SIMILAR PATTERNS OF AMINO ACIDS FOR 3OU6_D_SAMD300
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b4e | PROTEIN(5-AMINOLEVULINICACID DEHYDRATASE) (Escherichiacoli) |
PF00490(ALAD) | 5 | LEU A 26GLU A 319ALA A 318ASP A 30LEU A 28 | GOL A 409 ( 4.7A)NoneNoneNoneNone | 1.38A | 3ou6D-1b4eA:undetectable | 3ou6D-1b4eA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1boo | PROTEIN (N-4CYTOSINE-SPECIFICMETHYLTRANSFERASEPVU II) (Proteusvulgaris) |
PF01555(N6_N4_Mtase) | 5 | LEU A 330TYR A 23GLU A 298ALA A 301ASP A 319 | None | 1.43A | 3ou6D-1booA:3.4 | 3ou6D-1booA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cem | CELLULASE CELA(1,4-BETA-D-GLUCAN-GLUCANOHYDROLASE) (Ruminiclostridiumthermocellum) |
PF01270(Glyco_hydro_8) | 5 | LEU A 350TYR A 41TRP A 284GLY A 347ASP A 349 | None | 0.99A | 3ou6D-1cemA:undetectable | 3ou6D-1cemA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dp2 | RHODANESE (Bos taurus) |
PF00581(Rhodanese) | 5 | TYR A 98GLU A 136GLY A 104SER A 105ASP A 102 | None | 1.17A | 3ou6D-1dp2A:undetectable | 3ou6D-1dp2A:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dtp | DIPHTHERIA TOXIN (Corynephagebeta) |
PF02763(Diphtheria_C) | 5 | GLU A 168ALA A 77GLY A 75SER A 74ASP A 176 | None | 1.32A | 3ou6D-1dtpA:undetectable | 3ou6D-1dtpA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fzd | FIBRINOGEN-420 (Homo sapiens) |
PF00147(Fibrinogen_C) | 5 | ALA A 796GLY A 750SER A 751ASP A 745LEU A 747 | None | 1.35A | 3ou6D-1fzdA:undetectable | 3ou6D-1fzdA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ibj | CYSTATHIONINEBETA-LYASE (Arabidopsisthaliana) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 108TYR A 109TYR A 125ALA A 137LEU A 322 | None | 1.11A | 3ou6D-1ibjA:1.9 | 3ou6D-1ibjA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jf5 | ALPHA AMYLASE II (Thermoactinomycesvulgaris) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 5 | LEU A 426TYR A 576ALA A 439ASP A 456LEU A 417 | None | 1.15A | 3ou6D-1jf5A:undetectable | 3ou6D-1jf5A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbl | PYRUVATE PHOSPHATEDIKINASE ([Clostridium]symbiosum) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | GLU A 279ALA A 276GLY A 252SER A 251LEU A 273 | None | 1.37A | 3ou6D-1kblA:undetectable | 3ou6D-1kblA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1koa | TWITCHIN (Caenorhabditiselegans) |
PF00069(Pkinase)PF07679(I-set) | 5 | ALA A6088GLY A6085SER A6243ASP A6063LEU A6062 | None | 1.37A | 3ou6D-1koaA:undetectable | 3ou6D-1koaA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qon | ACETYLCHOLINESTERASE (Drosophilamelanogaster) |
PF00135(COesterase) | 5 | TYR A 447ALA A 246SER A 241MET A 262LEU A 208 | None | 1.44A | 3ou6D-1qonA:undetectable | 3ou6D-1qonA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r03 | MITOCHONDRIALFERRITIN (Homo sapiens) |
PF00210(Ferritin) | 5 | TYR A 54TYR A 34GLY A 96MET A 37LEU A 97 | None | 1.41A | 3ou6D-1r03A:undetectable | 3ou6D-1r03A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rjc | CAMELID HEAVY CHAINANTIBODY (Camelusdromedarius) |
