SIMILAR PATTERNS OF AMINO ACIDS FOR 3NW2_A_H4BA902_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a80 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE A

(Corynebacterium
sp.) 		PF00248
(Aldo_ket_red) 		3 ARG A 171
ILE A 255
TRP A 221
 None
 1.07A 3nw2A-1a80A:
0.0		 3nw2A-1a80A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5b SERINE/THREONINE
PROTEIN PHOSPHATASE

(Escherichia
virus Lambda) 		PF00149
(Metallophos) 		3 ARG A 162
ILE A 159
TRP A 160
 SO4  A3001 (-3.3A)
None
None
 0.94A 3nw2A-1g5bA:
undetectable		 3nw2A-1g5bA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iiw SLR1257 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF00497
(SBP_bac_3) 		3 ARG A  36
ILE A  30
TRP A 224
 None
 0.99A 3nw2A-1iiwA:
0.0		 3nw2A-1iiwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqg CARBOXYPEPTIDASE A

(Helicoverpa
armigera) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		3 ARG A 302
ILE A 100
TRP A 105
 None
 1.02A 3nw2A-1jqgA:
0.0		 3nw2A-1jqgA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		3 ARG A  67
ILE A 107
TRP A 136
 HEC  A 802 (-4.2A)
None
None
 1.07A 3nw2A-1kb0A:
0.0		 3nw2A-1kb0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltm 36 KDA SOLUBLE LYTIC
TRANSGLYCOSYLASE

(Escherichia
coli) 		PF13406
(SLT_2) 		3 ARG A 164
ILE A 159
TRP A 165
 None
 1.14A 3nw2A-1ltmA:
0.0		 3nw2A-1ltmA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p22 F-BOX/WD-REPEAT
PROTEIN 1A

(Homo sapiens) 		PF00400
(WD40)
PF12937
(F-box-like) 		3 ARG A 384
ILE A 403
TRP A 415
 None
 1.15A 3nw2A-1p22A:
undetectable		 3nw2A-1p22A:
20.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		3 ARG A 375
ILE A 456
TRP A 457
 H4B  A 901 (-3.4A)
H4B  A 901 (-4.7A)
H4B  A 901 ( 3.7A)
 0.61A 3nw2A-1qw5A:
59.9		 3nw2A-1qw5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkx CDP-GLUCOSE-4,6-DEHY
DRATASE

(Yersinia
pseudotuberculosis) 		PF16363
(GDP_Man_Dehyd) 		3 ARG A 146
ILE A 142
TRP A 141
 None
 0.96A 3nw2A-1rkxA:
0.0		 3nw2A-1rkxA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uw4 REGULATOR OF
NONSENSE TRANSCRIPTS
2

(Homo sapiens) 		PF02854
(MIF4G) 		3 ARG B 776
ILE B 816
TRP B 817
 None
 1.14A 3nw2A-1uw4B:
undetectable		 3nw2A-1uw4B:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 121
ILE A 454
TRP A 456
 None
CU  A1503 (-3.4A)
None
 1.00A 3nw2A-1v10A:
undetectable		 3nw2A-1v10A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhs SIMILAR TO
PHOSPHINOTHRICIN
ACETYLTRANSFERASE

(Bacillus
subtilis) 		PF13420
(Acetyltransf_4) 		3 ARG A  39
ILE A  17
TRP A  65
 None
 1.10A 3nw2A-1vhsA:
undetectable		 3nw2A-1vhsA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrm HYPOTHETICAL PROTEIN
TM1553

(Thermotoga
maritima) 		PF02424
(ApbE) 		3 ARG A  58
ILE A 224
TRP A 234
 MPD  A   3 (-3.9A)
None
None
 1.07A 3nw2A-1vrmA:
undetectable		 3nw2A-1vrmA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		3 ARG C 582
ILE C 573
TRP C 574
 None
 0.91A 3nw2A-1w36C:
undetectable		 3nw2A-1w36C:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlt 176AA LONG
HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Sulfurisphaera
tokodaii) 		PF00908
(dTDP_sugar_isom) 		3 ARG A  40
ILE A  13
TRP A 111
 None
 1.03A 3nw2A-1wltA:
undetectable		 3nw2A-1wltA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wms RAS-RELATED PROTEIN
RAB-9A

