SIMILAR PATTERNS OF AMINO ACIDS FOR 3PRS_A_RITA1001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1axn | ANNEXIN III (Homo sapiens) |
PF00191(Annexin) | 5 | ILE A 145LEU A 100THR A 149ILE A 244THR A 122 | None | 1.00A | 3prsA-1axnA:undetectable | 3prsA-1axnA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1brw | PROTEIN (PYRIMIDINENUCLEOSIDEPHOSPHORYLASE) (Geobacillusstearothermophilus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 5 | ASP A 267ILE A 184ILE A 121THR A 90ILE A 150 | NoneNoneNone CA A3001 (-4.0A)None | 1.19A | 3prsA-1brwA:0.0 | 3prsA-1brwA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1feh | PROTEIN (PERIPLASMICHYDROGENASE 1) (Clostridiumpasteurianum) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C)PF12838(Fer4_7)PF13510(Fer2_4) | 5 | ILE A 268ASP A 267ALA A 230ILE A 198ILE A 522 | HC1 A 580 ( 4.8A)NoneHC1 A 580 (-3.1A)NoneNone | 1.16A | 3prsA-1fehA:undetectable | 3prsA-1fehA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gh6 | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF01857(RB_B)PF01858(RB_A) | 5 | ALA B 734ILE B 680LEU B 665ILE B 753THR B 738 | None | 1.09A | 3prsA-1gh6B:undetectable | 3prsA-1gh6B:19.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ibq | ASPERGILLOPEPSIN (Aspergillusphoenicis) |
PF00026(Asp) | 6 | ILE A 72TYR A 74LEU A 120THR A 130ILE A 212THR A 218 | None | 0.38A | 3prsA-1ibqA:49.0 | 3prsA-1ibqA:56.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ize | ASPARTIC PROTEINASE (Aspergillusoryzae) |
PF00026(Asp) | 7 | ILE A 73TYR A 75LEU A 121THR A 131ILE A 212THR A 218ILE A 293 | None | 0.43A | 3prsA-1izeA:49.9 | 3prsA-1izeA:58.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mk4 | HYPOTHETICAL PROTEINYQJY (Bacillussubtilis) |
PF00583(Acetyltransf_1) | 5 | ALA A 117ILE A 84THR A 53ILE A 70ILE A 93 | None | 1.19A | 3prsA-1mk4A:0.0 | 3prsA-1mk4A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ni3 | YCHF GTP-BINDINGPROTEIN (Schizosaccharomycespombe) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 5 | ALA A 125TYR A 229LEU A 144ILE A 25ILE A 297 | None | 1.08A | 3prsA-1ni3A:undetectable | 3prsA-1ni3A:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oa1 | HYDROXYLAMINEREDUCTASE (Desulfovibriovulgaris) |
PF03063(Prismane) | 5 | ALA A 73ILE A 84ILE A 152THR A 71ILE A 136 | NoneNoneNoneSF4 A1554 (-3.1A)None | 1.25A | 3prsA-1oa1A:0.0 | 3prsA-1oa1A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhg | ATP-DEPENDENTHELICASE PCRA (Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | ALA A 567ILE A 321LEU A 577ILE A 300ILE A 311 | None | 0.90A | 3prsA-1qhgA:undetectable | 3prsA-1qhgA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhh | PROTEIN (PCRA(SUBUNIT)) (Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | ALA D 567ILE B 321LEU D 577ILE B 300ILE B 311 | None | 0.97A | 3prsA-1qhhD:undetectable | 3prsA-1qhhD:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r0l | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Zymomonasmobilis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | ILE A 315LEU A 228THR A 273ILE A 102ILE A 208 | NoneNoneNoneNDP A 400 ( 4.9A)None | 1.22A | 3prsA-1r0lA:undetectable | 3prsA-1r0lA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umf | CHORISMATE SYNTHASE (Helicobacterpylori) |
PF01264(Chorismate_synt) | 5 | ILE A 83ASP A 61ALA A 130LEU A 10ILE A 206 | None | 1.14A | 3prsA-1umfA:undetectable | 3prsA-1umfA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us2 | ENDO-BETA-1,4-XYLANASE (Cellvibriojaponicus) |
