SIMILAR PATTERNS OF AMINO ACIDS FOR 3N9J_B_EAAB214
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b8x | PROTEIN (AML-1B) (Escherichiacoli) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 6GLY A 11TYR A 110GLY A 204 | None | 0.65A | 3n9jB-1b8xA:23.6 | 3n9jB-1b8xA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bud | PROTEIN (ACUTOLYSINA) (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 4 | VAL A 150ARG A 187ILE A 49TYR A 44 | None | 0.82A | 3n9jB-1budA:undetectable | 3n9jB-1budA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e7n | BETA-CRYSTALLIN B2 (Mus musculus) |
PF00030(Crystall) | 4 | TYR A 62VAL A 37GLY A 60GLY A 40 | None | 0.80A | 3n9jB-1e7nA:undetectable | 3n9jB-1e7nA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecg | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Escherichiacoli) |
PF00156(Pribosyltran)PF13522(GATase_6) | 4 | VAL A 12GLY A 8ILE A 232GLY A 68 | None | 0.73A | 3n9jB-1ecgA:undetectable | 3n9jB-1ecgA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhe | GLUTATHIONETRANSFERASE (Fasciolahepatica) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 6GLY A 11TYR A 110GLY A 204 | None | 0.69A | 3n9jB-1fheA:24.6 | 3n9jB-1fheA:29.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gsq | GLUTATHIONES-TRANSFERASE (Todarodespacificus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 7PHE A 8GLY A 12ARG A 13 | NoneGDN A 203 (-4.5A)NoneGDN A 203 (-4.9A) | 0.50A | 3n9jB-1gsqA:25.6 | 3n9jB-1gsqA:32.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 115PHE A 70ILE A 199GLY A 175 | None | 0.73A | 3n9jB-1kgpA:undetectable | 3n9jB-1kgpA:20.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbk | GLUTATHIONES-TRANSFERASE CLASSPI CHIMAERA (CODA) (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | TYR A 7GLY A 12ARG A 13ILE A 104TYR A 108 | NoneNoneGSH A 504 (-3.7A)NoneNone | 0.63A | 3n9jB-1lbkA:36.0 | 3n9jB-1lbkA:97.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbk | GLUTATHIONES-TRANSFERASE CLASSPI CHIMAERA (CODA) (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 6 | TYR A 7PHE A 8VAL A 10GLY A 12ARG A 13ILE A 104 | NoneGSH A 504 (-4.7A)NoneNoneGSH A 504 (-3.7A)None | 0.51A | 3n9jB-1lbkA:36.0 | 3n9jB-1lbkA:97.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m4y | ATP-DEPENDENTPROTEASE HSLV (Thermotogamaritima) |
PF00227(Proteasome) | 4 | VAL A 34GLY A 45ILE A 122GLY A 16 | None | 0.80A | 3n9jB-1m4yA:undetectable | 3n9jB-1m4yA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1omx | ALPHA-1,4-N-ACETYLHEXOSAMINYLTRANSFERASEEXTL2 (Mus musculus) |
PF09258(Glyco_transf_64) | 4 | TYR A 209VAL A 212GLY A 262GLY A 177 | None | 0.72A | 3n9jB-1omxA:undetectable | 3n9jB-1omxA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd2 | HEMATOPOIETICPROSTAGLANDIN DSYNTHASE (Rattusnorvegicus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR 1 8PHE 1 9GLY 1 13ARG 1 14 | GSH 1 301 (-4.8A)NoneNoneGSH 1 301 (-3.4A) | 0.53A | 3n9jB-1pd21:23.9 | 3n9jB-1pd21:28.