SIMILAR PATTERNS OF AMINO ACIDS FOR 3OU7_D_SAMD300
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b9b | PROTEIN(TRIOSEPHOSPHATEISOMERASE) (Thermotogamaritima) |
PF00121(TIM) | 5 | ALA A 237GLY A 235TRP A 11SER A 214ASP A 218 | NoneSO4 A 301 (-3.3A)NoneSO4 A 301 (-3.7A)None | 1.17A | 3ou7D-1b9bA:undetectable | 3ou7D-1b9bA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bf2 | ISOAMYLASE (Pseudomonasamyloderamosa) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 5 | TYR A 35GLY A 38GLY A 158ASP A 119LEU A 118 | None | 1.25A | 3ou7D-1bf2A:undetectable | 3ou7D-1bf2A:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhe | POLYGALACTURONASE (Pectobacteriumcarotovorum) |
PF00295(Glyco_hydro_28) | 5 | LEU A 59ALA A 41GLY A 39GLY A 112SER A 111 | None | 1.22A | 3ou7D-1bheA:undetectable | 3ou7D-1bheA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cem | CELLULASE CELA(1,4-BETA-D-GLUCAN-GLUCANOHYDROLASE) (Ruminiclostridiumthermocellum) |
PF01270(Glyco_hydro_8) | 5 | LEU A 350TYR A 41TRP A 284GLY A 347ASP A 349 | None | 0.97A | 3ou7D-1cemA:undetectable | 3ou7D-1cemA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cjy | PROTEIN (CYTOSOLICPHOSPHOLIPASE A2) (Homo sapiens) |
PF00168(C2)PF01735(PLA2_B) | 5 | ALA A 396GLY A 394GLY A 551SER A 550LEU A 421 | None | 1.18A | 3ou7D-1cjyA:undetectable | 3ou7D-1cjyA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1db3 | GDP-MANNOSE4,6-DEHYDRATASE (Escherichiacoli) |
PF16363(GDP_Man_Dehyd) | 5 | LEU A 5TYR A 83ALA A 18GLY A 14GLY A 30 | None | 1.13A | 3ou7D-1db3A:3.9 | 3ou7D-1db3A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ibj | CYSTATHIONINEBETA-LYASE (Arabidopsisthaliana) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 108TYR A 109TYR A 125ALA A 137LEU A 322 | None | 1.11A | 3ou7D-1ibjA:undetectable | 3ou7D-1ibjA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jf5 | ALPHA AMYLASE II (Thermoactinomycesvulgaris) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 5 | LEU A 426TYR A 576ALA A 439ASP A 456LEU A 417 | None | 1.17A | 3ou7D-1jf5A:undetectable | 3ou7D-1jf5A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mo0 | TRIOSEPHOSPHATEISOMERASE (Caenorhabditiselegans) |
PF00121(TIM) | 5 | ALA A 233GLY A 231TRP A 11SER A 210ASP A 214 | NoneSO4 A 901 ( 3.3A)NoneSO4 A 901 (-3.7A)None | 1.26A | 3ou7D-1mo0A:undetectable | 3ou7D-1mo0A:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzj | BETA-KETOACYLSYNTHASE III (Streptomycessp. R1128) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 322TYR A 324ALA A 122GLY A 317GLY A 319 | NoneNoneNoneNoneACE A 502 ( 3.9A) | 1.17A | 3ou7D-1mzjA:undetectable | 3ou7D-1mzjA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oq1 | PROTEIN YESU (Bacillussubtilis) |
PF09224(DUF1961) | 5 | LEU A 94ALA A 81GLY A 195GLY A 83ASP A 108 | None | 0.97A | 3ou7D-1oq1A:undetectable | 3ou7D-1oq1A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q18 | GLUCOKINASE (Escherichiacoli) |
PF02685(Glucokinase) | 5 | LEU A 306ALA A 15GLY A 11GLY A 8LEU A 17 | None | 1.26A | 3ou7D-1q18A:undetectable | 3ou7D-1q18A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnl | ALIPHATIC AMIDASEEXPRESSION-REGULATING PROTEIN (Pseudomonasaeruginosa) |
