SIMILAR PATTERNS OF AMINO ACIDS FOR 3NXU_B_RITB600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a0c | XYLOSE ISOMERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF01261(AP_endonuc_2) | 5 | PHE A 97ILE A 222PHE A 224ALA A 219ALA A 141 | None | 1.19A | 3nxuB-1a0cA:0.0 | 3nxuB-1a0cA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aye | PROCARBOXYPEPTIDASEA2 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 5 | PHE A 52MET A 22THR A 54ALA A 66ILE A 193 | None | 1.09A | 3nxuB-1ayeA:undetectable | 3nxuB-1ayeA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b1y | PROTEIN(BETA-AMYLASE) (Hordeum vulgare) |
PF01373(Glyco_hydro_14) | 5 | MET A 156LEU A 290ILE A 275ILE A 294ALA A 295 | None | 1.18A | 3nxuB-1b1yA:0.0 | 3nxuB-1b1yA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h17 | FORMATEACETYLTRANSFERASE 1 (Escherichiacoli) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | LEU A 604THR A 616ALA A 523ILE A 588ALA A 487 | None | 1.18A | 3nxuB-1h17A:0.0 | 3nxuB-1h17A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iwp | GLYCEROL DEHYDRATASEALPHA SUBUNIT (Klebsiellapneumoniae) |
PF02286(Dehydratase_LU) | 5 | THR A 263ILE A 72ALA A 108ILE A 88ALA A 85 | None | 1.02A | 3nxuB-1iwpA:0.0 | 3nxuB-1iwpA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqp | DIPEPTIDYL PEPTIDASEI (Rattusnorvegicus) |
PF00112(Peptidase_C1)PF08773(CathepsinC_exc) | 5 | PHE A 80SER A 267THR A 97ILE A 281ALA A 286 | None | 1.19A | 3nxuB-1jqpA:0.0 | 3nxuB-1jqpA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k3b | DIPEPTYDIL-PEPTIDASEI EXCLUSION DOMAINDIPEPTYDIL-PEPTIDASEI LIGHT CHAIN (Homo sapiens) |
PF00112(Peptidase_C1)PF08773(CathepsinC_exc) | 5 | PHE A 80SER B 268THR A 97ILE B 282ALA B 287 | None | 1.15A | 3nxuB-1k3bA:undetectable | 3nxuB-1k3bA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lcy | HTRA2 SERINEPROTEASE (Homo sapiens) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | MET A 127LEU A 110PHE A 208ILE A 101ALA A 85 | None | 1.09A | 3nxuB-1lcyA:undetectable | 3nxuB-1lcyA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pca | PROCARBOXYPEPTIDASEA PCPA (Sus scrofa) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 5 | PHE A 52MET A 22THR A 54ILE A 109ILE A 193 | None | 1.09A | 3nxuB-1pcaA:undetectable | 3nxuB-1pcaA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tff | UBIQUITINTHIOLESTERASEPROTEIN OTUB2 (Homo sapiens) |
PF10275(Peptidase_C65) | 5 | PHE A 102LEU A 64PHE A 74ILE A 189ILE A 227 | None | 1.14A | 3nxuB-1tffA:undetectable | 3nxuB-1tffA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5c | CHITOSANASE (Bacillus sp.(in: Bacteria)) |
PF01270(Glyco_hydro_8) | 5 | MET A 214SER A 191ILE A 188ILE A 144ALA A 141 | None | 1.16A | 3nxuB-1v5cA:undetectable | 3nxuB-1v5cA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v7v | CHITOBIOSEPHOSPHORYLASE (Vibrioproteolyticus) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 5 | PHE A 448MET A 440PHE A 730ALA A 511ALA A 468 | None | 0.90A | 3nxuB-1v7vA:undetectable | 3nxuB-1v7vA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w74 | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEA (Mycobacteriumtuberculosis) |
