SIMILAR PATTERNS OF AMINO ACIDS FOR 3OU6_B_SAMB300_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT

(Klebsiella
pneumoniae) 		PF02286
(Dehydratase_LU) 		3 TYR A 371
ASP A 381
ASP A 387
 None
 0.85A 3ou6B-1iwpA:
undetectable		 3ou6B-1iwpA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		3 TYR A  41
ASP A  35
ASP A 251
 None
 0.94A 3ou6B-1kb0A:
undetectable		 3ou6B-1kb0A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE

(Lactococcus
lactis) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N) 		3 TYR A 380
ASP A 468
ASP A 647
 None
 0.94A 3ou6B-1lnsA:
undetectable		 3ou6B-1lnsA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7j PHENYLETHANOLAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  35
ASP A 101
ASP A 158
 SAH  A2002 ( 4.4A)
SAH  A2002 (-3.1A)
SAH  A2002 (-3.6A)
 0.42A 3ou6B-1n7jA:
17.0		 3ou6B-1n7jA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odf HYPOTHETICAL 33.3
KDA PROTEIN IN
ADE3-SER2 INTERGENIC
REGION

(Saccharomyces
cerevisiae) 		no annotation 3 TYR A  67
ASP A  72
ASP A 132
 None
 0.94A 3ou6B-1odfA:
undetectable		 3ou6B-1odfA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		3 TYR A 794
ASP A 844
ASP A 847
 None
 0.89A 3ou6B-1ofeA:
undetectable		 3ou6B-1ofeA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1orr CDP-TYVELOSE-2-EPIME
RASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		3 TYR A 129
ASP A 173
ASP A 178
 None
 0.87A 3ou6B-1orrA:
4.7		 3ou6B-1orrA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT
2-OXOISOVALERATE
DEHYDROGENASE
BETA-SUBUNIT

(Pseudomonas
putida;
Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 TYR A 394
ASP B 212
ASP B 260
 None
 0.86A 3ou6B-1qs0A:
undetectable		 3ou6B-1qs0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfc PROTEIN
(SYNAPTOBREVIN 2)
PROTEIN (SYNTAXIN
1A)

(Rattus
norvegicus;
Rattus
norvegicus) 		PF00957
(Synaptobrevin)
PF00804
(Syntaxin)
PF05739
(SNARE) 		3 TYR B 235
ASP A  64
ASP A  57
 None
 0.87A 3ou6B-1sfcB:
undetectable		 3ou6B-1sfcB:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9h PROBABLE GTPASE ENGC

(Bacillus
subtilis) 		PF03193
(RsgA_GTPase)
PF16745
(RsgA_N) 		3 TYR A 142
ASP A  98
ASP A 282
 ACT  A 416 (-3.7A)
None
None
 0.83A 3ou6B-1t9hA:
2.2		 3ou6B-1t9hA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u7k GAG POLYPROTEIN

(Murine leukemia
virus) 		PF02093
(Gag_p30) 		3 TYR A 106
ASP A  54
ASP A  19
 None
 0.86A 3ou6B-1u7kA:
undetectable		 3ou6B-1u7kA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uc4 DIOL DEHYDRASE ALPHA
SUBUNIT

(Klebsiella
oxytoca) 		PF02286
(Dehydratase_LU) 		3 TYR A 370
ASP A 380
ASP A 386
 None
 0.93A 3ou6B-1uc4A:
undetectable		 3ou6B-1uc4A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur4 GALACTANASE

(Bacillus
licheniformis) 		PF07745
(Glyco_hydro_53) 		3 TYR A 142
ASP A 113
ASP A  75
 None
 0.83A 3ou6B-1ur4A:
undetectable		 3ou6B-1ur4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6m GALACTOSE-BINDING
LECTIN

(Arachis
hypogaea) 		PF00139
(Lectin_legB) 		3 TYR A 130
ASP A  83
ASP A  80
 None
 0.91A 3ou6B-1v6mA:
undetectable		 3ou6B-1v6mA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wky ENDO-BETA-1,4-MANNAN
ASE

