SIMILAR PATTERNS OF AMINO ACIDS FOR 3P2K_A_SAMA6735_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN

(Mus musculus) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASP A 156
GLU A  87
SER A 189
 None
 0.86A 3p2kA-1f3bA:
undetectable		 3p2kA-1f3bA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kh2 ARGININOSUCCINATE
SYNTHETASE

(Thermus
thermophilus) 		PF00764
(Arginosuc_synth) 		3 ASP A 121
GLU A 258
SER A   8
 None
None
ATP  A 510 (-2.2A)
 0.82A 3p2kA-1kh2A:
undetectable		 3p2kA-1kh2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E

(Enterococcus
faecalis) 		PF01636
(APH) 		3 ASP A 261
GLU A 142
SER A 227
 KAN  A   1 (-3.8A)
None
KAN  A   1 (-4.3A)
 0.79A 3p2kA-1l8tA:
undetectable		 3p2kA-1l8tA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rk2 RIBOKINASE

(Escherichia
coli) 		PF00294
(PfkB) 		3 ASP A  80
GLU A 300
SER A  72
 None
 0.74A 3p2kA-1rk2A:
4.2		 3p2kA-1rk2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 40 KDA
SUBUNIT
ACTIVATOR 1 41 KDA
SUBUNIT

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08542
(Rep_fac_C)
PF00004
(AAA)
PF08542
(Rep_fac_C) 		3 ASP D 330
GLU D 339
SER C 321
 None
 0.70A 3p2kA-1sxjD:
undetectable		 3p2kA-1sxjD:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl2 ARGININOSUCCINATE
SYNTHASE

(Thermotoga
maritima) 		PF00764
(Arginosuc_synth) 		3 ASP A 122
GLU A 268
SER A  10
 None
 0.80A 3p2kA-1vl2A:
undetectable		 3p2kA-1vl2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wxx HYPOTHETICAL PROTEIN
TTHA1280

(Thermus
thermophilus) 		PF10672
(Methyltrans_SAM) 		3 ASP A 197
GLU A 177
SER A 327
 None
 0.78A 3p2kA-1wxxA:
9.7		 3p2kA-1wxxA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfj DNA ADENINE
METHYLASE

(Escherichia
virus T4) 		PF02086
(MethyltransfD12) 		3 ASP A 171
GLU A 190
SER A  13
 SAH  A 401 (-3.8A)
None
None
 0.53A 3p2kA-1yfjA:
5.0		 3p2kA-1yfjA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5v L-ASPARTATE OXIDASE

(Sulfurisphaera
tokodaii) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ASP A 191
GLU A 157
SER A 176
 FAD  A1002 (-2.9A)
None
None
 0.81A 3p2kA-2e5vA:
2.8		 3p2kA-2e5vA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ek8 AMINOPEPTIDASE

(Aneurinibacillus
sp. AM-1) 		PF02225
(PA)
PF04389
(Peptidase_M28) 		3 ASP A 241
GLU A 367
SER A 279
 ZN  A1002 ( 4.7A)
None
None
 0.81A 3p2kA-2ek8A:
undetectable		 3p2kA-2ek8A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ASP A 445
GLU A  69
SER A 185
 None
 0.78A 3p2kA-2g3nA:
undetectable		 3p2kA-2g3nA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g8l 287AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF01937
(DUF89) 		3 ASP A 156
GLU A 246
SER A  78
 UNL  A 288 (-3.1A)
None
None
 0.81A 3p2kA-2g8lA:
3.6		 3p2kA-2g8lA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i4n PROLINE-TRNA LIGASE

(Rhodopseudomonas
palustris) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		3 ASP A 159
GLU A 112
SER A 321
 None
None
5CA  A 439 ( 4.3A)
 0.82A 3p2kA-2i4nA:
undetectable		 3p2kA-2i4nA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe7 ATP SYNTHASE SUBUNIT
BETA

(Bacillus sp.
TA2.A1) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		3 ASP D 319
GLU D 283
SER D 348
 None
 0.82A 3p2kA-2qe7D:
2.5		 3p2kA-2qe7D:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjo BIFUNCTIONAL NMN
ADENYLYLTRANSFERASE/
NUDIX HYDROLASE

(Synechocystis
sp. PCC 6803) 		PF00293
(NUDIX)
PF01467
(CTP_transf_like) 		3 ASP A  80
GLU A 322
SER A 116
 NAD  A 601 (-2.8A)
None
NAD  A 601 ( 4.4A)
 0.73A 3p2kA-2qjoA:
2.8		 3p2kA-2qjoA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qo3 ERYAII ERYTHROMYCIN
POLYKETIDE SYNTHASE
MODULES 3 AND 4

