SIMILAR PATTERNS OF AMINO ACIDS FOR 3N3I_A_ROCA201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dms DMSO REDUCTASE

(Rhodobacter
capsulatus)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
4 ILE A 484
PRO A 119
ASP A  35
GLY A  11
None
0.95A 3n3iA-1dmsA:
0.0
3n3iA-1dmsA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu1 DIMETHYL SULFOXIDE
REDUCTASE


(Rhodobacter
sphaeroides)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
4 ILE A 484
PRO A 119
ASP A  35
GLY A  11
None
0.87A 3n3iA-1eu1A:
0.0
3n3iA-1eu1A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3


(Rattus
norvegicus)
PF06325
(PrmA)
4 ILE A 265
ILE A 310
GLY A 260
VAL A 256
SAH  A 529 (-4.9A)
SAH  A 529 (-4.3A)
SAH  A 529 (-3.1A)
None
0.73A 3n3iA-1f3lA:
0.0
3n3iA-1f3lA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f56 PLANTACYANIN

(Spinacia
oleracea)
PF02298
(Cu_bind_like)
4 ILE A  63
ILE A  30
GLY A  59
VAL A  11
None
0.77A 3n3iA-1f56A:
0.0
3n3iA-1f56A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpe PROTEIN (GLUCOSE
OXIDASE)


(Penicillium
amagasakiense)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
4 ILE A 248
ASP A  82
ILE A 110
GLY A 106
None
None
None
FAD  A 600 (-3.0A)
0.90A 3n3iA-1gpeA:
0.0
3n3iA-1gpeA:
15.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ILE A  47
PRO A  81
ASP A  30
GLY A  49
VAL A  82
A79  A 800 ( 3.2A)
A79  A 800 ( 3.9A)
A79  A 800 ( 4.7A)
A79  A 800 (-3.4A)
A79  A 800 (-4.5A)
0.41A 3n3iA-1hvcA:
32.9
3n3iA-1hvcA:
95.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ILE A  47
PRO A  81
ASP A  30
GLY A  49
VAL A  82
A79  A 800 ( 3.4A)
A79  A 800 ( 3.4A)
A79  A 800 ( 4.9A)
A79  A 800 ( 3.7A)
A79  A 800 (-4.5A)
0.54A 3n3iA-1hvcA:
32.9
3n3iA-1hvcA:
95.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ILE A  47
PRO A  81
ASP A  30
ILE A  47
GLY A  49
A79  A 800 ( 3.4A)
A79  A 800 ( 3.4A)
A79  A 800 ( 4.9A)
A79  A 800 ( 3.2A)
A79  A 800 ( 3.7A)
0.67A 3n3iA-1hvcA:
32.9
3n3iA-1hvcA:
95.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ILE A  47
PRO A  81
ILE A  47
GLY A  49
VAL A  82
A79  A 800 ( 3.2A)
A79  A 800 ( 3.9A)
A79  A 800 ( 3.4A)
A79  A 800 (-3.4A)
A79  A 800 (-4.5A)
0.63A 3n3iA-1hvcA:
32.9
3n3iA-1hvcA:
95.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idj PECTIN LYASE A

(Aspergillus
niger)
PF00544
(Pec_lyase_C)
4 ILE A 135
ASP A  29
ILE A  28
VAL A  23
None
0.96A 3n3iA-1idjA:
0.0
3n3iA-1idjA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum)
PF05034
(MAAL_N)
PF07476
(MAAL_C)
4 ILE A 341
ILE A  53
GLY A 133
VAL A  72
None
0.94A 3n3iA-1kczA:
0.0
3n3iA-1kczA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi)
PF00365
(PFK)
4 ILE A 205
PRO A 435
ILE A  91
GLY A  87
None
0.63A 3n3iA-1kzhA:
0.0
3n3iA-1kzhA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldn L-LACTATE
DEHYDROGENASE


(Geobacillus
stearothermophilus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ILE A 159
ASP A  88
GLY A 131
VAL A  25
None
0.98A 3n3iA-1ldnA:
undetectable
3n3iA-1ldnA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE


(Pseudomonas
putida)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 ILE A  49
ASP A 346
ILE A 188
VAL A 342
None
0.83A 3n3iA-1lvlA:
undetectable
3n3iA-1lvlA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1npc NEUTRAL PROTEASE

(Bacillus cereus)
PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C)
4 ILE A 169
ASP A 181
ILE A 138
GLY A 142
None
0.75A 3n3iA-1npcA:
undetectable
3n3iA-1npcA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvt SHIKIMATE
5'-DEHYDROGENASE


(Methanocaldococcus
jannaschii)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N)
4 ILE A  14
PRO A 272
GLY A 260
VAL A  95
None
0.88A 3n3iA-1nvtA:
undetectable
3n3iA-1nvtA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4z BETA-AGARASE B

(Zobellia
galactanivorans)
PF00722
(Glyco_hydro_16)
4 ILE A 347
ILE A 261
GLY A 248
VAL A 342
None
0.95A 3n3iA-1o4zA:
undetectable
3n3iA-1o4zA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5z FOLYLPOLYGLUTAMATE
SYNTHASE/DIHYDROFOLA
TE SYNTHASE


(Thermotoga
maritima)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M)
4 ILE A 178
ILE A  45
GLY A  47
VAL A 221
None
None
SO4  A 501 (-4.5A)
None
0.98A 3n3iA-1o5zA:
undetectable
3n3iA-1o5zA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 TRIMETHYLAMINE
DEHYDROGENASE


(Methylophilus
methylotrophus)
PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2)
4 ILE A 695
ASP A 674
GLY A 688
VAL A 395
None
ADP  A1731 (-3.2A)
None
ADP  A1731 (-4.7A)
0.99A 3n3iA-1o94A:
undetectable
3n3iA-1o94A:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa1 HYDROXYLAMINE
REDUCTASE


(Desulfovibrio
vulgaris)
PF03063
(Prismane)
4 ILE A 367
PRO A 363
GLY A 234
VAL A 229
None
None
None
GOL  A1556 ( 3.5A)
0.86A 3n3iA-1oa1A:
undetectable
3n3iA-1oa1A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p99 HYPOTHETICAL PROTEIN
PG110


(Staphylococcus
aureus)
PF03180
(Lipoprotein_9)
4 ILE A 110
ILE A  69
GLY A  44
VAL A 256
None
0.96A 3n3iA-1p99A:
undetectable
3n3iA-1p99A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjq SIROHEME SYNTHASE

(Salmonella
enterica)
PF00590
(TP_methylase)
PF10414
(CysG_dimeriser)
PF13241
(NAD_binding_7)
PF14824
(Sirohm_synth_M)
4 ILE A 282
ILE A 306
GLY A 308
VAL A 221
None
ACT  A 505 (-3.6A)
None
None
0.95A 3n3iA-1pjqA:
undetectable
3n3iA-1pjqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5d P450 EPOXIDASE

(Sorangium
cellulosum)
PF00067
(p450)
4 ILE A 119
PRO A 154
GLY A 255
VAL A 364
None
None
HEM  A 440 (-3.3A)
None
0.90A 3n3iA-1q5dA:
undetectable
3n3iA-1q5dA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpg 3-PHOSPHOGLYCERATE
KINASE


(Saccharomyces
cerevisiae)
PF00162
(PGK)
4 ILE A 208
PRO A 280
ILE A 254
GLY A 235
None
None
None
MAP  A 450 (-3.5A)
0.97A 3n3iA-1qpgA:
undetectable
3n3iA-1qpgA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT


(Halothiobacillus
neapolitanus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 ILE A  35
ILE A 294
GLY A 301
VAL A 131
None
0.97A 3n3iA-1svdA:
undetectable
3n3iA-1svdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0t INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE


(Mycobacterium
tuberculosis)
PF01513
(NAD_kinase)
4 ILE A 218
PRO A 232
ASP A 189
VAL A 254
None
0.98A 3n3iA-1u0tA:
undetectable
3n3iA-1u0tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbf 231AA LONG
HYPOTHETICAL
PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE


(Sulfurisphaera
tokodaii)
PF01135
(PCMT)
4 ILE A  88
ASP A 124
ILE A 100
GLY A  78
None
0.75A 3n3iA-1vbfA:
undetectable
3n3iA-1vbfA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT


(Corynebacterium
sp. U-96)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4)
4 ASP A 951
ILE A 932
GLY A 928
VAL A 947
None
0.99A 3n3iA-1vrqA:
undetectable
3n3iA-1vrqA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xov PLY PROTEIN

(Listeria virus
PSA)
PF01520
(Amidase_3)
4 ILE A  49
ASP A  19
GLY A  16
VAL A 142
None
None
GLU  A2001 ( 3.7A)
None
0.94A 3n3iA-1xovA:
undetectable
3n3iA-1xovA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xsa BIS(5'-NUCLEOSYL)-TE
TRAPHOSPHATASE


(Homo sapiens)
PF00293
(NUDIX)
4 ILE A  70
PRO A  45
ILE A  97
GLY A  12
None
0.98A 3n3iA-1xsaA:
undetectable
3n3iA-1xsaA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybm UNKNOWN PROTEIN
AT5G02240


(Arabidopsis
thaliana)
PF13460
(NAD_binding_10)
4 ILE A  19
ILE A  57
GLY A  11
VAL A 129
None
NAP  A 400 (-3.7A)
NAP  A 400 ( 3.8A)
None
0.90A 3n3iA-1ybmA:
undetectable
3n3iA-1ybmA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeu HYPOTHETICAL PROTEIN
MJ0158


(Methanocaldococcus
jannaschii)
PF03841
(SelA)
4 ILE A 312
ILE A 328
GLY A 319
VAL A 300
None
0.84A 3n3iA-2aeuA:
undetectable
3n3iA-2aeuA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D


(Methanothermobacter
thermautotrophicus)
PF00710
(Asparaginase)
4 ILE A 347
ASP A 407
GLY A 354
VAL A 304
None
0.95A 3n3iA-2d6fA:
undetectable
3n3iA-2d6fA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus)
PF00063
(Myosin_head)
PF00612
(IQ)
4 ILE A 159
ASP A 229
ILE A 235
VAL A 183
None
0.91A 3n3iA-2dfsA:
undetectable
3n3iA-2dfsA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ls6 HYALURONOGLUCOSAMINI
DASE


(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
4 ILE A 141
ASP A 155
ILE A  47
GLY A  71
None
0.98A 3n3iA-2ls6A:
undetectable
3n3iA-2ls6A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(Aspergillus
oryzae)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 PRO A 358
ILE A  47
GLY A  49
VAL A  87
None
0.83A 3n3iA-2ps2A:
undetectable
3n3iA-2ps2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdx MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
PUTATIVE


(Roseovarius
nubinhibens)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ILE A 266
ASP A 355
GLY A 297
VAL A  36
None
0.90A 3n3iA-2rdxA:
undetectable
3n3iA-2rdxA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5i SALMONELLA
TYPHIMURIUM DB7155
BACTERIOPHAGE DET7
TAILSPIKE


(unidentified
phage)
PF09251
(PhageP22-tail)
4 ILE A 344
ASP A 437
GLY A 403
VAL A 379
None
0.93A 3n3iA-2v5iA:
undetectable
3n3iA-2v5iA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxy CELL DIVISION
PROTEIN FTSZ


(Bacillus
subtilis)
PF00091
(Tubulin)
PF12327
(FtsZ_C)
4 ILE A 298
ASP A 213
ILE A 293
GLY A 295
None
0.87A 3n3iA-2vxyA:
undetectable
3n3iA-2vxyA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster)
PF03159
(XRN_N)
4 ILE A  39
PRO A  46
GLY A 230
VAL A 238
None
0.96A 3n3iA-2y35A:
undetectable
3n3iA-2y35A:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster)
PF03159
(XRN_N)
4 ILE A 817
ILE A1138
GLY A 826
VAL A1052
None
0.96A 3n3iA-2y35A:
undetectable
3n3iA-2y35A:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv2 SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN


(Aeropyrum
pernix)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
4 ILE A 182
PRO A 136
ILE A 176
VAL A 237
None
0.76A 3n3iA-2yv2A:
undetectable
3n3iA-2yv2A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkj [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 4


