SIMILAR PATTERNS OF AMINO ACIDS FOR 3P6H_A_IBPA133_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bo6 ESTROGEN
SULFOTRANSFERASE

(Mus musculus) 		PF00685
(Sulfotransfer_1) 		4 PHE A 210
ILE A  43
VAL A  58
TYR A  62
 None
 1.07A 3p6hA-1bo6A:
undetectable		 3p6hA-1bo6A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)

(Rattus
norvegicus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 PHE A 258
ASP A 176
ILE A 209
VAL A 246
 None
 1.02A 3p6hA-1bu8A:
undetectable		 3p6hA-1bu8A:
16.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bwy PROTEIN (HEART FATTY
ACID BINDING
PROTEIN)

(Bos taurus) 		PF00061
(Lipocalin) 		4 PHE A  70
ASP A  77
ILE A  51
VAL A  49
 None
 1.10A 3p6hA-1bwyA:
19.2		 3p6hA-1bwyA:
64.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		4 PHE A  35
ASP A  39
ILE A  47
VAL A 186
 None
 1.07A 3p6hA-1e0tA:
undetectable		 3p6hA-1e0tA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 ASP B 280
ILE B 256
VAL B 269
TYR B 335
 None
 1.05A 3p6hA-1e6vB:
undetectable		 3p6hA-1e6vB:
14.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ftp MUSCLE FATTY ACID
BINDING PROTEIN

(Schistocerca
gregaria) 		PF00061
(Lipocalin) 		5 PHE A  17
MET A  21
ILE A 106
ARG A 128
TYR A 130
 None
 0.83A 3p6hA-1ftpA:
19.9		 3p6hA-1ftpA:
40.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j08 GLUTAREDOXIN-LIKE
PROTEIN

(Pyrococcus
horikoshii) 		PF00085
(Thioredoxin)
PF13192
(Thioredoxin_3) 		4 PHE A 159
MET A 155
ILE A 198
VAL A 136
 None
 1.10A 3p6hA-1j08A:
undetectable		 3p6hA-1j08A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5w GLYCYL-TRNA
SYNTHETASE ALPHA
CHAIN

(Thermotoga
maritima) 		PF02091
(tRNA-synt_2e) 		4 PHE A 139
ILE A  81
VAL A  79
TYR A 159
 None
 1.09A 3p6hA-1j5wA:
undetectable		 3p6hA-1j5wA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 842
VAL A 801
ARG A 713
TYR A 715
 None
 0.75A 3p6hA-1kcwA:
undetectable		 3p6hA-1kcwA:
10.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mdc INSECT FATTY ACID
BINDING PROTEIN

(Manduca sexta) 		PF00061
(Lipocalin) 		4 PHE A  15
VAL A 114
ARG A 127
TYR A 129
 None
PLM  A 133 (-4.8A)
PLM  A 133 (-3.8A)
PLM  A 133 (-4.7A)
 0.76A 3p6hA-1mdcA:
19.0		 3p6hA-1mdcA:
31.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o8v FATTY ACID BINDING
PROTEIN HOMOLOG

(Echinococcus
granulosus) 		PF00061
(Lipocalin) 		6 PHE A  16
MET A  20
ASP A  77
ILE A 105
ARG A 127
TYR A 129
 PLM  A1136 (-4.7A)
PLM  A1136 (-3.5A)
PLM  A1136 (-3.8A)
None
PLM  A1136 (-4.4A)
PLM  A1136 (-4.6A)
 0.58A 3p6hA-1o8vA:
23.7		 3p6hA-1o8vA:
41.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pk0 CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA) 		4 PHE A 469
ASP A 369
ILE A 474
ARG A 472
 None
 1.08A 3p6hA-1pk0A:
undetectable		 3p6hA-1pk0A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN

(Escherichia
coli) 		PF00268
(Ribonuc_red_sm) 		4 PHE A  36
ASP A 257
ILE A  99
VAL A 108
 None
 0.83A 3p6hA-1pm2A:
undetectable		 3p6hA-1pm2A:
15.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pmp P2 MYELIN PROTEIN

