SIMILAR PATTERNS OF AMINO ACIDS FOR 3PP7_B_SVRB499_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 8 | THR A 26PRO A 29ARG A 49ASN A 51HIS A 54GLY A 55GLY A 333ALA A 336 | NoneNonePGA A1005 (-3.4A) K A1002 (-3.6A)NoneNoneNoneNone | 0.44A | 3pp7B-1a3xA:59.8 | 3pp7B-1a3xA:48.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 7 | THR A 26PRO A 29HIS A 54GLY A 55GLY A 333ALA A 336LYS A 337 | None | 0.69A | 3pp7B-1a3xA:59.8 | 3pp7B-1a3xA:48.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6s | O-ACETYLSERINESULFHYDRYLASE (Salmonellaenterica) |
PF00291(PALP) | 5 | THR A 113PRO A 67GLY A 70GLY A 121ALA A 122 | NoneNoneMET A 401 (-4.2A)NoneNone | 1.23A | 3pp7B-1d6sA:4.2 | 3pp7B-1d6sA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7b | CELLOBIOSEDEHYDROGENASE (Phanerochaetechrysosporium) |
PF16010(CDH-cyt) | 5 | ASN A 67GLY A 89TYR A 90GLY A 62ALA A 64 | NoneNoneHEM A 401 (-4.0A)NoneHEM A 401 (-3.8A) | 1.26A | 3pp7B-1d7bA:undetectable | 3pp7B-1d7bA:15.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1e0t | PYRUVATE KINASE (Escherichiacoli) |
PF00224(PK)PF02887(PK_C) | 7 | THR A 9PRO A 12ARG A 32ASN A 34HIS A 37GLY A 38GLY A 313 | None | 0.61A | 3pp7B-1e0tA:49.8 | 3pp7B-1e0tA:42.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | THR A 290ASN A 266GLY A 177GLY A 292ALA A 264 | None CA A 751 ( 3.2A)PQQ A 701 (-3.7A)NoneNone | 1.47A | 3pp7B-1flgA:undetectable | 3pp7B-1flgA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnf | FIBRONECTIN (Homo sapiens) |
PF00041(fn3) | 5 | THR A1353ASN A1401TYR A1357GLY A1300ALA A1352 | None | 1.39A | 3pp7B-1fnfA:undetectable | 3pp7B-1fnfA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpg | GLUTAMIC ACIDSPECIFIC PROTEASE (Streptomycesgriseus) |
no annotation | 5 | THR A 183HIS A 213GLY A 197GLY A 224ALA A 190 | None | 1.19A | 3pp7B-1hpgA:undetectable | 3pp7B-1hpgA:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzo | BETA-LACTAMASE (Proteusvulgaris) |
PF13354(Beta-lactamase2) | 5 | THR A 159GLY A 45TYR A 264ALA A 185LYS A 188 | None | 1.33A | 3pp7B-1hzoA:undetectable | 3pp7B-1hzoA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nne | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | ASN A 585HIS A 696TYR A 737GLY A 588ALA A 587 | BEF A 998 (-3.4A)SO4 A 852 (-4.3A)NoneADP A 999 (-3.4A)ADP A 999 (-4.4A) | 1.46A | 3pp7B-1nneA:undetectable | 3pp7B-1nneA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ope | SUCCINYL-COA:3-KETOACID-COENZYME ATRANSFERASE (Sus scrofa) |
PF01144(CoA_trans) | 5 | PRO A 194ASN A 51GLY A 23GLY A 100ALA A 103 | None | 1.36A | 3pp7B-1opeA:undetectable | 3pp7B-1opeA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p5q | FK506-BINDINGPROTEIN 4 (Homo sapiens) |
PF00254(FKBP_C)PF00515(TPR_1)PF07719(TPR_2) | 5 | PRO A 201GLY A 176TYR A 245GLY A 228ALA A 226 | None | 1.29A | 3pp7B-1p5qA:undetectable | 3pp7B-1p5qA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s5a | HYPOTHETICAL PROTEINYESE (Bacillussubtilis) |
