SIMILAR PATTERNS OF AMINO ACIDS FOR 3OU6_C_SAMC300_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dwa MYROSINASE MA1

(Sinapis alba) 		PF00232
(Glyco_hydro_1) 		3 TYR M 463
GLY M  67
ASP M  65
 None
 0.64A 3ou6C-1dwaM:
undetectable		 3ou6C-1dwaM:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5n INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		3 TYR A  47
GLY A 102
ASP A 112
 None
 0.71A 3ou6C-1f5nA:
undetectable		 3ou6C-1f5nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ftg APOFLAVODOXIN

(Nostoc sp. PCC
7119) 		PF00258
(Flavodoxin_1) 		3 TYR A  94
GLY A  89
ASP A 144
 None
 0.73A 3ou6C-1ftgA:
undetectable		 3ou6C-1ftgA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcd HISACTOPHILIN

(Dictyostelium
discoideum) 		PF06268
(Fascin) 		3 TYR A  62
GLY A  56
ASP A  57
 None
 0.73A 3ou6C-1hcdA:
undetectable		 3ou6C-1hcdA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 TYR A 107
GLY A 113
ASP A 128
 None
 0.71A 3ou6C-1kcwA:
undetectable		 3ou6C-1kcwA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE

(Lactococcus
lactis) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N) 		3 TYR A 477
GLY A 551
ASP A 549
 None
 0.73A 3ou6C-1lnsA:
undetectable		 3ou6C-1lnsA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0w GLUTATHIONE
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		3 TYR A 446
GLY A 444
ASP A 130
 None
 0.69A 3ou6C-1m0wA:
undetectable		 3ou6C-1m0wA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7j PHENYLETHANOLAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  35
GLY A  81
ASP A 101
 SAH  A2002 ( 4.4A)
SAH  A2002 (-3.0A)
SAH  A2002 (-3.1A)
 0.37A 3ou6C-1n7jA:
17.0		 3ou6C-1n7jA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1okg POSSIBLE
3-MERCAPTOPYRUVATE
SULFURTRANSFERASE

(Leishmania
major) 		PF00581
(Rhodanese)
PF09122
(DUF1930) 		3 TYR A 193
GLY A 312
ASP A 313
 None
 0.64A 3ou6C-1okgA:
undetectable		 3ou6C-1okgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2e EXOCELLOBIOHYDROLASE
I

(Trichoderma
reesei) 		PF00840
(Glyco_hydro_7) 		3 TYR A 158
GLY A 154
ASP A 152
 None
 0.62A 3ou6C-1q2eA:
undetectable		 3ou6C-1q2eA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN

(Rasamsonia
emersonii) 		PF00840
(Glyco_hydro_7) 		3 TYR A 155
GLY A 151
ASP A 149
 None
 0.59A 3ou6C-1q9hA:
undetectable		 3ou6C-1q9hA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 TYR A  36
GLY A  48
ASP A  17
 None
CA  A 698 (-4.0A)
None
 0.71A 3ou6C-1qhoA:
undetectable		 3ou6C-1qhoA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qmo MANNOSE BINDING
LECTIN, FRIL
MANNOSE BINDING
LECTIN, FRIL

(Lablab
purpureus;
Lablab
purpureus) 		PF00139
(Lectin_legB)
PF00139
(Lectin_legB) 		3 TYR E 147
GLY A 104
ASP A  86
 None
MAN  A 302 (-3.7A)
MAN  A 302 (-3.2A)
 0.52A 3ou6C-1qmoE:
undetectable		 3ou6C-1qmoE:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sdd COAGULATION FACTOR V

(Bos taurus) 		PF07732
(Cu-oxidase_3) 		3 TYR A  91
GLY A  97
ASP A 112
 None
None
CA  A2184 (-2.5A)
 0.70A 3ou6C-1sddA:
undetectable		 3ou6C-1sddA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqh CARBOXYLESTERASE
PRECURSOR

(Geobacillus
stearothermophilus) 		PF12146
(Hydrolase_4) 		3 TYR A 134
GLY A  27
ASP A  31
 None
4PA  A 701 (-3.5A)
4PA  A 701 (-4.1A)
 0.58A 3ou6C-1tqhA:
2.4		 3ou6C-1tqhA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 2

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 TYR B 215
GLY B 300
ASP B 305
 None
 0.69A 3ou6C-1tqyB:
undetectable		 3ou6C-1tqyB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdt ELONGATION FACTOR G
HOMOLOG