(Bos taurus) 		PF00061
(Lipocalin) 		7 PHE A  16
MET A  20
ASP A  76
ILE A 104
VAL A 115
ARG A 126
TYR A 128
 OLA  A 200 ( 4.8A)
OLA  A 200 (-4.6A)
OLA  A 200 ( 4.7A)
None
None
OLA  A 200 (-3.9A)
OLA  A 200 (-4.7A)
 0.59A 3p6hA-1pmpA:
24.3		 3p6hA-1pmpA:
65.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6v SUBTILISIN-LIKE
SERINE PROTEASE

(Fervidobacterium
pennivorans) 		PF00082
(Peptidase_S8) 		4 PHE A  29
ASP A  87
ILE A  42
VAL A  44
 None
 1.00A 3p6hA-1r6vA:
undetectable		 3p6hA-1r6vA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN

(Halothiobacillus
neapolitanus) 		PF00101
(RuBisCO_small) 		4 PHE M 104
ILE M  43
VAL M  88
TYR M 107
 None
 1.09A 3p6hA-1svdM:
undetectable		 3p6hA-1svdM:
14.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tow FATTY ACID-BINDING
PROTEIN, ADIPOCYTE

(Homo sapiens) 		PF00061
(Lipocalin) 		7 PHE A  16
MET A  20
ASP A  76
ILE A 104
VAL A 115
ARG A 126
TYR A 128
 CRZ  A 501 (-4.5A)
CRZ  A 501 ( 3.8A)
CRZ  A 501 (-4.0A)
CRZ  A 501 ( 4.8A)
None
CRZ  A 501 (-3.8A)
CRZ  A 501 (-4.8A)
 0.27A 3p6hA-1towA:
26.2		 3p6hA-1towA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdw NAD+-DEPENDENT
(R)-2-HYDROXYGLUTARA
TE DEHYDROGENASE

(Acidaminococcus
fermentans) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ASP A  63
ILE A  73
VAL A  49
TYR A   6
 None
 1.05A 3p6hA-1xdwA:
undetectable		 3p6hA-1xdwA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9m FLUORESCEIN-SCFV
LIGHT CHAIN

(Homo sapiens) 		PF07686
(V-set) 		4 PHE L  78
MET L  55
ILE L  21
VAL L  19
 None
 0.96A 3p6hA-2a9mL:
undetectable		 3p6hA-2a9mL:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2au3 DNA PRIMASE

(Aquifex
aeolicus) 		PF01807
(zf-CHC2)
PF08275
(Toprim_N)
PF13155
(Toprim_2) 		4 ILE A 189
VAL A 187
ARG A 204
TYR A 127
 None
 0.75A 3p6hA-2au3A:
undetectable		 3p6hA-2au3A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bk0 MAJOR ALLERGEN API G
1

(Apium
graveolens) 		PF00407
(Bet_v_1) 		4 PHE A 120
ILE A  90
VAL A  85
TYR A  83
 None
 0.89A 3p6hA-2bk0A:
2.1		 3p6hA-2bk0A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cmh SPERMIDINE SYNTHASE

(Helicobacter
pylori) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 PHE A 246
MET A 196
ILE A 168
TYR A 237
 None
 1.00A 3p6hA-2cmhA:
undetectable		 3p6hA-2cmhA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cmt PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
E

(Schistosoma
mansoni) 		PF00160
(Pro_isomerase) 		4 PHE A 136
MET A 107
ILE A 121
VAL A 139
 None
 1.04A 3p6hA-2cmtA:
undetectable		 3p6hA-2cmtA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 ASP A 573
ILE A 592
VAL A 597
TYR A 557
 None
 1.06A 3p6hA-2cvtA:
undetectable		 3p6hA-2cvtA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ga8 HYPOTHETICAL 39.9
KDA PROTEIN

