SIMILAR PATTERNS OF AMINO ACIDS FOR 3OZW_A_KKKA413_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bk6 KARYOPHERIN ALPHA

(Saccharomyces
cerevisiae) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 ILE A 357
GLN A 316
ALA A 319
LEU A 320
 None
 0.66A 3ozwA-1bk6A:
undetectable		 3ozwA-1bk6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgj ALDEHYDE
OXIDOREDUCTASE

(Desulfovibrio
desulfuricans) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		4 ILE A 225
ALA A 213
LEU A 282
LEU A 304
 None
 0.84A 3ozwA-1dgjA:
undetectable		 3ozwA-1dgjA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ekb ENTEROPEPTIDASE

(Bos taurus) 		PF00089
(Trypsin) 		4 ILE B 121
GLN B 202
ALA B 210
LEU B 209
 None
 0.82A 3ozwA-1ekbB:
undetectable		 3ozwA-1ekbB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1es6 MATRIX PROTEIN VP40

(Ebola virus sp.) 		PF07447
(VP40) 		4 ILE A 252
GLN A 282
LEU A 186
LEU A 288
 None
 0.83A 3ozwA-1es6A:
undetectable		 3ozwA-1es6A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ewk METABOTROPIC
GLUTAMATE RECEPTOR
SUBTYPE 1

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 GLN A 425
ALA A 421
LEU A 424
LEU A 438
 None
 0.83A 3ozwA-1ewkA:
5.0		 3ozwA-1ewkA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5q GAMMA HERPESVIRUS
CYCLIN

(Murid
gammaherpesvirus
4) 		PF00134
(Cyclin_N) 		4 ILE B 224
GLN B 231
ALA B 198
LEU B 197
 None
 0.73A 3ozwA-1f5qB:
undetectable		 3ozwA-1f5qB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp9 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
thermophilus) 		PF02446
(Glyco_hydro_77) 		4 GLN A 195
ALA A 198
LEU A 199
LEU A  16
 None
 0.85A 3ozwA-1fp9A:
undetectable		 3ozwA-1fp9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT

(Klebsiella
pneumoniae) 		PF02286
(Dehydratase_LU) 		4 ILE A 474
ALA A 184
LEU A 188
LEU A 494
 None
 0.87A 3ozwA-1iwpA:
undetectable		 3ozwA-1iwpA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 ILE A 256
ALA A 208
LEU A 207
LEU A 186
 None
 0.79A 3ozwA-1jx2A:
undetectable		 3ozwA-1jx2A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkp MAX PROTEIN
MYC PROTO-ONCOGENE
PROTEIN

(Homo sapiens) 		PF00010
(HLH)
PF02344
(Myc-LZ) 		4 ILE A 942
ALA A 923
LEU A 924
LEU B 225
 None
 0.84A 3ozwA-1nkpA:
undetectable		 3ozwA-1nkpA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		4 ILE A1002
ALA A 962
LEU A 963
LEU A1024
 None
 0.87A 3ozwA-1no7A:
undetectable		 3ozwA-1no7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3t CYTIDYLATE KINASE

(Streptococcus
pneumoniae) 		PF02224
(Cytidylate_kin) 		4 ILE A 138
GLN A 130
GLN A  18
ALA A  20
 None
 0.82A 3ozwA-1q3tA:
undetectable		 3ozwA-1q3tA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1slj RIBONUCLEASE E

(Escherichia
coli) 		PF00575
(S1) 		4 ILE A  73
ALA A  56
LEU A  68
LEU A 122
 None
 0.80A 3ozwA-1sljA:
2.8		 3ozwA-1sljA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t82 HYPOTHETICAL
ACETYLTRANSFERASE

(Shewanella
oneidensis) 		PF09500
(YiiD_C) 		4 ILE A  55
GLN A 134
ALA A  91
LEU A  40
 None
 0.81A 3ozwA-1t82A:
undetectable		 3ozwA-1t82A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vkw PUTATIVE
NITROREDUCTASE

(Thermotoga
maritima) 		PF14512
(TM1586_NiRdase) 		4 ILE A 136
LEU A 161
LEU A 129
PRO A 206
 None
 0.79A 3ozwA-1vkwA:
undetectable		 3ozwA-1vkwA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w98 G1/S-SPECIFIC CYCLIN
E1

(Homo sapiens) 		PF00134
(Cyclin_N)
PF02984
(Cyclin_C) 		4 TYR B 281
GLN B 155
ALA B 154
LEU B 153
 None
 0.85A 3ozwA-1w98B:
undetectable		 3ozwA-1w98B:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 ILE B 357
GLN B 316
ALA B 319
LEU B 320
 None
 0.55A 3ozwA-1wa5B:
undetectable		 3ozwA-1wa5B:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wqa PHOSPHO-SUGAR MUTASE

(Pyrococcus
horikoshii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A  98
ALA A  60
LEU A  61
LEU A 112
 ILE  A  98 ( 0.7A)
ALA  A  60 ( 0.0A)
LEU  A  61 ( 0.6A)
LEU  A 112 ( 0.6A)
 0.76A 3ozwA-1wqaA:
undetectable		 3ozwA-1wqaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afg ACIDIC FIBROBLAST
GROWTH FACTOR

(Homo sapiens) 		PF00167
(FGF) 		4 ILE A  25
GLN A  77
ALA A  66
LEU A  65
 None
 0.87A 3ozwA-2afgA:
undetectable		 3ozwA-2afgA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2apo PROBABLE TRNA
PSEUDOURIDINE
SYNTHASE B

(Methanocaldococcus
jannaschii) 		PF01472
(PUA)
PF01509
(TruB_N)
PF08068
(DKCLD)
PF16198
(TruB_C_2) 		4 ILE A  68
LEU A 218
LEU A  92
PRO A  53
 None
 0.75A 3ozwA-2apoA:
undetectable		 3ozwA-2apoA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csg PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF07350
(DUF1479) 		4 GLN A 219
GLN A 218
LEU A 213
LEU A 302
 None
 0.83A 3ozwA-2csgA:
undetectable		 3ozwA-2csgA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dg8 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATORY PROTEIN

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 ILE A 177
GLN A 146
ALA A 149
LEU A 150
 None
 0.76A 3ozwA-2dg8A:
undetectable		 3ozwA-2dg8A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drq XYLANASE Y

(Bacillus
halodurans) 		PF01270
(Glyco_hydro_8) 		4 ILE A 291
ALA A 241
LEU A 240
PRO A 196
 None
 0.83A 3ozwA-2drqA:
undetectable		 3ozwA-2drqA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hiv THERMOSTABLE DNA
LIGASE

(Sulfolobus
solfataricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 ILE A  16
GLN A  21
ALA A  24
LEU A  25
 None
 0.50A 3ozwA-2hivA:
undetectable		 3ozwA-2hivA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijc HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF02627
(CMD) 		4 ILE A  35
TYR A  39
ALA A  28
LEU A  30
 None
 0.83A 3ozwA-2ijcA:
undetectable		 3ozwA-2ijcA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivd PROTOPORPHYRINOGEN
OXIDASE

(Myxococcus
xanthus) 		PF01593
(Amino_oxidase) 		4 ILE A 426
TYR A 443
ALA A 300
LEU A 299
 None
 0.86A 3ozwA-2ivdA:
3.2		 3ozwA-2ivdA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjq UNCHARACTERIZED RNA
METHYLTRANSFERASE
PYRAB10780

(Pyrococcus
abyssi) 		PF05958
(tRNA_U5-meth_tr) 		4 ILE A 120
ALA A 147
LEU A 151
LEU A 172
 None
 0.84A 3ozwA-2jjqA:
5.2		 3ozwA-2jjqA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l25 UNCHARACTERIZED
PROTEIN

(Bordetella
bronchiseptica) 		PF13554
(DUF4128) 		4 ILE A 130
ALA A  89
LEU A  91
LEU A  44
 None
 0.82A 3ozwA-2l25A:
undetectable		 3ozwA-2l25A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o4d HYPOTHETICAL PROTEIN
PA0269

(Pseudomonas
aeruginosa) 		PF02627
(CMD) 		4 ILE A  35
TYR A  39
ALA A  28
LEU A  30
 None
 0.80A 3ozwA-2o4dA:
undetectable		 3ozwA-2o4dA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 4 ILE A 582
GLN A1082
GLN A1083
LEU A 590
 None
 0.73A 3ozwA-2po4A:
undetectable		 3ozwA-2po4A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 4 ILE A 777
GLN A 781
ALA A 784
LEU A 785
 None
 0.69A 3ozwA-2po4A:
undetectable		 3ozwA-2po4A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2raf PUTATIVE
DINUCLEOTIDE-BINDING
OXIDOREDUCTASE

(Lactobacillus
plantarum) 		PF03807
(F420_oxidored) 		4 GLN A  95
ALA A  91
LEU A  94
LEU A  62
 None
 0.87A 3ozwA-2rafA:
undetectable		 3ozwA-2rafA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ALA B  70
LEU B  72
LEU A  50
PRO A  18
 None
 0.72A 3ozwA-2v4jB:
undetectable		 3ozwA-2v4jB:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3c GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Homo sapiens) 		PF04869
(Uso1_p115_head) 		4 ILE A 584
GLN A 535
ALA A 542
LEU A 543
 None
 0.74A 3ozwA-2w3cA:
undetectable		 3ozwA-2w3cA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyx BETA-LACTAMSE TOHO-1

(Escherichia
coli) 		PF13354
(Beta-lactamase2) 		4 ILE A 285
GLN A  32
ALA A  35
LEU A  36
 None
 0.60A 3ozwA-2wyxA:
undetectable		 3ozwA-2wyxA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x1i 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
brockianus) 		PF02446
(Glyco_hydro_77) 		4 GLN A 195
ALA A 198
LEU A 199
LEU A  16
 None
 0.77A 3ozwA-2x1iA:
undetectable		 3ozwA-2x1iA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 ILE A 145
GLN A  28
LEU A 114
LEU A 207
 None
 0.86A 3ozwA-2zwaA:
undetectable		 3ozwA-2zwaA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3j PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Escherichia
coli) 		PF01380
(SIS) 		4 ILE A  20
GLN A 347
ALA A 350
LEU A 351
 None
 0.70A 3ozwA-3c3jA:
5.2		 3ozwA-3c3jA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c87 ENTEROCHELIN
ESTERASE

(Shigella
flexneri) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 TYR A 308
ALA A 290
LEU A 292
LEU A 359
 None
 0.77A 3ozwA-3c87A:
undetectable		 3ozwA-3c87A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddn D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00389
(2-Hacid_dh)
PF01842
(ACT)
PF02826
(2-Hacid_dh_C) 		4 ILE A 227
GLN A 274
LEU A 111
PRO A 119
 None
 0.85A 3ozwA-3ddnA:
2.2		 3ozwA-3ddnA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhn PROTEIN TRANSPORT
PROTEIN TIP20

(Saccharomyces
cerevisiae) 		PF04437
(RINT1_TIP1) 		4 GLN A 452
GLN A 456
ALA A 459
LEU A 439
 None
 0.70A 3ozwA-3fhnA:
undetectable		 3ozwA-3fhnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flu DIHYDRODIPICOLINATE
SYNTHASE

(Neisseria
meningitidis) 		PF00701
(DHDPS) 		4 ILE A 132
ALA A 152
LEU A 151
PRO A 178
 None
 0.73A 3ozwA-3fluA:
undetectable		 3ozwA-3fluA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 ILE A  29
ALA A  66
LEU A  65
PRO A 182
 None
 0.63A 3ozwA-3gbrA:
2.6		 3ozwA-3gbrA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Bos taurus) 		PF04869
(Uso1_p115_head) 		4 ILE A 584
GLN A 535
ALA A 542
LEU A 543
 None
 0.61A 3ozwA-3gq2A:
undetectable		 3ozwA-3gq2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
-C REDUCTASE COMPLEX
CORE PROTEIN 2

(Gallus gallus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 TYR B  99
GLN B 376
ALA B 375
LEU B 379
 None
 0.84A 3ozwA-3h1lB:
undetectable		 3ozwA-3h1lB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9w DIGUANYLATE CYCLASE
WITH PAS/PAC SENSOR

(Marinobacter
hydrocarbonoclasticus) 		PF08447
(PAS_3) 		4 ILE A  25
GLN A  42
ALA A  45
LEU A  46
 None
 0.73A 3ozwA-3h9wA:
undetectable		 3ozwA-3h9wA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Streptococcus
pneumoniae) 		PF01380
(SIS) 		4 ILE A  21
GLN A 351
ALA A 354
LEU A 355
 None
 0.74A 3ozwA-3i0zA:
4.7		 3ozwA-3i0zA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3w PHOSPHOGLUCOSAMINE
MUTASE

(Francisella
tularensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A  98
ALA A  60
LEU A  61
LEU A 112
 None
 0.85A 3ozwA-3i3wA:
undetectable		 3ozwA-3i3wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 2

(Thermus
thermophilus) 		PF01257
(2Fe-2S_thioredx) 		4 ALA 2 152
LEU 2 154
LEU 2  80
PRO 2 169
 None
 0.83A 3ozwA-3i9v2:
undetectable		 3ozwA-3i9v2:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwa FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Desulfovibrio
vulgaris) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLN A 150
ALA A 252
LEU A 251
LEU A 227
 None
 0.88A 3ozwA-3iwaA:
3.0		 3ozwA-3iwaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju1 ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Shewanella
oneidensis) 		PF16113
(ECH_2) 		4 ILE A 153
ALA A 201
LEU A 200
LEU A 183
 None
 0.83A 3ozwA-3ju1A:
2.2		 3ozwA-3ju1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8a PUTATIVE
AMINOTRANSFERASE,
PROBABLE
BETA-CYSTATHIONASE

(Streptococcus
mutans) 		PF00155
(Aminotran_1_2) 		4 ILE A 312
ALA A 363
LEU A 325
LEU A 378
 None
 0.83A 3ozwA-3l8aA:
2.3		 3ozwA-3l8aA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m62 UBIQUITIN
CONJUGATION FACTOR
E4

(Saccharomyces
cerevisiae) 		PF04564
(U-box)
PF10408
(Ufd2P_core) 		4 ILE A 418
GLN A 438
ALA A 445
LEU A 446
 None
 0.86A 3ozwA-3m62A:
undetectable		 3ozwA-3m62A:
17.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator) 		no annotation 4 ALA B  56
LEU B  57
LEU B 102
PRO B 398
 ECN  B 411 (-3.5A)
ECN  B 411 (-4.1A)
ECN  B 411 (-3.2A)
HEM  B 404 (-4.4A)
 0.73A 3ozwA-3ozvB:
62.3		 3ozwA-3ozvB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator) 		no annotation 6 ILE B  25
TYR B  29
GLN B  50
GLN B  53
LEU B  57
LEU B 102
 ECN  B 411 (-4.5A)
None
FAD  B 405 (-3.1A)
HEM  B 404 (-3.9A)
ECN  B 411 (-4.1A)
ECN  B 411 (-3.2A)
 0.65A 3ozwA-3ozvB:
62.3		 3ozwA-3ozvB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator) 		no annotation 6 ILE B  25
TYR B  29
GLN B  53
ALA B  56
LEU B  57
LEU B 102
 ECN  B 411 (-4.5A)
None
HEM  B 404 (-3.9A)
ECN  B 411 (-3.5A)
ECN  B 411 (-4.1A)
ECN  B 411 (-3.2A)
 0.49A 3ozwA-3ozvB:
62.3		 3ozwA-3ozvB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qi6 CYSTATHIONINE
GAMMA-SYNTHASE METB
(CGS)

(Mycobacterium
ulcerans) 		PF01053
(Cys_Met_Meta_PP) 		4 ILE A 282
ALA A 273
LEU A 276
LEU A 324
 None
 0.88A 3ozwA-3qi6A:
undetectable		 3ozwA-3qi6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tcm ALANINE
AMINOTRANSFERASE 2

(Hordeum vulgare) 		PF00155
(Aminotran_1_2) 		4 ILE A  48
TYR A  50
GLN A  33
LEU A  32
 None
 0.80A 3ozwA-3tcmA:
2.3		 3ozwA-3tcmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tov GLYCOSYL TRANSFERASE
FAMILY 9

(Veillonella
parvula) 		PF01075
(Glyco_transf_9) 		4 ILE A 189
GLN A 230
ALA A 204
LEU A 283
 None
 0.74A 3ozwA-3tovA:
4.7		 3ozwA-3tovA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usw FLAGELLAR MOTOR
SWITCH PROTEIN

(Helicobacter
pylori) 		PF01706
(FliG_C)
PF14841
(FliG_M) 		4 ILE A 125
GLN A 129
LEU A 130
LEU A 191
 None
 0.81A 3ozwA-3uswA:
undetectable		 3ozwA-3uswA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vex O-CARBAMOYLTRANSFERA
SE TOBZ

(Streptoalloteichus
tenebrarius) 		PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C) 		4 TYR A 171
GLN A 282
ALA A 193
LEU A 180
 CA0  A 602 (-3.4A)
None
None
None
 0.85A 3ozwA-3vexA:
undetectable		 3ozwA-3vexA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		4 ILE A 392
GLN A  46
ALA A  49
LEU A  50
 None
 0.54A 3ozwA-3zxsA:
4.5		 3ozwA-3zxsA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT

(Carboxydothermus
hydrogenoformans) 		PF03599
(CdhD)
PF04060
(FeS) 		4 ILE A   8
GLN A  31
LEU A   3
LEU A  52
 None
 0.74A 3ozwA-4c1nA:
undetectable		 3ozwA-4c1nA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dgj ENTEROPEPTIDASE
CATALYTIC LIGHT
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 ILE A 111
GLN A 194
ALA A 202
LEU A 201
 None
 0.88A 3ozwA-4dgjA:
undetectable		 3ozwA-4dgjA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evi CONIFERYL ALCOHOL
9-O-METHYLTRANSFERAS
E

(Linum
nodiflorum) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 ILE A  41
GLN A  82
ALA A 101
LEU A 100
 None
 0.82A 3ozwA-4eviA:
2.6		 3ozwA-4eviA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxz SUPPRESSION OF
COPPER SENSITIVITY
PROTEIN

(Salmonella
enterica) 		PF01323
(DSBA) 		4 GLN A  98
GLN A  99
ALA A 102
LEU A 103
 None
 0.70A 3ozwA-4gxzA:
undetectable		 3ozwA-4gxzA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3w HYPOTHETICAL PROTEIN

(Parabacteroides
distasonis) 		PF15414
(DUF4621) 		4 ILE A  80
ALA A 211
LEU A 212
LEU A 197
 MLY  A  81 ( 3.8A)
MLY  A 128 ( 3.9A)
None
None
 0.77A 3ozwA-4h3wA:
undetectable		 3ozwA-4h3wA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iil MEMBRANE LIPOPROTEIN
TPN38(B)

(Treponema
pallidum) 		PF02608
(Bmp) 		4 ILE A  78
GLN A  73
ALA A  67
LEU A  66
 None
 0.86A 3ozwA-4iilA:
4.0		 3ozwA-4iilA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irx SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN

(Caulobacter
vibrioides) 		PF13407
(Peripla_BP_4) 		4 ILE A 195
ALA A 187
LEU A 186
LEU A 228
 None
 0.78A 3ozwA-4irxA:
3.0		 3ozwA-4irxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ita SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Synechococcus
sp. PCC 7002) 		PF00171
(Aldedh) 		4 ILE A 123
GLN A  33
ALA A  30
LEU A  29
 None
 0.80A 3ozwA-4itaA:
4.7		 3ozwA-4itaA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k35 GLYCOSIDE HYDROLASE
FAMILY 81
ENDO-BETA-1,3-GLUCAN
ASE

(Rhizomucor
miehei) 		PF03639
(Glyco_hydro_81) 		4 ILE A 372
GLN A 417
ALA A 399
LEU A 398
 None
 0.80A 3ozwA-4k35A:
undetectable		 3ozwA-4k35A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ly4 PEPTIDOGLYCAN
DEACETYLASE

(Helicobacter
pylori) 		PF01522
(Polysacc_deac_1) 		4 ILE A 192
TYR A 145
ALA A   8
PRO A  56
 None
 0.81A 3ozwA-4ly4A:
undetectable		 3ozwA-4ly4A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mlc EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfitobacterium
hafniense) 		PF13458
(Peripla_BP_6) 		4 ILE A  90
GLN A  64
ALA A  61
LEU A  60
 None
 0.83A 3ozwA-4mlcA:
6.0		 3ozwA-4mlcA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnz PROBABLE ZINC
PROTEASE

(Pseudomonas
aeruginosa) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 ILE A 349
GLN A 403
ALA A 267
LEU A 270
 None
 0.87A 3ozwA-4nnzA:
undetectable		 3ozwA-4nnzA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nwz FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Caldalkalibacillus
thermarum) 		PF07992
(Pyr_redox_2) 		4 ILE A   6
GLN A  23
ALA A 327
LEU A 330
 None
 0.78A 3ozwA-4nwzA:
3.6		 3ozwA-4nwzA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 ILE A 659
ALA A 584
LEU A 583
LEU A 606
 None
 0.62A 3ozwA-4q2cA:
2.3		 3ozwA-4q2cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3z ARGININE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 ILE B 404
TYR B 406
GLN B 424
LEU B 235
 None
 0.74A 3ozwA-4r3zB:
4.8		 3ozwA-4r3zB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcd PTERIDINE REDUCTASE

(Trypanosoma
brucei) 		PF13561
(adh_short_C2) 		4 ILE A  32
GLN A  60
ALA A  40
LEU A  44
 None
 0.73A 3ozwA-4wcdA:
5.4		 3ozwA-4wcdA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8k RNA POLYMERASE SIGMA
FACTOR SIGA

(Mycobacterium
tuberculosis) 		PF00140
(Sigma70_r1_2)
PF04542
(Sigma70_r2) 		4 ILE A 351
GLN A 322
ALA A 307
LEU A 306
 None
 0.79A 3ozwA-4x8kA:
undetectable		 3ozwA-4x8kA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yry DIHYDROPYRIMIDINE
DEHYDROGENASE
SUBUNIT A

(Thermotoga
maritima) 		PF07992
(Pyr_redox_2)
PF14691
(Fer4_20) 		4 ILE B  61
GLN B  37
ALA B 112
LEU B  76
 None
 0.67A 3ozwA-4yryB:
4.4		 3ozwA-4yryB:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zad FDC1

(Candida
dubliniensis) 		PF01977
(UbiD) 		4 ILE A 102
GLN A  96
LEU A  91
LEU A 337
 None
 0.74A 3ozwA-4zadA:
undetectable		 3ozwA-4zadA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zaj ARGININE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 ILE A 332
TYR A 334
GLN A 352
LEU A 163
 None
 0.86A 3ozwA-4zajA:
4.7		 3ozwA-4zajA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afu DYNACTIN

(Sus scrofa) 		PF00022
(Actin) 		4 ILE J 384
ALA J 121
LEU J 120
LEU J 109
 None
 0.83A 3ozwA-5afuJ:
undetectable		 3ozwA-5afuJ:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3o THYMINE DIOXYGENASE

(Neurospora
crassa) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 ILE A  53
GLN A 155
ALA A 158
LEU A 159
 EDO  A 403 (-4.7A)
None
None
None
 0.86A 3ozwA-5c3oA:
undetectable		 3ozwA-5c3oA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 ILE A 260
GLN A  10
ALA A  13
LEU A  14
 None
 0.64A 3ozwA-5e2eA:
undetectable		 3ozwA-5e2eA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqx DESMOGLEIN-3

(Homo sapiens) 		PF00028
(Cadherin) 		4 ILE A  34
TYR A  36
GLN A  29
ALA A  30
 None
 0.82A 3ozwA-5eqxA:
undetectable		 3ozwA-5eqxA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC

(Zea mays) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ALA A 218
LEU A 221
LEU A 273
PRO A 128
 None
 0.87A 3ozwA-5h8yA:
undetectable		 3ozwA-5h8yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1h EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Homo sapiens) 		PF00076
(RRM_1)
PF08662
(eIF2A) 		4 ILE B 312
TYR B 251
GLN B 272
LEU B 313
 None
 0.84A 3ozwA-5k1hB:
undetectable		 3ozwA-5k1hB:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kko UNCHARACTERISED
PROTEIN

(Vibrio cholerae) 		no annotation 4 ILE A  17
GLN A  27
ALA A  34
PRO A  48
 None
 0.75A 3ozwA-5kkoA:
undetectable		 3ozwA-5kkoA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4w CULLIN-2

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 ILE A 425
GLN A 432
ALA A 392
LEU A 391
 None
 0.78A 3ozwA-5n4wA:
2.1		 3ozwA-5n4wA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 4 ILE B 351
GLN B 310
ALA B 313
LEU B 314
 None
 0.62A 3ozwA-5vqiB:
undetectable		 3ozwA-5vqiB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vx6 UNCHARACTERIZED
PROTEIN YPFA

(Bacillus
subtilis) 		no annotation 4 ILE A 164
ALA A 198
LEU A 199
LEU A 109
 None
 0.81A 3ozwA-5vx6A:
2.3		 3ozwA-5vx6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg VACUOLAR PROTEIN 8

(Saccharomyces
cerevisiae) 		PF00514
(Arm) 		4 ILE A 101
GLN A  64
ALA A  67
LEU A  94
 None
 0.84A 3ozwA-5xjgA:
undetectable		 3ozwA-5xjgA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 ILE A 633
ALA A 450
LEU A 451
LEU A 644
 None
 0.87A 3ozwA-5y7oA:
2.1		 3ozwA-5y7oA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE

(Pseudomonas
aeruginosa) 		no annotation 4 ILE A  31
ALA A 389
LEU A  51
PRO A 380
 None
 0.83A 3ozwA-5ykdA:
undetectable		 3ozwA-5ykdA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az0 MITOCHONDRIAL INNER
MEMBRANE I-AAA
PROTEASE
SUPERCOMPLEX SUBUNIT
YME1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 546
TYR A 550
LEU A 688
LEU A 557
 None
 0.70A 3ozwA-6az0A:
undetectable		 3ozwA-6az0A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN

(Shewanella
frigidimarina) 		no annotation 4 ILE A  22
TYR A  45
GLN A  20
LEU A  60
 None
 0.74A 3ozwA-6bg8A:
undetectable		 3ozwA-6bg8A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B

(Flavobacterium
johnsoniae) 		no annotation 4 ILE B 352
GLN B 304
ALA B 307
LEU B 308
 None
 0.52A 3ozwA-6btmB:
2.9		 3ozwA-6btmB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evg MULTI-COPPER OXIDASE
CUEO

(Ochrobactrum) 		no annotation 4 ILE A 121
GLN A 123
LEU A  70
LEU A  78
 None
 0.83A 3ozwA-6evgA:
undetectable		 3ozwA-6evgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE B 541
ALA B 346
LEU B 347
LEU B 549
 None
 0.87A 3ozwA-6f42B:
undetectable		 3ozwA-6f42B:
11.41