SIMILAR PATTERNS OF AMINO ACIDS FOR 3N62_B_MTLB870_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ehx SCAFFOLDIN PROTEIN

([Clostridium]
cellulolyticum) 		PF03442
(CBM_X2) 		4 ASN A  78
GLN A   2
PHE A  72
ASN A  33
 None
 1.11A 3n62B-1ehxA:
undetectable		 3n62B-1ehxA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		4 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.25A 3n62B-1iw8A:
0.0		 3n62B-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwl OUTER-MEMBRANE
LIPOPROTEINS CARRIER
PROTEIN

(Escherichia
coli) 		PF03548
(LolA) 		4 SER A  57
GLN A  53
ASN A  70
ASP A  55
 None
 1.23A 3n62B-1iwlA:
0.0		 3n62B-1iwlA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knr L-ASPARTATE OXIDASE

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.15A 3n62B-1knrA:
0.0		 3n62B-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lkt TAILSPIKE PROTEIN

(Salmonella
virus P22) 		PF09008
(Head_binding) 		4 SER A  20
ARG A  21
GLN A  99
ASP A 101
 None
 1.07A 3n62B-1lktA:
undetectable		 3n62B-1lktA:
14.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lzx NITRIC-OXIDE
SYNTHASE

(Rattus
norvegicus) 		PF02898
(NO_synthase) 		7 ARG A 481
ASN A 498
GLN A 500
PHE A 501
ASN A 569
ASP A 709
TRP A 711
 None
 0.30A 3n62B-1lzxA:
62.4		 3n62B-1lzxA:
99.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lzx NITRIC-OXIDE
SYNTHASE

(Rattus
norvegicus) 		PF02898
(NO_synthase) 		7 SER A 477
ARG A 481
ASN A 498
GLN A 500
PHE A 501
ASN A 569
TRP A 711
 None
 0.60A 3n62B-1lzxA:
62.4		 3n62B-1lzxA:
99.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		5 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.66A 3n62B-1m9qA:
59.2		 3n62B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.74A 3n62B-1m9qA:
59.2		 3n62B-1m9qA:
64.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1noz DNA POLYMERASE

(Escherichia
virus T4) 		PF03104
(DNA_pol_B_exo1) 		4 ASN A 368
PHE A 367
ASN A  84
ASP A 363
 None
 1.31A 3n62B-1nozA:
0.0		 3n62B-1nozA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olp ALPHA-TOXIN

(Clostridium
sardiniense) 		PF00882
(Zn_dep_PLPC)
PF01477
(PLAT) 		4 SER A  96
ARG A  99
ASN A  93
ASP A  92
 None
 1.09A 3n62B-1olpA:
0.0		 3n62B-1olpA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oul STRINGENT STARVATION
PROTEIN B HOMOLOG

(Haemophilus
influenzae) 		PF04386
(SspB) 		4 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.99A 3n62B-1oulA:
undetectable		 3n62B-1oulA:
16.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		5 SER A 256
ARG A 260
PHE A 280
ASN A 348
TRP A 490
 None
 0.78A 3n62B-1qw5A:
58.3		 3n62B-1qw5A:
63.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twb STRINGENT STARVATION
PROTEIN B HOMOLOG

(Haemophilus
influenzae) 		PF04386
(SspB) 		4 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 1.03A 3n62B-1twbA:
undetectable		 3n62B-1twbA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwy CARBOXYPEPTIDASE M

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg) 		4 SER A 197
ASN A 185
GLN A 249
PHE A 183
 None
 1.26A 3n62B-1uwyA:
undetectable		 3n62B-1uwyA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT

(Corynebacterium
sp. U-96) 		PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4) 		4 ARG A 253
ASN A 381
PHE A 403
ASP A 397
 None
 1.27A 3n62B-1vrqA:
undetectable		 3n62B-1vrqA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 SER A 381
ARG A 380
PHE A 321
ASP A 323
 None
 1.28A 3n62B-1xkhA:
undetectable		 3n62B-1xkhA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]