PF07686(V-set) | 5 | LEU A 18TYR A 94ALA A 6TRP A 118GLY A 8 | None | 1.44A | 3ou6D-1rjcA:undetectable | 3ou6D-1rjcA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sq5 | PANTOTHENATE KINASE (Escherichiacoli) |
PF00485(PRK) | 5 | LEU A1201GLU A1295GLY A1095SER A1096LEU A1204 | None | 1.42A | 3ou6D-1sq5A:undetectable | 3ou6D-1sq5A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tc1 | PROTEIN(HYPOXANTHINEPHOSPHORIBOSYLTRANSFERASE) (Trypanosomacruzi) |
PF00156(Pribosyltran) | 5 | TYR A 5GLU A 15GLY A 169ASP A 112LEU A 140 | NoneNoneNoneMES A 800 ( 4.0A)None | 1.37A | 3ou6D-1tc1A:2.2 | 3ou6D-1tc1A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzn | SAM-DEPENDENTMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 5 | TYR A 5TYR A 12ALA A 49MET A 75ASP A 96 | SAH A1001 (-3.5A)SAH A1001 (-4.9A)SAH A1001 (-3.4A)SAH A1001 (-4.4A)SAH A1001 (-3.3A) | 1.04A | 3ou6D-1wznA:18.9 | 3ou6D-1wznA:28.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avn | UBIQUINONE/MENAQUINONE BIOSYNTHESISMETHYLTRANSFERASE-RELATED PROTEIN (Thermotogamaritima) |
PF08241(Methyltransf_11) | 5 | TYR A 9TYR A 16TRP A 56SER A 73MET A 76 | SAI A1300 (-3.8A)SAI A1300 (-4.9A)NoneSAI A1300 (-4.7A)SAI A1300 ( 4.2A) | 0.78A | 3ou6D-2avnA:19.0 | 3ou6D-2avnA:26.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bvg | 6-HYDROXY-D-NICOTINEOXIDASE (Paenarthrobacternicotinovorans) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | TYR A 293GLU A 117ALA A 118GLY A 122LEU A 202 | None | 1.46A | 3ou6D-2bvgA:undetectable | 3ou6D-2bvgA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gs9 | HYPOTHETICAL PROTEINTT1324 (Thermusthermophilus) |
PF08241(Methyltransf_11) | 5 | TYR A 11GLU A 43TRP A 51SER A 66MET A 69 | NoneSAH A 301 (-3.8A)SAH A 301 (-4.6A)SAH A 301 (-4.5A)SAH A 301 (-4.2A) | 0.85A | 3ou6D-2gs9A:16.0 | 3ou6D-2gs9A:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hqo | PUTATIVETRANSCRIPTIONALREGULATOR (Helicobacterpylori) |
PF00072(Response_reg) | 5 | GLU A 82ALA A 86GLY A 90SER A 60ASP A 92 | None | 1.42A | 3ou6D-2hqoA:undetectable | 3ou6D-2hqoA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ozo | TYROSINE-PROTEINKINASE ZAP-70 (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | TYR A 178GLU A 172ALA A 173SER A 179LEU A 188 | None | 1.44A | 3ou6D-2ozoA:undetectable | 3ou6D-2ozoA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcq | PUTATIVEDIHYDRODIPICOLINATESYNTHASE (Thermusthermophilus) |
PF00701(DHDPS) | 5 | LEU A 36GLU A 83ALA A 84GLY A 68LEU A 92 | None | 1.34A | 3ou6D-2pcqA:undetectable | 3ou6D-2pcqA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1y | CELL DIVISIONPROTEIN FTSZ (Mycobacteriumtuberculosis) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | GLU A 102ALA A 100GLY A 19ASP A 184LEU A 187 | NoneNoneGSP A 401 (-3.6A)GSP A 401 (-3.1A)None | 1.43A | 3ou6D-2q1yA:3.1 | 3ou6D-2q1yA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4i | UNCHARACTERIZEDPROTEIN (Cytophagahutchinsonii) |
PF14534(DUF4440) | 5 | TYR A 53GLU A 88ALA A 59GLY A 56SER A 55 | IPA A 127 (-4.6A)NoneNoneNoneNone | 1.22A | 3ou6D-2r4iA:undetectable | 3ou6D-2r4iA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 5 | LEU A 359GLY A 376SER A 323LEU A 361TRP A 338 | None | 1.24A | 3ou6D-2vsaA:undetectable | 3ou6D-2vsaA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9x | PUTATIVE ACETYLXYLAN ESTERASE (Cellvibriojaponicus) |