PF13433(Peripla_BP_5) | 5 | TYR A 119TYR A 104ALA A 123GLY A 121SER A 336 | None | 1.03A | 3ou7D-1qnlA:undetectable | 3ou7D-1qnlA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rpn | GDP-MANNOSE4,6-DEHYDRATASE (Pseudomonasaeruginosa) |
PF16363(GDP_Man_Dehyd) | 5 | LEU A 6TYR A 79ALA A 19GLY A 15GLY A 31 | None | 1.15A | 3ou7D-1rpnA:3.7 | 3ou7D-1rpnA:23.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tjr | BX1 (Zea mays) |
PF00290(Trp_syntA) | 5 | ALA A 338GLY A 340GLY A 129ASP A 126LEU A 125 | None | 1.22A | 3ou7D-1tjrA:undetectable | 3ou7D-1tjrA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuo | PUTATIVEPHOSPHOMANNOMUTASE (Thermusthermophilus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | LEU A 81ALA A 104GLY A 103GLY A 54LEU A 106 | None | 1.26A | 3ou7D-1tuoA:undetectable | 3ou7D-1tuoA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0z | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | ALA A 360GLY A 370MET A 383ASP A 363LEU A 362 | None | 1.10A | 3ou7D-1v0zA:undetectable | 3ou7D-1v0zA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve3 | HYPOTHETICAL PROTEINPH0226 (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 5 | ALA A 46GLY A 48SER A 69MET A 72ASP A 93 | SAM A 302 (-3.4A)SAM A 302 (-3.6A)SAM A 302 (-4.7A)SAM A 302 (-3.9A)SAM A 302 (-3.4A) | 0.65A | 3ou7D-1ve3A:17.2 | 3ou7D-1ve3A:27.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve3 | HYPOTHETICAL PROTEINPH0226 (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 5 | TYR A 7ALA A 46GLY A 48SER A 69MET A 72 | SAM A 302 (-4.6A)SAM A 302 (-3.4A)SAM A 302 (-3.6A)SAM A 302 (-4.7A)SAM A 302 (-3.9A) | 1.23A | 3ou7D-1ve3A:17.2 | 3ou7D-1ve3A:27.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzn | SAM-DEPENDENTMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 6 | TYR A 5TYR A 12ALA A 49GLY A 51MET A 75ASP A 96 | SAH A1001 (-3.5A)SAH A1001 (-4.9A)SAH A1001 (-3.4A)SAH A1001 (-3.1A)SAH A1001 (-4.4A)SAH A1001 (-3.3A) | 0.97A | 3ou7D-1wznA:19.0 | 3ou7D-1wznA:28.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8c | S-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Clostridiumacetobutylicum) |
PF13649(Methyltransf_25) | 5 | ALA A 46GLY A 48SER A 69MET A 72ASP A 93 | None | 0.61A | 3ou7D-1y8cA:18.3 | 3ou7D-1y8cA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avn | UBIQUINONE/MENAQUINONE BIOSYNTHESISMETHYLTRANSFERASE-RELATED PROTEIN (Thermotogamaritima) |
PF08241(Methyltransf_11) | 6 | TYR A 9TYR A 16GLY A 52TRP A 56SER A 73MET A 76 | SAI A1300 (-3.8A)SAI A1300 (-4.9A)SAI A1300 (-3.5A)NoneSAI A1300 (-4.7A)SAI A1300 ( 4.2A) | 0.69A | 3ou7D-2avnA:19.0 | 3ou7D-2avnA:26.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2det | TRNA-SPECIFIC2-THIOURIDYLASE MNMA (Escherichiacoli) |
PF03054(tRNA_Me_trans) | 5 | ALA A 125GLY A 11GLY A 127SER A 18MET A 12 | NoneNoneSO4 A5001 ( 3.8A)SO4 A5001 (-2.7A)None | 1.19A | 3ou7D-2detA:undetectable | 3ou7D-2detA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ehd | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY (Thermusthermophilus) |
PF00106(adh_short) | 5 | LEU A 42ALA A 22GLY A 18SER A 14LEU A 49 | NoneNoneNone CO A1001 (-3.0A)None | 1.23A | 3ou7D-2ehdA:6.3 | 3ou7D-2ehdA:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fiy | PROTEIN FDHE HOMOLOG (Pseudomonasaeruginosa) |