(Homo sapiens)
PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3)
4 ILE A 372
ILE A 362
GLY A 346
VAL A 244
None
0.98A 3n3iA-2zkjA:
undetectable
3n3iA-2zkjA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agf GLUTAMINASE 1

(Bacillus
subtilis)
PF04960
(Glutaminase)
4 ILE A 109
ILE A 132
GLY A 128
VAL A 194
None
0.99A 3n3iA-3agfA:
undetectable
3n3iA-3agfA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asm RIBONUCLEASE HIII

(Geobacillus
stearothermophilus)
PF01351
(RNase_HII)
PF11858
(DUF3378)
4 ILE A 146
ILE A 201
GLY A  95
VAL A  99
None
0.95A 3n3iA-3asmA:
undetectable
3n3iA-3asmA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b7f GLYCOSYL HYDROLASE,
BNR REPEAT


(Cupriavidus
pinatubonensis)
no annotation 4 ILE A 181
PRO A 185
ASP A 258
ILE A 245
None
None
EDO  A 402 (-3.5A)
None
0.91A 3n3iA-3b7fA:
undetectable
3n3iA-3b7fA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvd PROTECTIVE ANTIGEN

(Bacillus
anthracis)
PF03495
(Binary_toxB)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3)
4 ILE A 707
ILE A 676
GLY A 641
VAL A 655
None
0.92A 3n3iA-3hvdA:
undetectable
3n3iA-3hvdA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3n KELCH-LIKE PROTEIN
11


(Homo sapiens)
PF00651
(BTB)
PF07707
(BACK)
4 ILE A  96
PRO A 124
ASP A 181
VAL A 154
None
0.98A 3n3iA-3i3nA:
undetectable
3n3iA-3i3nA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ino PROTECTIVE ANTIGEN
PA-63


(Bacillus
anthracis)
no annotation 4 ILE A 707
ILE A 676
GLY A 641
VAL A 655
None
0.98A 3n3iA-3inoA:
undetectable
3n3iA-3inoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kje CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE
COMPLEX, ACCESSORY
PROTEIN COOC


(Carboxydothermus
hydrogenoformans)
PF01656
(CbiA)
4 ILE A 183
ASP A  39
GLY A 142
VAL A 160
None
0.91A 3n3iA-3kjeA:
undetectable
3n3iA-3kjeA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kwe CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN


(Thermosynechococcus
elongatus)
PF00132
(Hexapep)
4 ILE A 141
PRO A 168
ILE A 175
VAL A  98
None
0.96A 3n3iA-3kweA:
undetectable
3n3iA-3kweA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ly1 PUTATIVE
HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE


(Pectobacterium
atrosepticum)
PF00155
(Aminotran_1_2)
4 ILE A 370
ASP A 228
ILE A 197
GLY A 195
None
0.80A 3n3iA-3ly1A:
undetectable
3n3iA-3ly1A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3meb ASPARTATE
AMINOTRANSFERASE


(Giardia
intestinalis)
PF00155
(Aminotran_1_2)
4 ILE A 364
ASP A 382
GLY A 397
VAL A 420
None
0.88A 3n3iA-3mebA:
undetectable
3n3iA-3mebA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwt NUCLEOPROTEIN

(Lassa
mammarenavirus)
PF00843
(Arena_nucleocap)
PF17290
(Arena_ncap_C)
4 ILE A 326
ILE A 241
GLY A 177
VAL A 113
None
0.89A 3n3iA-3mwtA:
undetectable
3n3iA-3mwtA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R


(Ectromelia
virus)
PF00047
(ig)
PF13895
(Ig_2)
4 ILE B   7
ASP B  22
ILE B 119
GLY B  34
None
0.98A 3n3iA-3oq3B:
undetectable
3n3iA-3oq3B:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qde CELLOBIOSE
PHOSPHORYLASE


(Ruminiclostridium
thermocellum)
PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36)
4 ILE A 783
ILE A 732
GLY A 734
VAL A 776
None
0.99A 3n3iA-3qdeA:
undetectable
3n3iA-3qdeA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC


(Abies grandis)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
4 ILE A 669
ASP A 579
ILE A 657
GLY A 661
None
0.85A 3n3iA-3s9vA:
undetectable
3n3iA-3s9vA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wqo UNCHARACTERIZED
PROTEIN MJ1311


(Methanocaldococcus
jannaschii)
PF01261
(AP_endonuc_2)
4 ILE A 156
ILE A 251
GLY A 215
VAL A 256
None
0.91A 3n3iA-3wqoA:
undetectable
3n3iA-3wqoA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zla NUCLEOPROTEIN

(Bunyamwera
orthobunyavirus)
PF00952
(Bunya_nucleocap)
4 ILE A  39
PRO A 125
GLY A  46
VAL A  72
None
U  I  19 ( 3.9A)
U  I  18 ( 4.7A)
None
0.77A 3n3iA-3zlaA:
undetectable
3n3iA-3zlaA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apm APICAL MEMBRANE
ANTIGEN 1


(Babesia
divergens)
PF02430
(AMA-1)
4 ILE A 116
PRO A 438
ASP A 240
GLY A 142
None
0.97A 3n3iA-4apmA:
undetectable
3n3iA-4apmA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4atf BETA-AGARASE B

(Zobellia
galactanivorans)
PF00722
(Glyco_hydro_16)
4 ILE A 347
ILE A 261
GLY A 248
VAL A 342
None
0.92A 3n3iA-4atfA:
undetectable
3n3iA-4atfA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ghb HYPOTHETICAL PROTEIN

(Bacteroides
uniformis)
PF15283
(DUF4595)
4 ILE A 164
PRO A  58
ILE A 245
GLY A 251
None
0.80A 3n3iA-4ghbA:
undetectable
3n3iA-4ghbA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hp8 2-DEOXY-D-GLUCONATE
3-DEHYDROGENASE


(Agrobacterium
fabrum)
PF13561
(adh_short_C2)
4 ILE A  50
ILE A 137
GLY A  22
VAL A 223
None
NAP  A 301 (-4.5A)
None
None
0.91A 3n3iA-4hp8A:
undetectable
3n3iA-4hp8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifd EXOSOME COMPLEX
COMPONENT RRP43


(Saccharomyces
cerevisiae)
PF01138
(RNase_PH)
4 ILE C 274
ILE C  91
GLY C  93
VAL C 282
None
0.58A 3n3iA-4ifdC:
undetectable
3n3iA-4ifdC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iig BETA-GLUCOSIDASE 1

(Aspergillus
aculeatus)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 ILE A 392
ILE A 466
GLY A 579
VAL A 590
None
0.83A 3n3iA-4iigA:
undetectable
3n3iA-4iigA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnd CA(2+)/CALMODULIN-DE
PENDENT PROTEIN
KINASE PHOSPHATASE


(Caenorhabditis
elegans)
PF00481
(PP2C)
4 ILE A 404
ILE A 269
GLY A 422
VAL A 265
None
0.97A 3n3iA-4jndA:
undetectable
3n3iA-4jndA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jyp HYDROLASE,
ALPHA/BETA FOLD
FAMILY PROTEIN


(Arabidopsis
thaliana)
PF12697
(Abhydrolase_6)
4 ILE A 100
ASP A  60
GLY A  53
VAL A   4
None
0.83A 3n3iA-4jypA:
undetectable
3n3iA-4jypA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina)
PF00704
(Glyco_hydro_18)
PF16403
(DUF5011)
4 ILE A 101
ASP A  30
GLY A 108
VAL A  34
None
0.89A 3n3iA-4mb5A:
undetectable
3n3iA-4mb5A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9x PUTATIVE
MONOOXYGENASE


(Pectobacterium
atrosepticum)
PF01494
(FAD_binding_3)
4 ILE A  29
ASP A 289
GLY A  10
VAL A 285
None
0.92A 3n3iA-4n9xA:
undetectable
3n3iA-4n9xA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oon PENICILLIN-BINDING
PROTEIN 1A


(Pseudomonas
aeruginosa)
PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB)
4 ILE A 526
PRO A 552
ASP A 704
GLY A 560
None
0.97A 3n3iA-4oonA:
undetectable
3n3iA-4oonA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE


(Bradyrhizobium
diazoefficiens)
PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg)
4 ILE A 591
PRO A 824
ILE A 835
GLY A 598
None
0.98A 3n3iA-4q73A:
undetectable
3n3iA-4q73A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhm ARGINASE

(Trypanosoma
brucei)
PF00491
(Arginase)
4 ILE A 264
ASP A 237
GLY A 124
VAL A 227
None
0.99A 3n3iA-4rhmA:
undetectable
3n3iA-4rhmA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr1 GLUTAREDOXIN 3

(Alkaliphilus
oremlandii)
PF00462
(Glutaredoxin)
4 ILE A  77
ASP A  28
GLY A  83
VAL A  56
None
0.92A 3n3iA-4tr1A:
undetectable
3n3iA-4tr1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd3 L-AMINO ACID LIGASE

(Bacillus
subtilis)
PF13535
(ATP-grasp_4)
4 ILE A 282
PRO A 100
GLY A 263
VAL A 215
None
0.93A 3n3iA-4wd3A:
undetectable
3n3iA-4wd3A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjv RIBOSOME ASSEMBLY
PROTEIN 4


(Saccharomyces
cerevisiae)
PF00400
(WD40)
4 ILE A 363
PRO A 239
GLY A 287
VAL A 375
None
0.87A 3n3iA-4wjvA:
undetectable
3n3iA-4wjvA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE


(Sulfolobus
acidocaldarius)
no annotation 4 ASP A 220
ILE A 182
GLY A 180
VAL A 207
None
0.83A 3n3iA-5a7tA:
undetectable
3n3iA-5a7tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cov NAEGLERIA GRUBERI
RNA LIGASE


(Naegleria
gruberi)
PF09414
(RNA_ligase)
4 ILE A 328
PRO A 124
ILE A 233
VAL A 281
None
0.93A 3n3iA-5covA:
undetectable
3n3iA-5covA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ew5 COLICIN-E9

(Escherichia
coli)
PF03515
(Cloacin)
4 ILE A 156
ASP A 164
GLY A  91
VAL A 200
None
0.94A 3n3iA-5ew5A:
undetectable
3n3iA-5ew5A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 ILE A 393
ILE A 467
GLY A 580
VAL A 591
None
0.80A 3n3iA-5fjjA:
undetectable
3n3iA-5fjjA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA


(Escherichia
coli)
PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6)
4 ILE A 101
ILE A  65
GLY A  67
VAL A 271
None
0.94A 3n3iA-5fkuA:
undetectable
3n3iA-5fkuA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6


(Homo sapiens)
PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition)
4 ASP A 387
ILE A 344
GLY A 558
VAL A 433
None
0.91A 3n3iA-5gjeA:
undetectable
3n3iA-5gjeA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT DELTA


(Saccharomyces
cerevisiae)
PF00118
(Cpn60_TCP1)
4 ILE d 321
ASP d 211
GLY d 327
VAL d 197
None
0.95A 3n3iA-5gw5d:
undetectable
3n3iA-5gw5d:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h60 TRANSFERASE

(Escherichia
coli)
no annotation 4 ILE A 259
PRO A 284
ASP A 130
ILE A 175
None
0.82A 3n3iA-5h60A:
undetectable
3n3iA-5h60A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iqj UNCHARACTERIZED
PROTEIN


(Vibrio cholerae)
no annotation 4 ILE A  69
ILE A  59
GLY A  63
VAL A  20
None
0.95A 3n3iA-5iqjA:
undetectable
3n3iA-5iqjA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iwx 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE


(Bacillus
subtilis)
PF02542
(YgbB)
4 ILE A 100
PRO A 104
ASP A 112
ILE A  24
None
0.87A 3n3iA-5iwxA:
undetectable
3n3iA-5iwxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jfc NADH-DEPENDENT
FERREDOXIN:NADP
OXIDOREDUCTASE
SUBUNIT ALPHA
NADH-DEPENDENT
FERREDOXIN:NADP
OXIDOREDUCTASE
SUBUNIT BETA