(Saccharomyces
cerevisiae) 		PF07728
(AAA_5) 		4 ASP A  16
ILE A 262
VAL A  27
TYR A 293
 None
 1.09A 3p6hA-2ga8A:
undetectable		 3p6hA-2ga8A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqj PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Leishmania
major) 		PF00160
(Pro_isomerase) 		4 PHE A 139
MET A 110
ILE A 124
VAL A 142
 None
 0.98A 3p6hA-2hqjA:
undetectable		 3p6hA-2hqjA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		4 ASP A  52
ILE A 164
VAL A 175
TYR A 179
 MG  A1211 ( 2.9A)
None
None
None
 1.08A 3p6hA-2jcsA:
undetectable		 3p6hA-2jcsA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2joi HYPOTHETICAL PROTEIN
TA0095

(Thermoplasma
acidophilum) 		no annotation 4 ILE A  67
VAL A  78
ARG A  24
TYR A  26
 None
 0.80A 3p6hA-2joiA:
undetectable		 3p6hA-2joiA:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbm TOP7 FOLD PROTEIN
TOP7M13

(synthetic
construct) 		no annotation 4 ILE A  58
VAL A  10
ARG A  44
TYR A  23
 None
 1.10A 3p6hA-2mbmA:
undetectable		 3p6hA-2mbmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nul PEPTIDYLPROLYL
ISOMERASE

(Escherichia
coli) 		PF00160
(Pro_isomerase) 		4 PHE A 123
MET A  85
ILE A 100
VAL A 126
 None
 1.03A 3p6hA-2nulA:
undetectable		 3p6hA-2nulA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4b SIGMA-E FACTOR
REGULATORY PROTEIN
RSEB

(Escherichia
coli) 		PF03888
(MucB_RseB)
PF17188
(MucB_RseB_C) 		4 ILE A 312
VAL A 263
ARG A 252
TYR A 254
 None
 1.09A 3p6hA-2p4bA:
3.2		 3p6hA-2p4bA:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q9s FATTY ACID-BINDING
PROTEIN

(Mus musculus) 		PF00061
(Lipocalin) 		7 PHE A  16
MET A  20
ASP A  76
ILE A 104
VAL A 115
ARG A 126
TYR A 128
 None
EIC  A 601 ( 4.1A)
EIC  A 601 (-3.6A)
EIC  A 601 ( 4.5A)
EIC  A 601 (-4.3A)
EIC  A 601 (-4.5A)
EIC  A 601 (-4.7A)
 0.54A 3p6hA-2q9sA:
25.7		 3p6hA-2q9sA:
81.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x11 EPHRIN-A5

(Homo sapiens) 		PF00812
(Ephrin) 		4 ILE B  58
VAL B 163
ARG B 138
TYR B 140
 None
 1.09A 3p6hA-2x11B:
undetectable		 3p6hA-2x11B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xbd XYLANASE D

(Cellulomonas
fimi) 		PF00553
(CBM_2) 		4 PHE A 263
ILE A 287
VAL A 315
TYR A 267
 None
 0.84A 3p6hA-2xbdA:
undetectable		 3p6hA-2xbdA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsw 72 KDA INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 ILE A 382
VAL A 361
ARG A 379
TYR A 614
 None
 1.06A 3p6hA-2xswA:
undetectable		 3p6hA-2xswA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbk TYPE II DNA
TOPOISOMERASE VI
SUBUNIT A

(Sulfolobus
shibatae) 		PF04406
(TP6A_N) 		4 PHE A 273
ASP A 238
ILE A 231
VAL A 205
 None
 0.96A 3p6hA-2zbkA:
undetectable		 3p6hA-2zbkA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN

(Escherichia
coli) 		PF06751
(EutB) 		4 MET A 394
ILE A 190
VAL A 189
ARG A 160
 None
None
None
2A3  A 602 (-3.0A)
 0.95A 3p6hA-3anyA:
undetectable		 3p6hA-3anyA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cob KINESIN HEAVY
CHAIN-LIKE PROTEIN

(Solanum
tuberosum) 		PF00225
(Kinesin) 		4 ASP A1195
ILE A 912
VAL A 920
TYR A 934
 None
 0.92A 3p6hA-3cobA:
undetectable		 3p6hA-3cobA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY

(Trichormus
variabilis) 		PF08241
(Methyltransf_11) 		4 ASP A 182
ILE A  19
VAL A  22
TYR A  47
 None
 1.06A 3p6hA-3egeA:
undetectable		 3p6hA-3egeA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gon PHOSPHOMEVALONATE
KINASE

(Streptococcus
pneumoniae) 		PF00288
(GHMP_kinases_N) 		4 PHE A  51
MET A  50
ILE A  46
VAL A  55
 ANP  A 500 (-4.7A)
ANP  A 500 (-3.4A)
None
None
 1.08A 3p6hA-3gonA:
undetectable		 3p6hA-3gonA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf7 UNCHARACTERIZED
CBS-DOMAIN PROTEIN

(Klebsiella
pneumoniae) 		PF00571
(CBS) 		4 ASP A 221
ILE A 238
VAL A 254
TYR A 258
 None
AMP  A   1 ( 4.8A)
None
None
 1.06A 3p6hA-3hf7A:
undetectable		 3p6hA-3hf7A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4u MAJOR CAPSID PROTEIN

(Bordetella
virus BPP1) 		no annotation 4 PHE A 276
MET A 259
ILE A 266
VAL A 177
 None
 1.10A 3p6hA-3j4uA:
undetectable		 3p6hA-3j4uA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 PHE B  79
ASP B 124
VAL B 108
ARG B 106
 None
 1.02A 3p6hA-3jrqB:
2.3		 3p6hA-3jrqB:
22.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nr3 PMP2 PROTEIN

(Homo sapiens) 		PF00061
(Lipocalin) 		6 PHE A  17
MET A  21
ASP A  77
ILE A 105
ARG A 127
TYR A 129
 None
PLM  A 901 (-3.7A)
PLM  A 901 (-4.0A)
PLM  A 901 ( 4.5A)
PLM  A 901 (-4.6A)
PLM  A 901 (-4.6A)
 0.51A 3p6hA-3nr3A:
25.3		 3p6hA-3nr3A:
58.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogg BOTULINUM NEUROTOXIN
TYPE D

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 PHE A1060
ASP A1038
ILE A1007
VAL A1005
 None
 0.95A 3p6hA-3oggA:
undetectable		 3p6hA-3oggA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or5 THIOL:DISULFIDE
INTERCHANGE PROTEIN,
THIOREDOXIN FAMILY
PROTEIN

(Chlorobaculum
tepidum) 		PF08534
(Redoxin) 		4 PHE A  91
ASP A  76
ILE A 154
VAL A 143
 None
 0.89A 3p6hA-3or5A:
undetectable		 3p6hA-3or5A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pic CIP2

(Trichoderma
reesei) 		no annotation 4 ASP A 257
ILE A 294
VAL A 274
TYR A 197
 None
 1.06A 3p6hA-3picA:
undetectable		 3p6hA-3picA:
13.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pp6 SODIUM-CALCIUM
EXCHANGER

(Doryteuthis
pealeii) 		PF00061
(Lipocalin) 		4 PHE A  17
MET A  21
ASP A  77
ARG A 126
 None
PAM  A 133 ( 3.9A)
PAM  A 133 (-4.3A)
PAM  A 133 (-3.9A)
 0.44A 3p6hA-3pp6A:
23.1		 3p6hA-3pp6A:
42.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u5u RAUCAFFRICINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 ASP A 142
ILE A  37
VAL A  72
TYR A 481
 None
 1.08A 3p6hA-3u5uA:
undetectable		 3p6hA-3u5uA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpo RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		4 MET A  93
ILE A 155
VAL A 153
TYR A 221
 None
 0.87A 3p6hA-3vpoA:
undetectable		 3p6hA-3vpoA:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wbg FATTY ACID-BINDING
PROTEIN, HEART

