SIMILAR PATTERNS OF AMINO ACIDS FOR 3M0W_H_P77H203

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gve AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 3

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		5 LEU A  54
SER A  27
PHE A  31
ILE A  39
ASP A  20
 None
 1.44A 3m0wE-1gveA:
undetectable
3m0wF-1gveA:
undetectable
3m0wG-1gveA:
undetectable
3m0wH-1gveA:
undetectable		 3m0wE-1gveA:
16.94
3m0wF-1gveA:
16.94
3m0wG-1gveA:
16.94
3m0wH-1gveA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lua METHYLENE
TETRAHYDROMETHANOPTE
RIN DEHYDROGENASE

(Methylobacterium
extorquens) 		PF09176
(Mpt_N) 		5 LEU A 259
ILE A 280
CYH A 263
PHE A  64
SER A  16
 None
 1.26A 3m0wE-1luaA:
undetectable
3m0wF-1luaA:
undetectable
3m0wG-1luaA:
undetectable
3m0wH-1luaA:
undetectable		 3m0wE-1luaA:
15.25
3m0wF-1luaA:
15.25
3m0wG-1luaA:
15.25
3m0wH-1luaA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yve ACETOHYDROXY ACID
ISOMEROREDUCTASE

(Spinacia
oleracea) 		PF01450
(IlvC)
PF07991
(IlvN) 		5 ASP I 282
PHE I  86
PHE I 277
ASP I 289
SER I  90
 None
 1.40A 3m0wE-1yveI:
undetectable
3m0wF-1yveI:
undetectable
3m0wG-1yveI:
0.3
3m0wH-1yveI:
undetectable		 3m0wE-1yveI:
14.46
3m0wF-1yveI:
14.46
3m0wG-1yveI:
14.46
3m0wH-1yveI:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4k PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE-ASSOCIATE
D PROTEIN 1

(Homo sapiens) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		5 LEU A 151
SER A 154
PHE A 156
ILE A 331
SER A 186
 None
 1.15A 3m0wE-2c4kA:
undetectable
3m0wF-2c4kA:
undetectable
3m0wG-2c4kA:
undetectable
3m0wH-2c4kA:
undetectable		 3m0wE-2c4kA:
14.01
3m0wF-2c4kA:
14.01
3m0wG-2c4kA:
14.01
3m0wH-2c4kA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		5 LEU A 368
SER A 329
ILE A 343
PHE A 427
SER A 379
 None
 1.25A 3m0wE-2hi4A:
0.0
3m0wF-2hi4A:
undetectable
3m0wG-2hi4A:
undetectable
3m0wH-2hi4A:
undetectable		 3m0wE-2hi4A:
11.45
3m0wF-2hi4A:
11.45
3m0wG-2hi4A:
11.45
3m0wH-2hi4A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		5 LEU A 368
SER A 329
ILE A 343
PHE A 432
PHE A 427
 None
 1.46A 3m0wE-2hi4A:
0.0
3m0wF-2hi4A:
undetectable
3m0wG-2hi4A:
undetectable
3m0wH-2hi4A:
undetectable		 3m0wE-2hi4A:
11.45
3m0wF-2hi4A:
11.45
3m0wG-2hi4A:
11.45
3m0wH-2hi4A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ji4 PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE-ASSOCIATE
D PROTEIN 2

(Homo sapiens) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		5 LEU A 163
SER A 166
PHE A 168
ILE A 344
SER A 198
 None
CL  A1369 (-3.8A)
None
None
None
 1.18A 3m0wE-2ji4A:
undetectable
3m0wF-2ji4A:
undetectable
3m0wG-2ji4A:
undetectable
3m0wH-2ji4A:
undetectable		 3m0wE-2ji4A:
15.34
3m0wF-2ji4A:
15.34
3m0wG-2ji4A:
15.34
3m0wH-2ji4A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oxc PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX20

(Homo sapiens) 		PF00270
(DEAD) 		5 LEU A 121
ASP A 122
PHE A  82
ILE A 153
PHE A  64
 None
None
ADP  A 300 (-4.4A)
None
None
 1.31A 3m0wE-2oxcA:
undetectable
3m0wF-2oxcA:
undetectable
3m0wG-2oxcA:
undetectable
3m0wH-2oxcA:
undetectable		 3m0wE-2oxcA:
20.69
3m0wF-2oxcA:
20.69
3m0wG-2oxcA:
20.69
3m0wH-2oxcA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkd ZINC FINGER PROTEIN
ZPR1