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		3 TYR A 626
GLY A 429
ASP A  86
 None
 0.67A 3ou6C-1wdtA:
undetectable		 3ou6C-1wdtA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzn SAM-DEPENDENT
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF13649
(Methyltransf_25) 		3 TYR A  12
GLY A  51
ASP A  70
 SAH  A1001 (-4.9A)
SAH  A1001 (-3.1A)
SAH  A1001 (-2.7A)
 0.19A 3ou6C-1wznA:
19.1		 3ou6C-1wznA:
28.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3v CELLULASE

(Phanerochaete
chrysosporium) 		PF00840
(Glyco_hydro_7) 		3 TYR A 155
GLY A 151
ASP A 149
 None
 0.64A 3ou6C-1z3vA:
undetectable		 3ou6C-1z3vA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a14 INDOLETHYLAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  20
GLY A  65
ASP A  85
 SAH  A4001 (-4.2A)
SAH  A4001 (-3.0A)
SAH  A4001 (-2.7A)
 0.27A 3ou6C-2a14A:
17.1		 3ou6C-2a14A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avn UBIQUINONE/MENAQUINO
NE BIOSYNTHESIS
METHYLTRANSFERASE-RE
LATED PROTEIN

(Thermotoga
maritima) 		PF08241
(Methyltransf_11) 		3 TYR A  16
GLY A  52
ASP A  71
 SAI  A1300 (-4.9A)
SAI  A1300 (-3.5A)
SAI  A1300 (-2.9A)
 0.20A 3ou6C-2avnA:
18.8		 3ou6C-2avnA:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bq8 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5

(Homo sapiens) 		PF00149
(Metallophos) 		3 TYR X 185
GLY X  88
ASP X  50
 None
None
FE2  X1306 ( 2.8A)
 0.72A 3ou6C-2bq8X:
undetectable		 3ou6C-2bq8X:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c49 SUGAR KINASE MJ0406

(Methanocaldococcus
jannaschii) 		PF00294
(PfkB) 		3 TYR A 121
GLY A 139
ASP A 164
 None
None
ADN  A1301 (-2.9A)
 0.53A 3ou6C-2c49A:
2.7		 3ou6C-2c49A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ev2 HYPOTHETICAL PROTEIN
RV1264/MT1302

(Mycobacterium
tuberculosis) 		PF16701
(Ad_Cy_reg) 		3 TYR A  66
GLY A  64
ASP A  63
 None
 0.72A 3ou6C-2ev2A:
undetectable		 3ou6C-2ev2A:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewy BETA-SECRETASE 2

(Homo sapiens) 		PF00026
(Asp) 		3 TYR A  31
GLY A  24
ASP A  25
 None
 0.71A 3ou6C-2ewyA:
undetectable		 3ou6C-2ewyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i62 NICOTINAMIDE
N-METHYLTRANSFERASE

(Mus musculus) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  21
GLY A  66
ASP A  86
 SAH  A4001 (-4.5A)
SAH  A4001 (-3.2A)
SAH  A4001 (-2.9A)
 0.41A 3ou6C-2i62A:
17.6		 3ou6C-2i62A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icw T-CELL RECEPTOR BETA
CHAIN V

(Mus musculus) 		PF07686
(V-set) 		3 TYR J  48
GLY J  58
ASP J  59
 None
 0.60A 3ou6C-2icwJ:
undetectable		 3ou6C-2icwJ:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iip NICOTINAMIDE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  20
GLY A  65
ASP A  85
 SAH  A4001 (-4.6A)
SAH  A4001 (-3.0A)
SAH  A4001 (-2.6A)
 0.28A 3ou6C-2iipA:
17.2		 3ou6C-2iipA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kmg KLCA

(Bordetella
pertussis) 		PF03230
(Antirestrict) 		3 TYR A  25
GLY A  62
ASP A  61
 None
 0.68A 3ou6C-2kmgA:
undetectable		 3ou6C-2kmgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1y BISPECIFIC
ALPHA/BETA TCR

(Mus musculus) 		PF07686
(V-set) 		3 TYR A  48
GLY A  58
ASP A  59
 None
 0.56A 3ou6C-2p1yA:
undetectable		 3ou6C-2p1yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe6 UNCHARACTERIZED
PROTEIN TFU_2867