(Saccharopolyspora
erythraea) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ASP A 118
GLU A 160
SER A 182
 None
 0.83A 3p2kA-2qo3A:
undetectable		 3p2kA-2qo3A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn4 ADP-RIBOSYLTRANSFERA
SE ENZYMATIC
COMPONENT

(Clostridioides
difficile) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 219
GLU A 187
SER A 347
 None
 0.76A 3p2kA-2wn4A:
undetectable		 3p2kA-2wn4A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpz LEUKOTRIENE A-4
HYDROLASE

(Saccharomyces
cerevisiae) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		3 ASP A 109
GLU A 130
SER A 201
 None
 0.63A 3p2kA-2xpzA:
undetectable		 3p2kA-2xpzA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfk ASPARTATE/ORNITHINE
CARBAMOYLTRANSFERASE

(Enterococcus
faecalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ASP A  43
GLU A   6
SER A 362
 None
 0.78A 3p2kA-2yfkA:
4.3		 3p2kA-2yfkA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdb NOVEL IMMUNE-TYPE
RECEPTOR 11

(Ictalurus
punctatus) 		PF07686
(V-set) 		3 ASP A  87
GLU A 112
SER A  68
 None
 0.55A 3p2kA-3bdbA:
undetectable		 3p2kA-3bdbA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bol 5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE

(Thermotoga
maritima) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		3 ASP A 358
GLU A 364
SER A 534
 None
 0.83A 3p2kA-3bolA:
undetectable		 3p2kA-3bolA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buz IOTA TOXIN COMPONENT
IA

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A 212
GLU A 180
SER A 340
 None
 0.75A 3p2kA-3buzA:
undetectable		 3p2kA-3buzA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czm L-LACTATE
DEHYDROGENASE

(Toxoplasma
gondii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ASP A 111
GLU A 324
SER A 103
 None
 0.82A 3p2kA-3czmA:
4.8		 3p2kA-3czmA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoj BACTERIOCHLOROPHYLL
A PROTEIN

(Prosthecochloris
aestuarii) 		PF02327
(BChl_A) 		3 ASP A 146
GLU A  90
SER A 207
 None
 0.55A 3p2kA-3eojA:
undetectable		 3p2kA-3eojA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fsg ALPHA/BETA
SUPERFAMILY
HYDROLASE

(Oenococcus oeni) 		PF12697
(Abhydrolase_6) 		3 ASP A 216
GLU A 223
SER A 155
 None
 0.83A 3p2kA-3fsgA:
2.9		 3p2kA-3fsgA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iir TRYPSIN INHIBITOR

(Murraya
koenigii) 		PF00197
(Kunitz_legume) 		3 ASP A  94
GLU A  87
SER A  99
 None
 0.80A 3p2kA-3iirA:
undetectable		 3p2kA-3iirA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9u V-TYPE PROTON ATPASE
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 3 ASP C 545
GLU C 593
SER C 552
 None
 0.78A 3p2kA-3j9uC:
undetectable		 3p2kA-3j9uC:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsz GLUTATHIONE
S-TRANSFERASE

(Rhodobacter
sphaeroides) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASP A 171
GLU A  98
SER A 203
 None
 0.82A 3p2kA-3lszA:
undetectable		 3p2kA-3lszA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mml ALLOPHANATE
HYDROLASE SUBUNIT 2

(Mycolicibacterium
smegmatis) 		PF02626
(CT_A_B) 		3 ASP A  36
GLU A 266
SER A 111
 None
 0.83A 3p2kA-3mmlA:
undetectable		 3p2kA-3mmlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwc MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Kosmotoga
olearia) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 337
GLU A 261
SER A 173
 None
MG  A 400 ( 4.0A)
None
 0.67A 3p2kA-3mwcA:
undetectable		 3p2kA-3mwcA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Clostridium
perfringens) 		PF14010
(PEPcase_2) 		3 ASP A 202
GLU A 126
SER A 393
 None
 0.82A 3p2kA-3odmA:
undetectable		 3p2kA-3odmA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogk CORONATINE-INSENSITI
VE PROTEIN 1

(Arabidopsis
thaliana) 		no annotation 3 ASP B 331
GLU B 361
SER B 394
 None
 0.72A 3p2kA-3ogkB:
undetectable		 3p2kA-3ogkB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozy PUTATIVE MANDELATE
RACEMASE