PF12680(SnoaL_2) | 5 | THR A 114ASN A 85GLY A 117ALA A 9LYS A 8 | None | 1.33A | 3pp7B-1s5aA:undetectable | 3pp7B-1s5aA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1txz | HYPOTHETICAL 32.1KDA PROTEIN INADH3-RCA1 INTERGENICREGION (Saccharomycescerevisiae) |
PF14519(Macro_2) | 5 | THR A 29PRO A 191ASN A 25GLY A 196GLY A 52 | NoneAPR A 285 ( 4.9A)NoneAPR A 285 (-3.2A)SO4 A 288 ( 3.4A) | 1.21A | 3pp7B-1txzA:undetectable | 3pp7B-1txzA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xat | XENOBIOTICACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00132(Hexapep) | 5 | PRO A 107GLY A 78TYR A 105GLY A 128ALA A 108 | None | 1.49A | 3pp7B-1xatA:undetectable | 3pp7B-1xatA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a2o | HYPOTHETICAL PROTEINBT3146 (Bacteroidesthetaiotaomicron) |
no annotation | 5 | THR A 237PRO A 69GLY A 65TYR A 185ALA A 71 | None | 1.39A | 3pp7B-2a2oA:undetectable | 3pp7B-2a2oA:17.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2e28 | PYRUVATE KINASE (Geobacillusstearothermophilus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 8 | THR A 10PRO A 13ARG A 33ASN A 35HIS A 38GLY A 39GLY A 314ALA A 317 | None | 0.49A | 3pp7B-2e28A:59.4 | 3pp7B-2e28A:38.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2egu | CYSTEINE SYNTHASE (Geobacilluskaustophilus) |
PF00291(PALP) | 5 | THR A 117PRO A 71GLY A 77GLY A 125ALA A 126 | None | 1.33A | 3pp7B-2eguA:3.4 | 3pp7B-2eguA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hp3 | IDS-EPIMERASE (Agrobacteriumtumefaciens) |
PF03972(MmgE_PrpD) | 5 | PRO A 397GLY A 373TYR A 272GLY A 280ALA A 279 | NoneUNX A1212 ( 3.6A)NoneNoneNone | 1.40A | 3pp7B-2hp3A:undetectable | 3pp7B-2hp3A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2isq | CYSTEINE SYNTHASE (Arabidopsisthaliana) |
PF00291(PALP) | 5 | THR A 119PRO A 73GLY A 76GLY A 127ALA A 128 | None | 1.25A | 3pp7B-2isqA:4.0 | 3pp7B-2isqA:23.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qed | HYDROXYACYLGLUTATHIONE HYDROLASE (Salmonellaenterica) |
PF00753(Lactamase_B)PF16123(HAGH_C) | 5 | THR A 86PRO A 77TYR A 117GLY A 84ALA A 85 | None | 1.35A | 3pp7B-2qedA:undetectable | 3pp7B-2qedA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ux8 | GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Sphingomonaselodea) |
PF00483(NTP_transferase) | 5 | PRO A 12HIS A 113GLY A 112GLY A 60ALA A 14 | None | 1.08A | 3pp7B-2ux8A:4.6 | 3pp7B-2ux8A:19.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vgi | PYRUVATE KINASEISOZYMES R/L (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 7 | THR A 93ARG A 116ASN A 118HIS A 121GLY A 406ALA A 409LYS A 410 | NonePGA A1575 (-3.7A) K A1576 (-4.0A)NoneNoneNoneNone | 0.77A | 3pp7B-2vgiA:58.5 | 3pp7B-2vgiA:47.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2vgi | PYRUVATE KINASEISOZYMES R/L (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 9 | THR A 93PRO A 96ARG A 116ASN A 118HIS A 121GLY A 122TYR A 126GLY A 406ALA A 409 | NoneNonePGA A1575 (-3.7A) K A1576 (-4.0A)NoneNoneNoneNoneNone | 0.54A | 3pp7B-2vgiA:58.5 | 3pp7B-2vgiA:47.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zkg | E3 UBIQUITIN-PROTEINLIGASE UHRF1 (Mus musculus) |
