SIMILAR PATTERNS OF AMINO ACIDS FOR 3N23_A_OBNA1_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bvu | PROTEIN (GLUTAMATEDEHYDROGENASE) (Thermococcuslitoralis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ASP A 326VAL A 313ALA A 314PHE A 340THR A 321 | None | 1.23A | 3n23A-1bvuA:0.0 | 3n23A-1bvuA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ckr | HEAT SHOCK SUBSTRATEBINDING DOMAIN OFHSC-70 (Rattusnorvegicus) |
PF00012(HSP70) | 5 | ASP A 531ASN A 537VAL A 474THR A 409ILE A 401 | None | 1.33A | 3n23A-1ckrA:0.0 | 3n23A-1ckrA:11.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cm8 | PHOSPHORYLATED MAPKINASE P38-GAMMA (Homo sapiens) |
PF00069(Pkinase) | 5 | PRO A 353ASP A 91VAL A 53ALA A 44ILE A 55 | None | 1.39A | 3n23A-1cm8A:0.0 | 3n23A-1cm8A:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddg | SULFITE REDUCTASE(NADPH) FLAVOPROTEINALPHA-COMPONENT (Escherichiacoli) |
PF00175(NAD_binding_1)PF00667(FAD_binding_1) | 5 | PRO A 490ASP A 495ASN A 489THR A 248ILE A 247 | None | 1.42A | 3n23A-1ddgA:3.0 | 3n23A-1ddgA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ee2 | ALCOHOLDEHYDROGENASE (Equus caballus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | PRO A 248VAL A 261PHE A 197ILE A 219ARG A 270 | NoneNoneNoneNoneNAD A1100 (-4.4A) | 1.41A | 3n23A-1ee2A:5.2 | 3n23A-1ee2A:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gng | FRATTIDEGLYCOGEN SYNTHASEKINASE-3 BETA (Homo sapiens) |
PF00069(Pkinase)PF05350(GSK-3_bind) | 5 | VAL X 217ALA X 216PHE A 257THR A 275ILE X 213 | None | 1.27A | 3n23A-1gngX:undetectable | 3n23A-1gngX:3.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1guz | MALATE DEHYDROGENASE (Chlorobaculumtepidum;Prosthecochlorisvibrioformis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 39PRO A 38ASP A 32VAL A 101ILE A 97 | NoneNoneNAD A1306 (-3.0A)NoneNAD A1306 (-3.8A) | 1.13A | 3n23A-1guzA:3.6 | 3n23A-1guzA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gv0 | MALATE DEHYDROGENASE (Chlorobaculumtepidum) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 39PRO A 38ASP A 32VAL A 101ILE A 97 | NoneNoneNAD A1306 (-3.1A)NoneNAD A1306 (-4.1A) | 1.15A | 3n23A-1gv0A:undetectable | 3n23A-1gv0A:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hl2 | N-ACETYLNEURAMINATELYASE SUBUNIT (Escherichiacoli) |
PF00701(DHDPS) | 5 | ASP A 191VAL A 242PHE A 252THR A 209ILE A 212 | None | 1.10A | 3n23A-1hl2A:undetectable | 3n23A-1hl2A:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jae | ALPHA-AMYLASE (Tenebriomolitor) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 5 | ASP A 284ASN A 288PHE A 328PHE A 326THR A 298 | None | 1.43A | 3n23A-1jaeA:undetectable | 3n23A-1jaeA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qox | BETA-GLUCOSIDASE (Bacilluscirculans) |
PF00232(Glyco_hydro_1) | 5 | GLN A 20ASN A 165THR A 354ILE A 293ARG A 375 | None | 1.37A | 3n23A-1qoxA:undetectable | 3n23A-1qoxA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1soj | CGMP-INHIBITED3',5'-CYCLICPHOSPHODIESTERASE B (Homo sapiens) |
