SIMILAR PATTERNS OF AMINO ACIDS FOR 3P4W_D_DSFD319
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1edy | ALPHA1-MACROGLOBULIN (Rattusnorvegicus) |
PF07677(A2M_recep) | 5 | ILE A 30VAL A 32TYR A 115ILE A 45ILE A 84 | None | 1.18A | 3p4wD-1edyA:2.5 | 3p4wD-1edyA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g5c | BETA-CARBONICANHYDRASE (Methanothermobacterthermautotrophicus) |
PF00484(Pro_CA) | 5 | ILE A 67ILE A 145VAL A 62ILE A 82ILE A 30 | None | 1.14A | 3p4wD-1g5cA:0.0 | 3p4wD-1g5cA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gns | SUBTILISIN BPN' (Bacillusamyloliquefaciens) |
PF00082(Peptidase_S8) | 5 | MET A 124VAL A 139TYR A 104ILE A 107ILE A 111 | None | 1.14A | 3p4wD-1gnsA:0.0 | 3p4wD-1gnsA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hr7 | MITOCHONDRIALPROCESSING PEPTIDASEBETA SUBUNIT (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | ILE B 352ILE B 356VAL B 349ILE B 270ILE B 268 | None | 1.18A | 3p4wD-1hr7B:0.0 | 3p4wD-1hr7B:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hr7 | MITOCHONDRIALPROCESSING PEPTIDASEBETA SUBUNIT (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | TYR B 455ILE B 456MET B 441VAL B 353ILE B 268 | None | 1.20A | 3p4wD-1hr7B:0.0 | 3p4wD-1hr7B:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kny | KANAMYCINNUCLEOTIDYLTRANSFERASE (Staphylococcusaureus) |
PF07827(KNTase_C) | 5 | TYR A 110ILE A 34ILE A 109MET A 53ILE A 19 | None | 1.19A | 3p4wD-1knyA:2.5 | 3p4wD-1knyA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsl | PROBABLEACETYLTRANSFERASE (Bacillussubtilis) |
PF13302(Acetyltransf_3) | 5 | ILE A 110ILE A 82VAL A 144ILE A 96ILE A 132 | CL A 184 ( 4.2A)NoneNoneNoneNone | 1.05A | 3p4wD-1nslA:0.0 | 3p4wD-1nslA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p3w | CYSTEINE DESULFURASE (Escherichiacoli) |
no annotation | 5 | ILE B 98ILE B 97THR B 145ILE B 146ILE B 175 | None | 1.15A | 3p4wD-1p3wB:0.0 | 3p4wD-1p3wB:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ps9 | 2,4-DIENOYL-COAREDUCTASE (Escherichiacoli) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 5 | ILE A 237ILE A 245VAL A 198ILE A 212ILE A 211 | None | 1.00A | 3p4wD-1ps9A:0.0 | 3p4wD-1ps9A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 5 | PRO A 285ILE A 104ILE A 282THR A 227ILE A 231 | NoneNoneHEA A 602 ( 4.7A)NoneNone | 1.16A | 3p4wD-1qleA:undetectable | 3p4wD-1qleA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu9 | YJGF PROTEIN (Escherichiacoli) |
PF01042(Ribonuc_L-PSP) | 5 | ILE A 71VAL A 61THR A 29ILE A 28ILE A 27 | None | 1.02A | 3p4wD-1qu9A:undetectable | 3p4wD-1qu9A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qxy | METHIONYLAMINOPEPTIDASE (Staphylococcusaureus) |
PF00557(Peptidase_M24) | 5 | ILE A 68VAL A 90THR A 30ILE A 34ILE A 84 | None | 0.79A | 3p4wD-1qxyA:undetectable | 3p4wD-1qxyA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w36 | EXODEOXYRIBONUCLEASEV GAMMA CHAIN (Escherichiacoli) |
PF04257(Exonuc_V_gamma) | 5 | ILE C 729ILE C 374VAL C 748ILE C 755ILE C 752 | None | 1.17A | 3p4wD-1w36C:3.1 | 3p4wD-1w36C:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y7e | PROBABLE M18-FAMILYAMINOPEPTIDASE 1 (Borreliellaburgdorferi) |
