SIMILAR PATTERNS OF AMINO ACIDS FOR 3MDT_B_VORB506
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwu | ENOYL ACP REDUCTASE (Brassica napus) |
PF13561(adh_short_C2) | 5 | LEU A 186ILE A 231ALA A 266ALA A 37ALA A 273 | NAD A 501 (-3.6A)NoneNoneNoneNone | 1.12A | 3mdtB-1cwuA:0.0 | 3mdtB-1cwuA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 6 | LEU A 501SER A 500ILE A 445ALA A 423ALA A 509ALA A 442 | None | 1.33A | 3mdtB-1fbwA:0.0 | 3mdtB-1fbwA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fpq | ISOLIQUIRITIGENIN2'-O-METHYLTRANSFERASE (Medicago sativa) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 5 | LEU A 49PHE A 50ALA A 133THR A 137ALA A 43 | None | 1.11A | 3mdtB-1fpqA:undetectable | 3mdtB-1fpqA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ir6 | EXONUCLEASE RECJ (Thermusthermophilus) |
PF01368(DHH)PF02272(DHHA1) | 5 | LEU A 288ILE A 272ALA A 215THR A 218ALA A 83 | None | 1.00A | 3mdtB-1ir6A:0.0 | 3mdtB-1ir6A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4l | 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATESYNTHASE (Magnaporthegrisea) |
PF00926(DHBP_synthase) | 5 | LEU A 77PHE A 131ALA A 117ALA A 46ALA A 123 | None | 0.87A | 3mdtB-1k4lA:0.0 | 3mdtB-1k4lA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n3s | GTP CYCLOHYDROLASE I (Escherichiacoli) |
PF01227(GTP_cyclohydroI) | 5 | LEU A 162VAL A 141ALA A 121ALA A 124THR A 100 | None | 1.13A | 3mdtB-1n3sA:undetectable | 3mdtB-1n3sA:21.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1n97 | CYP175A1 (Thermusthermophilus) |
PF00067(p450) | 5 | TYR A 68ALA A 221THR A 225ALA A 268THR A 372 | HEM A 602 (-4.6A)HEM A 602 (-3.3A)HEM A 602 (-3.8A)HEM A 602 ( 4.0A)None | 0.93A | 3mdtB-1n97A:40.0 | 3mdtB-1n97A:31.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1n97 | CYP175A1 (Thermusthermophilus) |
PF00067(p450) | 5 | TYR A 68LEU A 71THR A 225ALA A 268THR A 372 | HEM A 602 (-4.6A)EDO A 715 ( 4.9A)HEM A 602 (-3.8A)HEM A 602 ( 4.0A)None | 1.08A | 3mdtB-1n97A:40.0 | 3mdtB-1n97A:31.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvp | TATA BOX BINDINGPROTEIN (Homo sapiens) |
PF00352(TBP) | 5 | VAL A 172ILE A 168ALA A 211ALA A 224THR A 209 | None | 1.12A | 3mdtB-1nvpA:undetectable | 3mdtB-1nvpA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o60 | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Haemophilusinfluenzae) |
PF00793(DAHP_synth_1) | 5 | TYR A 52VAL A 90ILE A 111ALA A 56THR A 94 | None | 1.08A | 3mdtB-1o60A:0.0 | 3mdtB-1o60A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpo | QUINOLINATE ACIDPHOSPHORIBOSYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | LEU A 114SER A 115ALA A 59THR A 62ALA A 11 | None | 1.02A | 3mdtB-1qpoA:undetectable | 3mdtB-1qpoA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7h | ORNITHINECYCLODEAMINASE (Pseudomonasputida) |
PF02423(OCD_Mu_crystall) | 5 | LEU A 152PHE A 148ALA A 114ALA A 27ALA A 120 | None | 1.04A | 3mdtB-1u7hA:undetectable | 3mdtB-1u7hA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uhp | HYPOTHETICAL PROTEINKIAA1095 (Homo sapiens) |
PF00595(PDZ) | 5 | LEU A 21ILE A 93ALA A 82ALA A 89THR A 88 | None | 0.95A | 3mdtB-1uhpA:undetectable | 3mdtB-1uhpA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzn | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 5 | LEU A 224PHE A 223SER A 226ILE A 237ALA A 235 | None | 1.06A | 3mdtB-1uznA:undetectable | 3mdtB-1uznA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vft | ALANINE RACEMASE (Streptomyceslavendulae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | VAL A 104ILE A 96ALA A 154ALA A 117THR A 159 | None | 1.07A | 3mdtB-1vftA:undetectable | 3mdtB-1vftA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wkm | METHIONINEAMINOPEPTIDASE (Pyrococcusfuriosus) |