PF00233(PDEase_I) | 5 | VAL A 685PHE A 679THR A 743ILE A 740ARG A 755 | None | 1.36A | 3n23A-1sojA:undetectable | 3n23A-1sojA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sr4 | CYTOLETHALDISTENDING TOXINPROTEIN B ([Haemophilus]ducreyi) |
PF03372(Exo_endo_phos) | 5 | ASP B 244ALA B 240PHE B 27ILE B 224ARG B 126 | None | 1.25A | 3n23A-1sr4B:undetectable | 3n23A-1sr4B:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uf2 | CORE PROTEIN P3 (Rice dwarfvirus) |
PF09231(RDV-p3) | 5 | GLN A 395PRO A 508ASN A 412ALA A 499THR A 502 | None | 1.28A | 3n23A-1uf2A:undetectable | 3n23A-1uf2A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uxi | MALATE DEHYDROGENASE (Chloroflexusaurantiacus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 40PRO A 39ASP A 33ALA A 101ILE A 98 | NoneNoneNAD A1310 (-3.0A)NAD A1310 ( 4.4A)NAD A1310 (-4.1A) | 1.29A | 3n23A-1uxiA:undetectable | 3n23A-1uxiA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v7v | CHITOBIOSEPHOSPHORYLASE (Vibrioproteolyticus) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 5 | GLN A 674ASN A 670VAL A 719ALA A 718THR A 321 | None | 1.20A | 3n23A-1v7vA:undetectable | 3n23A-1v7vA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xpo | RHO TRANSCRIPTIONTERMINATION FACTOR (Escherichiacoli) |
PF00006(ATP-synt_ab)PF07497(Rho_RNA_bind)PF07498(Rho_N) | 5 | ASP A 328ALA A 317THR A 268ILE A 267ARG A 212 | NoneNoneNoneNoneAGS A1600 ( 3.2A) | 1.42A | 3n23A-1xpoA:2.9 | 3n23A-1xpoA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fkn | UROCANATE HYDRATASE (Bacillussubtilis) |
PF01175(Urocanase)PF17391(Urocanase_N)PF17392(Urocanase_C) | 5 | PRO A 449VAL A 326ALA A 327PHE A 336ILE A 323 | None | 1.38A | 3n23A-2fknA:undetectable | 3n23A-2fknA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fn9 | RIBOSE ABCTRANSPORTER,PERIPLASMICRIBOSE-BINDINGPROTEIN (Thermotogamaritima) |
PF13407(Peripla_BP_4) | 5 | PRO A 144ASN A 106VAL A 273PHE A 16ILE A 102 | None | 1.30A | 3n23A-2fn9A:2.2 | 3n23A-2fn9A:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gw1 | MITOCHONDRIALPRECURSOR PROTEINSIMPORT RECEPTOR (Saccharomycescerevisiae) |
PF00515(TPR_1)PF13181(TPR_8)PF13432(TPR_16) | 5 | ASN A 212ALA A 569PHE A 565THR A 583ILE A 582 | None | 1.29A | 3n23A-2gw1A:undetectable | 3n23A-2gw1A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixb | ALPHA-N-ACETYLGALACTOSAMINIDASE (Elizabethkingiameningoseptica) |
PF01408(GFO_IDH_MocA) | 5 | VAL A 48ALA A 49PHE A 25ILE A 92ARG A 31 | NoneNoneNoneNoneNAD A1445 (-3.4A) | 1.12A | 3n23A-2ixbA:2.5 | 3n23A-2ixbA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2g | DIENELACTONEHYDROLASE (Trichormusvariabilis) |
PF01738(DLH) | 5 | PRO A 108ASP A 109ASN A 107VAL A 14ALA A 13 | NoneNoneNoneEDO A 225 (-4.9A)EDO A 225 (-3.7A) | 1.41A | 3n23A-2o2gA:undetectable | 3n23A-2o2gA:13.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocd | L-ASPARAGINASE I (Vibrio cholerae) |
PF00710(Asparaginase) | 5 | ASP A 73ALA A 100PHE A 105PHE A 203ILE A 208 | None | 1.43A | 3n23A-2ocdA:undetectable | 3n23A-2ocdA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjz | HYPOTHETICAL PROTEINST1066 (Sulfurisphaeratokodaii) |