(Thermobifida
fusca) 		PF04672
(Methyltransf_19) 		3 TYR A  26
GLY A  86
ASP A 110
 SAM  A 400 ( 3.8A)
SAM  A 400 ( 3.2A)
SAM  A 400 (-2.7A)
 0.72A 3ou6C-2qe6A:
13.3		 3ou6C-2qe6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhp THROMBOSPONDIN-2

(Homo sapiens) 		PF02412
(TSP_3)
PF05735
(TSP_C)
PF07645
(EGF_CA)
PF12947
(EGF_3) 		3 TYR A 819
GLY A 805
ASP A 802
 None
None
CA  A  20 (-3.1A)
 0.61A 3ou6C-2rhpA:
undetectable		 3ou6C-2rhpA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 TYR A  91
GLY A  83
ASP A  84
 None
 0.68A 3ou6C-2v6oA:
undetectable		 3ou6C-2v6oA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w45 ALKALINE EXONUCLEASE

(Human
gammaherpesvirus
4) 		PF01771
(Herpes_alk_exo) 		3 TYR A 362
GLY A 366
ASP A 367
 None
 0.60A 3ou6C-2w45A:
undetectable		 3ou6C-2w45A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xj6 ASCORBATE PEROXIDASE

(Glycine max) 		PF00141
(peroxidase) 		3 TYR A  97
GLY A  58
ASP A 121
 None
 0.71A 3ou6C-2xj6A:
undetectable		 3ou6C-2xj6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding)
PF15447
(NTS) 		3 TYR A 274
GLY A 293
ASP A 277
 None
 0.70A 3ou6C-2xu0A:
undetectable		 3ou6C-2xu0A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yok EXOGLUCANASE 1

(Trichoderma
harzianum) 		PF00840
(Glyco_hydro_7) 		3 TYR A 171
GLY A 167
ASP A 165
 None
 0.59A 3ou6C-2yokA:
undetectable		 3ou6C-2yokA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyl 4-HYDROXYPHENYLACETA
TE-3-HYDROXYLASE

(Thermus
thermophilus) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 TYR A 456
GLY A 356
ASP A 354
 None
 0.55A 3ou6C-2yylA:
undetectable		 3ou6C-2yylA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bmw CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		3 TYR A  39
GLY A  51
ASP A  23
 None
CA  A 699 (-3.9A)
None
 0.71A 3ou6C-3bmwA:
undetectable		 3ou6C-3bmwA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c60 TCR YAE62 BETA CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  46
GLY B  56
ASP B  57
 None
 0.57A 3ou6C-3c60B:
undetectable		 3ou6C-3c60B:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6l TCR 2W20 BETA CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  46
GLY B  56
ASP B  57
 None
 0.53A 3ou6C-3c6lB:
undetectable		 3ou6C-3c6lB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis) 		PF13354
(Beta-lactamase2) 		3 TYR A 150
GLY A 146
ASP A 170
 None
 0.58A 3ou6C-3cjmA:
undetectable		 3ou6C-3cjmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e23 UNCHARACTERIZED
PROTEIN RPA2492

(Rhodopseudomonas
palustris) 		PF08241
(Methyltransf_11) 		3 TYR A  24
GLY A  53
ASP A  72
 SAM  A 221 (-4.7A)
SAM  A 221 (-3.2A)
SAM  A 221 (-2.8A)
 0.31A 3ou6C-3e23A:
18.8		 3ou6C-3e23A:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5t TRANS-ACONITATE
3-METHYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF13847
(Methyltransf_31) 		3 TYR A  14
GLY A  46
ASP A  68
 SAH  A 308 ( 4.6A)
SAH  A 308 (-3.6A)
SAH  A 308 (-2.6A)
 0.26A 3ou6C-3g5tA:
12.8		 3ou6C-3g5tA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 TYR A 148
GLY A 218
ASP A 216
 None
 0.69A 3ou6C-3gwjA:
undetectable		 3ou6C-3gwjA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyr PHENOXAZINONE
SYNTHASE

(Streptomyces
antibioticus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 TYR A 304
GLY A 302
ASP A 417
 None
 0.64A 3ou6C-3gyrA:
undetectable		 3ou6C-3gyrA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2x TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 22

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 TYR A 242
GLY A  92
ASP A 219
 None
 0.64A 3ou6C-3h2xA:
undetectable		 3ou6C-3h2xA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbu SECRETED PROTEASE C

(Dickeya
chrysanthemi) 		PF00353
(HemolysinCabind)
PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		3 TYR P  24
GLY P 391
ASP P 395
 None
 0.67A 3ou6C-3hbuP:
undetectable		 3ou6C-3hbuP:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ho8 PYRUVATE CARBOXYLASE