PF00657(Lipase_GDSL) | 5 | LEU A 244GLU A 257GLY A 201SER A 214ASP A 150 | None | 1.42A | 3ou6D-2w9xA:undetectable | 3ou6D-2w9xA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xlr | FLAVIN-CONTAININGMONOOXYGENASE (Methylophagaaminisulfidivorans) |
PF00743(FMO-like) | 5 | LEU A 229TYR A 240ALA A 214GLY A 218SER A 219 | None | 1.19A | 3ou6D-2xlrA:undetectable | 3ou6D-2xlrA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yys | PROLINEIMINOPEPTIDASE-RELATED PROTEIN (Thermusthermophilus) |
PF12697(Abhydrolase_6) | 5 | GLU A 12ALA A 13GLY A 62ASP A 59LEU A 15 | None | 1.23A | 3ou6D-2yysA:2.2 | 3ou6D-2yysA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z37 | CHITINASE (Brassica juncea) |
PF00182(Glyco_hydro_19) | 5 | TYR A 258ALA A 289SER A 266MET A 264LEU A 282 | None | 1.09A | 3ou6D-2z37A:undetectable | 3ou6D-2z37A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwf | ALKALINE PHOSPHATASESYNTHESIS SENSORPROTEIN PHOR (Bacillussubtilis) |
PF16736(sCache_like) | 5 | TYR A 90ALA A 71GLY A 73ASP A 76LEU A 75 | None | 1.44A | 3ou6D-3cwfA:undetectable | 3ou6D-3cwfA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 5 | LEU A 14TYR A 17TYR A 24GLU A 49GLY A 73 | SAM A 221 (-4.4A)SAM A 221 (-3.8A)SAM A 221 (-4.7A)NoneSAM A 221 (-3.2A) | 1.02A | 3ou6D-3e23A:18.9 | 3ou6D-3e23A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 5 | LEU A 14TYR A 24GLU A 49GLY A 73SER A 74 | SAM A 221 (-4.4A)SAM A 221 (-4.7A)NoneSAM A 221 (-3.2A)SAM A 221 (-4.6A) | 0.78A | 3ou6D-3e23A:18.9 | 3ou6D-3e23A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnc | PUTATIVEACETYLTRANSFERASE (Listeriainnocua) |
PF13673(Acetyltransf_10) | 5 | LEU A 89TYR A 88TYR A 45ALA A 72GLY A 70 | EDO A 165 (-4.9A)EDO A 167 (-4.1A)MLI A 161 (-4.5A)NoneNone | 1.38A | 3ou6D-3fncA:undetectable | 3ou6D-3fncA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fru | NEONATAL FC RECEPTOR (Rattusnorvegicus) |
PF00129(MHC_I)PF07654(C1-set) | 5 | LEU A 242GLU A 257GLY A 222SER A 223LEU A 215 | None | 1.28A | 3ou6D-3fruA:undetectable | 3ou6D-3fruA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fz0 | NUCLEOSIDEHYDROLASE, PUTATIVE (Trypanosomabrucei) |
PF01156(IU_nuc_hydro) | 5 | TYR A 57ALA A 19MET A 24ASP A 9LEU A 131 | None | 1.42A | 3ou6D-3fz0A:2.5 | 3ou6D-3fz0A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gt7 | SENSOR PROTEIN (Syntrophusaciditrophicus) |
PF00072(Response_reg) | 5 | LEU A 83GLU A 46ALA A 47SER A 52LEU A 15 | None | 1.22A | 3ou6D-3gt7A:2.1 | 3ou6D-3gt7A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7n | NUCLEOPORIN NUP120 (Saccharomycescerevisiae) |
PF11715(Nup160) | 5 | LEU A 205TYR A 204GLY A 181LEU A 183TRP A 246 | None | 1.28A | 3ou6D-3h7nA:undetectable | 3ou6D-3h7nA:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kci | PROBABLE E3UBIQUITIN-PROTEINLIGASE HERC2 (Homo sapiens) |
PF00415(RCC1) | 5 | LEU A4132GLU A4065ALA A4066GLY A4069LEU A4071 | None | 1.34A | 3ou6D-3kciA:undetectable | 3ou6D-3kciA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmk | METABOTROPICGLUTAMATE RECEPTOR 5 (Homo sapiens) |