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 331
GLU A 158
SER A  53
 None
 0.86A 3p2kA-3ozyA:
undetectable		 3p2kA-3ozyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		3 ASP A 511
GLU A 392
SER A 490
 None
 0.82A 3p2kA-3pf2A:
undetectable		 3p2kA-3pf2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppc 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Candida
albicans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		3 ASP A 504
GLU A 499
SER A 526
 None
 0.69A 3p2kA-3ppcA:
undetectable		 3p2kA-3ppcA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5e TRANSALDOLASE

(Corynebacterium
glutamicum) 		PF00923
(TAL_FSA) 		3 ASP A  83
GLU A 108
SER A  26
 None
 0.75A 3p2kA-3r5eA:
1.8		 3p2kA-3r5eA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT

(uncultured
archaeon) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		3 ASP A 359
GLU A 366
SER A  15
 None
 0.67A 3p2kA-3sqgA:
undetectable		 3p2kA-3sqgA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		3 ASP A 526
GLU A 600
SER A 453
 None
 0.83A 3p2kA-3t6qA:
2.0		 3p2kA-3t6qA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqp ENOLASE

(Coxiella
burnetii) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		3 ASP A  84
GLU A  89
SER A  30
 None
 0.56A 3p2kA-3tqpA:
undetectable		 3p2kA-3tqpA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vns NRPS ADENYLATION
PROTEIN CYTC1

(Streptomyces
sp.) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ASP A 401
GLU A 311
SER A 331
 AMP  A 601 (-2.7A)
None
None
 0.77A 3p2kA-3vnsA:
undetectable		 3p2kA-3vnsA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Sulfurisphaera
tokodaii) 		PF08443
(RimK) 		3 ASP A 176
GLU A 198
SER A 235
 ADP  A 500 (-2.6A)
None
None
 0.85A 3p2kA-3vpcA:
2.4		 3p2kA-3vpcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w8s GLUTATHIONE
S-TRANSFERASE-3

(Necator
americanus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		3 ASP A 157
GLU A  84
SER A 190
 None
 0.81A 3p2kA-3w8sA:
undetectable		 3p2kA-3w8sA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9y DISKS LARGE HOMOLOG
1

(Homo sapiens) 		PF00625
(Guanylate_kin) 		3 ASP A 794
GLU A 789
SER A 817
 None
 0.79A 3p2kA-3w9yA:
undetectable		 3p2kA-3w9yA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus) 		PF02516
(STT3) 		3 ASP A 302
GLU A 307
SER A 247
 None
 0.85A 3p2kA-3wajA:
undetectable		 3p2kA-3wajA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wkh CELLOBIOSE
2-EPIMERASE

(Rhodothermus
marinus) 		PF07221
(GlcNAc_2-epim) 		3 ASP A 383
GLU A 365
SER A 185
 None
None
GAL  A 503 (-3.2A)
 0.58A 3p2kA-3wkhA:
undetectable		 3p2kA-3wkhA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyn LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4B

(Mus musculus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		3 ASP A 190
GLU A 235
SER A 120
 None
 0.83A 3p2kA-3zynA:
undetectable		 3p2kA-3zynA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyo LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4B

(Mus musculus) 		PF00560
(LRR_1)
PF07679
(I-set)
PF13855
(LRR_8) 		3 ASP A 190
GLU A 235
SER A 120
 None
 0.85A 3p2kA-3zyoA:
undetectable		 3p2kA-3zyoA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8j ELONGATOR COMPLEX
PROTEIN 5

(Saccharomyces
cerevisiae) 		PF10483
(Elong_Iki1) 		3 ASP B 172
GLU B 217
SER B 185
 None
 0.81A 3p2kA-4a8jB:
undetectable		 3p2kA-4a8jB:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az3 LYSOSOMAL PROTECTIVE
PROTEIN 32 KDA CHAIN
LYSOSOMAL PROTECTIVE
PROTEIN 20 KDA CHAIN

(Homo sapiens;
Homo sapiens) 		PF00450
(Peptidase_S10)
PF00450
(Peptidase_S10) 		3 ASP B 372
GLU A  69
SER A 189
 None
 0.69A 3p2kA-4az3B:
undetectable		 3p2kA-4az3B:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bi9 3-KETOACYL-COA
THIOLASE, PUTATIVE

(Trypanosoma
brucei) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		3 ASP A 254
GLU A 342
SER A 234
 None
 0.85A 3p2kA-4bi9A:
undetectable		 3p2kA-4bi9A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3

