SIMILAR PATTERNS OF AMINO ACIDS FOR 3OU6_B_SAMB300_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cjy | PROTEIN (CYTOSOLICPHOSPHOLIPASE A2) (Homo sapiens) |
PF00168(C2)PF01735(PLA2_B) | 5 | ALA A 396GLY A 394GLY A 551SER A 550LEU A 421 | None | 1.16A | 3ou6B-1cjyA:undetectable | 3ou6B-1cjyA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cxa | CYTOCHROME C2 (Rhodobactersphaeroides) |
PF00034(Cytochrom_C) | 5 | LEU A 87TYR A 90ALA A 48TRP A 71HIS A 75 | NoneNoneHEM A 126 (-4.4A)HEM A 126 (-4.0A)None | 1.03A | 3ou6B-1cxaA:undetectable | 3ou6B-1cxaA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eso | CU, ZN SUPEROXIDEDISMUTASE (Escherichiacoli) |
PF00080(Sod_Cu) | 5 | LEU A 85ALA A 143GLY A 145ALA A 55HIS A 118 | NoneNoneNoneNone CU A 150 ( 3.2A) | 1.14A | 3ou6B-1esoA:undetectable | 3ou6B-1esoA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyd | ARABINANENDO-1,5-ALPHA-L-ARABINOSIDASE A (Cellvibriojaponicus) |
PF04616(Glyco_hydro_43) | 5 | GLY B 239GLY B 288SER B 247ALA B 236HIS B 291 | None | 1.14A | 3ou6B-1gydB:undetectable | 3ou6B-1gydB:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1idu | VANADIUMCHLOROPEROXIDASE (Curvulariainaequalis) |
PF01569(PAP2) | 5 | LEU A 241GLY A 409GLY A 552ALA A 341HIS A 239 | None | 1.10A | 3ou6B-1iduA:undetectable | 3ou6B-1iduA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itz | TRANSKETOLASE (Zea mays) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA A 134GLY A 132GLY A 432ALA A 176HIS A 424 | None | 0.93A | 3ou6B-1itzA:2.4 | 3ou6B-1itzA:15.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rmg | RHAMNOGALACTURONASEA (Aspergillusaculeatus) |
PF00295(Glyco_hydro_28) | 5 | ALA A 148GLY A 114GLY A 170LEU A 176ALA A 127 | None | 1.06A | 3ou6B-1rmgA:undetectable | 3ou6B-1rmgA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rp0 | THIAZOLEBIOSYNTHETIC ENZYME (Arabidopsisthaliana) |
PF01946(Thi4) | 5 | GLY A 240GLY A 48SER A 49MET A 259ALA A 195 | AHZ A 600 (-3.5A)AHZ A 600 (-3.4A)AHZ A 600 (-3.5A)AHZ A 600 (-3.3A)None | 1.08A | 3ou6B-1rp0A:2.6 | 3ou6B-1rp0A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sbp | SULFATE-BINDINGPROTEIN (Salmonellaenterica) |
PF13531(SBP_bac_11) | 5 | ALA A 173GLY A 132GLY A 44SER A 45ALA A 191 | SO4 A 311 (-3.4A)SO4 A 311 (-3.1A)SO4 A 311 (-3.5A)SO4 A 311 (-4.4A)None | 0.91A | 3ou6B-1sbpA:undetectable | 3ou6B-1sbpA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sbp | SULFATE-BINDINGPROTEIN (Salmonellaenterica) |
PF13531(SBP_bac_11) | 5 | TYR A 10ALA A 173GLY A 132GLY A 44ALA A 191 | SO4 A 311 (-4.8A)SO4 A 311 (-3.4A)SO4 A 311 (-3.1A)SO4 A 311 (-3.5A)None | 1.10A | 3ou6B-1sbpA:undetectable | 3ou6B-1sbpA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ALA B 232GLY B 185GLY B 336SER B 335ALA B 82 | None | 1.06A | 3ou6B-1tqyB:undetectable | 3ou6B-1tqyB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1k | VANILLYL-ALCOHOLOXIDASE (Penicilliumsimplicissimum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | ALA A 112GLY A 109SER A 106LEU A 507ALA A 71 | NoneNoneFAD A1561 ( 4.5A)NoneNone | 1.04A | 3ou6B-1w1kA:undetectable | 3ou6B-1w1kA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv2 | HYPOTHETICALPROTEIN, SIMILAR TOALPHA-ACETOLACTATEDECARBOXYLASE (Staphylococcusaureus) |