(Homo sapiens) 		PF00071
(Ras) 		3 ARG A  78
ILE A  11
TRP A  61
 None
 1.05A 3nw2A-1wmsA:
undetectable		 3nw2A-1wmsA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xio ANABAENA SENSORY
RHODOPSIN

(Nostoc sp. PCC
7120) 		PF01036
(Bac_rhodopsin) 		3 ARG A 155
ILE A 146
TRP A 147
 None
None
PEE  A 306 ( 3.6A)
 1.06A 3nw2A-1xioA:
undetectable		 3nw2A-1xioA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z06 RAS-RELATED PROTEIN
RAB-33B

(Mus musculus) 		PF00071
(Ras) 		3 ARG A 105
ILE A  37
TRP A  87
 None
 0.97A 3nw2A-1z06A:
undetectable		 3nw2A-1z06A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1w TRICORN PROTEASE
INTERACTING FACTOR
F3

(Thermoplasma
acidophilum) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ARG A 178
ILE A 212
TRP A 271
 None
 0.94A 3nw2A-1z1wA:
undetectable		 3nw2A-1z1wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486

(Anemonia majano) 		PF01353
(GFP) 		3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.96A 3nw2A-2a46A:
undetectable		 3nw2A-2a46A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayu NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		3 ARG A 355
ILE A 131
TRP A 132
 None
 1.03A 3nw2A-2ayuA:
undetectable		 3nw2A-2ayuA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azo MUTH

(Escherichia
coli) 		PF02976
(MutH) 		3 ARG A   5
ILE A  57
TRP A  58
 None
 0.97A 3nw2A-2azoA:
undetectable		 3nw2A-2azoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b24 NAPHTHALENE
DIOXYGENASE LARGE
SUBUNIT

(Rhodococcus sp.
NCIMB 12038) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		3 ARG A 324
ILE A 199
TRP A 197
 None
 0.94A 3nw2A-2b24A:
undetectable		 3nw2A-2b24A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fkn UROCANATE HYDRATASE

(Bacillus
subtilis) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		3 ARG A 414
ILE A 406
TRP A 408
 None
 1.00A 3nw2A-2fknA:
undetectable		 3nw2A-2fknA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hen EPHRIN TYPE-B
RECEPTOR 2

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		3 ARG A 833
ILE A 822
TRP A 800
 None
 1.00A 3nw2A-2henA:
undetectable		 3nw2A-2henA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i34 ACID PHOSPHATASE

(Bacillus
anthracis) 		PF03767
(Acid_phosphat_B) 		3 ARG A 140
ILE A  95
TRP A  94
 None
 1.09A 3nw2A-2i34A:
undetectable		 3nw2A-2i34A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inc TOLUENE, O-XYLENE
MONOOXYGENASE
OXYGENASE SUBUNIT

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		3 ARG A 116
ILE B 145
TRP B  57
 None
 1.04A 3nw2A-2incA:
undetectable		 3nw2A-2incA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE

(Mycoplasma
mycoides) 		PF01712
(dNK) 		3 ARG A 145
ILE A 139
TRP A 158
 DCP  A1202 (-2.8A)
None
None
 0.94A 3nw2A-2jaqA:
undetectable		 3nw2A-2jaqA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nba PREPILIN-TYPE
CLEAVAGE/METHYLATION
N-TERMINAL DOMAIN
PROTEIN

(Neisseria
subflava) 		PF16732
(ComP_DUS) 		3 ARG A 113
ILE A  64
TRP A  42
 None
 1.09A 3nw2A-2nbaA:
undetectable		 3nw2A-2nbaA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pes URICASE

(Aspergillus
flavus) 		PF01014
(Uricase) 		3 ARG A 128
ILE A 142
TRP A 188
 None
 0.86A 3nw2A-2pesA:
undetectable		 3nw2A-2pesA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7g UROCANATE HYDRATASE

