SIMILAR PATTERNS OF AMINO ACIDS FOR 3LW5_B_PQNB5002
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g6o | CAG-ALPHA (Helicobacterpylori) |
PF00437(T2SSE) | 5 | PHE A 84ARG A 29ALA A 109LEU A 28ALA A 31 | None | 1.11A | 3lw5B-1g6oA:undetectable | 3lw5B-1g6oA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gl9 | REVERSE GYRASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 5 | PHE B 789SER B 790ALA B 798LEU B 879ALA B 783 | None | 1.43A | 3lw5B-1gl9B:0.0 | 3lw5B-1gl9B:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iho | PANTOATE--BETA-ALANINE LIGASE (Escherichiacoli) |
PF02569(Pantoate_ligase) | 5 | ILE A 177PHE A 238ALA A 272LEU A 274ALA A 267 | None | 1.21A | 3lw5B-1ihoA:undetectable | 3lw5B-1ihoA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iq7 | OVOTRANSFERRIN (Gallus gallus) |
PF00405(Transferrin) | 5 | MET A 468ARG A 460TRP A 464ALA A 457ALA A 462 | None | 1.23A | 3lw5B-1iq7A:undetectable | 3lw5B-1iq7A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ocm | MALONAMIDASE E2 (Bradyrhizobiumjaponicum) |
PF01425(Amidase) | 5 | ILE A 157PHE A 213ALA A 401LEU A 400ALA A 201 | None | 1.20A | 3lw5B-1ocmA:0.0 | 3lw5B-1ocmA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qo4 | PEROXIDASE (Arabidopsisthaliana) |
PF00141(peroxidase) | 5 | ILE A 138ARG A 123ALA A 102LEU A 101ALA A 51 | None | 1.42A | 3lw5B-1qo4A:undetectable | 3lw5B-1qo4A:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 1 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ILE A 203PHE A 235SER A 225ALA A 238LEU A 237 | None | 1.33A | 3lw5B-1tqyA:0.1 | 3lw5B-1tqyA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujj | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA1 (Homo sapiens) |
PF00790(VHS) | 5 | ILE A 64PHE A 90ALA A 47LEU A 51ALA A 52 | None | 1.32A | 3lw5B-1ujjA:undetectable | 3lw5B-1ujjA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e27 | ANTI-CIGUATOXINANTIBODY, HEAVYCHAIN (Mus musculus) |
PF07686(V-set) | 5 | ILE H 48SER H 113ALA H 16LEU H 823ALA H 83 | None | 1.41A | 3lw5B-2e27H:undetectable | 3lw5B-2e27H:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ewm | (S)-1-PHENYLETHANOLDEHYDROGENASE (Azoarcus) |
PF13561(adh_short_C2) | 5 | ILE A 162ARG A 135ALA A 232LEU A 227ALA A 224 | None | 1.25A | 3lw5B-2ewmA:undetectable | 3lw5B-2ewmA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f43 | ATP SYNTHASE ALPHACHAIN, MITOCHONDRIAL (Rattusnorvegicus) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 5 | ILE A 115MET A 62PHE A 76ALA A 240LEU A 242 | None | 1.35A | 3lw5B-2f43A:undetectable | 3lw5B-2f43A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9y | ACETYL-COACARBOXYLASE,CARBOXYLTRANSFERASEALPHA CHAINACETYL-COENZYME ACARBOXYLASE CARBOXYLTRANSFERASE SUBUNITBETA (Escherichiacoli) |
PF01039(Carboxyl_trans)PF03255(ACCA) | 5 | ILE A 264SER B 209ALA A 210LEU A 209ALA B 178 | None | 1.33A | 3lw5B-2f9yA:undetectable | 3lw5B-2f9yA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gai | DNA TOPOISOMERASE I (Thermotogamaritima) |
PF01131(Topoisom_bac)PF01751(Toprim) | 5 | PHE A 260SER A 261ALA A 269LEU A 360ALA A 254 | None | 1.40A | 3lw5B-2gaiA:undetectable | 3lw5B-2gaiA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2q | FORMYLTETRAHYDROFOLATE DEHYDROGENASE (Rattusnorvegicus) |
