SIMILAR PATTERNS OF AMINO ACIDS FOR 3OEZ_A_STIA601_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dqu ISOCITRATE LYASE

(Aspergillus
nidulans) 		PF00463
(ICL) 		4 LYS A  47
VAL A 187
ILE A  48
ARG A  26
 None
 1.37A 3oezA-1dquA:
undetectable		 3oezA-1dquA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltd FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae) 		PF00173
(Cyt-b5)
PF01070
(FMN_dh) 		4 VAL A 281
ILE A 346
MET A 183
ARG A 353
 None
 1.15A 3oezA-1ltdA:
0.0		 3oezA-1ltdA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p2f RESPONSE REGULATOR

(Thermotoga
maritima) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 LYS A  66
VAL A  48
ILE A  65
ARG A 113
 None
 1.48A 3oezA-1p2fA:
0.0		 3oezA-1p2fA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcw FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae) 		PF01070
(FMN_dh) 		4 VAL A 281
ILE A 346
MET A 183
ARG A 353
 None
 1.20A 3oezA-1qcwA:
0.0		 3oezA-1qcwA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tww DHPS,
DIHYDROPTEROATE
SYNTHASE

(Bacillus
anthracis) 		PF00809
(Pterin_bind) 		4 VAL A 253
ILE A 143
MET A 160
ARG A 219
 None
HH2  A 282 (-4.1A)
None
SO4  A 279 (-3.3A)
 1.44A 3oezA-1twwA:
0.2		 3oezA-1twwA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vi1 FATTY
ACID/PHOSPHOLIPID
SYNTHESIS PROTEIN
PLSX

(Bacillus
subtilis) 		PF02504
(FA_synthesis) 		4 VAL A 165
ILE A 322
MET A 105
ARG A 311
 None
 1.50A 3oezA-1vi1A:
0.0		 3oezA-1vi1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wql IRON-SULFUR PROTEIN
LARGE SUBUNIT OF
CUMENE DIOXYGENASE

(Pseudomonas
fluorescens) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 VAL A 293
ILE A 288
MET A 324
ARG A 371
 None
 1.49A 3oezA-1wqlA:
0.2		 3oezA-1wqlA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xiw T-CELL SURFACE
GLYCOPROTEIN CD3
DELTA CHAIN

(Homo sapiens) 		PF16680
(Ig_4) 		4 VAL B  12
ILE B  20
MET B   1
ARG B  47
 None
 1.40A 3oezA-1xiwB:
undetectable		 3oezA-1xiwB:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, B
SUBUNIT

(Methylococcus
capsulatus) 		PF04744
(Monooxygenase_B) 		4 VAL A  81
ILE A 118
MET A 272
ARG A  43
 None
 1.03A 3oezA-1yewA:
0.0		 3oezA-1yewA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8x DIHYDROLIPOYL
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LYS A 262
VAL A 189
ILE A 174
ARG A  87
 None
 1.01A 3oezA-2a8xA:
undetectable		 3oezA-2a8xA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bud MALES-ABSENT ON THE
FIRST PROTEIN

(Drosophila
melanogaster) 		PF11717
(Tudor-knot) 		4 VAL A 414
ILE A 375
MET A 370
ARG A 394
 None
 1.23A 3oezA-2budA:
undetectable		 3oezA-2budA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxe RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Pyrococcus
horikoshii) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 VAL A 375
ILE A 369
MET A 250
ARG A 383
 None
 1.38A 3oezA-2cxeA:
undetectable		 3oezA-2cxeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7i POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 10

(Homo sapiens) 		PF00535
(Glycos_transf_2)
PF00652
(Ricin_B_lectin) 		4 LYS A 352
ILE A 349
MET A 439
ARG A 388
 None
 1.43A 3oezA-2d7iA:
undetectable		 3oezA-2d7iA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw1 CATROCOLLASTATIN

(Crotalus atrox) 		PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR) 		4 VAL A 329
ILE A 317
MET A 307
ARG A 358
 None
 1.25A 3oezA-2dw1A:
undetectable		 3oezA-2dw1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjv PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF09646
(Gp37) 		4 VAL A   6
ILE A  25
MET A  21
ARG A  67
 None
 1.41A 3oezA-2gjvA:
2.7		 3oezA-2gjvA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8r POLYPHOSPHATE KINASE

(Porphyromonas
gingivalis) 		PF02503
(PP_kinase)
PF13089
(PP_kinase_N)
PF13090
(PP_kinase_C) 		4 LYS A 212
VAL A 299
MET A 144
ARG A 294
 None
 1.16A 3oezA-2o8rA:
undetectable		 3oezA-2o8rA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z83 HELICASE/NUCLEOSIDE
TRIPHOSPHATASE

