SIMILAR PATTERNS OF AMINO ACIDS FOR 3ME6_C_CGEC501
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqq | TYPE 2 RHINOVIRUS 3CPROTEASE (Rhinovirus A) |
PF00548(Peptidase_C3) | 5 | VAL A 30ILE A 90ALA A 172VAL A 150VAL A 157 | None | 1.25A | 3me6C-1cqqA:undetectable | 3me6C-1cqqA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ei6 | PHOSPHONOACETATEHYDROLASE (Pseudomonasfluorescens) |
PF01663(Phosphodiest) | 5 | ILE A 313PHE A 309ALA A 306VAL A 341VAL A 316 | None | 1.13A | 3me6C-1ei6A:0.0 | 3me6C-1ei6A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eth | TRIACYLGLYCEROLACYL-HYDROLASE (Sus scrofa) |
PF00151(Lipase)PF01477(PLAT) | 5 | VAL A 105PHE A 39ILE A 75ALA A 127VAL A 35 | None | 0.89A | 3me6C-1ethA:0.0 | 3me6C-1ethA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g7r | TRANSLATIONINITIATION FACTORIF2/EIF5B (Methanothermobacterthermautotrophicus) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF11987(IF-2)PF14578(GTP_EFTU_D4) | 5 | VAL A 366PHE A 429ILE A 407VAL A 375VAL A 353 | None | 1.08A | 3me6C-1g7rA:undetectable | 3me6C-1g7rA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hp1 | 5'-NUCLEOTIDASE (Escherichiacoli) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | VAL A 443ILE A 480ALA A 399VAL A 403VAL A 466 | None | 1.10A | 3me6C-1hp1A:undetectable | 3me6C-1hp1A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpl | LIPASE (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 5 | VAL A 104PHE A 38ILE A 74ALA A 126VAL A 34 | None | 1.07A | 3me6C-1hplA:0.0 | 3me6C-1hplA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i4g | ENTEROTOXIN TYPE A (Staphylococcusaureus) |
PF01123(Stap_Strp_toxin)PF02876(Stap_Strp_tox_C) | 5 | VAL A 143ALA A 187THR A 188VAL A 152VAL A 150 | None ZN A 460 ( 4.2A)NoneNoneNone | 1.19A | 3me6C-1i4gA:0.0 | 3me6C-1i4gA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j2q | PROTEASOME ALPHASUBUNIT (Archaeoglobusfulgidus) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 5 | VAL A 109ILE A 74ALA A 77VAL A 46VAL A 215 | None | 1.19A | 3me6C-1j2qA:undetectable | 3me6C-1j2qA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbv | MAJOR OUTER MEMBRANEPROTEIN PAN 1 (Neisseriagonorrhoeae) |
PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 5 | VAL A 41ILE A 72PHE A 98ALA A 101VAL A 74 | None | 1.21A | 3me6C-1kbvA:0.0 | 3me6C-1kbvA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1n | GENOME POLYPROTEIN:PICORNAIN 3C (Enterovirus C) |
PF00548(Peptidase_C3) | 5 | VAL A 30ILE A 90ALA A 172VAL A 150VAL A 157 | None | 1.22A | 3me6C-1l1nA:undetectable | 3me6C-1l1nA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpb | LIPASE (Homo sapiens) |
PF00151(Lipase)PF01477(PLAT) | 5 | VAL B 104PHE B 38ILE B 74ALA B 126VAL B 34 | None | 1.02A | 3me6C-1lpbB:undetectable | 3me6C-1lpbB:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mus | TN5 TRANSPOSASE (Escherichiacoli) |
PF01609(DDE_Tnp_1)PF02281(Dimer_Tnp_Tn5)PF14706(Tnp_DNA_bind) | 5 | VAL A 34ILE A 355PHE A 17ALA A 20VAL A 69 | None | 1.24A | 3me6C-1musA:undetectable | 3me6C-1musA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mus | TN5 TRANSPOSASE (Escherichiacoli) |