PF00160(Pro_isomerase) | 5 | PHE A 127PHE A 107PHE A 71ILE A 148ALA A 29 | None | 1.20A | 3nxuB-1w74A:undetectable | 3nxuB-1w74A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | MET A 433PHE A 78ILE A 323ALA A 346ALA A 389 | ESL A 471 (-4.7A)ESL A 471 ( 4.9A)NoneNoneNone | 1.14A | 3nxuB-1x8vA:34.5 | 3nxuB-1x8vA:25.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avt | DNA POLYMERASE IIIBETA SUBUNIT (Streptococcuspyogenes) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | PHE A 11LEU A 77PHE A 82ILE A 2ALA A 74 | None | 1.12A | 3nxuB-2avtA:undetectable | 3nxuB-2avtA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2boa | CARBOXYPEPTIDASE A4 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 5 | PHE A1052MET A1022THR A1054ALA A1066ILE A1193 | None | 1.10A | 3nxuB-2boaA:undetectable | 3nxuB-2boaA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cbn | RIBONUCLEASE Z (Escherichiacoli) |
PF12706(Lactamase_B_2) | 5 | LEU A 89THR A 20ILE A 118ILE A 126ALA A 136 | None | 1.18A | 3nxuB-2cbnA:undetectable | 3nxuB-2cbnA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5i | AZO REDUCTASE (Escherichiacoli) |
PF02525(Flavodoxin_2) | 5 | LEU A 4ILE A 91ALA A 134ILE A 197ALA A 193 | None | 1.20A | 3nxuB-2d5iA:undetectable | 3nxuB-2d5iA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkh | 3-HYDROXYBENZOATEHYDROXYLASE (Comamonastestosteroni) |
PF01494(FAD_binding_3)PF07976(Phe_hydrox_dim) | 5 | PHE A 370PHE A 90ALA A 91ILE A 77ALA A 78 | None | 1.10A | 3nxuB-2dkhA:undetectable | 3nxuB-2dkhA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkj | SERINEHYDROXYMETHYLTRANSFERASE (Thermusthermophilus) |
PF00464(SHMT) | 5 | PHE A 314MET A 374THR A 306ILE A 364ALA A 363 | None | 1.08A | 3nxuB-2dkjA:undetectable | 3nxuB-2dkjA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9q | 11S GLOBULIN SUBUNITBETA (Cucurbitamaxima) |
PF00190(Cupin_1) | 5 | SER A 81LEU A 322PHE A 131ILE A 100ALA A 99 | None | 0.94A | 3nxuB-2e9qA:undetectable | 3nxuB-2e9qA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h4t | CARNITINEO-PALMITOYLTRANSFERASE II, MITOCHONDRIAL (Rattusnorvegicus) |
PF00755(Carn_acyltransf) | 5 | LEU A 587PHE A 134PHE A 471ALA A 470ILE A 621 | None | 1.08A | 3nxuB-2h4tA:undetectable | 3nxuB-2h4tA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ho5 | OXIDOREDUCTASE,GFO/IDH/MOCA FAMILY (Streptococcuspneumoniae) |
PF01408(GFO_IDH_MocA) | 5 | PHE A 63LEU A 55PHE A 58ILE A 68ALA A 79 | None | 1.14A | 3nxuB-2ho5A:undetectable | 3nxuB-2ho5A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iwz | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE (Homo sapiens) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | THR A 383PHE A 267ILE A 363ALA A 362ALA A 452 | None | 1.09A | 3nxuB-2iwzA:undetectable | 3nxuB-2iwzA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lgh | UNCHARACTERIZEDPROTEIN (Aeromonashydrophila) |