(Bacillus sp.
JAMB-602) 		PF00150
(Cellulase) 		3 TYR A 124
ASP A  88
ASP A  95
 None
 0.79A 3ou6B-1wkyA:
undetectable		 3ou6B-1wkyA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wxj TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Thermus
thermophilus) 		PF00290
(Trp_syntA) 		3 TYR A  52
ASP A 127
ASP A 133
 None
 0.90A 3ou6B-1wxjA:
undetectable		 3ou6B-1wxjA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzn SAM-DEPENDENT
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF13649
(Methyltransf_25) 		3 TYR A  12
ASP A  70
ASP A  96
 SAH  A1001 (-4.9A)
SAH  A1001 (-2.7A)
SAH  A1001 (-3.3A)
 0.41A 3ou6B-1wznA:
17.7		 3ou6B-1wznA:
28.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfj CONSERVED
HYPOTHETICAL PROTEIN

(Caulobacter
vibrioides) 		PF02578
(Cu-oxidase_4) 		3 TYR A  74
ASP A  96
ASP A 139
 None
 0.91A 3ou6B-1xfjA:
undetectable		 3ou6B-1xfjA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzy HYPOTHETICAL PROTEIN
HI1011

(Haemophilus
influenzae) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		3 TYR A 190
ASP A 156
ASP A 148
 None
 0.89A 3ou6B-1yzyA:
undetectable		 3ou6B-1yzyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a14 INDOLETHYLAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  20
ASP A  85
ASP A 142
 SAH  A4001 (-4.2A)
SAH  A4001 (-2.7A)
SAH  A4001 (-3.7A)
 0.31A 3ou6B-2a14A:
17.0		 3ou6B-2a14A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN

(Torpedo
marmorata;
Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb)
PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		3 TYR E 104
ASP A  99
ASP A  97
 None
 0.78A 3ou6B-2bg9E:
undetectable		 3ou6B-2bg9E:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg9 CO-CHAPERONE PROTEIN
SBA1

(Saccharomyces
cerevisiae) 		no annotation 3 TYR X  95
ASP X  20
ASP X 122
 None
 0.75A 3ou6B-2cg9X:
undetectable		 3ou6B-2cg9X:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csu 457AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig) 		3 TYR A  40
ASP A  66
ASP A   3
 None
 0.91A 3ou6B-2csuA:
4.7		 3ou6B-2csuA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 TYR A 574
ASP A 711
ASP A 298
 None
 0.75A 3ou6B-2e7zA:
undetectable		 3ou6B-2e7zA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2etv IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF01497
(Peripla_BP_2) 		3 TYR A 333
ASP A 315
ASP A 313
 None
None
EDO  A   5 (-3.9A)
 0.94A 3ou6B-2etvA:
undetectable		 3ou6B-2etvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0t CONSERVED
HYPOTHETICAL PROTEIN

(Thermotoga
maritima) 		PF07755
(DUF1611)
PF17396
(DUF1611_N) 		3 TYR A 249
ASP A 166
ASP A 274
 None
 0.78A 3ou6B-2g0tA:
2.8		 3ou6B-2g0tA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf2 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Homo sapiens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		3 TYR A 198
ASP A 156
ASP A 136
 None
 0.85A 3ou6B-2gf2A:
4.3		 3ou6B-2gf2A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i62 NICOTINAMIDE
N-METHYLTRANSFERASE

(Mus musculus) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  21
ASP A  86
ASP A 143
 SAH  A4001 (-4.5A)
SAH  A4001 (-2.9A)
SAH  A4001 (-4.0A)
 0.37A 3ou6B-2i62A:
17.6		 3ou6B-2i62A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iip NICOTINAMIDE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		3 TYR A  20
ASP A  85
ASP A 142
 SAH  A4001 (-4.6A)
SAH  A4001 (-2.6A)
SAH  A4001 (-3.7A)
 0.28A 3ou6B-2iipA:
17.3		 3ou6B-2iipA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iiz MELANIN BIOSYNTHESIS
PROTEIN TYRA,
PUTATIVE