PF04216(FdhE) | 5 | LEU A 107TYR A 110ALA A 121GLY A 119LEU A 152 | None | 1.22A | 3ou7D-2fiyA:undetectable | 3ou7D-2fiyA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gs9 | HYPOTHETICAL PROTEINTT1324 (Thermusthermophilus) |
PF08241(Methyltransf_11) | 5 | TYR A 11GLY A 47TRP A 51SER A 66MET A 69 | NoneSAH A 301 (-3.5A)SAH A 301 (-4.6A)SAH A 301 (-4.5A)SAH A 301 (-4.2A) | 0.69A | 3ou7D-2gs9A:16.0 | 3ou7D-2gs9A:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h3g | BIOSYNTHETIC PROTEIN (Bacillusanthracis) |
PF03309(Pan_kinase) | 5 | LEU X 246ALA X 12GLY X 8SER X 63LEU X 14 | NoneNoneEDO X 501 (-3.6A)NoneNone | 1.17A | 3ou7D-2h3gX:undetectable | 3ou7D-2h3gX:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ifw | SCYTALIDOPEPSIN B (Scytalidiumlignicola) |
PF01828(Peptidase_A4) | 5 | TYR A 59ALA A 28GLY A 62GLY A 31SER A 32 | None | 1.19A | 3ou7D-2ifwA:undetectable | 3ou7D-2ifwA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jah | CLAVULANIC ACIDDEHYDROGENASE (Streptomycesclavuligerus) |
PF00106(adh_short) | 5 | LEU A 44ALA A 24GLY A 20SER A 16LEU A 51 | NoneNoneNoneNDP A1248 (-2.6A)None | 1.26A | 3ou7D-2jahA:5.9 | 3ou7D-2jahA:26.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jch | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF00912(Transgly) | 5 | TYR A 468ALA A 471GLY A 469GLY A 478MET A 616 | None | 1.23A | 3ou7D-2jchA:undetectable | 3ou7D-2jchA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m9p | SERINE PROTEASESUBUNIT NS2B, SERINEPROTEASE NS3 (Dengue virus) |
PF00949(Peptidase_S7)PF01002(Flavi_NS2B) | 5 | LEU A 210TYR A 222GLY A 194GLY A 197SER A 196 | None | 0.99A | 3ou7D-2m9pA:undetectable | 3ou7D-2m9pA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qny | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Mycobacteriumtuberculosis) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 308TYR A 310ALA A 113GLY A 303GLY A 305 | NoneNoneNoneNoneDFD A 760 (-3.6A) | 1.09A | 3ou7D-2qnyA:undetectable | 3ou7D-2qnyA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzz | N-METHYL-L-TRYPTOPHAN OXIDASE (Escherichiacoli) |
PF01266(DAO) | 5 | ALA A 16GLY A 18GLY A 11SER A 10MET A 30 | NoneNoneFAD A1373 (-3.4A)NoneNone | 1.04A | 3ou7D-2uzzA:2.2 | 3ou7D-2uzzA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 5 | LEU A 359GLY A 376SER A 323LEU A 361TRP A 338 | None | 1.25A | 3ou7D-2vsaA:undetectable | 3ou7D-2vsaA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9m | POLYMERASE X (Deinococcusradiodurans) |
PF14520(HHH_5)PF14716(HHH_8) | 5 | LEU A 154GLY A 104GLY A 101ASP A 98LEU A 99 | None | 1.23A | 3ou7D-2w9mA:undetectable | 3ou7D-2w9mA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqd | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Staphylococcusaureus) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 5 | ALA A 508GLY A 505GLY A 502SER A 452ASP A 523 | None | 1.24A | 3ou7D-2wqdA:undetectable | 3ou7D-2wqdA:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xlr | FLAVIN-CONTAININGMONOOXYGENASE (Methylophagaaminisulfidivorans) |
