SIMILAR PATTERNS OF AMINO ACIDS FOR 3N9J_A_EAAA210

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bud PROTEIN (ACUTOLYSIN
A)


(Deinagkistrodon
acutus)
PF01421
(Reprolysin)
4 VAL A 150
ARG A 187
ILE A  49
TYR A  44
None
0.84A 3n9jA-1budA:
undetectable
3n9jA-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c1d L-PHENYLALANINE
DEHYDROGENASE


(Rhodococcus sp.)
PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N)
4 PHE A 137
ILE A 106
TYR A 113
GLY A  39
None
None
None
PHE  A 361 (-3.7A)
0.96A 3n9jA-1c1dA:
undetectable
3n9jA-1c1dA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3


(Rattus
norvegicus)
PF06325
(PrmA)
4 TYR A 330
PHE A 334
ILE A 226
TYR A 221
None
None
None
SAH  A 529 (-3.5A)
0.87A 3n9jA-1f3lA:
undetectable
3n9jA-1f3lA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7u ARGINYL-TRNA
SYNTHETASE


(Saccharomyces
cerevisiae)
PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1)
4 TYR A 471
VAL A 405
ILE A 167
GLY A 161
None
0.95A 3n9jA-1f7uA:
2.5
3n9jA-1f7uA:
16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gsq GLUTATHIONE
S-TRANSFERASE


(Todarodes
pacificus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   7
PHE A   8
ARG A  13
TRP A  38
None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
0.64A 3n9jA-1gsqA:
25.7
3n9jA-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1huj INORGANIC
PYROPHOSPHATASE


(Saccharomyces
cerevisiae)
PF00719
(Pyrophosphatase)
4 TYR A  15
VAL A  17
ILE A  49
GLY A 132
None
0.94A 3n9jA-1hujA:
undetectable
3n9jA-1hujA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsc ACETOHYDROXY-ACID
SYNTHASE


(Saccharomyces
cerevisiae)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 PHE A 111
VAL A 159
ILE A 182
GLY A 143
None
0.87A 3n9jA-1jscA:
undetectable
3n9jA-1jscA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka9 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE


(Thermus
thermophilus)
PF00117
(GATase)
4 TYR H  10
PHE H  59
VAL H  55
ILE H  81
None
0.94A 3n9jA-1ka9H:
undetectable
3n9jA-1ka9H:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
None
0.73A 3n9jA-1kgpA:
undetectable
3n9jA-1kgpA:
20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
7 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
ILE A 104
TYR A 108
None
GSH  A 504 (-4.7A)
None
GSH  A 504 (-3.7A)
GSH  A 504 (-3.9A)
None
None
0.70A 3n9jA-1lbkA:
36.1
3n9jA-1lbkA:
97.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0u GST2 GENE PRODUCT

(Drosophila
melanogaster)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A  54
PHE A  55
VAL A  57
TRP A  85
GSH  A 500 (-4.7A)
GSH  A 500 (-4.8A)
None
GSH  A 500 (-3.6A)
0.40A 3n9jA-1m0uA:
23.1
3n9jA-1m0uA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd2 HEMATOPOIETIC
PROSTAGLANDIN D
SYNTHASE


(Rattus
norvegicus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR 1   8
PHE 1   9
ARG 1  14
TRP 1  39
GSH  1 301 (-4.8A)
None
GSH  1 301 (-3.4A)
GSH  1 301 (-3.6A)
0.65A 3n9jA-1pd21:
23.9
3n9jA-1pd21:
28.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE


(Geobacillus
stearothermophilus)
PF06964
(Alpha-L-AF_C)
4 VAL A 413
ILE A  23
TYR A  24
GLY A 383
None
0.80A 3n9jA-1pz3A:
undetectable
3n9jA-1pz3A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qc5 PROTEIN (ALPHA1
BETA1 INTEGRIN)