PF00005(ABC_tran) | 5 | PRO A 155ASP A 153ASN A 79ALA A 49THR A 44 | NoneNoneNoneNoneSO4 A 502 (-3.7A) | 1.28A | 3n23A-2pjzA:undetectable | 3n23A-2pjzA:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETA (Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | ASN B 191VAL B 204PHE B 365ILE B 206ARG B 366 | SRM B 503 ( 3.5A)NoneNoneNoneNone | 1.22A | 3n23A-2v4jB:undetectable | 3n23A-2v4jB:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsq | SURFACTIN SYNTHETASESUBUNIT 3 (Bacillussubtilis) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 5 | PRO A 600ASP A 599ASN A 500VAL A 474ALA A 473 | None | 1.28A | 3n23A-2vsqA:undetectable | 3n23A-2vsqA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkp | NPH1-1, RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 5 | ASP A 471ASN A 472VAL A 476PHE A 509ILE A 466 | NoneNoneNoneNoneFMN A1725 (-4.2A) | 1.14A | 3n23A-2wkpA:undetectable | 3n23A-2wkpA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkp | NPH1-1, RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 5 | ASP A 471VAL A 476PHE A 509ILE A 466ARG A 421 | NoneNoneNoneFMN A1725 (-4.2A)None | 1.03A | 3n23A-2wkpA:undetectable | 3n23A-2wkpA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wmc | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Pisum sativum) |
PF01652(IF4E) | 5 | ASP A 142VAL A 170ALA A 108PHE A 110PHE A 61 | None | 1.35A | 3n23A-2wmcA:undetectable | 3n23A-2wmcA:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y0e | UDP-GLUCOSEDEHYDROGENASE (Burkholderiacepacia) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | VAL A 84ALA A 83PHE A 27ILE A 82ARG A 65 | None | 1.23A | 3n23A-2y0eA:undetectable | 3n23A-2y0eA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypd | PROBABLE JMJCDOMAIN-CONTAININGHISTONEDEMETHYLATION PROTEIN 2C (Homo sapiens) |
PF02373(JmjC) | 5 | GLN A2476ASN A2470VAL A2323PHE A2367ARG A2379 | EMT A3503 (-4.8A)NoneNoneNoneNone | 1.33A | 3n23A-2ypdA:undetectable | 3n23A-2ypdA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0f | XYLOGLUCANASE (Geotrichum sp.M128) |
no annotation | 5 | GLN A 699PRO A 695VAL A 739ALA A 751ILE A 741 | None | 1.42A | 3n23A-3a0fA:undetectable | 3n23A-3a0fA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqc | COMPONENT B OFHEXAPRENYLDIPHOSPHATE SYNTHASE (Micrococcusluteus) |
PF00348(polyprenyl_synt) | 5 | ASP B 212VAL B 278ALA B 243PHE B 160THR B 237 | None | 1.29A | 3n23A-3aqcB:undetectable | 3n23A-3aqcB:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bh1 | UPF0371 PROTEINDIP2346 (Corynebacteriumdiphtheriae) |
PF08903(DUF1846) | 5 | PRO A 212ASN A 237VAL A 333ALA A 330ILE A 306 | None | 1.27A | 3n23A-3bh1A:undetectable | 3n23A-3bh1A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo7 | PUTATIVENITROREDUCTASE (Trichormusvariabilis) |
PF00881(Nitroreductase) | 5 | PRO A 100ASP A 187VAL A 165ALA A 232ILE A 231 | FMN A 700 (-4.1A)FMN A 700 (-4.4A)NoneNoneNone | 1.40A | 3n23A-3eo7A:undetectable | 3n23A-3eo7A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hgo | 12-OXOPHYTODIENOATEREDUCTASE 3 (Solanumlycopersicum) |
PF00724(Oxidored_FMN) | 5 | GLN A 162VAL A 225PHE A 195ILE A 184ARG A 203 | None | 1.29A | 3n23A-3hgoA:undetectable | 3n23A-3hgoA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iq0 | PUTATIVE RIBOKINASEII (Escherichiacoli) |
