SIMILAR PATTERNS OF AMINO ACIDS FOR 3P0K_A_ACTA267

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		5 VAL A 149
ARG A 159
TYR A 162
MET A 163
LYS A 166
 None
None
FAD  A 334 ( 4.2A)
None
None
 0.61A 3p0kA-3qzyA:
33.3		 3p0kA-3qzyA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh6 CENP-T

(Gallus gallus) 		PF15511
(CENP-T_C) 		4 VAL T 553
ARG T 555
TYR T 558
LYS T 542
 None
 1.38A 3p0kA-3vh6T:
undetectable		 3p0kA-3vh6T:
17.32