SIMILAR PATTERNS OF AMINO ACIDS FOR 3PP7_B_SVRB499

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae)
PF00224
(PK)
PF02887
(PK_C)
8 THR A  26
PRO A  29
ARG A  49
ASN A  51
HIS A  54
GLY A  55
GLY A 333
ALA A 336
None
None
PGA  A1005 (-3.4A)
K  A1002 (-3.6A)
None
None
None
None
0.44A 3pp7B-1a3xA:
59.8
3pp7B-1a3xA:
48.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae)
PF00224
(PK)
PF02887
(PK_C)
7 THR A  26
PRO A  29
HIS A  54
GLY A  55
GLY A 333
ALA A 336
LYS A 337
None
0.69A 3pp7B-1a3xA:
59.8
3pp7B-1a3xA:
48.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6s O-ACETYLSERINE
SULFHYDRYLASE


(Salmonella
enterica)
PF00291
(PALP)
5 THR A 113
PRO A  67
GLY A  70
GLY A 121
ALA A 122
None
None
MET  A 401 (-4.2A)
None
None
1.23A 3pp7B-1d6sA:
4.2
3pp7B-1d6sA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d7b CELLOBIOSE
DEHYDROGENASE


(Phanerochaete
chrysosporium)
PF16010
(CDH-cyt)
5 ASN A  67
GLY A  89
TYR A  90
GLY A  62
ALA A  64
None
None
HEM  A 401 (-4.0A)
None
HEM  A 401 (-3.8A)
1.26A 3pp7B-1d7bA:
undetectable
3pp7B-1d7bA:
15.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e0t PYRUVATE KINASE

(Escherichia
coli)
PF00224
(PK)
PF02887
(PK_C)
7 THR A   9
PRO A  12
ARG A  32
ASN A  34
HIS A  37
GLY A  38
GLY A 313
None
0.61A 3pp7B-1e0tA:
49.8
3pp7B-1e0tA:
42.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flg PROTEIN
(QUINOPROTEIN
ETHANOL
DEHYDROGENASE)


(Pseudomonas
aeruginosa)
PF01011
(PQQ)
PF13360
(PQQ_2)
5 THR A 290
ASN A 266
GLY A 177
GLY A 292
ALA A 264
None
CA  A 751 ( 3.2A)
PQQ  A 701 (-3.7A)
None
None
1.47A 3pp7B-1flgA:
undetectable
3pp7B-1flgA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnf FIBRONECTIN

(Homo sapiens)
PF00041
(fn3)
5 THR A1353
ASN A1401
TYR A1357
GLY A1300
ALA A1352
None
1.39A 3pp7B-1fnfA:
undetectable
3pp7B-1fnfA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hpg GLUTAMIC ACID
SPECIFIC PROTEASE


(Streptomyces
griseus)
no annotation 5 THR A 183
HIS A 213
GLY A 197
GLY A 224
ALA A 190
None
1.19A 3pp7B-1hpgA:
undetectable
3pp7B-1hpgA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzo BETA-LACTAMASE

(Proteus
vulgaris)
PF13354
(Beta-lactamase2)
5 THR A 159
GLY A  45
TYR A 264
ALA A 185
LYS A 188
None
1.33A 3pp7B-1hzoA:
undetectable
3pp7B-1hzoA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS


(Thermus
aquaticus)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III)
5 ASN A 585
HIS A 696
TYR A 737
GLY A 588
ALA A 587
BEF  A 998 (-3.4A)
SO4  A 852 (-4.3A)
None
ADP  A 999 (-3.4A)
ADP  A 999 (-4.4A)
1.46A 3pp7B-1nneA:
undetectable
3pp7B-1nneA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ope SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE


(Sus scrofa)
PF01144
(CoA_trans)
5 PRO A 194
ASN A  51
GLY A  23
GLY A 100
ALA A 103
None
1.36A 3pp7B-1opeA:
undetectable
3pp7B-1opeA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p5q FK506-BINDING
PROTEIN 4