(Pseudomonas
putida) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		3 ARG A 418
ILE A 410
TRP A 412
 None
 0.99A 3nw2A-2v7gA:
undetectable		 3nw2A-2v7gA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsk GLYCOGEN DEBRANCHING
ENZYME

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ARG A 397
ILE A 436
TRP A 392
 None
 1.14A 3nw2A-2wskA:
undetectable		 3nw2A-2wskA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xlr FLAVIN-CONTAINING
MONOOXYGENASE

(Methylophaga
aminisulfidivorans) 		PF00743
(FMO-like) 		3 ARG A 122
ILE A 112
TRP A 109
 None
 1.14A 3nw2A-2xlrA:
undetectable		 3nw2A-2xlrA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyu EPHRIN TYPE-A
RECEPTOR 4,

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		3 ARG A 823
ILE A 812
TRP A 790
 GOL  A1896 (-3.4A)
None
None
 1.14A 3nw2A-2xyuA:
undetectable		 3nw2A-2xyuA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfr DIHYDROFOLATE
REDUCTASE

(Lactobacillus
casei) 		PF00186
(DHFR_1) 		3 ARG A 117
ILE A  13
TRP A   5
 None
NDP  A 163 (-3.8A)
None
 0.98A 3nw2A-3dfrA:
undetectable		 3nw2A-3dfrA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dko EPHRIN TYPE-A
RECEPTOR 7

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		3 ARG A 835
ILE A 824
TRP A 802
 None
 0.90A 3nw2A-3dkoA:
undetectable		 3nw2A-3dkoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmb PUTATIVE GENERAL
STRESS PROTEIN 26
WITH A PNP-OXIDASE
LIKE FOLD

(Xanthomonas
campestris) 		PF16242
(Pyrid_ox_like) 		3 ARG A  88
ILE A  48
TRP A  49
 None
 1.10A 3nw2A-3dmbA:
undetectable		 3nw2A-3dmbA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		3 ARG A 381
ILE A 462
TRP A 463
 H4B  A 902 (-3.9A)
H4B  A 902 (-4.9A)
H4B  A 902 ( 3.6A)
 0.49A 3nw2A-3e7gA:
57.8		 3nw2A-3e7gA:
87.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f9k INTEGRASE

(Human
immunodeficiency
virus 2) 		PF00665
(rve)
PF02022
(Integrase_Zn) 		3 ARG A 107
ILE A 110
TRP A  61
 None
 0.87A 3nw2A-3f9kA:
undetectable		 3nw2A-3f9kA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fsd NTF2-LIKE PROTEIN OF
UNKNOWN FUNCTION IN
NUTRIENT UPTAKE

(Rhodospirillum
rubrum) 		PF14534
(DUF4440) 		3 ARG A  21
ILE A  15
TRP A 113
 None
 1.04A 3nw2A-3fsdA:
undetectable		 3nw2A-3fsdA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		3 ARG A 477
ILE A 488
TRP A 457
 None
 1.08A 3nw2A-3gsiA:
undetectable		 3nw2A-3gsiA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iy7 FRAGMENT FROM
NEUTRALIZING
ANTIBODY F (HEAVY
CHAIN)

(Rattus
norvegicus) 		PF07686
(V-set) 		3 ARG B 164
ILE B 148
TRP B 147
 None
 0.97A 3nw2A-3iy7B:
undetectable		 3nw2A-3iy7B:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq3 LOMBRICINE KINASE

(Urechis caupo) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.87A 3nw2A-3jq3A:
undetectable		 3nw2A-3jq3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		3 ARG A 429
ILE A 349
TRP A 442
 None
SF4  A 801 (-4.1A)
None
 1.03A 3nw2A-3k30A:
undetectable		 3nw2A-3k30A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF03710
(GlnE)
PF08335
(GlnD_UR_UTase) 		3 ARG A 865
ILE A 858
TRP A 942
 None
 1.09A 3nw2A-3k7dA:
undetectable		 3nw2A-3k7dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwd 6-PHOSPHOGLUCONOLACT
ONASE

