SIMILAR PATTERNS OF AMINO ACIDS FOR 3P4W_C_DSFC320_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1coz | PROTEIN(GLYCEROL-3-PHOSPHATECYTIDYLYLTRANSFERASE) (Bacillussubtilis) |
PF01467(CTP_transf_like) | 4 | TYR A 52ILE A 35VAL A 68ILE A 58 | None | 0.83A | 3p4wC-1cozA:undetectable | 3p4wC-1cozA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dy6 | CARBAPENEM-HYDROLYSING BETA-LACTAMASESME-1 (Serratiamarcescens) |
PF13354(Beta-lactamase2) | 4 | ILE A 263ILE A 221VAL A 46ILE A 287 | None | 0.88A | 3p4wC-1dy6A:0.0 | 3p4wC-1dy6A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecg | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Escherichiacoli) |
PF00156(Pribosyltran)PF13522(GATase_6) | 4 | PRO A 251ILE A 269ILE A 266VAL A 446 | None | 0.78A | 3p4wC-1ecgA:0.0 | 3p4wC-1ecgA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fpr | PROTEIN-TYROSINEPHOSPHATASE 1C (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | TYR A 511TYR A 507ILE A 490ILE A 468 | None | 0.74A | 3p4wC-1fprA:undetectable | 3p4wC-1fprA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2u | 20 KDA NUCLEAR CAPBINDING PROTEIN (Homo sapiens) |
PF00076(RRM_1) | 4 | TYR X 57ILE X 56VAL X 86ILE X 101 | None | 0.88A | 3p4wC-1h2uX:undetectable | 3p4wC-1h2uX:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4m | NAMNADENYLYLTRANSFERASE (Escherichiacoli) |
PF01467(CTP_transf_like) | 4 | TYR A 120PRO A 115TYR A 146ILE A 169 | None | 0.75A | 3p4wC-1k4mA:undetectable | 3p4wC-1k4mA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ldk | CULLIN HOMOLOG (Homo sapiens) |
PF00888(Cullin)PF10557(Cullin_Nedd8) | 4 | TYR B 455ILE A 403ILE B 456VAL A 370 | None | 0.84A | 3p4wC-1ldkB:0.4 | 3p4wC-1ldkB:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 122ILE A 125ILE A 126ILE A 74 | None | 0.67A | 3p4wC-1pm2A:2.2 | 3p4wC-1pm2A:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdl | PROTEIN(ANTHRANILATESYNTHASE(TRPG-SUBUNIT)) (Sulfolobussolfataricus) |
PF00117(GATase) | 4 | ILE B 7ILE B 31VAL B 70ILE B 44 | None | 0.80A | 3p4wC-1qdlB:undetectable | 3p4wC-1qdlB:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgm | 378AA LONGHYPOTHETICAL CITRATESYNTHASE (Sulfurisphaeratokodaii) |
PF00285(Citrate_synt) | 4 | ILE A 207VAL A 340THR A 128ILE A 131 | None | 0.81A | 3p4wC-1vgmA:undetectable | 3p4wC-1vgmA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf2 | TYPE IRESTRICTION-MODIFICATION ENZYME, SSUBUNIT (Methanocaldococcusjannaschii) |
PF01420(Methylase_S) | 4 | ILE A 236ILE A 233VAL A 335ILE A 300 | None | 0.85A | 3p4wC-1yf2A:1.7 | 3p4wC-1yf2A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | ILE A 583ILE A 584VAL A 642ILE A 629 | None | 0.65A | 3p4wC-1ygpA:undetectable | 3p4wC-1ygpA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z2f | ANTIFREEZE PROTEINISOFORM 501 (Choristoneurafumiferana) |
PF05264(CfAFP) | 4 | TYR A 64TYR A 77ILE A 76ILE A 58 | None | 0.79A | 3p4wC-1z2fA:undetectable | 3p4wC-1z2fA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3v | CELLULASE (Phanerochaetechrysosporium) |