(Mus musculus) 		PF03367
(zf-ZPR1) 		5 LEU A 143
SER A 203
PHE A 204
ASP A 121
SER A 122
 None
 1.39A 3m0wE-2qkdA:
undetectable
3m0wF-2qkdA:
undetectable
3m0wG-2qkdA:
undetectable
3m0wH-2qkdA:
undetectable		 3m0wE-2qkdA:
12.88
3m0wF-2qkdA:
12.88
3m0wG-2qkdA:
12.88
3m0wH-2qkdA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10

(Mus musculus) 		PF00085
(Thioredoxin)
PF00226
(DnaJ) 		5 LEU A 148
PHE A 228
ILE A 206
PHE A 171
ASP A 176
 None
 1.45A 3m0wE-3apqA:
undetectable
3m0wF-3apqA:
undetectable
3m0wG-3apqA:
undetectable
3m0wH-3apqA:
undetectable		 3m0wE-3apqA:
19.76
3m0wF-3apqA:
19.76
3m0wG-3apqA:
19.76
3m0wH-3apqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cc8 PUTATIVE
METHYLTRANSFERASE

(Bacillus cereus) 		PF13489
(Methyltransf_23) 		5 LEU A 154
ASP A 155
PHE A 218
ASP A 100
SER A 128
 None
NI  A 231 (-4.2A)
None
None
None
 1.43A 3m0wE-3cc8A:
undetectable
3m0wF-3cc8A:
undetectable
3m0wG-3cc8A:
undetectable
3m0wH-3cc8A:
undetectable		 3m0wE-3cc8A:
19.02
3m0wF-3cc8A:
19.02
3m0wG-3cc8A:
19.02
3m0wH-3cc8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eaf ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Aeropyrum
pernix) 		PF13458
(Peripla_BP_6) 		5 SER A 171
PHE A 410
ILE A 395
PHE A 298
ASP A 164
 None
 1.13A 3m0wE-3eafA:
undetectable
3m0wF-3eafA:
undetectable
3m0wG-3eafA:
undetectable
3m0wH-3eafA:
undetectable		 3m0wE-3eafA:
12.08
3m0wF-3eafA:
12.08
3m0wG-3eafA:
12.08
3m0wH-3eafA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eix HTSA PROTEIN

(Staphylococcus
aureus) 		PF01497
(Peripla_BP_2) 		5 ASP A 149
SER A 156
PHE A 157
ASP A 147
SER A 124
 None
 1.27A 3m0wE-3eixA:
undetectable
3m0wF-3eixA:
undetectable
3m0wG-3eixA:
undetectable
3m0wH-3eixA:
0.5		 3m0wE-3eixA:
17.29
3m0wF-3eixA:
17.29
3m0wG-3eixA:
17.29
3m0wH-3eixA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdb PUTATIVE
PLP-DEPENDENT
BETA-CYSTATHIONASE

(Corynebacterium
diphtheriae) 		PF00155
(Aminotran_1_2) 		5 LEU A 186
ASP A 188
PHE A 100
ILE A 215
ASP A  88
 None
LLP  A 222 ( 2.7A)
None
None
CL  A 381 ( 3.0A)
 1.42A 3m0wE-3fdbA:
undetectable
3m0wF-3fdbA:
0.0
3m0wG-3fdbA:
undetectable
3m0wH-3fdbA:
undetectable		 3m0wE-3fdbA:
14.55
3m0wF-3fdbA:
14.55
3m0wG-3fdbA:
14.55
3m0wH-3fdbA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcu DIPICOLINATE
SYNTHASE, B CHAIN

(Bacillus cereus) 		PF02441
(Flavoprotein) 		5 LEU A  79
SER A 108
ILE A  70
PHE A  10
SER A  97
 None
 1.50A 3m0wE-3mcuA:
undetectable
3m0wF-3mcuA:
undetectable
3m0wG-3mcuA:
undetectable
3m0wH-3mcuA:
undetectable		 3m0wE-3mcuA:
22.68
3m0wF-3mcuA:
22.68
3m0wG-3mcuA:
22.68
3m0wH-3mcuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no2 UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		no annotation 5 LEU A  26
SER A  59
PHE A  70
ILE A  35
SER A 187
 None
 1.45A 3m0wE-3no2A:
undetectable
3m0wF-3no2A:
undetectable
3m0wG-3no2A:
undetectable
3m0wH-3no2A:
undetectable		 3m0wE-3no2A:
16.86
3m0wF-3no2A:
16.86
3m0wG-3no2A:
16.86
3m0wH-3no2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		5 LEU A  42
ASP A  41
ILE A  95
PHE A  63
SER A  37
 None
 1.49A 3m0wE-3ojbA:
undetectable
3m0wF-3ojbA:
undetectable
3m0wG-3ojbA:
undetectable
3m0wH-3ojbA:
undetectable		 3m0wE-3ojbA:
19.86
3m0wF-3ojbA:
19.86
3m0wG-3ojbA:
19.86
3m0wH-3ojbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3plr UDP-GLUCOSE
6-DEHYDROGENASE