PF02127(Peptidase_M18) | 5 | ILE A 221ILE A 215VAL A 141ILE A 137ILE A 231 | None | 1.22A | 3p4wD-1y7eA:undetectable | 3p4wD-1y7eA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z68 | FIBROBLASTACTIVATION PROTEIN,ALPHA SUBUNIT (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | TYR A 67ILE A 62TYR A 87ILE A 89ILE A 76 | None | 0.90A | 3p4wD-1z68A:undetectable | 3p4wD-1z68A:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fea | 2-HYDROXY-3-KETO-5-METHYLTHIOPENTENYL-1-PHOSPHATEPHOSPHATASE (Bacillussubtilis) |
PF12710(HAD) | 5 | ILE A 22MET A 102VAL A 52ILE A 131ILE A 133 | EDO A1306 ( 3.8A)NoneNoneNoneNone | 1.20A | 3p4wD-2feaA:undetectable | 3p4wD-2feaA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gno | DNA POLYMERASE III,GAMMASUBUNIT-RELATEDPROTEIN (Thermotogamaritima) |
PF13177(DNA_pol3_delta2) | 5 | PRO A 46ILE A 94VAL A 121ILE A 30ILE A 28 | None | 1.22A | 3p4wD-2gnoA:undetectable | 3p4wD-2gnoA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gx8 | NIF3-RELATED PROTEIN (Bacillus cereus) |
PF01784(NIF3) | 5 | ILE A 88ILE A 89VAL A 49ILE A 33ILE A 99 | None | 1.14A | 3p4wD-2gx8A:undetectable | 3p4wD-2gx8A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gz3 | ASPARTATEBETA-SEMIALDEHYDEDEHYDROGENASE (Streptococcuspneumoniae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | ILE A 317ILE A 258MET A 319VAL A 269ILE A 273 | None | 1.11A | 3p4wD-2gz3A:undetectable | 3p4wD-2gz3A:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6r | TRIOSEPHOSPHATEISOMERASE (Methanocaldococcusjannaschii) |
PF00121(TIM) | 5 | ILE A 24ILE A 21VAL A 28ILE A 5ILE A 36 | None | 1.10A | 3p4wD-2h6rA:undetectable | 3p4wD-2h6rA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj0 | PUTATIVE CITRATELYASE, ALFA SUBUNIT (Streptococcusmutans) |
PF04223(CitF) | 5 | ILE A 497ILE A 432VAL A 508THR A 387ILE A 393 | None | 0.91A | 3p4wD-2hj0A:undetectable | 3p4wD-2hj0A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hqr | PUTATIVETRANSCRIPTIONALREGULATOR (Helicobacterpylori) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 5 | ILE A 172VAL A 151TYR A 212ILE A 188ILE A 191 | None | 1.16A | 3p4wD-2hqrA:undetectable | 3p4wD-2hqrA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jdf | GAMMA CRYSTALLIN B (Homo sapiens) |
PF00030(Crystall) | 5 | PRO A 148ILE A 81MET A 43VAL A 170ILE A 132 | None | 1.12A | 3p4wD-2jdfA:undetectable | 3p4wD-2jdfA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmo | SER/THR PROTEINKINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | ILE X 12VAL X 113TYR X 28ILE X 116ILE X 115 | None | 1.14A | 3p4wD-2pmoX:undetectable | 3p4wD-2pmoX:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETA (Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | TYR B 327ILE B 324ILE B 323VAL B 139ILE B 184 | None | 1.11A | 3p4wD-2v4jB:undetectable | 3p4wD-2v4jB:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2va1 | URIDYLATE KINASE (Ureaplasmaparvum) |
PF00696(AA_kinase) | 5 | ILE A 38ILE A 220VAL A 44ILE A 10ILE A 46 | None | 1.22A | 3p4wD-2va1A:undetectable | 3p4wD-2va1A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wwd | 1,4-BETA-N-ACETYLMURAMIDASE (Streptococcuspneumoniae) |
PF01183(Glyco_hydro_25)PF01473(CW_binding_1) | 5 | PRO A 323ILE A 288TYR A 358ILE A 271ILE A 272 | None | 1.06A | 3p4wD-2wwdA:undetectable | 3p4wD-2wwdA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x49 | INVASION PROTEININVA (Salmonellaenterica) |