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poj | ISOASPARTYLDIPEPTIDASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 4 | VAL A 152GLY A 189ARG A 186GLY A 160 | None | 0.64A | 3n9jB-1pojA:undetectable | 3n9jB-1pojA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz3 | ALPHA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF06964(Alpha-L-AF_C) | 4 | VAL A 413ILE A 23TYR A 24GLY A 383 | None | 0.78A | 3n9jB-1pz3A:undetectable | 3n9jB-1pz3A:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1n | HYPOTHETICALZINC-TYPE ALCOHOLDEHYDROGENASE-LIKEPROTEIN IN PRE5-FET4INTERGENIC REGION (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | VAL A 168GLY A 165ILE A 321GLY A 195 | None | 0.75A | 3n9jB-1q1nA:undetectable | 3n9jB-1q1nA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qlb | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Wolinellasuccinogenes) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | PHE A 424VAL A 420GLY A 381ILE A 375 | None | 0.77A | 3n9jB-1qlbA:undetectable | 3n9jB-1qlbA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE III (Paracoccusdenitrificans) |
PF00510(COX3) | 4 | PHE C 19VAL C 61GLY C 57GLY C 20 | None | 0.78A | 3n9jB-1qleC:undetectable | 3n9jB-1qleC:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 105PHE A 60ILE A 189GLY A 165 | None | 0.81A | 3n9jB-1r2fA:undetectable | 3n9jB-1r2fA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r5j | PUTATIVEPHOSPHOTRANSACETYLASE (Streptococcuspyogenes) |
PF01515(PTA_PTB) | 4 | VAL A 22GLY A 122ILE A 142GLY A 111 | None | 0.80A | 3n9jB-1r5jA:undetectable | 3n9jB-1r5jA:21.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tu7 | GLUTATHIONES-TRANSFERASE 2 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | TYR A 7PHE A 8GLY A 12TYR A 106GLY A 204 | NoneGSH A1001 (-4.8A)NoneNoneNone | 0.50A | 3n9jB-1tu7A:30.5 | 3n9jB-1tu7A:42.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tu7 | GLUTATHIONES-TRANSFERASE 2 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 106GLY A 204TYR A 7GLY A 12 | None | 0.75A | 3n9jB-1tu7A:30.5 | 3n9jB-1tu7A:42.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuo | PUTATIVEPHOSPHOMANNOMUTASE (Thermusthermophilus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | VAL A 95GLY A 103ILE A 128GLY A 125 | None | 0.81A | 3n9jB-1tuoA:undetectable | 3n9jB-1tuoA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3i | GLUTATHIONES-TRANSFERASE 28 KDA (Schistosomamansoni) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 10PHE A 11GLY A 15ARG A 16 | NoneNoneNoneGSH A 301 (-4.2A) | 0.75A | 3n9jB-1u3iA:23.5 | 3n9jB-1u3iA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 110PHE A 65ILE A 194GLY A 170 | None | 0.81A | 3n9jB-1uzrA:undetectable | 3n9jB-1uzrA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v40 | GLUTATHIONE-REQUIRING PROSTAGLANDIN DSYNTHASE (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 8PHE A 9GLY A 13ARG A 14 | NoneO16 A3201 (-3.0A)O16 A3201 ( 3.7A)O16 A3201 ( 3.8A) | 0.39A | 3n9jB-1v40A:24.4 | 3n9jB-1v40A:27.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xco | PHOSPHATEACETYLTRANSFERASE (Bacillussubtilis) |
PF01515(PTA_PTB) | 4 | VAL A 20GLY A 120ILE A 140GLY A 109 | None | 0.77A | 3n9jB-1xcoA:undetectable | 3n9jB-1xcoA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a18 | CARBON DIOXIDECONCENTRATINGMECHANISM PROTEINCCMK HOMOLOG 4 (Synechocystissp. PCC 6803) |
PF00936(BMC) | 4 | VAL A 55GLY A 8ILE A 93GLY A 50 | None | 0.81A | 3n9jB-2a18A:undetectable | 3n9jB-2a18A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dr3 | UPF0273 PROTEINPH0284 (Pyrococcushorikoshii) |