PF03306(AAL_decarboxy) | 5 | LEU A 5ALA A 74GLY A 9ALA A 23HIS A 31 | None | 0.98A | 3ou6B-1xv2A:undetectable | 3ou6B-1xv2A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y9k | IAAACETYLTRANSFERASE (Bacillus cereus) |
PF00583(Acetyltransf_1) | 5 | LEU A 81TYR A 50GLY A 48GLY A 77HIS A 83 | None | 1.03A | 3ou6B-1y9kA:undetectable | 3ou6B-1y9kA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yjk | PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE (Rattusnorvegicus) |
PF01082(Cu2_monooxygen)PF03712(Cu2_monoox_C) | 5 | LEU A 317ALA A 290GLY A 252SER A 251ALA A 339 | None | 1.13A | 3ou6B-1yjkA:undetectable | 3ou6B-1yjkA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbs | HYPOTHETICAL PROTEINPG1100 (Porphyromonasgingivalis) |
PF01869(BcrAD_BadFG) | 5 | LEU A 274ALA A 95GLY A 67GLY A 100ALA A 75 | None | 1.14A | 3ou6B-1zbsA:undetectable | 3ou6B-1zbsA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ak3 | ADENYLATE KINASEISOENZYME-3 (Bos taurus) |
PF00406(ADK)PF05191(ADK_lid) | 5 | LEU A 39GLY A 89SER A 35LEU A 77ALA A 97 | NoneAMP A 226 (-4.7A)NoneNoneNone | 1.14A | 3ou6B-2ak3A:undetectable | 3ou6B-2ak3A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aps | PROTEIN (CU,ZNSUPEROXIDEDISMUTASE) (Actinobacilluspleuropneumoniae) |
PF00080(Sod_Cu) | 5 | LEU A 110ALA A 162GLY A 164LEU A 52HIS A 141 | NoneNoneNoneNone CU A 402 ( 3.1A) | 1.15A | 3ou6B-2apsA:undetectable | 3ou6B-2apsA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avn | UBIQUINONE/MENAQUINONE BIOSYNTHESISMETHYLTRANSFERASE-RELATED PROTEIN (Thermotogamaritima) |
PF08241(Methyltransf_11) | 5 | TYR A 9GLY A 52TRP A 56SER A 73MET A 76 | SAI A1300 (-3.8A)SAI A1300 (-3.5A)NoneSAI A1300 (-4.7A)SAI A1300 ( 4.2A) | 0.72A | 3ou6B-2avnA:19.1 | 3ou6B-2avnA:26.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dgk | GLUTAMATEDECARBOXYLASE BETA (Escherichiacoli) |
PF00282(Pyridoxal_deC) | 5 | ALA A 245GLY A 248TRP A 286GLY A 210HIS A 241 | PLP A1500 (-3.4A)NoneNoneNoneNone | 1.01A | 3ou6B-2dgkA:undetectable | 3ou6B-2dgkA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ecf | DIPEPTIDYL PEPTIDASEIV (Stenotrophomonasmaltophilia) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | LEU A 620ALA A 632GLY A 608GLY A 630ALA A 634 | None | 0.99A | 3ou6B-2ecfA:undetectable | 3ou6B-2ecfA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h3g | BIOSYNTHETIC PROTEIN (Bacillusanthracis) |
PF03309(Pan_kinase) | 5 | LEU X 246ALA X 12GLY X 8SER X 63LEU X 14 | NoneNoneEDO X 501 (-3.6A)NoneNone | 1.15A | 3ou6B-2h3gX:undetectable | 3ou6B-2h3gX:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibn | INOSITOL OXYGENASE (Homo sapiens) |
PF05153(MIOX) | 5 | LEU A 79ALA A 130GLY A 133LEU A 83ALA A 138 | None | 1.12A | 3ou6B-2ibnA:undetectable | 3ou6B-2ibnA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jpd | DNA EXCISION REPAIRPROTEIN ERCC-1 (Homo sapiens) |
PF03834(Rad10) | 5 | LEU A 209TYR A 212GLY A 133LEU A 139ALA A 165 | None | 1.08A | 3ou6B-2jpdA:undetectable | 3ou6B-2jpdA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcq | PUTATIVEDIHYDRODIPICOLINATESYNTHASE (Thermusthermophilus) |