(Homo sapiens)
PF00254
(FKBP_C)
PF00515
(TPR_1)
PF07719
(TPR_2)
5 PRO A 201
GLY A 176
TYR A 245
GLY A 228
ALA A 226
None
1.29A 3pp7B-1p5qA:
undetectable
3pp7B-1p5qA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5a HYPOTHETICAL PROTEIN
YESE


(Bacillus
subtilis)
PF12680
(SnoaL_2)
5 THR A 114
ASN A  85
GLY A 117
ALA A   9
LYS A   8
None
1.33A 3pp7B-1s5aA:
undetectable
3pp7B-1s5aA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txz HYPOTHETICAL 32.1
KDA PROTEIN IN
ADH3-RCA1 INTERGENIC
REGION


(Saccharomyces
cerevisiae)
PF14519
(Macro_2)
5 THR A  29
PRO A 191
ASN A  25
GLY A 196
GLY A  52
None
APR  A 285 ( 4.9A)
None
APR  A 285 (-3.2A)
SO4  A 288 ( 3.4A)
1.21A 3pp7B-1txzA:
undetectable
3pp7B-1txzA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xat XENOBIOTIC
ACETYLTRANSFERASE


(Pseudomonas
aeruginosa)
PF00132
(Hexapep)
5 PRO A 107
GLY A  78
TYR A 105
GLY A 128
ALA A 108
None
1.49A 3pp7B-1xatA:
undetectable
3pp7B-1xatA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2o HYPOTHETICAL PROTEIN
BT3146


(Bacteroides
thetaiotaomicron)
no annotation 5 THR A 237
PRO A  69
GLY A  65
TYR A 185
ALA A  71
None
1.39A 3pp7B-2a2oA:
undetectable
3pp7B-2a2oA:
17.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2e28 PYRUVATE KINASE

(Geobacillus
stearothermophilus)
PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C)
8 THR A  10
PRO A  13
ARG A  33
ASN A  35
HIS A  38
GLY A  39
GLY A 314
ALA A 317
None
0.49A 3pp7B-2e28A:
59.4
3pp7B-2e28A:
38.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egu CYSTEINE SYNTHASE

(Geobacillus
kaustophilus)
PF00291
(PALP)
5 THR A 117
PRO A  71
GLY A  77
GLY A 125
ALA A 126
None
1.33A 3pp7B-2eguA:
3.4
3pp7B-2eguA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hp3 IDS-EPIMERASE

(Agrobacterium
tumefaciens)
PF03972
(MmgE_PrpD)
5 PRO A 397
GLY A 373
TYR A 272
GLY A 280
ALA A 279
None
UNX  A1212 ( 3.6A)
None
None
None
1.40A 3pp7B-2hp3A:
undetectable
3pp7B-2hp3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2isq CYSTEINE SYNTHASE

(Arabidopsis
thaliana)
PF00291
(PALP)
5 THR A 119
PRO A  73
GLY A  76
GLY A 127
ALA A 128
None
1.25A 3pp7B-2isqA:
4.0
3pp7B-2isqA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qed HYDROXYACYLGLUTATHIO
NE HYDROLASE


(Salmonella
enterica)
PF00753
(Lactamase_B)
PF16123
(HAGH_C)
5 THR A  86
PRO A  77
TYR A 117
GLY A  84
ALA A  85
None
1.35A 3pp7B-2qedA:
undetectable
3pp7B-2qedA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ux8 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE


(Sphingomonas
elodea)
PF00483
(NTP_transferase)
5 PRO A  12
HIS A 113
GLY A 112
GLY A  60
ALA A  14
None
1.08A 3pp7B-2ux8A:
4.6
3pp7B-2ux8A:
19.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2vgi PYRUVATE KINASE
ISOZYMES R/L


(Homo sapiens)
PF00224
(PK)
PF02887
(PK_C)
7 THR A  93
ARG A 116
ASN A 118
HIS A 121
GLY A 406
ALA A 409
LYS A 410
None
PGA  A1575 (-3.7A)
K  A1576 (-4.0A)
None
None
None
None
0.77A 3pp7B-2vgiA:
58.5
3pp7B-2vgiA:
47.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2vgi PYRUVATE KINASE
ISOZYMES R/L