(Shewanella
oneidensis) 		PF04261
(Dyp_perox) 		3 TYR A 179
ASP A 265
ASP A 232
 None
 0.78A 3ou6B-2iizA:
undetectable		 3ou6B-2iizA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqe OMPA DOMAIN PROTEIN
TRANSMEMBRANE
REGION-CONTAINING
PROTEIN

(Escherichia
coli) 		PF00691
(OmpA) 		3 TYR A 248
ASP A 241
ASP A 301
 None
 0.74A 3ou6B-2mqeA:
undetectable		 3ou6B-2mqeA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3e NEUROLYSIN

(Rattus
norvegicus) 		PF01432
(Peptidase_M3) 		3 TYR A  49
ASP A 110
ASP A  84
 None
 0.90A 3ou6B-2o3eA:
undetectable		 3ou6B-2o3eA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ptz ENOLASE

(Trypanosoma
brucei) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		3 TYR A  44
ASP A 295
ASP A 251
 None
 0.56A 3ou6B-2ptzA:
undetectable		 3ou6B-2ptzA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe6 UNCHARACTERIZED
PROTEIN TFU_2867

(Thermobifida
fusca) 		PF04672
(Methyltransf_19) 		3 TYR A  26
ASP A 110
ASP A 135
 SAM  A 400 ( 3.8A)
SAM  A 400 (-2.7A)
SAM  A 400 (-3.4A)
 0.70A 3ou6B-2qe6A:
13.4		 3ou6B-2qe6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxr BOTULINUM NEUROTOXIN
TYPE G

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		3 TYR A1107
ASP A1179
ASP A1183
 None
 0.73A 3ou6B-2vxrA:
undetectable		 3ou6B-2vxrA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5o ALPHA-L-ARABINOFURAN
OSIDASE

(Fusarium
graminearum) 		no annotation 3 TYR A 184
ASP A 214
ASP A 266
 None
 0.67A 3ou6B-2w5oA:
undetectable		 3ou6B-2w5oA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9f CELL DIVISION
PROTEIN KINASE 4

(Homo sapiens) 		PF00069
(Pkinase) 		3 TYR B 191
ASP B 196
ASP B 129
 None
 0.90A 3ou6B-2w9fB:
undetectable		 3ou6B-2w9fB:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 TYR A 731
ASP A 688
ASP A 703
 None
GOL  A1922 (-2.4A)
None
 0.71A 3ou6B-2wanA:
undetectable		 3ou6B-2wanA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wg3 DESERT HEDGEHOG
PROTEIN N-PRODUCT

(Homo sapiens) 		PF01085
(HH_signal) 		3 TYR A 175
ASP A 148
ASP A 130
 None
ZN  A1199 (-2.0A)
None
 0.91A 3ou6B-2wg3A:
undetectable		 3ou6B-2wg3A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu2 UPF0271 PROTEIN
PA4511

(Pseudomonas
aeruginosa) 		PF03746
(LamB_YcsF) 		3 TYR A 179
ASP A 176
ASP A 234
 None
 0.87A 3ou6B-2xu2A:
undetectable		 3ou6B-2xu2A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster) 		PF03159
(XRN_N) 		3 TYR A 202
ASP A 205
ASP A 288
 None
 0.81A 3ou6B-2y35A:
2.4		 3ou6B-2y35A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z23 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		3 TYR A 210
ASP A 511
ASP A 502
 None
 0.86A 3ou6B-2z23A:
undetectable		 3ou6B-2z23A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zk9 PROTEIN-GLUTAMINASE

(Chryseobacterium
proteolyticum) 		no annotation 3 TYR X  82
ASP X  40
ASP X 179
 GOL  X 201 ( 4.7A)
None
None
 0.73A 3ou6B-2zk9X:
undetectable		 3ou6B-2zk9X:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zux YESW PROTEIN