(Homo sapiens)
PF00092
(VWA)
4 VAL B 338
ARG B 466
ILE B 456
GLY B 415
None
0.91A 3n9jA-1qc5B:
undetectable
3n9jA-1qc5B:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
4 TYR A 105
PHE A  60
ILE A 189
GLY A 165
None
0.81A 3n9jA-1r2fA:
undetectable
3n9jA-1r2fA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfj 3-DEHYDROQUINATE
DEHYDRATASE


(Staphylococcus
aureus)
PF01487
(DHquinase_I)
4 VAL A   4
ARG A 202
ILE A 192
GLY A 210
None
DHK  A 239 (-2.6A)
DHK  A 239 ( 4.2A)
None
0.93A 3n9jA-1sfjA:
undetectable
3n9jA-1sfjA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2


(Onchocerca
volvulus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
None
GSH  A1001 (-4.8A)
None
None
0.49A 3n9jA-1tu7A:
30.7
3n9jA-1tu7A:
42.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA


(Schistosoma
mansoni)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A  10
PHE A  11
ARG A  16
TRP A  41
None
None
GSH  A 301 (-4.2A)
GSH  A 301 (-4.0A)
0.92A 3n9jA-1u3iA:
23.5
3n9jA-1u3iA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT


(Mycobacterium
tuberculosis)
PF00268
(Ribonuc_red_sm)
4 TYR A 110
PHE A  65
ILE A 194
GLY A 170
None
0.81A 3n9jA-1uzrA:
undetectable
3n9jA-1uzrA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   8
PHE A   9
ARG A  14
TRP A  39
None
O16  A3201 (-3.0A)
O16  A3201 ( 3.8A)
GSH  A3200 (-4.1A)
0.70A 3n9jA-1v40A:
24.4
3n9jA-1v40A:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE


(Pyrobaculum
aerophilum)
PF09171
(AGOG)
4 PHE A  76
VAL A  38
ILE A 148
GLY A  47
None
0.91A 3n9jA-1xqpA:
undetectable
3n9jA-1xqpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8q U8 SNORNA-BINDING
PROTEIN X29


(Xenopus laevis)
PF00293
(NUDIX)
5 PHE A 172
ARG A 156
ILE A  54
TYR A 160
GLY A 168
None
1.29A 3n9jA-2a8qA:
undetectable
3n9jA-2a8qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2x INTEGRIN ALPHA-1

(Rattus
norvegicus)
PF00092
(VWA)
4 VAL A 152
ARG A 280
ILE A 270
GLY A 229
None
0.85A 3n9jA-2b2xA:
undetectable
3n9jA-2b2xA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcu PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 3


(Arabidopsis
thaliana)
PF00753
(Lactamase_B)
4 TYR A  29
PHE A 150
ILE A 157
GLY A 152
None
None
EDO  A2003 (-4.9A)
None
0.95A 3n9jA-2gcuA:
undetectable
3n9jA-2gcuA:
23.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE


(Sus scrofa)
PF02798
(GST_N)
PF14497
(GST_C_3)
7 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
TYR A 106
GLY A 203
GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
GTS  A 208 (-4.0A)
GTS  A 208 (-3.9A)
None
None
0.27A 3n9jA-2gsrA:
35.6
3n9jA-2gsrA:
82.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gup ROK FAMILY PROTEIN

(Streptococcus
pneumoniae)
PF00480
(ROK)
4 TYR A  78
VAL A  76
ILE A  30
GLY A   9
None
0.81A 3n9jA-2gupA:
undetectable
3n9jA-2gupA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnl GLUTATHIONE
S-TRANSFERASE 1


(Onchocerca
volvulus)
PF02798
(GST_N)
PF14497
(GST_C_3)
5 TYR A  32
PHE A  33
ARG A  38
TRP A  63
ILE A 127
None
None
GSH  A 501 (-4.3A)
GSH  A 501 (-3.9A)
None
0.69A 3n9jA-2hnlA:
25.4
3n9jA-2hnlA:
28.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE


(Streptomyces
clavuligerus)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 TYR A 561
PHE A 412
ILE A 460
GLY A 411
TPP  A 600 ( 4.2A)
None
None
TPP  A 600 (-3.6A)
0.91A 3n9jA-2ihtA:
undetectable
3n9jA-2ihtA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2il5 HYPOTHETICAL PROTEIN

(Staphylococcus
aureus)
PF08327
(AHSA1)
4 TYR A  78
VAL A  54
TRP A  30
ILE A  50
None
0.92A 3n9jA-2il5A:
undetectable
3n9jA-2il5A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2isj BLUB

(Sinorhizobium
meliloti)
PF00881
(Nitroreductase)
4 ARG A  72
TRP A 189
ILE A  47
GLY A 193
None
0.75A 3n9jA-2isjA:
undetectable
3n9jA-2isjA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE


(Vibrio cholerae)
PF03167
(UDG)
5 TYR A  66
VAL A  79
ILE A  92
TYR A  93
GLY A 109
None
1.09A 3n9jA-2jhqA:
undetectable
3n9jA-2jhqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2msk NITROGEN REGULATION
PROTEIN NR(I)


(Salmonella
enterica)
PF00072
(Response_reg)
4 PHE A  33
VAL A   9
ILE A  69
GLY A  36
None
0.94A 3n9jA-2mskA:
undetectable
3n9jA-2mskA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p14 HETERODIMERIC
RESTRICTION
ENDONUCLEASE
R.BSPD6I SMALL
SUBUNIT


(Bacillus sp. D6)
PF09491
(RE_AlwI)
4 TYR A   8
VAL A 135
ILE A  72
GLY A 110
None
0.86A 3n9jA-2p14A:
undetectable
3n9jA-2p14A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE


(Aquifex
aeolicus)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 TYR A  51
ILE A 212
TYR A 215
GLY A 243
None
0.88A 3n9jA-2p3eA:
undetectable
3n9jA-2p3eA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcs CONSERVED PROTEIN

(Geobacillus
kaustophilus)
PF06240
(COXG)
4 VAL A 117
ILE A  50
TYR A  59
GLY A  85
UNL  A 161 ( 4.9A)
UNL  A 161 ( 4.8A)
UNL  A 161 ( 3.9A)
None
0.97A 3n9jA-2pcsA:
undetectable
3n9jA-2pcsA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc8 N-ACYLAMINO ACID
RACEMASE


(Thermus
thermophilus)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 VAL A 102
ARG A  64
ILE A  10
GLY A  47
None
0.90A 3n9jA-2zc8A:
undetectable
3n9jA-2zc8A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmg PUTATIVE
BETA-GALACTOSIDASE


(Bacteroides
fragilis)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982)
4 PHE A 132
ARG A 126
ILE A 160
GLY A 130
None
0.91A 3n9jA-3cmgA:
undetectable
3n9jA-3cmgA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE


(Leishmania
naiffi)
PF03167
(UDG)
4 TYR A 208
VAL A 221
ILE A 234
GLY A 251
URB  A 401 ( 3.3A)
None
None
None
0.96A 3n9jA-3cxmA:
undetectable
3n9jA-3cxmA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE


(Burkholderia
pseudomallei)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 TYR A 373
VAL A 369
ILE A 210
GLY A 215
None
0.71A 3n9jA-3d6bA:
2.1
3n9jA-3d6bA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN


(Geobacillus
kaustophilus)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6)
4 TYR A1298
VAL A1348
ILE A1132
GLY A1154
None
0.95A 3n9jA-3f2bA:
undetectable
3n9jA-3f2bA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3frm UNCHARACTERIZED
CONSERVED PROTEIN


(Staphylococcus
epidermidis)
PF13673
(Acetyltransf_10)
4 TYR A 237
VAL A 218
ILE A 205
GLY A 210
None
0.96A 3n9jA-3frmA:
undetectable
3n9jA-3frmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftb HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE


(Clostridium
acetobutylicum)
PF00155
(Aminotran_1_2)
4 PHE A 186
ILE A  91
TYR A 111
GLY A 151
None
0.89A 3n9jA-3ftbA:
undetectable
3n9jA-3ftbA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC5


(Schizosaccharomyces
pombe)
PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
PF01194
(RNA_pol_N)
4 VAL C 236
TRP C 171
ILE J   5
GLY J  11
None
0.76A 3n9jA-3h0gC:
undetectable
3n9jA-3h0gC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6


(Escherichia
virus T4)
no annotation 4 PHE A 517
VAL A 538
ILE A 592
GLY A 556
None
0.92A 3n9jA-3h2tA:
undetectable
3n9jA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i83 2-DEHYDROPANTOATE
2-REDUCTASE


(Methylococcus
capsulatus)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 PHE A 127
ILE A  11
TYR A  15
GLY A 144
None
0.94A 3n9jA-3i83A:
undetectable
3n9jA-3i83A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igx TRANSALDOLASE

(Francisella
tularensis)
PF00923
(TAL_FSA)
4 TYR A 217
PHE A 222
ILE A 143
GLY A 174
None
0.67A 3n9jA-3igxA:
undetectable
3n9jA-3igxA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is6 PUTATIVE PERMEASE
PROTEIN, ABC
TRANSPORTER


(Porphyromonas
gingivalis)
PF12704
(MacB_PCD)
4 TYR A 262
VAL A  84
ILE A 216
GLY A  82
None
0.97A 3n9jA-3is6A:
undetectable
3n9jA-3is6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG


(Bacillus
subtilis)
PF00266
(Aminotran_5)
4 PHE A  99
VAL A 145
ILE A 106
GLY A 100
PLP  A 419 (-3.5A)
None
None
None
0.87A 3n9jA-3islA:
undetectable
3n9jA-3islA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kc2 UNCHARACTERIZED
PROTEIN YKR070W


(Saccharomyces
cerevisiae)
PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6)
4 TYR A 111
VAL A 107
ILE A  79
GLY A  56
None
0.82A 3n9jA-3kc2A:
undetectable
3n9jA-3kc2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmk METABOTROPIC
GLUTAMATE RECEPTOR 5


(Homo sapiens)
PF01094
(ANF_receptor)
4 PHE A 337
VAL A 334
ILE A 404
GLY A 398
None
0.95A 3n9jA-3lmkA:
undetectable
3n9jA-3lmkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica)
PF00923
(TAL_FSA)
4 TYR A 220
PHE A 225
ILE A 147
GLY A 178
None
0.81A 3n9jA-3m16A:
undetectable
3n9jA-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
None
0.81A 3n9jA-3mjoA:
undetectable
3n9jA-3mjoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0q PUTATIVE
AROMATIC-RING
HYDROXYLATING
DIOXYGENASE


(Ruegeria sp.
TM1040)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 VAL A 360
TRP A 193
ILE A 183
GLY A 187
None
0.90A 3n9jA-3n0qA:
undetectable
3n9jA-3n0qA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 4 TYR B 105
PHE B  60
ILE B 189
GLY B 165
None
0.92A 3n9jA-3n3bB:
undetectable
3n9jA-3n3bB:
19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1


(Mus musculus)
PF02798
(GST_N)
PF14497
(GST_C_3)
7 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.0A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.46A 3n9jA-3o76A:
36.5
3n9jA-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE


(Aliivibrio
fischeri)
PF02719
(Polysacc_synt_2)
4 TYR A 157
VAL A 113
ILE A  95
TYR A 100
None
None
NAD  A 501 (-3.9A)
None
0.93A 3n9jA-3pvzA:
undetectable
3n9jA-3pvzA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ruc WBGU