PF00294(PfkB) | 5 | PRO A 166ASP A 165ALA A 263PHE A 260ARG A 227 | NoneATP A 900 ( 4.3A)NoneATP A 900 (-4.2A)None | 1.29A | 3n23A-3iq0A:3.7 | 3n23A-3iq0A:15.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kln | TRANSCRIPTIONALREGULATOR, LUXRFAMILY (Vibrio cholerae) |
PF00196(GerE) | 5 | GLN A 92VAL A 86ALA A 106ILE A 125ARG A 134 | None | 1.18A | 3n23A-3klnA:undetectable | 3n23A-3klnA:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lb5 | HIT-LIKE PROTEININVOLVED INCELL-CYCLEREGULATION (Bartonellahenselae) |
PF01230(HIT) | 5 | PRO A 41ASN A 132VAL A 24ALA A 32ILE A 73 | None | 1.40A | 3n23A-3lb5A:undetectable | 3n23A-3lb5A:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nep | MALATE DEHYDROGENASE (Salinibacterruber) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN X 60PRO X 59ASP X 53VAL X 123ILE X 119 | None | 1.17A | 3n23A-3nepX:undetectable | 3n23A-3nepX:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3orw | PHOSPHOTRIESTERASE (Geobacilluskaustophilus) |
PF02126(PTE) | 5 | ALA A 167PHE A 109THR A 96ILE A 144ARG A 112 | NoneNoneNoneKCX A 145 ( 4.1A)None | 1.28A | 3n23A-3orwA:undetectable | 3n23A-3orwA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0t | UNCHARACTERIZEDPROTEIN (Mycobacteriumavium) |
PF01230(HIT) | 5 | PRO A 32VAL A 71ALA A 70THR A 38ILE A 67 | None | 1.29A | 3n23A-3p0tA:undetectable | 3n23A-3p0tA:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poc | ALPHA-GLUCOSIDASE (Blautia obeum) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 5 | PRO A 75ASP A 73VAL A 270ALA A 269ILE A 313 | None | 1.32A | 3n23A-3pocA:undetectable | 3n23A-3pocA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3u | LIGNIN PEROXIDASE (Trametopsiscervina) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 5 | ASP A 282VAL A 272ALA A 271PHE A 128PHE A 111 | None | 1.43A | 3n23A-3q3uA:undetectable | 3n23A-3q3uA:15.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8i | PURINE NUCLEOSIDASE,(IUNH-2) (Sulfolobussolfataricus) |
PF01156(IU_nuc_hydro) | 5 | ASP A 7ASN A 126ALA A 171PHE A 162ILE A 146 | NoneNoneNoneGOL A 310 (-4.6A)None | 1.42A | 3n23A-3t8iA:4.5 | 3n23A-3t8iA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3td9 | BRANCHED CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Thermotogamaritima) |
PF13458(Peripla_BP_6) | 5 | ASP A 306VAL A 132ALA A 344THR A 326ILE A 338 | None | 1.34A | 3n23A-3td9A:3.3 | 3n23A-3td9A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttl | POLYAMINE TRANSPORTPROTEIN (Pseudomonasaeruginosa) |
PF13416(SBP_bac_8) | 5 | PRO A 162VAL A 235ALA A 236PHE A 175ILE A 137 | None | 1.21A | 3n23A-3ttlA:undetectable | 3n23A-3ttlA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uog | ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ASN A 43VAL A 178ALA A 179ILE A 241ARG A 330 | None | 1.14A | 3n23A-3uogA:5.3 | 3n23A-3uogA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1n | CARBON MONOXIDEDEHYDROGENASECORRINOID/IRON-SULFUR PROTEIN, GAMMASUBUNIT (Carboxydothermushydrogenoformans) |