(Homo sapiens) 		PF00061
(Lipocalin) 		5 PHE A  16
MET A  20
ASP A  76
ARG A 126
TYR A 128
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.9A)
2AN  A 201 ( 4.9A)
None
 0.51A 3p6hA-3wbgA:
24.8		 3p6hA-3wbgA:
59.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdy BETA-1,3-1,4-GLUCANA
SE

(Paecilomyces
sp.
'thermophila') 		no annotation 4 ILE A 186
VAL A  83
ARG A 292
TYR A 294
 None
 1.07A 3p6hA-3wdyA:
undetectable		 3p6hA-3wdyA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1

(Lupinus luteus) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		4 ILE A 472
VAL A 510
ARG A 483
TYR A 481
 None
 0.73A 3p6hA-3zk4A:
undetectable		 3p6hA-3zk4A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5w COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2) 		4 ASP A 165
ILE A 976
VAL A1364
ARG A 936
 None
 1.02A 3p6hA-4a5wA:
undetectable		 3p6hA-4a5wA:
6.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4a60 FATTY ACID-BINDING
PROTEIN 9 TESTIS
LIPID-BINDING
PROTEIN, TLBP,
TESTIS-TYPE FATTY
ACID-BINDING
PROTEIN, T-FABP

(Homo sapiens) 		PF00061
(Lipocalin) 		6 MET A  21
ASP A  77
ILE A 105
VAL A 116
ARG A 127
TYR A 129
 EDO  A1134 (-4.5A)
EDO  A1134 (-3.7A)
None
None
None
None
 0.56A 3p6hA-4a60A:
24.1		 3p6hA-4a60A:
56.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4a60 FATTY ACID-BINDING
PROTEIN 9 TESTIS
LIPID-BINDING
PROTEIN, TLBP,
TESTIS-TYPE FATTY
ACID-BINDING
PROTEIN, T-FABP

(Homo sapiens) 		PF00061
(Lipocalin) 		5 PHE A  17
MET A  21
ASP A  77
ARG A 127
TYR A 129
 None
EDO  A1134 (-4.5A)
EDO  A1134 (-3.7A)
None
None
 0.83A 3p6hA-4a60A:
24.1		 3p6hA-4a60A:
56.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4as3 PHOSPHORYLCHOLINE
PHOSPHATASE

(Pseudomonas
aeruginosa) 		no annotation 4 MET A 239
ASP A 267
VAL A  98
TYR A  83
 None
CL  A1329 ( 4.0A)
None
None
 1.10A 3p6hA-4as3A:
undetectable		 3p6hA-4as3A:
18.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azn FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Mus musculus) 		PF00061
(Lipocalin) 		5 ASP A  79
ILE A 107
VAL A 118
ARG A 129
TYR A 131
 None
 0.44A 3p6hA-4aznA:
22.6		 3p6hA-4aznA:
47.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azn FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Mus musculus) 		PF00061
(Lipocalin) 		5 MET A  23
ILE A 107
VAL A 118
ARG A 129
TYR A 131
 None
 0.72A 3p6hA-4aznA:
22.6		 3p6hA-4aznA:
47.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azn FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Mus musculus) 		PF00061
(Lipocalin) 		4 PHE A  19
ASP A  79
ARG A 129
TYR A 131
 None
 0.90A 3p6hA-4aznA:
22.6		 3p6hA-4aznA:
47.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4azp FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Mus musculus) 		PF00061
(Lipocalin) 		7 PHE A  19
MET A  23
ASP A  79
ILE A 107
VAL A 118
ARG A 129
TYR A 131
 None
A9M  A1136 (-3.7A)
A9M  A1136 (-4.0A)
A9M  A1136 (-4.4A)
None
A9M  A1136 (-4.3A)
A9M  A1136 (-4.8A)
 0.44A 3p6hA-4azpA:
24.1		 3p6hA-4azpA:
50.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bk1 PROBABLE SALICYLATE
MONOOXYGENASE