PF06745(ATPase) | 4 | VAL A 172GLY A 180ILE A 191GLY A 30 | None | 0.80A | 3n9jB-2dr3A:undetectable | 3n9jB-2dr3A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f7l | 455AA LONGHYPOTHETICALPHOSPHO-SUGAR MUTASE (Sulfurisphaeratokodaii) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | PHE A 133VAL A 64GLY A 60GLY A 31 | None | 0.72A | 3n9jB-2f7lA:undetectable | 3n9jB-2f7lA:19.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fhe | GLUTATHIONES-TRANSFERASE (Fasciolahepatica) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 6GLY A 11TYR A 110GLY A 204 | None | 0.54A | 3n9jB-2fheA:25.4 | 3n9jB-2fheA:31.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gsr | CLASS PI GSTGLUTATHIONES-TRANSFERASE (Sus scrofa) |
PF02798(GST_N)PF14497(GST_C_3) | 7 | TYR A 7PHE A 8VAL A 10GLY A 12ARG A 13TYR A 106GLY A 203 | GTS A 208 (-4.5A)GTS A 208 (-4.7A)NoneNoneGTS A 208 (-4.0A)NoneNone | 0.25A | 3n9jB-2gsrA:35.3 | 3n9jB-2gsrA:82.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gsr | CLASS PI GSTGLUTATHIONES-TRANSFERASE (Sus scrofa) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 106GLY A 203TYR A 7GLY A 12 | NoneNoneGTS A 208 (-4.5A)None | 0.65A | 3n9jB-2gsrA:35.3 | 3n9jB-2gsrA:82.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnl | GLUTATHIONES-TRANSFERASE 1 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | TYR A 32PHE A 33GLY A 37ARG A 38ILE A 127 | NoneNoneNoneGSH A 501 (-4.3A)None | 0.59A | 3n9jB-2hnlA:25.3 | 3n9jB-2hnlA:28.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j7c | BETA-GLUCOSIDASE A (Thermotogamaritima) |
PF00232(Glyco_hydro_1) | 4 | PHE A 151VAL A 212GLY A 215GLY A 155 | None | 0.64A | 3n9jB-2j7cA:undetectable | 3n9jB-2j7cA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kzx | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
PF04205(FMN_bind) | 4 | TYR A 6VAL A 26GLY A 4GLY A 29 | None | 0.80A | 3n9jB-2kzxA:undetectable | 3n9jB-2kzxA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r98 | PUTATIVEACETYLGLUTAMATESYNTHASE (Neisseriagonorrhoeae) |
PF00583(Acetyltransf_1)PF00696(AA_kinase) | 4 | VAL A 359GLY A 339ILE A 289GLY A 369 | ACO A 1 (-4.2A)NoneNoneACO A 1 (-3.2A) | 0.75A | 3n9jB-2r98A:undetectable | 3n9jB-2r98A:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wan | PULLULANASE (Bacillusacidopullulyticus) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | TYR A 210VAL A 233GLY A 208GLY A 237 | None | 0.77A | 3n9jB-2wanA:undetectable | 3n9jB-2wanA:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkn | FORMAMIDASE (Delftiaacidovorans) |
PF03069(FmdA_AmdA) | 4 | GLY A 256ILE A 260TYR A 328GLY A 360 | None | 0.75A | 3n9jB-2wknA:undetectable | 3n9jB-2wknA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zp2 | KINASE A INHIBITOR (Bacillussubtilis) |
PF02682(CT_C_D) | 4 | TYR A 142PHE A 152GLY A 154GLY A 185 | None | 0.77A | 3n9jB-2zp2A:undetectable | 3n9jB-2zp2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zqq | METHYLGLUTACONYL-COAHYDRATASE (Homo sapiens) |
PF00378(ECH_1) | 4 | GLY A 220ARG A 223ILE A 165GLY A 185 | None | 0.73A | 3n9jB-2zqqA:undetectable | 3n9jB-2zqqA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn4 | CARBONDIOXIDE-CONCENTRATING MECHANISM PROTEINCCMK HOMOLOG 1 (Synechocystissp.) |
PF00936(BMC) | 4 | VAL A 53GLY A 6ILE A 91GLY A 48 | None | 0.81A | 3n9jB-3bn4A:undetectable | 3n9jB-3bn4A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cru | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 7GLY A 12TYR A 111GLY A 205 | None | 0.64A | 3n9jB-3cruA:25.8 | 3n9jB-3cruA:29.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cru | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 111GLY A 205TYR A 7GLY A 12 | None | 0.77A | 3n9jB-3cruA:25.8 | 3n9jB-3cruA:29.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d0k | PUTATIVEPOLY(3-HYDROXYBUTYRATE) DEPOLYMERASELPQC (Bordetellaparapertussis) |
