SIMILAR PATTERNS OF AMINO ACIDS FOR 3P5N_A_RBFA190_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 5 | THR A 321ASP A 316GLY A 352ALA A 355ALA A 359 | None | 0.90A | 3p5nA-13pkA:0.5 | 3p5nA-13pkA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b3n | PROTEIN (KETOACYLACYL CARRIER PROTEINSYNTHASE 2) (Escherichiacoli) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | THR A 320GLY A 276ALA A 279ALA A 282ASN A 396 | None | 1.17A | 3p5nA-1b3nA:0.0 | 3p5nA-1b3nA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cid | T CELL SURFACEGLYCOPROTEIN CD4 (Rattusnorvegicus) |
PF05790(C2-set)PF09191(CD4-extracel) | 5 | LEU A 74THR A 73ALA A 13ALA A 5LEU A 104 | None | 1.07A | 3p5nA-1cidA:undetectable | 3p5nA-1cidA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eyy | ALDEHYDEDEHYDROGENASE (Vibrio harveyi) |
PF00171(Aldedh) | 5 | LEU A 100GLY A 157ALA A 160ALA A 164LEU A 58 | None | 1.12A | 3p5nA-1eyyA:0.0 | 3p5nA-1eyyA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpe | PROTEIN (GLUCOSEOXIDASE) (Penicilliumamagasakiense) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | THR A 334GLY A 467ALA A 471ALA A 475LEU A 417 | None | 1.09A | 3p5nA-1gpeA:0.0 | 3p5nA-1gpeA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i41 | CYSTATHIONINEGAMMA-SYNTHASE (Nicotianatabacum) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 133THR A 132GLY A 272ALA A 141LEU A 295 | None | 1.17A | 3p5nA-1i41A:0.5 | 3p5nA-1i41A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krq | FERRITIN (Campylobacterjejuni) |
PF00210(Ferritin) | 5 | LEU A 163ASP A 155GLY A 38ALA A 41ALA A 45 | None | 1.00A | 3p5nA-1krqA:2.1 | 3p5nA-1krqA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p15 | PROTEIN-TYROSINEPHOSPHATASE ALPHA (Mus musculus) |
PF00102(Y_phosphatase) | 5 | GLY A 732ALA A 728ALA A 726LEU A 759ASN A 582 | None | 1.12A | 3p5nA-1p15A:1.5 | 3p5nA-1p15A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1php | 3-PHOSPHOGLYCERATEKINASE (Geobacillusstearothermophilus) |
PF00162(PGK) | 5 | THR A 299ASP A 294GLY A 330ALA A 333ALA A 337 | None | 0.81A | 3p5nA-1phpA:0.0 | 3p5nA-1phpA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qap | QUINOLINIC ACIDPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | LEU A 155THR A 154ALA A 161ALA A 165LEU A 127 | None | 1.17A | 3p5nA-1qapA:1.4 | 3p5nA-1qapA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r66 | TDP-GLUCOSE-4,6-DEHYDRATASE (Streptomycesvenezuelae) |
PF16363(GDP_Man_Dehyd) | 5 | LEU A 39THR A 40GLY A 7LEU A 48LEU A 36 | NoneNAD A 900 (-3.3A)NAD A 900 ( 3.7A)NoneNone | 1.10A | 3p5nA-1r66A:undetectable | 3p5nA-1r66A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU B 32GLY B 359ALA B 358LEU B 216ASN B 14 | None | 1.18A | 3p5nA-1tqyB:undetectable | 3p5nA-1tqyB:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcg | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Thermusthermophilus) |
PF01070(FMN_dh) | 5 | LEU A 33GLY A 327ALA A 319LEU A 314LEU A 277 | None | 1.15A | 3p5nA-1vcgA:undetectable | 3p5nA-1vcgA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcg | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Thermusthermophilus) |
PF01070(FMN_dh) | 5 | LEU A 33GLY A 327ALA A 325LEU A 314LEU A 277 | None | 1.11A | 3p5nA-1vcgA:undetectable | 3p5nA-1vcgA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vel | STARVATION-INDUCEDDNA PROTECTINGPROTEIN (Mycolicibacteriumsmegmatis) |