PF01094(ANF_receptor) | 5 | TYR A 481GLU A 320ALA A 321GLY A 323LEU A 301 | None | 1.15A | 3ou6D-3lmkA:undetectable | 3ou6D-3lmkA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkr | COATOMER SUBUNITALPHA (Bos taurus) |
PF06957(COPI_C) | 5 | LEU B1001ALA B1050SER B1035ASP B1005LEU B1003 | None | 1.43A | 3ou6D-3mkrB:undetectable | 3ou6D-3mkrB:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nr8 | PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
no annotation | 5 | LEU B 585ALA B 543GLY B 545SER B 528TRP B 604 | None | 1.36A | 3ou6D-3nr8B:undetectable | 3ou6D-3nr8B:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nz4 | PHENYLALANINEAMMONIA-LYASE (Taxuscanadensis) |
PF00221(Lyase_aromatic) | 5 | TYR A 245ALA A 247SER A 241ASP A 473LEU A 476 | None | 1.20A | 3ou6D-3nz4A:undetectable | 3ou6D-3nz4A:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3on2 | PROBABLETRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF00440(TetR_N)PF13305(WHG) | 5 | LEU A 107GLU A 76GLY A 67SER A 66LEU A 71 | None | 1.42A | 3ou6D-3on2A:undetectable | 3ou6D-3on2A:25.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ou6 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptomycesluridus) |
PF13649(Methyltransf_25) | 12 | LEU A 12TYR A 15TYR A 22GLU A 52ALA A 54TRP A 60GLY A 76SER A 77MET A 80ASP A 98LEU A 99TRP A 116 | SAM A 300 ( 3.9A)SAM A 300 ( 3.5A)SAM A 300 (-4.4A)NoneSAM A 300 (-3.4A)NoneSAM A 300 (-3.3A)SAM A 300 (-4.5A)SAM A 300 (-4.0A)SAM A 300 (-4.0A)SAM A 300 (-3.9A)None | 0.19A | 3ou6D-3ou6A:39.5 | 3ou6D-3ou6A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pa8 | TOXIN B (Clostridioidesdifficile) |
PF11713(Peptidase_C80) | 5 | LEU A 26ALA A 50GLY A 207SER A 205LEU A 54 | None621 A 300 ( 4.1A)NoneNoneNone | 1.38A | 3ou6D-3pa8A:undetectable | 3ou6D-3pa8A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3px2 | N-METHYLTRANSFERASE (Streptomycesfradiae) |
PF13649(Methyltransf_25) | 6 | TYR A 14TYR A 22ALA A 58SER A 81MET A 84ASP A 101 | SAH A 263 ( 3.9A)SAH A 263 (-4.6A)SAH A 263 (-3.5A)SAH A 263 (-4.7A)SAH A 263 (-4.5A)SAH A 263 (-3.5A) | 0.99A | 3ou6D-3px2A:17.1 | 3ou6D-3px2A:28.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdf | DIHYDRODIPICOLINATESYNTHASE (Acinetobacterbaumannii) |
PF00701(DHDPS) | 5 | ALA A 221GLY A 4SER A 5MET A 214ASP A 200 | None | 1.38A | 3ou6D-3tdfA:undetectable | 3ou6D-3tdfA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tth | SPERMIDINEN1-ACETYLTRANSFERASE (Coxiellaburnetii) |
PF13302(Acetyltransf_3) | 5 | LEU A 75TYR A 136GLU A 103ALA A 104LEU A 9 | None | 1.06A | 3ou6D-3tthA:undetectable | 3ou6D-3tthA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugk | SACCHAROPINEDEHYDROGENASE [NAD+,L-LYSINE-FORMING] (Saccharomycescerevisiae) |