PF00701(DHDPS) | 5 | LEU A 36ALA A 84GLY A 68LEU A 92ALA A 86 | None | 1.03A | 3ou6B-2pcqA:undetectable | 3ou6B-2pcqA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qny | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Mycobacteriumtuberculosis) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 308TYR A 310ALA A 113GLY A 303GLY A 305 | NoneNoneNoneNoneDFD A 760 (-3.6A) | 1.12A | 3ou6B-2qnyA:undetectable | 3ou6B-2qnyA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qo3 | ERYAII ERYTHROMYCINPOLYKETIDE SYNTHASEMODULES 3 AND 4 (Saccharopolysporaerythraea) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 206ALA A 380GLY A 228GLY A 383ALA A 154 | None | 1.13A | 3ou6B-2qo3A:undetectable | 3ou6B-2qo3A:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzp | ACYLAMINO-ACID-RELEASING ENZYME (Aeropyrumpernix) |
PF00326(Peptidase_S9) | 5 | LEU A 455ALA A 467GLY A 443GLY A 465ALA A 469 | None | 0.84A | 3ou6B-2qzpA:2.7 | 3ou6B-2qzpA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5f | TRANSCRIPTIONALREGULATOR, PUTATIVE (Pseudomonassyringae groupgenomosp. 3) |
PF04198(Sugar-bind) | 5 | ALA A 296GLY A 255GLY A 300LEU A 302ALA A 292 | None | 1.07A | 3ou6B-2r5fA:undetectable | 3ou6B-2r5fA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzz | N-METHYL-L-TRYPTOPHAN OXIDASE (Escherichiacoli) |
PF01266(DAO) | 5 | ALA A 16GLY A 18GLY A 11SER A 10MET A 30 | NoneNoneFAD A1373 (-3.4A)NoneNone | 1.05A | 3ou6B-2uzzA:2.3 | 3ou6B-2uzzA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vqa | SLL1358 PROTEIN (Synechocystissp. PCC 6803) |
PF00190(Cupin_1) | 5 | TYR A 350GLY A 269GLY A 348SER A 257HIS A 285 | ACT A1395 (-4.4A)NoneNoneNone MN A1006 ( 3.5A) | 1.13A | 3ou6B-2vqaA:undetectable | 3ou6B-2vqaA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wvg | PYRUVATEDECARBOXYLASE (Zymomonasmobilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 63GLY A 59GLY A 65ALA A 426HIS A 20 | None | 1.15A | 3ou6B-2wvgA:undetectable | 3ou6B-2wvgA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv2 | SUCCINYL-COASYNTHETASE ALPHACHAIN (Aeropyrumpernix) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | LEU A 17ALA A 30GLY A 26GLY A 43ALA A 32 | None | 1.09A | 3ou6B-2yv2A:3.9 | 3ou6B-2yv2A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z01 | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Geobacilluskaustophilus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | GLY A 96GLY A 243LEU A 305ALA A 229HIS A 246 | None | 1.03A | 3ou6B-2z01A:undetectable | 3ou6B-2z01A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2n | VIRGINIAMYCIN BLYASE (Staphylococcusaureus) |
no annotation | 5 | LEU A 196ALA A 153GLY A 149SER A 150LEU A 154 | None | 1.00A | 3ou6B-2z2nA:undetectable | 3ou6B-2z2nA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z37 | CHITINASE (Brassica juncea) |
PF00182(Glyco_hydro_19) | 5 | ALA A 289GLY A 261SER A 266MET A 264LEU A 282 | None | 1.07A | 3ou6B-2z37A:undetectable | 3ou6B-2z37A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z37 | CHITINASE (Brassica juncea) |