PF01609(DDE_Tnp_1)PF02281(Dimer_Tnp_Tn5)PF14706(Tnp_DNA_bind) | 5 | VAL A 34ILE A 355PHE A 17ALA A 77VAL A 69 | None | 1.12A | 3me6C-1musA:undetectable | 3me6C-1musA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o6e | CAPSID PROTEIN P40 (Humangammaherpesvirus4) |
PF00716(Peptidase_S21) | 5 | VAL A 54ILE A 142ALA A 107VAL A 7VAL A 9 | None | 1.02A | 3me6C-1o6eA:undetectable | 3me6C-1o6eA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p8a | PROTEIN TYROSINEPHOSPHATASE (Tritrichomonassuis) |
PF01451(LMWPc) | 5 | VAL A 106ILE A 94PHE A 77THR A 73VAL A 10 | None | 1.25A | 3me6C-1p8aA:undetectable | 3me6C-1p8aA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5n | 3-CARBOXY-CIS,CIS-MUCONATECYCLOISOMERASE (Acinetobactercalcoaceticus) |
PF00206(Lyase_1)PF10397(ADSL_C) | 6 | VAL A 372PHE A 426ALA A 396THR A 395VAL A 410VAL A 388 | None | 1.47A | 3me6C-1q5nA:undetectable | 3me6C-1q5nA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qvr | CLPB PROTEIN (Thermusthermophilus) |
PF00004(AAA)PF02861(Clp_N)PF07724(AAA_2)PF10431(ClpB_D2-small) | 5 | VAL A 182PHE A 268ILE A 303ALA A 206VAL A 329 | NoneNoneNoneANP A 901 (-3.2A)None | 1.13A | 3me6C-1qvrA:undetectable | 3me6C-1qvrA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w52 | PANCREATIC LIPASERELATED PROTEIN 2 (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 5 | VAL X 106PHE X 39ILE X 76ALA X 128VAL X 35 | None | 1.18A | 3me6C-1w52X:undetectable | 3me6C-1w52X:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w61 | B-CELL MITOGEN (Trypanosomacruzi) |
PF05544(Pro_racemase) | 5 | VAL A 268ILE A 213ALA A 306THR A 310VAL A 211 | None | 1.17A | 3me6C-1w61A:undetectable | 3me6C-1w61A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zch | HYPOTHETICALOXIDOREDUCTASE YCND (Bacillussubtilis) |
PF00881(Nitroreductase) | 5 | VAL A 48PHE A 79ILE A 31ALA A 125VAL A 75 | None | 1.05A | 3me6C-1zchA:undetectable | 3me6C-1zchA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cu5 | CONSERVEDHYPOTHETICAL PROTEINTT1486 (Thermusthermophilus) |
PF01894(UPF0047) | 5 | VAL A 111ILE A 19ALA A 25VAL A 126VAL A 124 | None | 1.22A | 3me6C-2cu5A:undetectable | 3me6C-2cu5A:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3f | GLYCOLIPIDTRANSFER-LIKEPROTEIN (Galdieriasulphuraria) |
PF08718(GLTP) | 5 | VAL A 45PHE A 12ILE A 107PHE A 176VAL A 115 | None | 1.25A | 3me6C-2i3fA:undetectable | 3me6C-2i3fA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocx | NODULATIONFUCOSYLTRANSFERASENODZ (Bradyrhizobiumsp. WM9) |
PF05830(NodZ) | 5 | VAL A 174ILE A 205ALA A 197VAL A 228VAL A 232 | None | 1.24A | 3me6C-2ocxA:undetectable | 3me6C-2ocxA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odr | PHOSPHOSERYL-TRNASYNTHETASE (Methanococcusmaripaludis) |
PF01409(tRNA-synt_2d) | 5 | PHE B 64PHE B 298ALA B 248VAL B 241VAL B 300 | None | 1.22A | 3me6C-2odrB:undetectable | 3me6C-2odrB:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q6d | INFECTIOUSBRONCHITIS VIRUS(IBV) MAIN PROTEASE (Aviancoronavirus) |