PF03599(CdhD)PF04060(FeS) | 5 | GLN A 244PRO A 232ASP A 231ALA A 132ILE A 161 | None | 1.35A | 3n23A-4c1nA:undetectable | 3n23A-4c1nA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c30 | DNA HELICASE II (Deinococcusradiodurans) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | GLN A 588PRO A 592ALA A 299PHE A 327ILE A 615 | None | 1.34A | 3n23A-4c30A:undetectable | 3n23A-4c30A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djt | GTP-BINDING NUCLEARPROTEIN GSP1 (Encephalitozooncuniculi) |
PF00071(Ras) | 5 | ALA A 166PHE A 162PHE A 158ILE A 57ARG A 26 | None | 1.35A | 3n23A-4djtA:undetectable | 3n23A-4djtA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htt | SEC-INDEPENDENTPROTEIN TRANSLOCASEPROTEIN TATC,LYSOZYME (Aquifexaeolicus;Escherichiavirus T4) |
PF00902(TatC) | 5 | PRO A 42VAL A 71ALA A 70PHE A 152ILE A 67 | None | 1.28A | 3n23A-4httA:undetectable | 3n23A-4httA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hw6 | HYPOTHETICALPROTEIN, IPT/TIGDOMAIN PROTEIN (Bacteroidesovatus) |
PF01833(TIG) | 5 | VAL A 332ALA A 319PHE A 391ILE A 310ARG A 400 | None | 1.38A | 3n23A-4hw6A:undetectable | 3n23A-4hw6A:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4maa | PUTATIVEBRANCHED-CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Pseudomonasprotegens) |
PF13458(Peripla_BP_6) | 5 | ASP A 130ALA A 186PHE A 230THR A 148ILE A 152 | NoneNoneGOL A 503 ( 4.8A)NoneNone | 1.28A | 3n23A-4maaA:2.1 | 3n23A-4maaA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nd4 | LACTATEDEHYDROGENASE,ADJACENT GENEENCODES PREDICTEDMALATE DEHYDROGENASE (Cryptosporidiumparvum) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 60PRO A 59ASP A 53VAL A 123ILE A 119 | NoneNoneNAD A 401 (-2.7A)NoneNAD A 401 (-3.9A) | 1.26A | 3n23A-4nd4A:undetectable | 3n23A-4nd4A:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng4 | PHOSPHOGLYCERATEKINASE (Coxiellaburnetii) |
PF00162(PGK) | 5 | PRO A 168ASP A 142VAL A 57ALA A 109ILE A 59 | None | 1.24A | 3n23A-4ng4A:5.2 | 3n23A-4ng4A:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ntc | GLIT (Aspergillusfumigatus) |
PF07992(Pyr_redox_2) | 5 | VAL A 16ALA A 39THR A 28ILE A 18ARG A 80 | None | 1.36A | 3n23A-4ntcA:undetectable | 3n23A-4ntcA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4onq | DNAMETHYLTRANSFERASE (Nicotianatabacum) |
PF00145(DNA_methylase) | 5 | PRO A 369ASP A 368VAL A 393ALA A 392ILE A 389 | None | 0.98A | 3n23A-4onqA:undetectable | 3n23A-4onqA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9k | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Verminephrobactereiseniae) |
PF03480(DctP) | 5 | PRO A 105ALA A 327PHE A 323PHE A 319ILE A 331 | None | 1.34A | 3n23A-4p9kA:undetectable | 3n23A-4p9kA:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pdx | PUTATIVEALKYL/ARYL-SULFATASEYJCS (Escherichiacoli) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 5 | GLN A 127ASP A 149PHE A 298PHE A 282THR A 179 | None | 1.41A | 3n23A-4pdxA:undetectable | 3n23A-4pdxA:22.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phs | PUTATIVEGLYCOSYLTRANSFERASE(GALT1) (Streptococcusparasanguinis) |