PF00840(Glyco_hydro_7) | 4 | PRO A 12TYR A 78ILE A 84VAL A 105 | None | 0.77A | 3p4wC-1z3vA:undetectable | 3p4wC-1z3vA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zgj | ISOFLAVANONE4'-O-METHYLTRANSFERASE' (Medicagotruncatula) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 4 | ILE A 296ILE A 298VAL A 196ILE A 353 | None | 0.80A | 3p4wC-1zgjA:undetectable | 3p4wC-1zgjA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zgx | GUANYL-SPECIFICRIBONUCLEASE SA (Kitasatosporaaureofaciens) |
PF00545(Ribonuclease) | 4 | TYR B 80ILE B 71ILE B 70ILE A 22 | None | 0.85A | 3p4wC-1zgxB:undetectable | 3p4wC-1zgxB:8.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghi | TRANSPORT PROTEIN (Plasmodiumyoelii) |
PF00005(ABC_tran) | 4 | ILE A 91ILE A 95VAL A 83ILE A 18 | None | 0.81A | 3p4wC-2ghiA:undetectable | 3p4wC-2ghiA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpg | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Thermotogamaritima) |
PF03480(DctP) | 4 | TYR A 260ILE A 263ILE A 264ILE A 59 | None | 0.67A | 3p4wC-2hpgA:undetectable | 3p4wC-2hpgA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k53 | A3DK08 PROTEIN (Ruminiclostridiumthermocellum) |
PF08984(DUF1858) | 4 | ILE A 3VAL A 12THR A 19ILE A 22 | None | 0.86A | 3p4wC-2k53A:undetectable | 3p4wC-2k53A:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kxp | F-ACTIN-CAPPINGPROTEIN SUBUNIT BETAISOFORMS 1 AND 2 (Gallus gallus) |
PF01115(F_actin_cap_B) | 4 | TYR B 407ILE B 432VAL B 517ILE B 510 | None | 0.87A | 3p4wC-2kxpB:undetectable | 3p4wC-2kxpB:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l2b | STICHOLYSIN-2 (Stichodactylahelianthus) |
PF06369(Anemone_cytotox) | 5 | TYR A 90ILE A 171ILE A 173VAL A 100ILE A 119 | None | 1.08A | 3p4wC-2l2bA:undetectable | 3p4wC-2l2bA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pz0 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Caldanaerobactersubterraneus) |
PF03009(GDPD) | 4 | ILE A 135ILE A 138VAL A 160ILE A 118 | None | 0.80A | 3p4wC-2pz0A:undetectable | 3p4wC-2pz0A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzx | HEPATOCYTE GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF01403(Sema)PF01437(PSI)PF01833(TIG) | 4 | TYR B 321ILE B 446VAL B 492ILE B 452 | None | 0.83A | 3p4wC-2uzxB:undetectable | 3p4wC-2uzxB:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v1u | CELL DIVISIONCONTROL PROTEIN 6HOMOLOG (Aeropyrumpernix) |
PF09079(Cdc6_C)PF13191(AAA_16) | 4 | TYR A 330ILE A 350ILE A 351ILE A 311 | None | 0.66A | 3p4wC-2v1uA:undetectable | 3p4wC-2v1uA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v3c | SIGNAL RECOGNITION54 KDA PROTEIN (Methanocaldococcusjannaschii) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 4 | ILE C 215ILE C 216VAL C 238ILE C 244 | None | 0.88A | 3p4wC-2v3cC:2.8 | 3p4wC-2v3cC:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk9 | ALPHA-TOXIN (Clostridiumnovyi) |
PF12918(TcdB_N)PF12919(TcdA_TcdB) | 4 | ILE A 340ILE A 299VAL A 336ILE A 314 | None | 0.87A | 3p4wC-2vk9A:3.7 | 3p4wC-2vk9A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xtl | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF16569(GramPos_pilinBB)PF16570(GramPos_pilinD3) | 4 | PRO A 195TYR A 331THR A 232ILE A 305 | None | 0.85A | 3p4wC-2xtlA:2.4 | 3p4wC-2xtlA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xym | RNA-DIRECTED RNAPOLYMERASE (Hepacivirus C) |
PF00998(RdRP_3) | 4 | ILE A 462ILE A 463VAL A 454ILE A 412 | None | 0.87A | 3p4wC-2xymA:undetectable | 3p4wC-2xymA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqe | JUMONJI/ARIDDOMAIN-CONTAININGPROTEIN 1D (Homo sapiens) |