(Japanese
encephalitis
virus) 		PF00271
(Helicase_C)
PF07652
(Flavi_DEAD) 		4 VAL A 221
ILE A 301
MET A 495
ARG A 242
 None
 1.34A 3oezA-2z83A:
undetectable		 3oezA-2z83A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zf5 GLYCEROL KINASE

(Thermococcus
kodakarensis) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 VAL O 385
ILE O 299
MET O 485
ARG O 470
 None
 1.04A 3oezA-2zf5O:
undetectable		 3oezA-2zf5O:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abi PUTATIVE
UNCHARACTERIZED
PROTEIN PH1688

(Pyrococcus
horikoshii) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 VAL A 113
ILE A  66
MET A 295
ARG A 328
 None
None
NAD  A1001 ( 3.9A)
None
 1.48A 3oezA-3abiA:
undetectable		 3oezA-3abiA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7r ESTERASE

(Staphylococcus
aureus) 		PF07859
(Abhydrolase_3) 		4 VAL A 202
ILE A 182
MET A 149
ARG A 246
 DMS  A1402 ( 4.5A)
None
None
None
 1.35A 3oezA-3d7rA:
undetectable		 3oezA-3d7rA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 LYS A 481
VAL A 541
ILE A 480
ARG A 774
 None
 1.48A 3oezA-3dy5A:
undetectable		 3oezA-3dy5A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fot 15-O-ACETYLTRANSFERA
SE

(Fusarium
sporotrichioides) 		PF07428
(Tri3) 		4 VAL A 468
ILE A 437
MET A 514
ARG A 278
 None
GOL  A 524 ( 4.2A)
None
None
 1.48A 3oezA-3fotA:
undetectable		 3oezA-3fotA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lf4 FLUORESCENT TIMER
PRECURSOR BLUE102

(Discosoma sp.) 		PF01353
(GFP) 		4 VAL B 122
ILE A  29
MET B 136
ARG B  70
 None
None
None
0YG  B  67 ( 4.0A)
 1.45A 3oezA-3lf4B:
undetectable		 3oezA-3lf4B:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 VAL A 335
ILE A 377
MET A  42
ARG A 363
 None
 1.37A 3oezA-3lk6A:
undetectable		 3oezA-3lk6A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1r FORMIMIDOYLGLUTAMASE

(Bacillus
subtilis) 		PF00491
(Arginase) 		4 VAL A 288
ILE A 257
MET A 211
ARG A 300
 None
 1.33A 3oezA-3m1rA:
0.0		 3oezA-3m1rA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 LYS A  25
VAL A 105
ILE A  17
ARG A 100
 None
 1.48A 3oezA-3vr1A:
undetectable		 3oezA-3vr1A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		4 LYS A 235
VAL A 212
ILE A 238
ARG A 322
 None
 1.28A 3oezA-3wv4A:
undetectable		 3oezA-3wv4A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvn NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		4 LYS A 235
VAL A 212
ILE A 238
ARG A 322
 None
 1.25A 3oezA-3wvnA:
undetectable		 3oezA-3wvnA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a7k ALDOS-2-ULOSE
DEHYDRATASE

(Phanerochaete
chrysosporium) 		no annotation 4 VAL A 407
ILE A 395
MET A  97
ARG A 279
 None
 1.45A 3oezA-4a7kA:
undetectable		 3oezA-4a7kA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw4 BETA-KETOACYL
SYNTHASE

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 VAL A  47
ILE A  80
MET A  33
ARG A  58
 None
 1.38A 3oezA-4cw4A:
undetectable		 3oezA-4cw4A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4laf NAD(P)H
DEHYDROGENASE
(QUINONE)

(Pseudomonas sp.
WBC-3) 		PF03358
(FMN_red) 		4 VAL A  35
ILE A  64
MET A  93
ARG A 190
 None
 1.48A 3oezA-4lafA:
undetectable		 3oezA-4lafA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgn CELLULOSE-BINDING,
FAMILY II

(Acidothermus
cellulolyticus) 		no annotation 4 VAL A 490
ILE A 437
MET A 617
ARG A 539
 None
GOL  A 820 ( 4.9A)
GOL  A 822 (-4.0A)
None
 1.44A 3oezA-4lgnA:
undetectable		 3oezA-4lgnA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pu6 L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Phaseolus
vulgaris) 		PF01112
(Asparaginase_2) 		4 VAL B 197
ILE B 292
MET B 320
ARG A  56
 None
 1.11A 3oezA-4pu6B:
undetectable		 3oezA-4pu6B:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE

(Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 VAL B 914
ILE B 892
MET B 697
ARG B 667
 None
 1.23A 3oezA-4qiwB:
undetectable		 3oezA-4qiwB:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qny MITOGEN ACTIVATED
PROTEIN KINASE,
PUTATIVE

(Leishmania
donovani) 		PF00069
(Pkinase) 		4 LYS A  51
ILE A 102
MET A 107
ARG A 148
 ANP  A 402 (-2.8A)
None
None
None
 0.99A 3oezA-4qnyA:
21.3		 3oezA-4qnyA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uz8 ENDO-BETA-1,4-GLUCAN
ASE (CELULASE B)

(Bacillus
halodurans) 		no annotation 4 VAL A 491
ILE A 561
MET A 520
ARG A 531
 None
 1.31A 3oezA-4uz8A:
undetectable		 3oezA-4uz8A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC

(Ricinus
communis) 		PF03405
(FA_desaturase_2) 		4 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 1.04A 3oezA-4v0jA:
undetectable		 3oezA-4v0jA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE

(Homo sapiens) 		PF09764
(Nt_Gln_amidase) 		4 VAL A 190
ILE A 133
MET A 173
ARG A 128
 None
 1.48A 3oezA-4w79A:
undetectable		 3oezA-4w79A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5an9 60S RIBOSOMAL
PROTEIN L3

(Dictyostelium
discoideum) 		PF00297
(Ribosomal_L3) 		4 VAL A 279
ILE A 218
MET A  53
ARG A  24
 C  N3473 ( 4.5A)
None
C  N3384 ( 3.5A)
G  N3339 ( 2.8A)
 1.31A 3oezA-5an9A:
undetectable		 3oezA-5an9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej1 PUTATIVE CELLULOSE
SYNTHASE

(Rhodobacter
sphaeroides) 		PF03170
(BcsB) 		4 VAL B 378
ILE B 340
MET B 438
ARG B 402
 None
 1.15A 3oezA-5ej1B:
undetectable		 3oezA-5ej1B:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 VAL B 765
ILE B 758
MET B 667
ARG B 710
 None
 1.48A 3oezA-5hb4B:
undetectable		 3oezA-5hb4B:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A  27
ILE A 278
MET A  40
ARG A 112
 None
 1.27A 3oezA-5hm5A:
undetectable		 3oezA-5hm5A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iip GLYCINE
BETAINE/CARNITINE/CH
OLINE ABC
TRANSPORTER%2C
ATP-BINDING
PROTEIN%2C PUTATIVE

(Staphylococcus
aureus) 		PF00571
(CBS) 		4 VAL A 344
ILE A 256
MET A 274
ARG A 350
 None
 1.32A 3oezA-5iipA:
undetectable		 3oezA-5iipA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jy9 PUTATIVE SALICYLATE
SYNTHETASE

(Yersinia
enterocolitica) 		PF00425
(Chorismate_bind) 		4 LYS A 193
VAL A 282
ILE A 409
ARG A 314
 None
 1.39A 3oezA-5jy9A:
undetectable		 3oezA-5jy9A:
21.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5l6o EPHRIN TYPE-B
RECEPTOR 3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 1.00A 3oezA-5l6oA:
32.3		 3oezA-5l6oA:
41.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 VAL C2458
ILE C2476
MET C2408
ARG C2452
 None
 1.27A 3oezA-5y3rC:
undetectable		 3oezA-5y3rC:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5znn SORTILIN

(Mus musculus) 		no annotation 4 VAL A 483
ILE A 525
MET A 516
ARG A 653
 None
 1.47A 3oezA-5znnA:
undetectable		 3oezA-5znnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4m MONOTREME LACTATION
PROTEIN

(Ornithorhynchus
anatinus) 		no annotation 4 VAL A 218
ILE A 248
MET A 272
ARG A 328
 None
 1.39A 3oezA-6b4mA:
undetectable		 3oezA-6b4mA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn0 16S RRNA
(GUANINE(1405)-N(7))
-METHYLTRANSFERASE

(Proteus
mirabilis) 		no annotation 4 LYS A 267
VAL A 258
ILE A 264
MET A 202
 None
 1.11A 3oezA-6cn0A:
1.6		 3oezA-6cn0A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cpy GRMZM2G135359
PSEUDOKINASE

(Zea mays) 		no annotation 4 VAL A 480
ILE A 338
MET A 329
ARG A 464
 None
 1.21A 3oezA-6cpyA:
20.2		 3oezA-6cpyA:
13.41