PF08759(GT-D) | 5 | GLN A 57ASP A 210ALA A 176PHE A 177ILE A 183 | NoneNoneUDP A 301 (-3.3A)NoneNone | 1.38A | 3n23A-4phsA:undetectable | 3n23A-4phsA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plf | LACTATEDEHYDROGENASE (Apicomplexa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 46PRO A 45ASP A 39VAL A 113ILE A 109 | NoneNoneNAI A 401 (-2.2A)NoneNAI A 401 (-3.7A) | 1.20A | 3n23A-4plfA:undetectable | 3n23A-4plfA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plh | MALATE DEHYDROGENASE (Apicomplexa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 42PRO A 41ASP A 35VAL A 104ILE A 100 | NoneNoneNAI A 403 (-2.8A)NoneNAI A 403 (-3.7A) | 1.17A | 3n23A-4plhA:undetectable | 3n23A-4plhA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zn6 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Acinetobacterbaumannii) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | GLN A 11VAL A 158ALA A 132THR A 26ILE A 22 | None | 1.35A | 3n23A-4zn6A:undetectable | 3n23A-4zn6A:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoh | PUTATIVEOXIDOREDUCTASEMOLYBDOPTERIN-BINDING SUBUNIT (Sulfurisphaeratokodaii) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | GLN A 562PRO A 662ASP A 381ILE A 412ARG A 485 | None | 1.27A | 3n23A-4zohA:undetectable | 3n23A-4zohA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ahm | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Pseudomonasaeruginosa) |
PF00478(IMPDH) | 5 | ASP A 337ASN A 276VAL A 245ILE A 69ARG A 456 | IMP A 501 (-2.6A)IMP A 501 ( 4.3A)NoneNoneNone | 1.21A | 3n23A-5ahmA:undetectable | 3n23A-5ahmA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 5 | GLN A 184PRO A 182VAL A 562ALA A 563ILE A 586 | None | 1.41A | 3n23A-5d0fA:undetectable | 3n23A-5d0fA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 5 | VAL A1365PHE A1360PHE A1356ILE A1362ARG A1337 | None | 1.41A | 3n23A-5d0fA:undetectable | 3n23A-5d0fA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dju | NPH1-2 (Avena sativa) |
PF13426(PAS_9) | 5 | ASP A 471ASN A 472VAL A 476PHE A 509ILE A 466 | NoneNoneNoneNoneFMN A 601 ( 4.4A) | 1.18A | 3n23A-5djuA:undetectable | 3n23A-5djuA:8.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dju | NPH1-2 (Avena sativa) |
PF13426(PAS_9) | 5 | ASP A 471VAL A 476PHE A 509ILE A 466ARG A 421 | NoneNoneNoneFMN A 601 ( 4.4A)None | 1.13A | 3n23A-5djuA:undetectable | 3n23A-5djuA:8.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9g | ISOCITRATE LYASE (Magnaportheoryzae) |
PF00463(ICL) | 5 | ASP A 323ASN A 326VAL A 362ALA A 357ILE A 365 | None | 1.25A | 3n23A-5e9gA:undetectable | 3n23A-5e9gA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITBETA TYPE (Plasmodiumfalciparum) |
PF00227(Proteasome) | 5 | VAL L 16ALA L 15PHE L 126THR L 44ILE L 34 | None | 1.31A | 3n23A-5fmgL:undetectable | 3n23A-5fmgL:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fzo | PROBABLE JMJCDOMAIN-CONTAININGHISTONEDEMETHYLATION PROTEIN 2C (Homo sapiens) |
PF02373(JmjC) | 5 | GLN A2476ASN A2470VAL A2323PHE A2367ARG A2379 | None | 1.36A | 3n23A-5fzoA:undetectable | 3n23A-5fzoA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hr6 | RLMN METHYLASE (Escherichiacoli) |