(Chromohalobacter
salexigens) 		PF01182
(Glucosamine_iso) 		3 ARG A   9
ILE A 188
TRP A 223
 None
 1.03A 3nw2A-3lwdA:
undetectable		 3nw2A-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwd 6-PHOSPHOGLUCONOLACT
ONASE

(Chromohalobacter
salexigens) 		PF01182
(Glucosamine_iso) 		3 ARG A 195
ILE A 188
TRP A 223
 None
 1.08A 3nw2A-3lwdA:
undetectable		 3nw2A-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1u PUTATIVE
GAMMA-D-GLUTAMYL-L-D
IAMINO ACID
ENDOPEPTIDASE

(Desulfovibrio
vulgaris) 		PF00877
(NLPC_P60)
PF12912
(N_NLPC_P60)
PF12913
(SH3_6)
PF12914
(SH3_7) 		3 ARG A 390
ILE A 393
TRP A 388
 None
 1.01A 3nw2A-3m1uA:
undetectable		 3nw2A-3m1uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 ARG A 230
ILE A 237
TRP A 265
 SO4  A 996 (-4.3A)
None
None
 1.03A 3nw2A-3opyA:
undetectable		 3nw2A-3opyA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg9 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
brucei) 		PF00186
(DHFR_1) 		3 ARG A 183
ILE A  51
TRP A  49
 None
 0.89A 3nw2A-3rg9A:
undetectable		 3nw2A-3rg9A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s95 LIM DOMAIN KINASE 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 422
ILE A 537
TRP A 515
 TRS  A 640 (-3.9A)
None
None
 1.13A 3nw2A-3s95A:
undetectable		 3nw2A-3s95A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ARG A 749
ILE A 685
TRP A 689
 None
 1.03A 3nw2A-3s9vA:
undetectable		 3nw2A-3s9vA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 122
ILE A 455
TRP A 457
 None
CU  A 501 (-3.8A)
None
 0.88A 3nw2A-3t6wA:
undetectable		 3nw2A-3t6wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u34 GENERAL STRESS
PROTEIN

(Xanthomonas
citri) 		PF16242
(Pyrid_ox_like) 		3 ARG A 108
ILE A  68
TRP A  69
 None
 1.11A 3nw2A-3u34A:
undetectable		 3nw2A-3u34A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upu ATP-DEPENDENT DNA
HELICASE DDA

(Escherichia
virus T4) 		PF13604
(AAA_30) 		3 ARG A 253
ILE A 342
TRP A 323
 None
 1.13A 3nw2A-3upuA:
undetectable		 3nw2A-3upuA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vc1 GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E

(Streptomyces
coelicolor) 		PF08241
(Methyltransf_11) 		3 ARG A 229
ILE A 226
TRP A 204
 None
GST  A 303 ( 4.9A)
None
 0.96A 3nw2A-3vc1A:
undetectable		 3nw2A-3vc1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w36 NAPH1

(Streptomyces
sp. CNQ525) 		no annotation 3 ARG A 385
ILE A 406
TRP A 411
 None
 0.81A 3nw2A-3w36A:
undetectable		 3nw2A-3w36A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfx EPHRIN TYPE-B
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 823
ILE A 812
TRP A 790
 None
 1.09A 3nw2A-3zfxA:
undetectable		 3nw2A-3zfxA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhc PHYTASE

(Citrobacter
braakii) 		PF00328
(His_Phos_2) 		3 ARG A 158
ILE A 152
TRP A 210
 None
 0.98A 3nw2A-3zhcA:
undetectable		 3nw2A-3zhcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ano ESSB

(Geobacillus
thermodenitrificans) 		PF10140
(YukC) 		3 ARG A 102
ILE A 104
TRP A 136
 None
 0.88A 3nw2A-4anoA:
undetectable		 3nw2A-4anoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw5 EPHRIN TYPE-B
RECEPTOR 4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 295
ILE A 284
TRP A 262
 None
 1.10A 3nw2A-4aw5A:
undetectable		 3nw2A-4aw5A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis) 		PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3) 		3 ARG V 926
ILE V 961
TRP V 939
 None
 0.99A 3nw2A-4bxsV:
undetectable		 3nw2A-4bxsV:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czx PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Neurospora
crassa) 		no annotation 3 ARG A 104
ILE A  64
TRP B 566
 PO4  A 401 (-4.0A)
None
None
 1.10A 3nw2A-4czxA:
undetectable		 3nw2A-4czxA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ARG A 931
ILE A 859
TRP A 885
 None
 1.00A 3nw2A-4ddwA:
undetectable		 3nw2A-4ddwA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0j NON-STRUCTURAL
PROTEIN 2