PF02182(SAD_SRA) | 5 | ASN A 509GLY A 485TYR A 483GLY A 461ALA A 462 | None | 1.38A | 3pp7B-2zkgA:undetectable | 3pp7B-2zkgA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwv | PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE (Thermusthermophilus) |
PF05175(MTS) | 5 | ASN A 53HIS A 35GLY A 57GLY A 139ALA A 138 | None | 1.32A | 3pp7B-2zwvA:3.5 | 3pp7B-2zwvA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zyi | LIPASE, PUTATIVE (Archaeoglobusfulgidus) |
PF00561(Abhydrolase_1) | 5 | THR A 62PRO A 425GLY A 79GLY A 33ALA A 32 | NoneNoneNoneSTE A 500 ( 4.0A)STE A 500 (-4.7A) | 1.37A | 3pp7B-2zyiA:undetectable | 3pp7B-2zyiA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 5 | THR A 68GLY A 76TYR A 28GLY A 99ALA A 101 | None | 1.49A | 3pp7B-3ai7A:undetectable | 3pp7B-3ai7A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNITMEMBRANE-BOUNDHYDROGENASE SMALLSUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 5 | ARG B 32ASN A 228HIS A 221GLY A 225GLY A 77 | None | 1.27A | 3pp7B-3ayxB:undetectable | 3pp7B-3ayxB:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b97 | ALPHA-ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | THR A 204ASN A 205GLY A 159GLY A 200ALA A 203 | None | 1.44A | 3pp7B-3b97A:6.6 | 3pp7B-3b97A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bfg | CLASS ABETA-LACTAMASE SED1 (Citrobactersedlakii) |
PF13354(Beta-lactamase2) | 5 | THR A 159GLY A 45TYR A 264ALA A 185LYS A 188 | None | 1.30A | 3pp7B-3bfgA:undetectable | 3pp7B-3bfgA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg9 | PYRUVATECARBOXYLASE,MITOCHONDRIAL (Homo sapiens) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 5 | THR A 652PRO A 909ASN A 653GLY A 953GLY A 650 | None | 1.47A | 3pp7B-3bg9A:5.8 | 3pp7B-3bg9A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cdx | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Rhodobactersphaeroides) |
PF04952(AstE_AspA) | 5 | THR A 160ASN A 186HIS A 259GLY A 182ALA A 183 | None | 1.35A | 3pp7B-3cdxA:undetectable | 3pp7B-3cdxA:22.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3eoe | PYRUVATE KINASE (Toxoplasmagondii) |
PF00224(PK)PF02887(PK_C) | 8 | THR A 43PRO A 46ARG A 66ASN A 68HIS A 71GLY A 72GLY A 348ALA A 351 | None | 0.24A | 3pp7B-3eoeA:54.6 | 3pp7B-3eoeA:42.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2i | ESTERASE (Xanthomonasoryzae) |
PF03583(LIP) | 5 | PRO A 340ASN A 335GLY A 332GLY A 226ALA A 337 | None | 1.49A | 3pp7B-3h2iA:4.6 | 3pp7B-3h2iA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3v | PROBABLE SECRETEDSOLUTE-BINDINGLIPOPROTEIN (Streptomycescoelicolor) |