PF00557(Peptidase_M24) | 5 | LEU A 54SER A 55ILE A 37ALA A 95ALA A 20 | NoneNoneNone MN A 297 ( 4.8A)None | 1.08A | 3mdtB-1wkmA:undetectable | 3mdtB-1wkmA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yd7 | 2-KETOACID:FERREDOXINOXIDOREDUCTASESUBUNIT ALPHA (Pyrococcusfuriosus) |
PF01855(POR_N) | 5 | PHE A 7ILE A 190ALA A 25THR A 159ALA A 155 | None | 1.12A | 3mdtB-1yd7A:undetectable | 3mdtB-1yd7A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ykg | SULFITE REDUCTASE[NADPH] FLAVOPROTEINALPHA-COMPONENT (Escherichiacoli) |
PF00258(Flavodoxin_1) | 5 | LEU A 134PHE A 133SER A 136ILE A 105ALA A 106 | None | 1.08A | 3mdtB-1ykgA:undetectable | 3mdtB-1ykgA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zgj | ISOFLAVANONE4'-O-METHYLTRANSFERASE' (Medicagotruncatula) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 5 | LEU A 104PHE A 84ILE A 45ALA A 36ALA A 44 | None | 0.88A | 3mdtB-1zgjA:undetectable | 3mdtB-1zgjA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a5z | HYPOTHETICAL PROTEINSO2946 (Shewanellaoneidensis) |
no annotation | 5 | PHE A 251VAL A 122ILE A 228ALA A 105THR A 141 | None | 1.12A | 3mdtB-2a5zA:undetectable | 3mdtB-2a5zA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bcc | UBIQUINOL CYTOCHROMEC OXIDOREDUCTASE (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 345VAL A 410ILE A 276ALA A 269ALA A 275 | None | 1.07A | 3mdtB-2bccA:undetectable | 3mdtB-2bccA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cuy | MALONYL COA-[ACYLCARRIER PROTEIN]TRANSACYLASE (Thermusthermophilus) |
PF00698(Acyl_transf_1) | 5 | LEU A 144VAL A 170ILE A 140ALA A 130ALA A 153 | None | 1.13A | 3mdtB-2cuyA:undetectable | 3mdtB-2cuyA:25.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dnq | RNA-BINDING PROTEIN4B (Homo sapiens) |
PF00076(RRM_1) | 5 | LEU A 4SER A 70ILE A 42ALA A 47THR A 46 | None | 1.12A | 3mdtB-2dnqA:undetectable | 3mdtB-2dnqA:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7c | TOXIN A (Clostridioidesdifficile) |
PF01473(CW_binding_1) | 5 | VAL A 167ILE A 205ALA A 214THR A 216ALA A 235 | NoneGOL A 501 (-3.9A)NoneNoneNone | 1.08A | 3mdtB-2g7cA:undetectable | 3mdtB-2g7cA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqd | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Staphylococcusaureus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU A 55PHE A 58THR A 76ALA A 236THR A 192 | None | 1.08A | 3mdtB-2gqdA:undetectable | 3mdtB-2gqdA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ill | TITIN (Homo sapiens) |
PF07679(I-set) | 5 | LEU A 160VAL A 120SER A 121ILE A 143ALA A 171 | None | 1.07A | 3mdtB-2illA:undetectable | 3mdtB-2illA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nxg | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Aquifexaeolicus) |
PF00793(DAHP_synth_1) | 5 | ILE A1208ALA A1008ALA A1237ALA A1183THR A1184 | None | 1.05A | 3mdtB-2nxgA:undetectable | 3mdtB-2nxgA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3b | SUGAR-NON-SPECIFICNUCLEASE INHIBITOR (Nostoc sp. PCC7120) |
PF07924(NuiA) | 5 | LEU B 19PHE B 29SER B 16ALA B 70THR B 71 | None | 0.88A | 3mdtB-2o3bB:undetectable | 3mdtB-2o3bB:17.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q9g | CYTOCHROME P450 46A1 (Homo sapiens) |
