SIMILAR PATTERNS OF AMINO ACIDS FOR 3NBQ_B_URFB400_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bf5 SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind) 		4 GLY A 523
LEU A 526
LEU A 527
ILE A 537
 None
 0.82A 3nbqB-1bf5A:
0.0		 3nbqB-1bf5A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6z CHITINASE B

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18) 		4 GLY A 138
LEU A 181
LEU A 165
ILE A 161
 None
 0.91A 3nbqB-1e6zA:
0.0		 3nbqB-1e6zA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g31 GP31

(Escherichia
virus T4) 		PF00166
(Cpn10) 		4 THR A  69
GLN A  24
LEU A  71
ILE A  76
 None
 0.81A 3nbqB-1g31A:
undetectable		 3nbqB-1g31A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gns SUBTILISIN BPN'

(Bacillus
amyloliquefaciens) 		PF00082
(Peptidase_S8) 		4 GLY A  70
MET A 222
LEU A  42
ILE A  35
 None
CSO  A 221 ( 3.8A)
None
None
 0.95A 3nbqB-1gnsA:
2.6		 3nbqB-1gnsA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta) 		PF01804
(Penicil_amidase) 		4 THR A 218
GLY A 216
GLN A 189
ILE A 326
 None
 0.91A 3nbqB-1kehA:
0.0		 3nbqB-1kehA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kyh HYPOTHETICAL 29.9
KDA PROTEIN IN
SIGY-CYDD INTERGENIC
REGION

(Bacillus
subtilis) 		PF01256
(Carb_kinase) 		4 THR A 217
GLY A  47
LEU A  45
LEU A  44
 None
 0.87A 3nbqB-1kyhA:
0.0		 3nbqB-1kyhA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2q MONOMETHYLAMINE
METHYLTRANSFERASE

(Methanosarcina
barkeri) 		PF05369
(MtmB) 		4 GLY A  74
LEU A  71
LEU A  70
ILE A  91
 None
 0.82A 3nbqB-1l2qA:
0.0		 3nbqB-1l2qA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lcy HTRA2 SERINE
PROTEASE

(Homo sapiens) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 GLY A 273
ARG A 310
LEU A 317
ILE A 308
 None
 0.84A 3nbqB-1lcyA:
undetectable		 3nbqB-1lcyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1now BETA-HEXOSAMINIDASE
BETA CHAIN

(Homo sapiens) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2) 		4 GLY A 299
LEU A 305
LEU A 306
ILE A 322
 None
 0.90A 3nbqB-1nowA:
0.9		 3nbqB-1nowA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgu PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)

(Klebsiella
pneumoniae) 		PF00148
(Oxidored_nitro) 		4 THR A 148
GLY A 146
LEU A 257
ILE A 205
 None
 0.91A 3nbqB-1qguA:
3.2		 3nbqB-1qguA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qle CYTOCHROME C OXIDASE
POLYPEPTIDE III

(Paracoccus
denitrificans) 		PF00510
(COX3) 		4 GLY C 237
LEU C 235
LEU C 234
ILE C 172
 None
 0.91A 3nbqB-1qleC:
undetectable		 3nbqB-1qleC:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szi MANNOSE-6-PHOSPHATE
RECEPTOR BINDING
PROTEIN 1

(Mus musculus) 		PF03036
(Perilipin) 		4 THR A 338
LEU A 276
LEU A 273
ILE A 398
 None
 0.95A 3nbqB-1sziA:
undetectable		 3nbqB-1sziA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 GLY A 597
LEU A 459
LEU A 456
ILE A 546
 None
 0.76A 3nbqB-1taqA:
undetectable		 3nbqB-1taqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vz8 ORNITHINE
ACETYL-TRANSFERASE