(Homo sapiens)
PF00224
(PK)
PF02887
(PK_C)
9 THR A  93
PRO A  96
ARG A 116
ASN A 118
HIS A 121
GLY A 122
TYR A 126
GLY A 406
ALA A 409
None
None
PGA  A1575 (-3.7A)
K  A1576 (-4.0A)
None
None
None
None
None
0.54A 3pp7B-2vgiA:
58.5
3pp7B-2vgiA:
47.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkg E3 UBIQUITIN-PROTEIN
LIGASE UHRF1


(Mus musculus)
PF02182
(SAD_SRA)
5 ASN A 509
GLY A 485
TYR A 483
GLY A 461
ALA A 462
None
1.38A 3pp7B-2zkgA:
undetectable
3pp7B-2zkgA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwv PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE


(Thermus
thermophilus)
PF05175
(MTS)
5 ASN A  53
HIS A  35
GLY A  57
GLY A 139
ALA A 138
None
1.32A 3pp7B-2zwvA:
3.5
3pp7B-2zwvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyi LIPASE, PUTATIVE

(Archaeoglobus
fulgidus)
PF00561
(Abhydrolase_1)
5 THR A  62
PRO A 425
GLY A  79
GLY A  33
ALA A  32
None
None
None
STE  A 500 ( 4.0A)
STE  A 500 (-4.7A)
1.37A 3pp7B-2zyiA:
undetectable
3pp7B-2zyiA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ai7 XYLULOSE-5-PHOSPHATE
/FRUCTOSE-6-PHOSPHAT
E PHOSPHOKETOLASE


(Bifidobacterium
longum)
PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N)
5 THR A  68
GLY A  76
TYR A  28
GLY A  99
ALA A 101
None
1.49A 3pp7B-3ai7A:
undetectable
3pp7B-3ai7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT
MEMBRANE-BOUND
HYDROGENASE SMALL
SUBUNIT


(Hydrogenovibrio
marinus)
PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
5 ARG B  32
ASN A 228
HIS A 221
GLY A 225
GLY A  77
None
1.27A 3pp7B-3ayxB:
undetectable
3pp7B-3ayxB:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b97 ALPHA-ENOLASE

(Homo sapiens)
PF00113
(Enolase_C)
PF03952
(Enolase_N)
5 THR A 204
ASN A 205
GLY A 159
GLY A 200
ALA A 203
None
1.44A 3pp7B-3b97A:
6.6
3pp7B-3b97A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bfg CLASS A
BETA-LACTAMASE SED1


(Citrobacter
sedlakii)
PF13354
(Beta-lactamase2)
5 THR A 159
GLY A  45
TYR A 264
ALA A 185
LYS A 188
None
1.30A 3pp7B-3bfgA:
undetectable
3pp7B-3bfgA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bg9 PYRUVATE
CARBOXYLASE,
MITOCHONDRIAL


(Homo sapiens)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
5 THR A 652
PRO A 909
ASN A 653
GLY A 953
GLY A 650
None
1.47A 3pp7B-3bg9A:
5.8
3pp7B-3bg9A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE


(Rhodobacter
sphaeroides)
PF04952
(AstE_AspA)
5 THR A 160
ASN A 186
HIS A 259
GLY A 182
ALA A 183
None
1.35A 3pp7B-3cdxA:
undetectable
3pp7B-3cdxA:
22.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3eoe PYRUVATE KINASE

(Toxoplasma
gondii)
PF00224
(PK)
PF02887
(PK_C)
8 THR A  43
PRO A  46
ARG A  66
ASN A  68
HIS A  71
GLY A  72
GLY A 348
ALA A 351
None
0.24A 3pp7B-3eoeA:
54.6
3pp7B-3eoeA:
42.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2i ESTERASE