PF04055(Radical_SAM) | 5 | ASP A 34VAL A 74ALA A 75ILE A 18ARG A 25 | None | 1.11A | 3n23A-5hr6A:undetectable | 3n23A-5hr6A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hw3 | BETA-LACTAMASE (Burkholderiavietnamiensis) |
PF13354(Beta-lactamase2) | 5 | PRO A 33VAL A 260ALA A 259ILE A 220ARG A 56 | None | 1.27A | 3n23A-5hw3A:undetectable | 3n23A-5hw3A:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzh | RAS-RELATED C3BOTULINUM TOXINSUBSTRATE1,NPH1-1,RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 5 | ASP A 118ASN A 119VAL A 123PHE A 156ILE A 113 | NoneNoneNoneFMN A 402 (-4.9A)FMN A 402 (-4.3A) | 1.20A | 3n23A-5hzhA:undetectable | 3n23A-5hzhA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzh | RAS-RELATED C3BOTULINUM TOXINSUBSTRATE1,NPH1-1,RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 5 | ASP A 118VAL A 123PHE A 156ILE A 113ARG A 68 | NoneNoneFMN A 402 (-4.9A)FMN A 402 (-4.3A)None | 1.35A | 3n23A-5hzhA:undetectable | 3n23A-5hzhA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzk | INTERSECTIN-1,NPH1-1,INTERSECTIN-1 (Avena sativa;Homo sapiens) |
PF00621(RhoGEF)PF13426(PAS_9)PF16652(PH_13) | 5 | ASP B1376ASN B1377VAL B1381PHE B1414ILE B1371 | NoneNoneNoneFMN B1801 (-4.8A)FMN B1801 (-4.1A) | 1.25A | 3n23A-5hzkB:undetectable | 3n23A-5hzkB:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzk | INTERSECTIN-1,NPH1-1,INTERSECTIN-1 (Avena sativa;Homo sapiens) |
PF00621(RhoGEF)PF13426(PAS_9)PF16652(PH_13) | 5 | ASP B1376VAL B1381PHE B1414ILE B1371ARG B1326 | NoneNoneFMN B1801 (-4.8A)FMN B1801 (-4.1A)None | 1.31A | 3n23A-5hzkB:undetectable | 3n23A-5hzkB:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF00623(RNA_pol_Rpb1_2)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | GLN A 650ASP A 526ASN A 654PHE A 482ILE B1011 | None | 1.14A | 3n23A-5ip9A:undetectable | 3n23A-5ip9A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jh8 | PROBABLE CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 5 | ASN A 93VAL A 82ALA A 81THR A 34ILE A 78 | None | 1.14A | 3n23A-5jh8A:undetectable | 3n23A-5jh8A:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks1 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Vibriovulnificus) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | GLN A 2VAL A 149ALA A 123THR A 17ILE A 13 | None | 1.26A | 3n23A-5ks1A:undetectable | 3n23A-5ks1A:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | GLN A1620VAL A1695ALA A1611THR A1598ILE A1602 | None | 1.42A | 3n23A-5m59A:undetectable | 3n23A-5m59A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msc | CARBOXYLIC ACIDREDUCTASE (Nocardiaiowensis) |
PF00501(AMP-binding) | 5 | GLN A 11VAL A 24ALA A 27THR A 338ILE A 291 | None | 1.21A | 3n23A-5mscA:3.3 | 3n23A-5mscA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6y | NITROGENASEVANADIUM-IRONPROTEIN BETA CHAIN (Azotobactervinelandii) |
no annotation | 5 | GLN E 181ASP E 244ASN E 247ALA E 176ILE E 173 | None | 1.40A | 3n23A-5n6yE:undetectable | 3n23A-5n6yE:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oc1 | ARYL-ALCOHOL OXIDASE (Pleurotuseryngii) |