PF01547(SBP_bac_1) | 5 | THR A 295PRO A 288ASN A 163GLY A 293ALA A 292 | None | 1.48A | 3pp7B-3i3vA:undetectable | 3pp7B-3i3vA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juj | UDP-GLUCOSEPYROPHOSPHORYLASE(GALU) (Helicobacterpylori) |
PF00483(NTP_transferase) | 5 | PRO A 8HIS A 110GLY A 109GLY A 56ALA A 10 | None | 1.12A | 3pp7B-3jujA:4.3 | 3pp7B-3jujA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kal | HOMOGLUTATHIONESYNTHETASE (Glycine max) |
PF03199(GSH_synthase)PF03917(GSH_synth_ATP) | 5 | THR A 175PRO A 324ARG A 153ASN A 171GLY A 332 | HGS A 501 (-4.7A)NoneHGS A 501 ( 2.8A) MG A 502 (-2.9A) MG A 504 (-3.8A) | 1.43A | 3pp7B-3kalA:undetectable | 3pp7B-3kalA:21.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3khd | PYRUVATE KINASE (Plasmodiumfalciparum) |
PF00224(PK)PF02887(PK_C) | 8 | THR A 53PRO A 56ARG A 76ASN A 78HIS A 81GLY A 82GLY A 357ALA A 360 | None | 0.52A | 3pp7B-3khdA:56.6 | 3pp7B-3khdA:43.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l9y | SUPEROXIDE DISMUTASE[CU-ZN] (Bombyx mori) |
PF00080(Sod_Cu) | 5 | THR A 137HIS A 47GLY A 81GLY A 141ALA A 140 | None CU A 156 (-3.2A)NoneNoneNone | 1.39A | 3pp7B-3l9yA:undetectable | 3pp7B-3l9yA:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ln6 | GLUTATHIONEBIOSYNTHESISBIFUNCTIONAL PROTEINGSHAB (Streptococcusagalactiae) |
PF01071(GARS_A)PF04262(Glu_cys_ligase) | 5 | THR A 384PRO A 196HIS A 336GLY A 387ALA A 386 | None | 1.49A | 3pp7B-3ln6A:undetectable | 3pp7B-3ln6A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mh9 | LIPOPROTEIN LPRG (Mycobacteriumtuberculosis) |
no annotation | 5 | THR C 193GLY C 212GLY C 170ALA C 192LYS C 171 | None | 1.30A | 3pp7B-3mh9C:undetectable | 3pp7B-3mh9C:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mha | LIPOPROTEIN LPRG (Mycobacteriumtuberculosis) |
PF07161(LppX_LprAFG) | 5 | THR A 193GLY A 212GLY A 170ALA A 192LYS A 171 | None | 1.28A | 3pp7B-3mhaA:undetectable | 3pp7B-3mhaA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mos | TRANSKETOLASE (Homo sapiens) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | THR A 511PRO A 534GLY A 569GLY A 509ALA A 508 | None | 1.38A | 3pp7B-3mosA:2.4 | 3pp7B-3mosA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwz | BH2602 PROTEIN (Bacillushalodurans) |
PF03061(4HBT) | 5 | ASN A 114HIS A 116TYR A 117GLY A 144LYS A 145 | None | 1.44A | 3pp7B-3nwzA:undetectable | 3pp7B-3nwzA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyw | PUTATIVEOXIDOREDUCTASE (Bacteroidesthetaiotaomicron) |
PF00106(adh_short) | 5 | THR A 27PRO A 59ASN A 53GLY A 29ALA A 26 | None | 1.49A | 3pp7B-3nywA:undetectable | 3pp7B-3nywA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3p | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Rubrobacterxylanophilus) |
PF00535(Glycos_transf_2) | 5 | PRO A 206ARG A 254GLY A 180GLY A 209ALA A 208 | None MG A 339 ( 4.7A)NoneGDD A 340 (-3.5A)None | 1.36A | 3pp7B-3o3pA:5.0 | 3pp7B-3o3pA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfk | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | THR A 346ASN A 459GLY A 466TYR A 469ALA A 347 | NoneAKG A 514 ( 4.0A)NoneNoneNone | 1.28A | 3pp7B-3qfkA:5.0 | 3pp7B-3qfkA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtg | PYRUVATE KINASE (Pyrobaculumaerophilum) |