(Homo sapiens;
Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2)
PF00362
(Integrin_beta)
PF07965
(Integrin_B_tail)
PF07974
(EGF_2)
PF17205
(PSI_integrin) 		3 ASP A 560
GLU B  55
SER B 385
 None
None
NAG  B3452 ( 4.9A)
 0.85A 3p2kA-4cakA:
undetectable		 3p2kA-4cakA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvg RHO-LIKE SMALL
GTPASE
DIAPHANOUS PROTEIN

(Entamoeba
histolytica;
Entamoeba
histolytica) 		PF00071
(Ras)
PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASP B 238
GLU A  79
SER B 297
 None
 0.61A 3p2kA-4dvgB:
undetectable		 3p2kA-4dvgB:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzc EPSIN-2

(Saccharomyces
cerevisiae) 		PF01417
(ENTH) 		3 ASP A  57
GLU A  97
SER A  17
 None
None
CL  A 201 ( 4.9A)
 0.83A 3p2kA-4gzcA:
undetectable		 3p2kA-4gzcA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h41 PUTATIVE
ALPHA-L-FUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF14488
(DUF4434)
PF17134
(DUF5109) 		3 ASP A  66
GLU A 191
SER A 347
 None
UNL  A 401 ( 3.2A)
None
 0.72A 3p2kA-4h41A:
undetectable		 3p2kA-4h41A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h63 MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 17

(Schizosaccharomyces
pombe) 		PF10156
(Med17) 		3 ASP Q 124
GLU Q 118
SER Q 147
 None
 0.85A 3p2kA-4h63Q:
undetectable		 3p2kA-4h63Q:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igi COLLAGEN ALPHA3(VI)

(Mus musculus) 		PF00092
(VWA) 		3 ASP A1032
GLU A1171
SER A1039
 None
 0.80A 3p2kA-4igiA:
undetectable		 3p2kA-4igiA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Ruegeria sp.
TM1040) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A  21
GLU A 387
SER A 196
 None
 0.83A 3p2kA-4ip4A:
0.9		 3p2kA-4ip4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4khb UNCHARACTERIZED
PROTEIN SPT16D
UNCHARACTERIZED
PROTEIN POB3N

(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		PF08644
(SPT16)
no annotation 		3 ASP D   8
GLU D   5
SER A 576
 None
 0.77A 3p2kA-4khbD:
undetectable		 3p2kA-4khbD:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwt LYSOSOMAL PROTECTIVE
PROTEIN

(Homo sapiens) 		PF00450
(Peptidase_S10) 		3 ASP A 372
GLU A  69
SER A 189
 ASP  A 372 ( 0.6A)
GLU  A  69 ( 0.5A)
SER  A 189 ( 0.0A)
 0.70A 3p2kA-4mwtA:
undetectable		 3p2kA-4mwtA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7r GLUTAMYL-TRNA
REDUCTASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00745
(GlutR_dimer)
PF01488
(Shikimate_DH)
PF05201
(GlutR_N) 		3 ASP A 438
GLU A 514
SER A  96
 None
 0.82A 3p2kA-4n7rA:
4.7		 3p2kA-4n7rA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nhw GLUTATHIONE
S-TRANSFERASE

(Sinorhizobium
meliloti) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		3 ASP A 171
GLU A  98
SER A 203
 None
 0.77A 3p2kA-4nhwA:
undetectable		 3p2kA-4nhwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1e DIHYDROPTEROATE
SYNTHASE DHPS

(Desulfitobacterium
hafniense) 		PF00809
(Pterin_bind) 		3 ASP A  44
GLU A  54
SER A 225
 None
 0.70A 3p2kA-4o1eA:
undetectable		 3p2kA-4o1eA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1

(Homo sapiens;
Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		3 ASP A 262
GLU A 315
SER B  99
 None
None
GCP  B 701 ( 4.2A)
 0.70A 3p2kA-4p4sA:
undetectable		 3p2kA-4p4sA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1

(Homo sapiens;
Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		3 ASP B 262
GLU B 315
SER A  99
 None
None
GCP  A 401 ( 4.4A)
 0.72A 3p2kA-4p4sB:
undetectable		 3p2kA-4p4sB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdh VARIABLE LYMPHOCYTE
RECEPTOR B,
TOLL-LIKE RECEPTOR 9
CHIMERA