PF00771(FHIPEP) | 5 | ILE A 601ILE A 654MET A 657VAL A 600ILE A 628 | None | 1.15A | 3p4wD-2x49A:undetectable | 3p4wD-2x49A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5q | SSO1986 (Sulfolobussolfataricus) |
no annotation | 5 | TYR A 37ILE A 27ILE A 35VAL A 157ILE A 15 | None | 1.05A | 3p4wD-2x5qA:undetectable | 3p4wD-2x5qA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsb | HYALURONOGLUCOSAMINIDASE (Oceanicolagranulosus) |
PF07555(NAGidase) | 5 | PRO A 255ILE A 266MET A 31THR A 253ILE A 252 | None | 1.17A | 3p4wD-2xsbA:3.6 | 3p4wD-2xsbA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahi | XYLULOSE5-PHOSPHATE/FRUCTOSE6-PHOSPHATEPHOSPHOKETOLASE (Bifidobacteriumbreve) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 5 | ILE A 432ILE A 497TYR A 418ILE A 422ILE A 423 | None | 0.90A | 3p4wD-3ahiA:undetectable | 3p4wD-3ahiA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 5 | ILE A 432TYR A 418THR A 419ILE A 422ILE A 423 | None | 1.21A | 3p4wD-3ai7A:undetectable | 3p4wD-3ai7A:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cjm | PUTATIVEBETA-LACTAMASE (Enterococcusfaecalis) |
PF13354(Beta-lactamase2) | 5 | TYR A 229ILE A 232MET A 236TYR A 220ILE A 270 | None | 1.17A | 3p4wD-3cjmA:undetectable | 3p4wD-3cjmA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3csk | PROBABLEDIPEPTIDYL-PEPTIDASE3 (Saccharomycescerevisiae) |
PF03571(Peptidase_M49) | 5 | PRO A 111TYR A 163ILE A 158ILE A 62ILE A 65 | None | 1.07A | 3p4wD-3cskA:undetectable | 3p4wD-3cskA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3q | TRNADELTA(2)-ISOPENTENYLPYROPHOSPHATETRANSFERASE (Staphylococcusepidermidis) |
PF01715(IPPT) | 5 | ILE A 100ILE A 101TYR A 196ILE A 89ILE A 92 | None | 0.93A | 3p4wD-3d3qA:undetectable | 3p4wD-3d3qA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5l | REGULATORY PROTEINRECX (Lactobacillusreuteri) |
PF02631(RecX) | 5 | TYR A 24ILE A 18VAL A 28ILE A 49ILE A 52 | None | 0.99A | 3p4wD-3d5lA:undetectable | 3p4wD-3d5lA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fys | PROTEIN DEGV (Bacillussubtilis) |
PF02645(DegV) | 5 | ILE A 203ILE A 189MET A 160ILE A 213ILE A 210 | NoneNone BR A 702 (-4.8A)NoneNone | 1.23A | 3p4wD-3fysA:undetectable | 3p4wD-3fysA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gbv | PUTATIVE LACI-FAMILYTRANSCRIPTIONALREGULATOR (Bacteroidesfragilis) |
PF13407(Peripla_BP_4) | 5 | ILE A 157ILE A 155VAL A 84ILE A 319ILE A 88 | None | 1.17A | 3p4wD-3gbvA:undetectable | 3p4wD-3gbvA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1t | TYPE I SITE-SPECIFICRESTRICTION-MODIFICATION SYSTEM, R(RESTRICTION)SUBUNIT (Vibriovulnificus) |
PF00271(Helicase_C)PF04851(ResIII)PF13588(HSDR_N_2) | 5 | TYR A 358ILE A 203ILE A 357VAL A 214ILE A 218 | None | 1.11A | 3p4wD-3h1tA:undetectable | 3p4wD-3h1tA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6r | DIHYDROOROTATEDEHYDROGENASEHOMOLOG,MITOCHONDRIAL (Plasmodiumfalciparum) |
PF01180(DHO_dh) | 5 | PRO A 424ILE A 329VAL A 367TYR A 338ILE A 341 | None | 0.99A | 3p4wD-3i6rA:undetectable | 3p4wD-3i6rA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3irv | CYSTEINE HYDROLASE (Pseudomonassavastanoi) |
PF00857(Isochorismatase) | 5 | ILE A 53ILE A 169VAL A 55THR A 183ILE A 184 | None | 1.12A | 3p4wD-3irvA:undetectable | 3p4wD-3irvA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2n | SIGMA-54-DEPENDENTTRANSCRIPTIONALREGULATOR (Chlorobaculumtepidum) |
