SIMILAR PATTERNS OF AMINO ACIDS FOR 3OXV_A_478A200

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 GLU A 624
TRP A 375
PRO A 615
ARG A 623
 None
 1.34A 3oxvA-1bhgA:
0.0		 3oxvA-1bhgA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 GLU A 403
PRO A 360
ARG A 361
GLY A 568
 None
 1.18A 3oxvA-1c30A:
undetectable		 3oxvA-1c30A:
7.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.79A 3oxvA-1hvcA:
14.0		 3oxvA-1hvcA:
47.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmz AMINE DEHYDROGENASE

(Pseudomonas
putida) 		no annotation 4 TRP B 187
PRO B 195
ARG B 189
GLY B 191
 None
 1.44A 3oxvA-1jmzB:
0.0		 3oxvA-1jmzB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 GLU A 651
PRO A 513
ARG A 649
GLY A 650
 None
 1.39A 3oxvA-1kcwA:
undetectable		 3oxvA-1kcwA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mb9 BETA-LACTAM
SYNTHETASE

(Streptomyces
clavuligerus) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		4 GLU A 341
TRP A 394
PRO A 385
GLY A 392
 None
 1.22A 3oxvA-1mb9A:
undetectable		 3oxvA-1mb9A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 GLU X  63
PRO X  75
ARG X  64
GLY X  65
 None
 1.45A 3oxvA-1mw9X:
undetectable		 3oxvA-1mw9X:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nr3 DNA-BINDING PROTEIN
TFX

(Methanothermobacter
thermautotrophicus) 		PF14601
(TFX_C) 		4 GLU A 115
PRO A  49
ARG A 112
GLY A 114
 None
 1.32A 3oxvA-1nr3A:
undetectable		 3oxvA-1nr3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhb HALOPEROXIDASE

(Corallina
officinalis) 		PF01569
(PAP2) 		4 GLU A  39
PRO A 407
ARG A 404
GLY A  55
 None
 1.44A 3oxvA-1qhbA:
undetectable		 3oxvA-1qhbA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhy IMIDAZOLE GLYCEROL
PHOSPHATE
DEHYDRATASE

(Cryptococcus
neoformans) 		PF00475
(IGPD) 		4 GLU A 164
PRO A 104
ARG A 162
GLY A 163
 None
 1.26A 3oxvA-1rhyA:
undetectable		 3oxvA-1rhyA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5x PHOSPHORIBOSYLANTHRA
NILATE ISOMERASE

(Thermus
thermophilus) 		PF00697
(PRAI) 		4 GLU A  47
PRO A  39
ARG A  43
GLY A  46
 None
 1.33A 3oxvA-1v5xA:
undetectable		 3oxvA-1v5xA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cja SERYL-TRNA
SYNTHETASE

(Methanosarcina
barkeri) 		no annotation 4 GLU A 316
TRP A 310
PRO A 444
GLY A 315
 None
 1.09A 3oxvA-2cjaA:
undetectable		 3oxvA-2cjaA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gm8 TENA HOMOLOG/THI-4
THIAMINASE

(Pyrobaculum
aerophilum) 		PF03070
(TENA_THI-4) 		4 TRP A  14
PRO A 133
ARG A   7
GLY A   4
 None
 1.41A 3oxvA-2gm8A:
undetectable		 3oxvA-2gm8A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hg6 HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF09634
(DUF2025) 		4 GLU A  67
PRO A  97
ARG A  66
GLY A  65
 None
 0.94A 3oxvA-2hg6A:
undetectable		 3oxvA-2hg6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oeh AT-RICH INTERACTIVE
DOMAIN-CONTAINING
PROTEIN 5B

(Homo sapiens) 		PF01388
(ARID) 		4 GLU A  95
PRO A  87
ARG A  90
GLY A  94
 None
 1.38A 3oxvA-2oehA:
undetectable		 3oxvA-2oehA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og9 MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Polaromonas sp.
JS666) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A 265
PRO A 290
ARG A 291
GLY A 264
 None
 1.25A 3oxvA-2og9A:
undetectable		 3oxvA-2og9A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 GLU A  33
PRO A  36
ARG A  34
GLY A  32
 None
 1.42A 3oxvA-2qheA:
undetectable		 3oxvA-2qheA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 GLU 1 321
PRO 1 137
ARG 1 133
GLY 1 320
 None
 1.37A 3oxvA-2r6r1:
undetectable		 3oxvA-2r6r1:
12.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rkf PROTEASE RETROPEPSIN