(Bacillus
subtilis) 		no annotation 3 TYR A 514
ASP A 457
ASP A 409
 None
CA  A 635 (-2.9A)
None
 0.86A 3ou6B-2zuxA:
undetectable		 3ou6B-2zuxA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a55 PROTEIN-GLUTAMINASE

(Chryseobacterium
proteolyticum) 		no annotation 3 TYR A 196
ASP A 154
ASP A 293
 None
 0.79A 3ou6B-3a55A:
undetectable		 3ou6B-3a55A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a71 EXO-ARABINANASE

(Penicillium
chrysogenum) 		no annotation 3 TYR A 188
ASP A 218
ASP A 267
 None
 0.68A 3ou6B-3a71A:
undetectable		 3ou6B-3a71A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3au0 CLUMPING FACTOR B

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		3 TYR A 359
ASP A 270
ASP A 272
 None
 0.88A 3ou6B-3au0A:
undetectable		 3ou6B-3au0A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0b CONSERVED ARCHAEAL
PROTEIN Q6M145

(Methanococcus
maripaludis) 		PF01968
(Hydantoinase_A) 		3 TYR A 194
ASP A 200
ASP A 224
 None
 0.82A 3ou6B-3c0bA:
undetectable		 3ou6B-3c0bA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9f 5'-NUCLEOTIDASE

(Candida
albicans) 		PF00149
(Metallophos) 		3 TYR A 228
ASP A 259
ASP A 240
 None
 0.82A 3ou6B-3c9fA:
undetectable		 3ou6B-3c9fA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		3 TYR A  36
ASP A 168
ASP A 113
 None
 0.79A 3ou6B-3coiA:
undetectable		 3ou6B-3coiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dpi NAD+ SYNTHETASE

(Burkholderia
pseudomallei) 		PF02540
(NAD_synthase) 		3 TYR A 155
ASP A 184
ASP A 221
 None
 0.93A 3ou6B-3dpiA:
2.1		 3ou6B-3dpiA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed5 YFNB

(Bacillus
subtilis) 		PF13419
(HAD_2) 		3 TYR A 160
ASP A 186
ASP A  13
 None
FMT  A 237 ( 4.8A)
None
 0.83A 3ou6B-3ed5A:
undetectable		 3ou6B-3ed5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdn R-OXYNITRILE LYASE
ISOENZYME 1

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		3 TYR A 368
ASP A 395
ASP A 324
 None
 0.85A 3ou6B-3gdnA:
2.4		 3ou6B-3gdnA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go4 PROTEIN OF UNKNOWN
FUNCTION DUF574

(Streptomyces
avermitilis) 		PF04672
(Methyltransf_19) 		3 TYR A  27
ASP A 111
ASP A 138
 SAH  A 277 (-4.3A)
SAH  A 277 (-2.7A)
SAH  A 277 (-3.5A)
 0.78A 3ou6B-3go4A:
12.7		 3ou6B-3go4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 TYR A 194
ASP A 461
ASP A 565
 None
 0.86A 3ou6B-3gwjA:
undetectable		 3ou6B-3gwjA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhr HUMAN GROWTH HORMONE
HUMAN GROWTH HORMONE
RECEPTOR (HGHBP)

(Homo sapiens;
Homo sapiens) 		PF00103
(Hormone_1)
PF00041
(fn3)
PF09067
(EpoR_lig-bind) 		3 TYR B 107
ASP B 126
ASP A 169
 None
 0.91A 3ou6B-3hhrB:
undetectable		 3ou6B-3hhrB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldg PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.472

(Streptococcus
mutans) 		PF01170
(UPF0020)
PF02926
(THUMP) 		3 TYR A 363
ASP A 370
ASP A 347
 None
 0.81A 3ou6B-3ldgA:
8.1		 3ou6B-3ldgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		3 TYR A 507
ASP A 514
ASP A 425
 None
 0.79A 3ou6B-3lppA:
undetectable		 3ou6B-3lppA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpp BOTULINUM NEUROTOXIN
TYPE G