(Streptomyces
clavuligerus) 		PF01960
(ArgJ) 		4 THR A 184
GLY A 171
LEU A 182
LEU A 175
 None
SO4  A1391 ( 4.6A)
None
None
 0.94A 3nbqB-1vz8A:
undetectable		 3nbqB-1vz8A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Pyrococcus
abyssi) 		PF00710
(Asparaginase) 		4 THR A 342
GLY A 340
LEU A 382
LEU A 373
 None
 0.72A 3nbqB-1zq1A:
1.7		 3nbqB-1zq1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa) 		PF02274
(Amidinotransf) 		4 GLY A 239
MET A 229
LEU A 270
ILE A 301
 None
 0.86A 3nbqB-2aafA:
undetectable		 3nbqB-2aafA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE

(Pseudomonas sp.
SY-77-1) 		PF01804
(Penicil_amidase) 		4 THR C  49
GLY C  47
GLN B  20
ILE C 157
 None
 0.95A 3nbqB-2advC:
undetectable		 3nbqB-2advC:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4n DU

(Mason-Pfizer
monkey virus) 		PF00692
(dUTPase) 		4 THR A 154
GLY A 156
LEU A 206
ILE A 110
 None
 0.88A 3nbqB-2d4nA:
undetectable		 3nbqB-2d4nA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2db3 ATP-DEPENDENT RNA
HELICASE VASA

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 GLY A 377
LEU A 379
LEU A 380
ILE A 416
 U  E   6 ( 3.2A)
None
None
None
 0.89A 3nbqB-2db3A:
undetectable		 3nbqB-2db3A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ecf DIPEPTIDYL PEPTIDASE
IV

(Stenotrophomonas
maltophilia) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 GLY A 589
GLN A 586
LEU A 593
ILE A 604
 None
 0.81A 3nbqB-2ecfA:
undetectable		 3nbqB-2ecfA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpv MAJOR FIMBRIAL
SUBUNIT OF
AGGREGATIVE
ADHERENCE FIMBRIA II
AAFA

(Escherichia
coli) 		no annotation 4 GLY A  58
GLN A  64
LEU A 130
ILE A  41
 None
 0.71A 3nbqB-2mpvA:
undetectable		 3nbqB-2mpvA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pzd SERINE PROTEASE
HTRA2

(Homo sapiens) 		PF13180
(PDZ_2) 		4 GLY A 406
ARG A 443
LEU A 450
ILE A 441
 None
 0.87A 3nbqB-2pzdA:
undetectable		 3nbqB-2pzdA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfn ALPHA-GALACTOSIDASE-
SUCROSE KINASE AGASK

([Ruminococcus]
gnavus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 GLY A 303
LEU A 307
LEU A 304
ILE A 233
 None
 0.90A 3nbqB-2yfnA:
undetectable		 3nbqB-2yfnA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abi PUTATIVE
UNCHARACTERIZED
PROTEIN PH1688

(Pyrococcus
horikoshii) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 GLY A 275
LEU A 136
LEU A 134
ILE A 130
 None
 0.81A 3nbqB-3abiA:
undetectable		 3nbqB-3abiA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq1 THERMOSOME SUBUNIT

(Methanococcoides
burtonii) 		PF00118
(Cpn60_TCP1) 		4 GLY B 467
GLN B 458
LEU B 468
ILE B 451
 None
 0.87A 3nbqB-3aq1B:
undetectable		 3nbqB-3aq1B:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1r RIBOKINASE, PUTATIVE

(Burkholderia
thailandensis) 		PF00294
(PfkB) 		4 GLY A 257
LEU A 259
LEU A 260
ILE A 164
 None
 0.75A 3nbqB-3b1rA:
undetectable		 3nbqB-3b1rA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bje NUCLEOSIDE
PHOSPHORYLASE,
PUTATIVE

(Trypanosoma
brucei) 		PF01048
(PNP_UDP_1) 		5 THR A 140
GLY A 142
GLN A 246
ARG A 248
MET A 285
 R1P  A 401 (-3.0A)
URA  A 501 (-3.4A)
URA  A 501 (-3.0A)
URA  A 501 (-2.9A)
R1P  A 401 ( 3.9A)
 0.26A 3nbqB-3bjeA:
23.4		 3nbqB-3bjeA:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Mus musculus) 		PF00004
(AAA)
PF09336
(Vps4_C) 		4 THR A 623
GLY A 621
LEU A 639
ILE A 633
 None
 0.65A 3nbqB-3cf0A:
undetectable		 3nbqB-3cf0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0k AMINO-ACID
ACETYLTRANSFERASE