no annotation | 4 | TYR A 98PHE A 150GLY A 59GLY A 143 | NoneNoneSO4 A 306 (-3.2A)None | 0.73A | 3n9jB-3d0kA:undetectable | 3n9jB-3d0kA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6b | GLUTARYL-COADEHYDROGENASE (Burkholderiapseudomallei) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | TYR A 373VAL A 369ILE A 210GLY A 215 | None | 0.77A | 3n9jB-3d6bA:2.4 | 3n9jB-3d6bA:21.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gtu | GLUTATHIONES-TRANSFERASE (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 4 | TYR B 10GLY B 15ILE B 115TYR B 119 | None | 0.38A | 3n9jB-3gtuB:27.0 | 3n9jB-3gtuB:32.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8f | CYTOSOLAMINOPEPTIDASE (Pseudomonasputida) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | VAL A 484GLY A 299ARG A 302GLY A 481 | None | 0.72A | 3n9jB-3h8fA:undetectable | 3n9jB-3h8fA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibs | CONSERVEDHYPOTHETICAL PROTEINBATB (Bacteroidesthetaiotaomicron) |
PF00092(VWA) | 4 | TYR A 186GLY A 140ARG A 188GLY A 115 | None | 0.54A | 3n9jB-3ibsA:undetectable | 3n9jB-3ibsA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igx | TRANSALDOLASE (Francisellatularensis) |
PF00923(TAL_FSA) | 4 | TYR A 217PHE A 222ILE A 143GLY A 174 | None | 0.67A | 3n9jB-3igxA:undetectable | 3n9jB-3igxA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m16 | TRANSALDOLASE (Oleispiraantarctica) |
PF00923(TAL_FSA) | 4 | TYR A 220PHE A 225ILE A 147GLY A 178 | None | 0.82A | 3n9jB-3m16A:undetectable | 3n9jB-3m16A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m4r | UNCHARACTERIZEDPROTEIN (Thermoplasmaacidophilum) |
PF00596(Aldolase_II) | 4 | VAL A 31GLY A 25ILE A 67GLY A 35 | None | 0.82A | 3n9jB-3m4rA:undetectable | 3n9jB-3m4rA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 115PHE A 70ILE A 199GLY A 175 | None | 0.82A | 3n9jB-3mjoA:undetectable | 3n9jB-3mjoA:18.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3o76 | GLUTATHIONES-TRANSFERASE P 1 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 7 | TYR A 7PHE A 8VAL A 10GLY A 12ARG A 13TYR A 108GLY A 205 | NoneGTB A 210 (-4.5A)NoneNoneGTB A 210 (-3.9A)GTB A 210 (-4.1A)GTB A 210 (-3.7A) | 0.35A | 3n9jB-3o76A:36.1 | 3n9jB-3o76A:84.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3o76 | GLUTATHIONES-TRANSFERASE P 1 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 108GLY A 205TYR A 7GLY A 12 | GTB A 210 (-4.1A)GTB A 210 (-3.7A)NoneNone | 0.73A | 3n9jB-3o76A:36.1 | 3n9jB-3o76A:84.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogz | UDP-SUGARPYROPHOSPHORYLASE (Leishmaniamajor) |
PF01704(UDPGP) | 4 | VAL A 380GLY A 378ILE A 231GLY A 225 | None | 0.69A | 3n9jB-3ogzA:undetectable | 3n9jB-3ogzA:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ssq | CARBON DIOXIDECONCENTRATINGMECHANISM PROTEIN (Thermosynechococcuselongatus) |
PF00936(BMC) | 4 | VAL A 53GLY A 6ILE A 91GLY A 48 | None | 0.81A | 3n9jB-3ssqA:undetectable | 3n9jB-3ssqA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sss | CARBON DIOXIDECONCENTRATINGMECHANISM PROTEIN (Thermosynechococcuselongatus) |