PF00067(p450) | 10 | TYR A 109LEU A 112PHE A 121VAL A 126ILE A 222ALA A 302THR A 306ALA A 367ALA A 474THR A 475 | NoneNoneNoneHEM A 505 ( 3.8A)NoneHEM A 505 (-3.7A)HEM A 505 (-3.7A)HEM A 505 (-3.5A)NoneNone | 0.47A | 3mdtB-2q9gA:65.5 | 3mdtB-2q9gA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q9g | CYTOCHROME P450 46A1 (Homo sapiens) |
PF00067(p450) | 10 | TYR A 109PHE A 121VAL A 126SER A 127ILE A 222ALA A 302THR A 306ALA A 367ALA A 474THR A 475 | NoneNoneHEM A 505 ( 3.8A)NoneNoneHEM A 505 (-3.7A)HEM A 505 (-3.7A)HEM A 505 (-3.5A)NoneNone | 0.42A | 3mdtB-2q9gA:65.5 | 3mdtB-2q9gA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yne | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Plasmodiumvivax) |
PF01233(NMT)PF02799(NMT_C) | 5 | LEU A 379PHE A 381ILE A 353ALA A 366ALA A 352 | None | 1.13A | 3mdtB-2yneA:undetectable | 3mdtB-2yneA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1a | 5'-NUCLEOTIDASE (Thermusthermophilus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | TYR A 513LEU A 514ILE A 391ALA A 522ALA A 337 | None | 0.99A | 3mdtB-2z1aA:undetectable | 3mdtB-2z1aA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z6h | CATENIN BETA-1 (Homo sapiens) |
PF00514(Arm) | 5 | LEU A 221SER A 179ILE A 231THR A 201ALA A 197 | None | 1.13A | 3mdtB-2z6hA:undetectable | 3mdtB-2z6hA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zal | L-ASPARAGINASE (Escherichiacoli) |
PF01112(Asparaginase_2) | 5 | LEU A 60ILE A 8ALA A 34ALA B 298THR B 308 | None | 1.05A | 3mdtB-2zalA:undetectable | 3mdtB-2zalA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxo | SINGLE-STRANDED DNASPECIFIC EXONUCLEASERECJ (Thermusthermophilus) |
PF01368(DHH)PF02272(DHHA1) | 5 | LEU A 288ILE A 272ALA A 215THR A 218ALA A 83 | None | 1.05A | 3mdtB-2zxoA:undetectable | 3mdtB-2zxoA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c17 | L-ASPARAGINASEPRECURSOR (Escherichiacoli) |
PF01112(Asparaginase_2) | 5 | LEU A 60ILE A 8ALA A 34ALA A 298THR A 308 | None | 1.10A | 3mdtB-3c17A:undetectable | 3mdtB-3c17A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cb7 | LYS-RICH LYSOZYME 2 (Musca domestica) |
PF00062(Lys) | 5 | LEU A 12PHE A 7SER A 11ILE A 57ALA A 93 | LEU A 12 ( 0.6A)PHE A 7 ( 1.3A)SER A 11 ( 0.0A)ILE A 57 ( 0.6A)ALA A 93 ( 0.0A) | 0.99A | 3mdtB-3cb7A:undetectable | 3mdtB-3cb7A:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dd6 | RIBONUCLEASE PH (Bacillusanthracis) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 5 | LEU A 93ILE A 191ALA A 133ALA A 128ALA A 161 | None | 1.12A | 3mdtB-3dd6A:undetectable | 3mdtB-3dd6A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e60 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN ]SYNTHASE II (Bartonellahenselae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | VAL A 12ILE A 111ALA A 85ALA A 78ALA A 149 | None | 1.02A | 3mdtB-3e60A:undetectable | 3mdtB-3e60A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eez | PUTATIVE MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Ruegeriapomeroyi) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | VAL A 194ILE A 174ALA A 203ALA A 236ALA A 209 | None | 1.03A | 3mdtB-3eezA:undetectable | 3mdtB-3eezA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f1x | SERINEACETYLTRANSFERASE (Bacteroidesvulgatus) |