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.92A 3oxvA-2rkfA:
20.9		 3oxvA-2rkfA:
82.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynk WZI

(Escherichia
coli) 		PF14052
(Caps_assemb_Wzi) 		4 GLU A 301
TRP A  39
ARG A  43
GLY A  44
 None
 1.22A 3oxvA-2ynkA:
undetectable		 3oxvA-2ynkA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4d 26S PROTEASOME
REGULATORY SUBUNIT
RPN13

(Saccharomyces
cerevisiae) 		PF04683
(Proteasom_Rpn13) 		4 GLU A  54
TRP A 100
PRO A  28
GLY A  31
 None
 1.42A 3oxvA-2z4dA:
undetectable		 3oxvA-2z4dA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo4 METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Thermus
thermophilus) 		PF00753
(Lactamase_B) 		4 GLU A  95
PRO A 210
ARG A  98
GLY A 174
 None
 1.43A 3oxvA-2zo4A:
undetectable		 3oxvA-2zo4A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b7f GLYCOSYL HYDROLASE,
BNR REPEAT

(Cupriavidus
pinatubonensis) 		no annotation 4 GLU A 322
PRO A 289
ARG A 256
GLY A 321
 None
None
EDO  A 402 (-3.1A)
None
 1.47A 3oxvA-3b7fA:
undetectable		 3oxvA-3b7fA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 GLU B  25
PRO B  15
ARG B  14
GLY B  24
 None
 1.21A 3oxvA-3hhsB:
undetectable		 3oxvA-3hhsB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7u AP4A HYDROLASE

(Aquifex
aeolicus) 		PF00293
(NUDIX) 		4 GLU A  91
PRO A  94
ARG A  93
GLY A  90
 None
 1.27A 3oxvA-3i7uA:
undetectable		 3oxvA-3i7uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwc MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Kosmotoga
olearia) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A 251
TRP A 220
ARG A 252
GLY A 250
 None
 1.27A 3oxvA-3mwcA:
undetectable		 3oxvA-3mwcA:
16.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.40A 3oxvA-3mwsA:
19.9		 3oxvA-3mwsA:
75.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rht (GATASE1)-LIKE
PROTEIN

(Planctopirus
limnophila) 		PF07090
(GATase1_like) 		4 GLU A 195
PRO A 134
ARG A 200
GLY A 194
 None
 1.50A 3oxvA-3rhtA:
undetectable		 3oxvA-3rhtA:
15.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3t3c HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.53A 3oxvA-3t3cA:
18.7		 3oxvA-3t3cA:
75.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		4 GLU A 110
TRP A 529
ARG A 111
GLY A 107
 None
 1.30A 3oxvA-3ucqA:
undetectable		 3oxvA-3ucqA:
9.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3uhl PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.63A 3oxvA-3uhlA:
16.5		 3oxvA-3uhlA:
78.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00005
(ABC_tran) 		4 GLU A 634
PRO A 296
ARG A 685
GLY A 684
 None
 1.32A 3oxvA-3zqjA:
undetectable		 3oxvA-3zqjA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a01 PROTON
PYROPHOSPHATASE

(Vigna radiata) 		PF03030
(H_PPase) 		4 GLU A 620
PRO A 274
ARG A 272
GLY A 617
 None
 1.15A 3oxvA-4a01A:
undetectable		 3oxvA-4a01A:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbm CURM
SULFOTRANSFERASE

(Moorea
producens) 		PF13469
(Sulfotransfer_3) 		4 GLU A 148
PRO A  29
ARG A  27
GLY A 147
 None
 1.36A 3oxvA-4gbmA:
undetectable		 3oxvA-4gbmA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr5 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
lydicus) 		PF00501
(AMP-binding)
PF03621
(MbtH) 		4 GLU A 442
PRO A  60
ARG A 443
GLY A 441
 TLA  A 602 ( 4.3A)
None
TLA  A 602 (-4.3A)
None
 1.37A 3oxvA-4gr5A:
undetectable		 3oxvA-4gr5A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ita SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Synechococcus
sp. PCC 7002) 		PF00171
(Aldedh) 		4 TRP A 135
PRO A 421
ARG A 139
GLY A 426
 EDO  A 516 (-4.6A)
None
NDP  A 501 ( 2.7A)
EDO  A 515 (-4.0A)
 1.48A 3oxvA-4itaA:
undetectable		 3oxvA-4itaA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qx8 LYSINE-SPECIFIC
DEMETHYLASE 2A