(Vibrio
parahaemolyticus) 		PF00583
(Acetyltransf_1) 		4 GLY A 381
LEU A 383
LEU A 384
ILE A 343
 SO4  A 501 (-3.8A)
None
None
None
 0.95A 3nbqB-3e0kA:
undetectable		 3nbqB-3e0kA:
17.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3euf URIDINE
PHOSPHORYLASE 1

(Homo sapiens) 		PF01048
(PNP_UDP_1) 		7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.23A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3euf URIDINE
PHOSPHORYLASE 1

(Homo sapiens) 		PF01048
(PNP_UDP_1) 		5 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.76A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hng VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 GLY A1155
LEU A1157
LEU A1158
ILE A1000
 None
 0.85A 3nbqB-3hngA:
undetectable		 3nbqB-3hngA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 GLY A 293
LEU A 369
LEU A 373
ILE A 170
 None
 0.94A 3nbqB-3hrdA:
undetectable		 3nbqB-3hrdA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icu E3 UBIQUITIN-PROTEIN
LIGASE RNF128

(Homo sapiens) 		PF02225
(PA) 		4 GLY A  69
MET A 158
LEU A  47
ILE A 193
 None
 0.80A 3nbqB-3icuA:
undetectable		 3nbqB-3icuA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3id3 REGULATOR OF SIGMA E
PROTEASE

(Escherichia
coli) 		PF00595
(PDZ) 		4 GLY A 239
ARG A 278
LEU A 285
ILE A 276
 None
 0.83A 3nbqB-3id3A:
undetectable		 3nbqB-3id3A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu6 PROTEIN POLYBROMO-1

(Homo sapiens) 		PF00439
(Bromodomain) 		4 GLY A 851
LEU A 749
LEU A 745
ILE A 746
 None
 0.88A 3nbqB-3iu6A:
undetectable		 3nbqB-3iu6A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jac PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		PF12166
(Piezo_RRas_bdg) 		4 GLY A2360
ARG A2301
LEU A2357
LEU A2405
 None
 0.91A 3nbqB-3jacA:
undetectable		 3nbqB-3jacA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kvy URIDINE
PHOSPHORYLASE

(Bos taurus) 		PF01048
(PNP_UDP_1) 		8 THR A 140
GLY A 142
GLN A 216
ARG A 218
MET A 248
LEU A 271
LEU A 272
ILE A 280
 SO4  A 311 ( 3.1A)
URA  A 312 (-3.3A)
URA  A 312 (-3.3A)
URA  A 312 (-2.9A)
URA  A 312 ( 3.7A)
None
None
None
 0.21A 3nbqB-3kvyA:
46.4		 3nbqB-3kvyA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p0f URIDINE
PHOSPHORYLASE 2

(Homo sapiens) 		PF01048
(PNP_UDP_1) 		7 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.34A 3nbqB-3p0fA:
44.1		 3nbqB-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p0f URIDINE
PHOSPHORYLASE 2

(Homo sapiens) 		PF01048
(PNP_UDP_1) 		5 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.65A 3nbqB-3p0fA:
44.1		 3nbqB-3p0fA:
62.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		4 THR A 223
GLY A 381
LEU A 452
ILE A 449
 None
 0.92A 3nbqB-3pf2A:
undetectable		 3nbqB-3pf2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pie 5'->3'
EXORIBONUCLEASE
(XRN1)

(Kluyveromyces
lactis) 		PF03159
(XRN_N) 		4 GLN A  16
LEU A 744
LEU A 746
ILE A 771
 None
 0.72A 3nbqB-3pieA:
undetectable		 3nbqB-3pieA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3puk SYNTAXIN-BINDING
PROTEIN 3

(Mus musculus) 		PF00995
(Sec1) 		4 THR A 247
LEU A 573
LEU A 574
ILE A 577
 None
 0.94A 3nbqB-3pukA:
undetectable		 3nbqB-3pukA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r8x METHIONYL-TRNA
FORMYLTRANSFERASE