(Rhodococcus
jostii) 		PF01494
(FAD_binding_3) 		4 PHE A  79
ILE A 215
VAL A 204
TYR A 105
 None
P3A  A1399 (-4.4A)
None
None
 0.92A 3p6hA-4bk1A:
undetectable		 3p6hA-4bk1A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyn CHEC, INHIBITOR OF
MCP METHYLATION /
FLIN FUSION PROTEIN

(Thermotoga
maritima) 		PF04509
(CheC) 		4 PHE A 188
MET A  41
ILE A  33
VAL A  63
 None
 1.04A 3p6hA-4hynA:
undetectable		 3p6hA-4hynA:
23.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG

(Anguilla
japonica) 		PF00061
(Lipocalin) 		5 PHE A  17
ASP A  81
VAL A 121
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
None
BLR  A 200 (-4.7A)
BLR  A 200 (-3.5A)
None
 0.89A 3p6hA-4i3cA:
22.0		 3p6hA-4i3cA:
45.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Brugia malayi) 		PF00160
(Pro_isomerase) 		4 PHE A 136
MET A 107
ILE A 121
VAL A 139
 None
 1.02A 3p6hA-4jcpA:
undetectable		 3p6hA-4jcpA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjz TRANSLATION
INITIATION FACTOR
IF-2

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF04760
(IF2_N)
PF11987
(IF-2) 		4 PHE A 113
ASP A  91
ILE A  78
VAL A  76
 None
 0.77A 3p6hA-4kjzA:
undetectable		 3p6hA-4kjzA:
15.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nns FATTY ACID-BINDING
PROTEIN, ADIPOCYTE

(Homo sapiens) 		PF00061
(Lipocalin) 		7 PHE A  16
MET A  20
ASP A  76
ILE A 104
VAL A 115
ARG A 126
TYR A 128
 None
75D  A 201 (-3.6A)
75D  A 201 (-4.1A)
75D  A 201 ( 4.4A)
None
75D  A 201 (-3.9A)
None
 0.25A 3p6hA-4nnsA:
27.5		 3p6hA-4nnsA:
90.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pu5 TOXIN-ANTITOXIN
SYSTEM TOXIN HIPA
FAMILY

(Shewanella
oneidensis) 		PF07804
(HipA_C)
PF13657
(Couple_hipA) 		4 PHE A 105
ILE A  60
VAL A  32
TYR A  34
 None
 1.00A 3p6hA-4pu5A:
undetectable		 3p6hA-4pu5A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1d UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 ILE A  52
VAL A 230
ARG A 134
TYR A 234
 None
None
CA  A 601 ( 4.6A)
None
 1.01A 3p6hA-4r1dA:
undetectable		 3p6hA-4r1dA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 PHE A  65
ASP A 159
ILE A 168
TYR A 176
 None
 1.06A 3p6hA-4r4zA:
undetectable		 3p6hA-4r4zA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA

(Bacillus
subtilis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 PHE A   5
MET A   3
ILE A 108
VAL A  96
 None
 0.92A 3p6hA-4tr6A:
undetectable		 3p6hA-4tr6A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7d ATP-DEPENDENT DNA
HELICASE Q1

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 PHE A 424
ILE A 551
VAL A 444
TYR A 418
 None
 0.97A 3p6hA-4u7dA:
undetectable		 3p6hA-4u7dA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uao IMMUNOGLOBULIN R31C2
LIGHT CHAIN

(Rattus
norvegicus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE B  62
MET B  47
ILE B  21
VAL B  19
 None
 0.95A 3p6hA-4uaoB:
undetectable		 3p6hA-4uaoB:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v0n BARDET-BIEDL
SYNDROME 1 PROTEIN

(Chlamydomonas
reinhardtii) 		PF14779
(BBS1) 		4 ILE B 345
VAL B 364
ARG B 372
TYR B 374
 None
 0.92A 3p6hA-4v0nB:
undetectable		 3p6hA-4v0nB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmj GLUCOSE-6-PHOSPHATE
ISOMERASE

(Colias
eurytheme) 		PF00342
(PGI) 		4 ASP A 509
ILE A  94
VAL A 102
TYR A 277
 None
 1.05A 3p6hA-4wmjA:
undetectable		 3p6hA-4wmjA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmh UNCHARACTERIZED
PROTEIN