(Mus musculus) 		PF02373
(JmjC)
no annotation 		4 GLU A 364
TRP B 516
PRO A 174
ARG A 175
 None
 1.31A 3oxvA-4qx8A:
undetectable		 3oxvA-4qx8A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4usr MONOOXYGENASE

(Pseudomonas
stutzeri) 		PF13738
(Pyr_redox_3) 		4 GLU A 144
TRP A 280
ARG A 143
GLY A 142
 None
 1.43A 3oxvA-4usrA:
undetectable		 3oxvA-4usrA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 GLU A 624
PRO A 539
ARG A 349
GLY A 350
 None
 1.41A 3oxvA-4xmvA:
undetectable		 3oxvA-4xmvA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4r WELO5

(Hapalosiphon
welwitschii) 		no annotation 4 GLU A 202
PRO A 269
ARG A 270
GLY A 200
 None
None
AKG  A 301 (-2.6A)
None
 1.46A 3oxvA-5j4rA:
undetectable		 3oxvA-5j4rA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n7q PUTATIVE CATHEPSIN D

(Ixodes ricinus) 		no annotation 4 GLU A  85
TRP A  43
PRO A  45
GLY A  86
 None
 1.12A 3oxvA-5n7qA:
6.3		 3oxvA-5n7qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o36 JAPANESE
ENCEPHALITIS VIRUS
NON-STRUCTURAL
PROTEIN 1'
(NS1'),JAPANESE
ENCEPHALITIS VIRUS
NON-STRUCTURAL
PROTEIN 1' (NS1')

(Japanese
encephalitis
virus) 		no annotation 4 GLU A 258
PRO A 320
ARG A 257
GLY A 259
 None
 1.16A 3oxvA-5o36A:
undetectable		 3oxvA-5o36A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy9 GLYCOPROTEIN G

(Indiana
vesiculovirus) 		no annotation 4 GLU A 327
PRO A 262
ARG A 329
GLY A 313
 None
None
MLZ  A  50 ( 4.0A)
None
 1.29A 3oxvA-5oy9A:
undetectable		 3oxvA-5oy9A:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5t2z PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 TRP A  42
PRO A  44
ARG A  57
GLY A  78
 None
 0.29A 3oxvA-5t2zA:
20.0		 3oxvA-5t2zA:
78.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvr DNA REPAIR AND
RECOMBINATION
PROTEIN RAD26

(Saccharomyces
cerevisiae) 		no annotation 4 GLU M 470
PRO M 477
ARG M 475
GLY M 471
 None
 1.39A 3oxvA-5vvrM:
undetectable		 3oxvA-5vvrM:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3w ARYLDIALKYLPHOSPHATA
SE

(Sulfolobus
solfataricus) 		no annotation 4 GLU A  30
PRO A  67
ARG A  74
GLY A  73
 None
KCX  A 137 ( 4.6A)
None
None
 1.14A 3oxvA-5w3wA:
undetectable		 3oxvA-5w3wA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wg6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,POLYCOMB
PROTEIN SUZ12
(E.C.2.1.1.43)
CHIMERA

(Homo sapiens) 		no annotation 4 TRP A 113
PRO A 115
ARG A 685
GLY A 643
 None
None
A9G  A9009 (-3.1A)
None
 1.40A 3oxvA-5wg6A:
undetectable		 3oxvA-5wg6A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 GLU C1930
PRO C1991
ARG C1987
GLY C1929
 None
 1.11A 3oxvA-5y3rC:
undetectable		 3oxvA-5y3rC:
2.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywp JEV E PROTEIN

(Japanese
encephalitis
virus) 		no annotation 4 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 1.12A 3oxvA-5ywpA:
undetectable		 3oxvA-5ywpA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emv TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE

(Thermococcus
kodakarensis) 		no annotation 4 GLU A 220
PRO A 183
ARG A 231
GLY A 219
 None
SAH  A 301 (-3.9A)
None
None
 1.43A 3oxvA-6emvA:
undetectable		 3oxvA-6emvA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f74 ALCOHOL OXIDASE

(Thermothelomyces
thermophila) 		no annotation 4 GLU A 585
PRO A 572
ARG A 568
GLY A 583
 None
None
GOL  A 606 (-4.1A)
GOL  A 606 (-3.9A)
 1.45A 3oxvA-6f74A:
undetectable		 3oxvA-6f74A:
15.00