SIMILAR PATTERNS OF AMINO ACIDS FOR 3NK2_X_LDPX433_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0i DNA LIGASE

(Escherichia
virus T7) 		PF01068
(DNA_ligase_A_M) 		4 TYR A 184
MET A 177
LEU A 148
LEU A  76
 None
 1.15A 3nk2X-1a0iA:
undetectable		 3nk2X-1a0iA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1au8 CATHEPSIN G

(Homo sapiens) 		PF00089
(Trypsin) 		4 MET A  30
LEU A 155
LEU A 200
PHE A  45
 None
 1.21A 3nk2X-1au8A:
undetectable		 3nk2X-1au8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsl BACTERIAL LUCIFERASE

(Vibrio harveyi) 		PF00296
(Bac_luciferase) 		4 TYR A  42
LEU A 228
LEU A   8
PHE A 250
 None
 1.25A 3nk2X-1bslA:
0.4		 3nk2X-1bslA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4u NIDOGEN-1

(Mus musculus) 		PF07474
(G2F) 		4 TYR A 546
LEU A 597
PHE A 585
TRP A 466
 None
 1.10A 3nk2X-1h4uA:
undetectable		 3nk2X-1h4uA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hr7 MITOCHONDRIAL
PROCESSING PEPTIDASE
BETA SUBUNIT

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 TYR B 110
MET B 208
LEU B  35
LEU B 130
 None
 1.14A 3nk2X-1hr7B:
0.0		 3nk2X-1hr7B:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khc DNA CYTOSINE-5
METHYLTRANSFERASE
3B2

(Mus musculus) 		PF00855
(PWWP) 		4 MET A 309
LEU A 340
LEU A 287
PHE A 271
 None
 1.12A 3nk2X-1khcA:
undetectable		 3nk2X-1khcA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw7 HYPOTHETICAL PROTEIN
HP0162

(Helicobacter
pylori) 		PF01709
(Transcrip_reg) 		4 ASN A 186
LEU A 194
LEU A  52
PHE A 182
 None
 1.16A 3nk2X-1mw7A:
0.0		 3nk2X-1mw7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyq THREONYL-TRNA
SYNTHETASE 1

(Staphylococcus
aureus) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		4 TYR A 304
MET A 341
LEU A 501
LEU A 303
 None
 1.30A 3nk2X-1nyqA:
0.0		 3nk2X-1nyqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgd PROTEIN
(TRANSKETOLASE)

(Escherichia
coli) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 TYR A  80
LEU A  14
LEU A  75
TRP A 294
 None
 1.27A 3nk2X-1qgdA:
0.0		 3nk2X-1qgdA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh4 CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ASN A  28
MET A  30
LEU A  88
LEU A  23
 None
 1.29A 3nk2X-1qh4A:
undetectable		 3nk2X-1qh4A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ASN A  23
MET A  25
LEU A  83
LEU A  18
 None
 1.24A 3nk2X-1qk1A:
undetectable		 3nk2X-1qk1A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qmh RNA 3'-TERMINAL
PHOSPHATE CYCLASE

(Escherichia
coli) 		PF01137
(RTC)
PF05189
(RTC_insert) 		4 TYR A 274
MET A 192
LEU A 219
LEU A 275
 None
 1.20A 3nk2X-1qmhA:
undetectable		 3nk2X-1qmhA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyr HIGH LEVEL
KASUGAMYCIN
RESISTANCE PROTEIN

(Escherichia
coli) 		PF00398
(RrnaAD) 		4 MET A 123
LEU A 114
LEU A 148
PHE A 124
 None
 1.27A 3nk2X-1qyrA:
undetectable		 3nk2X-1qyrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6r CREATINE KINASE, M
CHAIN

(Oryctolagus
cuniculus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ASN A  27
MET A  29
LEU A  87
LEU A  22
 None
 1.20A 3nk2X-1u6rA:
undetectable		 3nk2X-1u6rA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4n 271AA LONG
HYPOTHETICAL
5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE

(Sulfurisphaera
tokodaii) 		PF01048
(PNP_UDP_1) 		4 TYR A 245
LEU A 142
LEU A 244
PHE A  56
 None
 1.19A 3nk2X-1v4nA:
undetectable		 3nk2X-1v4nA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqu ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE 2

(Nostoc sp. PCC
7120) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 MET A  37
LEU A  41
LEU A 201
TRP A  40
 None
 1.26A 3nk2X-1vquA:
undetectable		 3nk2X-1vquA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrp CREATINE KINASE, M
CHAIN

(Tetronarce
californica) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 ASN A  28
MET A  30
LEU A  88
LEU A  23
 None
 1.21A 3nk2X-1vrpA:
undetectable		 3nk2X-1vrpA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wta 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE

(Aeropyrum
pernix) 		PF01048
(PNP_UDP_1) 		4 TYR A 249
LEU A 146
LEU A 248
PHE A  59
 None
 1.21A 3nk2X-1wtaA:
undetectable		 3nk2X-1wtaA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xly SHE2P

(Saccharomyces
cerevisiae) 		PF11435
(She2p) 		4 ASN A 114
LEU A 136
LEU A 226
PHE A 110
 None
 1.23A 3nk2X-1xlyA:
undetectable		 3nk2X-1xlyA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr5 GENOME POLYPROTEIN

(Rhinovirus B) 		PF00680
(RdRP_1) 		4 TYR A 195
MET A 298
LEU A 194
PHE A 295
 None
 1.28A 3nk2X-1xr5A:
undetectable		 3nk2X-1xr5A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwi SKD1 PROTEIN

(Homo sapiens) 		PF00004
(AAA)
PF09336
(Vps4_C) 		4 TYR A 297
ASN A 279
LEU A 284
LEU A 433
 None
SO4  A 601 ( 3.5A)
None
None
 1.16A 3nk2X-1xwiA:
undetectable		 3nk2X-1xwiA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ya0 SMG-7 TRANSCRIPT
VARIANT 2

(Homo sapiens) 		PF10373
(EST1_DNA_bind)
PF10374
(EST1) 		4 TYR A 261
LEU A 203
LEU A 226
PHE A 303
 None
 1.25A 3nk2X-1ya0A:
undetectable		 3nk2X-1ya0A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywl HYPOTHETICAL UPF0213
PROTEIN EF2693

(Enterococcus
faecalis) 		PF01541
(GIY-YIG) 		4 TYR A  83
LEU A  13
LEU A  84
PHE A   9
 None
 1.22A 3nk2X-1ywlA:
undetectable		 3nk2X-1ywlA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6m CONSERVED
HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF13462
(Thioredoxin_4) 		4 MET A  98
LEU A 123
LEU A  65
PHE A  99
 None
 1.24A 3nk2X-1z6mA:
undetectable		 3nk2X-1z6mA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b61 HOMOSERINE
O-ACETYLTRANSFERASE

(Haemophilus
influenzae) 		PF00561
(Abhydrolase_1) 		4 ASN A 180
LEU A 214
LEU A  49
PHE A 172
 None
 1.29A 3nk2X-2b61A:
undetectable		 3nk2X-2b61A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fdr CONSERVED
HYPOTHETICAL PROTEIN

(Agrobacterium
fabrum) 		PF13419
(HAD_2) 		4 TYR A  35
LEU A  71
LEU A  30
PHE A  46
 None
 1.02A 3nk2X-2fdrA:
undetectable		 3nk2X-2fdrA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsj PROTEIN PPL-2

(Parkia
platycephala) 		PF00704
(Glyco_hydro_18) 		4 TYR A 133
LEU A 105
LEU A 136
PHE A  36
 None
 1.02A 3nk2X-2gsjA:
undetectable		 3nk2X-2gsjA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3d HYPOTHETICAL PROTEIN
ATU1826

(Agrobacterium
fabrum) 		PF02129
(Peptidase_S15) 		4 TYR A 107
MET A 200
LEU A  52
PHE A 192
 None
 1.09A 3nk2X-2i3dA:
undetectable		 3nk2X-2i3dA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jh9 VP4 CORE PROTEIN