PF00210(Ferritin) | 5 | GLY A 63ALA A 65ALA A 69LEU A 25ASN A 29 | None | 1.13A | 3p5nA-1velA:undetectable | 3p5nA-1velA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ws6 | METHYLTRANSFERASE (Thermusthermophilus) |
PF03602(Cons_hypoth95) | 5 | LEU A 28GLY A 25ALA A 23LEU A 102LEU A 19 | None | 1.15A | 3p5nA-1ws6A:undetectable | 3p5nA-1ws6A:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bxy | MALTOOLIGOSYLTREHALOSE TREHALOHYDROLASE (Deinococcusradiodurans) |
PF00128(Alpha-amylase)PF02922(CBM_48)PF11941(DUF3459) | 5 | LEU A 430THR A 431GLY A 424ALA A 425LEU A 513 | None | 1.19A | 3p5nA-2bxyA:undetectable | 3p5nA-2bxyA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czq | CUTINASE-LIKEPROTEIN (Cryptococcussp. S-2) |
PF01083(Cutinase) | 5 | THR A 191ALA A 197LEU A 11LEU A 158ASN A 31 | None | 0.99A | 3p5nA-2czqA:undetectable | 3p5nA-2czqA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4v | ISOCITRATEDEHYDROGENASE (Acidithiobacillusthiooxidans) |
PF00180(Iso_dh) | 5 | THR A 418ASP A 405GLY A 404ALA A 415LEU A 406 | NoneNAD A2001 (-3.7A)NoneNoneNone | 1.12A | 3p5nA-2d4vA:undetectable | 3p5nA-2d4vA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g17 | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Salmonellaenterica) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | LEU A 5THR A 4ALA A 9ALA A 79LEU A 58 | None | 1.17A | 3p5nA-2g17A:undetectable | 3p5nA-2g17A:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i7p | PANTOTHENATE KINASE3 (Homo sapiens) |
PF03630(Fumble) | 5 | GLY A 302ALA A 305ALA A 309LEU A 186LEU A 334 | None | 1.15A | 3p5nA-2i7pA:undetectable | 3p5nA-2i7pA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ie8 | PHOSPHOGLYCERATEKINASE (Thermuscaldophilus) |
PF00162(PGK) | 5 | THR A 296ASP A 291GLY A 327ALA A 330ALA A 334 | None | 0.77A | 3p5nA-2ie8A:undetectable | 3p5nA-2ie8A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ja2 | GLUTAMYL-TRNASYNTHETASE (Mycobacteriumtuberculosis) |
PF00749(tRNA-synt_1c) | 5 | LEU A 417THR A 418ALA A 412ALA A 435LEU A 436 | None | 1.04A | 3p5nA-2ja2A:undetectable | 3p5nA-2ja2A:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jac | GLUTAREDOXIN-1 (Saccharomycescerevisiae) |
PF00462(Glutaredoxin) | 5 | ASP A 89GLY A 87ALA A 22LEU A 66ASN A 70 | GSH A1000 (-3.2A)GSH A1000 (-3.5A)NoneNoneNone | 1.05A | 3p5nA-2jacA:undetectable | 3p5nA-2jacA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh9 | VP4 CORE PROTEIN (Bluetonguevirus) |
PF05059(Orbi_VP4) | 5 | LEU A 475ASP A 469GLY A 470ALA A 120LEU A 489 | None | 1.16A | 3p5nA-2jh9A:undetectable | 3p5nA-2jh9A:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2py6 | METHYLTRANSFERASEFKBM (Methylobacillusflagellatus) |
PF05050(Methyltransf_21) | 5 | LEU A 189THR A 188ASP A 182GLY A 392ALA A 368 | None | 1.13A | 3p5nA-2py6A:undetectable | 3p5nA-2py6A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | LEU A1142ALA A1095ALA A1099LEU A 798LEU A1073 | None | 1.14A | 3p5nA-2vdcA:undetectable | 3p5nA-2vdcA:8.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vos | FOLYLPOLYGLUTAMATESYNTHASE PROTEINFOLC (Mycobacteriumtuberculosis) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | ASP A 210GLY A 213ALA A 215ALA A 219LEU A 247 | None | 1.15A | 3p5nA-2vosA:undetectable | 3p5nA-2vosA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 5 | THR A1697GLY A1681ALA A1684ALA A1688LEU A1659 | None | 1.08A | 3p5nA-2vz9A:undetectable | 3p5nA-2vz9A:6.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy0 | ANGIOTENSINOGEN (Mus musculus) |