PF00331(Glyco_hydro_10)PF03426(CBM_15) | 5 | ILE A 476ALA A 536LEU A 498THR A 293THR A 540 | None | 1.22A | 3prsA-1us2A:undetectable | 3prsA-1us2A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w3i | 2-KETO-3-DEOXYGLUCONATE ALDOLASE (Sulfolobussolfataricus) |
PF00701(DHDPS) | 5 | ALA A 135ILE A 9LEU A 242THR A 249ILE A 70 | NoneNoneGOL A1296 (-3.4A)NoneNone | 1.16A | 3prsA-1w3iA:undetectable | 3prsA-1w3iA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xtt | PROBABLE URACILPHOSPHORIBOSYLTRANSFERASE (Sulfolobussolfataricus) |
PF14681(UPRTase) | 5 | ILE A 75ALA A 139LEU A 32THR A 23ILE A 203 | NoneNoneNoneNoneU5P A1250 (-4.1A) | 1.22A | 3prsA-1xttA:undetectable | 3prsA-1xttA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y7m | HYPOTHETICAL PROTEINBSU14040 (Bacillussubtilis) |
PF01476(LysM)PF03734(YkuD) | 5 | ILE A 15ASP A 10ILE A 54LEU A 48ILE A 122 | None | 1.09A | 3prsA-1y7mA:undetectable | 3prsA-1y7mA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 5 | ILE A1156ALA A1153TYR A1080THR A1268ILE A1190 | None | 1.24A | 3prsA-2b39A:undetectable | 3prsA-2b39A:11.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5m | DAMAGE-SPECIFIC DNABINDING PROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | ALA A 154TYR A 84LEU A 135ILE A 79ILE A1068 | None | 1.11A | 3prsA-2b5mA:undetectable | 3prsA-2b5mA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 5 | ILE A 559ASP A 428LEU A 613ILE A 534ILE A 504 | None | 1.20A | 3prsA-2c3oA:undetectable | 3prsA-2c3oA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5i | AZO REDUCTASE (Escherichiacoli) |
PF02525(Flavodoxin_2) | 5 | ILE A 100ALA A 93LEU A 160ILE A 197THR A 138 | None | 1.21A | 3prsA-2d5iA:undetectable | 3prsA-2d5iA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7d | UVRABC SYSTEMPROTEIN B (Bacillussubtilis) |
PF00271(Helicase_C)PF02151(UVR)PF04851(ResIII)PF12344(UvrB) | 5 | ILE A 138ALA A 126LEU A 148THR A 314ILE A 179 | None | 1.07A | 3prsA-2d7dA:undetectable | 3prsA-2d7dA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e1m | L-GLUTAMATE OXIDASE (Streptomycessp. X-119-6) |
PF01593(Amino_oxidase) | 5 | ILE A 48ILE A 98LEU A 336ILE A 348ILE A 63 | NoneFAD A 801 (-4.8A)NoneNoneNone | 1.23A | 3prsA-2e1mA:undetectable | 3prsA-2e1mA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ece | 462AA LONGHYPOTHETICALSELENIUM-BINDINGPROTEIN (Sulfurisphaeratokodaii) |
PF05694(SBP56) | 5 | ILE A 60ALA A 46THR A 11ILE A 99ILE A 123 | None | 1.18A | 3prsA-2eceA:undetectable | 3prsA-2eceA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEALPHA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF01571(GCV_T)PF07992(Pyr_redox_2)PF08669(GCV_T_C)PF13510(Fer2_4) | 5 | ALA A 493THR A 367ILE A 256THR A 491ILE A 266 | None | 1.15A | 3prsA-2gahA:undetectable | 3prsA-2gahA:15.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i14 | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Pyrococcusfuriosus) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ILE A 153ILE A 12THR A 17ILE A 91ILE A 359 | None | 1.17A | 3prsA-2i14A:undetectable | 3prsA-2i14A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iaf | HYPOTHETICAL PROTEINSDHL (Legionellapneumophila) |
PF03315(SDH_beta) | 5 | ILE A 140ALA A 13LEU A 37ILE A 78ILE A 92 | None | 1.16A | 3prsA-2iafA:undetectable | 3prsA-2iafA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oaj | PROTEIN SNI1 (Saccharomycescerevisiae) |