PF00743(FMO-like) | 5 | LEU A 229TYR A 240ALA A 214GLY A 218SER A 219 | None | 1.22A | 3ou7D-2xlrA:undetectable | 3ou7D-2xlrA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2n | VIRGINIAMYCIN BLYASE (Staphylococcusaureus) |
no annotation | 5 | LEU A 196ALA A 153GLY A 149SER A 150LEU A 154 | None | 1.03A | 3ou7D-2z2nA:undetectable | 3ou7D-2z2nA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z37 | CHITINASE (Brassica juncea) |
PF00182(Glyco_hydro_19) | 5 | ALA A 289GLY A 261SER A 266MET A 264LEU A 282 | None | 1.08A | 3ou7D-2z37A:undetectable | 3ou7D-2z37A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z37 | CHITINASE (Brassica juncea) |
PF00182(Glyco_hydro_19) | 5 | TYR A 258ALA A 289SER A 266MET A 264LEU A 282 | None | 1.12A | 3ou7D-2z37A:undetectable | 3ou7D-2z37A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zcv | UNCHARACTERIZEDOXIDOREDUCTASE YTFG (Escherichiacoli) |
PF05368(NmrA) | 5 | LEU A 112ALA A 161GLY A 164GLY A 250ASP A 246 | None | 1.26A | 3ou7D-2zcvA:5.2 | 3ou7D-2zcvA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bgk | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcusmutans) |
PF01256(Carb_kinase) | 5 | LEU A 101TYR A 36ALA A 39GLY A 37GLY A 31 | None | 1.25A | 3ou7D-3bgkA:4.5 | 3ou7D-3bgkA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bkw | S-ADENOSYLMETHIONINEDEPENDENTMETHYLTRANSFERASE (Mesorhizobiumjaponicum) |
PF08241(Methyltransf_11) | 5 | GLY A 52SER A 74MET A 77ASP A 96LEU A 97 | None | 0.67A | 3ou7D-3bkwA:16.9 | 3ou7D-3bkwA:25.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxo | N,N-DIMETHYLTRANSFERASE (Streptomycesvenezuelae) |
PF13649(Methyltransf_25) | 5 | ALA A 46GLY A 48SER A 69MET A 72ASP A 89 | SAM A 238 (-3.2A)SAM A 238 ( 3.7A)SAM A 238 (-4.6A)SAM A 238 (-4.2A)SAM A 238 (-3.0A) | 0.62A | 3ou7D-3bxoA:16.2 | 3ou7D-3bxoA:25.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dyj | TALIN-1 (Mus musculus) |
no annotation | 5 | LEU A2283ALA A2244GLY A2246GLY A2240LEU A2216 | None | 1.20A | 3ou7D-3dyjA:undetectable | 3ou7D-3dyjA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 5 | LEU A 14GLY A 53TRP A 107GLY A 73SER A 74 | SAM A 221 (-4.4A)SAM A 221 (-3.2A)NoneSAM A 221 (-3.2A)SAM A 221 (-4.6A) | 1.25A | 3ou7D-3e23A:18.9 | 3ou7D-3e23A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 6 | LEU A 14TYR A 17TYR A 24GLY A 53GLY A 73SER A 74 | SAM A 221 (-4.4A)SAM A 221 (-3.8A)SAM A 221 (-4.7A)SAM A 221 (-3.2A)SAM A 221 (-3.2A)SAM A 221 (-4.6A) | 0.89A | 3ou7D-3e23A:18.9 | 3ou7D-3e23A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnc | PUTATIVEACETYLTRANSFERASE (Listeriainnocua) |
PF13673(Acetyltransf_10) | 5 | TYR A 88TYR A 45ALA A 72GLY A 70LEU A 102 | EDO A 167 (-4.1A)MLI A 161 (-4.5A)NoneNoneNone | 1.24A | 3ou7D-3fncA:undetectable | 3ou7D-3fncA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fpz | THIAZOLEBIOSYNTHETIC ENZYME (Saccharomycescerevisiae) |
PF01946(Thi4) | 5 | ALA A 289GLY A 77SER A 75MET A 309LEU A 232 | NoneNoneAHZ A1100 (-3.6A)AHZ A1100 (-3.3A)None | 1.19A | 3ou7D-3fpzA:undetectable | 3ou7D-3fpzA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsx | TETRAHYDRODIPICOLINATEN-SUCCINYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF14602(Hexapep_2)PF14789(THDPS_M) | 5 | GLY A 247GLY A 245SER A 219MET A 221LEU A 260 | NoneNoneACY A 331 (-2.6A)NoneNone | 1.19A | 3ou7D-3fsxA:undetectable | 3ou7D-3fsxA:26.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gl3 | PUTATIVETHIOL:DISULFIDEINTERCHANGE PROTEINDSBE (Chlorobaculumtepidum) |