(Staphylococcus
aureus) 		PF00289
(Biotin_carb_N)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 TYR A 862
GLY A 745
ASP A 742
 None
 0.71A 3ou6C-3ho8A:
3.0		 3ou6C-3ho8A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN

(Burkholderia
mallei) 		PF13458
(Peripla_BP_6) 		3 TYR A  40
GLY A 228
ASP A 258
 AAE  A 501 ( 4.0A)
EDO  A   8 ( 4.0A)
EDO  A   8 (-3.3A)
 0.70A 3ou6C-3i09A:
2.4		 3ou6C-3i09A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o7q L-FUCOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		3 TYR A 382
GLY A 245
ASP A 241
 None
 0.69A 3ou6C-3o7qA:
undetectable		 3ou6C-3o7qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oa2 WBPB

(Pseudomonas
aeruginosa) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 TYR A 126
GLY A 280
ASP A 283
 None
 0.72A 3ou6C-3oa2A:
3.6		 3ou6C-3oa2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orw PHOSPHOTRIESTERASE

(Geobacillus
kaustophilus) 		PF02126
(PTE) 		3 TYR A 100
GLY A 104
ASP A  73
 None
 0.67A 3ou6C-3orwA:
undetectable		 3ou6C-3orwA:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ou6 SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
luridus) 		PF13649
(Methyltransf_25) 		3 TYR A  22
GLY A  56
ASP A  75
 SAM  A 300 (-4.4A)
SAM  A 300 (-3.1A)
SAM  A 300 (-2.8A)
 0.04A 3ou6C-3ou6A:
38.1		 3ou6C-3ou6A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvl MYOSIN VIIA ISOFORM
1

(Mus musculus) 		PF00784
(MyTH4) 		3 TYR A1083
GLY A1033
ASP A1031
 None
 0.63A 3ou6C-3pvlA:
undetectable		 3ou6C-3pvlA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q06 CELLULAR TUMOR
ANTIGEN P53

(Homo sapiens) 		PF00870
(P53)
PF07710
(P53_tetramer) 		3 TYR A 327
GLY A 325
ASP A 324
 None
 0.64A 3ou6C-3q06A:
undetectable		 3ou6C-3q06A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)

(Mus musculus) 		PF07686
(V-set) 		3 TYR C 181
GLY C 191
ASP C 192
 None
 0.56A 3ou6C-3tf7C:
undetectable		 3ou6C-3tf7C:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpu 42F3 BETA

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  48
GLY B  58
ASP B  59
 None
 0.57A 3ou6C-3tpuB:
undetectable		 3ou6C-3tpuB:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B

(Bacillus
subtilis) 		PF12705
(PDDEXK_1) 		3 TYR B 211
GLY B 209
ASP B 208
 None
 0.73A 3ou6C-3u44B:
undetectable		 3ou6C-3u44B:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4t TPR
REPEAT-CONTAINING
PROTEIN

(Cytophaga
hutchinsonii) 		PF07719
(TPR_2) 		3 TYR A 455
GLY A 421
ASP A 415
 None
 0.58A 3ou6C-3u4tA:
undetectable		 3ou6C-3u4tA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 TYR A 138
GLY A 234
ASP A 167
 None
 0.67A 3ou6C-3v9eA:
undetectable		 3ou6C-3v9eA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vil BETA-GLUCOSIDASE

(Neotermes
koshunensis) 		PF00232
(Glyco_hydro_1) 		3 TYR A 128
GLY A 124
ASP A 123
 None
 0.65A 3ou6C-3vilA:
undetectable		 3ou6C-3vilA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vm7 ALPHA-AMYLASE

(Malbranchea
cinnamomea) 		PF00128
(Alpha-amylase)
PF09260
(DUF1966) 		3 TYR A 361
GLY A  54
ASP A  52
 None
 0.67A 3ou6C-3vm7A:
undetectable		 3ou6C-3vm7A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0w T36-5 TCR BETA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR E  48
GLY E  58
ASP E  59
 None
 0.59A 3ou6C-3w0wE:
undetectable		 3ou6C-3w0wE:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apq MOUSE NKT TCR
AUTOREACTIVE-VBETA6,
HUMAN NKT TCR
AUTOREACTIVE-VBETA6