PF00182(Glyco_hydro_19) | 5 | TYR A 258ALA A 289SER A 266MET A 264LEU A 282 | None | 1.11A | 3ou6B-2z37A:undetectable | 3ou6B-2z37A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zo4 | METALLO-BETA-LACTAMASE FAMILY PROTEIN (Thermusthermophilus) |
PF00753(Lactamase_B) | 5 | ALA A 172GLY A 174GLY A 99ALA A 191HIS A 75 | NoneNoneNoneNone ZN A 319 (-3.2A) | 1.15A | 3ou6B-2zo4A:undetectable | 3ou6B-2zo4A:24.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0g | HEMOGLOBIN SUBUNITBETA (Cavia porcellus) |
PF00042(Globin) | 5 | ALA B 27GLY B 29GLY B 64LEU B 68HIS B 117 | None | 1.10A | 3ou6B-3a0gB:undetectable | 3ou6B-3a0gB:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3br8 | PROBABLEACYLPHOSPHATASE (Bacillussubtilis) |
PF00708(Acylphosphatase) | 5 | ALA A 31GLY A 48GLY A 82MET A 1ALA A 25 | None | 1.16A | 3ou6B-3br8A:undetectable | 3ou6B-3br8A:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c02 | AQUAGLYCEROPORIN (Plasmodiumfalciparum) |
PF00230(MIP) | 5 | LEU A 69ALA A 53GLY A 51GLY A 57ALA A 30 | GOL A 663 (-4.1A)NoneNoneNoneNone | 1.06A | 3ou6B-3c02A:undetectable | 3ou6B-3c02A:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czx | PUTATIVEN-ACETYLMURAMOYL-L-ALANINE AMIDASE (Neisseriameningitidis) |
PF01520(Amidase_3) | 5 | LEU A 60ALA A 136GLY A 140LEU A 133ALA A 91 | None | 1.08A | 3ou6B-3czxA:undetectable | 3ou6B-3czxA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtn | PUTATIVEMETHYLTRANSFERASEMM_2633 (Methanosarcinamazei) |
PF13649(Methyltransf_25) | 5 | GLY A 52SER A 75MET A 78ALA A 114HIS A 119 | None | 0.61A | 3ou6B-3dtnA:17.6 | 3ou6B-3dtnA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 5 | LEU A 14TYR A 17GLY A 53GLY A 73SER A 74 | SAM A 221 (-4.4A)SAM A 221 (-3.8A)SAM A 221 (-3.2A)SAM A 221 (-3.2A)SAM A 221 (-4.6A) | 0.74A | 3ou6B-3e23A:19.0 | 3ou6B-3e23A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 5 | ALA A 551GLY A 495GLY A 527LEU A 573ALA A 498 | None | 0.91A | 3ou6B-3eqnA:undetectable | 3ou6B-3eqnA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fpz | THIAZOLEBIOSYNTHETIC ENZYME (Saccharomycescerevisiae) |
PF01946(Thi4) | 5 | GLY A 290GLY A 74SER A 75MET A 309ALA A 243 | AHZ A1100 (-3.5A)AHZ A1100 (-3.6A)AHZ A1100 (-3.6A)AHZ A1100 (-3.3A)None | 1.05A | 3ou6B-3fpzA:2.2 | 3ou6B-3fpzA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbx | GLUTAMATEDECARBOXYLASE 1 (Arabidopsisthaliana) |
PF00282(Pyridoxal_deC) | 5 | ALA A 246GLY A 249TRP A 287GLY A 211HIS A 242 | LLP A 277 ( 3.3A)NoneNoneNoneNone | 1.02A | 3ou6B-3hbxA:undetectable | 3ou6B-3hbxA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hut | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 5 | GLY A 163GLY A 261SER A 262ALA A 168TRP A 169 | None | 1.12A | 3ou6B-3hutA:undetectable | 3ou6B-3hutA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lsc | TRIAZINE HYDROLASE (Paenarthrobacteraurescens) |
PF01979(Amidohydro_1) | 5 | TYR A 67ALA A 328GLY A 69GLY A 326TRP A 85 | AOO A 457 (-4.7A)NoneNoneNoneNone | 1.15A | 3ou6B-3lscA:undetectable | 3ou6B-3lscA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m49 | TRANSKETOLASE (Bacillusanthracis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA A 423GLY A 421GLY A 426MET A 128ALA A 449 | None | 1.05A | 3ou6B-3m49A:undetectable | 3ou6B-3m49A:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3now | UNC-45 PROTEIN,SD10334P (Drosophilamelanogaster) |
PF11701(UNC45-central) | 5 | LEU A 472GLY A 495GLY A 490LEU A 488ALA A 511 | None | 0.83A | 3ou6B-3nowA:undetectable | 3ou6B-3nowA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3now | UNC-45 PROTEIN,SD10334P (Drosophilamelanogaster) |
PF11701(UNC45-central) | 5 | LEU A 472GLY A 495GLY A 490LEU A 488ALA A 512 | None | 1.13A | 3ou6B-3nowA:undetectable | 3ou6B-3nowA:14.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ou6 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptomycesluridus) |
PF13649(Methyltransf_25) | 12 | LEU A 12TYR A 15ALA A 54GLY A 56TRP A 60GLY A 76SER A 77MET A 80LEU A 99ALA A 114TRP A 116HIS A 119 | SAM A 300 ( 3.9A)SAM A 300 ( 3.5A)SAM A 300 (-3.4A)SAM A 300 (-3.1A)NoneSAM A 300 (-3.3A)SAM A 300 (-4.5A)SAM A 300 (-4.0A)SAM A 300 (-3.9A)SAM A 300 (-3.6A)NoneSO4 A 301 (-4.0A) | 0.10A | 3ou6B-3ou6A:39.1 | 3ou6B-3ou6A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3px2 | N-METHYLTRANSFERASE (Streptomycesfradiae) |
PF13649(Methyltransf_25) | 5 | TYR A 14ALA A 58GLY A 60SER A 81MET A 84 | SAH A 263 ( 3.9A)SAH A 263 (-3.5A)SAH A 263 (-3.3A)SAH A 263 (-4.7A)SAH A 263 (-4.5A) | 0.75A | 3ou6B-3px2A:17.4 | 3ou6B-3px2A:28.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q98 | TRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 159ALA A 118GLY A 63GLY A 120SER A 65 | None | 1.10A | 3ou6B-3q98A:undetectable | 3ou6B-3q98A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvq | PHOSPHODIESTERASEOLEI02445 (Oleispiraantarctica) |
PF03009(GDPD) | 5 | LEU A 155GLY A 168SER A 148LEU A 182ALA A 173 | NoneNoneG3P A 301 ( 4.4A)NoneNone | 1.08A | 3ou6B-3qvqA:undetectable | 3ou6B-3qvqA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uog | ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 306GLY A 182LEU A 299ALA A 157TRP A 155 | None | 1.12A | 3ou6B-3uogA:4.9 | 3ou6B-3uogA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vw1 | PUTATIVE REGULATORYPROTEIN (Salmonellaenterica) |
PF00440(TetR_N) | 5 | LEU A 109ALA A 17LEU A 54ALA A 12HIS A 61 | None | 1.08A | 3ou6B-3vw1A:undetectable | 3ou6B-3vw1A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w15 | PEROXISOMALTARGETING SIGNAL 2RECEPTOR (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | LEU A 216ALA A 223GLY A 240GLY A 220SER A 219 | NO3 A 401 (-4.4A)NoneNoneNoneNone | 1.00A | 3ou6B-3w15A:undetectable | 3ou6B-3w15A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wai | MALTOSE-BINDINGPERIPLASMIC PROTEIN,TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Escherichiacoli;Archaeoglobusfulgidus) |
PF13416(SBP_bac_8) | 5 | ALA A 162GLY A 165GLY A 191ALA A 168TRP A 158 | None | 1.07A | 3ou6B-3waiA:undetectable | 3ou6B-3waiA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d65 | PORIN 2 (Providenciastuartii) |