PF00224(PK)PF02887(PK_C) | 6 | THR A 22PRO A 25ARG A 46ASN A 48HIS A 51ALA A 326 | None | 0.47A | 3pp7B-3qtgA:45.8 | 3pp7B-3qtgA:29.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qv9 | PYRUVATE KINASE 2 (Trypanosomacruzi) |
PF00224(PK)PF02887(PK_C) | 8 | THR A 27ARG A 50ASN A 52HIS A 55GLY A 56GLY A 332ALA A 335LYS A 336 | PO4 A 501 (-3.5A)PO4 A 501 (-3.7A) K A 500 ( 3.5A)NoneNonePO4 A 501 (-3.6A)PO4 A 501 (-3.6A)PO4 A 501 ( 4.9A) | 1.24A | 3pp7B-3qv9A:69.2 | 3pp7B-3qv9A:75.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qv9 | PYRUVATE KINASE 2 (Trypanosomacruzi) |
PF00224(PK)PF02887(PK_C) | 9 | THR A 27PRO A 30ARG A 50ASN A 52GLY A 56TYR A 60GLY A 332ALA A 335LYS A 336 | PO4 A 501 (-3.5A)NonePO4 A 501 (-3.7A) K A 500 ( 3.5A)NoneNonePO4 A 501 (-3.6A)PO4 A 501 (-3.6A)PO4 A 501 ( 4.9A) | 0.60A | 3pp7B-3qv9A:69.2 | 3pp7B-3qv9A:75.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t05 | PYRUVATE KINASE (Staphylococcusaureus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 8 | THR A 9PRO A 12ARG A 32ASN A 34HIS A 37GLY A 38GLY A 312ALA A 315 | None | 0.43A | 3pp7B-3t05A:57.6 | 3pp7B-3t05A:36.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t69 | PUTATIVE2-DEHYDRO-3-DEOXYGALACTONOKINASE (Sinorhizobiummeliloti) |
PF05035(DGOK) | 5 | THR A 42HIS A 55GLY A 54GLY A 39ALA A 43 | None | 1.47A | 3pp7B-3t69A:2.7 | 3pp7B-3t69A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tev | GLYCOSYL HYROLASE,FAMILY 3 (Deinococcusradiodurans) |
PF00933(Glyco_hydro_3) | 5 | THR A 107ASN A 111HIS A 165GLY A 158ALA A 160 | None | 1.30A | 3pp7B-3tevA:6.2 | 3pp7B-3tevA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3umm | PHOSPHORIBOSYLFORMYLGLYCINAMIDINESYNTHASE (Salmonellaenterica) |
PF02769(AIRS_C)PF13507(GATase_5) | 5 | THR A 322PRO A 328ASN A 259GLY A 314GLY A 325 | NoneNoneANP A2001 (-3.7A)NoneNone | 1.48A | 3pp7B-3ummA:undetectable | 3pp7B-3ummA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbo | GENOME POLYPROTEIN,CAPSID PROTEIN VP2 (Enterovirus A) |
PF00073(Rhv) | 5 | PRO B 152HIS B 278TYR B 171GLY B 282LYS B 150 | None | 1.11A | 3pp7B-3vboB:undetectable | 3pp7B-3vboB:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wcx | SPHINGOMYELINASE C (Streptomycesgriseocarneus) |
PF03372(Exo_endo_phos) | 5 | THR A 58ASN A 57HIS A 191GLY A 234ALA A 95 | NoneSIN A 402 ( 4.1A)SIN A 402 (-4.1A)NoneNone | 1.41A | 3pp7B-3wcxA:undetectable | 3pp7B-3wcxA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfz | LACTO-N-BIOSEPHOSPHORYLASE (Bifidobacteriumlongum) |
PF09508(Lact_bio_phlase)PF17385(LBP_M)PF17386(LBP_C) | 5 | ARG A 275ASN A 268GLY A 235GLY A 264ALA A 266 | None | 1.12A | 3pp7B-3wfzA:10.2 | 3pp7B-3wfzA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfz | LACTO-N-BIOSEPHOSPHORYLASE (Bifidobacteriumlongum) |