(Eptatretus
burgeri;
Mus musculus) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13306
(LRR_5)
PF13855
(LRR_8) 		3 ASP A 287
GLU A 334
SER A 216
 NAG  A 505 ( 4.6A)
NAG  A 505 ( 4.5A)
None
 0.63A 3p2kA-4qdhA:
undetectable		 3p2kA-4qdhA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6g LEUCINE RICH REPEATS
DLRR_K

(synthetic
construct) 		PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		3 ASP A 371
GLU A 454
SER A 292
 None
 0.82A 3p2kA-4r6gA:
undetectable		 3p2kA-4r6gA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry9 PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Verminephrobacter
eiseniae) 		PF13407
(Peripla_BP_4) 		3 ASP A 260
GLU A 264
SER A 124
 TLZ  A 401 ( 2.7A)
None
TLZ  A 401 (-2.8A)
 0.73A 3p2kA-4ry9A:
undetectable		 3p2kA-4ry9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8u GLOBIN C CHAIN
LINKER L1

(Glossoscolex
paulistus;
Glossoscolex
paulistus) 		PF00042
(Globin)
PF16915
(Eryth_link_C) 		3 ASP C  84
GLU M  66
SER C   6
 None
 0.85A 3p2kA-4u8uC:
undetectable		 3p2kA-4u8uC:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uw9 BETA-PHOSPHOGLUCOMUT
ASE

(Pyrococcus sp.
ST04) 		PF13419
(HAD_2) 		3 ASP A 179
GLU A 100
SER A  42
 MG  A1229 (-4.7A)
None
None
 0.86A 3p2kA-4uw9A:
2.2		 3p2kA-4uw9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		PF01425
(Amidase)
PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		3 ASP B 277
GLU B 126
SER A 197
 None
 0.85A 3p2kA-4wj3B:
undetectable		 3p2kA-4wj3B:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z42 UREASE SUBUNIT ALPHA

(Yersinia
enterocolitica) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 ASP C  79
GLU C  33
SER C 423
 None
 0.73A 3p2kA-4z42C:
undetectable		 3p2kA-4z42C:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		3 ASP A 328
GLU A 411
SER A 383
 None
 0.79A 3p2kA-5a29A:
undetectable		 3p2kA-5a29A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9b POLYHEDRIN

(Cypovirus 1) 		PF05865
(Cypo_polyhedrin) 		3 ASP A  45
GLU A 219
SER A 102
 None
 0.78A 3p2kA-5a9bA:
undetectable		 3p2kA-5a9bA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bth DECAPPING NUCLEASE
RAI1

(Candida
albicans) 		PF08652
(RAI1) 		3 ASP A 121
GLU A 146
SER A 362
 None
 0.81A 3p2kA-5bthA:
undetectable		 3p2kA-5bthA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgk ACTIVE HELICASE

(Staphylococcus
aureus) 		PF06048
(DUF927) 		3 ASP A 321
GLU A 388
SER A 317
 None
 0.81A 3p2kA-5dgkA:
undetectable		 3p2kA-5dgkA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlq EXPORTIN-4

(Mus musculus) 		no annotation 3 ASP B 476
GLU B 468
SER B 349
 None
 0.61A 3p2kA-5dlqB:
undetectable		 3p2kA-5dlqB:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ASP A 395
GLU A 184
SER A 400
 M2A  A 501 (-2.7A)
M2A  A 501 (-3.6A)
None
 0.84A 3p2kA-5elxA:
3.1		 3p2kA-5elxA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4e IZUMO SPERM-EGG
FUSION PROTEIN 1

(Homo sapiens) 		PF15005
(IZUMO)
PF16706
(Izumo-Ig) 		3 ASP A  93
GLU A 120
SER A 100
 None
 0.75A 3p2kA-5f4eA:
undetectable		 3p2kA-5f4eA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjv VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S

(Oryctolagus
cuniculus) 		PF00520
(Ion_trans)
PF08763
(Ca_chan_IQ)
PF16905
(GPHH) 		3 ASP A 662
GLU A 668
SER A 561
 None
 0.76A 3p2kA-5gjvA:
undetectable		 3p2kA-5gjvA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gmh TOLL-LIKE RECEPTOR 7

(Macaca mulatta) 		PF00560
(LRR_1)
PF13306
(LRR_5)
PF13855
(LRR_8) 		3 ASP A 548
GLU A 625
SER A 429
 NAG  A 902 (-3.9A)
None
NAG  A 902 ( 4.2A)
 0.63A 3p2kA-5gmhA:
undetectable		 3p2kA-5gmhA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqr LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE TDR