(Plesiomonas
shigelloides)
PF01370
(Epimerase)
4 VAL A  24
TRP A  19
ILE A 125
GLY A  45
None
0.90A 3n9jA-3rucA:
undetectable
3n9jA-3rucA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sh5 LG3 PEPTIDE

(Homo sapiens)
PF00054
(Laminin_G_1)
4 PHE A 152
VAL A 144
ILE A 138
GLY A 155
None
0.70A 3n9jA-3sh5A:
undetectable
3n9jA-3sh5A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t90 GLUCOSE-6-PHOSPHATE
ACETYLTRANSFERASE 1


(Arabidopsis
thaliana)
PF00583
(Acetyltransf_1)
4 PHE A 107
VAL A 104
ILE A  64
GLY A  68
None
0.89A 3n9jA-3t90A:
undetectable
3n9jA-3t90A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbj ACTIBIND

(Aspergillus
niger)
PF00445
(Ribonuclease_T2)
4 TYR A 237
VAL A 228
ILE A 145
GLY A 230
None
0.83A 3n9jA-3tbjA:
undetectable
3n9jA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr7 URACIL-DNA
GLYCOSYLASE


(Coxiella
burnetii)
PF03167
(UDG)
4 TYR A  69
VAL A  82
ILE A  95
GLY A 111
None
0.92A 3n9jA-3tr7A:
undetectable
3n9jA-3tr7A:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3vpq GLUTATHIONE
S-TRANSFERASE SIGMA


(Bombyx mori)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   8
PHE A   9
VAL A  11
TRP A  39
GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
0.42A 3n9jA-3vpqA:
20.5
3n9jA-3vpqA:
31.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 VAL A 592
ILE A 267
TYR A 225
GLY A 569
None
0.90A 3n9jA-3wdjA:
undetectable
3n9jA-3wdjA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N)
4 PHE A 476
TRP A 432
TYR A 438
GLY A 429
None
ACR  A1001 ( 4.6A)
None
None
0.91A 3n9jA-3welA:
undetectable
3n9jA-3welA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aio LIMIT DEXTRINASE

(Hordeum vulgare)
PF02922
(CBM_48)
PF11852
(DUF3372)
4 PHE A 539
ILE A 254
TYR A 506
GLY A 537
None
0.81A 3n9jA-4aioA:
undetectable
3n9jA-4aioA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni)
no annotation 4 PHE A  27
VAL A  29
TYR A  67
GLY A  65
None
0.80A 3n9jA-4bg2A:
undetectable
3n9jA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni)
no annotation 4 VAL A  29
ARG A  21
TYR A  67
GLY A  65
None
0.95A 3n9jA-4bg2A:
undetectable
3n9jA-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwr PROTEIN
CORRESPONDING TO
LOCUS C5321 FROM
CFT073 E.COLI STRAIN


(Escherichia
coli)
PF08238
(Sel1)
4 PHE A 414
VAL A 380
ILE A 421
GLY A 415
EDO  A1490 (-4.7A)
None
EDO  A1477 (-3.3A)
None
0.93A 3n9jA-4bwrA:
undetectable
3n9jA-4bwrA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE


(Thermotoga
maritima)
PF13597
(NRDD)
4 TYR A 227
ILE A 555
TYR A 584
GLY A 361
None
0.94A 3n9jA-4conA:
undetectable
3n9jA-4conA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5v PUTATIVE THUA-LIKE
PROTEIN


(Parabacteroides
merdae)
PF06283
(ThuA)
4 PHE A 289
VAL A 285
TRP A 192
GLY A 187
None
None
None
EDO  A 407 ( 4.7A)
0.93A 3n9jA-4e5vA:
undetectable
3n9jA-4e5vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqj HEMAGGLUTININ

(Influenza B
virus)
PF00509
(Hemagglutinin)
4 TYR A 202
VAL A 160
ILE A 243
GLY A 138
None
0.97A 3n9jA-4fqjA:
undetectable
3n9jA-4fqjA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE


(Mycolicibacterium
thermoresistibile)
PF16113
(ECH_2)
4 TYR A  92
VAL A 148
ILE A  73
GLY A 116
None
0.80A 3n9jA-4hdtA:
undetectable
3n9jA-4hdtA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN


(Pseudomonas)
PF01804
(Penicil_amidase)
4 TYR B  32
PHE B  31
VAL B  49
ILE B 176
GLJ  B 601 (-4.9A)
None
None
None
0.93A 3n9jA-4hstB:
undetectable
3n9jA-4hstB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1b POLYSACCHARIDE
DEACETYLASE


(Bacillus
anthracis)
PF01522
(Polysacc_deac_1)
4 ARG A 132
ILE A 167
TYR A 123
GLY A 117
None
0.96A 3n9jA-4m1bA:
undetectable
3n9jA-4m1bA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n83 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Streptococcus
sanguinis)
PF00268
(Ribonuc_red_sm)
4 TYR A 104
PHE A  59
ILE A 188
GLY A 164
None
0.86A 3n9jA-4n83A:
undetectable
3n9jA-4n83A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4na3 POLYKETIDE SYNTHASE
PKSJ


(Bacillus
subtilis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 ARG A 266
ILE A 300
TYR A 295
GLY A 427
None
0.96A 3n9jA-4na3A:
undetectable
3n9jA-4na3A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE


(Geobacter
sulfurreducens)
PF00171
(Aldedh)
PF01619
(Pro_dh)
4 VAL A 938
ARG A 933
ILE A 943
GLY A 919
EDO  A1104 (-4.7A)
None
None
None
0.92A 3n9jA-4nmeA:
undetectable
3n9jA-4nmeA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE


(Rhodotorula
mucilaginosa)
PF13561
(adh_short_C2)
4 PHE A  76
VAL A  78
ILE A  33
GLY A  53
None
0.86A 3n9jA-4o0lA:
undetectable
3n9jA-4o0lA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pue ENDO-1,4-BETA-XYLANA
SE


(Geobacillus
stearothermophilus)
PF00331
(Glyco_hydro_10)
4 PHE A 360
ILE A 284
TYR A 281
GLY A 363
None
0.76A 3n9jA-4pueA:
undetectable
3n9jA-4pueA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7b CHOLINE KINASE

(Streptococcus
pneumoniae)
PF01633
(Choline_kinase)
4 TRP A 251
ILE A 144
TYR A 146
GLY A 269
CHT  A 301 ( 3.6A)
None
None
None
0.93A 3n9jA-4r7bA:
undetectable
3n9jA-4r7bA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3m 2-DEHYDROPANTOATE
2-REDUCTASE


(Staphylococcus
aureus)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 TYR A  40
VAL A 126
ILE A 117
GLY A  11
None
None
None
NAP  A 500 (-3.1A)
0.83A 3n9jA-4s3mA:
undetectable
3n9jA-4s3mA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA


(Bacillus
subtilis)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
4 VAL A  23
ILE A  31
TYR A 125
GLY A  48
None
0.93A 3n9jA-4tr6A:
undetectable
3n9jA-4tr6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqm URACIL-DNA
GLYCOSYLASE


(Deinococcus
radiodurans)
PF03167
(UDG)
5 TYR A  85
VAL A  98
ILE A 111
TYR A 112
GLY A 128
CL  A1245 (-4.3A)
None
None
None
None
1.17A 3n9jA-4uqmA:
undetectable
3n9jA-4uqmA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w66 GLUTATHIONE
S-TRANSFERASE DOMAIN
PROTEIN


(Haliangium
ochraceum)
PF14497
(GST_C_3)
4 TYR A   9
PHE A  10
VAL A  12
TRP A  40
None
0.29A 3n9jA-4w66A:
21.5
3n9jA-4w66A:
27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brq GLYCOSIDE HYDROLASE
FAMILY 13