(Yersinia pestis) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 GLY A  21
LEU A  23
LEU A  24
ILE A  30
 None
 0.87A 3nbqB-3r8xA:
undetectable		 3nbqB-3r8xA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqw ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 GLY A 560
LEU A 562
LEU A 563
ILE A 526
 None
 0.88A 3nbqB-3sqwA:
undetectable		 3nbqB-3sqwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1

(Bos taurus) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase) 		4 GLY A  17
GLN A  28
LEU A  13
ILE A 222
 None
 0.85A 3nbqB-3tlmA:
undetectable		 3nbqB-3tlmA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v48 PUTATIVE
AMINOACRYLATE
HYDROLASE RUTD

(Escherichia
coli) 		PF00561
(Abhydrolase_1) 		4 GLY A  90
GLN A  47
LEU A  92
ILE A  63
 None
 0.81A 3nbqB-3v48A:
undetectable		 3nbqB-3v48A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 GLN A1885
LEU A1859
LEU A1856
ILE A1879
 None
 0.90A 3nbqB-3vkgA:
undetectable		 3nbqB-3vkgA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsk PENICILLIN-BINDING
PROTEIN 3

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 GLN A 170
LEU A 182
LEU A 179
ILE A 120
 None
 0.87A 3nbqB-3vskA:
undetectable		 3nbqB-3vskA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		4 GLY A 405
LEU A 414
LEU A 415
ILE A 313
 None
 0.91A 3nbqB-3zxsA:
undetectable		 3nbqB-3zxsA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab5 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF03466
(LysR_substrate) 		4 GLY A 138
LEU A 140
LEU A 141
ILE A 159
 None
 0.79A 3nbqB-4ab5A:
undetectable		 3nbqB-4ab5A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3k BETA-GLUCOSIDASE

(Streptococcus
pyogenes) 		PF00232
(Glyco_hydro_1) 		4 THR A 221
GLY A 295
LEU A 223
LEU A 296
 None
 0.91A 3nbqB-4b3kA:
undetectable		 3nbqB-4b3kA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db4 ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00271
(Helicase_C) 		4 GLY A 560
LEU A 562
LEU A 563
ILE A 526
 None
 0.85A 3nbqB-4db4A:
undetectable		 3nbqB-4db4A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyu DNA PROTECTION
DURING STARVATION
PROTEIN

(Yersinia pestis) 		PF00210
(Ferritin) 		4 THR A  47
LEU A 121
LEU A 118
ILE A 162
 None
 0.90A 3nbqB-4dyuA:
undetectable		 3nbqB-4dyuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Xanthomonas
campestris) 		PF00563
(EAL) 		4 GLY A 120
GLN A  86
LEU A 116
ILE A  79
 None
 0.88A 3nbqB-4f48A:
undetectable		 3nbqB-4f48A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxd DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 THR A1004
MET A 988
LEU A 861
ILE A1034
 None
 0.95A 3nbqB-4fxdA:
undetectable		 3nbqB-4fxdA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4go4 PUTATIVE
GAMMA-HYDROXYMUCONIC
SEMIALDEHYDE
DEHYDROGENASE

(Pseudomonas sp.
WBC-3) 		PF00171
(Aldedh) 		4 GLY A 448
MET A 459
LEU A 409
ILE A 282
 None
None
NAD  A 601 (-4.3A)
None
 0.83A 3nbqB-4go4A:
undetectable		 3nbqB-4go4A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gvl TRKA DOMAIN PROTEIN

(Geobacter
sulfurreducens) 		PF02080
(TrkA_C)
PF02254
(TrkA_N) 		4 GLY A 474
LEU A 476
LEU A 477
ILE A 224
 None
 0.84A 3nbqB-4gvlA:
undetectable		 3nbqB-4gvlA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h27 L-SERINE
DEHYDRATASE/L-THREON
INE DEAMINASE