PF13185(GAF_2) | 5 | ILE A 40ILE A 41VAL A 161ILE A 43ILE A 129 | None | 0.94A | 3p4wD-3k2nA:3.1 | 3p4wD-3k2nA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ktw | SIGNAL RECOGNITIONPARTICLE 19 KDAPROTEIN (Sulfolobussolfataricus) |
PF01922(SRP19) | 5 | VAL A 73TYR A 81THR A 82ILE A 85ILE A 86 | None | 0.85A | 3p4wD-3ktwA:undetectable | 3p4wD-3ktwA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnl | UPF0135 PROTEINSA1388 (Staphylococcusaureus) |
PF01784(NIF3) | 5 | ILE A 326ILE A 328VAL A 304ILE A 285ILE A 283 | None | 1.21A | 3p4wD-3lnlA:undetectable | 3p4wD-3lnlA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwu | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Shewanellafrigidimarina) |
PF04952(AstE_AspA) | 5 | TYR A 265ILE A 262VAL A 271ILE A 39ILE A 70 | None | 1.04A | 3p4wD-3lwuA:undetectable | 3p4wD-3lwuA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpg | DIHYDROOROTASE (Bacillusanthracis) |
PF01979(Amidohydro_1) | 5 | ILE A 378ILE A 376MET A 412VAL A 46ILE A 44 | None | 1.22A | 3p4wD-3mpgA:undetectable | 3p4wD-3mpgA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ppo | GLYCINEBETAINE/CARNITINE/CHOLINE-BINDINGPROTEIN (Bacillussubtilis) |
PF04069(OpuAC) | 5 | ILE A 262ILE A 247VAL A 261ILE A 34ILE A 55 | None | 1.18A | 3p4wD-3ppoA:undetectable | 3p4wD-3ppoA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgw | MEMBRANE-BOUNDHYDROGENASE (NIFE)LARGE SUBUNIT HOXG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 5 | ILE L 222ILE L 219VAL L 253ILE L 108ILE L 105 | None | 1.12A | 3p4wD-3rgwL:1.2 | 3p4wD-3rgwL:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rys | ADENOSINE DEAMINASE1 (Paenarthrobacteraurescens) |
PF00962(A_deaminase) | 5 | PRO A 104ILE A 165VAL A 121ILE A 139ILE A 100 | None | 1.15A | 3p4wD-3rysA:undetectable | 3p4wD-3rysA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3srt | MALTOSEO-ACETYLTRANSFERASE (Clostridioidesdifficile) |
PF12464(Mac)PF14602(Hexapep_2) | 5 | ILE A 156ILE A 166VAL A 142ILE A 148ILE A 144 | None | 1.04A | 3p4wD-3srtA:undetectable | 3p4wD-3srtA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3su8 | PLEXIN-B1 (Homo sapiens) |
PF08337(Plexin_cytopl) | 5 | PRO X1706ILE X1940VAL X1699ILE X1990ILE X1989 | None | 1.17A | 3p4wD-3su8X:undetectable | 3p4wD-3su8X:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t63 | PROTOCATECHUATE3,4-DIOXYGENASE BETACHAIN (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF12391(PCDO_beta_N) | 5 | ILE M 461VAL M 380THR M 441ILE M 442ILE M 378 | None | 1.18A | 3p4wD-3t63M:undetectable | 3p4wD-3t63M:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tow | MULTIVESICULAR BODYSUBUNIT 12B (Homo sapiens) |
PF10240(DUF2464) | 5 | ILE A 148MET A 114VAL A 53ILE A 160ILE A 163 | None | 1.23A | 3p4wD-3towA:undetectable | 3p4wD-3towA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7w | URIDYLATE KINASE (Helicobacterpylori) |
PF00696(AA_kinase) | 5 | ILE A 53ILE A 132MET A 90ILE A 39ILE A 35 | None | 1.19A | 3p4wD-4a7wA:undetectable | 3p4wD-4a7wA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | ILE A 57VAL A 65THR A 153ILE A 145ILE A 157 | None | 1.19A | 3p4wD-4c90A:4.5 | 3p4wD-4c90A:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eqm | PROTEIN KINASE (Staphylococcusaureus) |