PF00936(BMC) | 4 | VAL A 53GLY A 6ILE A 91GLY A 48 | None | 0.77A | 3n9jB-3sssA:undetectable | 3n9jB-3sssA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7v | BETA-GALACTOSIDASE (Caulobactervibrioides) |
PF02449(Glyco_hydro_42) | 5 | TYR A 445VAL A 489GLY A 470ARG A 356GLY A 486 | None | 1.43A | 3n9jB-3u7vA:undetectable | 3n9jB-3u7vA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrc | GALLATE DIOXYGENASE (Sphingomonaspaucimobilis) |
PF02900(LigB)PF07746(LigA) | 4 | TYR A 54GLY A 125ILE A 16GLY A 188 | None | 0.81A | 3n9jB-3wrcA:undetectable | 3n9jB-3wrcA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zx6 | HAMP,METHYL-ACCEPTINGCHEMOTAXIS PROTEIN I (Archaeoglobusfulgidus;Escherichiacoli) |
PF00015(MCPsignal)PF00672(HAMP) | 4 | VAL A 131GLY A 127ILE A 232GLY A 226 | None | 0.80A | 3n9jB-3zx6A:undetectable | 3n9jB-3zx6A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 4 | PHE A 539ILE A 254TYR A 506GLY A 537 | None | 0.80A | 3n9jB-4aioA:undetectable | 3n9jB-4aioA:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bg2 | PATF (Prochlorondidemni) |
no annotation | 4 | PHE A 27VAL A 29TYR A 67GLY A 65 | None | 0.80A | 3n9jB-4bg2A:undetectable | 3n9jB-4bg2A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4r | PHOSPHATEACETYLTRANSFERASE (Staphylococcusaureus) |
PF01515(PTA_PTB) | 4 | VAL A 20GLY A 120ILE A 140GLY A 109 | None | 0.76A | 3n9jB-4e4rA:undetectable | 3n9jB-4e4rA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4e | ATP-DEPENDENTPROTEASE SUBUNITHSLV (Escherichiacoli) |
PF00227(Proteasome) | 4 | VAL A 34GLY A 45ILE A 122GLY A 16 | None | 0.76A | 3n9jB-4g4eA:undetectable | 3n9jB-4g4eA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxp | BETA-GLUCOSIDASECHIMERIC PROTEIN (Thermotogamaritima;Trichodermareesei) |
PF00232(Glyco_hydro_1) | 4 | PHE A 158VAL A 219GLY A 222GLY A 162 | None | 0.75A | 3n9jB-4gxpA:undetectable | 3n9jB-4gxpA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nte | DEPH (Chromobacteriumviolaceum) |
PF07992(Pyr_redox_2) | 4 | GLY A 52ARG A 56ILE A 61GLY A 49 | NoneNoneNone NA A 303 (-4.5A) | 0.78A | 3n9jB-4nteA:undetectable | 3n9jB-4nteA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzk | UNCHARACTERIZEDPROTEIN ([Eubacterium]siraeum) |
PF14286(DHHW) | 4 | TYR A 108GLY A 111ILE A 164GLY A 371 | None | 0.73A | 3n9jB-4nzkA:undetectable | 3n9jB-4nzkA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqj | PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | TYR A 227PHE A 235GLY A 239GLY A 250 | None | 0.73A | 3n9jB-4oqjA:undetectable | 3n9jB-4oqjA:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ox7 | CARBONDIOXIDE-CONCENTRATING MECHANISM PROTEINCCMK (Synechococcuselongatus) |
PF00936(BMC) | 4 | VAL A 53GLY A 6ILE A 91GLY A 48 | None | 0.80A | 3n9jB-4ox7A:undetectable | 3n9jB-4ox7A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q5n | GLUTHATIONES-TRANSFERASE BLO T8 ISOFORM (Blomiatropicalis) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 8VAL A 11GLY A 13ILE A 116 | NoneNoneNoneGSH A 402 ( 4.5A) | 0.67A | 3n9jB-4q5nA:25.6 | 3n9jB-4q5nA:27.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASE (Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF00623(RNA_pol_Rpb1_2)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | PHE A 462VAL B 891GLY B 879GLY A 464 | None | 0.72A | 3n9jB-4qiwA:undetectable | 3n9jB-4qiwA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ql0 | FILAMENTOUSHEMAGGLUTININTRANSPORTER PROTEINFHAC (Bordetellapertussis) |