(Homo sapiens) 		PF00291
(PALP) 		4 GLY A 161
LEU A 298
LEU A 295
ILE A 282
 None
 0.92A 3nbqB-4h27A:
undetectable		 3nbqB-4h27A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h8n CONJUGATED
POLYKETONE REDUCTASE
C2

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		4 THR A  59
GLY A  24
LEU A  23
ILE A  46
 None
NDP  A3001 (-3.4A)
None
None
 0.85A 3nbqB-4h8nA:
undetectable		 3nbqB-4h8nA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6m ACTIN-LIKE PROTEIN
ARP9

(Saccharomyces
cerevisiae) 		PF00022
(Actin) 		4 GLY B 351
LEU B 353
LEU B 354
ILE B 407
 None
 0.91A 3nbqB-4i6mB:
undetectable		 3nbqB-4i6mB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kcd GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 3A

(Rattus
norvegicus) 		PF10613
(Lig_chan-Glu_bd) 		4 GLY A 110
LEU A 112
LEU A 113
ILE A 134
 None
 0.86A 3nbqB-4kcdA:
undetectable		 3nbqB-4kcdA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6r ALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 GLY A 449
MET A 460
LEU A 410
ILE A 282
 None
None
None
NO3  A 502 (-4.8A)
 0.65A 3nbqB-4o6rA:
undetectable		 3nbqB-4o6rA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 THR A 323
GLY A 334
LEU A 364
ILE A 354
 None
 0.86A 3nbqB-4q0gA:
undetectable		 3nbqB-4q0gA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2w URIDINE
PHOSPHORYLASE

(Shewanella
oneidensis) 		PF01048
(PNP_UDP_1) 		5 THR A  91
GLY A  93
GLN A 163
ARG A 165
MET A 194
 SO4  A 302 ( 3.0A)
None
None
None
GOL  A 303 (-3.5A)
 0.36A 3nbqB-4r2wA:
25.6		 3nbqB-4r2wA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rax PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		PF12166
(Piezo_RRas_bdg) 		4 GLY A2360
ARG A2301
LEU A2357
LEU A2405
 None
 0.90A 3nbqB-4raxA:
undetectable		 3nbqB-4raxA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 GLY A1877
LEU A1879
LEU A1880
ILE A1897
 None
 0.80A 3nbqB-4rh7A:
undetectable		 3nbqB-4rh7A:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzz PEPTIDASE M24

(Ruegeria
lacuscaerulensis) 		PF00557
(Peptidase_M24) 		4 THR A  64
GLY A  74
LEU A 106
LEU A 105
 None
 0.76A 3nbqB-4rzzA:
undetectable		 3nbqB-4rzzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz0 ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 GLY A 560
LEU A 562
LEU A 563
ILE A 526
 None
 0.90A 3nbqB-4tz0A:
undetectable		 3nbqB-4tz0A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wan BRANCHPOINT-BRIDGING
PROTEIN

(Saccharomyces
cerevisiae) 		PF00013
(KH_1) 		4 GLY A 166
LEU A 168
LEU A 169
ILE A 189
 U  B   6 ( 3.7A)
None
A  B   7 ( 3.8A)
A  B   8 ( 4.2A)
 0.85A 3nbqB-4wanA:
undetectable		 3nbqB-4wanA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x4w CCA TRNA
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF01743
(PolyA_pol)
PF12627
(PolyA_pol_RNAbd) 		4 GLY A 379
LEU A 381
LEU A 382
ILE A 367
 None
 0.92A 3nbqB-4x4wA:
undetectable		 3nbqB-4x4wA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xtl SODIUM PUMPING
RHODOPSIN

(Dokdonia
eikasta) 		PF01036
(Bac_rhodopsin) 		4 GLY A 259
LEU A 261
LEU A 262
ILE A 207
 LYR  A 255 ( 3.6A)
None
None
None
 0.88A 3nbqB-4xtlA:
undetectable		 3nbqB-4xtlA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye9 GLUTAMINE--TRNA
LIGASE