PF08327(AHSA1) | 5 | PHE A 81THR A 71ILE A 124ILE A 3ALA A 108 | None | 1.16A | 3nxuB-2lghA:undetectable | 3nxuB-2lghA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf4 | HYBRID POLYKETIDESYNTHASE-NONRIBOSOMAL PEPTIDESYNTHETASE (Streptomycesvirginiae) |
PF00550(PP-binding) | 5 | PHE A6763LEU A6745THR A6765PHE A6776ILE A6806 | None | 1.01A | 3nxuB-2mf4A:undetectable | 3nxuB-2mf4A:11.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg8 | DPGC (Streptomycestoyocaensis) |
PF00378(ECH_1) | 5 | PHE A 412ILE A 324ALA A 319ILE A 294ALA A 233 | NoneOXY A 3 (-3.9A)OXY A 3 (-3.2A)YE1 A 997 ( 4.4A)YE1 A 997 (-3.9A) | 0.92A | 3nxuB-2pg8A:undetectable | 3nxuB-2pg8A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv5 | UNCHARACTERIZEDPROTEIN ATU2773 (Agrobacteriumfabrum) |
PF04748(Polysacc_deac_2) | 5 | SER A 376LEU A 204ILE A 372ALA A 362ALA A 358 | None | 1.15A | 3nxuB-2qv5A:undetectable | 3nxuB-2qv5A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qyg | RIBULOSEBISPHOSPHATECARBOXYLASE-LIKEPROTEIN 2 (Rhodopseudomonaspalustris) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | PHE A 316THR A 308ILE A 239ALA A 237ILE A 196 | None | 1.12A | 3nxuB-2qygA:undetectable | 3nxuB-2qygA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn7 | GLUCOAMYLASE (Trichodermareesei) |
PF00686(CBM_20)PF00723(Glyco_hydro_15) | 5 | LEU A 177PHE A 109PHE A 187ILE A 133ALA A 132 | None | 1.18A | 3nxuB-2vn7A:undetectable | 3nxuB-2vn7A:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wpg | AMYLOSUCRASE ORALPHA AMYLASE (Xanthomonascampestris) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 6 | PHE A 278LEU A 75PHE A 87ALA A 68ILE A 313ALA A 309 | None | 1.45A | 3nxuB-2wpgA:undetectable | 3nxuB-2wpgA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdq | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Thermosynechococcuselongatus) |
PF00148(Oxidored_nitro) | 5 | PHE A 251LEU A 205THR A 149ILE A 426ALA A 424 | None | 1.12A | 3nxuB-2xdqA:undetectable | 3nxuB-2xdqA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yij | PHOSPHOLIPASEA1-IIGAMMA (Arabidopsisthaliana) |
PF01764(Lipase_3) | 5 | PHE A 282THR A 247PHE A 113ILE A 304ALA A 273 | None | 1.15A | 3nxuB-2yijA:undetectable | 3nxuB-2yijA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aag | GENERALGLYCOSYLATIONPATHWAY PROTEIN (Campylobacterjejuni) |
PF02516(STT3) | 5 | PHE A 550MET A 529LEU A 542PHE A 541ALA A 490 | MLY A 551 ( 4.1A)NoneNoneNoneNone | 1.00A | 3nxuB-3aagA:undetectable | 3nxuB-3aagA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3akk | CTKA (Helicobacterpylori) |
PF07804(HipA_C) | 5 | PHE A 145PHE A 140ILE A 282ILE A 63ALA A 60 | None | 1.03A | 3nxuB-3akkA:undetectable | 3nxuB-3akkA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4a | PROBABLE TRYPTOPHANHYDROXYLASE VIOD (Chromobacteriumviolaceum) |
no annotation | 5 | LEU A 77PHE A 345ILE A 188ILE A 278ALA A 324 | None | 1.11A | 3nxuB-3c4aA:undetectable | 3nxuB-3c4aA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cze | SUCROSE HYDROLASE (Xanthomonascitri) |