PF01388(ARID) | 4 | TYR A 164ILE A 161ILE A 160ILE A 102 | None | 0.87A | 3p4wC-2yqeA:undetectable | 3p4wC-2yqeA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwt | PROTEIN PUF4 (Saccharomycescerevisiae) |
PF00806(PUF) | 4 | TYR A 775VAL A 811THR A 778ILE A 781 | None | 0.81A | 3p4wC-3bwtA:undetectable | 3p4wC-3bwtA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clh | 3-DEHYDROQUINATESYNTHASE (Helicobacterpylori) |
PF01761(DHQ_synthase) | 4 | ILE A 32ILE A 31VAL A 101ILE A 117 | None | 0.83A | 3p4wC-3clhA:undetectable | 3p4wC-3clhA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cob | KINESIN HEAVYCHAIN-LIKE PROTEIN (Solanumtuberosum) |
PF00225(Kinesin) | 4 | TYR A 981ILE A 966VAL A1093THR A 990 | None | 0.82A | 3p4wC-3cobA:undetectable | 3p4wC-3cobA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9y | ACETOLACTATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ILE A 234ILE A 235VAL A 225ILE A 192 | None | 0.85A | 3p4wC-3e9yA:undetectable | 3p4wC-3e9yA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6t | ASPARTATEAMINOTRANSFERASE (Lactobacillusacidophilus) |
PF00155(Aminotran_1_2) | 4 | TYR A 510ILE A 513VAL A 489ILE A 446 | None | 0.79A | 3p4wC-3f6tA:undetectable | 3p4wC-3f6tA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq9 | PRENECK APPENDAGEPROTEIN (Bacillus virusphi29) |
PF11962(Peptidase_G2)PF12708(Pectate_lyase_3) | 4 | ILE A 269VAL A 318THR A 284ILE A 244 | None | 0.75A | 3p4wC-3gq9A:undetectable | 3p4wC-3gq9A:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h9m | P-AMINOBENZOATESYNTHETASE,COMPONENT I (Cytophagahutchinsonii) |
PF00425(Chorismate_bind) | 4 | TYR A 186ILE A 401ILE A 184ILE A 175 | None | 0.87A | 3p4wC-3h9mA:undetectable | 3p4wC-3h9mA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i7f | ASPARTYL-TRNASYNTHETASE (Entamoebahistolytica) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | ILE A 468ILE A 514VAL A 463ILE A 357 | None | 0.86A | 3p4wC-3i7fA:undetectable | 3p4wC-3i7fA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igx | TRANSALDOLASE (Francisellatularensis) |
PF00923(TAL_FSA) | 4 | ILE A 134ILE A 154VAL A 100ILE A 112 | None | 0.85A | 3p4wC-3igxA:undetectable | 3p4wC-3igxA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihy | PHOSPHATIDYLINOSITOL3-KINASE CATALYTICSUBUNIT TYPE 3 (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka) | 4 | ILE A 738ILE A 735VAL A 842ILE A 647 | None | 0.84A | 3p4wC-3ihyA:undetectable | 3p4wC-3ihyA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipj | PTS SYSTEM, IIABCCOMPONENT (Clostridioidesdifficile) |
PF00367(PTS_EIIB) | 4 | ILE A 14ILE A 17VAL A 79ILE A 65 | None | 0.80A | 3p4wC-3ipjA:undetectable | 3p4wC-3ipjA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j26 | CAPSID PROTEIN V20 (Mimivirus-dependentvirus Sputnik) |
no annotation | 4 | ILE A 103ILE A 106VAL A 71ILE A 262 | None | 0.78A | 3p4wC-3j26A:undetectable | 3p4wC-3j26A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l4k | DNA TOPOISOMERASE 2 (Saccharomycescerevisiae) |