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR D  48
GLY D  58
ASP D  59
 None
 0.44A 3ou6C-4apqD:
undetectable		 3ou6C-4apqD:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF04153
(NOT2_3_5) 		3 TYR B 187
GLY B 161
ASP B 160
 None
 0.61A 3ou6C-4by6B:
undetectable		 3ou6C-4by6B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csi CELLULASE

(Humicola grisea) 		PF00840
(Glyco_hydro_7) 		3 TYR A 159
GLY A 155
ASP A 153
 None
 0.59A 3ou6C-4csiA:
undetectable		 3ou6C-4csiA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1l ANI2.3 TCR B CHAIN

(Escherichia
coli) 		PF07686
(V-set) 		3 TYR H  46
GLY H  56
ASP H  57
 None
 0.51A 3ou6C-4h1lH:
undetectable		 3ou6C-4h1lH:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4haq GH7 FAMILY PROTEIN

(Limnoria
quadripunctata) 		PF00840
(Glyco_hydro_7) 		3 TYR A 179
GLY A 175
ASP A 173
 None
 0.55A 3ou6C-4haqA:
undetectable		 3ou6C-4haqA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kfz LMO-2

(Homo sapiens) 		PF00412
(LIM) 		3 TYR A  84
GLY A  89
ASP A  91
 None
 0.69A 3ou6C-4kfzA:
undetectable		 3ou6C-4kfzA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 ARYLPHORIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 TYR B 147
GLY B 217
ASP B 215
 None
 0.68A 3ou6C-4l37B:
undetectable		 3ou6C-4l37B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 TYR A 144
GLY A 214
ASP A 212
 None
SCN  A 711 ( 4.4A)
None
 0.73A 3ou6C-4l37A:
undetectable		 3ou6C-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsl PYRUVATE CARBOXYLASE

(Listeria
monocytogenes) 		no annotation 3 TYR H 828
GLY H 714
ASP H 711
 None
 0.71A 3ou6C-4qslH:
undetectable		 3ou6C-4qslH:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtu PUTATIVE
METHYLTRANSFERASE
BUD23

(Saccharomyces
cerevisiae) 		PF08241
(Methyltransf_11) 		3 TYR B  22
GLY B  57
ASP B  77
 SAM  B 301 (-4.6A)
SAM  B 301 (-3.3A)
SAM  B 301 (-2.6A)
 0.62A 3ou6C-4qtuB:
15.7		 3ou6C-4qtuB:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1n 3-HYDROXYBUTYRYL-COA
DEHYDROGENASE

(Clostridium
butyricum) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		3 TYR A 263
GLY A 276
ASP A 231
 None
 0.65A 3ou6C-4r1nA:
5.8		 3ou6C-4r1nA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT

(Aquincola
tertiaricarbonis) 		PF01642
(MM_CoA_mutase) 		3 TYR A 486
GLY A  94
ASP A  98
 None
 0.70A 3ou6C-4r3uA:
undetectable		 3ou6C-4r3uA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v15 D-THREONINE ALDOLASE

(Achromobacter
xylosoxidans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		3 TYR A 187
GLY A 231
ASP A 239
 PLP  A1380 (-3.5A)
None
None
 0.59A 3ou6C-4v15A:
undetectable		 3ou6C-4v15A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v20 CELLOBIOHYDROLASE

(Aspergillus
fumigatus) 		PF00840
(Glyco_hydro_7) 		3 TYR A 158
GLY A 154
ASP A 152
 None
 0.56A 3ou6C-4v20A:
undetectable		 3ou6C-4v20A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeb GLUCANASE

(Talaromyces
funiculosus) 		PF00840
(Glyco_hydro_7) 		3 TYR A 155
GLY A 151
ASP A 149
 None
 0.60A 3ou6C-4xebA:
undetectable		 3ou6C-4xebA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xtk CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Thermotoga
maritima) 		PF01867
(Cas_Cas1) 		3 TYR A  93
GLY A 211
ASP A 226
 None
 0.67A 3ou6C-4xtkA:
undetectable		 3ou6C-4xtkA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bz4 BETA-KETOTHIOLASE

(Mycolicibacterium
smegmatis) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		3 TYR A  59
GLY A 144
ASP A 143
 None
 0.64A 3ou6C-5bz4A:
undetectable		 3ou6C-5bz4A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9d A6-TCR VBETA