(Anaerobiospirillum
succiniciproducens) 		PF01293
(PEPCK_ATP) 		4 SER A 379
ASN A 514
GLN A 512
PHE A 511
 None
 1.25A 3n62B-1ytmA:
undetectable		 3n62B-1ytmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvl SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
PF02865
(STAT_int) 		4 GLN A  95
PHE A  94
ASN A  89
ASP A  92
 None
 1.30A 3n62B-1yvlA:
undetectable		 3n62B-1yvlA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9v GMP SYNTHASE

(Thermoplasma
acidophilum) 		PF00117
(GATase) 		4 ASN A 128
GLN A 165
ASN A  54
ASP A 131
 None
 1.31A 3n62B-2a9vA:
undetectable		 3n62B-2a9vA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqw PUTATIVE
OROTIDINE-MONOPHOSPH
ATE-DECARBOXYLASE

(Plasmodium
yoelii) 		PF00215
(OMPdecase) 		4 SER A 202
ASN A 207
PHE A 203
ASN A 199
 None
 1.15A 3n62B-2aqwA:
undetectable		 3n62B-2aqwA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ckr ENDOGLUCANASE E-5

(Thermobifida
fusca) 		PF00150
(Cellulase) 		4 SER A 392
GLN A 402
PHE A 401
ASN A 390
 None
 1.04A 3n62B-2ckrA:
undetectable		 3n62B-2ckrA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw6 BLL6730 PROTEIN

(Bradyrhizobium
japonicum) 		PF13378
(MR_MLE_C) 		4 ASN A 266
GLN A 290
ASN A  21
ASP A 213
 None
None
TAR  A1001 (-3.9A)
MG  A2001 ( 2.5A)
 1.31A 3n62B-2dw6A:
undetectable		 3n62B-2dw6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5v L-ASPARTATE OXIDASE

(Sulfurisphaera
tokodaii) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A 261
GLN A 210
PHE A 211
ASP A 258
 None
 1.28A 3n62B-2e5vA:
undetectable		 3n62B-2e5vA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iop CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 SER A  37
ARG A  33
ASN A  38
ASP A  41
 None
None
ADP  A1001 (-3.9A)
None
 0.93A 3n62B-2iopA:
undetectable		 3n62B-2iopA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jxy MACROPHAGE
METALLOELASTASE

(Homo sapiens) 		PF00045
(Hemopexin) 		4 SER A 464
PHE A 300
ASN A 465
TRP A 307
 None
 1.09A 3n62B-2jxyA:
undetectable		 3n62B-2jxyA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kcy 30S RIBOSOMAL
PROTEIN S8E

(Methanothermobacter
thermautotrophicus) 		PF01201
(Ribosomal_S8e) 		4 SER A  75
ARG A  76
ASN A  84
ASP A  80
 None
 1.06A 3n62B-2kcyA:
undetectable		 3n62B-2kcyA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lfs UNCHARACTERIZED
PROTEIN, OSMOLARITY
SENSOR PROTEIN ENVZ
CHIMERA

(Shigella
flexneri;
Archaeoglobus
fulgidus) 		PF00512
(HisKA)
PF00672
(HAMP) 		4 SER A 288
PHE A 291
ASN A 289
ASP A 292
 None
 1.31A 3n62B-2lfsA:
undetectable		 3n62B-2lfsA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpr MALTOPORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.30A 3n62B-2mprA:
undetectable		 3n62B-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis) 		PF01678
(DAP_epimerase) 		4 ARG A 214
GLN A 178
ASN A 212
ASP A 175
 None
 1.28A 3n62B-2otnA:
undetectable		 3n62B-2otnA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p24 H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A-U ALPHA
CHAIN
H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A-U BETA
CHAIN

(Mus musculus;
Mus musculus) 		PF00993
(MHC_II_alpha)
PF07654
(C1-set)
PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 SER A 144
ARG B 134
GLN A  88
ASP A 110
 None
 1.15A 3n62B-2p24A:
undetectable		 3n62B-2p24A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica) 		PF04962
(KduI) 		4 ARG A 190
ASN A 217
GLN A 195
PHE A 191
 SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
 0.93A 3n62B-2qjvA:
undetectable		 3n62B-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4g TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		PF12009
(Telomerase_RBD) 		4 ASN A 317
GLN A 282
PHE A 318
ASN A 322
 None
 1.28A 3n62B-2r4gA:
undetectable		 3n62B-2r4gA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7s PROBABLE CONSERVED
LIPOPROTEIN LPPA