PF05409(Peptidase_C30) | 5 | VAL A 146PHE A 157ILE A 17ALA A 12VAL A 120 | None | 1.25A | 3me6C-2q6dA:undetectable | 3me6C-2q6dA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm0 | BES (Bacillus cereus) |
PF00756(Esterase) | 5 | VAL A 84PHE A 129ILE A 132PHE A 162ALA A 163 | None | 1.07A | 3me6C-2qm0A:undetectable | 3me6C-2qm0A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2re2 | UNCHARACTERIZEDPROTEIN TA1041 (Thermoplasmaacidophilum) |
PF02579(Nitro_FeMo-Co) | 5 | ILE A 98PHE A 3ALA A 4VAL A 12VAL A 86 | None | 1.11A | 3me6C-2re2A:undetectable | 3me6C-2re2A:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rsv | SERINE/THREONINE-PROTEIN KINASE VRK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 70ILE A 29PHE A 23ALA A 24VAL A 62 | None | 1.25A | 3me6C-2rsvA:undetectable | 3me6C-2rsvA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3y | VIRULENCE FACTOR (Pectobacteriumcarotovorum) |
no annotation | 5 | VAL A 243PHE A 239PHE A 191PHE A 106VAL A 10 | None | 1.21A | 3me6C-2w3yA:undetectable | 3me6C-2w3yA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlc | POLYSIALIC ACIDO-ACETYLTRANSFERASE (Neisseriameningitidis) |
PF00132(Hexapep) | 5 | VAL A 144PHE A 174ILE A 158ALA A 182VAL A 150 | None | 1.18A | 3me6C-2wlcA:undetectable | 3me6C-2wlcA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsh | ENDONUCLEASE II (Escherichiavirus T4) |
PF01541(GIY-YIG) | 5 | VAL A 90ILE A 39ALA A 78THR A 75VAL A 46 | None | 1.16A | 3me6C-2wshA:undetectable | 3me6C-2wshA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wym | L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG (Escherichiacoli) |
PF13483(Lactamase_B_3) | 5 | PHE A 38PHE A 280ILE A 48ALA A 245VAL A 60 | None | 1.26A | 3me6C-2wymA:undetectable | 3me6C-2wymA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzr | POLYPROTEIN (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | VAL 3 204PHE 3 81ALA 3 80VAL 3 185VAL 3 160 | None | 0.94A | 3me6C-2wzr3:undetectable | 3me6C-2wzr3:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | VAL A 194PHE A 489ILE A 41ALA A 48VAL A 35 | FAD A 600 ( 4.2A)NoneNoneNoneNone | 1.06A | 3me6C-2y3sA:undetectable | 3me6C-2y3sA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | VAL A 194PHE A 489ILE A 41ALA A 48VAL A 76 | FAD A 600 ( 4.2A)NoneNoneNoneNone | 1.23A | 3me6C-2y3sA:undetectable | 3me6C-2y3sA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zgh | GRANZYME M (Homo sapiens) |
PF00089(Trypsin) | 5 | VAL A 31ILE A 224ALA A 88VAL A 197VAL A 217 | None | 0.89A | 3me6C-2zghA:undetectable | 3me6C-2zghA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9x | SELENOCYSTEINE LYASE (Rattusnorvegicus) |
PF00266(Aminotran_5) | 5 | VAL A 179ILE A 197ALA A 170VAL A 154VAL A 163 | None | 1.17A | 3me6C-3a9xA:undetectable | 3me6C-3a9xA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqp | PROBABLE SECDFPROTEIN-EXPORTMEMBRANE PROTEIN (Thermusthermophilus) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 5 | VAL A 585PHE A 589ILE A 635THR A 672VAL A 716 | None | 1.04A | 3me6C-3aqpA:undetectable | 3me6C-3aqpA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efv | PUTATIVESUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