(Homo sapiens) 		PF07686
(V-set) 		3 TYR E  48
GLY E  58
ASP E  59
 None
 0.59A 3ou6C-5e9dE:
undetectable		 3ou6C-5e9dE:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5euo PF6 TCR BETA CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR F  46
GLY F  56
ASP F  57
 None
 0.57A 3ou6C-5euoF:
undetectable		 3ou6C-5euoF:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fav CHOLINE
TRIMETHYLAMINE-LYASE

(Desulfovibrio
alaskensis) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 TYR A 584
GLY A 220
ASP A 222
 None
 0.65A 3ou6C-5favA:
undetectable		 3ou6C-5favA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 TYR B1217
GLY B1164
ASP B1190
 None
 0.66A 3ou6C-5ip9B:
undetectable		 3ou6C-5ip9B:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd9 SPORE COAT PROTEIN H

(Bacillus cereus) 		PF08757
(CotH) 		3 TYR A 119
GLY A 117
ASP A 322
 None
 0.71A 3ou6C-5jd9A:
undetectable		 3ou6C-5jd9A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k6u PROTEIN SIDEKICK-1

(Mus musculus) 		PF07679
(I-set)
PF13927
(Ig_3) 		3 TYR A 374
GLY A  78
ASP A 325
 None
 0.68A 3ou6C-5k6uA:
undetectable		 3ou6C-5k6uA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k6w PROTEIN SIDEKICK-1

(Mus musculus) 		PF07679
(I-set)
PF13927
(Ig_3) 		3 TYR A 374
GLY A  78
ASP A 325
 None
 0.72A 3ou6C-5k6wA:
undetectable		 3ou6C-5k6wA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkm DNA REPAIR PROTEIN
RADA

(Streptococcus
pneumoniae) 		PF13481
(AAA_25)
PF13541
(ChlI) 		3 TYR A 235
GLY A  95
ASP A  96
 None
 0.59A 3ou6C-5lkmA:
3.0		 3ou6C-5lkmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mch CELLOBIOHYDROLASE
CHBI

(Daphnia pulex) 		PF00840
(Glyco_hydro_7) 		3 TYR A 182
GLY A 178
ASP A 176
 None
 0.64A 3ou6C-5mchA:
undetectable		 3ou6C-5mchA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o5d GLUCANASE

(Trichoderma
atroviride) 		no annotation 3 TYR A 158
GLY A 154
ASP A 152
 None
 0.59A 3ou6C-5o5dA:
undetectable		 3ou6C-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oes GLUTATHIONE
SYNTHETASE

(Solanum
tuberosum) 		no annotation 3 TYR A 438
GLY A 436
ASP A 139
 None
None
MG  A 504 (-3.7A)
 0.71A 3ou6C-5oesA:
undetectable		 3ou6C-5oesA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olj DIPEPTIDYL PEPTIDASE
IV

(Porphyromonas
gingivalis) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 TYR A  69
GLY A  51
ASP A  50
 None
 0.65A 3ou6C-5oljA:
undetectable		 3ou6C-5oljA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8q INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR

(Homo sapiens) 		no annotation 3 TYR A 101
GLY A  99
ASP A  97
 None
 0.68A 3ou6C-5u8qA:
undetectable		 3ou6C-5u8qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD

(Escherichia
coli) 		PF02470
(MlaD) 		3 TYR A  43
GLY A 131
ASP A 130
 None
 0.68A 3ou6C-5uw8A:
undetectable		 3ou6C-5uw8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyw PYRUVATE CARBOXYLASE

(Lactococcus
lactis) 		PF00289
(Biotin_carb_N)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 TYR A 821
GLY A 707
ASP A 704
 None
 0.69A 3ou6C-5vywA:
3.0		 3ou6C-5vywA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w11 GLUCANASE

(Thermothelomyces
thermophila) 		no annotation 3 TYR A 159
GLY A 155
ASP A 153
 None
 0.65A 3ou6C-5w11A:
undetectable		 3ou6C-5w11A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5y UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		PF03739
(YjgP_YjgQ)
PF03739
(YjgP_YjgQ) 		3 TYR F 216
GLY G 181
ASP G 177
 None
 0.67A 3ou6C-5x5yF:
undetectable		 3ou6C-5x5yF:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 3 TYR A 568
GLY A 624
ASP A 625
 None
 0.69A 3ou6C-5xpgA:
undetectable		 3ou6C-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dk2 -

(-) 		no annotation 3 TYR A 254
GLY A 318
ASP A 319
 None
 0.68A 3ou6C-6dk2A:
undetectable		 3ou6C-6dk2A:
undetectable