Rattus
norvegicus) 		no annotation 4 LEU A 341
LEU A 279
LEU A 255
LEU A 256
 None
 1.03A 3q1eA-5mlgA:
1.2
3q1eC-5mlgA:
1.1		 3q1eA-5mlgA:
27.43
3q1eC-5mlgA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzy GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT A

(Myxococcus
xanthus) 		PF01144
(CoA_trans) 		4 LEU A  50
LEU A  22
LEU A 164
PRO A  33
 None
 0.84A 3q1eA-5mzyA:
undetectable
3q1eC-5mzyA:
undetectable		 3q1eA-5mzyA:
16.23
3q1eC-5mzyA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzy GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT A

(Myxococcus
xanthus) 		PF01144
(CoA_trans) 		4 LEU A 164
PRO A  33
LEU A  50
LEU A  22
 None
 0.82A 3q1eA-5mzyA:
undetectable
3q1eC-5mzyA:
undetectable		 3q1eA-5mzyA:
16.23
3q1eC-5mzyA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfb GALECTIN-3

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 LEU A 218
LEU A 219
LEU A 147
PRO A 161
 None
 1.04A 3q1eA-5nfbA:
undetectable
3q1eC-5nfbA:
undetectable		 3q1eA-5nfbA:
23.30
3q1eC-5nfbA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nr1 FTSZ-BINDING PROTEIN
FZLA

(Caulobacter
vibrioides) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 LEU A  28
LEU A  23
LEU A 167
LEU A  74
 None
 1.11A 3q1eA-5nr1A:
undetectable
3q1eC-5nr1A:
undetectable		 3q1eA-5nr1A:
18.42
3q1eC-5nr1A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umg DIHYDROPTEROATE
SYNTHASE

(Klebsiella
pneumoniae) 		PF00809
(Pterin_bind) 		4 LEU A   3
LEU A  12
LEU A 184
LEU A 214
 None
 1.10A 3q1eA-5umgA:
undetectable
3q1eC-5umgA:
undetectable		 3q1eA-5umgA:
20.77
3q1eC-5umgA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umg DIHYDROPTEROATE
SYNTHASE

(Klebsiella
pneumoniae) 		PF00809
(Pterin_bind) 		4 LEU A 184
LEU A 214
LEU A   3
LEU A  12
 None
 1.07A 3q1eA-5umgA:
undetectable
3q1eC-5umgA:
undetectable		 3q1eA-5umgA:
20.77
3q1eC-5umgA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyl INNER TEGUMENT
PROTEIN

(Human
alphaherpesvirus
1) 		PF03970
(Herpes_UL37_1) 		4 LEU A 551
LEU A 552
PRO A 101
LEU A 105
 None
 1.09A 3q1eA-5vylA:
undetectable
3q1eC-5vylA:
undetectable		 3q1eA-5vylA:
13.57
3q1eC-5vylA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6avy ACYL-PROTEIN
THIOESTERASE 2

(Zea mays) 		no annotation 4 LEU A 244
LEU A 221
PRO A 188
LEU A 190
 None
 0.95A 3q1eA-6avyA:
undetectable
3q1eC-6avyA:
undetectable		 3q1eA-6avyA:
24.37
3q1eC-6avyA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8

(Homo sapiens) 		no annotation 4 LEU E 508
LEU E 509
LEU E1117
LEU E 503
 None
 0.97A 3q1eA-6c3pE:
undetectable
3q1eC-6c3pE:
undetectable		 3q1eA-6c3pE:
21.19
3q1eC-6c3pE:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8

(Homo sapiens) 		no annotation 4 LEU E1117
LEU E 503
LEU E 508
LEU E 509
 None
 1.06A 3q1eA-6c3pE:
undetectable
3q1eC-6c3pE:
undetectable		 3q1eA-6c3pE:
21.19
3q1eC-6c3pE:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8l -

(-) 		no annotation 4 LEU G 343
LEU G 345
LEU G 365
LEU G 369
 None
 1.02A 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable		 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8l -

(-) 		no annotation 4 LEU G 365
LEU G 369
LEU G 343
LEU G 345
 None
 0.96A 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable		 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fof GALECTIN-3,GALECTIN-
3

(Homo sapiens) 		no annotation 4 LEU C 147
PRO C 161
LEU C 218
LEU C 219
 None
 1.11A 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable		 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fof GALECTIN-3,GALECTIN-
3

(Homo sapiens) 		no annotation 4 LEU C 218
LEU C 219
LEU C 147
PRO C 161
 None
 1.07A 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable		 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6grw -

(-) 		no annotation 4 LEU A  62
LEU A  65
PRO A  37
LEU A 332
 None
 0.89A 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable		 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6grw -

(-) 		no annotation 4 PRO A  37
LEU A 332
LEU A  62
LEU A  65
 None
 0.79A 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable		 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable