SIMILAR PATTERNS OF AMINO ACIDS FOR 3OZK_B_T44B128

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE

(Bacillus
subtilis) 		PF01648
(ACPS) 		4 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.73A 3ozkB-1f80A:
undetectable		 3ozkB-1f80A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1few SECOND
MITOCHONDRIA-DERIVED
ACTIVATOR OF
CASPASES

(Homo sapiens) 		PF09057
(Smac_DIABLO) 		4 ALA A 112
SER A  31
THR A  27
VAL A  23
 None
 1.00A 3ozkB-1fewA:
undetectable		 3ozkB-1fewA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fi4 MEVALONATE
5-DIPHOSPHATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00288
(GHMP_kinases_N) 		4 ALA A  51
SER A   7
THR A   5
VAL A   3
 None
 0.49A 3ozkB-1fi4A:
0.0		 3ozkB-1fi4A:
16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.59A 3ozkB-1gkeA:
21.4		 3ozkB-1gkeA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq8 PECTINESTERASE

(Daucus carota) 		PF01095
(Pectinesterase) 		4 LEU A 261
SER A 231
THR A 233
VAL A 235
 None
 1.03A 3ozkB-1gq8A:
undetectable		 3ozkB-1gq8A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmy BILE-SALT-ACTIVATED
LIPASE

(Homo sapiens) 		PF00135
(COesterase) 		4 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 1.00A 3ozkB-1jmyA:
undetectable		 3ozkB-1jmyA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE

(Caenorhabditis
elegans) 		PF00293
(NUDIX) 		4 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.78A 3ozkB-1kt9A:
0.2		 3ozkB-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.74A 3ozkB-1pgsA:
undetectable		 3ozkB-1pgsA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz8 FAB 17B HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ALA B  93
SER B  33
THR B  35
VAL B  37
 None
 0.39A 3ozkB-1rz8B:
0.0		 3ozkB-1rz8B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE BETA
SUBUNIT

(Thauera
aromatica) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 LEU B 252
ALA B 240
LEU B 242
SER B 219
 None
 0.82A 3ozkB-1sb3B:
0.0		 3ozkB-1sb3B:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.86A 3ozkB-1skyB:
undetectable		 3ozkB-1skyB:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.34A 3ozkB-1sn2A:
20.9		 3ozkB-1sn2A:
53.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4n RIBONUCLEASE III

(Saccharomyces
cerevisiae) 		PF00035
(dsrm) 		4 LYS A 443
ALA A 446
LEU A 377
SER A 376
 None
 1.02A 3ozkB-1t4nA:
undetectable		 3ozkB-1t4nA:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.45A 3ozkB-1tfpA:
19.7		 3ozkB-1tfpA:
73.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.78A 3ozkB-1wcdJ:
undetectable		 3ozkB-1wcdJ:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg2 PECTINESTERASE 1

(Solanum
lycopersicum) 		PF01095
(Pectinesterase) 		4 LEU A 257
SER A 227
THR A 229
VAL A 231
 None
 1.02A 3ozkB-1xg2A:
undetectable		 3ozkB-1xg2A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ysr SENSOR-TYPE
HISTIDINE KINASE
PRRB

(Mycobacterium
tuberculosis) 		PF02518
(HATPase_c) 		4 LEU A 328
ALA A 367
LEU A 365
VAL A 374
 None
 0.99A 3ozkB-1ysrA:
undetectable		 3ozkB-1ysrA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anp LEUCYL
AMINOPEPTIDASE

(Vibrio
proteolyticus) 		PF04389
(Peptidase_M28) 		4 ALA A 144
SER A 142
THR A  81
VAL A  79
 None
 0.96A 3ozkB-2anpA:
undetectable		 3ozkB-2anpA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bhm TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 ALA A 181
SER A 162
THR A 164
VAL A 166
 None
 0.69A 3ozkB-2bhmA:
undetectable		 3ozkB-2bhmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2i RV0130

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas) 		4 LEU A  91
ALA A 143
THR A 129
VAL A 131
 None
 0.62A 3ozkB-2c2iA:
undetectable		 3ozkB-2c2iA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eh0 KINESIN-LIKE PROTEIN
KIF1B

(Homo sapiens) 		PF00498
(FHA)
PF16183
(Kinesin_assoc) 		4 LEU A  95
SER A  62
THR A  33
VAL A  35
 None
 1.01A 3ozkB-2eh0A:
undetectable		 3ozkB-2eh0A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk4 CONSERVED
HYPOTHETICAL PROTEIN

(Streptococcus
pneumoniae) 		PF04127
(DFP) 		4 LYS A 158
LEU A 160
ALA A 186
VAL A 202
 None
 0.73A 3ozkB-2gk4A:
undetectable		 3ozkB-2gk4A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		4 LEU A  36
ALA A 409
THR A 238
VAL A 235
 None
 1.01A 3ozkB-2iyaA:
undetectable		 3ozkB-2iyaA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5v DNA REPLICATION AND
REPAIR PROTEIN RECF

(Deinococcus
radiodurans) 		PF02463
(SMC_N) 		4 LEU A   6
LEU A  76
SER A  83
VAL A  87
 None
 1.03A 3ozkB-2o5vA:
undetectable		 3ozkB-2o5vA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 LEU A 237
ALA A 456
SER A 466
THR A 460
 None
 1.03A 3ozkB-2pq6A:
undetectable		 3ozkB-2pq6A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjq ADAMTS-5

(Homo sapiens) 		PF01421
(Reprolysin) 		4 LEU A 321
SER A 278
THR A 366
VAL A 396
 None
 1.01A 3ozkB-2rjqA:
undetectable		 3ozkB-2rjqA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9u MSPA

(Mycolicibacterium
smegmatis) 		PF09203
(MspA) 		4 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.66A 3ozkB-2v9uA:
3.4		 3ozkB-2v9uA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6d DYNAMIN FAMILY
PROTEIN

(Nostoc
punctiforme) 		PF00350
(Dynamin_N) 		4 LEU A  49
ALA A  38
LEU A  51
THR A  34
 None
 0.86A 3ozkB-2w6dA:
undetectable		 3ozkB-2w6dA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wua ACETOACETYL COA
THIOLASE

(Helianthus
annuus) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LEU A  77
LEU A 163
SER A 102
THR A 131
 None
 1.03A 3ozkB-2wuaA:
undetectable		 3ozkB-2wuaA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoc PULLULANASE

(Klebsiella
oxytoca) 		PF02922
(CBM_48)
PF03714
(PUD)
PF11852
(DUF3372) 		4 ALA A 251
SER A 262
THR A 264
VAL A 266
 None
 0.91A 3ozkB-2yocA:
undetectable		 3ozkB-2yocA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ALA A 149
SER A 226
THR A 228
VAL A 230
 None
 0.87A 3ozkB-2yv3A:
undetectable		 3ozkB-2yv3A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxp PUTATIVE
LIPASE/ESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.76A 3ozkB-3bxpA:
undetectable		 3ozkB-3bxpA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT
ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh)
PF03063
(Prismane) 		4 ALA G 127
LEU G 125
THR A  70
VAL A  68
 ACY  A 821 (-3.6A)
PEG  G 173 ( 4.0A)
None
ACY  A 821 ( 4.3A)
 0.64A 3ozkB-3cf4G:
undetectable		 3ozkB-3cf4G:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Rhodospirillum
rubrum) 		PF00440
(TetR_N) 		4 LEU A 174
ALA A 106
LEU A 102
VAL A  68
 None
 0.99A 3ozkB-3cwrA:
undetectable		 3ozkB-3cwrA:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		5 LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 IFA  A3000 ( 4.7A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
IFA  A3000 ( 4.9A)
None
 0.47A 3ozkB-3fc8A:
23.4		 3ozkB-3fc8A:
99.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
None
 0.82A 3ozkB-3fc8A:
23.4		 3ozkB-3fc8A:
99.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaf 7-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Brucella
abortus) 		PF13561
(adh_short_C2) 		4 ALA A 188
SER A 247
THR A 245
VAL A 243
 None
 0.92A 3ozkB-3gafA:
undetectable		 3ozkB-3gafA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnn NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Burkholderia
pseudomallei) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 LEU A 118
LEU A 121
SER A 125
THR A 286
 None
 1.03A 3ozkB-3gnnA:
undetectable		 3ozkB-3gnnA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i44 ALDEHYDE
DEHYDROGENASE

(Bartonella
henselae) 		PF00171
(Aldedh) 		4 LEU A 173
LEU A 146
SER A 224
THR A 226
 None
 0.81A 3ozkB-3i44A:
undetectable		 3ozkB-3i44A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwk AMINOALDEHYDE
DEHYDROGENASE

(Pisum sativum) 		PF00171
(Aldedh) 		4 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
 0.91A 3ozkB-3iwkA:
undetectable		 3ozkB-3iwkA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe MHC CLASS II H2-IAG7
BETA CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.04A 3ozkB-3mbeB:
undetectable		 3ozkB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prx COBRA VENOM FACTOR

(Naja kaouthia) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.79A 3ozkB-3prxB:
2.6		 3ozkB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4g NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Vibrio cholerae) 		PF02540
(NAD_synthase) 		4 LYS A 203
ALA A 202
THR A  52
VAL A  48
 None
 0.96A 3ozkB-3q4gA:
undetectable		 3ozkB-3q4gA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qac 11S GLOBULIN SEED
STORAGE PROTEIN

(Amaranthus
hypochondriacus) 		PF00190
(Cupin_1) 		4 LEU A 318
ALA A 325
LEU A 323
VAL A 398
 None
 1.04A 3ozkB-3qacA:
undetectable		 3ozkB-3qacA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE

(Coccidioides
immitis) 		PF02502
(LacAB_rpiB) 		4 ALA A  12
SER A  38
THR A  40
VAL A  42
 None
 0.80A 3ozkB-3qd5A:
undetectable		 3ozkB-3qd5A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmg OCTAPRENYL-DIPHOSPHA
TE SYNTHASE

(Bacteroides
thetaiotaomicron) 		PF00348
(polyprenyl_synt) 		4 LEU A  52
ALA A 183
THR A  67
VAL A 187
 None
 0.93A 3ozkB-3rmgA:
undetectable		 3ozkB-3rmgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 LEU A 353
LEU A 350
SER A 347
VAL A1039
 None
 0.96A 3ozkB-3s51A:
undetectable		 3ozkB-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		4 LEU A 264
ALA A 260
LEU A 266
VAL A 248
 None
 0.79A 3ozkB-3si9A:
undetectable		 3ozkB-3si9A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6s CERJ

(Streptomyces
tendae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.89A 3ozkB-3t6sA:
undetectable		 3ozkB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 LEU A 169
LEU A 142
SER A 220
THR A 222
 None
 0.73A 3ozkB-3ty7A:
undetectable		 3ozkB-3ty7A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akz TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 ALA A 181
SER A 162
THR A 164
VAL A 166
 None
 0.74A 3ozkB-4akzA:
undetectable		 3ozkB-4akzA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7l FILAMIN-B

(Homo sapiens) 		PF00307
(CH)
PF00630
(Filamin) 		4 LYS A 255
ALA A 257
THR A 281
VAL A 279
 None
 0.87A 3ozkB-4b7lA:
undetectable		 3ozkB-4b7lA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkm PYRIDOXAL PHOSPHATE
PHOSPHATASE,
PHOSPHOGLYCOLATE
PHOSPHATASE,
PYRIDOXAL PHOSPHATE
PHOSPHATASE

(Mus musculus) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 ALA A  92
LEU A  90
SER A  87
VAL A 156
 None
 0.91A 3ozkB-4bkmA:
undetectable		 3ozkB-4bkmA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmg PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493

(Thermus
thermophilus) 		PF02475
(Met_10) 		4 LEU A 259
ALA A 255
LEU A 261
VAL A 225
 None
 1.05A 3ozkB-4dmgA:
undetectable		 3ozkB-4dmgA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft2 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Zea mays) 		PF00145
(DNA_methylase)
PF00385
(Chromo)
PF01426
(BAH) 		4 LEU A 608
ALA A 587
LEU A 589
SER A 303
 None
 1.04A 3ozkB-4ft2A:
undetectable		 3ozkB-4ft2A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 11

(Thermus
thermophilus) 		PF00420
(Oxidored_q2) 		4 LEU K   5
ALA K   8
LEU K   4
SER K  41
 None
 1.02A 3ozkB-4heaK:
undetectable		 3ozkB-4heaK:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjh PHOSPHOMANNOMUTASE

(Brucella
melitensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 194
LEU A 197
SER A 171
VAL A 359
 None
None
EDO  A 546 ( 4.3A)
None
 0.86A 3ozkB-4hjhA:
undetectable		 3ozkB-4hjhA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hnr CHEMOTAXIS PROTEIN
CHEY

(Vibrio cholerae) 		PF00072
(Response_reg) 		4 LEU A  81
ALA A   6
THR A  30
VAL A  28
 None
 0.72A 3ozkB-4hnrA:
undetectable		 3ozkB-4hnrA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE

(Solanum
lycopersicum) 		PF00171
(Aldedh) 		4 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.87A 3ozkB-4i8qA:
undetectable		 3ozkB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4il7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Sulfolobus
turreted
icosahedral
virus 1) 		no annotation 4 ALA A 215
LEU A 217
SER A 165
THR A 167
 None
 0.59A 3ozkB-4il7A:
undetectable		 3ozkB-4il7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhp X-LINKED RETINITIS
PIGMENTOSA GTPASE
REGULATOR

(Homo sapiens) 		PF00415
(RCC1) 		4 LEU C 224
LEU C 222
THR C 255
VAL C 257
 None
 0.90A 3ozkB-4jhpC:
undetectable		 3ozkB-4jhpC:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ALA A 466
LEU A 468
THR A 471
VAL A 474
 None
 1.06A 3ozkB-4k9qA:
undetectable		 3ozkB-4k9qA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4keg MALTOSE-BINDING
PERIPLASMIC/PALATE
LUNG AND NASAL
EPITHELIUM CLONE
FUSION PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF01273
(LBP_BPI_CETP)
PF13416
(SBP_bac_8) 		4 LEU A1135
LEU A1157
SER A1186
VAL A1131
 None
 0.92A 3ozkB-4kegA:
undetectable		 3ozkB-4kegA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN

(Yersinia pestis) 		PF03548
(LolA) 		4 ALA A 149
SER A 160
THR A 162
VAL A 164
 None
 0.54A 3ozkB-4ki3A:
undetectable		 3ozkB-4ki3A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpn NUCLEOSIDE
N-RIBOHYDROLASE 1

(Physcomitrella
patens) 		PF01156
(IU_nuc_hydro) 		4 LEU A 326
LEU A 256
THR A 210
VAL A 205
 None
 1.02A 3ozkB-4kpnA:
undetectable		 3ozkB-4kpnA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 LEU A  86
ALA A  41
THR A  11
VAL A   9
 None
 0.72A 3ozkB-4l1yA:
undetectable		 3ozkB-4l1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lj2 CHORISMATE SYNTHASE

(Acinetobacter
baumannii) 		PF01264
(Chorismate_synt) 		4 ALA A  25
LEU A  23
THR A  14
VAL A  12
 None
 0.59A 3ozkB-4lj2A:
undetectable		 3ozkB-4lj2A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mio INOSITOL
2-DEHYDROGENASE/D-CH
IRO-INOSITOL
3-DEHYDROGENASE

(Lactobacillus
casei) 		PF01408
(GFO_IDH_MocA) 		4 LEU A 213
LEU A 227
SER A 154
VAL A 150
 None
None
GOL  A 402 (-2.8A)
None
 0.92A 3ozkB-4mioA:
undetectable		 3ozkB-4mioA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5i CHEMOKINE BINDING
PROTEIN

(Orf virus) 		PF02250
(Orthopox_35kD) 		4 LEU A 208
ALA A 145
SER A  82
VAL A  86
 None
None
NAG  A 301 ( 4.9A)
None
 0.84A 3ozkB-4p5iA:
undetectable		 3ozkB-4p5iA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pka PATATIN-17

(Solanum
cardiophyllum) 		PF01734
(Patatin) 		4 ALA X  84
LEU X  81
THR X  83
VAL X 150
 None
MIS  X  77 ( 4.0A)
None
None
 1.00A 3ozkB-4pkaX:
undetectable		 3ozkB-4pkaX:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP2

(Enterovirus C) 		PF00073
(Rhv) 		4 ALA 2  31
SER 2 204
THR 2 206
VAL 2 208
 None
 0.89A 3ozkB-4q4y2:
undetectable		 3ozkB-4q4y2:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2f EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Pseudarthrobacter
chlorophenolicus) 		PF01547
(SBP_bac_1) 		4 ALA A 410
LEU A 408
SER A 405
VAL A 445
 None
 1.06A 3ozkB-4r2fA:
undetectable		 3ozkB-4r2fA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twe N-ACETYLATED-ALPHA-L
INKED ACIDIC
DIPEPTIDASE-LIKE
PROTEIN

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 ALA A 602
LEU A 600
THR A 692
VAL A 690
 None
 0.88A 3ozkB-4tweA:
undetectable		 3ozkB-4tweA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uir OLEATE HYDRATASE

(Elizabethkingia
meningoseptica) 		PF06100
(MCRA) 		4 LEU A 493
SER A 399
THR A 500
VAL A 502
 None
 0.92A 3ozkB-4uirA:
undetectable		 3ozkB-4uirA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa2 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MBP-PILA: C

(Acinetobacter
baumannii;
Escherichia
coli) 		PF00114
(Pilin)
PF13416
(SBP_bac_8) 		4 LYS A1094
ALA A1073
SER A1031
THR A1035
 None
 0.99A 3ozkB-4xa2A:
undetectable		 3ozkB-4xa2A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvx ACYL-[ACYL-CARRIER-P
ROTEIN]
DEHYDROGENASE MBTN

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LYS A 312
LEU A 362
ALA A 308
LEU A 365
 None
 1.00A 3ozkB-4xvxA:
undetectable		 3ozkB-4xvxA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE

(Actinobacillus
succinogenes) 		PF13407
(Peripla_BP_4) 		4 LEU A 232
ALA A 253
THR A 291
VAL A 289
 None
 0.70A 3ozkB-4zjpA:
undetectable		 3ozkB-4zjpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		4 LEU A 428
ALA A 376
THR A 369
VAL A 365
 None
 1.03A 3ozkB-5a5gA:
undetectable		 3ozkB-5a5gA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2o CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Francisella
tularensis) 		no annotation 4 LYS A1222
LEU A  43
THR A  17
VAL A  19
 None
 0.75A 3ozkB-5b2oA:
undetectable		 3ozkB-5b2oA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7s LON PROTEASE

(Meiothermus
taiwanensis) 		PF05362
(Lon_C) 		4 LEU A 769
ALA A 597
SER A 689
THR A 596
 None
 1.02A 3ozkB-5e7sA:
undetectable		 3ozkB-5e7sA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT

(Escherichia
coli) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 ALA C 449
SER C 503
THR C 463
VAL C 461
 None
 0.98A 3ozkB-5g5gC:
undetectable		 3ozkB-5g5gC:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos taurus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LYS H  13
LEU H  11
SER H  87
THR H  84
 None
 0.90A 3ozkB-5ihuH:
undetectable		 3ozkB-5ihuH:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ik2 ATP SYNTHASE SUBUNIT
ALPHA

(Caldalkalibacillus
thermarum) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ALA A 197
SER A 227
THR A 225
VAL A 223
 None
 0.93A 3ozkB-5ik2A:
undetectable		 3ozkB-5ik2A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvf SITE-DETERMINING
PROTEIN

(Pseudomonas
aeruginosa) 		PF10609
(ParA) 		4 ALA A  47
LEU A  49
THR A 128
VAL A 126
 None
 0.89A 3ozkB-5jvfA:
undetectable		 3ozkB-5jvfA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans) 		no annotation 4 LEU B 826
ALA B 822
LEU B 841
THR B 819
 None
 0.98A 3ozkB-5khnB:
undetectable		 3ozkB-5khnB:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2p ARYLESTERASE

(Sulfolobus
solfataricus) 		PF07859
(Abhydrolase_3) 		4 ALA A 243
SER A 273
THR A 271
VAL A 269
 None
 0.89A 3ozkB-5l2pA:
undetectable		 3ozkB-5l2pA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocp -

(-) 		no annotation 4 LEU A 218
ALA A 239
THR A 277
VAL A 275
 None
 0.97A 3ozkB-5ocpA:
undetectable		 3ozkB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujv ABSCISIC ACID
RECEPTOR

(Escherichia
coli) 		no annotation 4 ALA A 122
SER A 144
THR A 142
VAL A 140
 None
 0.80A 3ozkB-5ujvA:
undetectable		 3ozkB-5ujvA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uvn PARAQUAT-INDUCIBLE
PROTEIN B

(Escherichia
coli) 		PF02470
(MlaD) 		4 LEU A 289
LEU A 338
SER A 316
VAL A 296
 None
 1.02A 3ozkB-5uvnA:
undetectable		 3ozkB-5uvnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5va8 SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Paraburkholderia
phymatum) 		PF13561
(adh_short_C2) 		4 LEU A  85
SER A   9
THR A  35
VAL A  62
 None
 0.94A 3ozkB-5va8A:
undetectable		 3ozkB-5va8A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzj EXOSOME COMPLEX
EXONUCLEASE RRP6

(Saccharomyces
cerevisiae) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		4 LYS J 230
LEU J 226
LEU J 277
THR J 282
 None
 1.01A 3ozkB-5vzjJ:
undetectable		 3ozkB-5vzjJ:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w42 -

(-) 		no annotation 4 ALA H  93
SER H  33
THR H  35
VAL H  37
 None
 0.32A 3ozkB-5w42H:
undetectable		 3ozkB-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7p OXAC

(Penicillium
oxalicum) 		no annotation 4 ALA A 303
SER A 235
THR A 238
VAL A 240
 None
 0.92A 3ozkB-5w7pA:
undetectable		 3ozkB-5w7pA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w81 CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Danio rerio) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 LEU A 601
ALA A 572
LEU A 570
SER A 490
 None
 0.93A 3ozkB-5w81A:
undetectable		 3ozkB-5w81A:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 LEU A 333
ALA A 329
SER A 359
THR A 327
 None
 0.92A 3ozkB-5y3jA:
undetectable		 3ozkB-5y3jA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z96 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 4

(Mus musculus) 		no annotation 4 ALA A 210
LEU A 208
SER A 205
VAL A 718
 None
 0.71A 3ozkB-5z96A:
undetectable		 3ozkB-5z96A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9a CHORISMATE SYNTHASE

(Pseudomonas
aeruginosa) 		no annotation 4 ALA A  25
LEU A  23
THR A  14
VAL A  12
 None
 0.63A 3ozkB-5z9aA:
undetectable		 3ozkB-5z9aA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE

(Homo sapiens) 		no annotation 4 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.04A 3ozkB-6b92A:
undetectable		 3ozkB-6b92A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5u ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1

(Zaire
ebolavirus) 		no annotation 4 LYS A 276
SER A 307
THR A 309
VAL A 311
 None
 0.78A 3ozkB-6f5uA:
undetectable		 3ozkB-6f5uA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1k TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY C
MEMBER 4A

(Danio rerio) 		no annotation 4 ALA A 210
LEU A 208
SER A 205
VAL A 717
 None
 0.64A 3ozkB-6g1kA:
undetectable		 3ozkB-6g1kA:
22.58