(Homo sapiens) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
PF04557
(tRNA_synt_1c_R2)
PF04558
(tRNA_synt_1c_R1) 		4 GLY A  53
LEU A  55
LEU A  56
ILE A  76
 None
 0.88A 3nbqB-4ye9A:
undetectable		 3nbqB-4ye9A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywo MERCURIC REDUCTASE

(Metallosphaera
sedula) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 THR A 130
GLY A 291
LEU A 294
ILE A 274
 FAD  A 501 (-3.8A)
FAD  A 501 (-3.3A)
GOL  A 506 (-4.2A)
None
 0.90A 3nbqB-4ywoA:
undetectable		 3nbqB-4ywoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwn MONOGLYCERIDE LIPASE

(Saccharomyces
cerevisiae) 		PF12146
(Hydrolase_4) 		4 GLY A 200
LEU A 184
LEU A 186
ILE A 189
 None
 0.93A 3nbqB-4zwnA:
2.3		 3nbqB-4zwnA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6b N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
pneumoniae) 		PF00728
(Glyco_hydro_20) 		4 GLY D 563
LEU D 565
LEU D 566
ILE D 535
 None
 0.86A 3nbqB-5a6bD:
undetectable		 3nbqB-5a6bD:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1b TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Homo sapiens) 		PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
PF09336
(Vps4_C) 		4 THR A 623
GLY A 621
LEU A 639
ILE A 633
 None
 0.68A 3nbqB-5c1bA:
undetectable		 3nbqB-5c1bA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2i ALR1585 PROTEIN

(Nostoc sp. PCC
7120) 		PF04261
(Dyp_perox) 		4 GLY A 423
GLN A 402
LEU A 447
ILE A 449
 None
HEM  A 501 (-4.4A)
None
HEM  A 501 (-4.1A)
 0.89A 3nbqB-5c2iA:
undetectable		 3nbqB-5c2iA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK

(Escherichia
coli) 		PF00589
(Phage_integrase)
PF09397
(Ftsk_gamma) 		4 GLY A 149
ARG A 177
LEU A 146
LEU A 145
 None
 0.93A 3nbqB-5dcfA:
undetectable		 3nbqB-5dcfA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej1 PUTATIVE CELLULOSE
SYNTHASE

(Rhodobacter
sphaeroides) 		PF00535
(Glycos_transf_2)
PF03170
(BcsB)
PF03552
(Cellulose_synt)
PF07238
(PilZ) 		4 GLY B 700
LEU B 698
LEU B 697
ILE A  45
 None
 0.90A 3nbqB-5ej1B:
undetectable		 3nbqB-5ej1B:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY

(Bacillus cereus) 		PF06018
(CodY)
PF08222
(HTH_CodY) 		4 GLN A 133
ARG A 130
LEU A 142
ILE A  35
 None
 0.92A 3nbqB-5ey2A:
undetectable		 3nbqB-5ey2A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f59 HISTONE-LYSINE
N-METHYLTRANSFERASE
2C

(Homo sapiens) 		PF00856
(SET) 		4 MET A4765
LEU A4882
LEU A4785
ILE A4847
 None
 0.95A 3nbqB-5f59A:
undetectable		 3nbqB-5f59A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibz UNCHARACTERIZED
PROTEIN

(uncultured
organism) 		PF04199
(Cyclase) 		4 GLY A 287
LEU A 289
LEU A 290
ILE A 297
 None
 0.79A 3nbqB-5ibzA:
undetectable		 3nbqB-5ibzA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5imu TAT (TWIN-ARGININE
TRANSLOCATION)
PATHWAY SIGNAL
SEQUENCE CONTAINING
PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 4 GLY A 348
LEU A 346
LEU A 345
ILE A 324
 None
 0.83A 3nbqB-5imuA:
undetectable		 3nbqB-5imuA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lhv URIDINE
PHOSPHORYLASE

(Vibrio cholerae) 		PF01048
(PNP_UDP_1) 		5 THR A  93
GLY A  95
GLN A 165
ARG A 167
MET A 196
 SO4  A 301 ( 2.9A)
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
 0.33A 3nbqB-5lhvA:
26.0		 3nbqB-5lhvA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tul TETRACYCLINE
DESTRUCTASE TET(55)