PF00079(Serpin) | 5 | GLY C 389ALA C 376LEU C 378LEU C 244ASN C 385 | None | 1.16A | 3p5nA-2wy0C:undetectable | 3p5nA-2wy0C:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsj | SULFUR RELAYPROTEIN,TUSE/DSRC/DSVCFAMILY (Desulfomicrobiumnorvegicum) |
PF04358(DsrC) | 5 | LEU C 69GLY C 87ALA C 92ALA C 96LEU C 50 | None | 1.15A | 3p5nA-2xsjC:undetectable | 3p5nA-2xsjC:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsj | SULFUR RELAYPROTEIN,TUSE/DSRC/DSVCFAMILY (Desulfomicrobiumnorvegicum) |
PF04358(DsrC) | 5 | LEU C 69GLY C 89ALA C 92ALA C 96LEU C 50 | None | 1.14A | 3p5nA-2xsjC:undetectable | 3p5nA-2xsjC:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3u | MENAQUINONEBIOSYNTHETIC ENZYME (Thermusthermophilus) |
PF02621(VitK2_biosynth) | 5 | ASP A 161GLY A 82ALA A 76LEU A 84ASN A 13 | NoneNoneTLA A 401 ( 4.8A)NoneNone | 1.17A | 3p5nA-3a3uA:undetectable | 3p5nA-3a3uA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 BETACHAIN (Escherichiacoli) |
PF13247(Fer4_11)PF14711(Nitr_red_bet_C) | 5 | LEU B 74GLY B 65ALA B 191ALA B 194ASN B 189 | NoneNoneSF4 B 804 (-4.3A)NoneNone | 1.14A | 3p5nA-3egwB:undetectable | 3p5nA-3egwB:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | LEU A 330GLY A 499ALA A 502ALA A 505LEU A 511 | NoneXCC A 800 ( 4.1A)NoneNoneNone | 1.09A | 3p5nA-3i04A:undetectable | 3p5nA-3i04A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i47 | ENOYL COAHYDRATASE/ISOMERASE(CROTONASE) (Legionellapneumophila) |
PF00378(ECH_1) | 5 | LEU A 162GLY A 112ALA A 115ALA A 119LEU A 179 | None | 0.98A | 3p5nA-3i47A:undetectable | 3p5nA-3i47A:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihv | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 6 | LEU A 417GLY A 218ALA A 220ALA A 144LEU A 192LEU A 252 | None | 1.35A | 3p5nA-3ihvA:undetectable | 3p5nA-3ihvA:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3imk | PUTATIVE MOLYBDENUMCARRIER PROTEIN (Syntrophusaciditrophicus) |
PF12694(MoCo_carrier) | 5 | LEU A 77THR A 76GLY A 135ALA A 18ALA A 22 | NoneNoneGOL A 158 (-4.1A)NoneNone | 0.90A | 3p5nA-3imkA:undetectable | 3p5nA-3imkA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j09 | COPPER-EXPORTINGP-TYPE ATPASE A (Archaeoglobusfulgidus) |
PF00122(E1-E2_ATPase)PF00403(HMA)PF00702(Hydrolase) | 5 | GLY A 385ALA A 387ALA A 391LEU A 723ASN A 675 | None | 1.01A | 3p5nA-3j09A:undetectable | 3p5nA-3j09A:14.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j1e | CHAPERONIN BETASUBUNIT (Acidianustengchongensis) |
PF00118(Cpn60_TCP1) | 6 | LEU A 524THR A 521GLY A 134ALA A 443ALA A 446LEU A 121 | None | 1.38A | 3p5nA-3j1eA:undetectable | 3p5nA-3j1eA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2q | PYROPHOSPHATE-DEPENDENTPHOSPHOFRUCTOKINASE (Marinobacterhydrocarbonoclasticus) |
PF00365(PFK) | 5 | GLY A 74ALA A 75ALA A 403LEU A 405ASN A 407 | None | 1.18A | 3p5nA-3k2qA:undetectable | 3p5nA-3k2qA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o04 | BETA-KETO-ACYLCARRIER PROTEINSYNTHASE II (Listeriamonocytogenes) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | THR A 320GLY A 276ALA A 279ALA A 282ASN A 395 | None | 1.17A | 3p5nA-3o04A:undetectable | 3p5nA-3o04A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o1h | PERIPLASMIC PROTEINTORT (Vibrioparahaemolyticus) |