PF00171(Aldedh) | 5 | VAL A 196ILE A 200ALA A 218VAL A 210VAL A 208 | NAD A 463 (-4.2A)NoneNoneNoneNone | 1.15A | 3me6C-3efvA:undetectable | 3me6C-3efvA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i2w | SYNDAPIN (Drosophilamelanogaster) |
PF00611(FCH) | 5 | PHE A 241ILE A 111PHE A 242VAL A 249VAL A 107 | None | 1.25A | 3me6C-3i2wA:undetectable | 3me6C-3i2wA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ifr | CARBOHYDRATE KINASE,FGGY (Rhodospirillumrubrum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ILE A 167ALA A 227THR A 231VAL A 239VAL A 82 | None | 1.17A | 3me6C-3ifrA:undetectable | 3me6C-3ifrA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krv | HYDROLASE (Geobacillusstearothermophilus) |
PF04199(Cyclase) | 5 | VAL A 103PHE A 105ILE A 135ALA A 127THR A 157 | None | 1.16A | 3me6C-3krvA:undetectable | 3me6C-3krvA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kve | L-AMINO ACID OXIDASE (Viperaammodytes) |
PF01593(Amino_oxidase) | 5 | VAL A 292PHE A 454ILE A 302VAL A 271VAL A 273 | None | 1.24A | 3me6C-3kveA:undetectable | 3me6C-3kveA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lml | LIN1278 PROTEIN (Listeriainnocua) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 5 | PHE A 392ILE A 369PHE A 22ALA A 399VAL A 432 | None | 1.25A | 3me6C-3lmlA:undetectable | 3me6C-3lmlA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lno | PUTATIVEUNCHARACTERIZEDPROTEIN (Bacillusanthracis) |
PF01883(FeS_assembly_P) | 5 | VAL A 64ILE A 26ALA A 12VAL A 35VAL A 32 | None | 1.13A | 3me6C-3lnoA:undetectable | 3me6C-3lnoA:11.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnp | AMIDOHYDROLASEFAMILY PROTEINOLEI01672_1_465 (Oleispiraantarctica) |
PF01979(Amidohydro_1) | 5 | PHE A 146ALA A 163THR A 443VAL A 430VAL A 428 | None | 1.10A | 3me6C-3lnpA:undetectable | 3me6C-3lnpA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjz | FG41 MALONATESEMIALDEHYDEDECARBOXYLASE (coryneformbacterium) |
PF14552(Tautomerase_2) | 5 | VAL A 23ILE A 68THR A 8VAL A 97VAL A 102 | None | 1.13A | 3me6C-3mjzA:undetectable | 3me6C-3mjzA:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3plr | UDP-GLUCOSE6-DEHYDROGENASE (Klebsiellapneumoniae) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | PHE A 247ILE A 318ALA A 288VAL A 332VAL A 301 | None | 1.20A | 3me6C-3plrA:undetectable | 3me6C-3plrA:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxg | NEGATIVE REGULATOROF GENETICCOMPETENCE CLPC/MECB (Bacillussubtilis) |
PF00004(AAA)PF02151(UVR)PF02861(Clp_N) | 5 | VAL A 192PHE A 277ILE A 312ALA A 216VAL A 339 | None | 0.97A | 3me6C-3pxgA:undetectable | 3me6C-3pxgA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxi | NEGATIVE REGULATOROF GENETICCOMPETENCE CLPC/MECB (Bacillussubtilis) |
PF00004(AAA)PF02151(UVR)PF02861(Clp_N)PF07724(AAA_2)PF10431(ClpB_D2-small) | 5 | VAL A 192PHE A 277ILE A 312ALA A 216VAL A 339 | None | 0.97A | 3me6C-3pxiA:undetectable | 3me6C-3pxiA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qd7 | UNCHARACTERIZEDPROTEIN YDAL (Escherichiacoli) |