(Xanthomonas
oryzae)
PF03583
(LIP)
5 PRO A 340
ASN A 335
GLY A 332
GLY A 226
ALA A 337
None
1.49A 3pp7B-3h2iA:
4.6
3pp7B-3h2iA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3v PROBABLE SECRETED
SOLUTE-BINDING
LIPOPROTEIN


(Streptomyces
coelicolor)
PF01547
(SBP_bac_1)
5 THR A 295
PRO A 288
ASN A 163
GLY A 293
ALA A 292
None
1.48A 3pp7B-3i3vA:
undetectable
3pp7B-3i3vA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)


(Helicobacter
pylori)
PF00483
(NTP_transferase)
5 PRO A   8
HIS A 110
GLY A 109
GLY A  56
ALA A  10
None
1.12A 3pp7B-3jujA:
4.3
3pp7B-3jujA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kal HOMOGLUTATHIONE
SYNTHETASE


(Glycine max)
PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP)
5 THR A 175
PRO A 324
ARG A 153
ASN A 171
GLY A 332
HGS  A 501 (-4.7A)
None
HGS  A 501 ( 2.8A)
MG  A 502 (-2.9A)
MG  A 504 (-3.8A)
1.43A 3pp7B-3kalA:
undetectable
3pp7B-3kalA:
21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3khd PYRUVATE KINASE

(Plasmodium
falciparum)
PF00224
(PK)
PF02887
(PK_C)
8 THR A  53
PRO A  56
ARG A  76
ASN A  78
HIS A  81
GLY A  82
GLY A 357
ALA A 360
None
0.52A 3pp7B-3khdA:
56.6
3pp7B-3khdA:
43.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l9y SUPEROXIDE DISMUTASE
[CU-ZN]


(Bombyx mori)
PF00080
(Sod_Cu)
5 THR A 137
HIS A  47
GLY A  81
GLY A 141
ALA A 140
None
CU  A 156 (-3.2A)
None
None
None
1.39A 3pp7B-3l9yA:
undetectable
3pp7B-3l9yA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB


(Streptococcus
agalactiae)
PF01071
(GARS_A)
PF04262
(Glu_cys_ligase)
5 THR A 384
PRO A 196
HIS A 336
GLY A 387
ALA A 386
None
1.49A 3pp7B-3ln6A:
undetectable
3pp7B-3ln6A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mh9 LIPOPROTEIN LPRG

(Mycobacterium
tuberculosis)
no annotation 5 THR C 193
GLY C 212
GLY C 170
ALA C 192
LYS C 171
None
1.30A 3pp7B-3mh9C:
undetectable
3pp7B-3mh9C:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mha LIPOPROTEIN LPRG

(Mycobacterium
tuberculosis)
PF07161
(LppX_LprAFG)
5 THR A 193
GLY A 212
GLY A 170
ALA A 192
LYS A 171
None
1.28A 3pp7B-3mhaA:
undetectable
3pp7B-3mhaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mos TRANSKETOLASE

(Homo sapiens)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
5 THR A 511
PRO A 534
GLY A 569
GLY A 509
ALA A 508
None
1.38A 3pp7B-3mosA:
2.4
3pp7B-3mosA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwz BH2602 PROTEIN

(Bacillus
halodurans)
PF03061
(4HBT)
5 ASN A 114
HIS A 116
TYR A 117
GLY A 144
LYS A 145
None
1.44A 3pp7B-3nwzA:
undetectable
3pp7B-3nwzA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyw PUTATIVE
OXIDOREDUCTASE


(Bacteroides
thetaiotaomicron)
PF00106
(adh_short)
5 THR A  27
PRO A  59
ASN A  53
GLY A  29
ALA A  26
None
1.49A 3pp7B-3nywA:
undetectable
3pp7B-3nywA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3p MANNOSYL-3-PHOSPHOGL
YCERATE SYNTHASE