PF00069(Pkinase) | 5 | ILE A 195ILE A 121VAL A 198ILE A 149ILE A 139 | None | 1.17A | 3p4wD-4eqmA:undetectable | 3p4wD-4eqmA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3q | TRANSCRIPTIONALREGULATORY PROTEINCBU_1566 (Coxiellaburnetii) |
PF01709(Transcrip_reg) | 5 | ILE A 183ILE A 140VAL A 158ILE A 151ILE A 154 | None | 1.16A | 3p4wD-4f3qA:undetectable | 3p4wD-4f3qA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PRO A 145ILE A 105ILE A 128ILE A 142ILE A 119 | None | 1.16A | 3p4wD-4fs7A:undetectable | 3p4wD-4fs7A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gd3 | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
no annotation | 5 | PRO S 170TYR S 162ILE S 159ILE S 110ILE S 72 | None | 1.21A | 3p4wD-4gd3S:undetectable | 3p4wD-4gd3S:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl6 | HYPOTHETICAL PROTEIN ([Ruminococcus]gnavus) |
PF16440(DUF5037) | 5 | TYR A 203ILE A 169TYR A 186ILE A 115ILE A 124 | NoneNoneNoneNoneGOL A 301 ( 4.0A) | 1.19A | 3p4wD-4gl6A:undetectable | 3p4wD-4gl6A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gv8 | DUTPASE (Staphylococcusvirus 11) |
PF00692(dUTPase) | 5 | TYR A 126ILE A 110ILE A 128VAL A 67ILE A 90 | None | 1.07A | 3p4wD-4gv8A:undetectable | 3p4wD-4gv8A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iql | ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASEII (Porphyromonasgingivalis) |
PF03060(NMO) | 5 | PRO A 70VAL A 91TYR A 73ILE A 79ILE A 83 | FMN A 401 ( 4.5A)NoneNDP A 403 (-4.4A)NoneNone | 1.23A | 3p4wD-4iqlA:undetectable | 3p4wD-4iqlA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0m | SERINE/THREONINE-PROTEIN KINASEBRI1-LIKE 1 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | PRO A 564ILE A 646VAL A 651ILE A 655ILE A 675 | None | 1.03A | 3p4wD-4j0mA:undetectable | 3p4wD-4j0mA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k59 | RNA BINDING PROTEINRSMF (Pseudomonasaeruginosa) |
PF02599(CsrA) | 5 | ILE A 39ILE A 41VAL A 61ILE A 17ILE A 63 | None | 1.22A | 3p4wD-4k59A:undetectable | 3p4wD-4k59A:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqn | D-HYDANTOINASE (Bacillus sp.AR9) |
PF01979(Amidohydro_1) | 5 | ILE A 5ILE A 395VAL A 21ILE A 51ILE A 385 | ILE A 5 ( 0.6A)ILE A 395 ( 0.4A)VAL A 21 ( 0.5A)ILE A 51 ( 0.7A)ILE A 385 ( 0.7A) | 1.13A | 3p4wD-4kqnA:undetectable | 3p4wD-4kqnA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lfn | GALACTOSE-6-PHOSPHATE ISOMERASE SUBUNITB (Lactobacillusrhamnosus) |
PF02502(LacAB_rpiB) | 5 | ILE B 62ILE B 5MET B 64VAL B 120ILE B 116 | None | 1.06A | 3p4wD-4lfnB:undetectable | 3p4wD-4lfnB:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ILE A 347ILE A 349VAL A 337ILE A 367ILE A 375 | None | 1.05A | 3p4wD-4lvcA:undetectable | 3p4wD-4lvcA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ILE A 375ILE A 367MET A 377ILE A 349ILE A 347 | None | 0.90A | 3p4wD-4lvcA:undetectable | 3p4wD-4lvcA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 5 | PRO A 102VAL A 27TYR A 99ILE A 76ILE A 6 | None | 1.18A | 3p4wD-4mptA:undetectable | 3p4wD-4mptA:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovr | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Xanthobacterautotrophicus) |