PF08534(Redoxin) | 5 | ALA A 35GLY A 142GLY A 32ASP A 30LEU A 29 | None | 1.23A | 3ou7D-3gl3A:undetectable | 3ou7D-3gl3A:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdy | UDP-GALACTOPYRANOSEMUTASE (Deinococcusradiodurans) |
PF03275(GLF)PF13450(NAD_binding_8) | 5 | TYR A 69TYR A 82ALA A 37GLY A 66LEU A 230 | NoneNoneNoneFAD A 450 (-3.4A)None | 1.13A | 3ou7D-3hdyA:undetectable | 3ou7D-3hdyA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l77 | SHORT-CHAIN ALCOHOLDEHYDROGENASE (Thermococcussibiricus) |
PF00106(adh_short) | 5 | LEU A 38ALA A 18GLY A 14SER A 10LEU A 45 | NoneNoneNoneNJP A 501 (-2.7A)None | 1.26A | 3ou7D-3l77A:5.4 | 3ou7D-3l77A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8d | METHYLTRANSFERASE (Bacillusthuringiensis) |
PF08241(Methyltransf_11) | 5 | GLY A 63SER A 84MET A 87ASP A 106LEU A 107 | None | 1.02A | 3ou7D-3l8dA:14.3 | 3ou7D-3l8dA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lsc | TRIAZINE HYDROLASE (Paenarthrobacteraurescens) |
PF01979(Amidohydro_1) | 5 | TYR A 67ALA A 328GLY A 69GLY A 326TRP A 85 | AOO A 457 (-4.7A)NoneNoneNoneNone | 1.18A | 3ou7D-3lscA:undetectable | 3ou7D-3lscA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3now | UNC-45 PROTEIN,SD10334P (Drosophilamelanogaster) |
PF11701(UNC45-central) | 5 | LEU A 585TYR A 542ALA A 537GLY A 539LEU A 563 | None | 1.18A | 3ou7D-3nowA:undetectable | 3ou7D-3nowA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nz4 | PHENYLALANINEAMMONIA-LYASE (Taxuscanadensis) |
PF00221(Lyase_aromatic) | 5 | TYR A 245ALA A 247SER A 241ASP A 473LEU A 476 | None | 1.21A | 3ou7D-3nz4A:undetectable | 3ou7D-3nz4A:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3okz | PUTATIVEUNCHARACTERIZEDPROTEIN GBS0355 (Streptococcusagalactiae) |
PF03816(LytR_cpsA_psr) | 5 | ALA A 130GLY A 132GLY A 80SER A 79ASP A 68 | None | 1.24A | 3ou7D-3okzA:undetectable | 3ou7D-3okzA:22.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ou6 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptomycesluridus) |
PF13649(Methyltransf_25) | 12 | LEU A 12TYR A 15TYR A 22ALA A 54GLY A 56TRP A 60GLY A 76SER A 77MET A 80ASP A 98LEU A 99TRP A 116 | SAM A 300 ( 3.9A)SAM A 300 ( 3.5A)SAM A 300 (-4.4A)SAM A 300 (-3.4A)SAM A 300 (-3.1A)NoneSAM A 300 (-3.3A)SAM A 300 (-4.5A)SAM A 300 (-4.0A)SAM A 300 (-4.0A)SAM A 300 (-3.9A)None | 0.12A | 3ou7D-3ou6A:39.6 | 3ou7D-3ou6A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pei | CYTOSOLAMINOPEPTIDASE (Francisellatularensis) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 5 | TYR A 372GLY A 374GLY A 451SER A 452ASP A 456 | None | 1.16A | 3ou7D-3peiA:undetectable | 3ou7D-3peiA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3px2 | N-METHYLTRANSFERASE (Streptomycesfradiae) |