(Rubrobacter
xylanophilus)
PF00535
(Glycos_transf_2)
5 PRO A 206
ARG A 254
GLY A 180
GLY A 209
ALA A 208
None
MG  A 339 ( 4.7A)
None
GDD  A 340 (-3.5A)
None
1.36A 3pp7B-3o3pA:
5.0
3pp7B-3o3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfk UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus)
PF00149
(Metallophos)
PF02872
(5_nucleotid_C)
5 THR A 346
ASN A 459
GLY A 466
TYR A 469
ALA A 347
None
AKG  A 514 ( 4.0A)
None
None
None
1.28A 3pp7B-3qfkA:
5.0
3pp7B-3qfkA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtg PYRUVATE KINASE

(Pyrobaculum
aerophilum)
PF00224
(PK)
PF02887
(PK_C)
6 THR A  22
PRO A  25
ARG A  46
ASN A  48
HIS A  51
ALA A 326
None
0.47A 3pp7B-3qtgA:
45.8
3pp7B-3qtgA:
29.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qv9 PYRUVATE KINASE 2

(Trypanosoma
cruzi)
PF00224
(PK)
PF02887
(PK_C)
8 THR A  27
ARG A  50
ASN A  52
HIS A  55
GLY A  56
GLY A 332
ALA A 335
LYS A 336
PO4  A 501 (-3.5A)
PO4  A 501 (-3.7A)
K  A 500 ( 3.5A)
None
None
PO4  A 501 (-3.6A)
PO4  A 501 (-3.6A)
PO4  A 501 ( 4.9A)
1.24A 3pp7B-3qv9A:
69.2
3pp7B-3qv9A:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qv9 PYRUVATE KINASE 2

(Trypanosoma
cruzi)
PF00224
(PK)
PF02887
(PK_C)
9 THR A  27
PRO A  30
ARG A  50
ASN A  52
GLY A  56
TYR A  60
GLY A 332
ALA A 335
LYS A 336
PO4  A 501 (-3.5A)
None
PO4  A 501 (-3.7A)
K  A 500 ( 3.5A)
None
None
PO4  A 501 (-3.6A)
PO4  A 501 (-3.6A)
PO4  A 501 ( 4.9A)
0.60A 3pp7B-3qv9A:
69.2
3pp7B-3qv9A:
75.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus)
PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C)
8 THR A   9
PRO A  12
ARG A  32
ASN A  34
HIS A  37
GLY A  38
GLY A 312
ALA A 315
None
0.43A 3pp7B-3t05A:
57.6
3pp7B-3t05A:
36.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE


(Sinorhizobium
meliloti)
PF05035
(DGOK)
5 THR A  42
HIS A  55
GLY A  54
GLY A  39
ALA A  43
None
1.47A 3pp7B-3t69A:
2.7
3pp7B-3t69A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tev GLYCOSYL HYROLASE,
FAMILY 3


(Deinococcus
radiodurans)
PF00933
(Glyco_hydro_3)
5 THR A 107
ASN A 111
HIS A 165
GLY A 158
ALA A 160
None
1.30A 3pp7B-3tevA:
6.2
3pp7B-3tevA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE


(Salmonella
enterica)
PF02769
(AIRS_C)
PF13507
(GATase_5)
5 THR A 322
PRO A 328
ASN A 259
GLY A 314
GLY A 325
None
None
ANP  A2001 (-3.7A)
None
None
1.48A 3pp7B-3ummA:
undetectable
3pp7B-3ummA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2


(Enterovirus A)
PF00073
(Rhv)
5 PRO B 152
HIS B 278
TYR B 171
GLY B 282
LYS B 150
None
1.11A 3pp7B-3vboB:
undetectable
3pp7B-3vboB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wcx SPHINGOMYELINASE C

(Streptomyces
griseocarneus)
PF03372
(Exo_endo_phos)
5 THR A  58
ASN A  57
HIS A 191
GLY A 234
ALA A  95
None
SIN  A 402 ( 4.1A)
SIN  A 402 (-4.1A)
None
None
1.41A 3pp7B-3wcxA:
undetectable
3pp7B-3wcxA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE


(Bifidobacterium
longum)
PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C)
5 ARG A 275
ASN A 268
GLY A 235
GLY A 264
ALA A 266
None
1.12A 3pp7B-3wfzA:
10.2
3pp7B-3wfzA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE


(Bifidobacterium
longum)
PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C)
5 THR A 342
PRO A 463
GLY A 472
GLY A 338
ALA A 461
None
1.39A 3pp7B-3wfzA:
10.2
3pp7B-3wfzA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wlx LOW SPECIFICITY
L-THREONINE ALDOLASE


(Escherichia
coli)
no annotation 5 PRO B 100
ASN B  84
GLY B  79
GLY B  91
ALA B  92
None
1.41A 3pp7B-3wlxB:
undetectable
3pp7B-3wlxB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wyh LYSOZYME G

(Struthio
camelus)
PF01464
(SLT)
5 ARG A  35
HIS A 183
GLY A 184
TYR A 185
ALA A  38
None
1.42A 3pp7B-3wyhA:
undetectable
3pp7B-3wyhA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2l TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE/RESPONSE


(Bacteroides
thetaiotaomicron)
PF07494
(Reg_prop)
PF07495
(Y_Y_Y)
5 THR A 501
ASN A 546
GLY A 590
TYR A 636
GLY A 514
None
0.89A 3pp7B-4a2lA:
undetectable
3pp7B-4a2lA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ako SPORE COAT PROTEIN A

(Bacillus
subtilis)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
5 PRO A 414
GLY A 445
TYR A 441
GLY A 376
ALA A 375
None
1.31A 3pp7B-4akoA:
undetectable
3pp7B-4akoA:
22.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4drs PYRUVATE KINASE

(Cryptosporidium
parvum)
PF00224
(PK)
PF02887
(PK_C)
8 THR A  51
PRO A  54
ARG A  74
ASN A  76
HIS A  79
GLY A  80
GLY A 363
ALA A 366
ACT  A 605 ( 4.2A)
None
GOL  A 603 ( 3.6A)
GOL  A 603 ( 3.3A)
ACT  A 606 (-4.0A)
ACT  A 606 (-4.0A)
ACT  A 605 (-3.7A)
ACT  A 605 ( 4.0A)
0.36A 3pp7B-4drsA:
56.3
3pp7B-4drsA:
42.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewg BETA-KETOACYL
SYNTHASE


(Paraburkholderia
phymatum)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
5 PRO A 359
ARG A 220
ASN A 362
GLY A  29
TYR A 332
None
1.41A 3pp7B-4ewgA:
undetectable
3pp7B-4ewgA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjh PHOSPHOMANNOMUTASE

(Brucella
melitensis)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
5 THR A 241
PRO A  85
TYR A 159
GLY A 243
ALA A 245
None
None
None
SEP  A 104 ( 4.6A)
None
1.41A 3pp7B-4hjhA:
4.0
3pp7B-4hjhA:
23.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hyv PYRUVATE KINASE 1

(Trypanosoma
brucei)
PF00224
(PK)
PF02887
(PK_C)
10 THR A  27
PRO A  30
ARG A  50
ASN A  52
HIS A  55
GLY A  56
TYR A  60
GLY A 332
ALA A 335
LYS A 336
None
None
PEP  A1003 (-3.8A)
K  A1002 (-3.3A)
None
None
None
None
None
None
0.48A 3pp7B-4hyvA:
67.4
3pp7B-4hyvA:
74.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH


(Vibrio
parahaemolyticus)
PF02386
(TrkH)
5 THR A 434
PRO A 440
ASN A 437
GLY A 221
ALA A 433
None
None
None
K  A 504 (-3.5A)
None
1.40A 3pp7B-4j9uA:
undetectable
3pp7B-4j9uA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kgb SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE


(Drosophila
melanogaster)
PF01144
(CoA_trans)
5 PRO A 227
ASN A  84
GLY A  56
GLY A 133
ALA A 136
None
1.33A 3pp7B-4kgbA:
undetectable
3pp7B-4kgbA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4law PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4