PF08596(Lgl_C) | 5 | ILE A 357ALA A 332ILE A 408ILE A 368ILE A 287 | None | 1.25A | 3prsA-2oajA:undetectable | 3prsA-2oajA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjr | PROTEIN (HELICASEPCRA) (Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | ALA B 567ILE A 321LEU B 577ILE A 300ILE A 311 | None | 0.97A | 3prsA-2pjrB:undetectable | 3prsA-2pjrB:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ptg | ENOYL-ACYL CARRIERREDUCTASE (Eimeria tenella) |
PF13561(adh_short_C2) | 5 | ILE A 211ASP A 188ALA A 185ILE A 118ILE A 284 | None | 1.20A | 3prsA-2ptgA:undetectable | 3prsA-2ptgA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qne | PUTATIVEMETHYLTRANSFERASE (Desulfitobacteriumhafniense) |
PF06253(MTTB) | 5 | ILE A 23ALA A 249LEU A 300THR A 338ILE A 225 | None | 1.17A | 3prsA-2qneA:undetectable | 3prsA-2qneA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbn | TERMINASE LARGESUBUNIT (Bacillus phageSPP1) |
PF17288(Terminase_3C) | 5 | ILE A 328ALA A 320LEU A 274ILE A 373ILE A 291 | None | 1.14A | 3prsA-2wbnA:undetectable | 3prsA-2wbnA:18.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 6 | ILE A 73TYR A 75LEU A 121THR A 131ILE A 211ILE A 293 | NonePP6 A 327 (-3.8A)NoneNoneNoneNone | 0.88A | 3prsA-2wedA:47.9 | 3prsA-2wedA:54.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 6 | ILE A 73TYR A 75LEU A 121THR A 131ILE A 211THR A 217 | NonePP6 A 327 (-3.8A)NoneNoneNonePP6 A 327 (-4.5A) | 0.40A | 3prsA-2wedA:47.9 | 3prsA-2wedA:54.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7q | POSSIBLE THIAMINEBIOSYNTHESIS ENZYME (Candidaalbicans) |
PF09084(NMT1) | 5 | ASP A 225ALA A 227THR A 185ILE A 58ILE A 255 | None | 1.15A | 3prsA-2x7qA:undetectable | 3prsA-2x7qA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yrf | METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Bacillussubtilis) |
PF01008(IF-2B) | 5 | ALA A 68ILE A 131LEU A 107ILE A 45ILE A 20 | None | 1.04A | 3prsA-2yrfA:undetectable | 3prsA-2yrfA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxd | PROBABLECOBALT-PRECORRIN-6YC(15)-METHYLTRANSFERASE[DECARBOXYLATING] (Methanocaldococcusjannaschii) |
PF13847(Methyltransf_31) | 5 | ILE A 87ALA A 62LEU A 99ILE A 127ILE A 112 | None | 1.11A | 3prsA-2yxdA:undetectable | 3prsA-2yxdA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zle | PROTEASE DO (Escherichiacoli) |
PF00595(PDZ)PF13365(Trypsin_2) | 5 | ILE A 154ALA A 196LEU A 176THR A 111ILE A 19 | None | 1.11A | 3prsA-2zleA:undetectable | 3prsA-2zleA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2u | XYLOSIDASE/ARABINOSIDASE (Selenomonasruminantium) |
PF04616(Glyco_hydro_43)PF07081(DUF1349) | 5 | ILE A 294ALA A 262ILE A 111ILE A 87ILE A 72 | None | 1.09A | 3prsA-3c2uA:undetectable | 3prsA-3c2uA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dme | CONSERVED EXPORTEDPROTEIN (Bordetellapertussis) |
PF01266(DAO) | 5 | ALA A 35ILE A 19THR A 363THR A 171ILE A 5 | FAD A 500 (-3.6A)NoneNoneNoneNone | 1.21A | 3prsA-3dmeA:undetectable | 3prsA-3dmeA:22.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3emy | TRICHODERMA REESEIASPARTIC PROTEASE (Trichodermareesei) |
PF00026(Asp) | 5 | ASP A 8ILE A 73TYR A 75ILE A 299THR A 219 | None | 1.18A | 3prsA-3emyA:51.8 | 3prsA-3emyA:60.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3emy | TRICHODERMA REESEIASPARTIC PROTEASE (Trichodermareesei) |
PF00026(Asp) | 7 | ASP A 8ILE A 73TYR A 75LEU A 120ILE A 213THR A 219ILE A 297 | None | 0.56A | 3prsA-3emyA:51.8 | 3prsA-3emyA:60.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ia4 | DIHYDROFOLATEREDUCTASE (Moritellaprofunda) |