(Pyrococcus
furiosus)
PF07992
(Pyr_redox_2)
PF10418
(DHODB_Fe-S_bind)
PF14691
(Fer4_20)
4 ILE L 400
ILE L 194
GLY L 196
VAL S 222
None
None
FAD  L 503 ( 4.3A)
FES  S 501 (-4.9A)
0.88A 3n3iA-5jfcL:
undetectable
3n3iA-5jfcL:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lji FLAVODOXIN

(Streptococcus
pneumoniae)
PF00258
(Flavodoxin_1)
4 ILE A  18
ILE A  84
GLY A  86
VAL A  33
None
0.94A 3n3iA-5ljiA:
undetectable
3n3iA-5ljiA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mn5 CELL DIVISION
PROTEIN FTSZ


(Staphylococcus
aureus)
PF00091
(Tubulin)
PF12327
(FtsZ_C)
4 ILE A 298
ASP A 213
ILE A 293
GLY A 295
None
0.96A 3n3iA-5mn5A:
undetectable
3n3iA-5mn5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT B


(Methanothermobacter
sp. CaT2)
PF00384
(Molybdopterin)
4 PRO B 345
ASP B 414
ILE B 365
VAL B 101
None
MGD  B 503 (-3.0A)
MGD  B 503 (-4.9A)
None
0.88A 3n3iA-5t5iB:
undetectable
3n3iA-5t5iB:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens)
no annotation 4 ILE A 502
ILE A 190
GLY A  88
VAL A 454
None
0.87A 3n3iA-5vanA:
undetectable
3n3iA-5vanA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi9 -

(-)
no annotation 4 ILE A 502
ILE A 190
GLY A  88
VAL A 454
None
0.88A 3n3iA-5wi9A:
undetectable
3n3iA-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x68 KYNURENINE
3-MONOOXYGENASE


(Homo sapiens)
no annotation 4 ILE A  34
ASP A 304
GLY A  15
VAL A 300
None
FAD  A 401 (-2.6A)
FAD  A 401 (-3.5A)
None
0.87A 3n3iA-5x68A:
undetectable
3n3iA-5x68A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT


(Komagataella
phaffii)
PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
4 ILE A 524
PRO A 520
GLY A 629
VAL A 613
None
0.93A 3n3iA-5xogA:
undetectable
3n3iA-5xogA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT


(Methylobacillus
sp. KY4400)
no annotation 4 ILE A 146
ILE C 745
GLY C 678
VAL C 711
None
0.90A 3n3iA-5y6qA:
undetectable
3n3iA-5y6qA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zb8 PFUENDOQ

(Pyrococcus
furiosus)
no annotation 4 ILE A 341
PRO A 304
ASP A 193
GLY A 203
None
None
ZN  A 502 (-2.5A)
None
0.97A 3n3iA-5zb8A:
undetectable
3n3iA-5zb8A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blk SIGNAL TRANSDUCTION
HISTIDINE-PROTEIN
KINASE/PHOSPHATASE
MPRB


(Mycolicibacterium
hassiacum)
no annotation 4 ILE C 393
ILE C 359
GLY C 473
VAL C 444
None
0.78A 3n3iA-6blkC:
undetectable
3n3iA-6blkC:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE


(Moorella
thermoacetica)
no annotation 4 ILE A 961
ASP A 994
ILE A1070
VAL A 818
None
0.94A 3n3iA-6cipA:
undetectable
3n3iA-6cipA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus)
no annotation 4 ILE A2521
ILE A2167
GLY A2515
VAL A2507
None
0.86A 3n3iA-6fb3A:
undetectable
3n3iA-6fb3A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fn1 HUMAN-MOUSE CHIMERIC
ABCB1 (ABCBHM)


(Homo sapiens)
no annotation 4 PRO A  65
ILE A  59
GLY A  61
VAL A 132
None
0.87A 3n3iA-6fn1A:
undetectable
3n3iA-6fn1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5


(Mus musculus)
no annotation 4 ILE M 412
ASP L 179
ILE M 400
GLY M 404
None
0.99A 3n3iA-6g2jM:
undetectable
3n3iA-6g2jM:
20.44