PF00267(Porin_1) | 5 | GLY A 191GLY A 175SER A 193LEU A 149ALA A 179 | LDA A1370 ( 4.6A)LDA A1383 ( 4.2A)NoneLDA A1365 ( 4.3A)None | 1.04A | 3ou6B-4d65A:undetectable | 3ou6B-4d65A:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emi | TODA (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | LEU A 394ALA A 350GLY A 349GLY A 344LEU A 352 | None | 1.14A | 3ou6B-4emiA:undetectable | 3ou6B-4emiA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl3 | TYROSINE-PROTEINKINASE SYK (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | LEU A 365TYR A 364ALA A 421GLY A 437LEU A 446 | None | 1.11A | 3ou6B-4fl3A:undetectable | 3ou6B-4fl3A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4na3 | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 397TYR A 403GLY A 352LEU A 326ALA A 426 | None | 0.93A | 3ou6B-4na3A:undetectable | 3ou6B-4na3A:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q05 | ESTERASE E25 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | GLY A 183GLY A 213SER A 185LEU A 276ALA A 209 | None | 1.15A | 3ou6B-4q05A:3.0 | 3ou6B-4q05A:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9d | BENZOYLFORMATEDECARBOXYLASE (Mycolicibacteriumsmegmatis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 81GLY A 83TRP A 407LEU A 72ALA A 55 | None | 1.02A | 3ou6B-4q9dA:3.7 | 3ou6B-4q9dA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9d | BENZOYLFORMATEDECARBOXYLASE (Mycolicibacteriumsmegmatis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | GLY A 83TRP A 407GLY A 79LEU A 72ALA A 55 | None | 0.78A | 3ou6B-4q9dA:3.7 | 3ou6B-4q9dA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qme | AMINOPEPTIDASE N (Neisseriameningitidis) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | LEU A 833ALA A 796GLY A 801LEU A 630HIS A 836 | None | 1.10A | 3ou6B-4qmeA:undetectable | 3ou6B-4qmeA:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qmk | TYPE III SECRETIONSYSTEM EFFECTORPROTEIN EXOU (Pseudomonasfluorescens) |
PF01734(Patatin) | 5 | ALA A 95GLY A 90GLY A 61SER A 60ALA A 261 | None | 1.12A | 3ou6B-4qmkA:undetectable | 3ou6B-4qmkA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4um8 | INTEGRIN ALPHA-VINTEGRIN BETA-6 (Homo sapiens;Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2)PF00362(Integrin_beta)PF17205(PSI_integrin) | 6 | GLY A 157GLY A 175SER A 176LEU B 265ALA A 109HIS A 113 | None | 1.46A | 3ou6B-4um8A:undetectable | 3ou6B-4um8A:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xdt | FAD:PROTEIN FMNTRANSFERASE (Treponemapallidum) |
PF02424(ApbE) | 5 | LEU A 45ALA A 164GLY A 166LEU A 52ALA A 162 | NoneFAD A 401 (-2.6A)NoneFAD A 401 ( 3.9A)FAD A 401 ( 3.2A) | 1.15A | 3ou6B-4xdtA:undetectable | 3ou6B-4xdtA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yqy | PUTATIVEDEHYDROGENASE (Sulfitobactersp. NAS-14.1) |
PF13561(adh_short_C2) | 5 | ALA A 143GLY A 156GLY A 149ALA A 140HIS A 192 | None | 1.12A | 3ou6B-4yqyA:5.8 | 3ou6B-4yqyA:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z26 | PUTATIVE GMC-TYPEOXIDOREDUCTASE R135 (Acanthamoebapolyphagamimivirus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 6 | LEU A 25GLY A 625TRP A 618LEU A 35ALA A 232HIS A 23 | None | 1.34A | 3ou6B-4z26A:2.3 | 3ou6B-4z26A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z26 | PUTATIVE GMC-TYPEOXIDOREDUCTASE R135 (Acanthamoebapolyphagamimivirus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 6 | LEU A 25TYR A 24GLY A 625TRP A 618LEU A 35ALA A 232 | None | 1.49A | 3ou6B-4z26A:2.3 | 3ou6B-4z26A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z3n | PUTATIVE DRUG/SODIUMANTIPORTER (Escherichiacoli) |