PF00186(DHFR_1) | 5 | ILE A 15ALA A 7LEU A 106ILE A 2ILE A 138 | NDP A 163 (-3.7A)NDP A 163 ( 3.9A)NoneNoneNone | 1.16A | 3prsA-3ia4A:undetectable | 3prsA-3ia4A:15.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3in1 | UNCHARACTERIZEDSUGAR KINASE YDJH (Escherichiacoli) |
PF00294(PfkB) | 5 | ILE A 73ALA A 12ILE A 267ILE A 142ILE A 156 | None | 1.00A | 3prsA-3in1A:undetectable | 3prsA-3in1A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kd8 | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Thermoplasmaacidophilum) |
PF01676(Metalloenzyme)PF10143(PhosphMutase) | 5 | ILE A 42ASP A 365LEU A 391ILE A 278ILE A 317 | None | 1.23A | 3prsA-3kd8A:undetectable | 3prsA-3kd8A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg9 | CURK (Lyngbyamajuscula) |
PF14765(PS-DH) | 5 | ILE A1034ALA A1006LEU A1238ILE A1148ILE A1204 | None | 1.11A | 3prsA-3kg9A:undetectable | 3prsA-3kg9A:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kum | DIPEPTIDE EPIMERASE (Enterococcusfaecalis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 66ALA A 101ILE A 54ILE A 290ILE A 277 | NoneNoneTYR A 356 (-4.5A)NoneNone | 1.11A | 3prsA-3kumA:undetectable | 3prsA-3kumA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lfu | DNA HELICASE II (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | ILE A 297TYR A 600LEU A 308ILE A 318ILE A 572 | None | 1.04A | 3prsA-3lfuA:undetectable | 3prsA-3lfuA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0a | TYROSINE-PROTEINPHOSPHATASE AUXILIN (Bos taurus) |
PF10409(PTEN_C2) | 5 | ILE A 170ALA A 132ILE A 327THR A 331ILE A 261 | None | 0.92A | 3prsA-3n0aA:undetectable | 3prsA-3n0aA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng0 | GLUTAMINE SYNTHETASE (Synechocystissp. PCC 6803) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 5 | ALA A 374ILE A 91THR A 76ILE A 226ILE A 245 | None | 1.07A | 3prsA-3ng0A:undetectable | 3prsA-3ng0A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qha | PUTATIVEOXIDOREDUCTASE (Mycobacteriumavium) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 5 | ALA A 88ILE A 103LEU A 111THR A 174ILE A 153 | None | 1.24A | 3prsA-3qhaA:undetectable | 3prsA-3qhaA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgg | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, PUREPROTEIN (Treponemadenticola) |
PF00731(AIRC) | 5 | ALA A 39TYR A 62LEU A 50ILE A 34ILE A 21 | None | 0.93A | 3prsA-3rggA:undetectable | 3prsA-3rggA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sl1 | ARGINASE (Plasmodiumfalciparum) |
PF00491(Arginase) | 5 | ALA A 332ILE A 320LEU A 401ILE A 294ILE A 270 | None | 1.15A | 3prsA-3sl1A:undetectable | 3prsA-3sl1A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tcs | RACEMASE, PUTATIVE (Roseobacterdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 334ALA A 339THR A 232ILE A 303ILE A 265 | PG4 A 372 ( 4.9A)NoneNoneNoneNone | 1.16A | 3prsA-3tcsA:undetectable | 3prsA-3tcsA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl2 | MALATE DEHYDROGENASE (Bacillusanthracis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ASP A 292ALA A 296ILE A 256LEU A 270THR A 131 | None | 1.08A | 3prsA-3tl2A:undetectable | 3prsA-3tl2A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw0 | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF00092(VWA) | 5 | ALA A 353ILE A 427TYR A 391THR A 388ILE A 509 | ACT A 702 (-4.4A)NoneNoneACT A 702 (-2.9A)None | 1.22A | 3prsA-3tw0A:undetectable | 3prsA-3tw0A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4f | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Roseovariusnubinhibens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 334ALA A 339THR A 232ILE A 303ILE A 265 | None | 1.25A | 3prsA-3u4fA:undetectable | 3prsA-3u4fA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vx6 | E1 (Kluyveromycesmarxianus) |