(Mycobacterium
tuberculosis) 		PF16708
(LppA) 		4 GLN A  99
PHE A  92
ASN A 186
ASP A 102
 None
GOL  A1209 (-4.5A)
None
None
 1.23A 3n62B-2v7sA:
undetectable		 3n62B-2v7sA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w40 GLYCEROL KINASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASN A 391
GLN A 389
PHE A 388
ASN A 491
 None
 1.10A 3n62B-2w40A:
undetectable		 3n62B-2w40A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 SER A 311
ARG A  20
PHE A  19
ASN A 316
 None
 1.22A 3n62B-2y5wA:
undetectable		 3n62B-2y5wA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buz IOTA TOXIN COMPONENT
IA

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		4 SER A  50
GLN A 181
PHE A 136
ASN A  51
 None
 1.10A 3n62B-3buzA:
undetectable		 3n62B-3buzA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clw CONSERVED EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF14587
(Glyco_hydr_30_2) 		4 ARG A  52
GLN A 133
PHE A  55
ASN A 113
 None
 1.21A 3n62B-3clwA:
undetectable		 3n62B-3clwA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmg PUTATIVE
BETA-GALACTOSIDASE

(Bacteroides
fragilis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		4 ARG A 151
ASN A  86
ASN A 153
TRP A  68
 None
 1.21A 3n62B-3cmgA:
undetectable		 3n62B-3cmgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dal PR DOMAIN ZINC
FINGER PROTEIN 1

(Homo sapiens) 		PF00856
(SET) 		4 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.10A 3n62B-3dalA:
undetectable		 3n62B-3dalA:
19.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 266
ASN A 283
PHE A 286
TRP A 496
 AT2  A 906 (-3.6A)
None
None
None
 1.04A 3n62B-3e7gA:
57.4		 3n62B-3e7gA:
65.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ASN A 283
PHE A 286
ASN A 354
TRP A 496
 None
 1.04A 3n62B-3e7gA:
57.4		 3n62B-3e7gA:
65.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fzy RTX TOXIN RTXA

(Vibrio cholerae) 		PF11713
(Peptidase_C80) 		4 ARG A3530
GLN A3582
PHE A3579
ASP A3537
 None
 1.30A 3n62B-3fzyA:
undetectable		 3n62B-3fzyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 SER B 744
ARG B 747
ASN B 741
ASP B 907
 None
 1.10A 3n62B-3hkzB:
undetectable		 3n62B-3hkzB:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN REGULATORY
LIGHT CHAIN LC-2,
MANTLE MUSCLE

(Todarodes
pacificus) 		PF13405
(EF-hand_6) 		4 ASN B 138
GLN B 136
PHE B 137
ASP B  95
 None
 1.27A 3n62B-3i5gB:
undetectable		 3n62B-3i5gB:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASN A 384
GLN A 382
ASN A 523
TRP A 515
 None
 1.06A 3n62B-3ihvA:
undetectable		 3n62B-3ihvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ij3 CYTOSOL
AMINOPEPTIDASE

(Coxiella
burnetii) 		PF00883
(Peptidase_M17) 		4 ARG A 122
ASN A 117
ASN A 154
ASP A 151
 None
 1.23A 3n62B-3ij3A:
undetectable		 3n62B-3ij3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ij6 UNCHARACTERIZED
METAL-DEPENDENT
HYDROLASE

(Lactobacillus
acidophilus) 		PF04909
(Amidohydro_2) 		4 ASN A 281
GLN A 274
ASN A  53
ASP A  51
 None
 1.24A 3n62B-3ij6A:
undetectable		 3n62B-3ij6A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ix1 N-FORMYL-4-AMINO-5-A
MINOMETHYL-2-METHYLP
YRIMIDINE BINDING
PROTEIN

(Bacillus
halodurans) 		PF09084
(NMT1) 		5 SER A 109
ARG A 112
ASN A 289
PHE A 294
TRP A 239
 None
 1.37A 3n62B-3ix1A:
undetectable		 3n62B-3ix1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kie CAPSID PROTEIN VP1

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.21A 3n62B-3kieA:
undetectable		 3n62B-3kieA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mos TRANSKETOLASE