PF00532(Peripla_BP_1) | 5 | LEU B 210GLY B 225ALA B 229ALA B 232LEU B 168 | None | 1.16A | 3p5nA-3o1hB:undetectable | 3p5nA-3o1hB:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdk | RIBULOKINASE (Bacillushalodurans) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | LEU A 393ASP A 384GLY A 425ALA A 428ALA A 432 | None | 0.59A | 3p5nA-3qdkA:undetectable | 3p5nA-3qdkA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tos | CALS11 (Micromonosporaechinospora) |
PF05711(TylF) | 5 | LEU A 190ASP A 119GLY A 225ALA A 229LEU A 200 | SAH A 258 (-4.2A)NoneNoneNoneNone | 1.18A | 3p5nA-3tosA:undetectable | 3p5nA-3tosA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqh | QUINONEOXIDOREDUCTASE (Coxiellaburnetii) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | THR A 179GLY A 163ALA A 166ALA A 170LEU A 142 | None | 0.91A | 3p5nA-3tqhA:undetectable | 3p5nA-3tqhA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4g | NAMN:DMBPHOSPHORIBOSYLTRANSFERASE (Pyrococcushorikoshii) |
no annotation | 5 | LEU A 12THR A 142GLY A 139ALA A 66LEU A 44 | None | 1.11A | 3p5nA-3u4gA:undetectable | 3p5nA-3u4gA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9i | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,C-TERMINAL DOMAINPROTEIN (Roseiflexus sp.RS-1) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 12THR A 13GLY A 50ALA A 111ALA A 107 | None | 1.13A | 3p5nA-3u9iA:undetectable | 3p5nA-3u9iA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uhj | PROBABLE GLYCEROLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00465(Fe-ADH) | 5 | LEU A 234ALA A 241LEU A 187ASN A 261LEU A 264 | None | 1.18A | 3p5nA-3uhjA:undetectable | 3p5nA-3uhjA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uwd | PHOSPHOGLYCERATEKINASE (Bacillusanthracis) |
PF00162(PGK) | 5 | THR A 299ASP A 294GLY A 330ALA A 333ALA A 337 | None | 0.82A | 3p5nA-3uwdA:undetectable | 3p5nA-3uwdA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4c | ALDEHYDEDEHYDROGENASE(NADP+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | LEU A 110GLY A 167ALA A 170ALA A 174LEU A 68 | None | 1.14A | 3p5nA-3v4cA:undetectable | 3p5nA-3v4cA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8h | THYMIDYLATE SYNTHASE (Burkholderiathailandensis) |
PF00303(Thymidylat_synt) | 5 | GLY A 229ALA A 227ALA A 44LEU A 50LEU A 59 | None | 1.10A | 3p5nA-3v8hA:undetectable | 3p5nA-3v8hA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vtx | MAMA (CandidatusMagnetobacteriumbavaricum) |
PF00515(TPR_1)PF13174(TPR_6)PF13181(TPR_8)PF13414(TPR_11) | 5 | LEU A 84THR A 87ASP A 52GLY A 51ALA A 66 | None | 1.12A | 3p5nA-3vtxA:undetectable | 3p5nA-3vtxA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zid | TUBULIN/FTSZ, GTPASE (Methanothrixthermoacetophila) |
PF00091(Tubulin) | 5 | LEU A 173GLY A 327ALA A 325LEU A 229LEU A 331 | None | 1.01A | 3p5nA-3zidA:undetectable | 3p5nA-3zidA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zvt | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Actinomadurasp. R39) |
PF02113(Peptidase_S13) | 5 | ASP A 345GLY A 348ALA A 48ALA A 419ASN A 438 | NoneB07 A 500 (-4.7A)B07 A 500 (-3.8A)NoneNone | 1.10A | 3p5nA-3zvtA:undetectable | 3p5nA-3zvtA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aby | DNA REPAIR PROTEINRECN (Deinococcusradiodurans) |