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		3 TYR G1107
ASP G1179
ASP G1183
 None
 0.85A 3ou6B-3mppG:
undetectable		 3ou6B-3mppG:
16.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ou6 SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
luridus) 		PF13649
(Methyltransf_25) 		3 TYR A  22
ASP A  75
ASP A  98
 SAM  A 300 (-4.4A)
SAM  A 300 (-2.8A)
SAM  A 300 (-4.0A)
 0.14A 3ou6B-3ou6A:
39.1		 3ou6B-3ou6A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		3 TYR A 191
ASP A 280
ASP A 224
 None
 0.89A 3ou6B-3pmkA:
undetectable		 3ou6B-3pmkA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qqw PUTATIVE CITRATE
LYASE

(Cupriavidus
pinatubonensis) 		PF03328
(HpcH_HpaI) 		3 TYR A 113
ASP A 173
ASP A 178
 None
 0.81A 3ou6B-3qqwA:
undetectable		 3ou6B-3qqwA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8j PURINE NUCLEOSIDASE,
(IUNH-1)

(Sulfolobus
solfataricus) 		PF01156
(IU_nuc_hydro) 		3 TYR A 221
ASP A 238
ASP A   7
 None
NA  A 401 ( 3.9A)
None
 0.87A 3ou6B-3t8jA:
2.2		 3ou6B-3t8jA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw8 DENN
DOMAIN-CONTAINING
PROTEIN 1B

(Homo sapiens) 		PF02141
(DENN)
PF03455
(dDENN)
PF03456
(uDENN) 		3 TYR A 218
ASP A   3
ASP A 367
 None
 0.93A 3ou6B-3tw8A:
undetectable		 3ou6B-3tw8A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3two MANNITOL
DEHYDROGENASE

(Helicobacter
pylori) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 TYR A 142
ASP A 120
ASP A 124
 None
 0.92A 3ou6B-3twoA:
6.9		 3ou6B-3twoA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3y THREE PRIME REPAIR
EXONUCLEASE 1

(Mus musculus) 		no annotation 3 TYR B 129
ASP B  18
ASP B 193
 None
 0.85A 3ou6B-3u3yB:
undetectable		 3ou6B-3u3yB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsj 2-AMINO-5-CHLOROPHEN
OL 1,6-DIOXYGENASE
ALPHA SUBUNIT

(Comamonas
testosteroni) 		PF02900
(LigB) 		3 TYR A  49
ASP A 118
ASP A  73
 None
None
CL  A 300 (-3.3A)
 0.90A 3ou6B-3vsjA:
undetectable		 3ou6B-3vsjA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxl HIAXHD3

(Humicola
insolens) 		PF04616
(Glyco_hydro_43) 		3 TYR A  62
ASP A  40
ASP A 291
 None
None
B3P  A1560 (-2.7A)
 0.87A 3ou6B-3zxlA:
undetectable		 3ou6B-3zxlA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amf PHOX

(Pseudomonas
fluorescens) 		PF05787
(DUF839) 		3 TYR A 399
ASP A 447
ASP A 337
 None
None
EDO  A1602 ( 3.3A)
 0.86A 3ou6B-4amfA:
undetectable		 3ou6B-4amfA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		3 TYR A 144
ASP A 468
ASP A 348
 None
 0.73A 3ou6B-4be9A:
undetectable		 3ou6B-4be9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cag POLYSACCHARIDE LYASE
FAMILY 11 PROTEIN

(Bacillus
licheniformis) 		PF01839
(FG-GAP) 		3 TYR A 484
ASP A 427
ASP A 379
 None
CA  A 604 (-3.2A)
None
 0.91A 3ou6B-4cagA:
undetectable		 3ou6B-4cagA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 TYR A 593
ASP A 645
ASP A 633
 None
 0.63A 3ou6B-4ddwA:
3.6		 3ou6B-4ddwA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4etq ANTI-VACCINIA D8L
ANTIGEN MURINE
MONOCLONAL IGG2A
ANTIBODY LA5, HEAVY
CHAIN