(uncultured
bacterium) 		PF01494
(FAD_binding_3) 		4 THR A 293
GLY A 157
ARG A  40
LEU A 158
 None
PO4  A 401 (-3.5A)
None
None
 0.91A 3nbqB-5tulA:
undetectable		 3nbqB-5tulA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u70 POTASSIUM CHANNEL
SUBFAMILY T MEMBER 1

(Gallus gallus) 		PF03493
(BK_channel_a)
PF07885
(Ion_trans_2) 		4 THR A 507
LEU A 511
LEU A 512
ILE A1148
 None
 0.92A 3nbqB-5u70A:
undetectable		 3nbqB-5u70A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA

(Rickettsia
conorii) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 THR A   8
LEU A  87
LEU A  89
ILE A  99
 None
 0.80A 3nbqB-5w7zA:
undetectable		 3nbqB-5w7zA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy4 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 GLY A 252
MET A 259
LEU A 248
ILE A 288
 None
 0.82A 3nbqB-5wy4A:
undetectable		 3nbqB-5wy4A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x59 S PROTEIN

(Middle East
respiratory
syndrome-related
coronavirus) 		PF01601
(Corona_S2)
PF09408
(Spike_rec_bind) 		4 THR A 986
GLY A 982
LEU A 980
ILE A1123
 None
 0.86A 3nbqB-5x59A:
undetectable		 3nbqB-5x59A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x62 CARNOSINE
N-METHYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF07942
(N2227) 		4 GLY A 150
LEU A 152
LEU A 153
ILE A 144
 None
 0.83A 3nbqB-5x62A:
undetectable		 3nbqB-5x62A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6o SERINE/THREONINE-PRO
TEIN KINASE MEC1

(Saccharomyces
cerevisiae) 		no annotation 4 GLY C1096
LEU C1098
LEU C1099
ILE C1120
 None
 0.90A 3nbqB-5x6oC:
undetectable		 3nbqB-5x6oC:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5znn SORTILIN

(Mus musculus) 		no annotation 4 THR A 428
GLY A 410
LEU A 634
ILE A 716
 None
 0.84A 3nbqB-5znnA:
undetectable		 3nbqB-5znnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		no annotation 4 THR A 826
GLN A 774
LEU A 824
ILE A 811
 None
 0.81A 3nbqB-6bhuA:
undetectable		 3nbqB-6bhuA:
0.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cc4 SOLUBLE CYTOCHROME
B562, LIPID II
FLIPPASE MURJ
CHIMERA

(Escherichia
coli) 		no annotation 4 GLY A 457
LEU A 459
LEU A 460
ILE A 327
 None
 0.86A 3nbqB-6cc4A:
undetectable		 3nbqB-6cc4A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6crj NORWALK VIRUS, MNV-1
CAPSID PROTEIN
CHIMERA

(Norwalk virus) 		no annotation 4 THR B 119
GLY B 121
LEU B 190
ILE B  70
 None
 0.89A 3nbqB-6crjB:
undetectable		 3nbqB-6crjB:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d46 BETA SLIDING CLAMP

(Rickettsia
typhi) 		no annotation 4 THR A   8
LEU A  87
LEU A  89
ILE A  99
 None
 0.85A 3nbqB-6d46A:
undetectable		 3nbqB-6d46A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f71 GLUTATHIONE
TRANSFERASE

(Trametes
versicolor) 		no annotation 4 ARG A  20
LEU A 121
LEU A 122
ILE A 171
 None
 0.91A 3nbqB-6f71A:
undetectable		 3nbqB-6f71A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2

(Mus musculus) 		no annotation 4 GLY A 283
LEU A 335
LEU A 368
ILE A 364
 None
 0.87A 3nbqB-6fv5A:
undetectable		 3nbqB-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2

(Mus musculus) 		no annotation 4 GLY A 376
LEU A 378
LEU A 379
ILE A 364
 None
 0.82A 3nbqB-6fv5A:
undetectable		 3nbqB-6fv5A:
13.38