PF00128(Alpha-amylase) | 5 | PHE A 277LEU A 74ALA A 67ILE A 312ALA A 308 | None | 1.19A | 3nxuB-3czeA:undetectable | 3nxuB-3czeA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1n | POU DOMAIN, CLASS 6,TRANSCRIPTION FACTOR1 (Homo sapiens) |
PF00046(Homeobox)PF00157(Pou) | 5 | ILE I 147PHE I 150ALA I 151ILE I 185ALA I 184 | None | 1.11A | 3nxuB-3d1nI:undetectable | 3nxuB-3d1nI:14.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3git | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica) |
PF03598(CdhC) | 5 | SER A 594PHE A 677PHE A 628ILE A 635ILE A 658 | None | 1.04A | 3nxuB-3gitA:undetectable | 3nxuB-3gitA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l3f | PROTEIN DOA1 (Saccharomycescerevisiae) |
PF08324(PUL)PF09070(PFU) | 5 | LEU X 576THR X 634ILE X 603ILE X 620ALA X 666 | None | 1.18A | 3nxuB-3l3fX:undetectable | 3nxuB-3l3fX:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 5 | LEU A 474PHE A 378THR A 34ILE A 565ILE A 998 | None | 1.19A | 3nxuB-3ne5A:2.5 | 3nxuB-3ne5A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdf | DIPEPTIDYL PEPTIDASE1 (Homo sapiens) |
PF00112(Peptidase_C1)PF08773(CathepsinC_exc) | 5 | PHE A 80SER A 268THR A 97ILE A 282ALA A 287 | None | 1.18A | 3nxuB-3pdfA:undetectable | 3nxuB-3pdfA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6c | PUTATIVE MAND FAMILYDEHYDRATASE (Pantoeaananatis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | THR A 128ILE A 228ALA A 233ILE A 271ALA A 272 | None | 1.12A | 3nxuB-3t6cA:undetectable | 3nxuB-3t6cA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzi | CRISPR-ASSOCIATEDPROTEIN CAS5, DVULGSUBTYPE (Xanthomonasoryzae) |
PF09704(Cas_Cas5d) | 5 | PHE A 120THR A 123ALA A 143ILE A 39ALA A 36 | None | 1.15A | 3nxuB-3vziA:undetectable | 3nxuB-3vziA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | PHE A 366PHE A 94THR A 370PHE A 26ILE A 362 | None | 1.17A | 3nxuB-4c41A:undetectable | 3nxuB-4c41A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c4a | PROTEIN ARGININEN-METHYLTRANSFERASE7 (Mus musculus) |
PF06325(PrmA) | 5 | PHE A 112LEU A 77PHE A 540ILE A 140ALA A 66 | NoneSAH A1689 ( 4.5A)NoneNoneNone | 1.18A | 3nxuB-4c4aA:undetectable | 3nxuB-4c4aA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2t | SSFS6 (Streptomycessp. SF2575) |
PF00201(UDPGT)PF06722(DUF1205) | 5 | LEU A 169ILE A 130ALA A 125ILE A 6ALA A 34 | None | 1.12A | 3nxuB-4g2tA:undetectable | 3nxuB-4g2tA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl8 | OLIGOPEPTIDE ABCTRANSPORTER OPPAIV (Borreliellaburgdorferi) |
PF00496(SBP_bac_5) | 5 | MET A 177LEU A 167PHE A 174ILE A 133ALA A 140 | None | 1.07A | 3nxuB-4gl8A:undetectable | 3nxuB-4gl8A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4grh | AMINODEOXYCHORISMATESYNTHASE (Stenotrophomonasmaltophilia) |
PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 5 | LEU A 407THR A 34PHE A 393ALA A 411ALA A 236 | None | 1.17A | 3nxuB-4grhA:undetectable | 3nxuB-4grhA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h63 | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 11MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 17MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 22 (Schizosaccharomycespombe) |