PF05222(AlaDh_PNT_N) | 5 | ALA A 144GLY A 208SER A 205ASP A 211LEU A 212 | None | 1.36A | 3ou6D-3ugkA:undetectable | 3ou6D-3ugkA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4p | INTEGRIN ALPHA-4 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | LEU A 25GLU A 351GLY A 403SER A 402ASP A 414 | NoneNoneNoneNone CA A 603 (-2.8A) | 1.30A | 3ou6D-3v4pA:undetectable | 3ou6D-3v4pA:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3viu | PHOSPHORIBOSYLFORMYLGLYCINAMIDINESYNTHASE 2 (Thermusthermophilus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | GLU A 243ALA A 244GLY A 325ASP A 330LEU A 329 | None | 1.43A | 3ou6D-3viuA:undetectable | 3ou6D-3viuA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vjz | PUTATIVEUNCHARACTERIZEDPROTEIN (Neisseriameningitidis) |
PF14300(DUF4375) | 5 | TYR A 53GLU A 111ALA A 68ASP A 119LEU A 123 | None | 1.44A | 3ou6D-3vjzA:undetectable | 3ou6D-3vjzA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5a | NUCLEOSIDE-TRIPHOSPHATASE 1 (Toxoplasmagondii) |
PF01150(GDA1_CD39) | 5 | LEU A 453GLU A 277ALA A 283SER A 332MET A 329 | None MG A 701 (-4.7A)NoneNoneANP A 700 (-4.8A) | 1.38A | 3ou6D-4a5aA:undetectable | 3ou6D-4a5aA:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d0y | DACB (Streptococcuspneumoniae) |
PF02557(VanY) | 5 | GLU A 152ALA A 76SER A 65ASP A 62LEU A 82 | NoneNoneNone ZN A1241 ( 2.4A)None | 1.45A | 3ou6D-4d0yA:undetectable | 3ou6D-4d0yA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl3 | TYROSINE-PROTEINKINASE SYK (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | LEU A 365TYR A 364ALA A 421GLY A 437LEU A 446 | None | 1.11A | 3ou6D-4fl3A:undetectable | 3ou6D-4fl3A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl3 | TYROSINE-PROTEINKINASE SYK (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | LEU A 365TYR A 364GLU A 420ALA A 421LEU A 446 | None | 1.17A | 3ou6D-4fl3A:undetectable | 3ou6D-4fl3A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gb7 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Bacillusanthracis) |
PF00144(Beta-lactamase) | 5 | TYR A 246TYR A 352GLY A 249SER A 250LEU A 208 | NO3 A 601 (-4.3A)NoneNoneNoneNone | 1.45A | 3ou6D-4gb7A:undetectable | 3ou6D-4gb7A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ipe | TNFRECEPTOR-ASSOCIATEDPROTEIN 1 (Danio rerio) |
PF00183(HSP90)PF13589(HATPase_c_3) | 5 | LEU A 113GLU A 255GLY A 252SER A 251TRP A 246 | None | 1.25A | 3ou6D-4ipeA:undetectable | 3ou6D-4ipeA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ius | GCN5-RELATEDN-ACETYLTRANSFERASE (Kribbellaflavida) |
PF00583(Acetyltransf_1) | 5 | LEU A 254TYR A 142GLU A 77GLY A 248LEU A 74 | None | 1.38A | 3ou6D-4iusA:undetectable | 3ou6D-4iusA:25.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6c | CYTOCHROME P450MONOOXYGENASE (Nocardiafarcinica) |
PF00067(p450) | 5 | TYR A 176SER A 159MET A 155ASP A 214LEU A 215 | None | 1.17A | 3ou6D-4j6cA:undetectable | 3ou6D-4j6cA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jj3 | MAMP (Magnetococcusmarinus) |
PF13180(PDZ_2) | 5 | LEU A 116GLU A 156ALA A 141GLY A 118LEU A 139 | None | 1.41A | 3ou6D-4jj3A:undetectable | 3ou6D-4jj3A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l52 | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 7,TGF-BETA-ACTIVATEDKINASE 1 ANDMAP3K7-BINDINGPROTEIN 1 CHIMERA (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | ALA A 236TRP A 241GLY A 191SER A 192MET A 196 | None | 1.45A | 3ou6D-4l52A:undetectable | 3ou6D-4l52A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n77 | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