PF00132(Hexapep) | 5 | PHE A 203ILE A 213ALA A 156THR A 189ALA A 185 | None | 0.99A | 3mdtB-3f1xA:undetectable | 3mdtB-3f1xA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | LEU B 123SER B 125ILE B 153ALA B 94ALA B 85 | None | 1.09A | 3mdtB-3hkzB:undetectable | 3mdtB-3hkzB:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | ILE A 212ALA A 234THR A 593ALA A 589ALA A 110 | None | 1.09A | 3mdtB-3i04A:undetectable | 3mdtB-3i04A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6r | DIHYDROOROTATEDEHYDROGENASEHOMOLOG,MITOCHONDRIAL (Plasmodiumfalciparum) |
PF01180(DHO_dh) | 6 | LEU A 430PHE A 488SER A 457ILE A 442ALA A 443THR A 496 | None | 1.37A | 3mdtB-3i6rA:undetectable | 3mdtB-3i6rA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lov | PROTOPORPHYRINOGENOXIDASE (Exiguobacteriumsibiricum) |
PF01593(Amino_oxidase) | 5 | LEU A 169ILE A 100ALA A 341THR A 343ALA A 89 | None | 1.08A | 3mdtB-3lovA:undetectable | 3mdtB-3lovA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lu2 | LMO2462 PROTEIN (Listeriamonocytogenes) |
PF01244(Peptidase_M19) | 5 | VAL A 170SER A 171ILE A 247ALA A 218ALA A 212 | None | 1.03A | 3mdtB-3lu2A:undetectable | 3mdtB-3lu2A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT BETA (Saccharomycescerevisiae) |
PF00365(PFK) | 5 | TYR B 767LEU B 768SER B 718ALA B 598ALA B 736 | NoneNoneFDP B 2 (-2.5A)NoneNone | 1.10A | 3mdtB-3o8oB:undetectable | 3mdtB-3o8oB:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0w | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Ralstoniapickettii) |
PF13378(MR_MLE_C) | 6 | VAL A 341ILE A 325ALA A 328ALA A 308ALA A 303THR A 304 | None | 1.22A | 3mdtB-3p0wA:undetectable | 3mdtB-3p0wA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfr | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Actinobacillussuccinogenes) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 6 | VAL A 326ILE A 310ALA A 313ALA A 293ALA A 288THR A 289 | None | 1.25A | 3mdtB-3pfrA:undetectable | 3mdtB-3pfrA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pi7 | NADH OXIDOREDUCTASE (Mesorhizobiumloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 146ALA A 58ALA A 123ALA A 110THR A 111 | NoneNoneNoneNoneGOL A 349 (-3.8A) | 1.13A | 3mdtB-3pi7A:undetectable | 3mdtB-3pi7A:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r5e | TRANSALDOLASE (Corynebacteriumglutamicum) |
PF00923(TAL_FSA) | 5 | LEU A 329PHE A 333ILE A 210ALA A 315ALA A 229 | None | 1.05A | 3mdtB-3r5eA:undetectable | 3mdtB-3r5eA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rhd | LACTALDEHYDEDEHYDROGENASE (Methanocaldococcusjannaschii) |
PF00171(Aldedh) | 5 | LEU A 62ILE A 155ALA A 148ALA A 450ALA A 154 | None | 1.13A | 3mdtB-3rhdA:undetectable | 3mdtB-3rhdA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rhd | LACTALDEHYDEDEHYDROGENASE (Methanocaldococcusjannaschii) |
PF00171(Aldedh) | 5 | LEU A 62PHE A 102ILE A 155ALA A 450ALA A 154 | None | 1.00A | 3mdtB-3rhdA:undetectable | 3mdtB-3rhdA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tts | BETA-GALACTOSIDASE (Bacilluscirculans) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | TYR A 403VAL A 424THR A 282ALA A 288THR A 287 | None | 1.13A | 3mdtB-3ttsA:undetectable | 3mdtB-3ttsA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tx1 | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Listeriamonocytogenes) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 5 | LEU A 145PHE A 186ILE A 141ALA A 95ALA A 129 | NoneNoneNoneNoneFAD A 299 (-4.0A) | 1.10A | 3mdtB-3tx1A:undetectable | 3mdtB-3tx1A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uav | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Bacillus cereus) |