PF06179(Med22)PF10156(Med17)no annotation | 5 | SER Q 183ILE V 56ALA V 39ILE K 45ALA K 44 | None | 1.16A | 3nxuB-4h63Q:undetectable | 3nxuB-4h63Q:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hrt | GLOBIN-2 A CHAIN (Scapharcainaequivalvis) |
PF00042(Globin) | 5 | THR A 121PHE A 97ALA A 98ILE A 106ALA A 110 | NoneHEM A 201 (-4.4A)NoneHEM A 201 (-4.4A)HEM A 201 ( 4.8A) | 1.13A | 3nxuB-4hrtA:undetectable | 3nxuB-4hrtA:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ij4 | CHITINASE A (Gemmabryumcoronatum) |
PF00182(Glyco_hydro_19) | 5 | SER A 62PHE A 12ILE A 58ALA A 136ALA A 126 | None | 1.01A | 3nxuB-4ij4A:undetectable | 3nxuB-4ij4A:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4js5 | EXODEOXYRIBONUCLEASEI (Escherichiacoli) |
PF00929(RNase_T)PF08411(Exonuc_X-T_C) | 5 | PHE A 236LEU A 309PHE A 164ALA A 312ALA A 320 | None | 1.10A | 3nxuB-4js5A:undetectable | 3nxuB-4js5A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4js5 | EXODEOXYRIBONUCLEASEI (Escherichiacoli) |
PF00929(RNase_T)PF08411(Exonuc_X-T_C) | 5 | PHE A 236MET A 261LEU A 309PHE A 164ALA A 312 | None | 0.89A | 3nxuB-4js5A:undetectable | 3nxuB-4js5A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kvl | FATTY ACIDALPHA-OXIDASE (Oryza sativa) |
PF03098(An_peroxidase) | 5 | PHE A 379PHE A 272ILE A 593ALA A 433ILE A 146 | PLM A 702 ( 4.7A)NoneNoneNoneNone | 1.10A | 3nxuB-4kvlA:undetectable | 3nxuB-4kvlA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lj2 | CHORISMATE SYNTHASE (Acinetobacterbaumannii) |
PF01264(Chorismate_synt) | 5 | LEU A 340ILE A 230ALA A 233ILE A 331ALA A 328 | None | 1.16A | 3nxuB-4lj2A:undetectable | 3nxuB-4lj2A:21.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 7 | MET A 114SER A 119LEU A 210ILE A 301ALA A 305ILE A 369ALA A 370 | None2QH A 602 (-3.9A)NoneNone2QH A 602 ( 3.6A)HEM A 601 (-4.7A)2QH A 602 ( 3.1A) | 1.04A | 3nxuB-4ny4A:53.1 | 3nxuB-4ny4A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 8 | PHE A 108MET A 114SER A 119PHE A 241ILE A 301ALA A 305ILE A 369ALA A 370 | 2QH A 602 (-4.4A)None2QH A 602 (-3.9A)2QH A 602 (-4.5A)None2QH A 602 ( 3.6A)HEM A 601 (-4.7A)2QH A 602 ( 3.1A) | 0.81A | 3nxuB-4ny4A:53.1 | 3nxuB-4ny4A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 8 | PHE A 108MET A 114SER A 119THR A 224ILE A 301ALA A 305ILE A 369ALA A 370 | 2QH A 602 (-4.4A)None2QH A 602 (-3.9A)NoneNone2QH A 602 ( 3.6A)HEM A 601 (-4.7A)2QH A 602 ( 3.1A) | 0.83A | 3nxuB-4ny4A:53.1 | 3nxuB-4ny4A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 6 | PHE A 108SER A 119THR A 224ILE A 301PHE A 304ALA A 305 | 2QH A 602 (-4.4A)2QH A 602 (-3.9A)NoneNone2QH A 602 (-3.3A)2QH A 602 ( 3.6A) | 1.32A | 3nxuB-4ny4A:53.1 | 3nxuB-4ny4A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oem | DIPEPTIDYL PEPTIDASE1 HEAVY CHAIN (Homo sapiens) |
PF00112(Peptidase_C1)PF08773(CathepsinC_exc) | 5 | PHE A 80SER A 268THR A 97ILE A 282ALA A 287 | NoneEDO A 509 (-4.1A)NoneNoneNone | 1.17A | 3nxuB-4oemA:undetectable | 3nxuB-4oemA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r4g | PUTATIVE LIPOPROTEINYCDA (Bacillussubtilis) |