PF09704(Cas_Cas5d) | 5 | LEU A 130GLU A 180ALA A 178GLY A 129LEU A 5 | None | 1.42A | 3ou6D-4n77A:undetectable | 3ou6D-4n77A:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nt9 | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
no annotation | 5 | GLU B 152ALA B 76SER B 65ASP B 62LEU B 82 | None | 1.44A | 3ou6D-4nt9B:undetectable | 3ou6D-4nt9B:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 5 | LEU A1182GLU A1110ALA A1158GLY A1139ASP A1615 | None | 1.44A | 3ou6D-4o9xA:undetectable | 3ou6D-4o9xA:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofq | PUTATIVE CELLSURFACE PROTEIN (Streptococcuspyogenes) |
PF16364(Antigen_C) | 5 | TYR A1288ALA A1270TRP A1184ASP A1234LEU A1235 | None | 1.37A | 3ou6D-4ofqA:undetectable | 3ou6D-4ofqA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phb | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
PF14262(Cthe_2159) | 5 | GLU A 120ALA A 122GLY A 98SER A 74ASP A 126 | None | 0.98A | 3ou6D-4phbA:undetectable | 3ou6D-4phbA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1p | L-ARABINOSEISOMERASE (Geobacilluskaustophilus) |
PF02610(Arabinose_Isome)PF11762(Arabinose_Iso_C) | 5 | LEU A 403ALA A 314SER A 393LEU A 318TRP A 205 | None | 1.45A | 3ou6D-4r1pA:undetectable | 3ou6D-4r1pA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rya | ABC TRANSPORTERSUBSTRATE BINDINGPROTEIN (SORBITOL) (Agrobacteriumvitis) |
PF01547(SBP_bac_1) | 5 | LEU A 101GLU A 88ALA A 89MET A 82LEU A 123 | None | 1.45A | 3ou6D-4ryaA:undetectable | 3ou6D-4ryaA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvo | MALATE DEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ALA A 252GLY A 129SER A 155MET A 267LEU A 87 | None | 1.26A | 3ou6D-4tvoA:4.5 | 3ou6D-4tvoA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyr | ACETYL-COAACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 377GLU A 198GLY A 354SER A 353LEU A 358 | None | 1.28A | 3ou6D-4wyrA:undetectable | 3ou6D-4wyrA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmv | AMINOPEPTIDASE N (Escherichiacoli) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | TYR A 288ALA A 223SER A 229ASP A 199LEU A 197 | NoneNoneNoneGOL A 915 (-2.9A)None | 1.40A | 3ou6D-4xmvA:undetectable | 3ou6D-4xmvA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zaa | FDC1 (Aspergillusniger) |
PF01977(UbiD) | 5 | GLU A 233ALA A 234TRP A 166GLY A 238LEU A 245 | MN A 603 ( 2.7A)NoneNoneNoneNone | 1.25A | 3ou6D-4zaaA:undetectable | 3ou6D-4zaaA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zdn | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 928GLU A 923ALA A 925GLY A 580LEU A 577 | None | 1.41A | 3ou6D-4zdnA:undetectable | 3ou6D-4zdnA:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqu | CDIA-CT TOXIN,CONSERVED DOMAINPROTEINCDII TOXIN (Yersiniapseudotuberculosis;Salmonellaenterica) |
no annotationPF07262(CdiI) | 5 | ALA B 67GLY A 187SER A 188ASP B 86LEU B 82 | None | 1.45A | 3ou6D-4zquB:undetectable | 3ou6D-4zquB:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a40 | PUTATIVE FLUORIDEION TRANSPORTER CRCB (Bordetellapertussis) |
