SIMILAR PATTERNS OF AMINO ACIDS FOR 3MJR_B_AC2B401
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2a30 | DEOXYCYTIDINE KINASE (Homo sapiens) |
PF01712(dNK) | 8 | ILE A 30GLU A 53PHE A 96GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137 | DCZ A 302 ( 4.3A)DCZ A 302 (-3.0A)DCZ A 302 (-4.6A)DCZ A 302 (-3.2A)NoneDCZ A 302 (-4.1A)DCZ A 302 (-3.2A)DCZ A 302 (-3.8A) | 0.71A | 3mjrB-2a30A:32.4 | 3mjrB-2a30A:92.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jaq | DEOXYGUANOSINEKINASE (Mycoplasmamycoides) |
PF01712(dNK) | 5 | GLN A 54ARG A 61ARG A 78ASP A 83PHE A 86 | DCP A1202 (-2.9A)NoneDCP A1202 (-2.8A)DCP A1202 (-3.6A)DCP A1202 (-3.6A) | 0.66A | 3mjrB-2jaqA:21.1 | 3mjrB-2jaqA:25.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jcs | DEOXYNUCLEOSIDEKINASE (Drosophilamelanogaster) |
PF01712(dNK) | 5 | ILE A 29PHE A 80GLN A 81ARG A 105PHE A 114 | TTP A1210 (-3.9A)TTP A1210 (-4.2A)TTP A1210 (-3.0A)TTP A1210 (-3.7A)TTP A1210 (-3.5A) | 0.74A | 3mjrB-2jcsA:23.3 | 3mjrB-2jcsA:28.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocp | DEOXYGUANOSINEKINASE (Homo sapiens) |
PF01712(dNK) | 5 | ILE A 47PHE A 110ARG A 142ASP A 147PHE A 151 | DTP A 301 (-3.8A)DTP A 301 (-4.2A)DTP A 301 (-3.2A)DTP A 301 (-4.1A)DTP A 301 (-3.3A) | 0.92A | 3mjrB-2ocpA:29.8 | 3mjrB-2ocpA:44.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocp | DEOXYGUANOSINEKINASE (Homo sapiens) |
PF01712(dNK) | 5 | ILE A 47PHE A 110GLN A 111ARG A 142PHE A 151 | DTP A 301 (-3.8A)DTP A 301 (-4.2A)DTP A 301 (-2.9A)DTP A 301 (-3.2A)DTP A 301 (-3.3A) | 0.63A | 3mjrB-2ocpA:29.8 | 3mjrB-2ocpA:44.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iay | DNA POLYMERASE DELTACATALYTIC SUBUNIT (Saccharomycescerevisiae) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | ILE A 348VAL A 142GLN A 290ARG A 428ASP A 394 | None | 1.29A | 3mjrB-3iayA:0.1 | 3mjrB-3iayA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH DEHYDROGENASE[UBIQUINONE] 1 ALPHASUBCOMPLEX SUBUNIT10, MITOCHONDRIAL (Mus musculus) |
no annotation | 5 | ILE O 31GLU O 53ARG O 126ASP O 131PHE O 134 | ADP O 401 (-4.0A)ADP O 401 ( 4.7A)ADP O 401 ( 4.3A)NoneADP O 401 (-3.6A) | 1.14A | 3mjrB-6g2jO:undetectable | 3mjrB-6g2jO:13.98 |