(Homo sapiens) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 SER A 345
ARG A 318
GLN A 428
ASN A 344
 None
 1.13A 3n62B-3mosA:
undetectable		 3n62B-3mosA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otx ADENOSINE KINASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00294
(PfkB) 		4 SER A 167
ASN A  13
ASN A 195
ASP A 299
 None
AP5  A 346 (-4.1A)
None
AP5  A 346 ( 3.2A)
 1.04A 3n62B-3otxA:
undetectable		 3n62B-3otxA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ra2 CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 SER A 393
ASN A 384
GLN A 388
PHE A 276
 None
 1.27A 3n62B-3ra2A:
undetectable		 3n62B-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t24 PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 SER A 123
ARG A 124
GLN A 128
ASP A 285
 SO4  A 397 (-2.4A)
SO4  A 397 ( 3.7A)
None
None
 1.18A 3n62B-3t24A:
undetectable		 3n62B-3t24A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3to3 PETROBACTIN
BIOSYNTHESIS PROTEIN
ASBB

(Bacillus
anthracis) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 ASN A 175
GLN A 171
PHE A 170
ASN A 303
 None
 1.14A 3n62B-3to3A:
undetectable		 3n62B-3to3A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ux1 CAPSID PROTEIN VP1

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.22A 3n62B-3ux1A:
undetectable		 3n62B-3ux1A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbz LIKELY HISTIDYL
TRNA-SPECIFIC
GUANYLYLTRANSFERASE

(Candida
albicans) 		PF04446
(Thg1)
PF14413
(Thg1C) 		4 ARG A 143
GLN A 150
PHE A 146
ASN A 144
 None
 1.32A 3n62B-3wbzA:
undetectable		 3n62B-3wbzA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw7 GH86A
BETA-PORPHYRANASE

(Bacteroides
plebeius) 		no annotation 4 ARG A 249
ASN A 253
PHE A 555
ASP A 208
 None
 1.32A 3n62B-4aw7A:
undetectable		 3n62B-4aw7A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0k PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3-LIKE PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 SER B 538
ARG B 540
GLN B 484
ASN B 523
 None
 1.25A 3n62B-4d0kB:
undetectable		 3n62B-4d0kB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 ASN B 912
GLN B 980
PHE B 979
ASP B 973
 None
 1.03A 3n62B-4f92B:
undetectable		 3n62B-4f92B:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr6 ATRBCX2

(Arabidopsis
thaliana) 		PF02341
(RcbX) 		4 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.17A 3n62B-4gr6A:
undetectable		 3n62B-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ine PROTEIN PMT-2

(Caenorhabditis
elegans) 		PF08241
(Methyltransf_11) 		4 SER A 257
ARG A 179
GLN A 115
ASN A 258
 None
 1.19A 3n62B-4ineA:
undetectable		 3n62B-4ineA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kem MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Azospirillum
lipoferum) 		PF13378
(MR_MLE_C) 		4 ASN A 265
GLN A 289
ASN A  19
ASP A 212
 None
None
CL  A 402 (-4.7A)
MG  A 401 (-2.6A)
 1.28A 3n62B-4kemA:
undetectable		 3n62B-4kemA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m01 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		no annotation 4 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
GOL  A 602 (-3.3A)
 1.32A 3n62B-4m01A:
undetectable		 3n62B-4m01A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mdv ANNEXIN

(Schistosoma
mansoni) 		PF00191
(Annexin) 		4 ARG A 239
ASN A 243
GLN A 248
ASP A 218
 None
 1.02A 3n62B-4mdvA:
undetectable		 3n62B-4mdvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oi3 NICKEL RESPONSIVE
PROTEIN

(Streptomyces
coelicolor) 		PF14026
(DUF4242) 		4 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.08A 3n62B-4oi3A:
undetectable		 3n62B-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvi GH62 HYDROLASE

(Mycothermus
thermophilus) 		PF03664
(Glyco_hydro_62) 		4 ASN A  -6
GLN A  -2
PHE A  -3
TRP A  32
 None
 1.29A 3n62B-4pviA:
undetectable		 3n62B-4pviA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q38 PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24

(Actinoplanes
teichomyceticus) 		no annotation 4 SER A 212
ARG A 215
GLN A 180
PHE A 181
 None
 1.17A 3n62B-4q38A:
undetectable		 3n62B-4q38A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi4 CELLOBIOSE
DEHYDROGENASE