PF13649(Methyltransf_25) | 7 | TYR A 14TYR A 22ALA A 58GLY A 60SER A 81MET A 84ASP A 101 | SAH A 263 ( 3.9A)SAH A 263 (-4.6A)SAH A 263 (-3.5A)SAH A 263 (-3.3A)SAH A 263 (-4.7A)SAH A 263 (-4.5A)SAH A 263 (-3.5A) | 0.95A | 3ou7D-3px2A:17.1 | 3ou7D-3px2A:28.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q98 | TRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 159ALA A 118GLY A 63GLY A 120SER A 65 | None | 1.10A | 3ou7D-3q98A:2.4 | 3ou7D-3q98A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti7 | BASIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE BPRV (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 5 | LEU A 325ALA A 249GLY A 251GLY A 227LEU A 247 | None | 1.21A | 3ou7D-3ti7A:undetectable | 3ou7D-3ti7A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4y | SERINE/THREONINE-PROTEIN PHOSPHATASEPP1-ALPHA CATALYTICSUBUNIT (Homo sapiens) |
PF00149(Metallophos)PF16891(STPPase_N) | 5 | LEU A 75TYR A 255ALA A 279GLY A 254SER A 268 | None | 1.16A | 3ou7D-3v4yA:undetectable | 3ou7D-3v4yA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w15 | PEROXISOMALTARGETING SIGNAL 2RECEPTOR (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | LEU A 216ALA A 223GLY A 240GLY A 220SER A 219 | NO3 A 401 (-4.4A)NoneNoneNoneNone | 0.97A | 3ou7D-3w15A:undetectable | 3ou7D-3w15A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 5 | LEU A 937ALA A 981GLY A 985GLY A 403ASP A 407 | None | 1.23A | 3ou7D-3w9hA:undetectable | 3ou7D-3w9hA:12.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a6u | OMEGA TRANSAMINASE (Chromobacteriumviolaceum) |
PF00202(Aminotran_3) | 5 | TYR A 116ALA A 286GLY A 298GLY A 289SER A 291 | None | 1.27A | 3ou7D-4a6uA:undetectable | 3ou7D-4a6uA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmv | SHORT-CHAINDEHYDROGENASE (Sphingobiumyanoikuyae) |
PF00106(adh_short) | 5 | LEU A 41ALA A 21GLY A 17SER A 13LEU A 48 | NoneNoneNoneNAP A 300 (-2.8A)None | 1.23A | 3ou7D-4bmvA:5.9 | 3ou7D-4bmvA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6e | CELL DIVISIONPROTEIN FTSZ (Thermobifidafusca) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | ALA A 100GLY A 107GLY A 19ASP A 184LEU A 187 | NoneSO4 A 607 (-3.4A)NoneNoneNone | 1.21A | 3ou7D-4e6eA:2.7 | 3ou7D-4e6eA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emi | TODA (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | LEU A 394ALA A 350GLY A 349GLY A 344LEU A 352 | None | 1.12A | 3ou7D-4emiA:undetectable | 3ou7D-4emiA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl3 | TYROSINE-PROTEINKINASE SYK (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | LEU A 365TYR A 364ALA A 421GLY A 437LEU A 446 | None | 1.11A | 3ou7D-4fl3A:undetectable | 3ou7D-4fl3A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jrm | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Vibrio cholerae) |
no annotation | 5 | LEU D 168GLY D 280GLY D 407SER D 408MET D 284 | None | 1.23A | 3ou7D-4jrmD:undetectable | 3ou7D-4jrmD:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mrp | ABC TRANSPORTERRELATED PROTEIN (Novosphingobiumaromaticivorans) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | LEU A 588TYR A 589GLY A 577ASP A 569LEU A 568 | None | 1.27A | 3ou7D-4mrpA:undetectable | 3ou7D-4mrpA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q29 | PLU4264 PROTEIN (Photorhabduslaumondii) |
PF07883(Cupin_2) | 5 | GLY A 36GLY A 21SER A 22ASP A 20LEU A 19 | None | 1.19A | 3ou7D-4q29A:undetectable | 3ou7D-4q29A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdk | MAGNESIUM-PROTOPORPHYRINO-METHYLTRANSFERASE (Synechocystissp. PCC 6803) |