PF01713(Smr) | 5 | VAL X 138PHE X 105ILE X 119VAL X 148VAL X 166 | None | 1.18A | 3me6C-3qd7X:undetectable | 3me6C-3qd7X:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ry7 | RIBOKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 5 | VAL A 138PHE A 256ILE A 257ALA A 274VAL A 184 | None | 1.17A | 3me6C-3ry7A:undetectable | 3me6C-3ry7A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sks | PUTATIVEOLIGOENDOPEPTIDASE F (Bacillusanthracis) |
no annotation | 5 | VAL A 233PHE A 540ILE A 488ALA A 493VAL A 425 | None | 1.24A | 3me6C-3sksA:undetectable | 3me6C-3sksA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sno | HYPOTHETICALAMINOTRANSFERASE (Corynebacteriumglutamicum) |
PF01063(Aminotran_4) | 5 | PHE A 250ILE A 231ALA A 248VAL A 279VAL A 224 | None | 0.97A | 3me6C-3snoA:undetectable | 3me6C-3snoA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t1w | FOUR-DOMAINFIBRONECTIN FRAGMENT (Homo sapiens) |
PF00041(fn3) | 5 | VAL A1414ILE A1407ALA A1403VAL A1427VAL A1429 | None | 1.25A | 3me6C-3t1wA:undetectable | 3me6C-3t1wA:21.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tk3 | CYTOCHROME P450 2B4 (Oryctolaguscuniculus) |
PF00067(p450) | 7 | VAL A 104PHE A 108ILE A 209ALA A 298THR A 302VAL A 367VAL A 477 | NoneNoneNoneCPZ A 501 (-3.5A)CPZ A 501 ( 3.7A)HEM A 500 ( 4.3A)None | 0.56A | 3me6C-3tk3A:62.9 | 3me6C-3tk3A:99.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tk3 | CYTOCHROME P450 2B4 (Oryctolaguscuniculus) |
PF00067(p450) | 6 | VAL A 104PHE A 108ILE A 209PHE A 297ALA A 298THR A 302 | NoneNoneNoneCPZ A 501 (-4.3A)CPZ A 501 (-3.5A)CPZ A 501 ( 3.7A) | 1.06A | 3me6C-3tk3A:62.9 | 3me6C-3tk3A:99.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3urg | ALR1010 PROTEIN (Nostoc sp. PCC7120) |
PF11535(Calci_bind_CcbP) | 5 | VAL A 65PHE A 42ILE A 100ALA A 112VAL A 105 | None NA A 127 (-4.5A)NoneNoneNone | 0.93A | 3me6C-3urgA:undetectable | 3me6C-3urgA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux8 | EXCINUCLEASE ABC, ASUBUNIT (Geobacillus sp.Y412MC52) |
PF00005(ABC_tran) | 5 | VAL A 710PHE A 711ILE A 799ALA A 792VAL A 703 | None | 1.06A | 3me6C-3ux8A:undetectable | 3me6C-3ux8A:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8d | CHOLESTEROL7-ALPHA-MONOOXYGENASE (Homo sapiens) |
PF00067(p450) | 5 | ILE A 187PHE A 449ALA A 450THR A 290VAL A 282 | NoneNoneHEM A 601 (-3.5A)HEM A 601 (-4.2A)None | 1.19A | 3me6C-3v8dA:26.5 | 3me6C-3v8dA:26.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vz0 | PUTATIVENAD-DEPENDENTALDEHYDEDEHYDROGENASE (Gluconobacteroxydans) |
PF00171(Aldedh) | 5 | VAL A 369PHE A 280ALA A 287THR A 289VAL A 330 | None | 1.18A | 3me6C-3vz0A:undetectable | 3me6C-3vz0A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vz0 | PUTATIVENAD-DEPENDENTALDEHYDEDEHYDROGENASE (Gluconobacteroxydans) |
PF00171(Aldedh) | 5 | VAL A 369PHE A 280ILE A 347ALA A 287THR A 289 | None | 1.21A | 3me6C-3vz0A:undetectable | 3me6C-3vz0A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zbi | TRAF PROTEIN (Escherichiacoli) |