PF11611(DUF4352)PF17118(DUF5105) | 5 | PHE A 187LEU A 347PHE A 351ALA A 175ILE A 197 | None | 1.05A | 3nxuB-4r4gA:undetectable | 3nxuB-4r4gA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tw0 | SCAVENGER RECEPTORCLASS B MEMBER 2 (Homo sapiens) |
PF01130(CD36) | 5 | LEU A 324PHE A 67PHE A 273ILE A 301ALA A 303 | None | 0.96A | 3nxuB-4tw0A:undetectable | 3nxuB-4tw0A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w6v | DI-/TRIPEPTIDETRANSPORTER (Yersiniaenterocolitica) |
PF00854(PTR2) | 5 | PHE A 186MET A 45PHE A 118PHE A 68ALA A 69 | None | 0.83A | 3nxuB-4w6vA:undetectable | 3nxuB-4w6vA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy5 | ESTERASE (Rhizomucormiehei) |
PF07859(Abhydrolase_3) | 5 | LEU A 106PHE A 85ILE A 295ILE A 46ALA A 44 | None | 1.02A | 3nxuB-4wy5A:undetectable | 3nxuB-4wy5A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xky | DIHYDRODIPICOLINATESYNTHASE (Bacteroidesthetaiotaomicron) |
PF00701(DHDPS) | 5 | MET A 188THR A 47ILE A 151ALA A 147ALA A 112 | None | 1.09A | 3nxuB-4xkyA:undetectable | 3nxuB-4xkyA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg7 | SERINE/THREONINE-PROTEIN KINASE HIPA (Escherichiacoli) |
PF07804(HipA_C)PF13657(Couple_hipA) | 5 | PHE D 315PHE D 236THR D 328ALA D 336ALA D 154 | None | 1.19A | 3nxuB-4yg7D:undetectable | 3nxuB-4yg7D:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zda | ISOCITRATEDEHYDROGENASE (NADP)ICD2 (Mycolicibacteriumsmegmatis) |
PF03971(IDH) | 5 | SER A 616LEU A 25ILE A 8ALA A 32ALA A 635 | None | 1.15A | 3nxuB-4zdaA:undetectable | 3nxuB-4zdaA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4p | UBIQUITIN-CONJUGATING ENZYME E2 Z (Homo sapiens) |
PF00179(UQ_con) | 5 | LEU A 167PHE A 181ILE A 135ALA A 133ILE A 206 | None | 1.04A | 3nxuB-5a4pA:undetectable | 3nxuB-5a4pA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4p | UBIQUITIN-CONJUGATING ENZYME E2 Z (Homo sapiens) |
PF00179(UQ_con) | 5 | MET A 217LEU A 167PHE A 181ILE A 135ALA A 133 | None | 0.73A | 3nxuB-5a4pA:undetectable | 3nxuB-5a4pA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4p | UBIQUITIN-CONJUGATING ENZYME E2 Z (Homo sapiens) |
PF00179(UQ_con) | 5 | MET A 217LEU A 167PHE A 181ILE A 135ILE A 131 | None | 0.91A | 3nxuB-5a4pA:undetectable | 3nxuB-5a4pA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cm6 | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Pseudoalteromonasatlantica) |
PF03480(DctP) | 5 | MET A 50THR A 149PHE A 242ILE A 66ALA A 195 | None | 1.11A | 3nxuB-5cm6A:undetectable | 3nxuB-5cm6A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cm6 | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Pseudoalteromonasatlantica) |
PF03480(DctP) | 5 | MET A 50THR A 238PHE A 242ILE A 66ALA A 195 | NonePYR A 401 (-3.8A)NoneNoneNone | 1.15A | 3nxuB-5cm6A:undetectable | 3nxuB-5cm6A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 5 | LEU A 490PHE A 494ILE A 537ILE A 482ALA A 479 | None | 1.11A | 3nxuB-5djwA:undetectable | 3nxuB-5djwA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlk | TQAA (Penicilliumaethiopicum) |