PF07109(Mg-por_mtran_C) | 5 | GLY A 72SER A 93MET A 96ASP A 120LEU A 121 | SAH A 301 (-3.6A)SAH A 301 (-4.6A)SAH A 301 (-4.2A)SAH A 301 (-3.8A)SAH A 301 (-3.6A) | 1.06A | 3ou7D-4qdkA:17.0 | 3ou7D-4qdkA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qtu | PUTATIVEMETHYLTRANSFERASEBUD23 (Saccharomycescerevisiae) |
PF08241(Methyltransf_11) | 5 | TYR B 22GLY B 57SER B 79MET B 82ASP B 99 | SAM B 301 (-4.6A)SAM B 301 (-3.3A)EDO B 310 ( 3.0A)SAM B 301 (-4.4A)SAM B 301 (-3.7A) | 0.57A | 3ou7D-4qtuB:15.6 | 3ou7D-4qtuB:25.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvo | MALATE DEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ALA A 252GLY A 129SER A 155MET A 267LEU A 87 | None | 1.23A | 3ou7D-4tvoA:4.1 | 3ou7D-4tvoA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | LEU B 330ALA B 249GLY B 354ASP B 252LEU B 251 | None | 1.27A | 3ou7D-4xcgB:undetectable | 3ou7D-4xcgB:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpi | PUTATIVEOXIDASE/HYDROXYLASE (Streptomyceshygroscopicus) |
PF05721(PhyH) | 5 | LEU A 36ALA A 221GLY A 88GLY A 90LEU A 219 | None | 1.18A | 3ou7D-4zpiA:undetectable | 3ou7D-4zpiA:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bsz | N-METHYLTRANSFERASE (Streptoalloteichussp. ATCC 53650) |
PF13649(Methyltransf_25) | 5 | ALA A 53GLY A 55SER A 76MET A 79ASP A 96 | SAH A 301 (-3.3A)SAH A 301 ( 3.7A)SAH A 301 (-4.6A)SAH A 301 ( 4.4A)SAH A 301 (-3.7A) | 0.75A | 3ou7D-5bszA:15.5 | 3ou7D-5bszA:26.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyt | ADENYLOSUCCINATELYASE (Schistosomamansoni) |
PF00206(Lyase_1)PF10397(ADSL_C) | 5 | LEU A 206ALA A 193GLY A 195GLY A 103LEU A 40 | None | 1.06A | 3ou7D-5eytA:undetectable | 3ou7D-5eytA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h02 | GLYCINE SARCOSINEN-METHYLTRANSFERASE (Methanohalophilusportucalensis) |
PF13649(Methyltransf_25) | 6 | ALA A 67GLY A 69GLY A 89SER A 90MET A 93ASP A 114 | SAH A 301 (-3.9A)SAH A 301 (-3.3A)SAH A 301 (-3.4A)SAH A 301 ( 4.9A)SAH A 301 (-3.9A)SAH A 301 (-3.7A) | 0.42A | 3ou7D-5h02A:16.9 | 3ou7D-5h02A:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 5 | LEU A 225TYR A 157GLY A 153GLY A 177SER A 178 | None | 1.04A | 3ou7D-5h42A:undetectable | 3ou7D-5h42A:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik8 | LAMININ SUBUNITALPHA-2 (Mus musculus) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 5 | TYR A2820GLY A2817GLY A2796SER A2795LEU A2798 | None | 1.21A | 3ou7D-5ik8A:undetectable | 3ou7D-5ik8A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5je3 | METHYL TRANSFERASE (Burkholderiaglumae) |
PF13847(Methyltransf_31) | 5 | ALA A 47GLY A 49SER A 71MET A 74ASP A 95 | SAH A 301 (-3.2A)SAH A 301 (-3.6A)SAH A 301 ( 4.8A)SAH A 301 ( 4.5A)SAH A 301 (-3.7A) | 0.52A | 3ou7D-5je3A:16.2 | 3ou7D-5je3A:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5leb | DDD_D12_06_D12_06_D12 (syntheticconstruct) |
PF12796(Ank_2)PF13857(Ank_5) | 5 | ALA A 54GLY A 58TRP A 56GLY A 61LEU A 66 | None | 1.25A | 3ou7D-5lebA:undetectable | 3ou7D-5lebA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5leb | DDD_D12_06_D12_06_D12 (syntheticconstruct) |