(Saccharophagus
degradans) 		PF15979
(Glyco_hydro_115) 		4 PHE A 624
ASP A 661
VAL A 592
TYR A 596
 None
 0.86A 3p6hA-4zmhA:
undetectable		 3p6hA-4zmhA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2p SYNTENIN-1

(Rattus
norvegicus) 		PF00595
(PDZ) 		4 PHE A 213
ASP A 253
ILE A 243
VAL A 267
 None
 1.07A 3p6hA-5a2pA:
undetectable		 3p6hA-5a2pA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b29 FATTY ACID-BINDING
PROTEIN, HEART

(Homo sapiens) 		PF00061
(Lipocalin) 		4 MET A  20
ASP A  76
ARG A 126
TYR A 128
 PLM  A 200 ( 4.0A)
PLM  A 200 ( 4.3A)
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.44A 3p6hA-5b29A:
24.3		 3p6hA-5b29A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5bvq FATTY ACID-BINDING
PROTEIN

(Pygoscelis
papua) 		PF00061
(Lipocalin) 		5 PHE A  17
MET A  21
ASP A  77
ARG A 127
TYR A 129
 None
 1.46A 3p6hA-5bvqA:
23.5		 3p6hA-5bvqA:
75.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5bvq FATTY ACID-BINDING
PROTEIN

(Pygoscelis
papua) 		PF00061
(Lipocalin) 		6 PHE A  17
MET A  21
ASP A  77
ILE A 105
VAL A 116
TYR A 129
 None
 0.65A 3p6hA-5bvqA:
23.5		 3p6hA-5bvqA:
75.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5bvt EPIDERMAL FATTY
ACID-BINDING PROTEIN

(Pygoscelis
papua) 		PF00061
(Lipocalin) 		7 PHE A  19
MET A  23
ASP A  79
ILE A 108
VAL A 119
ARG A 130
TYR A 132
 PAM  A 201 ( 4.9A)
PAM  A 201 ( 3.8A)
PAM  A 201 (-4.0A)
PAM  A 201 ( 4.7A)
None
PAM  A 201 ( 4.6A)
None
 0.46A 3p6hA-5bvtA:
24.5		 3p6hA-5bvtA:
52.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxp POSSIBLE XYLAN
DEGRADATION ENZYME
(GLYCOSYL HYDROLASE
FAMILY 30-LIKE
DOMAIN AND RICIN
B-LIKE DOMAIN)

(Clostridium
acetobutylicum) 		PF02055
(Glyco_hydro_30) 		4 PHE A 158
MET A 187
ASP A 143
TYR A 115
 None
 0.94A 3p6hA-5cxpA:
undetectable		 3p6hA-5cxpA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyr RNA-DEPENDENT RNA
POLYMERASE

(Thosea asigna
virus) 		no annotation 4 ASP B 241
ILE B  97
VAL B 104
TYR B 220
 None
 1.00A 3p6hA-5cyrB:
undetectable		 3p6hA-5cyrB:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN

([Candida]
glabrata) 		PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central) 		4 PHE A 877
ILE A 990
VAL A1005
ARG A 986
 None
 1.08A 3p6hA-5d0fA:
undetectable		 3p6hA-5d0fA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftw CHEMOTAXIS PROTEIN
METHYLTRANSFERASE

(Bacillus
subtilis) 		PF01739
(CheR)
PF03705
(CheR_N) 		4 PHE A 181
ILE A 175
VAL A 171
TYR A 144
 None
 1.08A 3p6hA-5ftwA:
undetectable		 3p6hA-5ftwA:
17.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gkb FATTY ACID BINDIN
PROTEIN, ISOFORM B