PF16420(ATG7_N) | 5 | ILE A 150ALA A 241ILE A 117ILE A 181THR A 228 | None | 1.18A | 3prsA-3vx6A:undetectable | 3prsA-3vx6A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wel | ALPHA-GLUCOSIDASE (Beta vulgaris) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16863(NtCtMGAM_N) | 5 | ILE A 311ALA A 556ILE A 281TYR A 283ILE A 286 | None | 1.13A | 3prsA-3welA:undetectable | 3prsA-3welA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5g | ANIONIC PEROXIDASE (Raphanussativus) |
PF00141(peroxidase) | 5 | ILE A 34ASP A 31LEU A 103THR A 128ILE A 140 | None | 1.24A | 3prsA-4a5gA:undetectable | 3prsA-4a5gA:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3s | ALDEHYDEDEHYDROGENASE (Lachnoclostridiumphytofermentans) |
PF00171(Aldedh) | 5 | ILE A 250ALA A 248ILE A 406TYR A 402THR A 408 | SO4 A1467 (-4.2A)NoneNoneNoneNone | 1.00A | 3prsA-4c3sA:undetectable | 3prsA-4c3sA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dd5 | ACETYL-COAACETYLTRANSFERASE (Clostridioidesdifficile) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ALA A 42ILE A 89LEU A 58ILE A 107ILE A 280 | None | 1.16A | 3prsA-4dd5A:undetectable | 3prsA-4dd5A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eze | HALOACIDDEHALOGENASE-LIKEHYDROLASE (Salmonellaenterica) |
PF12710(HAD) | 5 | ILE A 165ILE A 3TYR A 5LEU A 295ILE A 12 | None | 1.18A | 3prsA-4ezeA:undetectable | 3prsA-4ezeA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbh | PROTEIN SYNTHESISINHIBITOR I (Hordeum vulgare) |
PF00161(RIP) | 5 | ALA A 141ILE A 202LEU A 133ILE A 31ILE A 86 | None | 1.24A | 3prsA-4fbhA:undetectable | 3prsA-4fbhA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lkr | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 5 | ALA A 109ILE A 88LEU A 200THR A 127ILE A 194 | None | 1.16A | 3prsA-4lkrA:undetectable | 3prsA-4lkrA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lob | POLYPRENYLSYNTHETASE (Acinetobacterbaumannii) |
PF00348(polyprenyl_synt) | 5 | ILE A 258ALA A 246ILE A 171TYR A 167THR A 175 | None | 1.25A | 3prsA-4lobA:undetectable | 3prsA-4lobA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | ALA A 566ILE A 519TYR A 520ILE A 537THR A 564 | None | 0.97A | 3prsA-4rbnA:undetectable | 3prsA-4rbnA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoz | BETA-GALACTOSIDASE (Bifidobacteriumanimalis) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | ASP A 302ALA A 305LEU A 412ILE A 23ILE A 672 | None | 1.19A | 3prsA-4uozA:undetectable | 3prsA-4uozA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5k | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Trypanosomabrucei) |
PF00155(Aminotran_1_2) | 5 | ALA A 169ILE A 251LEU A 229ILE A 113ILE A 126 | None | 1.04A | 3prsA-4w5kA:undetectable | 3prsA-4w5kA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 5 | ALA A 289ILE A 278THR A 227THR A 250ILE A 2 | ANP A 401 (-3.5A)NoneNoneNoneNone | 1.21A | 3prsA-4wjmA:undetectable | 3prsA-4wjmA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg7 | SERINE/THREONINE-PROTEIN KINASE HIPA (Escherichiacoli) |
PF07804(HipA_C)PF13657(Couple_hipA) | 5 | ILE D 149ASP D 96LEU D 129ILE D 184ILE D 334 | None | 1.13A | 3prsA-4yg7D:undetectable | 3prsA-4yg7D:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c17 | MERB2 (Bacillusmegaterium) |