PF12796(Ank_2)PF13857(Ank_5) | 5 | ALA A 206GLY A 210TRP A 208GLY A 213LEU A 218 | None | 1.23A | 3ou7D-5lebA:undetectable | 3ou7D-5lebA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2p | TRYPTOPHAN SYNTHASEALPHA CHAIN (Sulfolobussolfataricus) |
no annotation | 5 | LEU A 238TYR A 241ALA A 201GLY A 205GLY A 208 | None | 0.96A | 3ou7D-5n2pA:undetectable | 3ou7D-5n2pA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5onu | OUTER MEMBRANEPROTEIN OMPU (Vibrio cholerae) |
no annotation | 5 | LEU A 138ALA A 219GLY A 231GLY A 233LEU A 217 | None | 1.13A | 3ou7D-5onuA:undetectable | 3ou7D-5onuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7x | NOD FACTOR BINDINGLECTIN-NUCLEOTIDEPHOSPHOHYDROLASE (Vignaunguiculata) |
PF01150(GDA1_CD39) | 5 | LEU F 94ALA F 87GLY F 14SER F 49LEU F 103 | NoneNonePO4 F 502 (-3.4A)NoneNone | 1.01A | 3ou7D-5u7xF:undetectable | 3ou7D-5u7xF:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uao | TRYPTOPHANE-5-HALOGENASE (Microbisporasp. ATCCPTA-5024) |
PF04820(Trp_halogenase) | 5 | LEU A 103ALA A 499GLY A 502ASP A 121LEU A 144 | None | 1.13A | 3ou7D-5uaoA:3.5 | 3ou7D-5uaoA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5voc | ENVELOPEGLYCOPROTEIN H (Humanbetaherpesvirus5) |
PF02489(Herpes_glycop_H)PF17488(Herpes_glycoH_C) | 5 | ALA A 351GLY A 185SER A 184ASP A 146LEU A 309 | None | 1.22A | 3ou7D-5vocA:undetectable | 3ou7D-5vocA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmj | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Desulfovibriogigas) |
no annotation | 5 | LEU A 579ALA A 536GLY A 538MET A 251ASP A 541 | None | 1.08A | 3ou7D-5xmjA:undetectable | 3ou7D-5xmjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | ALA B 407GLY B 238SER B 239ASP B 48LEU B 49 | None | 1.26A | 3ou7D-5xogB:undetectable | 3ou7D-5xogB:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 5 | LEU A1177ALA A1230GLY A1226GLY A1217MET A1221 | None | 1.16A | 3ou7D-6bq1A:undetectable | 3ou7D-6bq1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfz | DAD2HSK3 (Chaetomiumthermophilum;Chaetomiumthermophilum) |
no annotationno annotation | 5 | LEU G 62GLY G 68GLY G 63SER G 64TRP C 80 | None | 1.18A | 3ou7D-6cfzG:undetectable | 3ou7D-6cfzG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehc | OUTER MEMBRANEPROTEIN U (Vibrio cholerae) |
no annotation | 5 | LEU A 108ALA A 189GLY A 201GLY A 203LEU A 187 | None | 1.14A | 3ou7D-6ehcA:undetectable | 3ou7D-6ehcA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5z | 24-STEROLC-METHYLTRANSFERASE (Haloferaxvolcanii) |
no annotation | 5 | GLY A 48GLY A 70SER A 71MET A 74ASP A 93 | SAH A 301 ( 3.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.0A)SAH A 301 (-3.8A) | 0.54A | 3ou7D-6f5zA:17.1 | 3ou7D-6f5zA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5z | 24-STEROLC-METHYLTRANSFERASE (Haloferaxvolcanii) |
no annotation | 5 | GLY A 48TRP A 108GLY A 70SER A 71MET A 74 | SAH A 301 ( 3.7A)NoneSAH A 301 (-3.6A)NoneSAH A 301 (-4.0A) | 1.19A | 3ou7D-6f5zA:17.1 | 3ou7D-6f5zA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fb3 | TENEURIN-2 (Gallus gallus) |
no annotation | 5 | ALA A1566GLY A1543GLY A1561SER A1560ASP A1563 | None | 1.18A | 3ou7D-6fb3A:undetectable | 3ou7D-6fb3A:undetectable |