PF03865(ShlB)PF08479(POTRA_2)PF17287(POTRA_3) | 4 | TYR A 452VAL A 449GLY A 510GLY A 494 | None | 0.78A | 3n9jB-4ql0A:undetectable | 3n9jB-4ql0A:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r16 | 418AA LONGHYPOTHETICALUDP-N-ACETYL-D-MANNOSAMINURONIC ACIDDEHYDROGENASE (Pyrococcushorikoshii) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | VAL A 5GLY A 28ILE A 39GLY A 12 | None | 0.75A | 3n9jB-4r16A:undetectable | 3n9jB-4r16A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1d | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | TYR A 144VAL A 139GLY A 59GLY A 208 | None | 0.81A | 3n9jB-4r1dA:undetectable | 3n9jB-4r1dA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r20 | CYTOCHROME P450FAMILY 17POLYPEPTIDE 2 (Danio rerio) |
PF00067(p450) | 4 | VAL A 304GLY A 301ARG A 246ILE A 212 | NoneAER A 602 ( 3.8A)NoneAER A 602 (-3.2A) | 0.70A | 3n9jB-4r20A:undetectable | 3n9jB-4r20A:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvc | DEXTRANSUCRASE (Leuconostocmesenteroides) |
PF02324(Glyco_hydro_70) | 4 | TYR A1909VAL A1935GLY A1907GLY A1933 | None | 0.81A | 3n9jB-4tvcA:undetectable | 3n9jB-4tvcA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uz1 | NOTUM (Homo sapiens) |
PF03283(PAE) | 4 | VAL A 238GLY A 230ILE A 161GLY A 261 | None | 0.80A | 3n9jB-4uz1A:undetectable | 3n9jB-4uz1A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzj | NOTUM (Drosophilamelanogaster) |
PF03283(PAE) | 4 | VAL A 243GLY A 235ILE A 160GLY A 266 | None | 0.73A | 3n9jB-4uzjA:undetectable | 3n9jB-4uzjA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w66 | GLUTATHIONES-TRANSFERASE DOMAINPROTEIN (Haliangiumochraceum) |
PF14497(GST_C_3) | 4 | TYR A 9PHE A 10VAL A 12GLY A 14 | None | 0.19A | 3n9jB-4w66A:21.4 | 3n9jB-4w66A:27.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbh | PROTEIN NOTUMHOMOLOG (Homo sapiens) |
PF03283(PAE) | 4 | VAL A 238GLY A 230ILE A 161GLY A 261 | None | 0.77A | 3n9jB-4wbhA:undetectable | 3n9jB-4wbhA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr4 | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 6GLY A 11TYR A 110GLY A 204 | None | 0.78A | 3n9jB-4wr4A:25.8 | 3n9jB-4wr4A:27.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | PHE A 155VAL A 216GLY A 219GLY A 159 | None | 0.74A | 3n9jB-4zfmA:undetectable | 3n9jB-4zfmA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyj | DNMZ (Streptomycespeucetius) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | VAL A 71GLY A 111ARG A 110GLY A 68 | None | 0.78A | 3n9jB-4zyjA:undetectable | 3n9jB-4zyjA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfa | BONESIALOPROTEIN-BINDINGPROTEIN (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 4 | VAL A 198GLY A 292ILE A 177GLY A 308 | None | 0.49A | 3n9jB-5cfaA:undetectable | 3n9jB-5cfaA:18.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5d73 | GLUTATHIONES-TRANSFERASE (Wuchereriabancrofti) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | TYR A 7PHE A 8GLY A 12TYR A 106GLY A 204 | NoneGSH A 301 (-4.9A)NoneNoneNone | 0.52A | 3n9jB-5d73A:30.7 | 3n9jB-5d73A:42.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5d73 | GLUTATHIONES-TRANSFERASE (Wuchereriabancrofti) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TYR A 106GLY A 204TYR A 7GLY A 12 | None | 0.72A | 3n9jB-5d73A:30.7 | 3n9jB-5d73A:42.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewo | STRUCTURAL PROTEIN (Mamastrovirus 1) |