PF03480(DctP) | 5 | ILE A 317ILE A 320MET A 316VAL A 308ILE A 128 | None | 1.16A | 3p4wD-4ovrA:undetectable | 3p4wD-4ovrA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pay | SIDC, INTERAPTIN (Legionellapneumophila) |
no annotation | 5 | TYR A 19ILE A 30TYR A 76ILE A 112ILE A 116 | None | 1.11A | 3p4wD-4payA:undetectable | 3p4wD-4payA:19.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 8 | PRO A 120ILE A 208ILE A 209MET A 212TYR A 261THR A 262ILE A 265ILE A 266 | None | 0.74A | 3p4wD-4yeuA:19.9 | 3p4wD-4yeuA:52.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 7 | TYR A 204ILE A 208ILE A 209MET A 212THR A 262ILE A 265ILE A 266 | None | 0.76A | 3p4wD-4yeuA:19.9 | 3p4wD-4yeuA:52.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 5 | TYR A 204ILE A 208ILE A 209MET A 212VAL A 249 | None | 1.14A | 3p4wD-4yeuA:19.9 | 3p4wD-4yeuA:52.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | PRO A 164ILE A 181ILE A 174VAL A 263ILE A 159 | None | 1.17A | 3p4wD-4zqgA:undetectable | 3p4wD-4zqgA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zuz | SIDC (Legionellapneumophila) |
no annotation | 5 | TYR A 20ILE A 31TYR A 77ILE A 113ILE A 117 | None | 1.17A | 3p4wD-4zuzA:4.8 | 3p4wD-4zuzA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0z | CHOLINETRIMETHYLAMINE LYASE (Klebsiellapneumoniae) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | ILE A 795ILE A 793VAL A 831ILE A 838ILE A 835 | None | 1.20A | 3p4wD-5a0zA:2.7 | 3p4wD-5a0zA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4m | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 5 | PRO S 170TYR S 162ILE S 159ILE S 110ILE S 72 | None | 1.05A | 3p4wD-5a4mS:undetectable | 3p4wD-5a4mS:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejb | FUSION GLYCOPROTEINF0 (Hendrahenipavirus) |
no annotation | 5 | TYR B 275ILE B 277ILE B 276ILE B 90ILE B 94 | None | 1.10A | 3p4wD-5ejbB:undetectable | 3p4wD-5ejbB:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g37 | 41.9 KDAINSECTICIDAL TOXIN (Lysinibacillussphaericus) |
PF05431(Toxin_10) | 5 | ILE A 256ILE A 193VAL A 258THR A 272ILE A 275 | None | 1.14A | 3p4wD-5g37A:undetectable | 3p4wD-5g37A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gai | TAIL FIBER PROTEIN (Salmonellavirus P22) |
no annotation | 5 | ILE Y 82ILE Y 73VAL Y 49ILE Y 31ILE Y 33 | None | 1.08A | 3p4wD-5gaiY:undetectable | 3p4wD-5gaiY:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 5 | ILE A 538ILE A 465VAL A 611ILE A 642ILE A 571 | None | 1.17A | 3p4wD-5j72A:undetectable | 3p4wD-5j72A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j8q | CYSTEINE DESULFURASESUFS (Bacillussubtilis) |
PF00266(Aminotran_5) | 5 | ILE A 3ILE A 6MET A 1TYR A 380ILE A 299 | None | 0.99A | 3p4wD-5j8qA:undetectable | 3p4wD-5j8qA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT ALPHA (Methylobacillusflagellatus) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ILE A 354ILE A 377VAL A 411THR A 416ILE A 338 | None | 1.23A | 3p4wD-5ks8A:undetectable | 3p4wD-5ks8A:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me4 | PROBABLE PHOSPHITETRANSPORTSYSTEM-BINDINGPROTEIN HTXB (Pseudomonasstutzeri) |
no annotation | 5 | ILE A 208VAL A 66TYR A 35ILE A 225ILE A 222 | None | 1.15A | 3p4wD-5me4A:undetectable | 3p4wD-5me4A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n41 | POLB1 BINDINGPROTEIN 2 (Sulfolobussolfataricus) |