PF01048(PNP_UDP_1) | 6 | ILE A 69ALA A 156THR A 111ALA A 109ALA A 184THR A 183 | None | 1.22A | 3mdtB-3uavA:undetectable | 3mdtB-3uavA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vnd | TRYPTOPHAN SYNTHASEALPHA CHAIN (Shewanellafrigidimarina) |
PF00290(Trp_syntA) | 5 | LEU A 100PHE A 53VAL A 107ILE A 86ALA A 122 | None | 1.13A | 3mdtB-3vndA:undetectable | 3mdtB-3vndA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsj | 2-AMINO-5-CHLOROPHENOL 1,6-DIOXYGENASEBETA SUBUNIT (Comamonastestosteroni) |
PF02900(LigB) | 5 | LEU B 187VAL B 147ILE B 5THR B 181ALA B 177 | None | 1.04A | 3mdtB-3vsjB:undetectable | 3mdtB-3vsjB:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ah6 | ASPARTATE--TRNALIGASE,MITOCHONDRIAL (Homo sapiens) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 5 | LEU A 81VAL A 143ILE A 72ALA A 146ALA A 110 | None | 1.08A | 3mdtB-4ah6A:undetectable | 3mdtB-4ah6A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bqn | CAPSULARPOLYSACCHARIDEBIOSYNTHESIS PROTEIN (Burkholderiapseudomallei) |
no annotation | 5 | TYR A 8LEU A 62VAL A 10ALA A 211ALA A 217 | None | 0.86A | 3mdtB-4bqnA:undetectable | 3mdtB-4bqnA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dgu | PUTATIVE CELLADHESION PROTEIN (Bacteroidesthetaiotaomicron) |
no annotation | 5 | LEU A 143VAL A 141SER A 142ILE A 66ALA A 70 | None | 1.14A | 3mdtB-4dguA:undetectable | 3mdtB-4dguA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4du6 | GTP CYCLOHYDROLASE 1 (Yersinia pestis) |
PF01227(GTP_cyclohydroI) | 5 | LEU A 161VAL A 140ALA A 120ALA A 123THR A 99 | None | 1.10A | 3mdtB-4du6A:undetectable | 3mdtB-4du6A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecd | CHORISMATE SYNTHASE (Bifidobacteriumlongum) |
PF01264(Chorismate_synt) | 5 | LEU A 248ILE A 309ALA A 364ALA A 227THR A 162 | None | 1.00A | 3mdtB-4ecdA:undetectable | 3mdtB-4ecdA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fc7 | PEROXISOMAL2,4-DIENOYL-COAREDUCTASE (Homo sapiens) |
PF13561(adh_short_C2) | 5 | VAL A 144SER A 145ILE A 109ALA A 100ALA A 31 | None | 1.09A | 3mdtB-4fc7A:undetectable | 3mdtB-4fc7A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g34 | EUKARYOTICTRANSLATIONINITIATION FACTOR2-ALPHA KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 927PHE A 926SER A 929ILE A 650ALA A 641 | None | 1.14A | 3mdtB-4g34A:undetectable | 3mdtB-4g34A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyr | GLUCARATEDEHYDRATASE (Acidaminococcusintestini) |
PF13378(MR_MLE_C) | 6 | VAL A 321ILE A 305ALA A 308ALA A 288ALA A 283THR A 284 | None | 1.29A | 3mdtB-4hyrA:undetectable | 3mdtB-4hyrA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3u | ALDEHYDEDEHYDROGENASE (NAD+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | LEU A 73PHE A 113ILE A 172ALA A 470ALA A 171 | None | 1.01A | 3mdtB-4i3uA:undetectable | 3mdtB-4i3uA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iiv | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Escherichiacoli) |
PF13561(adh_short_C2) | 5 | LEU A 138ILE A 181ALA A 213ALA A 19ALA A 220 | NAP A1901 ( 4.4A)NoneNoneNoneNone | 1.09A | 3mdtB-4iivA:undetectable | 3mdtB-4iivA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6c | CYTOCHROME P450MONOOXYGENASE (Nocardiafarcinica) |
PF00067(p450) | 5 | LEU A 153PHE A 149ILE A 253ALA A 373ALA A 367 | None | 1.12A | 3mdtB-4j6cA:32.3 | 3mdtB-4j6cA:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4knw | N-ACYLNEURAMINATE-9-PHOSPHATASE (Homo sapiens) |