(Klebsiella
pneumoniae) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		5 LEU A 384
ASP A 383
PHE A 211
ILE A 229
SER A 317
 None
 1.41A 3m0wE-3plrA:
undetectable
3m0wF-3plrA:
undetectable
3m0wG-3plrA:
undetectable
3m0wH-3plrA:
undetectable		 3m0wE-3plrA:
15.32
3m0wF-3plrA:
15.32
3m0wG-3plrA:
15.32
3m0wH-3plrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r11 ENZYME OF ENOLASE
SUPERFAMILY

(Francisella
philomiragia) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 LEU A 107
ASP A 111
SER A 310
PHE A 311
ILE A 276
 None
 1.07A 3m0wE-3r11A:
undetectable
3m0wF-3r11A:
undetectable
3m0wG-3r11A:
undetectable
3m0wH-3r11A:
undetectable		 3m0wE-3r11A:
12.14
3m0wF-3r11A:
12.14
3m0wG-3r11A:
12.14
3m0wH-3r11A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sy8 ROCR

(Pseudomonas
aeruginosa) 		PF00072
(Response_reg)
PF00563
(EAL) 		5 LEU A 366
PHE A 321
ILE A 335
CYH A 368
SER A 356
 None
 1.35A 3m0wE-3sy8A:
undetectable
3m0wF-3sy8A:
undetectable
3m0wG-3sy8A:
undetectable
3m0wH-3sy8A:
undetectable		 3m0wE-3sy8A:
15.66
3m0wF-3sy8A:
15.66
3m0wG-3sy8A:
15.66
3m0wH-3sy8A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upy OXIDOREDUCTASE

(Brucella
abortus) 		PF03447
(NAD_binding_3) 		5 SER A 188
ILE A 236
CYH A 172
PHE A 291
SER A 260
 None
 1.45A 3m0wE-3upyA:
undetectable
3m0wF-3upyA:
undetectable
3m0wG-3upyA:
undetectable
3m0wH-3upyA:
undetectable		 3m0wE-3upyA:
12.75
3m0wF-3upyA:
12.75
3m0wG-3upyA:
12.75
3m0wH-3upyA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aie GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Lactobacillus
acidophilus) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		5 LEU A  49
ASP A  97
PHE A  18
PHE A 352
ASP A 316
 None
None
None
None
GOL  A1548 (-3.5A)
 1.23A 3m0wE-4aieA:
undetectable
3m0wF-4aieA:
undetectable
3m0wG-4aieA:
undetectable
3m0wH-4aieA:
undetectable		 3m0wE-4aieA:
11.71
3m0wF-4aieA:
11.71
3m0wG-4aieA:
11.71
3m0wH-4aieA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kr9 PROBABLE TRNA
SULFURTRANSFERASE

(Thermotoga
maritima) 		PF02568
(ThiI)
PF02926
(THUMP) 		5 LEU A  61
ASP A  58
ILE A  67
CYH A 165
ASP A 161
 None
 1.49A 3m0wE-4kr9A:
undetectable
3m0wF-4kr9A:
undetectable
3m0wG-4kr9A:
undetectable
3m0wH-4kr9A:
undetectable		 3m0wE-4kr9A:
12.24
3m0wF-4kr9A:
12.24
3m0wG-4kr9A:
12.24
3m0wH-4kr9A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ole NEXT TO BRCA1 GENE 1
PROTEIN

(Homo sapiens) 		PF16158
(N_BRCA1_IG) 		5 LEU A 380
ILE A 476
CYH A 474
ASP A 428
SER A 423
 None
 1.48A 3m0wE-4oleA:
undetectable
3m0wF-4oleA:
undetectable
3m0wG-4oleA:
undetectable
3m0wH-4oleA:
undetectable		 3m0wE-4oleA:
18.80
3m0wF-4oleA:
18.80
3m0wG-4oleA:
18.80
3m0wH-4oleA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1z CYP17A1 PROTEIN

(Danio rerio) 		PF00067
(p450) 		5 LEU A 364
SER A 325
ILE A 339
PHE A 428
PHE A 423
 None
 1.46A 3m0wE-4r1zA:
0.0
3m0wF-4r1zA:
0.1
3m0wG-4r1zA:
0.0
3m0wH-4r1zA:
undetectable		 3m0wE-4r1zA:
14.50
3m0wF-4r1zA:
14.50
3m0wG-4r1zA:
14.50
3m0wH-4r1zA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u5a SPOROZOITE MICRONEME
PROTEIN ESSENTIAL
FOR CELL TRAVERSAL