no annotation | 5 | ILE A 59MET A 56VAL A 49ILE A 20ILE A 16 | None | 1.23A | 3p4wD-5n41A:undetectable | 3p4wD-5n41A:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5obu | CHAPERONE PROTEINDNAK (Mycoplasmagenitalium) |
no annotation | 5 | ILE A 300ILE A 304VAL A 333ILE A 314ILE A 317 | None | 1.17A | 3p4wD-5obuA:undetectable | 3p4wD-5obuA:13.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olk | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE,BETA SUBUNIT 1 (Leeuwenhoekiellablandensis) |
no annotation | 5 | ILE A 106TYR A 251THR A 252ILE A 255ILE A 309 | None | 1.16A | 3p4wD-5olkA:undetectable | 3p4wD-5olkA:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqr | CONDENSIN COMPLEXSUBUNIT 3 (Schizosaccharomycespombe) |
no annotation | 5 | ILE A 44ILE A 43VAL A 57ILE A 4ILE A 7 | None | 1.10A | 3p4wD-5oqrA:undetectable | 3p4wD-5oqrA:18.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5v6n | PROTON-GATED IONCHANNEL (Gloeobacterviolaceus) |
no annotation | 10 | PRO C 120TYR C 197ILE C 201ILE C 202MET C 205VAL C 242TYR C 254THR C 255ILE C 258ILE C 259 | None | 0.34A | 3p4wD-5v6nC:36.1 | 3p4wD-5v6nC:98.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vft | 26S PROTEASOMEREGULATORY SUBUNIT 8 (Homo sapiens) |
no annotation | 5 | ILE C 292ILE C 245VAL C 186ILE C 165ILE C 161 | None | 1.15A | 3p4wD-5vftC:2.6 | 3p4wD-5vftC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5j | RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2 (Homo sapiens) |
no annotation | 5 | ILE A 162ILE A 152VAL A 132TYR A 192ILE A 218 | None | 1.18A | 3p4wD-5w5jA:undetectable | 3p4wD-5w5jA:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wc8 | SIAD (Mannheimiahaemolytica) |
no annotation | 5 | ILE M 254VAL M 334THR M 345ILE M 348ILE M 352 | None | 1.16A | 3p4wD-5wc8M:undetectable | 3p4wD-5wc8M:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 5 | TYR A 533ILE A 529THR A 609ILE A 612ILE A 613 | None | 1.17A | 3p4wD-5welA:4.0 | 3p4wD-5welA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlh | LBACAS13A H328A(C2C2) (LachnospiraceaebacteriumNK4A179) |
no annotation | 5 | TYR A1334ILE A1376VAL A1294ILE A1361ILE A1360 | None | 1.15A | 3p4wD-5wlhA:1.9 | 3p4wD-5wlhA:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ILE A 311VAL A 287THR A 279ILE A 278ILE A 277 | None | 1.17A | 3p4wD-6aphA:undetectable | 3p4wD-6aphA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cza | () |
no annotation | 5 | ILE A 269TYR B 234THR A 353ILE A 357ILE A 354 | None | 1.07A | 3p4wD-6czaA:undetectable | 3p4wD-6czaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dus | TYPE III SECRETIONSYSTEM EFFECTORPROTEIN (Salmonellaenterica) |
no annotation | 5 | ILE A 65VAL A 93TYR A 114ILE A 80ILE A 79 | NoneNoneNoneMPD A 506 (-4.5A)None | 0.98A | 3p4wD-6dusA:undetectable | 3p4wD-6dusA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fea | NITROGENASE PROTEINALPHA CHAIN (Azotobactervinelandii) |
no annotation | 5 | ILE A 279VAL A 254TYR A 223ILE A 291ILE A 294 | None | 1.22A | 3p4wD-6feaA:undetectable | 3p4wD-6feaA:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fyl | DUAL SPECIFICITYPROTEIN KINASE CLK2 (Homo sapiens) |
no annotation | 5 | ILE A 296VAL A 278TYR A 347ILE A 370ILE A 367 | None | 1.20A | 3p4wD-6fylA:undetectable | 3p4wD-6fylA:undetectable |