PF13419(HAD_2) | 5 | TYR A 41LEU A 37ILE A 50THR A 75ALA A 81 | None | 1.13A | 3mdtB-4knwA:undetectable | 3mdtB-4knwA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqk | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF02277(DBI_PRT) | 5 | LEU A 251VAL A 155SER A 156ILE A 277ALA A 273 | None | 0.92A | 3mdtB-4kqkA:undetectable | 3mdtB-4kqkA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbx | TCDA (Clostridioidesdifficile) |
PF01473(CW_binding_1) | 5 | VAL A 49ILE A 87ALA A 96THR A 98ALA A 117 | None | 1.07A | 3mdtB-4nbxA:undetectable | 3mdtB-4nbxA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9n | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Chlamydiatrachomatis) |
PF13561(adh_short_C2) | 5 | LEU A 176ILE A 221ALA A 256ALA A 27ALA A 263 | NAI A 301 (-3.8A)NoneNoneNoneNone | 1.14A | 3mdtB-4q9nA:undetectable | 3mdtB-4q9nA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qts | CRISPR TYPEIII-ASSOCIATED RAMPPROTEIN CSM4 (Methanocaldococcusjannaschii) |
PF03787(RAMPs) | 5 | LEU A 62PHE A 206SER A 63ILE A 37ALA A 36 | None | 1.12A | 3mdtB-4qtsA:undetectable | 3mdtB-4qtsA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7l | LEUCINE-RICH REPEATSANDIMMUNOGLOBULIN-LIKEDOMAINS PROTEIN 1 (Homo sapiens) |
PF01463(LRRCT)PF13855(LRR_8) | 5 | LEU A 408ILE A 439ALA A 429ALA A 377ALA A 426 | None | 1.03A | 3mdtB-4u7lA:undetectable | 3mdtB-4u7lA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ut1 | FLAGELLARHOOK-ASSOCIATEDPROTEIN (Burkholderiapseudomallei) |
PF06429(Flg_bbr_C) | 5 | LEU A 367SER A 415ILE A 399ALA A 388THR A 389 | None | 1.06A | 3mdtB-4ut1A:undetectable | 3mdtB-4ut1A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wsb | POLYMERASE PB2 (Influenza Avirus) |
PF00604(Flu_PB2) | 5 | LEU C 280SER C 279ILE C 310ALA C 262ALA C 307 | None | 1.13A | 3mdtB-4wsbC:undetectable | 3mdtB-4wsbC:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzs | ECU04_1440 PROTEIN (Encephalitozooncuniculi) |
PF00352(TBP) | 5 | PHE D 113VAL D 32ALA D 71ALA D 84THR D 69 | None | 1.13A | 3mdtB-4wzsD:undetectable | 3mdtB-4wzsD:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x68 | BETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00144(Beta-lactamase) | 5 | LEU A 387SER A 385ILE A 58ALA A 41ALA A 36 | None | 1.05A | 3mdtB-4x68A:undetectable | 3mdtB-4x68A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmv | AMINOPEPTIDASE N (Escherichiacoli) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | LEU A 189ILE A 145ALA A 115ALA A 31ALA A 147 | None | 1.09A | 3mdtB-4xmvA:undetectable | 3mdtB-4xmvA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0z | CHOLINETRIMETHYLAMINE LYASE (Klebsiellapneumoniae) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | LEU A 599ILE A 403ALA A 645ALA A 703ALA A 651 | None | 1.06A | 3mdtB-5a0zA:undetectable | 3mdtB-5a0zA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c5g | SPHERULIN-4 (Aspergillusclavatus) |
PF12138(Spherulin4) | 5 | LEU A 236ILE A 206ALA A 250ALA A 223ALA A 205 | None | 1.13A | 3mdtB-5c5gA:undetectable | 3mdtB-5c5gA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 5 | LEU A 75ALA A 264THR A 268ALA A 328THR A 438 | NoneHEM A 501 (-3.6A)HEM A 501 (-3.4A)HEM A 501 ( 3.8A)None | 1.02A | 3mdtB-5e78A:43.2 | 3mdtB-5e78A:25.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f56 | SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE (Deinococcusradiodurans) |
PF01368(DHH)PF02272(DHHA1) | 5 | LEU A 291ILE A 275THR A 220ALA A 190ALA A 82 | None | 1.01A | 3mdtB-5f56A:undetectable | 3mdtB-5f56A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fz5 | TATA-BOX-BINDINGPROTEIN (Saccharomycescerevisiae) |