PF02537(CRCB) | 5 | TYR A 104ALA A 42GLY A 47SER A 112LEU A 79 | None | 1.45A | 3ou6D-5a40A:undetectable | 3ou6D-5a40A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp1 | MYCOCEROSIC ACIDSYNTHASE (Mycolicibacteriumsmegmatis) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 375GLU A 30ALA A 31GLY A 35ASP A 37 | None | 1.42A | 3ou6D-5bp1A:undetectable | 3ou6D-5bp1A:14.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgk | ACTIVE HELICASE (Staphylococcusaureus) |
PF06048(DUF927) | 5 | LEU A 119TYR A 125ALA A 360GLY A 117LEU A 129 | None | 1.34A | 3ou6D-5dgkA:undetectable | 3ou6D-5dgkA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ec0 | ALP7A (Bacillussubtilis) |
no annotation | 5 | TYR A 327GLU A 360ALA A 359GLY A 329LEU A 365 | NoneNoneNoneADP A 403 (-3.6A)None | 1.26A | 3ou6D-5ec0A:undetectable | 3ou6D-5ec0A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eio | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE/N-ACETYL-GAMMA-AMINOADIPYL-PHOSPHATE REDUCTASE (Thermusthermophilus) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | LEU A 75GLU A 18ALA A 15ASP A 96LEU A 97 | NAP A 401 (-4.6A)NoneNAP A 401 (-3.3A)NoneNAP A 401 (-4.9A) | 1.24A | 3ou6D-5eioA:2.9 | 3ou6D-5eioA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h02 | GLYCINE SARCOSINEN-METHYLTRANSFERASE (Methanohalophilusportucalensis) |
PF13649(Methyltransf_25) | 5 | ALA A 67GLY A 89SER A 90MET A 93ASP A 114 | SAH A 301 (-3.9A)SAH A 301 (-3.4A)SAH A 301 ( 4.9A)SAH A 301 (-3.9A)SAH A 301 (-3.7A) | 0.48A | 3ou6D-5h02A:16.8 | 3ou6D-5h02A:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb1 | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF03177(Nucleoporin_C) | 5 | TYR A 905GLU A 867ALA A 865SER A 907LEU A 875 | None | 1.20A | 3ou6D-5hb1A:undetectable | 3ou6D-5hb1A:12.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hfi | UNCHARACTERIZEDPROTEIN, CYTOSOLICDISULFIDE REDUCTASEDSBM (Pseudomonasaeruginosa) |
PF01323(DSBA) | 5 | TYR A 8GLU A 29ALA A 27LEU A 207TRP A 203 | TYR A 8 ( 1.3A)GLU A 29 ( 0.6A)ALA A 27 ( 0.0A)LEU A 207 ( 0.6A)TRP A 203 ( 0.5A) | 1.41A | 3ou6D-5hfiA:undetectable | 3ou6D-5hfiA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hu6 | HAPTOGLOBIN-HEMOGLOBIN RECEPTOR (Trypanosomabrucei) |
no annotation | 5 | TYR D 66ALA D 155GLY D 159SER D 161LEU D 239 | None | 1.45A | 3ou6D-5hu6D:undetectable | 3ou6D-5hu6D:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvk | UNCHARACTERIZEDPROTEIN (Bacteroidescellulosilyticus) |
no annotation | 5 | LEU A 260TYR A 259TRP A 363GLY A 304LEU A 300 | None | 1.45A | 3ou6D-5jvkA:undetectable | 3ou6D-5jvkA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqi | CATALASE-PEROXIDASE (Burkholderiapseudomallei) |
PF00141(peroxidase) | 5 | LEU A 635GLU A 717ALA A 716ASP A 703LEU A 668 | None | 1.32A | 3ou6D-5kqiA:undetectable | 3ou6D-5kqiA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks1 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Vibriovulnificus) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | TYR A 232ALA A 324TRP A 237ASP A 361LEU A 364 | None | 1.44A | 3ou6D-5ks1A:undetectable | 3ou6D-5ks1A:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ocr | KAPPA-CARRAGEENASE (Zobelliagalactanivorans) |