PF00171(Aldedh) | 5 | ILE A 506PHE A 530ARG A 491ALA A 616ALA A 493 | None | 1.41A | 3lw5B-2o2qA:undetectable | 3lw5B-2o2qA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q27 | OXALYL-COADECARBOXYLASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ILE A 314PHE A 234SER A 237ALA A 209LEU A 208 | None | 1.34A | 3lw5B-2q27A:undetectable | 3lw5B-2q27A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4y | URIDYLATE KINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | ILE A 33PHE A 218ARG A 227LEU A 226ALA A 225 | None | 1.30A | 3lw5B-2v4yA:undetectable | 3lw5B-2v4yA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vd5 | DMPK PROTEIN (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 196PHE A 339ALA A 172LEU A 176ALA A 177 | None | 1.43A | 3lw5B-2vd5A:undetectable | 3lw5B-2vd5A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5d | PROBABLEAMINOTRANSFERASE (Pseudomonasaeruginosa) |
PF00155(Aminotran_1_2) | 5 | ILE A 39PHE A 394ARG A 315LEU A 314ALA A 317 | None | 1.16A | 3lw5B-2x5dA:undetectable | 3lw5B-2x5dA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvi | ANKYRIN-1 (Homo sapiens) |
PF00531(Death) | 5 | ILE A1480PHE A1428ALA A1450LEU A1451ALA A1423 | None | 1.31A | 3lw5B-2yviA:undetectable | 3lw5B-2yviA:10.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvq | CARBAMOYL-PHOSPHATESYNTHASE (Homo sapiens) |
PF02142(MGS) | 5 | ILE A1432PHE A1374ALA A1474LEU A1381ALA A1378 | None | 1.30A | 3lw5B-2yvqA:undetectable | 3lw5B-2yvqA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | ILE A 159ARG A 193ALA A 197LEU A 196ALA A 176 | NoneVDX A 501 (-3.5A)NoneNoneNone | 1.27A | 3lw5B-2zbzA:undetectable | 3lw5B-2zbzA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | ILE A 159PHE A 172ALA A 197LEU A 196ALA A 176 | None | 1.36A | 3lw5B-2zbzA:undetectable | 3lw5B-2zbzA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6k | PUTATIVEAMINOTRANSFERASE (Corynebacteriumdiphtheriae) |
PF12897(Aminotran_MocR) | 5 | PHE A 249TRP A 82ALA A 83LEU A 88ALA A 267 | None | 1.27A | 3lw5B-3d6kA:undetectable | 3lw5B-3d6kA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ILE A 23PHE A 132ALA A 143LEU A 142ALA A 135 | None4MD A 401 (-4.6A)NoneNoneNone | 1.06A | 3lw5B-3da2A:undetectable | 3lw5B-3da2A:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eb2 | PUTATIVEDIHYDRODIPICOLINATESYNTHETASE (Rhodopseudomonaspalustris) |
PF00701(DHDPS) | 5 | MET A 198ARG A 228ALA A 226LEU A 223ALA A 232 | None | 1.37A | 3lw5B-3eb2A:undetectable | 3lw5B-3eb2A:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ei8 | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Arabidopsisthaliana) |
PF00155(Aminotran_1_2) | 5 | PHE A 274SER A 267TRP A 281ALA A 311ALA A 319 | NonePLP A 433 (-2.5A)NoneNoneNone | 1.30A | 3lw5B-3ei8A:undetectable | 3lw5B-3ei8A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gc6 | ECTO-NAD+GLYCOHYDROLASE (CD38MOLECULE) (Bos taurus) |
PF02267(Rib_hydrolayse) | 5 | ILE A 213SER A 243ALA A 230LEU A 200ALA A 207 | SO4 A 281 (-3.9A)NoneNoneNoneNone | 1.27A | 3lw5B-3gc6A:undetectable | 3lw5B-3gc6A:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrr | AFLATOXINBIOSYNTHESISPOLYKETIDE SYNTHASE (Aspergillusparasiticus) |
PF14765(PS-DH) | 5 | ILE A1613PHE A1526SER A1531ALA A1537LEU A1580 | None | 1.31A | 3lw5B-3hrrA:undetectable | 3lw5B-3hrrA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ijl | MUCONATECYCLOISOMERASE (Bacteroidesthetaiotaomicron) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | MET A 327SER A 90ALA A 139LEU A 299ALA A 333 | DGL A 385 ( 3.6A)NoneNoneNoneNone | 1.32A | 3lw5B-3ijlA:undetectable | 3lw5B-3ijlA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7a | 40S RIBOSOMALPROTEIN US2 (Plasmodiumfalciparum) |
PF00318(Ribosomal_S2) | 5 | ILE C 160MET C 200PHE C 201ALA C 90ALA C 85 | None | 1.38A | 3lw5B-3j7aC:undetectable | 3lw5B-3j7aC:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jyf | 2',3'-CYCLICNUCLEOTIDE2'-PHOSPHODIESTERASE/3'-NUCLEOTIDASEBIFUNCTIONALPERIPLASMIC PROTEIN (Klebsiellapneumoniae) |