PF01554(MatE) | 5 | LEU A 314GLY A 260GLY A 93SER A 94ALA A 83 | NoneNoneNoneNoneOLC A 507 ( 3.9A) | 1.14A | 3ou6B-4z3nA:undetectable | 3ou6B-4z3nA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 5 | LEU A 101GLY A 51GLY A 57LEU A 59ALA A 46 | NoneSO4 A 704 (-3.3A)NoneNoneNone | 1.02A | 3ou6B-5bp8A:undetectable | 3ou6B-5bp8A:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2u | NANOBODY (Camelusdromedarius) |
PF07686(V-set) | 5 | LEU B 17TYR B 90GLY B 117GLY B 7ALA B 93 | None | 1.14A | 3ou6B-5c2uB:undetectable | 3ou6B-5c2uB:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dm3 | L-GLUTAMINESYNTHETASE (Chromohalobactersalexigens) |
PF00120(Gln-synt_C) | 5 | ALA A 239TRP A 96SER A 152LEU A 148ALA A 234 | None | 1.07A | 3ou6B-5dm3A:undetectable | 3ou6B-5dm3A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyt | ADENYLOSUCCINATELYASE (Schistosomamansoni) |
PF00206(Lyase_1)PF10397(ADSL_C) | 5 | LEU A 206ALA A 193GLY A 195GLY A 103LEU A 40 | None | 1.08A | 3ou6B-5eytA:undetectable | 3ou6B-5eytA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g0q | BETA-GLUCURONIDASE (Acidobacteriumcapsulatum) |
PF03662(Glyco_hydro_79n) | 5 | LEU A 307ALA A 394GLY A 469LEU A 356ALA A 383 | None | 0.92A | 3ou6B-5g0qA:undetectable | 3ou6B-5g0qA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF01547(SBP_bac_1) | 5 | LEU A 449GLY A 348GLY A 170SER A 175ALA A 429 | None | 1.05A | 3ou6B-5g5zA:undetectable | 3ou6B-5g5zA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gp4 | GLUTAMATEDECARBOXYLASE (Lactobacillusbrevis) |
no annotation | 5 | ALA C 248GLY C 251TRP C 289GLY C 213HIS C 244 | PLP C 501 (-3.1A)NoneNoneNoneNone | 1.03A | 3ou6B-5gp4C:undetectable | 3ou6B-5gp4C:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h02 | GLYCINE SARCOSINEN-METHYLTRANSFERASE (Methanohalophilusportucalensis) |
PF13649(Methyltransf_25) | 5 | ALA A 67GLY A 69GLY A 89SER A 90MET A 93 | SAH A 301 (-3.9A)SAH A 301 (-3.3A)SAH A 301 (-3.4A)SAH A 301 ( 4.9A)SAH A 301 (-3.9A) | 0.46A | 3ou6B-5h02A:17.0 | 3ou6B-5h02A:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 5 | LEU A 225TYR A 157GLY A 153GLY A 177SER A 178 | None | 1.04A | 3ou6B-5h42A:undetectable | 3ou6B-5h42A:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxs | SODIUM,CALCIUMEXCHANGER (Methanocaldococcusjannaschii) |
PF01699(Na_Ca_ex) | 5 | LEU A 254ALA A 244GLY A 248SER A 249ALA A 239 | None | 1.10A | 3ou6B-5hxsA:undetectable | 3ou6B-5hxsA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5je3 | METHYL TRANSFERASE (Burkholderiaglumae) |
PF13847(Methyltransf_31) | 5 | ALA A 47GLY A 49SER A 71MET A 74ALA A 111 | SAH A 301 (-3.2A)SAH A 301 (-3.6A)SAH A 301 ( 4.8A)SAH A 301 ( 4.5A)SAH A 301 (-3.8A) | 0.44A | 3ou6B-5je3A:16.5 | 3ou6B-5je3A:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp7 | ACETYL-COAACETYLTRANSFERASE (Bacillussubtilis) |