(Crassicarpon
hotsonii) 		PF00732
(GMC_oxred_N)
PF00734
(CBM_1)
PF05199
(GMC_oxred_C) 		4 ASN A 292
PHE A 548
ASN A 610
ASP A 547
 CD  A 909 (-4.6A)
None
None
None
 1.16A 3n62B-4qi4A:
undetectable		 3n62B-4qi4A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi6 CELLOBIOSE
DEHYDROGENASE

(Crassicarpon
hotsonii) 		PF00732
(GMC_oxred_N)
PF00734
(CBM_1)
PF05199
(GMC_oxred_C)
PF16010
(CDH-cyt) 		4 ASN A 292
PHE A 548
ASN A 610
ASP A 547
 None
 1.07A 3n62B-4qi6A:
undetectable		 3n62B-4qi6A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE SUBUNIT N

(Thermococcus
kodakarensis;
Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF01194
(RNA_pol_N) 		5 SER B 746
ARG B 749
PHE N   8
ASN B 743
ASP B 911
 None
 1.42A 3n62B-4qiwB:
undetectable		 3n62B-4qiwB:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3f SPLICEOSOMAL PROTEIN
CWC27

(Chaetomium
thermophilum) 		PF00160
(Pro_isomerase) 		4 SER A  77
ASN A 107
PHE A 108
TRP A  91
 None
 1.31A 3n62B-4r3fA:
undetectable		 3n62B-4r3fA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnx NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 ASN A  56
GLN A  49
ASN A 388
TRP A 368
 None
 1.29A 3n62B-4rnxA:
undetectable		 3n62B-4rnxA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rso CAPSID PROTEIN VP1

(Non-human
primate
Adeno-associated
virus) 		PF00740
(Parvo_coat) 		4 SER A 392
ASN A 383
GLN A 387
PHE A 275
 None
 1.21A 3n62B-4rsoA:
undetectable		 3n62B-4rsoA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uac CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-)

([Eubacterium]
rectale) 		PF13416
(SBP_bac_8) 		4 GLN A 394
PHE A 189
ASN A 191
ASP A 190
 EDO  A 504 (-3.3A)
None
ACR  A 501 (-3.3A)
EDO  A 504 ( 4.2A)
 1.10A 3n62B-4uacA:
undetectable		 3n62B-4uacA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wh3 N-ACETYLHEXOSAMINE
1-KINASE

(Bifidobacterium
longum) 		PF01636
(APH) 		4 SER A 244
GLN A 131
PHE A 241
ASP A 240
 None
 1.27A 3n62B-4wh3A:
undetectable		 3n62B-4wh3A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzz TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		4 GLN A 264
PHE A 267
ASN A 149
TRP A 256
 None
 1.26A 3n62B-4yzzA:
undetectable		 3n62B-4yzzA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a08 PROBABLE
MANNOSYLTRANSFERASE
KTR4

(Saccharomyces
cerevisiae) 		PF01793
(Glyco_transf_15) 		4 PHE A 241
ASN A 172
ASP A 173
TRP A 204
 None
 1.29A 3n62B-5a08A:
undetectable		 3n62B-5a08A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aex AMMONIUM TRANSPORTER
MEP2

(Saccharomyces
cerevisiae) 		PF00909
(Ammonium_transp) 		4 SER A 116
ASN A 174
PHE A  89
ASP A 122
 None
 1.17A 3n62B-5aexA:
undetectable		 3n62B-5aexA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 GLN A 202
PHE A  67
ASN A  38
ASP A  76
 None
 1.16A 3n62B-5bnzA:
undetectable		 3n62B-5bnzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb2 YFIR

(Pseudomonas
aeruginosa) 		PF13689
(DUF4154) 		4 SER A 168
ARG A 171
PHE A 127
ASN A 165
 None
 1.19A 3n62B-5eb2A:
undetectable		 3n62B-5eb2A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqn FRBJ