no annotation | 5 | GLN A 176ALA A 358PHE A 320THR A 390ILE A 391 | NoneANN A 601 ( 4.9A)NoneNoneANN A 601 (-3.9A) | 1.43A | 3n23A-5oc1A:undetectable | 3n23A-5oc1A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ulv | MALATE DEHYDROGENASE (Methylobacteriumextorquens) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 41PRO A 40ASP A 34VAL A 103ALA A 102 | None | 1.03A | 3n23A-5ulvA:undetectable | 3n23A-5ulvA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wro | ENOLASE (Drosophilamelanogaster) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ASP A 158ASN A 159ALA A 424THR A 417ILE A 415 | None | 1.41A | 3n23A-5wroA:undetectable | 3n23A-5wroA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ws4 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Acinetobacterbaumannii) |
no annotation | 5 | GLN A 152PRO A 144ASN A 108VAL A 576ALA A 575 | None | 1.37A | 3n23A-5ws4A:undetectable | 3n23A-5ws4A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wuf | PUTATIVE MEMBRANEPROTEIN (Colwelliapsychrerythraea) |
PF03458(UPF0126) | 5 | VAL A 13ALA A 42THR A 72ILE A 69ARG A 26 | None | 1.39A | 3n23A-5wufA:undetectable | 3n23A-5wufA:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbc | NSP1 PROTEIN (Porcineepidemicdiarrhea virus) |
no annotation | 5 | ASP A 50VAL A 44ALA A 10THR A 51ILE A 15 | None | 1.25A | 3n23A-5xbcA:undetectable | 3n23A-5xbcA:6.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xe3 | ENDORIBONUCLEASEMAZF4 (Mycobacteriumtuberculosis) |
no annotation | 5 | PRO C 56ASP C 58VAL C 64THR C 88ILE C 92 | None | 1.33A | 3n23A-5xe3C:undetectable | 3n23A-5xe3C:9.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yrz | HICB (Streptococcuspneumoniae) |
no annotation | 5 | GLN A 34ASP A 12PHE A 86PHE A 80THR A 89 | None | 1.41A | 3n23A-5yrzA:undetectable | 3n23A-5yrzA:6.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ywz | SUNDOMAIN-CONTAININGPROTEIN 1 (Mus musculus) |
no annotation | 5 | GLN A 789PRO A 790ASP A 791THR A 692ILE A 691 | None | 0.93A | 3n23A-5ywzA:undetectable | 3n23A-5ywzA:5.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0t | FASCIN (Homo sapiens) |
no annotation | 5 | ASP A 192ALA A 153THR A 190ILE A 177ARG A 197 | None | 1.28A | 3n23A-6b0tA:undetectable | 3n23A-6b0tA:6.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byi | BETA-MANNOSIDASE (Xanthomonascitri) |
no annotation | 5 | ASN A 211VAL A 205PHE A 144THR A 126ARG A 462 | None | 1.39A | 3n23A-6byiA:undetectable | 3n23A-6byiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxh | PARTICULATE METHANEMONOOXYGENASE, BSUBUNIT (Methylomicrobiumalcaliphilum) |
no annotation | 5 | PRO A 280ALA A 315PHE A 392PHE A 50ILE A 394 | None | 1.32A | 3n23A-6cxhA:undetectable | 3n23A-6cxhA:6.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d21 | FERM, RHOGEF ANDPLECKSTRIN DOMAINPROTEIN 2 (Danio rerio) |
no annotation | 5 | GLN A 74ASP A 107VAL A 104PHE A 130ILE A 315 | None | 1.33A | 3n23A-6d21A:undetectable | 3n23A-6d21A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITALPHA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 5 | PRO C 159ASP C 155VAL C 179ALA C 180THR C 149 | None | 1.37A | 3n23A-6fkhC:undetectable | 3n23A-6fkhC:6.51 |