(Mus musculus) 		no annotation 3 TYR H  28
ASP H 108
ASP H 105
 None
 0.85A 3ou6B-4etqH:
undetectable		 3ou6B-4etqH:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN

(Salmonella
enterica) 		PF00497
(SBP_bac_3) 		3 TYR A  92
ASP A 196
ASP A 130
 None
 0.70A 3ou6B-4f3sA:
undetectable		 3ou6B-4f3sA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glr ANTI-PTAU HEAVY
CHAIN
ANTI-PTAU LIGHT
CHAIN

(Gallus gallus;
Gallus gallus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  32
ASP H 101
ASP I  57
 None
 0.79A 3ou6B-4glrH:
undetectable		 3ou6B-4glrH:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyr GLUCARATE
DEHYDRATASE

(Acidaminococcus
intestini) 		PF13378
(MR_MLE_C) 		3 TYR A 358
ASP A 199
ASP A 225
 None
 0.79A 3ou6B-4hyrA:
undetectable		 3ou6B-4hyrA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpo NUCLEOSIDE
N-RIBOHYDROLASE 3

(Zea mays) 		PF01156
(IU_nuc_hydro) 		3 TYR A 223
ASP A 240
ASP A   6
 None
CA  A 401 (-2.9A)
None
 0.90A 3ou6B-4kpoA:
2.3		 3ou6B-4kpoA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 TYR A 190
ASP A 457
ASP A 560
 None
None
SCN  A 711 (-4.2A)
 0.85A 3ou6B-4l37A:
undetectable		 3ou6B-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ler PUTATIVE OUTER
MEMBRANE PROTEIN,
PROBABLY INVOLVED IN
NUTRIENT BINDING

(Bacteroides
vulgatus) 		PF12771
(SusD-like_2) 		3 TYR A 434
ASP A 124
ASP A  85
 None
 0.86A 3ou6B-4lerA:
undetectable		 3ou6B-4lerA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Geobacter
sulfurreducens) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		3 TYR A 831
ASP A 601
ASP A 606
 None
 0.54A 3ou6B-4nmeA:
3.7		 3ou6B-4nmeA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opu CONSERVED ARCHAEAL
PROTEIN

(Sulfolobus
acidocaldarius) 		PF01266
(DAO) 		3 TYR A 215
ASP A 183
ASP A 181
 GRG  A 503 ( 4.1A)
GRG  A 502 (-3.4A)
None
 0.93A 3ou6B-4opuA:
2.3		 3ou6B-4opuA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtu PUTATIVE
METHYLTRANSFERASE
BUD23

(Saccharomyces
cerevisiae) 		PF08241
(Methyltransf_11) 		3 TYR B  22
ASP B  77
ASP B  99
 SAM  B 301 (-4.6A)
SAM  B 301 (-2.6A)
SAM  B 301 (-3.7A)
 0.53A 3ou6B-4qtuB:
15.5		 3ou6B-4qtuB:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tx2 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Actinoplanes
teichomyceticus) 		PF00668
(Condensation) 		3 TYR B 181
ASP B 145
ASP B 150
 None
 0.94A 3ou6B-4tx2B:
undetectable		 3ou6B-4tx2B:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yt9 PEPTIDYLARGININE
DEIMINASE

(Porphyromonas
gingivalis) 		PF04371
(PAD_porph) 		3 TYR A 367
ASP A 187
ASP A 224
 None
 0.93A 3ou6B-4yt9A:
undetectable		 3ou6B-4yt9A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE

(Caulobacter
vibrioides) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 TYR A 189
ASP A 320
ASP A 315
 BGC  A1343 (-4.2A)
None
None
 0.86A 3ou6B-5a05A:
3.0		 3ou6B-5a05A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3n ANTI-H4K20ME1_SCFV

(Mus musculus) 		PF07686
(V-set) 		3 TYR A  61
ASP A 108
ASP A 111
 None
 0.67A 3ou6B-5b3nA:
undetectable		 3ou6B-5b3nA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brj TWO COMPONENT
RESPONSE REGULATOR