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C) | 4 | ILE A 495ILE A 498VAL A 481ILE A 538 | None | 0.72A | 3p4wC-3l4kA:undetectable | 3p4wC-3l4kA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lah | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Caldanaerobactersubterraneus) |
PF07700(HNOB) | 4 | TYR A 17ILE A 51VAL A 70ILE A 10 | None | 0.78A | 3p4wC-3lahA:undetectable | 3p4wC-3lahA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mda | DNA POLYMERASELAMBDA (Homo sapiens) |
PF10391(DNA_pol_lambd_f)PF14716(HHH_8)PF14791(DNA_pol_B_thumb)PF14792(DNA_pol_B_palm) | 4 | TYR A 496PRO A 435THR A 433ILE A 432 | None | 0.72A | 3p4wC-3mdaA:undetectable | 3p4wC-3mdaA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgw | LYSOZYME G (Salmo salar) |
PF01464(SLT) | 4 | ILE A 127ILE A 124VAL A 154ILE A 144 | None | 0.88A | 3p4wC-3mgwA:undetectable | 3p4wC-3mgwA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 4 | PRO A1024ILE A 991ILE A 992VAL A 936 | None | 0.83A | 3p4wC-3ne5A:2.4 | 3p4wC-3ne5A:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | ILE A 329VAL A 291THR A 395ILE A 369 | None | 0.87A | 3p4wC-3ojlA:undetectable | 3p4wC-3ojlA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3orj | SUGAR-BINDINGPROTEIN (Bacteroidesovatus) |
no annotation | 4 | PRO A 354ILE A 320ILE A 441VAL A 372 | None | 0.75A | 3p4wC-3orjA:undetectable | 3p4wC-3orjA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovg | AMIDOHYDROLASE (Mycoplasmasynoviae) |
PF02126(PTE) | 4 | ILE A 64VAL A 9THR A 79ILE A 82 | None | 0.84A | 3p4wC-3ovgA:undetectable | 3p4wC-3ovgA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q87 | N6 ADENINE SPECIFICDNA METHYLASE (Encephalitozooncuniculi) |
PF05175(MTS) | 4 | PRO B 129TYR B 157ILE B 145ILE B 159 | None | 0.85A | 3p4wC-3q87B:undetectable | 3p4wC-3q87B:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q94 | FRUCTOSE-BISPHOSPHATE ALDOLASE, CLASS II (Bacillusanthracis) |
PF01116(F_bP_aldolase) | 4 | ILE A 82VAL A 67THR A 31ILE A 34 | None | 0.83A | 3p4wC-3q94A:undetectable | 3p4wC-3q94A:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qth | UNCHARACTERIZEDPROTEIN (Colwelliapsychrerythraea) |
PF09351(DUF1993) | 4 | PRO A 104TYR A 8ILE A 9ILE A 5 | None | 0.87A | 3p4wC-3qthA:2.3 | 3p4wC-3qthA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qyb | TBC1 DOMAIN FAMILYMEMBER 4 (Homo sapiens) |
PF00566(RabGAP-TBC) | 4 | ILE A1108ILE A1109VAL A1164ILE A1117 | None | 0.65A | 3p4wC-3qybA:undetectable | 3p4wC-3qybA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4v | PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasphage 201phi2-1) |
PF00091(Tubulin) | 4 | TYR A 161ILE A 164VAL A 118THR A 13 | GDP A 400 (-3.7A)GDP A 400 (-3.7A)GDP A 400 (-4.6A)GDP A 400 (-3.5A) | 0.82A | 3p4wC-3r4vA:undetectable | 3p4wC-3r4vA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3suc | PRENECK APPENDAGEPROTEIN (Bacillus virusphi29) |
PF11962(Peptidase_G2)PF12708(Pectate_lyase_3) | 4 | ILE A 269VAL A 318THR A 284ILE A 244 | None | 0.75A | 3p4wC-3sucA:undetectable | 3p4wC-3sucA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tb6 | ARABINOSE METABOLISMTRANSCRIPTIONALREPRESSOR (Bacillussubtilis) |