PF03743(TrbI) | 5 | VAL A 889ILE A 820THR A 816VAL A 767VAL A 787 | None | 0.86A | 3me6C-3zbiA:undetectable | 3me6C-3zbiA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h1x | PHOSPHATE-BINDINGPROTEIN PSTS 2 (Streptococcuspneumoniae) |
PF12849(PBP_like_2) | 6 | VAL A 260PHE A 52ILE A 94ALA A 74VAL A 83VAL A 87 | None | 1.34A | 3me6C-4h1xA:undetectable | 3me6C-4h1xA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h27 | L-SERINEDEHYDRATASE/L-THREONINE DEAMINASE (Homo sapiens) |
PF00291(PALP) | 5 | VAL A 167PHE A 236ALA A 203THR A 206VAL A 245 | LLP A 41 ( 4.1A)NoneNoneNoneNone | 1.07A | 3me6C-4h27A:undetectable | 3me6C-4h27A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hse | CHAPERONE PROTEINCLPB (Thermusthermophilus) |
PF00004(AAA) | 5 | VAL A 182PHE A 268ILE A 303ALA A 206VAL A 329 | NoneNoneNoneADP A 602 (-3.6A)None | 0.97A | 3me6C-4hseA:undetectable | 3me6C-4hseA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i4n | INTRACELLULARPROTEASE/AMIDASE (Vibrio cholerae) |
no annotation | 5 | PHE A 94PHE A 183ILE A 150ALA A 275VAL A 283 | None | 1.19A | 3me6C-4i4nA:undetectable | 3me6C-4i4nA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4je1 | PROBABLE THIOLPEROXIDASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | VAL A 82ILE A 80PHE A 27ALA A 25VAL A 136 | None | 1.17A | 3me6C-4je1A:undetectable | 3me6C-4je1A:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgi | UNCHARACTERIZEDPROTEIN (Escherichiacoli) |
PF13678(Peptidase_M85) | 5 | VAL A 189ILE A 105PHE A 90THR A 79VAL A 161 | None | 1.08A | 3me6C-4lgiA:undetectable | 3me6C-4lgiA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lpq | ERFK/YBIS/YCFS/YNHGFAMILY PROTEIN (Xylanimonascellulosilytica) |
PF01471(PG_binding_1)PF03734(YkuD) | 5 | VAL A 207ILE A 209PHE A 279ALA A 284VAL A 303 | None | 1.21A | 3me6C-4lpqA:undetectable | 3me6C-4lpqA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nen | INTEGRIN ALPHA-X (Homo sapiens) |
PF00092(VWA)PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | VAL A 32PHE A 18PHE A 11ALA A 56THR A 54 | None | 1.05A | 3me6C-4nenA:undetectable | 3me6C-4nenA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o0m | CIRCADIAN CLOCKPROTEIN KINASE KAIC (Thermosynechococcuselongatus) |
PF06745(ATPase) | 5 | ILE A 131ALA A 169THR A 42VAL A 148VAL A 75 | None | 1.23A | 3me6C-4o0mA:undetectable | 3me6C-4o0mA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2i | NON-LEE ENCODED TYPEIII EFFECTOR C (Citrobacterrodentium) |
PF13678(Peptidase_M85) | 5 | VAL A 189ILE A 105PHE A 90THR A 79VAL A 161 | None | 1.18A | 3me6C-4o2iA:undetectable | 3me6C-4o2iA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qji | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE/PHOSPHOPANTOTHENATE--CYSTEINE LIGASE (Mycolicibacteriumsmegmatis) |
PF04127(DFP) | 5 | VAL A 221ILE A 401ALA A 406VAL A 272VAL A 330 | None | 1.19A | 3me6C-4qjiA:undetectable | 3me6C-4qjiA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qt8 | MACROPHAGE-STIMULATING PROTEIN RECEPTOR (Homo sapiens) |