PF00668(Condensation) | 5 | LEU A 296THR A 356PHE A 307ILE A 457ILE A 475 | None | 0.94A | 3nxuB-5dlkA:undetectable | 3nxuB-5dlkA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyj | GP120 ENV ECTODOMAIN (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 5 | PHE G 176PHE G 159PHE G 309ALA G 316ALA G 204 | None | 1.06A | 3nxuB-5fyjG:undetectable | 3nxuB-5fyjG:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 5 | LEU A 890ILE A 918ALA A 895ILE A 904ALA A 765 | None | 1.16A | 3nxuB-5h42A:undetectable | 3nxuB-5h42A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbh | 30S RIBOSOMALPROTEIN US7 (Pyrococcusabyssi) |
PF00177(Ribosomal_S7) | 5 | ILE H 111PHE H 108ALA H 107ILE H 71ALA H 166 | None | 1.03A | 3nxuB-5jbhH:undetectable | 3nxuB-5jbhH:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjp | NONRIBOSOMAL PEPTIDESYNTHASE (Streptomycessp. MJ635-86F5) |
PF00501(AMP-binding) | 5 | PHE A 89PHE A 95ALA A 77ILE A 32ALA A 31 | None | 1.19A | 3nxuB-5jjpA:undetectable | 3nxuB-5jjpA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN2, MITOCHONDRIALNADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN7, MITOCHONDRIAL (Bos taurus) |
PF00346(Complex1_49kDa)PF01058(Oxidored_q6) | 5 | MET D 164PHE D 178PHE D 168ILE B 87ALA B 89 | None | 1.19A | 3nxuB-5lc5D:undetectable | 3nxuB-5lc5D:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m1q | PHAGE TERMINASELARGE SUBUNIT (Thermus phageG20c) |
PF17289(Terminase_6C) | 5 | ILE A 291PHE A 304ALA A 293ILE A 355ALA A 356 | None | 1.09A | 3nxuB-5m1qA:undetectable | 3nxuB-5m1qA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mmh | HTH-TYPETRANSCRIPTIONALACTIVATOR AMPR (Pseudomonasaeruginosa) |
PF03466(LysR_substrate) | 5 | MET A 241SER A 221THR A 257PHE A 147ALA A 194 | None | 1.19A | 3nxuB-5mmhA:undetectable | 3nxuB-5mmhA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv3 | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Rhodobactersphaeroides) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | THR A 65PHE A 42ILE A 310ILE A 115ALA A 116 | None | 1.20A | 3nxuB-5nv3A:undetectable | 3nxuB-5nv3A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofk | GLYCOSIDE HYDROLASEFAMILY 48 (Caldicellulosiruptorbescii) |
PF00331(Glyco_hydro_10) | 5 | THR A 44ILE A 242PHE A 236ILE A 142ALA A 141 | None | 1.18A | 3nxuB-5ofkA:undetectable | 3nxuB-5ofkA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5okl | AFAMIN (Homo sapiens) |
no annotation | 5 | LEU A 388PHE A 447ALA A 448ILE A 346ALA A 220 | None | 1.06A | 3nxuB-5oklA:undetectable | 3nxuB-5oklA:10.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olj | DIPEPTIDYL PEPTIDASEIV (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | LEU A 600THR A 546ILE A 614ALA A 612ILE A 587 | None | 1.08A | 3nxuB-5oljA:undetectable | 3nxuB-5oljA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swj | PROBABLE ATPSYNTHASE SPAL/MXIB (Shigellaflexneri) |