PF13377(Peripla_BP_3) | 4 | ILE A 82ILE A 136VAL A 331ILE A 164 | None | 0.83A | 3p4wC-3tb6A:undetectable | 3p4wC-3tb6A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uhj | PROBABLE GLYCEROLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00465(Fe-ADH) | 4 | TYR A 159ILE A 359ILE A 360ILE A 280 | None | 0.82A | 3p4wC-3uhjA:undetectable | 3p4wC-3uhjA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbj | GALACTOSIDEO-ACETYLTRANSFERASE (Bacillus cereus) |
PF00132(Hexapep) | 4 | TYR A 90ILE A 131ILE A 132ILE A 83 | None | 0.88A | 3p4wC-3vbjA:undetectable | 3p4wC-3vbjA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vhl | DEDICATOR OFCYTOKINESIS PROTEIN8 (Mus musculus) |
PF06920(DHR-2) | 4 | TYR A1863ILE A1846ILE A1864VAL A1852 | None | 0.85A | 3p4wC-3vhlA:2.9 | 3p4wC-3vhlA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vp7 | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 30 (Saccharomycescerevisiae) |
PF04111(APG6) | 4 | ILE A 447ILE A 446VAL A 526ILE A 364 | None | 0.58A | 3p4wC-3vp7A:undetectable | 3p4wC-3vp7A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wyh | LYSOZYME G (Struthiocamelus) |
PF01464(SLT) | 4 | ILE A 127ILE A 124VAL A 154ILE A 144 | None | 0.88A | 3p4wC-3wyhA:undetectable | 3p4wC-3wyhA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdr | ALCOHOLDEHYDROGENASE DOMAINOF THE BIFUNCTIONALACETALDEHYDEDEHYDROGENASE (Parageobacillusthermoglucosidasius) |
PF00465(Fe-ADH) | 4 | ILE A 807ILE A 806VAL A 869ILE A 756 | None | 0.86A | 3p4wC-3zdrA:undetectable | 3p4wC-3zdrA:25.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a22 | FRUCTOSE-BISPHOSPHATE ALDOLASE (Mycobacteriumtuberculosis) |
PF01116(F_bP_aldolase) | 4 | ILE A 26ILE A 50VAL A 328ILE A 38 | None | 0.87A | 3p4wC-4a22A:undetectable | 3p4wC-4a22A:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7l | MYOSIN IE HEAVYCHAIN (Dictyosteliumdiscoideum) |
PF00063(Myosin_head) | 4 | TYR C 630ILE C 670THR C 656ILE C 659 | None | 0.80A | 3p4wC-4a7lC:1.1 | 3p4wC-4a7lC:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4an7 | TRYPSIN INHIBITOR (Tamarindusindica) |
PF00197(Kunitz_legume) | 4 | TYR B 19ILE B 70ILE B 122ILE B 78 | None | 0.84A | 3p4wC-4an7B:undetectable | 3p4wC-4an7B:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7e | UREASE (Cajanus cajan) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 4 | ILE B 364ILE B 359VAL B 697ILE B 721 | None | 0.86A | 3p4wC-4g7eB:undetectable | 3p4wC-4g7eB:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfh | DNA TOPOISOMERASE 2 (Saccharomycescerevisiae) |
PF00204(DNA_gyraseB)PF00521(DNA_topoisoIV)PF01751(Toprim)PF02518(HATPase_c)PF16898(TOPRIM_C) | 4 | ILE A 495ILE A 498VAL A 481ILE A 538 | None | 0.69A | 3p4wC-4gfhA:undetectable | 3p4wC-4gfhA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kp2 | HOMOACONITASE LARGESUBUNIT (Methanocaldococcusjannaschii) |
PF00330(Aconitase) | 4 | ILE A 294ILE A 415VAL A 297ILE A 405 | None | 0.84A | 3p4wC-4kp2A:undetectable | 3p4wC-4kp2A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lix | ENT-COPALYLDIPHOSPHATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | TYR A 357TYR A 361ILE A 367ILE A 332 | None | 0.66A | 3p4wC-4lixA:3.1 | 3p4wC-4lixA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m00 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
PF05345(He_PIG) | 4 | TYR A 446ILE A 332VAL A 316ILE A 433 | None | 0.77A | 3p4wC-4m00A:undetectable | 3p4wC-4m00A:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8j | L-CARNITINE/GAMMA-BUTYROBETAINEANTIPORTER (Proteusmirabilis) |