(Bluetongue
virus) 		PF05059
(Orbi_VP4) 		4 LEU A 619
LEU A 644
PHE A 569
TRP A 637
 None
 1.25A 3nk2X-2jh9A:
undetectable		 3nk2X-2jh9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN

(Babesia
divergens) 		PF11641
(Antigen_Bd37) 		4 TYR A 132
LEU A 106
LEU A 133
PHE A 181
 None
 1.24A 3nk2X-2jo7A:
undetectable		 3nk2X-2jo7A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2luc PROTEIN S100-A11

(Homo sapiens) 		PF00036
(EF-hand_1)
PF01023
(S_100) 		4 MET A  43
LEU A  40
LEU A  83
PHE A  50
 None
 1.28A 3nk2X-2lucA:
undetectable		 3nk2X-2lucA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o9r BETA-GLUCOSIDASE B

(Paenibacillus
polymyxa) 		PF00232
(Glyco_hydro_1) 		4 TYR A 297
ASN A 248
LEU A 293
LEU A 338
 None
 1.29A 3nk2X-2o9rA:
undetectable		 3nk2X-2o9rA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oux MAGNESIUM
TRANSPORTER

(Enterococcus
faecalis) 		PF00571
(CBS)
PF03448
(MgtE_N) 		4 TYR A  54
LEU A  31
LEU A  53
PHE A  66
 None
 1.25A 3nk2X-2ouxA:
undetectable		 3nk2X-2ouxA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF16073
(SAT) 		4 TYR B 352
ASN B 418
LEU B 386
PHE B 416
 None
 1.30A 3nk2X-2pffB:
undetectable		 3nk2X-2pffB:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6z UROPORPHYRINOGEN
DECARBOXYLASE

(Homo sapiens) 		PF01208
(URO-D) 		4 TYR A  42
LEU A 305
LEU A 341
PHE A  76
 None
 1.23A 3nk2X-2q6zA:
undetectable		 3nk2X-2q6zA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdl CHYMASE 2

(Mesocricetus
auratus) 		PF00089
(Trypsin) 		4 MET A  30
LEU A 155
LEU A 200
PHE A  45
 None
None
SO4  A 247 (-4.0A)
None
 1.20A 3nk2X-2rdlA:
undetectable		 3nk2X-2rdlA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x6k PHOSPHOTIDYLINOSITOL
3 KINASE 59F

(Drosophila
melanogaster) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka) 		4 TYR A 868
MET A 839
LEU A 841
LEU A 921
 None
 1.16A 3nk2X-2x6kA:
undetectable		 3nk2X-2x6kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgo XCOGT

(Xanthomonas
campestris) 		PF13432
(TPR_16)
PF13844
(Glyco_transf_41) 		4 MET A 504
LEU A 501
LEU A 456
PHE A 512
 None
 1.28A 3nk2X-2xgoA:
1.7		 3nk2X-2xgoA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8d ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ASN A2344
MET A2341
LEU A2391
TRP A2398
 None
 1.28A 3nk2X-2y8dA:
undetectable		 3nk2X-2y8dA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9y ISWI ONE COMPLEX
PROTEIN 3

(Saccharomyces
cerevisiae) 		PF15612
(WHIM1) 		4 TYR B 178
LEU B 257
LEU B 214
PHE B 205
 None
 1.17A 3nk2X-2y9yB:
undetectable		 3nk2X-2y9yB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anv D-SERINE DEHYDRATASE

(Gallus gallus) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 TYR A 358
LEU A   7
LEU A  15
PHE A 245
 None
 1.23A 3nk2X-3anvA:
undetectable		 3nk2X-3anvA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebl GIBBERELLIN RECEPTOR
GID1

(Oryza sativa) 		PF07859
(Abhydrolase_3) 		4 TYR A 329
LEU A 348
LEU A 224
PHE A 118
 None
 1.09A 3nk2X-3eblA:
undetectable		 3nk2X-3eblA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fh6 MALTOSE TRANSPORT
SYSTEM PERMEASE
PROTEIN MALF