PF03243(MerB) | 5 | ILE A 29ALA A 79TYR A 11LEU A 204ILE A 168 | NoneNoneNoneNoneDTV A 303 ( 4.9A) | 1.24A | 3prsA-5c17A:undetectable | 3prsA-5c17A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e57 | TRANSCRIPTIONREGULATOR AMTR (Mycolicibacteriumsmegmatis) |
PF00440(TetR_N) | 5 | ILE A 173ALA A 118LEU A 125THR A 35ILE A 47 | None | 0.91A | 3prsA-5e57A:undetectable | 3prsA-5e57A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eku | ARGININEN-METHYLTRANSFERASE,PUTATIVE (Trypanosomabrucei) |
PF06325(PrmA) | 5 | ALA A 333ILE A 281LEU A 369THR A 176ILE A 173 | NoneNoneNoneNoneSAH A 401 ( 4.4A) | 1.20A | 3prsA-5ekuA:undetectable | 3prsA-5ekuA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fqd | DNA DAMAGE-BINDINGPROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | ALA A 154TYR A 84LEU A 135ILE A 79ILE A1068 | None | 1.15A | 3prsA-5fqdA:undetectable | 3prsA-5fqdA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h53 | SKELETAL MUSCLEMYOSIN HEAVY CHAINMYHC-EO/IIL (Oryctolaguscuniculus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | ASP A 384ALA A 386LEU A 429ILE A 351ILE A 291 | None | 1.20A | 3prsA-5h53A:undetectable | 3prsA-5h53A:17.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hct | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 10 | ILE A 10ASP A 11ALA A 16ILE A 77TYR A 79LEU A 125THR A 135ILE A 217THR A 223ILE A 300 | NoneNoneNoneNone61P A 406 (-4.3A)NoneNoneNonePG4 A 408 (-3.8A)61P A 406 (-4.0A) | 0.25A | 3prsA-5hctA:58.2 | 3prsA-5hctA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hct | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | ILE A 77TYR A 79LEU A 125THR A 135ILE A 302 | None61P A 406 (-4.3A)NoneNoneNone | 0.99A | 3prsA-5hctA:58.2 | 3prsA-5hctA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiw | CYTOCHROME P450CYP260B1 (Sorangiumcellulosum) |
PF00067(p450) | 5 | ALA A 344ILE A 203LEU A 91THR A 233ILE A 154 | HEM A 401 (-3.5A)NoneNoneHEM A 401 (-4.5A)None | 1.19A | 3prsA-5hiwA:undetectable | 3prsA-5hiwA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnb | POLY(A) RNAPOLYMERASE GLD-2RNP (RRM RNA BINDINGDOMAIN) CONTAINING (Caenorhabditiselegans) |
PF03828(PAP_assoc)no annotation | 5 | ILE E 193ILE A 653LEU A 628THR A 614ILE A 677 | None | 1.08A | 3prsA-5jnbE:undetectable | 3prsA-5jnbE:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jo7 | VETISPIRADIENESYNTHASE 1 (Hyoscyamusmuticus) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ILE A 90ALA A 83TYR A 222LEU A 232ILE A 553 | None | 1.14A | 3prsA-5jo7A:undetectable | 3prsA-5jo7A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l56 | PLEXIN-A1 (Mus musculus) |
PF01403(Sema)PF01437(PSI)PF01833(TIG) | 5 | ILE A 172ILE A 242TYR A 244LEU A 199ILE A 298 | None | 1.24A | 3prsA-5l56A:undetectable | 3prsA-5l56A:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mxp | - (-) |
no annotation | 5 | ILE A 122ALA A 115LEU A 37THR A 42ILE A 80 | None | 1.05A | 3prsA-5mxpA:undetectable | 3prsA-5mxpA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnp | N-TERMINALACETYLTRANSFERASE-LIKE PROTEIN (Chaetomiumthermophilum) |
PF12569(NARP1)PF13432(TPR_16) | 5 | ILE A 672ALA A 698TYR A 682ILE A 734ILE A 718 | None | 1.05A | 3prsA-5nnpA:undetectable | 3prsA-5nnpA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnp | N-TERMINALACETYLTRANSFERASE-LIKE PROTEIN (Chaetomiumthermophilum) |