no annotation | 5 | VAL B 520ILE B 471ALA B 462VAL B 502VAL B 498 | None | 1.21A | 3me6C-4qt8B:undetectable | 3me6C-4qt8B:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl1 | TYPE I POLYKETIDESYNTHASE AVES 1 (Streptomycesavermitilis) |
PF00698(Acyl_transf_1) | 5 | VAL A 142PHE A 96ALA A 59VAL A 72VAL A 68 | None | 1.26A | 3me6C-4rl1A:undetectable | 3me6C-4rl1A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8u | LINKER L1 (Glossoscolexpaulistus) |
PF16915(Eryth_link_C) | 5 | VAL M 115ILE M 208PHE M 153ALA M 152VAL M 192 | None | 1.11A | 3me6C-4u8uM:undetectable | 3me6C-4u8uM:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aca | VP3 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | VAL 3 205PHE 3 80ALA 3 79VAL 3 186VAL 3 161 | None | 1.02A | 3me6C-5aca3:undetectable | 3me6C-5aca3:18.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e0e | CYTOCHROME P450FAMILY 2 SUBFAMILY B (Neotoma lepida) |
PF00067(p450) | 5 | VAL A 104PHE A 108ILE A 209ALA A 298VAL A 367 | NoneNoneNoneHEM A 501 ( 3.1A)HEM A 501 ( 4.4A) | 1.02A | 3me6C-5e0eA:53.6 | 3me6C-5e0eA:79.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e0e | CYTOCHROME P450FAMILY 2 SUBFAMILY B (Neotoma lepida) |
PF00067(p450) | 5 | VAL A 104PHE A 108ILE A 209THR A 302VAL A 367 | NoneNoneNoneCPZ A 502 ( 4.0A)HEM A 501 ( 4.4A) | 0.80A | 3me6C-5e0eA:53.6 | 3me6C-5e0eA:79.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eaw | DNA REPLICATIONATP-DEPENDENTHELICASE/NUCLEASEDNA2 (Mus musculus) |
PF08696(Dna2)PF13086(AAA_11)PF13087(AAA_12) | 5 | VAL A 673ILE A 761ALA A 661THR A 658VAL A 784 | None | 1.24A | 3me6C-5eawA:undetectable | 3me6C-5eawA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eco | JASMONIC ACID-AMIDOSYNTHETASE JAR1 (Arabidopsisthaliana) |
PF03321(GH3) | 5 | VAL A 390ILE A 337PHE A 421THR A 351VAL A 354 | None | 1.21A | 3me6C-5ecoA:undetectable | 3me6C-5ecoA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fji | BETA-GLUCOSIDASE (Aspergillusfumigatus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | VAL A 504ILE A 535ALA A 568THR A 567VAL A 538 | None | 1.01A | 3me6C-5fjiA:undetectable | 3me6C-5fjiA:19.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2t | PERIODIC TRYPTOPHANPROTEIN 2 (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | VAL A 390PHE A 383ILE A 369ALA A 413VAL A 361 | None | 0.98A | 3me6C-5i2tA:undetectable | 3me6C-5i2tA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwx | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Bacillussubtilis) |
PF02542(YgbB) | 5 | VAL A 85ILE A 155ALA A 123VAL A 45VAL A 153 | None | 1.23A | 3me6C-5iwxA:undetectable | 3me6C-5iwxA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j78 | ACETALDEHYDEDEHYDROGENASE(ACETYLATING) (Parageobacillusthermoglucosidasius) |
PF00171(Aldedh) | 5 | VAL A 281PHE A 370ILE A 285ALA A 291VAL A 258 | None | 1.11A | 3me6C-5j78A:undetectable | 3me6C-5j78A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw3 | POLY(BETA-D-MANNURONATE) C5 EPIMERASE 6 (Azotobactervinelandii) |