(Drosophila
melanogaster) 		PF00061
(Lipocalin) 		5 PHE A  16
MET A  20
ILE A 103
ARG A 125
TYR A 127
 None
 0.53A 3p6hA-5gkbA:
20.3		 3p6hA-5gkbA:
47.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hz5 FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Homo sapiens) 		PF00061
(Lipocalin) 		7 PHE A  19
MET A  23
ASP A  79
ILE A 107
VAL A 118
ARG A 129
TYR A 131
 65X  A 203 ( 4.7A)
65X  A 203 ( 3.9A)
65X  A 203 ( 4.2A)
65X  A 203 (-3.9A)
None
65X  A 203 (-3.9A)
None
 0.56A 3p6hA-5hz5A:
23.7		 3p6hA-5hz5A:
51.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ly6 PNEUMOLYSIN

(Streptococcus
pneumoniae) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 ASP B  67
ILE B 237
VAL B 240
TYR B 242
 None
 0.86A 3p6hA-5ly6B:
undetectable		 3p6hA-5ly6B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2n ELONGATOR COMPLEX
PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 ILE A 755
VAL A 773
ARG A 781
TYR A 783
 None
 0.69A 3p6hA-5m2nA:
undetectable		 3p6hA-5m2nA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmx CSPYL1_ABA

(Citrus sinensis) 		no annotation 4 PHE B  81
ASP B 126
VAL B 110
ARG B 108
 None
 1.10A 3p6hA-5mmxB:
undetectable		 3p6hA-5mmxB:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus) 		no annotation 4 ILE A 836
VAL A 795
ARG A 707
TYR A 709
 None
 0.66A 3p6hA-5n4lA:
undetectable		 3p6hA-5n4lA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6y NITROGENASE
VANADIUM-IRON
PROTEIN BETA CHAIN

(Azotobacter
vinelandii) 		no annotation 4 ILE E  43
VAL E 108
ARG E 107
TYR E 145
 None
 1.01A 3p6hA-5n6yE:
undetectable		 3p6hA-5n6yE:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot1 PULLULANASE TYPE II,
GH13 FAMILY

(Thermococcus
kodakarensis) 		no annotation 4 PHE A 707
MET A 705
ILE A 761
VAL A 715
 None
 1.00A 3p6hA-5ot1A:
undetectable		 3p6hA-5ot1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3b GLYCOSIDE HYDROLASE

(Bacteroides
plebeius) 		no annotation 4 PHE A 457
ILE A 446
VAL A 450
TYR A 100
 None
 1.11A 3p6hA-5t3bA:
undetectable		 3p6hA-5t3bA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u04 ZIKA VIRUS NS5 RDRP

(Zika virus) 		PF00972
(Flavi_NS5) 		4 ASP A 788
ILE A 876
VAL A 872
ARG A 873
 None
 1.10A 3p6hA-5u04A:
undetectable		 3p6hA-5u04A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgr ATLASTIN-3

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 ASP A 233
ILE A 253
VAL A 249
ARG A 250
 None
 1.10A 3p6hA-5vgrA:
undetectable		 3p6hA-5vgrA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wuq ANTI-SIGMA-W FACTOR
RSIW
ECF RNA POLYMERASE
SIGMA FACTOR SIGW

(Bacillus
subtilis) 		PF04542
(Sigma70_r2)
PF08281
(Sigma70_r4_2)
PF13490
(zf-HC2) 		4 ASP C  16
ILE A 145
VAL C  51
ARG C  52
 None
 1.10A 3p6hA-5wuqC:
undetectable		 3p6hA-5wuqC:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xs5 GENOME POLYPROTEIN

(Enterovirus A) 		PF00073
(Rhv) 		4 PHE B 214
MET B 197
ILE B 240
VAL B  85
 None
 1.06A 3p6hA-5xs5B:
undetectable		 3p6hA-5xs5B:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 PHE A 729
ILE A 717
VAL A 681
TYR A 659
 None
 1.06A 3p6hA-5xxoA:
undetectable		 3p6hA-5xxoA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 5
X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 6

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 PHE B 426
ASP A 505
ILE B 392
TYR B 421
 None
 1.08A 3p6hA-5y3rB:
undetectable		 3p6hA-5y3rB:
12.27