PF02463(SMC_N) | 5 | GLY A 98ALA A 111ALA A 123LEU A 135LEU A 34 | None | 1.17A | 3p5nA-4abyA:undetectable | 3p5nA-4abyA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc5 | XYLULOSE KINASE (Homo sapiens) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | LEU A 305THR A 304ALA A 332LEU A 426LEU A 290 | None | 1.13A | 3p5nA-4bc5A:undetectable | 3p5nA-4bc5A:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bev | COPPER EFFLUX ATPASE (Legionellapneumophila) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 5 | LEU A 656THR A 655GLY A 623ALA A 622ALA A 620 | None | 1.10A | 3p5nA-4bevA:undetectable | 3p5nA-4bevA:13.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c6o | CAD PROTEIN (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | LEU A1474GLY A1526ALA A1523ALA A1519LEU A1533 | None | 0.91A | 3p5nA-4c6oA:undetectable | 3p5nA-4c6oA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gic | HISTIDINOLDEHYDROGENASE (Methylococcuscapsulatus) |
PF00815(Histidinol_dh) | 5 | LEU A 56THR A 57GLY A 194ALA A 195ALA A 199 | None | 1.15A | 3p5nA-4gicA:undetectable | 3p5nA-4gicA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lzl | RESPONSE REGULATOR (Streptococcuspneumoniae) |
PF00072(Response_reg) | 5 | ASP A 58GLY A 35ALA A 38ALA A 42LEU A 6 | None | 1.01A | 3p5nA-4lzlA:undetectable | 3p5nA-4lzlA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4me2 | UNCHARACTERIZEDPROTEIN (Brachypodiumdistachyon) |
no annotation | 5 | LEU A 80ALA A 104ALA A 73LEU A 56LEU A 86 | None | 1.13A | 3p5nA-4me2A:undetectable | 3p5nA-4me2A:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n49 | CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF01728(FtsJ) | 5 | THR A 301GLY A 365ALA A 363LEU A 361LEU A 383 | SAM A 601 (-4.1A)SAM A 601 ( 4.0A)NoneNoneSAM A 601 (-4.6A) | 1.17A | 3p5nA-4n49A:undetectable | 3p5nA-4n49A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng4 | PHOSPHOGLYCERATEKINASE (Coxiellaburnetii) |
PF00162(PGK) | 5 | THR A 298ASP A 293GLY A 329ALA A 332ALA A 336 | None MG A 401 (-2.9A) MG A 401 ( 4.0A)NoneNone | 0.88A | 3p5nA-4ng4A:undetectable | 3p5nA-4ng4A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opf | NRPS/PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU A6198GLY A6340ALA A6451ALA A6277LEU A6303 | None | 1.07A | 3p5nA-4opfA:undetectable | 3p5nA-4opfA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0d | TRYPSIN-RESISTANTSURFACE T6 PROTEIN (Streptococcuspyogenes) |
PF16569(GramPos_pilinBB) | 5 | THR A 157GLY A 60ALA A 124ALA A 147LEU A 167 | None | 1.15A | 3p5nA-4p0dA:undetectable | 3p5nA-4p0dA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj1 | 60 KDA HEAT SHOCKPROTEIN,MITOCHONDRIAL (Homo sapiens) |
PF00118(Cpn60_TCP1) | 5 | LEU A 262THR A 261ALA A 236ALA A 240LEU A 247 | None | 1.18A | 3p5nA-4pj1A:undetectable | 3p5nA-4pj1A:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pyr | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Chromobacteriumviolaceum) |
PF04348(LppC) | 5 | LEU A 275THR A 276GLY A 254ALA A 256ALA A 258 | None | 1.12A | 3p5nA-4pyrA:undetectable | 3p5nA-4pyrA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 6 | LEU B 526THR B 523GLY B 136ALA B 445ALA B 448LEU B 123 | None | 1.36A | 3p5nA-4xcgB:2.7 | 3p5nA-4xcgB:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | THR B 519GLY B 136ALA B 445ALA B 448LEU B 123 | None | 1.12A | 3p5nA-4xcgB:2.7 | 3p5nA-4xcgB:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xci | THERMOSOME SUBUNITALPHA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 6 | LEU A 522THR A 519GLY A 123ALA A 441ALA A 444LEU A 110 | None | 1.30A | 3p5nA-4xciA:undetectable | 3p5nA-4xciA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xxl | CYTOCHROME C CLASS I (Sideroxydanslithotrophicus) |