(Escherichia
coli) 		PF00528
(BPD_transp_1)
PF14785
(MalF_P2) 		4 ASN F 440
LEU F 446
LEU F 379
PHE F 436
 None
 1.18A 3nk2X-3fh6F:
undetectable		 3nk2X-3fh6F:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD

(Bacillus
anthracis) 		no annotation 4 TYR L 189
LEU L 206
LEU L 185
PHE S 375
 None
 1.14A 3nk2X-3g9kL:
undetectable		 3nk2X-3g9kL:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdx SUSD SUPERFAMILY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 TYR A 136
LEU A 141
PHE A 122
TRP A  42
 None
 1.25A 3nk2X-3hdxA:
undetectable		 3nk2X-3hdxA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5t AMINOTRANSFERASE

(Rhodobacter
sphaeroides) 		PF00202
(Aminotran_3) 		4 ASN A 322
LEU A 159
LEU A 300
PHE A 320
 None
 1.26A 3nk2X-3i5tA:
undetectable		 3nk2X-3i5tA:
23.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k7t 6-HYDROXY-L-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01593
(Amino_oxidase) 		5 ASN A 166
MET A 167
LEU A 183
PHE A 326
TRP A 371
 None
 0.18A 3nk2X-3k7tA:
64.7		 3nk2X-3k7tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k7t 6-HYDROXY-L-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01593
(Amino_oxidase) 		5 MET A 167
LEU A 183
LEU A 198
PHE A 326
TRP A 371
 None
 0.75A 3nk2X-3k7tA:
64.7		 3nk2X-3k7tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k7t 6-HYDROXY-L-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01593
(Amino_oxidase) 		5 TYR A  59
MET A 167
LEU A 183
LEU A 198
TRP A 371
 None
 0.82A 3nk2X-3k7tA:
64.7		 3nk2X-3k7tA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4d STEROL 14-ALPHA
DEMETHYLASE

(Leishmania
infantum) 		PF00067
(p450) 		4 MET A 283
LEU A 264
LEU A 126
PHE A 109
 None
None
HEM  A 481 (-4.3A)
TPF  A 490 (-4.5A)
 1.15A 3nk2X-3l4dA:
undetectable		 3nk2X-3l4dA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE

(Oleispira
antarctica) 		PF00857
(Isochorismatase) 		4 TYR A 138
LEU A 172
LEU A 115
PHE A  98
 None
 1.22A 3nk2X-3lqyA:
undetectable		 3nk2X-3lqyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o53 PROTEIN LRIM1

(Anopheles
gambiae) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 TYR A 316
LEU A 250
LEU A 266
PHE A 280
 None
 1.29A 3nk2X-3o53A:
undetectable		 3nk2X-3o53A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1

(Anopheles
gambiae) 		PF00560
(LRR_1) 		4 TYR A 316
LEU A 250
LEU A 266
PHE A 280
 None
 1.20A 3nk2X-3ojaA:
undetectable		 3nk2X-3ojaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ryl PROTEIN VPA1370

(Vibrio
parahaemolyticus) 		no annotation 4 TYR A 460
LEU A 409
LEU A 427
PHE A 448
 None
 1.13A 3nk2X-3rylA:
undetectable		 3nk2X-3rylA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stt METHYLKETONE
SYNTHASE I

(Solanum
habrochaites) 		PF12697
(Abhydrolase_6) 		4 TYR A 202
LEU A  65
LEU A 197
PHE A 109
 None
 1.27A 3nk2X-3sttA:
undetectable		 3nk2X-3sttA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t66 NICKEL ABC
TRANSPORTER
(NICKEL-BINDING
PROTEIN)

(Bacillus
halodurans) 		PF00496
(SBP_bac_5) 		4 TYR A 402
ASN A 243
LEU A 381
PHE A 453
 None
 1.25A 3nk2X-3t66A:
undetectable		 3nk2X-3t66A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3trg ACYLPHOSPHATASE