PF00006(ATP-synt_ab) | 5 | LEU A 91ILE A 229ALA A 232ILE A 298ALA A 300 | None | 0.91A | 3nxuB-5swjA:undetectable | 3nxuB-5swjA:21.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 5 | MET A 114PHE A 215PHE A 241PHE A 304ALA A 305 | NoneRIT A 602 (-4.0A)RIT A 602 (-3.9A)RIT A 602 (-3.7A)HEM A 601 (-3.4A) | 0.77A | 3nxuB-5veuA:48.9 | 3nxuB-5veuA:83.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 5 | MET A 114SER A 119ILE A 301ALA A 305ALA A 370 | NoneRIT A 602 (-3.7A)RIT A 602 ( 4.9A)HEM A 601 (-3.4A)RIT A 602 (-3.3A) | 0.73A | 3nxuB-5veuA:48.9 | 3nxuB-5veuA:83.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 6 | MET A 114SER A 119PHE A 241ILE A 301PHE A 304ALA A 305 | NoneRIT A 602 (-3.7A)RIT A 602 (-3.9A)RIT A 602 ( 4.9A)RIT A 602 (-3.7A)HEM A 601 (-3.4A) | 0.41A | 3nxuB-5veuA:48.9 | 3nxuB-5veuA:83.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x9r | CITRATE-SODIUMSYMPORTER (Klebsiellapneumoniae) |
PF03390(2HCT) | 5 | PHE A 87THR A 349ALA A 122ILE A 420ALA A 423 | None | 1.14A | 3nxuB-5x9rA:undetectable | 3nxuB-5x9rA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn8 | GLYCEROLDEHYDROGENASE (unidentified) |
PF00465(Fe-ADH) | 5 | SER A 288ILE A 293ALA A 355ILE A 256ALA A 252 | None | 1.18A | 3nxuB-5xn8A:undetectable | 3nxuB-5xn8A:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9d | ACYL-COENZYME AOXIDASE 1 (Yarrowialipolytica) |
no annotation | 5 | PHE A 542PHE A 506PHE A 579ALA A 346ILE A 411 | None | 1.11A | 3nxuB-5y9dA:undetectable | 3nxuB-5y9dA:8.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MBH SUBUNITMBH13 NADHDEHYDROGENASESUBUNIT (Pyrococcusfuriosus) |
no annotation | 5 | LEU I 18THR M 86PHE I 14ALA M 71ILE M 230 | None | 0.99A | 3nxuB-6cfwI:undetectable | 3nxuB-6cfwI:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT FMONOVALENT CATION/H+ANTIPORTER SUBUNIT G (Pyrococcusfuriosus) |
no annotation | 5 | SER C 22THR B 72ILE B 16ILE B 44ALA B 43 | None | 1.15A | 3nxuB-6cfwC:undetectable | 3nxuB-6cfwC:11.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e29 | - (-) |
no annotation | 5 | LEU D 229PHE D 241ILE D 217ALA D 189ILE D 206 | None | 1.12A | 3nxuB-6e29D:undetectable | 3nxuB-6e29D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et7 | DIGUANYLATE CYCLASE(GGDEF)DOMAIN-CONTAININGPROTEIN (Idiomarina sp.A28L) |
no annotation | 5 | SER A 592ILE A 534PHE A 535ILE A 612ALA A 613 | None | 1.08A | 3nxuB-6et7A:undetectable | 3nxuB-6et7A:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu6 | AMMONIUM TRANSPORTER (CandidatusKueneniastuttgartiensis) |
no annotation | 5 | PHE A 223THR A 106ILE A 310ALA A 306ILE A 332 | None | 1.12A | 3nxuB-6eu6A:undetectable | 3nxuB-6eu6A:9.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN4 (Mus musculus) |
no annotation | 5 | PHE M 149LEU M 238ILE M 230ALA M 233ALA M 287 | None | 1.08A | 3nxuB-6g2jM:undetectable | 3nxuB-6g2jM:10.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g3u | - (-) |
no annotation | 5 | SER A 613LEU A 24ILE A 7ALA A 31ALA A 632 | None | 1.04A | 3nxuB-6g3uA:undetectable | 3nxuB-6g3uA:undetectable |