no annotation | 5 | LEU A 208GLU A 241ALA A 243ASP A 182LEU A 183 | None | 1.31A | 3ou6D-5ocrA:undetectable | 3ou6D-5ocrA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t9x | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) |
no annotation | 5 | GLU A 193ALA A 194TRP A 179GLY A 196SER A 172 | IMD A 402 (-3.6A)NoneIMD A 402 (-3.5A)NoneNone | 1.44A | 3ou6D-5t9xA:undetectable | 3ou6D-5t9xA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8s | DNA REPLICATIONLICENSING FACTORMCM4 (Saccharomycescerevisiae) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 5 | LEU 4 623GLU 4 647GLY 4 619SER 4 618LEU 4 601 | None | 1.41A | 3ou6D-5u8s4:undetectable | 3ou6D-5u8s4:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uc0 | UNCHARACTERIZEDPROTEIN COG5400 (Brucellaabortus) |
PF06577(DUF1134) | 5 | LEU A 99TYR A 100GLU A 45GLY A 77LEU A 130 | None | 1.44A | 3ou6D-5uc0A:undetectable | 3ou6D-5uc0A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5voc | ENVELOPEGLYCOPROTEIN H (Humanbetaherpesvirus5) |
PF02489(Herpes_glycop_H)PF17488(Herpes_glycoH_C) | 5 | ALA A 351GLY A 185SER A 184ASP A 146LEU A 309 | None | 1.22A | 3ou6D-5vocA:undetectable | 3ou6D-5vocA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wql | TAIL-SPECIFICPROTEASE (Escherichiacoli) |
no annotation | 5 | TYR C 438ALA C 467GLY C 465SER C 561ASP C 463 | None | 1.43A | 3ou6D-5wqlC:undetectable | 3ou6D-5wqlC:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wrr | PSEUDOKINASE FAM20A (Homo sapiens) |
PF06702(Fam20C) | 5 | LEU A 486GLU A 326GLY A 338SER A 339LEU A 336 | None | 1.32A | 3ou6D-5wrrA:undetectable | 3ou6D-5wrrA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgl | SOLUBLEACETYLCHOLINERECEPTOR (Aplysiacalifornica) |
no annotation | 5 | TYR A 186GLY A 149SER A 148ASP A 153LEU A 154 | None | 1.40A | 3ou6D-5xglA:undetectable | 3ou6D-5xglA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn6 | OS07G0580900 PROTEINOS02G0668100 PROTEIN (Oryza sativa;Oryza sativa) |
PF00348(polyprenyl_synt)PF00348(polyprenyl_synt) | 5 | GLU C 150ALA C 152GLY C 156SER C 157ASP A 116 | None | 1.31A | 3ou6D-5xn6C:undetectable | 3ou6D-5xn6C:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | ALA B 407GLY B 238SER B 239ASP B 48LEU B 49 | None | 1.22A | 3ou6D-5xogB:undetectable | 3ou6D-5xogB:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6arx | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | TYR A 583GLY A 481SER A 482LEU A 479TRP A 633 | None | 1.42A | 3ou6D-6arxA:undetectable | 3ou6D-6arxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9m | N-ALPHA-ACETYLTRANSFERASE 10 (Homo sapiens) |
no annotation | 5 | LEU B 75GLU B 46ALA B 45MET B 14LEU B 86 | None | 1.31A | 3ou6D-6c9mB:undetectable | 3ou6D-6c9mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | PROBABLEMEMBRANE-BOUNDHYDROGENASE SUBUNITMBHJMBH13 NADHDEHYDROGENASESUBUNIT (Pyrococcusfuriosus;Pyrococcusfuriosus) |
no annotationno annotation | 5 | TYR M 125GLU M 211ALA M 215GLY J 61SER J 62 | None | 1.44A | 3ou6D-6cfwM:undetectable | 3ou6D-6cfwM:undetectable |