(Rotavirus A) 		PF02509
(Rota_NS35) 		3 ARG A 227
ILE A 265
TRP A 269
 None
 0.86A 3nw2A-4g0jA:
undetectable		 3nw2A-4g0jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbe GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Saccharomonospora
viridis) 		PF00171
(Aldedh) 		3 ARG A 348
ILE A 342
TRP A 364
 ARG  A 348 ( 0.6A)
ILE  A 342 ( 0.7A)
TRP  A 364 ( 0.5A)
 1.08A 3nw2A-4jbeA:
undetectable		 3nw2A-4jbeA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2k EPHRIN TYPE-A
RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		3 ARG A 816
ILE A 805
TRP A 783
 None
 1.04A 3nw2A-4p2kA:
undetectable		 3nw2A-4p2kA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tsk KETOL-ACID
REDUCTOISOMERASE

(Alicyclobacillus
acidocaldarius) 		PF01450
(IlvC)
PF07991
(IlvN) 		3 ARG A  84
ILE A 291
TRP A 290
 None
 1.15A 3nw2A-4tskA:
undetectable		 3nw2A-4tskA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zb3 NUDIX HYDROLASE 7

(Arabidopsis
thaliana) 		PF00293
(NUDIX) 		3 ARG A  74
ILE A  53
TRP A  54
 None
 1.15A 3nw2A-4zb3A:
undetectable		 3nw2A-4zb3A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3

(Acinetobacter
baumannii) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		3 ARG A1164
ILE A1161
TRP A1134
 None
 0.87A 3nw2A-4zxiA:
undetectable		 3nw2A-4zxiA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3

(Acinetobacter
baumannii) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		3 ARG A1164
ILE A1298
TRP A1134
 None
 1.14A 3nw2A-4zxiA:
undetectable		 3nw2A-4zxiA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5an9 60S RIBOSOMAL
PROTEIN L24

(Dictyostelium
discoideum) 		PF01246
(Ribosomal_L24e) 		3 ARG G  56
ILE G  49
TRP G  51
 None
 1.10A 3nw2A-5an9G:
undetectable		 3nw2A-5an9G:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cs4 ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		3 ARG A1173
ILE A1115
TRP A1131
 None
 1.02A 3nw2A-5cs4A:
0.9		 3nw2A-5cs4A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csa ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00364
(Biotin_lipoyl)
PF08326
(ACC_central) 		3 ARG A1173
ILE A1115
TRP A1131
 None
 1.14A 3nw2A-5csaA:
1.8		 3nw2A-5csaA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 121
ILE A 453
TRP A 455
 None
CU  A 510 (-3.7A)
None
 0.94A 3nw2A-5ehfA:
undetectable		 3nw2A-5ehfA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f2v GTP
PYROPHOSPHOKINASE
YJBM

(Bacillus
subtilis) 		no annotation 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 1.03A 3nw2A-5f2vV:
undetectable		 3nw2A-5f2vV:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fav CHOLINE
TRIMETHYLAMINE-LYASE

(Desulfovibrio
alaskensis) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ARG A  61
ILE A 317
TRP A 314
 None
 1.14A 3nw2A-5favA:
undetectable		 3nw2A-5favA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		3 ARG C 114
ILE C 119
TRP C  93
 None
 1.02A 3nw2A-5flzC:
undetectable		 3nw2A-5flzC:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsy MACRODOMAIN