PF02028(BCCT) | 4 | ILE A 235ILE A 236THR A 419ILE A 423 | None | 0.66A | 3p4wC-4m8jA:2.4 | 3p4wC-4m8jA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | TYR A 258ILE A 261ILE A 262ILE A 66 | None | 0.67A | 3p4wC-4n6kA:undetectable | 3p4wC-4n6kA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4to8 | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE,CLASS II (Staphylococcusaureus) |
PF01116(F_bP_aldolase) | 4 | ILE A 82VAL A 67THR A 31ILE A 34 | None | 0.73A | 3p4wC-4to8A:undetectable | 3p4wC-4to8A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwu | INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE,INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH) | 4 | ILE A 478VAL A 43THR A 377ILE A 380 | None | 0.77A | 3p4wC-4xwuA:undetectable | 3p4wC-4xwuA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y07 | NEDD4-LIKE E3UBIQUITIN-PROTEINLIGASE WWP2 (Homo sapiens) |
PF00632(HECT) | 4 | ILE A 608VAL A 571THR A 624ILE A 622 | None | 0.67A | 3p4wC-4y07A:undetectable | 3p4wC-4y07A:18.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 4 | ILE A 208ILE A 209THR A 262ILE A 265 | None | 0.42A | 3p4wC-4yeuA:19.9 | 3p4wC-4yeuA:52.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 4 | PRO A 120ILE A 208ILE A 209THR A 262 | None | 0.82A | 3p4wC-4yeuA:19.9 | 3p4wC-4yeuA:52.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 4 | ILE A 152VAL A 101THR A 21ILE A 24 | None | 0.80A | 3p4wC-4zqgA:undetectable | 3p4wC-4zqgA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az4 | FLAGELLAR HOOKSUBUNIT PROTEIN (Campylobacterjejuni) |
PF07196(Flagellin_IN)PF07559(FlaE) | 4 | TYR A 484TYR A 516ILE A 531VAL A 556 | None | 0.86A | 3p4wC-5az4A:undetectable | 3p4wC-5az4A:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c4g | PHOSPHATIDYLINOSITOL4-KINASE BETA (Homo sapiens) |
PF00454(PI3_PI4_kinase) | 4 | TYR E 197ILE E 141ILE E 145ILE E 160 | None | 0.79A | 3p4wC-5c4gE:undetectable | 3p4wC-5c4gE:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 4 | PRO A 204TYR A 488ILE A 584ILE A 583 | None | 0.66A | 3p4wC-5djwA:undetectable | 3p4wC-5djwA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | SPINDLE POLE BODYCOMPONENT SPC98 (Saccharomycescerevisiae) |
PF04130(Spc97_Spc98) | 4 | TYR B 652ILE B 656ILE B 657ILE B 586 | None | 0.88A | 3p4wC-5flzB:4.0 | 3p4wC-5flzB:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 4 | TYR A 148ILE A 147VAL A 185ILE A 132 | GOL A1374 ( 4.6A)NoneNoneNone | 0.82A | 3p4wC-5g5nA:undetectable | 3p4wC-5g5nA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpz | WATER-SOLUBLECHLOROPHYLL PROTEIN (Brassicaceae) |
PF00197(Kunitz_legume) | 4 | TYR A 18ILE A 72ILE A 126ILE A 80 | None | 0.82A | 3p4wC-5hpzA:undetectable | 3p4wC-5hpzA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9t | PROTEIN TRANSLOCASESUBUNIT SECA (Escherichiacoli) |
PF01043(SecA_PP_bind)PF07517(SecA_DEAD) | 4 | ILE A 438ILE A 439VAL A 454ILE A 474 | None | 0.86A | 3p4wC-5k9tA:undetectable | 3p4wC-5k9tA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lv1 | PTXB (Prochlorococcusmarinus) |
no annotation | 4 | ILE A 105ILE A 104VAL A 167ILE A 118 | None | 0.63A | 3p4wC-5lv1A:undetectable | 3p4wC-5lv1A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mif | 'CARBOXYL ESTERASE 2 (Tubermelanosporum) |