(Coxiella
burnetii) 		PF00708
(Acylphosphatase) 		4 LEU A  35
LEU A  51
PHE A  24
TRP A  66
 None
 1.29A 3nk2X-3trgA:
undetectable		 3nk2X-3trgA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A  22
LEU A 479
PHE A 436
TRP A 411
 None
 1.23A 3nk2X-3v9eA:
undetectable		 3nk2X-3v9eA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wg6 CONJUGATED
POLYKETONE REDUCTASE
C1

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		4 TYR A  27
LEU A 114
LEU A  39
PHE A  21
 None
 1.09A 3nk2X-3wg6A:
undetectable		 3nk2X-3wg6A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az3 LYSOSOMAL PROTECTIVE
PROTEIN 32 KDA CHAIN

(Homo sapiens) 		PF00450
(Peptidase_S10) 		4 TYR A  36
LEU A 144
LEU A  26
PHE A 136
 None
 1.24A 3nk2X-4az3A:
undetectable		 3nk2X-4az3A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 MET A 756
LEU A 752
LEU A 556
PHE A 574
 None
 1.32A 3nk2X-4bziA:
undetectable		 3nk2X-4bziA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmr GLYCOSYL
HYDROLASE/DEACETYLAS
E FAMILY PROTEIN

(Pyrococcus sp.
ST04) 		no annotation 4 TYR A  95
LEU A 254
LEU A  84
PHE A 140
 None
 1.10A 3nk2X-4cmrA:
undetectable		 3nk2X-4cmrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2s UREIDOGLYCINE
AMINOHYDROLASE

(Arabidopsis
thaliana) 		PF07883
(Cupin_2) 		4 MET A 269
LEU A 254
LEU A 289
TRP A 268
 UGY  A 302 (-3.6A)
None
UGY  A 302 ( 4.9A)
None
 1.29A 3nk2X-4e2sA:
undetectable		 3nk2X-4e2sA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0g SERINE/THREONINE-PRO
TEIN KINASE ROCO4

(Dictyostelium
discoideum) 		PF07714
(Pkinase_Tyr) 		4 MET A1143
LEU A1085
LEU A1155
PHE A1282
 None
 1.28A 3nk2X-4f0gA:
undetectable		 3nk2X-4f0gA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 TYR A  66
ASN A 168
LEU A 393
LEU A  65
 None
 1.30A 3nk2X-4f4cA:
undetectable		 3nk2X-4f4cA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f5x RNA-DIRECTED RNA
POLYMERASE

(Rotavirus A) 		PF02123
(RdRP_4)
PF12289
(Rotavirus_VP1) 		4 ASN W 421
MET W 422
LEU W 408
LEU W 839
 None
 1.28A 3nk2X-4f5xW:
undetectable		 3nk2X-4f5xW:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2c DYP2

(Amycolatopsis
sp. ATCC 39116) 		no annotation 4 TYR A  87
MET A 379
LEU A 142
PHE A 381
 None
 1.09A 3nk2X-4g2cA:
undetectable		 3nk2X-4g2cA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gaa MGC78867 PROTEIN

(Xenopus laevis) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 MET A 517
LEU A 523
LEU A 509
PHE A 483
 None
 1.31A 3nk2X-4gaaA:
undetectable		 3nk2X-4gaaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iit PHENYLACETATE-COA
OXYGENASE SUBUNIT
PAAC

(Klebsiella
pneumoniae) 		PF05138
(PaaA_PaaC) 		4 TYR C 111
LEU C 182
LEU C 110
PHE C  55
 None
 1.29A 3nk2X-4iitC:
undetectable		 3nk2X-4iitC:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isa UDP-3-O-[3-HYDROXYMY
RISTOYL]
N-ACETYLGLUCOSAMINE
DEACETYLASE

(Escherichia
coli) 		PF03331
(LpxC) 		4 ASN A  81
MET A 249
LEU A 272
LEU A  66
 None
 1.07A 3nk2X-4isaA:
undetectable		 3nk2X-4isaA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mdp BETA-GLUCOSIDASE