PF00034(Cytochrom_C) | 5 | GLY A 100ALA A 102ALA A 106LEU A 37ASN A 41 | None | 1.10A | 3p5nA-4xxlA:undetectable | 3p5nA-4xxlA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9r | OMEGA-3POLYUNSATURATEDFATTY ACID SYNTHASESUBUNIT PFAD (Shewanellaoneidensis) |
PF03060(NMO) | 5 | GLY A 85ALA A 519ALA A 522LEU A 322ASN A 326 | None | 1.09A | 3p5nA-4z9rA:undetectable | 3p5nA-4z9rA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zi6 | CYTOSOLAMINOPEPTIDASE (Helicobacterpylori) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 5 | LEU A 70GLY A 61ALA A 60ALA A 77LEU A 20 | None | 1.12A | 3p5nA-4zi6A:undetectable | 3p5nA-4zi6A:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bt8 | PHOSPHOGLYCERATEKINASE (Acinetobacterbaumannii) |
PF00162(PGK) | 5 | THR A 300ASP A 295GLY A 331ALA A 334ALA A 338 | None | 0.94A | 3p5nA-5bt8A:undetectable | 3p5nA-5bt8A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ck0 | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | THR A 215GLY A 286ALA A 282ALA A 278LEU A 508 | None | 1.07A | 3p5nA-5ck0A:1.4 | 3p5nA-5ck0A:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5co8 | NUCLEASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00752(XPG_N)PF00867(XPG_I) | 5 | LYS A 8GLY A 209ALA A 213ALA A 217LEU A 191 | None | 1.05A | 3p5nA-5co8A:undetectable | 3p5nA-5co8A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed4 | RESPONSE REGULATOR (Mycobacteriumtuberculosis) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 5 | LEU A 70GLY A 53ALA A 56ALA A 60LEU A 24 | NoneEDO A 303 (-3.7A)NoneNoneNone | 1.13A | 3p5nA-5ed4A:undetectable | 3p5nA-5ed4A:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i32 | AQUAPORIN TIP2-1 (Arabidopsisthaliana) |
PF00230(MIP) | 5 | LEU A 45THR A 46ASP A 52GLY A 55ALA A 58 | None | 1.14A | 3p5nA-5i32A:2.5 | 3p5nA-5i32A:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k6z | PROTEINSIDEKICK-2,PROTEINSIDEKICK-1 CHIMERA (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 5 | LEU A 148THR A 147ALA A 110LEU A 181LEU A 151 | None | 0.94A | 3p5nA-5k6zA:undetectable | 3p5nA-5k6zA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k70 | PROTEIN SIDEKICK-2 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 5 | LEU A 148THR A 147ALA A 110LEU A 181LEU A 151 | None | 0.91A | 3p5nA-5k70A:undetectable | 3p5nA-5k70A:18.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5kbw | RIBOFLAVINTRANSPORTER RIBU (Thermotogamaritima) |
PF12822(ECF_trnsprt) | 6 | LEU A 34ASP A 73GLY A 76ASN A 123ASN A 149LYS A 152 | RBF A 201 (-4.9A)RBF A 201 (-4.0A)RBF A 201 (-2.9A)RBF A 201 (-2.1A)RBF A 201 (-1.8A)RBF A 201 (-3.7A) | 0.87A | 3p5nA-5kbwA:24.2 | 3p5nA-5kbwA:33.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5kbw | RIBOFLAVINTRANSPORTER RIBU (Thermotogamaritima) |
PF12822(ECF_trnsprt) | 6 | LEU A 34ASP A 73GLY A 76LEU A 83ASN A 149LYS A 152 | RBF A 201 (-4.9A)RBF A 201 (-4.0A)RBF A 201 (-2.9A)RBF A 201 (-4.5A)RBF A 201 (-1.8A)RBF A 201 (-3.7A) | 1.38A | 3p5nA-5kbwA:24.2 | 3p5nA-5kbwA:33.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lal | DIRIGENT PROTEIN 6 (Arabidopsisthaliana) |
PF03018(Dirigent) | 5 | LEU A 120THR A 119GLY A 129ALA A 158LEU A 183 | NoneNoneNoneEDO A 211 (-3.9A)None | 1.16A | 3p5nA-5lalA:undetectable | 3p5nA-5lalA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n57 | SUPEROXIDE DISMUTASE (Staphylococcusaureus) |