(Plasmodium
berghei) 		no annotation 5 LEU A  57
ASP A  60
PHE A 115
ILE A 138
CYH A 142
 None
 1.25A 3m0wE-4u5aA:
1.7
3m0wF-4u5aA:
1.8
3m0wG-4u5aA:
1.8
3m0wH-4u5aA:
1.8		 3m0wE-4u5aA:
19.80
3m0wF-4u5aA:
19.80
3m0wG-4u5aA:
19.80
3m0wH-4u5aA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhv U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP3

(Saccharomyces
cerevisiae) 		PF06544
(DUF1115) 		5 LEU A 451
SER A 460
ILE A 379
PHE A 441
PHE A 437
 None
 1.27A 3m0wE-4yhvA:
undetectable
3m0wF-4yhvA:
undetectable
3m0wG-4yhvA:
undetectable
3m0wH-4yhvA:
undetectable		 3m0wE-4yhvA:
23.03
3m0wF-4yhvA:
23.03
3m0wG-4yhvA:
23.03
3m0wH-4yhvA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR

(Homo sapiens) 		no annotation 5 LEU B 276
ASP B 275
SER B 296
ILE B 305
SER B 170
 None
None
None
None
TCR  B 609 (-2.8A)
 1.35A 3m0wE-5fbhB:
undetectable
3m0wF-5fbhB:
undetectable
3m0wG-5fbhB:
undetectable
3m0wH-5fbhB:
undetectable		 3m0wE-5fbhB:
9.68
3m0wF-5fbhB:
9.68
3m0wG-5fbhB:
9.68
3m0wH-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqr LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE TDR

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		5 LEU B 134
ASP B 135
ILE B 125
PHE B 141
SER B 187
 None
NAG  B 702 (-4.1A)
None
None
None
 1.40A 3m0wE-5gqrB:
undetectable
3m0wF-5gqrB:
undetectable
3m0wG-5gqrB:
undetectable
3m0wH-5gqrB:
undetectable		 3m0wE-5gqrB:
9.56
3m0wF-5gqrB:
9.56
3m0wG-5gqrB:
9.56
3m0wH-5gqrB:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa) 		PF04453
(OstA_C) 		5 ASP A 593
PHE A 572
PHE A 611
ASP A  57
SER A  56
 None
None
None
None
C8E  A 702 ( 4.9A)
 1.37A 3m0wE-5ivaA:
undetectable
3m0wF-5ivaA:
undetectable
3m0wG-5ivaA:
undetectable
3m0wH-5ivaA:
undetectable		 3m0wE-5ivaA:
11.73
3m0wF-5ivaA:
11.73
3m0wG-5ivaA:
11.73
3m0wH-5ivaA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jif HEMAGGLUTININ-ESTERA
SE

(Murine
coronavirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		5 LEU A 147
SER A  85
PHE A  86
ILE A 283
PHE A  91
 None
None
None
None
NAG  A 803 ( 4.8A)
 1.28A 3m0wE-5jifA:
undetectable
3m0wF-5jifA:
undetectable
3m0wG-5jifA:
undetectable
3m0wH-5jifA:
undetectable		 3m0wE-5jifA:
14.25
3m0wF-5jifA:
14.25
3m0wG-5jifA:
14.25
3m0wH-5jifA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		5 SER A 368
ILE A 413
PHE A 420
ASP A 346
SER A 363
 None
 1.22A 3m0wE-5kshA:
undetectable
3m0wF-5kshA:
undetectable
3m0wG-5kshA:
undetectable
3m0wH-5kshA:
undetectable		 3m0wE-5kshA:
11.32
3m0wF-5kshA:
11.32
3m0wG-5kshA:
11.32
3m0wH-5kshA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4x UDP-GLUCOSE
6-DEHYDROGENASE

(Homo sapiens) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		5 LEU A 357
ASP A 359
SER A 316
PHE A 314
ILE A 353
 None
 1.41A 3m0wE-5w4xA:
undetectable
3m0wF-5w4xA:
undetectable
3m0wG-5w4xA:
undetectable
3m0wH-5w4xA:
undetectable		 3m0wE-5w4xA:
12.33
3m0wF-5w4xA:
12.33
3m0wG-5w4xA:
12.33
3m0wH-5w4xA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 5

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		5 LEU B 111
ASP B 109
SER B 145
ILE B 150
ASP B  72
 None
 1.12A 3m0wE-5y3rB:
undetectable
3m0wF-5y3rB:
undetectable
3m0wG-5y3rB:
undetectable
3m0wH-5y3rB:
undetectable		 3m0wE-5y3rB:
11.45
3m0wF-5y3rB:
11.45
3m0wG-5y3rB:
11.45
3m0wH-5y3rB:
11.45