PF07859(Abhydrolase_3) | 4 | ILE A 217VAL A 312THR A 334ILE A 335 | None | 0.85A | 3p4wC-5mifA:undetectable | 3p4wC-5mifA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT C (Methanothermococcusthermolithotrophicus) |
PF13183(Fer4_8) | 4 | ILE C 74ILE C 97VAL C 68ILE C 58 | NoneNoneNoneSF4 C 201 ( 4.8A) | 0.84A | 3p4wC-5odrC:undetectable | 3p4wC-5odrC:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol8 | TRANSCRIPTIONELONGATION FACTOR,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | TYR A 229ILE A 171ILE A 173ILE A 219 | None | 0.85A | 3p4wC-5ol8A:undetectable | 3p4wC-5ol8A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ola | TRANSCRIPTIONELONGATION FACTOR,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | TYR A 229ILE A 171ILE A 173ILE A 219 | None | 0.88A | 3p4wC-5olaA:undetectable | 3p4wC-5olaA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tc3 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH)PF00571(CBS) | 4 | ILE A 478VAL A 43THR A 377ILE A 380 | None | 0.79A | 3p4wC-5tc3A:undetectable | 3p4wC-5tc3A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tj7 | NEDD4-LIKE E3UBIQUITIN-PROTEINLIGASE WWP2 (Homo sapiens) |
PF00397(WW)PF00632(HECT) | 4 | ILE A 608VAL A 571THR A 624ILE A 622 | None | 0.73A | 3p4wC-5tj7A:2.5 | 3p4wC-5tj7A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5um8 | GLYCOPROTEIN GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 4 | ILE G 333ILE G 414VAL G 292ILE G 339 | None | 0.86A | 3p4wC-5um8G:undetectable | 3p4wC-5um8G:19.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5v6n | PROTON-GATED IONCHANNEL (Gloeobacterviolaceus) |
no annotation | 8 | TYR C 119PRO C 120TYR C 197ILE C 201ILE C 202VAL C 242THR C 255ILE C 258 | None | 0.41A | 3p4wC-5v6nC:36.1 | 3p4wC-5v6nC:98.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1x | MUTATOR MUTT PROTEIN (Staphylococcusaureus) |
PF00293(NUDIX) | 4 | PRO A 36ILE A 11ILE A 12ILE A 54 | None | 0.78A | 3p4wC-5x1xA:undetectable | 3p4wC-5x1xA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x4z | RNA POLYMERASESUBUNIT ABC14.5,COMMON TO RNAPOLYMERASES I, II,AND III (Komagataellaphaffii) |
PF03870(RNA_pol_Rpb8) | 4 | ILE H 26ILE H 42VAL H 12ILE H 143 | None | 0.85A | 3p4wC-5x4zH:undetectable | 3p4wC-5x4zH:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xoz | TRYPSIN PROTEININHIBITOR 2 (Cicer arietinum) |
no annotation | 4 | TYR A 29ILE A 82ILE A 137ILE A 90 | None | 0.82A | 3p4wC-5xozA:undetectable | 3p4wC-5xozA:11.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xuk | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Helicobacterpylori) |
no annotation | 4 | ILE A 82ILE A 72VAL A 112ILE A 101 | NoneNoneNoneCOA A 201 (-3.9A) | 0.81A | 3p4wC-5xukA:undetectable | 3p4wC-5xukA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bni | LYSINE--TRNA LIGASE (Cryptosporidiumparvum) |
no annotation | 4 | TYR A 345ILE A 357ILE A 343VAL A 460 | None | 0.71A | 3p4wC-6bniA:undetectable | 3p4wC-6bniA:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evj | RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Avirus) |
no annotation | 4 | TYR B 555ILE B 552THR B 527ILE B 530 | None | 0.83A | 3p4wC-6evjB:undetectable | 3p4wC-6evjB:13.21 |