(Homo sapiens)
PF00254
(FKBP_C)
5 PRO A 201
GLY A 176
TYR A 245
GLY A 228
ALA A 226
None
1.29A 3pp7B-4lawA:
undetectable
3pp7B-4lawA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lz6 BH2163 PROTEIN

(Bacillus
halodurans)
PF01554
(MatE)
5 THR A  57
ASN A 263
GLY A 127
GLY A 276
ALA A  54
None
1.40A 3pp7B-4lz6A:
undetectable
3pp7B-4lz6A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nap EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7


(Desulfovibrio
alaskensis)
PF03480
(DctP)
5 THR A 149
PRO A 152
GLY A 116
GLY A 270
ALA A 120
None
1.31A 3pp7B-4napA:
undetectable
3pp7B-4napA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p48 ANTIBODY SCFV 180

(Gallus gallus)
PF07686
(V-set)
5 PRO A  98
GLY A 233
TYR A 234
GLY A  24
ALA A  92
None
1.14A 3pp7B-4p48A:
undetectable
3pp7B-4p48A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhx UNCHARACTERIZED
PROTEIN


(Bacteroides
caccae)
PF11958
(DUF3472)
PF16871
(DUF5077)
5 HIS A 318
GLY A 164
TYR A 165
GLY A 203
ALA A 194
PEG  A 518 (-4.5A)
None
None
None
None
1.24A 3pp7B-4qhxA:
undetectable
3pp7B-4qhxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2v CYSTEINE SYNTHETASE

(Helicobacter
pylori)
PF00291
(PALP)
5 THR A 118
PRO A  72
GLY A  75
GLY A 126
ALA A 127
None
1.26A 3pp7B-4r2vA:
3.9
3pp7B-4r2vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxt SUGAR ABC
TRANSPORTER


(Agrobacterium
tumefaciens)
PF13407
(Peripla_BP_4)
5 PRO A 172
ARG A 180
GLY A 205
GLY A 175
ALA A 174
None
ARA  A 401 (-3.0A)
None
None
None
1.50A 3pp7B-4rxtA:
3.7
3pp7B-4rxtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca)
PF07993
(NAD_binding_4)
5 ASN A1259
GLY A1310
TYR A1252
GLY A1218
ALA A1257
None
1.32A 3pp7B-4w4tA:
undetectable
3pp7B-4w4tA:
21.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yj5 PYRUVATE KINASE PKM

(Homo sapiens)
PF00224
(PK)
PF02887
(PK_C)
10 THR A  50
PRO A  53
ARG A  73
ASN A  75
HIS A  78
GLY A  79
TYR A  83
GLY A 363
ALA A 366
LYS A 367
None
None
PYR  A 601 ( 4.7A)
MG  A 602 (-3.2A)
None
None
None
None
None
None
0.48A 3pp7B-4yj5A:
49.3
3pp7B-4yj5A:
49.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4za3 RRNA N-GLYCOSIDASE

(Momordica
charantia)
PF00652
(Ricin_B_lectin)
5 THR B 179
ARG B 181
GLY B 208
ALA B 124
LYS B 125
None
1.38A 3pp7B-4za3B:
undetectable
3pp7B-4za3B:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4p UBIQUITIN-CONJUGATIN
G ENZYME E2 Z


(Homo sapiens)
PF00179
(UQ_con)
5 THR A 218
PRO A 179
ASN A 220
HIS A 223
TYR A 240
None
1.42A 3pp7B-5a4pA:
undetectable
3pp7B-5a4pA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7n MTA/SAH NUCLEOSIDASE

(Aeromonas
hydrophila)
PF01048
(PNP_UDP_1)
5 ASN A 200
HIS A 108
GLY A 106
GLY A 127
ALA A 196
None
None
SAH  A 301 (-3.2A)
None
None
1.16A 3pp7B-5b7nA:
2.1
3pp7B-5b7nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7n MTA/SAH NUCLEOSIDASE