no annotation | 5 | VAL A 262ILE A 285ALA A 280THR A 320VAL A 302 | None | 1.25A | 3me6C-5lw3A:undetectable | 3me6C-5lw3A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mr7 | GRAINYHEAD-LIKEPROTEIN 2 HOMOLOG (Homo sapiens) |
no annotation | 5 | VAL A 300ILE A 278PHE A 468THR A 268VAL A 371 | None | 1.25A | 3me6C-5mr7A:undetectable | 3me6C-5mr7A:10.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usc | PREPHENATEDEHYDROGENASE (Bacillusanthracis) |
PF02153(PDH) | 5 | ILE A 25ALA A 32THR A 178VAL A 78VAL A 107 | None | 1.24A | 3me6C-5uscA:undetectable | 3me6C-5uscA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5utt | SORTASE (Actinomycesoris) |
PF04203(Sortase) | 5 | VAL A 170PHE A 179ILE A 114PHE A 143ALA A 144 | None | 0.98A | 3me6C-5uttA:undetectable | 3me6C-5uttA:16.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wbg | CYTOCHROME P450 2B6 (Homo sapiens) |
no annotation | 9 | VAL A 104PHE A 108PHE A 206ILE A 209PHE A 297ALA A 298THR A 302VAL A 367VAL A 477 | None9ZJ A 502 (-4.4A)9ZJ A 502 (-2.6A)9ZJ A 502 ( 4.8A)9ZJ A 502 ( 4.5A)9ZJ A 502 ( 3.5A)9ZJ A 502 ( 3.9A)9ZJ A 502 ( 4.2A)None | 0.46A | 3me6C-5wbgA:59.1 | 3me6C-5wbgA:86.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wbg | CYTOCHROME P450 2B6 (Homo sapiens) |
no annotation | 7 | VAL A 104PHE A 115PHE A 206ILE A 209PHE A 297ALA A 298THR A 302 | None9ZJ A 502 (-4.7A)9ZJ A 502 (-2.6A)9ZJ A 502 ( 4.8A)9ZJ A 502 ( 4.5A)9ZJ A 502 ( 3.5A)9ZJ A 502 ( 3.9A) | 1.42A | 3me6C-5wbgA:59.1 | 3me6C-5wbgA:86.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wgc | DAUNORUBICIN-DOXORUBICIN POLYKETIDESYNTHASE (Streptomycespeucetius) |
no annotation | 5 | PHE A 277ILE A 282ALA A 275VAL A 325VAL A 262 | NoneNoneAFY A 401 (-3.6A)NoneNone | 0.92A | 3me6C-5wgcA:undetectable | 3me6C-5wgcA:11.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 5 | VAL A 884PHE A 940ILE A 952VAL A 874VAL A 865 | None | 1.24A | 3me6C-5wugA:undetectable | 3me6C-5wugA:8.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 5 | ILE A 135PHE A 68ALA A 54VAL A 140VAL A 138 | None | 1.17A | 3me6C-5yqwA:undetectable | 3me6C-5yqwA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homo sapiens) |
no annotation | 5 | VAL A 145PHE A 102PHE A 120ILE A 123VAL A 127 | None | 1.26A | 3me6C-6bx6A:undetectable | 3me6C-6bx6A:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cc4 | SOLUBLE CYTOCHROMEB562, LIPID IIFLIPPASE MURJCHIMERA (Escherichiacoli) |
no annotation | 5 | VAL A 229ILE A 67ALA A 149THR A 153VAL A 84 | None | 1.19A | 3me6C-6cc4A:undetectable | 3me6C-6cc4A:10.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dft | - (-) |
no annotation | 5 | ILE B 179PHE B 211ALA B 99THR B 97VAL B 106 | NoneNoneNAD B 500 (-3.2A)NoneNone | 1.17A | 3me6C-6dftB:undetectable | 3me6C-6dftB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6du8 | - (-) |
no annotation | 5 | VAL A 548PHE A 547PHE A 517ILE A 520PHE A 488 | None | 1.16A | 3me6C-6du8A:undetectable | 3me6C-6du8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC2 (Saccharomycescerevisiae) |
no annotation | 5 | VAL B 233PHE B 283ILE B 240ALA B 350VAL B 256 | None | 1.25A | 3me6C-6f42B:undetectable | 3me6C-6f42B:11.44 |