(Bacillus
licheniformis)
PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C)
4 VAL A 421
ILE A  43
TYR A  15
GLY A 367
None
0.97A 3n9jA-5brqA:
undetectable
3n9jA-5brqA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1e PECTINESTERASE

(Aspergillus
niger)
PF01095
(Pectinesterase)
4 TYR A  73
VAL A 102
TYR A  67
GLY A  89
None
0.92A 3n9jA-5c1eA:
undetectable
3n9jA-5c1eA:
20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE


(Wuchereria
bancrofti)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
None
GSH  A 301 (-4.9A)
None
None
0.52A 3n9jA-5d73A:
30.9
3n9jA-5d73A:
42.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dis GTP-BINDING NUCLEAR
PROTEIN RAN


(Homo sapiens)
PF00071
(Ras)
4 TYR B 155
VAL B 124
TYR B 146
GLY B 121
None
0.93A 3n9jA-5disB:
undetectable
3n9jA-5disB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1)
PF12226
(Astro_capsid_p)
4 TYR A 588
PHE A 582
VAL A 543
GLY A 546
None
0.91A 3n9jA-5ewoA:
undetectable
3n9jA-5ewoA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5


(Saccharomyces
cerevisiae)
PF12717
(Cnd1)
4 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.91A 3n9jA-5frsA:
undetectable
3n9jA-5frsA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fub PROTEIN ARGININE
METHYLTRANSFERASE 2


(Danio rerio)
PF13649
(Methyltransf_25)
4 PHE A 304
VAL A 284
ILE A 385
GLY A 302
None
0.97A 3n9jA-5fubA:
undetectable
3n9jA-5fubA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2


(Saccharomyces
cerevisiae)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
4 TYR B 859
VAL B 968
ARG B 942
GLY B 947
None
0.90A 3n9jA-5ip9B:
undetectable
3n9jA-5ip9B:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK


(Gluconacetobacter
diazotrophicus)
PF00148
(Oxidored_nitro)
PF11844
(DUF3364)
4 TYR B 196
PHE B  76
ILE B 249
GLY B  80
None
0.79A 3n9jA-5kohB:
undetectable
3n9jA-5kohB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans)
PF03639
(Glyco_hydro_81)
4 TYR A 671
PHE A 674
VAL A 645
ILE A 581
None
0.96A 3n9jA-5v1wA:
2.4
3n9jA-5v1wA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans)
no annotation 4 TYR B  17
PHE B 130
ILE B 137
GLY B 132
None
0.96A 3n9jA-5ve3B:
undetectable
3n9jA-5ve3B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x55 PROBABLE URACIL-DNA
GLYCOSYLASE


(Acanthamoeba
polyphaga
mimivirus)
PF03167
(UDG)
4 TYR A 193
VAL A 211
ILE A 224
GLY A 241
None
0.85A 3n9jA-5x55A:
undetectable
3n9jA-5x55A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Colwellia
psychrerythraea)
PF00275
(EPSP_synthase)
4 PHE A 250
VAL A 261
ILE A   9
GLY A 254
None
0.90A 3n9jA-5xwbA:
undetectable
3n9jA-5xwbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0q UPF0348 PROTEIN
B4417_3650


(Bacillus
subtilis)
no annotation 4 TYR A  72
PHE A  41
VAL A  76
GLY A  45
None
0.83A 3n9jA-5y0qA:
undetectable
3n9jA-5y0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5k DRAXIN
NETRIN RECEPTOR DCC


(Rattus
norvegicus)
no annotation 4 ARG B 282
ILE A 387
TYR A 398
GLY A 396
None
0.95A 3n9jA-5z5kB:
undetectable
3n9jA-5z5kB:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ap4 DNA POLYMERASE III
SUBUNIT BETA


(Acinetobacter
baumannii)
no annotation 4 VAL A  21
ILE A  29
TYR A 119
GLY A  46
None
0.95A 3n9jA-6ap4A:
undetectable
3n9jA-6ap4A:
18.36