PF12569(NARP1)PF13432(TPR_16) | 5 | ILE A 672ALA A 698TYR A 682LEU A 665ILE A 734 | None | 0.98A | 3prsA-5nnpA:undetectable | 3prsA-5nnpA:16.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5p60 | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 10 | ILE A 10ASP A 11ALA A 16ILE A 77TYR A 79LEU A 125THR A 135ILE A 217THR A 223ILE A 300 | None | 0.31A | 3prsA-5p60A:58.1 | 3prsA-5p60A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5p60 | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | ILE A 77TYR A 79LEU A 125THR A 135ILE A 302 | None | 1.03A | 3prsA-5p60A:58.1 | 3prsA-5p60A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5p60 | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | ILE A 77TYR A 79THR A 135ILE A 302THR A 223 | None | 0.96A | 3prsA-5p60A:58.1 | 3prsA-5p60A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT B (Methanothermobactersp. CaT2) |
PF00384(Molybdopterin) | 5 | ILE B 341ASP B 414ALA B 342THR B 257ILE B 37 | NoneMGD B 503 (-3.0A)MGD B 503 (-3.4A)NoneSF4 B 501 (-4.5A) | 1.16A | 3prsA-5t5iB:undetectable | 3prsA-5t5iB:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ugj | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Neisseriameningitidis) |
no annotation | 5 | ILE A 6LEU A 19THR A 29THR A 100ILE A 120 | None | 1.09A | 3prsA-5ugjA:undetectable | 3prsA-5ugjA:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujs | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Campylobacterjejuni) |
PF00275(EPSP_synthase) | 5 | ILE A 137ALA A 135ILE A 33THR A 75ILE A 214 | None | 1.10A | 3prsA-5ujsA:undetectable | 3prsA-5ujsA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uv2 | (+)-LIMONENESYNTHASE (Citrus sinensis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ILE A 124ALA A 117TYR A 257LEU A 267ILE A 590 | None | 1.23A | 3prsA-5uv2A:undetectable | 3prsA-5uv2A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v52 | T-CELLIMMUNORECEPTOR WITHIG AND ITIM DOMAINS (Homo sapiens) |
PF07686(V-set) | 5 | ILE A 77ALA A 67ILE A 33LEU A 95ILE A 27 | None | 1.19A | 3prsA-5v52A:undetectable | 3prsA-5v52A:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vm9 | PROTEIN ARGONAUTE-3 (Homo sapiens) |
no annotation | 5 | ASP A 538ILE A 593LEU A 650THR A 856ILE A 575 | None | 1.22A | 3prsA-5vm9A:undetectable | 3prsA-5vm9A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wfc | HISTONE-LYSINE-N-METHYLTRANSFERASE EZH2,POLYCOMB PROTEINSUZ12 CHIMERA (Chaetomiumthermophilum) |
no annotation | 5 | ILE B2580ILE B 510ILE B 865THR B 827ILE B 891 | None | 1.08A | 3prsA-5wfcB:undetectable | 3prsA-5wfcB:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn6 | OS07G0580900 PROTEIN (Oryza sativa) |
PF00348(polyprenyl_synt) | 5 | ILE A 223TYR A 219LEU A 296ILE A 201ILE A 213 | None | 1.20A | 3prsA-5xn6A:undetectable | 3prsA-5xn6A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxg | PILUS ASSEMBLYPROTEIN (Lactobacillusrhamnosus) |
no annotation | 5 | ILE A 409ALA A 392ILE A 475LEU A 443THR A 419 | None | 1.25A | 3prsA-5yxgA:undetectable | 3prsA-5yxgA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bhu | MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN 1 (Bos taurus) |
no annotation | 5 | ILE A1504ILE A1449LEU A1481THR A1447ILE A1342 | None | 1.19A | 3prsA-6bhuA:undetectable | 3prsA-6bhuA:0.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 5 | ASP A 779LEU A 765ILE A 863THR A 803ILE A 883 | None | 1.05A | 3prsA-6eojA:undetectable | 3prsA-6eojA:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6exs | PEPTIDE ABCTRANSPORTER PERMEASE (Staphylococcushominis) |
no annotation | 5 | ILE A 243ILE A 88THR A 93ILE A 106ILE A 78 | NoneNoneOLC A 512 (-4.7A)NoneNone | 1.19A | 3prsA-6exsA:undetectable | 3prsA-6exsA:14.18 |