(Humicola grisea) 		PF00232
(Glyco_hydro_1) 		4 TYR A 179
LEU A 326
LEU A 173
PHE A 348
 BGC  A 501 ( 4.1A)
None
BGC  A 501 ( 4.9A)
BGC  A 501 (-4.7A)
 1.17A 3nk2X-4mdpA:
undetectable		 3nk2X-4mdpA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nh0 CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 TYR A 545
MET A 552
LEU A 587
LEU A 607
 None
 1.25A 3nk2X-4nh0A:
undetectable		 3nk2X-4nh0A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qed ELXO

(Staphylococcus
epidermidis) 		PF13561
(adh_short_C2) 		4 TYR A  57
ASN A   5
LEU A  24
PHE A  78
 None
 0.98A 3nk2X-4qedA:
3.4		 3nk2X-4qedA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 TYR A 747
ASN A 719
LEU A 730
TRP A 712
 None
 1.23A 3nk2X-4qmeA:
undetectable		 3nk2X-4qmeA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt6 PROBABLE E3
UBIQUITIN-PROTEIN
LIGASE HERC1

(Homo sapiens) 		PF00622
(SPRY) 		4 TYR A2170
LEU A2110
LEU A2062
TRP A2109
 None
 1.32A 3nk2X-4qt6A:
undetectable		 3nk2X-4qt6A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upe NICKEL-DEPENDENT
HYDROGENASE LARGE
SUBUNIT

(Desulfovibrio
fructosivorans) 		PF00374
(NiFeSe_Hases) 		4 TYR Q 376
LEU Q 479
LEU Q 290
TRP Q 482
 None
FCO  Q1550 (-3.4A)
None
None
 1.11A 3nk2X-4upeQ:
undetectable		 3nk2X-4upeQ:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN

(Bacillus
anthracis) 		PF01522
(Polysacc_deac_1) 		4 MET A 261
LEU A 288
LEU A 245
PHE A 259
 None
 1.27A 3nk2X-4v33A:
undetectable		 3nk2X-4v33A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wx6 PROTEASE

(Human
mastadenovirus
D) 		PF00770
(Peptidase_C5) 		4 MET A 128
LEU A 178
LEU A 150
PHE A  70
 None
 1.18A 3nk2X-4wx6A:
undetectable		 3nk2X-4wx6A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 TYR A 478
LEU A 479
PHE A 391
TRP A 471
 None
 1.03A 3nk2X-4wz9A:
undetectable		 3nk2X-4wz9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csc CITRATE SYNTHASE

(Gallus gallus) 		PF00285
(Citrate_synt) 		4 TYR B 392
MET B 228
LEU B 396
PHE B 213
 None
 1.29A 3nk2X-5cscB:
undetectable		 3nk2X-5cscB:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw7 GLUCOSIDASE YGJK

(Escherichia
coli) 		PF01204
(Trehalase) 		4 MET A 652
LEU A 708
LEU A 635
PHE A 602
 None
 1.24A 3nk2X-5gw7A:
undetectable		 3nk2X-5gw7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzl LMO2445 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 TYR B 121
LEU B 172
LEU B 124
PHE B 116
 None
 1.22A 3nk2X-5hzlB:
undetectable		 3nk2X-5hzlB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6r SLIT-ROBO RHO
GTPASE-ACTIVATING
PROTEIN 2

(Homo sapiens) 		PF00611
(FCH) 		4 TYR A  17
ASN A 261
LEU A 254
LEU A 160
 None
 1.23A 3nk2X-5i6rA:
undetectable		 3nk2X-5i6rA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxu DYP-TYPE PEROXIDASE
FAMILY

(Thermomonospora
curvata) 		PF04261
(Dyp_perox) 		4 TYR A 351
LEU A 163
LEU A 251
PHE A  70
 None
 1.28A 3nk2X-5jxuA:
undetectable		 3nk2X-5jxuA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3

(Saccharomyces
cerevisiae) 		no annotation 4 ASN D 114
LEU D 136
LEU D 226
PHE D 110
 None
 1.24A 3nk2X-5m0jD:
undetectable		 3nk2X-5m0jD:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5x DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA135