PF09508(Lact_bio_phlase)PF17385(LBP_M)PF17386(LBP_C) | 5 | THR A 342PRO A 463GLY A 472GLY A 338ALA A 461 | None | 1.39A | 3pp7B-3wfzA:10.2 | 3pp7B-3wfzA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wlx | LOW SPECIFICITYL-THREONINE ALDOLASE (Escherichiacoli) |
no annotation | 5 | PRO B 100ASN B 84GLY B 79GLY B 91ALA B 92 | None | 1.41A | 3pp7B-3wlxB:undetectable | 3pp7B-3wlxB:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wyh | LYSOZYME G (Struthiocamelus) |
PF01464(SLT) | 5 | ARG A 35HIS A 183GLY A 184TYR A 185ALA A 38 | None | 1.42A | 3pp7B-3wyhA:undetectable | 3pp7B-3wyhA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 5 | THR A 501ASN A 546GLY A 590TYR A 636GLY A 514 | None | 0.89A | 3pp7B-4a2lA:undetectable | 3pp7B-4a2lA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ako | SPORE COAT PROTEIN A (Bacillussubtilis) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | PRO A 414GLY A 445TYR A 441GLY A 376ALA A 375 | None | 1.31A | 3pp7B-4akoA:undetectable | 3pp7B-4akoA:22.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4drs | PYRUVATE KINASE (Cryptosporidiumparvum) |
PF00224(PK)PF02887(PK_C) | 8 | THR A 51PRO A 54ARG A 74ASN A 76HIS A 79GLY A 80GLY A 363ALA A 366 | ACT A 605 ( 4.2A)NoneGOL A 603 ( 3.6A)GOL A 603 ( 3.3A)ACT A 606 (-4.0A)ACT A 606 (-4.0A)ACT A 605 (-3.7A)ACT A 605 ( 4.0A) | 0.36A | 3pp7B-4drsA:56.3 | 3pp7B-4drsA:42.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ewg | BETA-KETOACYLSYNTHASE (Paraburkholderiaphymatum) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | PRO A 359ARG A 220ASN A 362GLY A 29TYR A 332 | None | 1.41A | 3pp7B-4ewgA:undetectable | 3pp7B-4ewgA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjh | PHOSPHOMANNOMUTASE (Brucellamelitensis) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | THR A 241PRO A 85TYR A 159GLY A 243ALA A 245 | NoneNoneNoneSEP A 104 ( 4.6A)None | 1.41A | 3pp7B-4hjhA:4.0 | 3pp7B-4hjhA:23.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hyv | PYRUVATE KINASE 1 (Trypanosomabrucei) |
PF00224(PK)PF02887(PK_C) | 10 | THR A 27PRO A 30ARG A 50ASN A 52HIS A 55GLY A 56TYR A 60GLY A 332ALA A 335LYS A 336 | NoneNonePEP A1003 (-3.8A) K A1002 (-3.3A)NoneNoneNoneNoneNoneNone | 0.48A | 3pp7B-4hyvA:67.4 | 3pp7B-4hyvA:74.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 5 | THR A 434PRO A 440ASN A 437GLY A 221ALA A 433 | NoneNoneNone K A 504 (-3.5A)None | 1.40A | 3pp7B-4j9uA:undetectable | 3pp7B-4j9uA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kgb | SUCCINYL-COA:3-KETOACID-COENZYME ATRANSFERASE (Drosophilamelanogaster) |
PF01144(CoA_trans) | 5 | PRO A 227ASN A 84GLY A 56GLY A 133ALA A 136 | None | 1.33A | 3pp7B-4kgbA:undetectable | 3pp7B-4kgbA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4law | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEFKBP4 (Homo sapiens) |