(Aeromonas
hydrophila)
PF01048
(PNP_UDP_1)
5 ASN A 200
HIS A 108
GLY A 107
GLY A 127
ALA A 196
None
1.31A 3pp7B-5b7nA:
2.1
3pp7B-5b7nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp8 ENT-COPALYL
DIPHOSPHATE SYNTHASE


(Streptomyces
platensis)
PF00432
(Prenyltrans)
PF13243
(SQHop_cyclase_C)
5 PRO A 263
HIS A 212
GLY A 220
TYR A 246
ALA A 305
None
1.35A 3pp7B-5bp8A:
undetectable
3pp7B-5bp8A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7l CONTACTIN-2

(Mus musculus)
PF00041
(fn3)
5 PRO A 782
ASN A 894
GLY A 844
GLY A 724
ALA A 810
None
1.15A 3pp7B-5e7lA:
undetectable
3pp7B-5e7lA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ek8 LIPOXYGENASE

(Cyanothece sp.
PCC 8801)
PF00305
(Lipoxygenase)
5 PRO A 104
GLY A  88
TYR A 102
GLY A 108
ALA A 107
None
1.48A 3pp7B-5ek8A:
undetectable
3pp7B-5ek8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epg ALDEHYDE OXIDASE

(Homo sapiens)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
5 THR A 932
PRO A 926
GLY A1276
TYR A1215
ALA A 929
None
1.31A 3pp7B-5epgA:
undetectable
3pp7B-5epgA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm8 MYOMESIN-1

(Homo sapiens)
PF00041
(fn3)
5 PRO A 513
ASN A 588
GLY A 543
TYR A 544
ALA A 511
None
1.38A 3pp7B-5fm8A:
undetectable
3pp7B-5fm8A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gk2 KETOSYNTHASE STLD

(Photorhabdus
laumondii)
PF08541
(ACP_syn_III_C)
5 THR A 122
GLY A 198
TYR A 344
GLY A 124
ALA A 128
None
1.32A 3pp7B-5gk2A:
undetectable
3pp7B-5gk2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1f UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE


(Burkholderia
vietnamiensis)
PF00483
(NTP_transferase)
5 PRO A  10
HIS A 113
GLY A 112
GLY A  58
ALA A  12
UPG  A 301 (-4.3A)
None
None
None
UPG  A 301 (-3.2A)
1.13A 3pp7B-5i1fA:
4.6
3pp7B-5i1fA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldf GLUTAMINE SYNTHETASE

(Salmonella
enterica)
PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N)
5 THR A 315
PRO A 363
ASN A 317
GLY A 265
ALA A 364
None
1.02A 3pp7B-5ldfA:
undetectable
3pp7B-5ldfA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thm ESTERASE-6

(Drosophila
melanogaster)
PF00135
(COesterase)
5 PRO A  62
ASN A 119
HIS A 105
GLY A 114
ALA A 115
MLY  A  60 ( 4.3A)
None
None
None
None
1.49A 3pp7B-5thmA:
undetectable
3pp7B-5thmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhs SUGAR TRANSPORTER
SEMISWEET


(Leptospira
biflexa)
PF04193
(PQ-loop)
5 PRO A  59
GLY A   6
TYR A   7
GLY A  52
ALA A  57
None
1.38A 3pp7B-5uhsA:
undetectable
3pp7B-5uhsA:
10.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wrp PYRUVATE KINASE

(Mycobacterium
tuberculosis)
no annotation 7 THR A  10
PRO A  13
ARG A  33
ASN A  35
HIS A  38
GLY A  39
GLY A 311
None
0.57A 3pp7B-5wrpA:
52.5
3pp7B-5wrpA:
36.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE
SUBUNIT ABC10-ALPHA


(Komagataella
phaffii)
PF00562
(RNA_pol_Rpb2_6)
PF03604
(DNA_RNApol_7kD)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
5 THR B 956
PRO L  47
ARG B 107
GLY L  54
GLY B 960
None
1.24A 3pp7B-5xogB:
undetectable
3pp7B-5xogB:
16.79