(Streptomyces
rubellomurinus) 		PF02668
(TauD) 		4 ARG A 203
GLN A 115
ASP A 152
TRP A 311
 None
None
MG  A 401 (-3.5A)
None
 1.05A 3n62B-5eqnA:
undetectable		 3n62B-5eqnA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5haf DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.30A 3n62B-5hafA:
undetectable		 3n62B-5hafA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hnz PROTEIN CLARET
SEGREGATIONAL,PROTEI
N CLARET
SEGREGATIONAL,PLUS-E
ND DIRECTED
KINESIN-1/KINESIN-14
,PROTEIN CLARET
SEGREGATIONAL,PROTEI
N CLARET
SEGREGATIONAL

(Drosophila
melanogaster;
Rattus
norvegicus) 		PF00225
(Kinesin) 		4 SER K 319
ARG K  32
PHE K  31
ASN K 324
 None
 1.19A 3n62B-5hnzK:
undetectable		 3n62B-5hnzK:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5imw INTERMEDILYSIN

(Streptococcus
intermedius) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 SER A 119
ARG A 254
ASN A 252
ASP A 226
 None
 1.07A 3n62B-5imwA:
undetectable		 3n62B-5imwA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5imy VAGINOLYSIN

(Gardnerella
vaginalis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 SER A 133
PHE A 121
ASN A 126
ASP A 124
 None
 1.28A 3n62B-5imyA:
undetectable		 3n62B-5imyA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kxj L-ASPARTATE OXIDASE

(Salmonella
enterica) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A 208
ASN A 241
GLN A 242
PHE A 243
 None
 1.25A 3n62B-5kxjA:
undetectable		 3n62B-5kxjA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lii MAJOR CAPSID PROTEIN

(Staphylococcus
phage 812) 		no annotation 4 ASN P 247
GLN P 237
ASN P 242
ASP P 241
 None
 1.23A 3n62B-5liiP:
undetectable		 3n62B-5liiP:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lt1 KINESIN-LIKE PROTEIN

(Homo sapiens) 		PF00225
(Kinesin) 		4 SER A 303
ARG A  16
PHE A  15
ASN A 308
 None
 1.26A 3n62B-5lt1A:
undetectable		 3n62B-5lt1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979

(Staphylococcus
aureus) 		PF01832
(Glucosaminidase)
PF05257
(CHAP) 		4 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.12A 3n62B-5t1qA:
undetectable		 3n62B-5t1qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4y SUSC HOMOLOG

(Bacteroides
thetaiotaomicron) 		no annotation 4 SER D 343
ASN D 309
GLN D 307
ASN D 366
 None
 1.08A 3n62B-5t4yD:
undetectable		 3n62B-5t4yD:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.23A 3n62B-5tpwB:
undetectable		 3n62B-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubw DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.24A 3n62B-5ubwA:
undetectable		 3n62B-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrb TRANSKETOLASE

(Neisseria
gonorrhoeae) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ASN A 305
GLN A 310
PHE A 308
ASN A  53
 None
 1.31A 3n62B-5vrbA:
undetectable		 3n62B-5vrbA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3f TUBULIN ALPHA-1
CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 SER A 224
GLN A  15
PHE A 225
ASN A 227
 None
None
GTP  A 502 (-3.8A)
None
 1.09A 3n62B-5w3fA:
undetectable		 3n62B-5w3fA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xb6 UNCHARACTERIZED
PROTEIN YCJY

(Escherichia
coli) 		no annotation 4 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.03A 3n62B-5xb6A:
undetectable		 3n62B-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg VACUOLAR PROTEIN 8
NUCLEUS-VACUOLE
JUNCTION PROTEIN 1

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00514
(Arm)
no annotation 		4 SER A 280
ARG A 242
GLN B 308
ASN B 304
 None
 0.87A 3n62B-5xjgA:
undetectable		 3n62B-5xjgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE

(Streptococcus
pneumoniae) 		no annotation 4 ARG M 240
ASN M  56
GLN M  54
ASN M 242
 None
 1.06A 3n62B-5xu1M:
undetectable		 3n62B-5xu1M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ASN A 450
GLN A 130
ASN A 310
ASP A 308
 None
 1.17A 3n62B-5yh5A:
undetectable		 3n62B-5yh5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE DELTA
SUBUNIT

(Trypanosoma
brucei) 		no annotation 4 SER H 106
ARG H  34
ASN H 102
ASP H 108
 None
 1.26A 3n62B-6f5dH:
undetectable		 3n62B-6f5dH:
undetectable