(Trypanosoma
brucei) 		PF01661
(Macro) 		3 ARG A 169
ILE A  57
TRP A  76
 None
 1.05A 3nw2A-5fsyA:
undetectable		 3nw2A-5fsyA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		3 ARG A 704
ILE A 701
TRP A 690
 None
 1.15A 3nw2A-5gzuA:
undetectable		 3nw2A-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		3 ARG A1190
ILE A1187
TRP A1176
 None
 1.07A 3nw2A-5gzuA:
undetectable		 3nw2A-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3z POLYKETIDE
KETOREDUCTASE SIMC7

(Streptomyces
antibioticus) 		PF13460
(NAD_binding_10) 		3 ARG A 130
ILE A 119
TRP A 126
 None
 1.06A 3nw2A-5l3zA:
undetectable		 3nw2A-5l3zA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6o EPHRIN TYPE-B
RECEPTOR 3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 837
ILE A 826
TRP A 804
 None
 1.01A 3nw2A-5l6oA:
undetectable		 3nw2A-5l6oA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 122
ILE A 455
TRP A 457
 None
CU  A 504 (-3.8A)
None
 0.94A 3nw2A-5mewA:
undetectable		 3nw2A-5mewA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n77 MAGNESIUM TRANSPORT
PROTEIN CORA

(Escherichia
coli) 		PF01544
(CorA) 		3 ARG A  14
ILE A  29
TRP A  28
 None
 1.06A 3nw2A-5n77A:
undetectable		 3nw2A-5n77A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojr -

(-) 		no annotation 3 ARG A  82
ILE A  64
TRP A  70
 None
 1.06A 3nw2A-5ojrA:
undetectable		 3nw2A-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.01A 3nw2A-5oqj1:
undetectable		 3nw2A-5oqj1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.00A 3nw2A-5oqm1:
undetectable		 3nw2A-5oqm1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyj VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		no annotation 3 ARG C 541
ILE C 456
TRP C 458
 None
 1.12A 3nw2A-5oyjC:
undetectable		 3nw2A-5oyjC:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1

(Homo sapiens) 		PF00047
(ig)
PF07679
(I-set)
PF13927
(Ig_3) 		3 ARG X 546
ILE X 464
TRP X 466
 None
 1.00A 3nw2A-5t89X:
undetectable		 3nw2A-5t89X:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tey N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT

(Homo sapiens) 		PF05063
(MT-A70) 		3 ARG A 508
ILE A 503
TRP A 457
 None
 0.96A 3nw2A-5teyA:
undetectable		 3nw2A-5teyA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhe DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Mycobacterium
tuberculosis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 ARG D 113
ILE D 104
TRP D 105
 None
 1.03A 3nw2A-5uheD:
undetectable		 3nw2A-5uheD:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf4 UNCHARACTERIZED
PROTEIN

(Thermus
aquaticus) 		PF03781
(FGE-sulfatase) 		3 ARG A 370
ILE A  93
TRP A 201
 None
 1.06A 3nw2A-5vf4A:
undetectable		 3nw2A-5vf4A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Vibrio harveyi) 		no annotation 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.09A 3nw2A-5yqwA:
undetectable		 3nw2A-5yqwA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byk 14-3-3 PROTEIN
BETA/ALPHA

(Homo sapiens) 		no annotation 3 ARG A  58
ILE A  88
TRP A  61
 None
 0.99A 3nw2A-6bykA:
undetectable		 3nw2A-6bykA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c7v -

(-) 		no annotation 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.14A 3nw2A-6c7vA:
undetectable		 3nw2A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfz ASK1
DAD4

(Chaetomium
thermophilum) 		no annotation 3 ARG A  59
ILE E  44
TRP A  62
 None
 0.95A 3nw2A-6cfzA:
undetectable		 3nw2A-6cfzA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cuf -

(-) 		no annotation 3 ARG 6  31
ILE 6  48
TRP 6  35
 None
 1.06A 3nw2A-6cuf6:
undetectable		 3nw2A-6cuf6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.97A 3nw2A-6ei1A:
undetectable		 3nw2A-6ei1A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5o POLYMERASE BASIC
PROTEIN 2
RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza B
virus) 		no annotation 3 ARG B 622
ILE B 574
TRP C 100
 None
 1.15A 3nw2A-6f5oB:
undetectable		 3nw2A-6f5oB:
12.43