(Agrobacterium
tumefaciens) 		PF00072
(Response_reg) 		3 TYR A 107
ASP A  72
ASP A  11
 None
None
MG  A 201 (-2.5A)
 0.85A 3ou6B-5brjA:
undetectable		 3ou6B-5brjA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Bordetella
bronchiseptica) 		PF01522
(Polysacc_deac_1) 		3 TYR A 252
ASP A 114
ASP A  50
 None
NI  A 401 (-2.5A)
None
 0.90A 3ou6B-5bu6A:
undetectable		 3ou6B-5bu6A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cgz 4-OXALMESACONATE
HYDRATASE

(Pseudomonas
putida) 		PF02585
(PIG-L) 		3 TYR A 203
ASP A  17
ASP A  89
 None
ZN  A 301 (-2.2A)
None
 0.93A 3ou6B-5cgzA:
2.7		 3ou6B-5cgzA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d5t UNCHARACTERIZED
PROTEIN MJ0489

(Methanocaldococcus
jannaschii) 		PF06690
(DUF1188) 		3 TYR A 150
ASP A 140
ASP A 116
 None
 0.93A 3ou6B-5d5tA:
4.1		 3ou6B-5d5tA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d88 PREDICTED PROTEASE
OF THE COLLAGENASE
FAMILY

(Methanopyrus
kandleri) 		PF01136
(Peptidase_U32) 		3 TYR A  40
ASP A  65
ASP A 102
 None
 0.91A 3ou6B-5d88A:
undetectable		 3ou6B-5d88A:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5de0 DEFERROCHELATASE

(Vibrio cholerae) 		PF04261
(Dyp_perox) 		3 TYR A 133
ASP A 135
ASP A 201
 None
 0.81A 3ou6B-5de0A:
undetectable		 3ou6B-5de0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6s INTEGRIN ALPHA-L

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		3 TYR A   1
ASP A 505
ASP A 445
 None
CA  A2003 (-3.4A)
None
 0.88A 3ou6B-5e6sA:
undetectable		 3ou6B-5e6sA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9h ISOCITRATE LYASE

(Fusarium
graminearum) 		PF00463
(ICL) 		3 TYR A 104
ASP A 179
ASP A 126
 None
 0.93A 3ou6B-5e9hA:
undetectable		 3ou6B-5e9hA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 TYR A 195
ASP A  59
ASP A 664
 None
 0.87A 3ou6B-5fp1A:
undetectable		 3ou6B-5fp1A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gai TAIL FIBER PROTEIN

(Salmonella
virus P22) 		no annotation 3 TYR Y 591
ASP Y 603
ASP Y 573
 None
 0.85A 3ou6B-5gaiY:
undetectable		 3ou6B-5gaiY:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjw VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1

(Oryctolagus
cuniculus) 		PF00092
(VWA)
PF08399
(VWA_N)
PF08473
(VGCC_alpha2) 		3 TYR F 349
ASP F 255
ASP F 288
 None
 0.88A 3ou6B-5gjwF:
undetectable		 3ou6B-5gjwF:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqf LACTO-N-BIOSIDASE

(Bifidobacterium
longum) 		no annotation 3 TYR A 370
ASP A 291
ASP A 179
 None
 0.94A 3ou6B-5gqfA:
undetectable		 3ou6B-5gqfA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz3 PREDICTED PROTEIN

(Physcomitrella
patens) 		PF00316
(FBPase) 		3 TYR B 292
ASP B 181
ASP B 137
 PO4  B 402 (-4.8A)
None
None
 0.94A 3ou6B-5iz3B:
undetectable		 3ou6B-5iz3B:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvk UNCHARACTERIZED
PROTEIN

(Bacteroides
cellulosilyticus) 		no annotation 3 TYR A 144
ASP A 141
ASP A 424
 None
 0.83A 3ou6B-5jvkA:
undetectable		 3ou6B-5jvkA:
16.13