PF00254(FKBP_C) | 5 | PRO A 201GLY A 176TYR A 245GLY A 228ALA A 226 | None | 1.29A | 3pp7B-4lawA:undetectable | 3pp7B-4lawA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lz6 | BH2163 PROTEIN (Bacillushalodurans) |
PF01554(MatE) | 5 | THR A 57ASN A 263GLY A 127GLY A 276ALA A 54 | None | 1.40A | 3pp7B-4lz6A:undetectable | 3pp7B-4lz6A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nap | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 7 (Desulfovibrioalaskensis) |
PF03480(DctP) | 5 | THR A 149PRO A 152GLY A 116GLY A 270ALA A 120 | None | 1.31A | 3pp7B-4napA:undetectable | 3pp7B-4napA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p48 | ANTIBODY SCFV 180 (Gallus gallus) |
PF07686(V-set) | 5 | PRO A 98GLY A 233TYR A 234GLY A 24ALA A 92 | None | 1.14A | 3pp7B-4p48A:undetectable | 3pp7B-4p48A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qhx | UNCHARACTERIZEDPROTEIN (Bacteroidescaccae) |
PF11958(DUF3472)PF16871(DUF5077) | 5 | HIS A 318GLY A 164TYR A 165GLY A 203ALA A 194 | PEG A 518 (-4.5A)NoneNoneNoneNone | 1.24A | 3pp7B-4qhxA:undetectable | 3pp7B-4qhxA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2v | CYSTEINE SYNTHETASE (Helicobacterpylori) |
PF00291(PALP) | 5 | THR A 118PRO A 72GLY A 75GLY A 126ALA A 127 | None | 1.26A | 3pp7B-4r2vA:3.9 | 3pp7B-4r2vA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxt | SUGAR ABCTRANSPORTER (Agrobacteriumtumefaciens) |
PF13407(Peripla_BP_4) | 5 | PRO A 172ARG A 180GLY A 205GLY A 175ALA A 174 | NoneARA A 401 (-3.0A)NoneNoneNone | 1.50A | 3pp7B-4rxtA:3.7 | 3pp7B-4rxtA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w4t | MXAA (Stigmatellaaurantiaca) |
PF07993(NAD_binding_4) | 5 | ASN A1259GLY A1310TYR A1252GLY A1218ALA A1257 | None | 1.32A | 3pp7B-4w4tA:undetectable | 3pp7B-4w4tA:21.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yj5 | PYRUVATE KINASE PKM (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 10 | THR A 50PRO A 53ARG A 73ASN A 75HIS A 78GLY A 79TYR A 83GLY A 363ALA A 366LYS A 367 | NoneNonePYR A 601 ( 4.7A) MG A 602 (-3.2A)NoneNoneNoneNoneNoneNone | 0.48A | 3pp7B-4yj5A:49.3 | 3pp7B-4yj5A:49.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4za3 | RRNA N-GLYCOSIDASE (Momordicacharantia) |
PF00652(Ricin_B_lectin) | 5 | THR B 179ARG B 181GLY B 208ALA B 124LYS B 125 | None | 1.38A | 3pp7B-4za3B:undetectable | 3pp7B-4za3B:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4p | UBIQUITIN-CONJUGATING ENZYME E2 Z (Homo sapiens) |
PF00179(UQ_con) | 5 | THR A 218PRO A 179ASN A 220HIS A 223TYR A 240 | None | 1.42A | 3pp7B-5a4pA:undetectable | 3pp7B-5a4pA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7n | MTA/SAH NUCLEOSIDASE (Aeromonashydrophila) |
PF01048(PNP_UDP_1) | 5 | ASN A 200HIS A 108GLY A 106GLY A 127ALA A 196 | NoneNoneSAH A 301 (-3.2A)NoneNone | 1.16A | 3pp7B-5b7nA:2.1 | 3pp7B-5b7nA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7n | MTA/SAH NUCLEOSIDASE (Aeromonashydrophila) |