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF06883
(RNA_pol_Rpa2_4) 		4 MET B 762
LEU B 703
LEU B  38
PHE B 765
 None
 1.32A 3nk2X-5m5xB:
undetectable		 3nk2X-5m5xB:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 TYR B 327
MET B 404
LEU B 401
LEU B 329
 None
 1.28A 3nk2X-5nd1B:
undetectable		 3nk2X-5nd1B:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nws SAACMM

(Streptomyces
antibioticus) 		no annotation 4 TYR A 175
ASN A 278
LEU A 396
LEU A 170
 None
 1.23A 3nk2X-5nwsA:
undetectable		 3nk2X-5nwsA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogl UNDECAPRENYL-DIPHOSP
HOOLIGOSACCHARIDE--P
ROTEIN
GLYCOTRANSFERASE

(Campylobacter
lari) 		no annotation 4 TYR A 393
ASN A  11
LEU A  19
LEU A 127
 None
 1.22A 3nk2X-5oglA:
undetectable		 3nk2X-5oglA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve6 TYROSINE-PROTEIN
KINASE SGK223

(Homo sapiens) 		no annotation 4 ASN A1046
LEU A1125
LEU A1383
PHE A1045
 None
 0.97A 3nk2X-5ve6A:
undetectable		 3nk2X-5ve6A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vsl RADICAL S-ADENOSYL
METHIONINE
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF04055
(Radical_SAM)
PF13353
(Fer4_12) 		4 MET A 309
LEU A 101
LEU A 113
PHE A 311
 None
 1.22A 3nk2X-5vslA:
undetectable		 3nk2X-5vslA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w57 PERIPLASMIC SOLUTE
BINDING PROTEIN

(Paracoccus
denitrificans) 		PF01297
(ZnuA) 		4 TYR A 149
LEU A  50
LEU A 106
PHE A  33
 None
 1.21A 3nk2X-5w57A:
undetectable		 3nk2X-5w57A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwy A TYPE VI-A
CRISPR-CAS
RNA-GUIDED RNA
RIBONUCLEASE, CAS13A

(Leptotrichia
buccalis) 		no annotation 4 ASN A 598
LEU A 701
LEU A 520
PHE A 543
 None
 1.07A 3nk2X-5xwyA:
undetectable		 3nk2X-5xwyA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yjp HUMAN CHYMASE

(Homo sapiens) 		no annotation 4 MET A  30
LEU A 155
LEU A 200
PHE A  45
 None
 1.21A 3nk2X-5yjpA:
undetectable		 3nk2X-5yjpA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo sapiens) 		no annotation 4 ASN A1386
LEU A1496
LEU A1723
PHE A1385
 None
 0.96A 3nk2X-6bhcA:
undetectable		 3nk2X-6bhcA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c87 RAB GDP DISSOCIATION
INHIBITOR ALPHA

(Naegleria
fowleri) 		no annotation 4 TYR A 385
MET A  51
LEU A  48
LEU A  76
 None
 1.28A 3nk2X-6c87A:
14.8		 3nk2X-6c87A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ckb -

(-) 		no annotation 4 TYR A 148
LEU A 178
LEU A 114
PHE A 281
 None
 1.29A 3nk2X-6ckbA:
undetectable		 3nk2X-6ckbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eot DIPEPTIDYL PEPTIDASE
8

(Homo sapiens) 		no annotation 4 TYR A 759
ASN A 704
LEU A 676
LEU A 760
 None
 1.24A 3nk2X-6eotA:
undetectable		 3nk2X-6eotA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ewx PEAK1-RELATED
KINASE-ACTIVATING
PSEUDOKINASE 1

(Rattus
norvegicus) 		no annotation 4 ASN A1019
LEU A1099
LEU A1345
PHE A1018
 None
 0.94A 3nk2X-6ewxA:
undetectable		 3nk2X-6ewxA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 4 MET A 650
LEU A 669
LEU A 674
PHE A 647
 None
 1.26A 3nk2X-6f8zA:
undetectable		 3nk2X-6f8zA:
11.44