no annotation | 5 | ALA H 356GLY H 113GLY H 352MET H 53ALA H 9 | None | 1.12A | 3ou6B-5lp7H:undetectable | 3ou6B-5lp7H:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2p | TRYPTOPHAN SYNTHASEALPHA CHAIN (Sulfolobussolfataricus) |
no annotation | 5 | LEU A 238TYR A 241ALA A 201GLY A 205GLY A 208 | None | 0.94A | 3ou6B-5n2pA:undetectable | 3ou6B-5n2pA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nxn | PORIN 1 (Providenciastuartii) |
no annotation | 5 | GLY A 193GLY A 177SER A 195LEU A 152ALA A 181 | None | 1.01A | 3ou6B-5nxnA:undetectable | 3ou6B-5nxnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oie | - (-) |
no annotation | 5 | TYR A 375ALA A 419GLY A 430ALA A 32TRP A 436 | NoneNoneNoneNoneGOL A 501 ( 4.4A) | 1.11A | 3ou6B-5oieA:undetectable | 3ou6B-5oieA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olj | DIPEPTIDYL PEPTIDASEIV (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | LEU A 603ALA A 615GLY A 591GLY A 613ALA A 617 | None | 0.94A | 3ou6B-5oljA:undetectable | 3ou6B-5oljA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5onu | OUTER MEMBRANEPROTEIN OMPU (Vibrio cholerae) |
no annotation | 5 | LEU A 138ALA A 219GLY A 231GLY A 233LEU A 217 | None | 1.15A | 3ou6B-5onuA:undetectable | 3ou6B-5onuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7x | NOD FACTOR BINDINGLECTIN-NUCLEOTIDEPHOSPHOHYDROLASE (Vignaunguiculata) |
PF01150(GDA1_CD39) | 5 | LEU F 94ALA F 87GLY F 14SER F 49LEU F 103 | NoneNonePO4 F 502 (-3.4A)NoneNone | 0.99A | 3ou6B-5u7xF:undetectable | 3ou6B-5u7xF:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5um2 | ABC TRANSPORTERSULFATE BINDINGPROTEIN (Xanthomonascitri) |
PF13531(SBP_bac_11) | 5 | ALA A 225GLY A 184GLY A 95SER A 96ALA A 243 | SO4 A 401 (-3.4A)SO4 A 401 (-3.3A)SO4 A 401 (-3.6A)SO4 A 401 (-4.4A)None | 0.89A | 3ou6B-5um2A:undetectable | 3ou6B-5um2A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5um2 | ABC TRANSPORTERSULFATE BINDINGPROTEIN (Xanthomonascitri) |
PF13531(SBP_bac_11) | 5 | TYR A 60ALA A 225GLY A 184GLY A 95ALA A 243 | SO4 A 401 (-4.7A)SO4 A 401 (-3.4A)SO4 A 401 (-3.3A)SO4 A 401 (-3.6A)None | 1.09A | 3ou6B-5um2A:undetectable | 3ou6B-5um2A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yp3 | DIPEPTIDYLAMINOPEPTIDASE 4 (Pseudoxanthomonasmexicana) |
no annotation | 5 | ALA A 635GLY A 611GLY A 633LEU A 681ALA A 637 | None | 1.10A | 3ou6B-5yp3A:undetectable | 3ou6B-5yp3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yp3 | DIPEPTIDYLAMINOPEPTIDASE 4 (Pseudoxanthomonasmexicana) |
no annotation | 5 | LEU A 623ALA A 635GLY A 611GLY A 633ALA A 637 | None | 0.92A | 3ou6B-5yp3A:undetectable | 3ou6B-5yp3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 5 | LEU A1177ALA A1230GLY A1226GLY A1217MET A1221 | None | 1.16A | 3ou6B-6bq1A:undetectable | 3ou6B-6bq1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2h | CYSTATHIONINEBETA-SYNTHASE (Saccharomycescerevisiae) |
no annotation | 5 | ALA A 90GLY A 93GLY A 120LEU A 116ALA A 57 | NoneNone NA A 404 (-4.0A)NoneNone | 1.15A | 3ou6B-6c2hA:2.3 | 3ou6B-6c2hA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gu8 | - (-) |
no annotation | 5 | ALA A 262GLY A 255SER A 278LEU A 133ALA A 227 | NoneEDO A 505 ( 4.9A)NoneNoneNone | 1.08A | 3ou6B-6gu8A:undetectable | 3ou6B-6gu8A:undetectable |