no annotation | 5 | LEU A 150THR A 151GLY A 76LEU A 159LEU A 53 | None | 1.18A | 3p5nA-5n57A:undetectable | 3p5nA-5n57A:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swn | FLUOROACETATEDEHALOGENASE (Rhodopseudomonaspalustris) |
PF00561(Abhydrolase_1) | 5 | LEU A 4ASP A 64GLY A 69ALA A 205ALA A 207 | None | 1.18A | 3p5nA-5swnA:undetectable | 3p5nA-5swnA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t6o | POLY-BETA-HYDROXYBUTERATE POLYMERASE (Cupriavidusnecator) |
PF07167(PhaC_N) | 5 | GLY A 427ALA A 429ALA A 589LEU A 390ASN A 400 | None | 1.18A | 3p5nA-5t6oA:undetectable | 3p5nA-5t6oA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t6o | POLY-BETA-HYDROXYBUTERATE POLYMERASE (Cupriavidusnecator) |
PF07167(PhaC_N) | 5 | LEU A 329THR A 327GLY A 322LEU A 241LEU A 345 | None | 1.12A | 3p5nA-5t6oA:undetectable | 3p5nA-5t6oA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti1 | FUMARYLACETOACETATEHYDROLASE (Paraburkholderiaxenovorans) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 115THR A 114GLY A 67ALA A 66LEU A 69 | None | 1.06A | 3p5nA-5ti1A:undetectable | 3p5nA-5ti1A:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr1 | CHLORIDE CHANNELPROTEIN (Bos taurus) |
PF00654(Voltage_CLC) | 5 | THR A 492GLY A 465ALA A 467ALA A 434LEU A 361 | None | 1.09A | 3p5nA-5tr1A:undetectable | 3p5nA-5tr1A:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5twb | FERREDOXIN--NADPREDUCTASE (Staphylococcusaureus) |
PF07992(Pyr_redox_2) | 5 | THR A 66GLY A 13ALA A 16ALA A 304LEU A 29 | None | 1.15A | 3p5nA-5twbA:undetectable | 3p5nA-5twbA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 5 | THR A 271GLY A 102ALA A 105ALA A 109LEU A 297 | None | 1.10A | 3p5nA-5uldA:undetectable | 3p5nA-5uldA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfa | RESPONSE REGULATOR (Streptococcuspneumoniae) |
no annotation | 5 | ASP A 58GLY A 35ALA A 38ALA A 42LEU A 6 | None | 1.02A | 3p5nA-5vfaA:undetectable | 3p5nA-5vfaA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgj | PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT ALPHAISOFORM (Homo sapiens) |
no annotation | 5 | THR A 908ALA A 902ALA A 987LEU A 831LEU A 929 | None | 1.16A | 3p5nA-5xgjA:undetectable | 3p5nA-5xgjA:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y58 | ATP-DEPENDENT DNAHELICASE II SUBUNIT2 (Saccharomycescerevisiae) |
no annotation | 5 | LEU B 431THR B 432ALA B 394ALA B 396LEU B 344 | None | 1.18A | 3p5nA-5y58B:undetectable | 3p5nA-5y58B:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysm | CYTOCHROME P450 (Amycolatopsismediterranei) |
no annotation | 5 | LEU A 383GLY A 266ALA A 162ALA A 165LEU A 413 | None | 0.94A | 3p5nA-5ysmA:2.7 | 3p5nA-5ysmA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a31 | PEPTIDYL-TRNAHYDROLASE (Acinetobacterbaumannii) |
no annotation | 5 | LEU A 32GLY A 25ALA A 93LEU A 91LEU A 64 | None | 0.99A | 3p5nA-6a31A:undetectable | 3p5nA-6a31A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a91 | - (-) |
no annotation | 5 | THR A1059ASP A1356GLY A1354ALA A1353LEU A 374 | None9SL A1610 (-2.8A)9SL A1610 (-3.3A)9SL A1610 ( 3.9A)None | 1.07A | 3p5nA-6a91A:1.6 | 3p5nA-6a91A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eio | ANTIFREEZE PROTEIN (unculturedbacterium) |
no annotation | 5 | GLY A 214ALA A 193ALA A 191LEU A 187LEU A 230 | None | 1.16A | 3p5nA-6eioA:undetectable | 3p5nA-6eioA:19.35 |