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		3 ASP B 447
GLU B 518
SER B 377
 None
 0.86A 3p2kA-5gqrB:
undetectable		 3p2kA-5gqrB:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		3 ASP A 694
GLU A 768
SER A 616
 None
 0.60A 3p2kA-5hdhA:
undetectable		 3p2kA-5hdhA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k6o B-GLUCOSIDASE

(metagenome) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ASP A 365
GLU A 378
SER A 419
 None
 0.55A 3p2kA-5k6oA:
undetectable		 3p2kA-5k6oA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE ALPHA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		3 ASP b 245
GLU b 511
SER b 306
 None
 0.78A 3p2kA-5l9wb:
undetectable		 3p2kA-5l9wb:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n86 STABILIN-2

(Homo sapiens) 		no annotation 3 ASP A  65
GLU A  59
SER A  93
 None
 0.83A 3p2kA-5n86A:
undetectable		 3p2kA-5n86A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9x ADENYLATION DOMAIN

(Streptomyces
sp.) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ASP A 406
GLU A 315
SER A 335
 ATP  A 602 (-2.7A)
ATP  A 602 (-3.4A)
ATP  A 602 ( 4.8A)
 0.84A 3p2kA-5n9xA:
undetectable		 3p2kA-5n9xA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 3 ASP A 313
GLU A 142
SER A 273
 8U8  A 712 (-3.6A)
None
None
 0.85A 3p2kA-5ndxA:
undetectable		 3p2kA-5ndxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubp LEUCINE PERMEASE
TRANSCRIPTIONAL
REGULATOR

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		3 ASP A 192
GLU A 117
SER A 186
 None
 0.69A 3p2kA-5ubpA:
undetectable		 3p2kA-5ubpA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5un1 N-METHYL-D-ASPARTATE
RECEPTOR SUBUNIT
NR1-3A

(Xenopus laevis) 		no annotation 3 ASP G 509
GLU G 502
SER G 395
 None
 0.67A 3p2kA-5un1G:
undetectable		 3p2kA-5un1G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz4 SMALL RIBOSOMAL
SUBUNIT BIOGENESIS
GTPASE RSGA

(Escherichia
coli) 		PF03193
(RsgA_GTPase) 		3 ASP Z  77
GLU Z 102
SER Z 267
 None
None
G  A1494 ( 4.5A)
 0.82A 3p2kA-5uz4Z:
2.5		 3p2kA-5uz4Z:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xun ACETYLTRANSFERASE

(Klebsiella
pneumoniae) 		PF13673
(Acetyltransf_10) 		3 ASP A 100
GLU A  26
SER A  52
 None
 0.86A 3p2kA-5xunA:
undetectable		 3p2kA-5xunA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyn PLATINUM SENSITIVITY
PROTEIN 3

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A 220
GLU A 169
SER A  34
 None
 0.85A 3p2kA-5xynA:
undetectable		 3p2kA-5xynA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 3 ASP A 314
GLU A 368
SER A 228
 None
 0.62A 3p2kA-5y3jA:
undetectable		 3p2kA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 3 ASP A 683
GLU A 729
SER A 606
 None
 0.75A 3p2kA-5y3jA:
undetectable		 3p2kA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 3 ASP A 314
GLU A 368
SER A 228
 None
 0.67A 3p2kA-5zlnA:
undetectable		 3p2kA-5zlnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 3 ASP A 684
GLU A 730
SER A 607
 None
 0.76A 3p2kA-5zlnA:
undetectable		 3p2kA-5zlnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bq1 PHOSPHATIDYLINOSITOL
4-KINASE III ALPHA
(PI4KA)

(Homo sapiens) 		no annotation 3 ASP A1300
GLU A1235
SER A1405
 None
 0.85A 3p2kA-6bq1A:
undetectable		 3p2kA-6bq1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byo VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S

(Oryctolagus
cuniculus) 		no annotation 3 ASP A 662
GLU A 668
SER A 561
 None
 0.77A 3p2kA-6byoA:
undetectable		 3p2kA-6byoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eks SIALIDASE

(Vibrio cholerae) 		no annotation 3 ASP A 318
GLU A 782
SER A 569
 G39  A 908 ( 4.2A)
None
None
 0.67A 3p2kA-6eksA:
undetectable		 3p2kA-6eksA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A 940
GLU A 644
SER A1066
 None
 0.80A 3p2kA-6f42A:
undetectable		 3p2kA-6f42A:
undetectable