PF01048(PNP_UDP_1) | 5 | ASN A 200HIS A 108GLY A 107GLY A 127ALA A 196 | None | 1.31A | 3pp7B-5b7nA:2.1 | 3pp7B-5b7nA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 5 | PRO A 263HIS A 212GLY A 220TYR A 246ALA A 305 | None | 1.35A | 3pp7B-5bp8A:undetectable | 3pp7B-5bp8A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7l | CONTACTIN-2 (Mus musculus) |
PF00041(fn3) | 5 | PRO A 782ASN A 894GLY A 844GLY A 724ALA A 810 | None | 1.15A | 3pp7B-5e7lA:undetectable | 3pp7B-5e7lA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ek8 | LIPOXYGENASE (Cyanothece sp.PCC 8801) |
PF00305(Lipoxygenase) | 5 | PRO A 104GLY A 88TYR A 102GLY A 108ALA A 107 | None | 1.48A | 3pp7B-5ek8A:undetectable | 3pp7B-5ek8A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epg | ALDEHYDE OXIDASE (Homo sapiens) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | THR A 932PRO A 926GLY A1276TYR A1215ALA A 929 | None | 1.31A | 3pp7B-5epgA:undetectable | 3pp7B-5epgA:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fm8 | MYOMESIN-1 (Homo sapiens) |
PF00041(fn3) | 5 | PRO A 513ASN A 588GLY A 543TYR A 544ALA A 511 | None | 1.38A | 3pp7B-5fm8A:undetectable | 3pp7B-5fm8A:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gk2 | KETOSYNTHASE STLD (Photorhabduslaumondii) |
PF08541(ACP_syn_III_C) | 5 | THR A 122GLY A 198TYR A 344GLY A 124ALA A 128 | None | 1.32A | 3pp7B-5gk2A:undetectable | 3pp7B-5gk2A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i1f | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Burkholderiavietnamiensis) |
PF00483(NTP_transferase) | 5 | PRO A 10HIS A 113GLY A 112GLY A 58ALA A 12 | UPG A 301 (-4.3A)NoneNoneNoneUPG A 301 (-3.2A) | 1.13A | 3pp7B-5i1fA:4.6 | 3pp7B-5i1fA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldf | GLUTAMINE SYNTHETASE (Salmonellaenterica) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 5 | THR A 315PRO A 363ASN A 317GLY A 265ALA A 364 | None | 1.02A | 3pp7B-5ldfA:undetectable | 3pp7B-5ldfA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thm | ESTERASE-6 (Drosophilamelanogaster) |
PF00135(COesterase) | 5 | PRO A 62ASN A 119HIS A 105GLY A 114ALA A 115 | MLY A 60 ( 4.3A)NoneNoneNoneNone | 1.49A | 3pp7B-5thmA:undetectable | 3pp7B-5thmA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhs | SUGAR TRANSPORTERSEMISWEET (Leptospirabiflexa) |
PF04193(PQ-loop) | 5 | PRO A 59GLY A 6TYR A 7GLY A 52ALA A 57 | None | 1.38A | 3pp7B-5uhsA:undetectable | 3pp7B-5uhsA:10.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wrp | PYRUVATE KINASE (Mycobacteriumtuberculosis) |
no annotation | 7 | THR A 10PRO A 13ARG A 33ASN A 35HIS A 38GLY A 39GLY A 311 | None | 0.57A | 3pp7B-5wrpA:52.5 | 3pp7B-5wrpA:36.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETARNA POLYMERASESUBUNIT ABC10-ALPHA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF03604(DNA_RNApol_7kD)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | THR B 956PRO L 47ARG B 107GLY L 54GLY B 960 | None | 1.24A | 3pp7B-5xogB:undetectable | 3pp7B-5xogB:16.79 |