PF00352(TBP) | 5 | PHE O 155VAL O 74ILE O 70ALA O 126THR O 111 | None | 1.13A | 3mdtB-5fz5O:undetectable | 3mdtB-5fz5O:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5htp | PROBABLE SUGARKINASE (Synechococcuselongatus) |
PF02782(FGGY_C) | 5 | ILE A 223ALA A 142ALA A 67ALA A 224THR A 407 | None | 1.11A | 3mdtB-5htpA:undetectable | 3mdtB-5htpA:25.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jpn | COMPLEMENT C4-A (Homo sapiens) |
PF01835(A2M_N)PF07703(A2M_N_2) | 5 | LEU A 386VAL A 431SER A 432ALA A 450ALA A 458 | None | 1.13A | 3mdtB-5jpnA:undetectable | 3mdtB-5jpnA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kbm | CELL SURFACE CU-ONLYSUPEROXIDE DISMUTASE5 (Candidaalbicans) |
PF00080(Sod_Cu) | 5 | PHE A 48VAL A 60SER A 59ILE A 135ALA A 115 | None | 1.07A | 3mdtB-5kbmA:undetectable | 3mdtB-5kbmA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l7n | PLEXIN-A1 (Mus musculus) |
PF01833(TIG) | 5 | PHE A 954VAL A 957ILE A 922ALA A 986ALA A1031 | None | 1.07A | 3mdtB-5l7nA:undetectable | 3mdtB-5l7nA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lug | SPINDLIN-LIKEPROTEIN 2, ISOFORMCRA_A (Homo sapiens) |
PF02513(Spin-Ssty) | 5 | TYR A 181LEU A 178PHE A 162ILE A 119ALA A 122 | None | 0.97A | 3mdtB-5lugA:undetectable | 3mdtB-5lugA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz8 | ALDEHYDEDEHYDROGENASE 21 (Physcomitrellapatens) |
PF00171(Aldedh) | 5 | LEU A 86ILE A 185ALA A 178ALA A 479ALA A 184 | None | 1.08A | 3mdtB-5mz8A:undetectable | 3mdtB-5mz8A:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz8 | ALDEHYDEDEHYDROGENASE 21 (Physcomitrellapatens) |
PF00171(Aldedh) | 5 | LEU A 86PHE A 126ILE A 185ALA A 479ALA A 184 | None | 0.96A | 3mdtB-5mz8A:undetectable | 3mdtB-5mz8A:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oa3 | EUKARYOTICTRANSLATIONINITIATION FACTOR 2D (Homo sapiens) |
no annotation | 5 | TYR 0 64LEU 0 72ALA 0 24ALA 0 29THR 0 28 | None | 1.05A | 3mdtB-5oa30:undetectable | 3mdtB-5oa30:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5unq | PUTATIVE TAUTOMERASE (Pusillimonassp. T7-7) |
no annotation | 5 | LEU A 102VAL A 3ILE A 80THR A 86ALA A 26 | None | 1.08A | 3mdtB-5unqA:undetectable | 3mdtB-5unqA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xoe | ATP-DEPENDENT6-PHOSPHOFRUCTOKINASE (Staphylococcusaureus) |
no annotation | 5 | VAL A 98ILE A 32ALA A 273ALA A 22THR A 26 | None | 1.03A | 3mdtB-5xoeA:undetectable | 3mdtB-5xoeA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xse | KHG/KDPG ALDOLASE (Zymomonasmobilis) |
no annotation | 5 | VAL A 42ILE A 192ALA A 25ALA A 62ALA A 31 | None | 1.06A | 3mdtB-5xseA:undetectable | 3mdtB-5xseA:11.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zc3 | - (-) |
no annotation | 5 | LEU B 419ILE B 407ALA B 436ALA B 442THR B 441 | None | 1.01A | 3mdtB-5zc3B:undetectable | 3mdtB-5zc3B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bng | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Acinetobacterbaumannii) |
no annotation | 5 | TYR A 56VAL A 94ILE A 115ALA A 60THR A 98 | None | 1.12A | 3mdtB-6bngA:undetectable | 3mdtB-6bngA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fv5 | QUEUINETRNA-RIBOSYLTRANSFERASE ACCESSORYSUBUNIT 2 (Mus musculus) |
no annotation | 5 | LEU A 219PHE A 222ILE A 193ALA A 241ALA A 206 | None | 1.08A | 3mdtB-6fv5A:undetectable | 3mdtB-6fv5A:10.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN5 (Mus musculus) |
no annotation | 5 | VAL L 92SER L 91ILE L 472ALA L 464THR L 387 | None | 1.13A | 3mdtB-6g2jL:undetectable | 3mdtB-6g2jL:11.14 |