PF12226(Astro_capsid_p) | 5 | TYR A 588PHE A 582VAL A 543GLY A 586GLY A 546 | None | 1.10A | 3n9jB-5ewoA:undetectable | 3n9jB-5ewoA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gai | TAIL FIBER PROTEIN (Salmonellavirus P22) |
no annotation | 4 | VAL Y 26GLY Y 71ILE Y 73GLY Y 29 | None | 0.79A | 3n9jB-5gaiY:undetectable | 3n9jB-5gaiY:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idi | 1,4-BETA-D-GLUCANGLUCOHYDROLASE (Thermotoganeapolitana) |
PF00232(Glyco_hydro_1) | 4 | PHE A 149VAL A 210GLY A 213GLY A 153 | None | 0.68A | 3n9jB-5idiA:undetectable | 3n9jB-5idiA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihw | SERINE-ASPARTATEREPEAT-CONTAININGPROTEIN E (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 4 | VAL A 473GLY A 567ILE A 452GLY A 583 | None | 0.64A | 3n9jB-5ihwA:undetectable | 3n9jB-5ihwA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1l | TOXR-ACTIVATED GENE(TAGE) (Helicobacterpylori) |
PF01551(Peptidase_M23) | 4 | PHE A 208VAL A 189GLY A 228GLY B 208 | None | 0.70A | 3n9jB-5j1lA:undetectable | 3n9jB-5j1lA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwf | ASP/GLU-SPECIFICDIPEPTIDYL-PEPTIDASE (Porphyromonasgingivalis) |
PF10459(Peptidase_S46) | 4 | PHE A 256VAL A 73GLY A 78ARG A 77 | None | 0.81A | 3n9jB-5jwfA:undetectable | 3n9jB-5jwfA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0y | EUKARYOTICINITIATION FACTOR 2GAMMA SUBUNIT(EIF2-GAMMA) (Oryctolaguscuniculus) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 4 | VAL S 146GLY S 58ILE S 190GLY S 161 | None | 0.79A | 3n9jB-5k0yS:undetectable | 3n9jB-5k0yS:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ACYL-COADEHYDROGENASE (Clostridioidesdifficile) |
no annotation | 4 | TYR C 68VAL C 72GLY C 244GLY C 83 | None | 0.77A | 3n9jB-5ol2C:undetectable | 3n9jB-5ol2C:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT BTUNGSTEN-CONTAININGFORMYLMETHANOFURANDEHYDROGENASE 2SUBUNIT C (Methanothermobactersp. CaT2;Methanothermobacterwolfeii) |
PF00384(Molybdopterin)PF01493(GXGXG) | 4 | TYR B 207GLY C 202ILE C 251GLY C 221 | None | 0.79A | 3n9jB-5t5iB:undetectable | 3n9jB-5t5iB:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxn | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Pseudomonasaeruginosa) |
no annotation | 4 | PHE A 53VAL A 56GLY A 389ILE A 391 | None | 0.80A | 3n9jB-5uxnA:undetectable | 3n9jB-5uxnA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vn4 | ADENINEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE (Trypanosomabrucei) |
PF00156(Pribosyltran) | 4 | TYR A 10PHE A 200GLY A 177GLY A 174 | None | 0.81A | 3n9jB-5vn4A:undetectable | 3n9jB-5vn4A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv0 | SPIKE GLYCOPROTEIN (Aviancoronavirus) |
no annotation | 4 | GLY A 560ILE A 562TYR A 525GLY A 507 | None | 0.81A | 3n9jB-6cv0A:undetectable | 3n9jB-6cv0A:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC2 (Saccharomycescerevisiae) |
no annotation | 4 | PHE A 512VAL B 921GLY B 909GLY A 514 | None | 0.65A | 3n9jB-6f42A:undetectable | 3n9jB-6f42A:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsw | MU CLASS GLUTATHIONES-TRANSFERASE OFISOENZYME 3-3 (Rattus rattus) |
PF00043(GST_C)PF02798(GST_N) | 4 | TYR A 6VAL A 9GLY A 11ILE A 111 | NoneNoneGPS A 221 (-3.5A)GPS A 221 (-4.5A) | 0.61A | 3n9jB-6gswA:25.6 | 3n9jB-6gswA:30.00 |