PF00149(Metallophos) | 5 | MET A 272PHE A 240ALA A 258LEU A 265ALA A 270 | None | 1.24A | 3lw5B-3jyfA:undetectable | 3lw5B-3jyfA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ILE A 22PHE A 131ALA A 142LEU A 141ALA A 134 | NoneAZM A 264 (-4.4A)NoneNoneNone | 0.98A | 3lw5B-3ml5A:undetectable | 3lw5B-3ml5A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p2c | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesovatus) |
PF06824(Glyco_hydro_125) | 5 | SER A 308ARG A 292ALA A 315LEU A 291ALA A 294 | None | 1.42A | 3lw5B-3p2cA:undetectable | 3lw5B-3p2cA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdk | PHOSPHOGLUCOSAMINEMUTASE (Bacillusanthracis) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | ILE A 264PHE A 239ALA A 177LEU A 237ALA A 238 | None | 1.33A | 3lw5B-3pdkA:undetectable | 3lw5B-3pdkA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl6 | PURINE NUCLEOSIDEPHOSPHORYLASE (Entamoebahistolytica) |
PF01048(PNP_UDP_1) | 5 | ILE A 93PHE A 82ALA A 188LEU A 189ALA A 78 | None | 1.40A | 3lw5B-3tl6A:undetectable | 3lw5B-3tl6A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tot | GLUTATHIONES-TRANSFERASEPROTEIN (Ralstoniasolanacearum) |
PF13410(GST_C_2)PF13417(GST_N_3) | 5 | ILE A 6SER A 76ALA A 22LEU A 21ALA A 72 | None | 1.43A | 3lw5B-3totA:undetectable | 3lw5B-3totA:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ILE A 143PHE A 156SER A 218ALA A 115LEU A 147 | None | 1.24A | 3lw5B-3uyqA:undetectable | 3lw5B-3uyqA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfp | POLY A POLYMERASE (Aquifexaeolicus;syntheticconstruct) |
PF01743(PolyA_pol)PF01966(HD)PF12627(PolyA_pol_RNAbd) | 5 | PHE A 113SER A 114ALA A 65LEU A 70ALA A 71 | None | 1.42A | 3lw5B-3wfpA:undetectable | 3lw5B-3wfpA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f85 | GERANYL DIPHOSPHATE2-C-METHYLTRANSFERASE (Streptomyceslasaliensis) |
PF02353(CMAS) | 5 | ILE A 295PHE A 198ARG A 200ALA A 175LEU A 199 | None | 1.40A | 3lw5B-4f85A:undetectable | 3lw5B-4f85A:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fo0 | ACTIN-RELATEDPROTEIN 8 (Homo sapiens) |
PF00022(Actin) | 5 | ILE A 252PHE A 622ARG A 617LEU A 616ALA A 620 | None | 1.41A | 3lw5B-4fo0A:undetectable | 3lw5B-4fo0A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h08 | PUTATIVE HYDROLASE (Bacteroidesthetaiotaomicron) |
PF00657(Lipase_GDSL) | 5 | ILE A 125SER A 31TRP A 30ALA A 84LEU A 85 | None | 1.41A | 3lw5B-4h08A:undetectable | 3lw5B-4h08A:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE BETA CHAIN (Pseudomonas) |
PF01804(Penicil_amidase) | 5 | ILE B 231SER B 483ALA B 19LEU B 18ALA B 65 | None | 1.42A | 3lw5B-4hstB:undetectable | 3lw5B-4hstB:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqg | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Polaromonas sp.JS666) |
no annotation | 5 | ILE C 164PHE C 71ALA C 83LEU C 84ALA C 123 | None | 1.37A | 3lw5B-4iqgC:undetectable | 3lw5B-4iqgC:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0k | TANNASE (Lactobacillusplantarum) |
no annotation | 5 | ILE A 206TRP A 447ALA A 444LEU A 445ALA A 417 | EGR A 501 (-4.0A)NoneNoneNoneNone | 1.39A | 3lw5B-4j0kA:undetectable | 3lw5B-4j0kA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j5t | MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE (Saccharomycescerevisiae) |
PF03200(Glyco_hydro_63)PF16923(Glyco_hydro_63N) | 5 | ILE A 75PHE A 376SER A 414ALA A 408LEU A 407 | None | 1.33A | 3lw5B-4j5tA:undetectable | 3lw5B-4j5tA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lcm | TRANSESTERASE (Aspergillusterreus) |
PF00144(Beta-lactamase) | 5 | ILE A 215PHE A 384ARG A 73ALA A 75LEU A 74 | None | 1.26A | 3lw5B-4lcmA:undetectable | 3lw5B-4lcmA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lqk | PROTEIN A46 (Vaccinia virus) |
no annotation | 5 | ILE C 160PHE C 91SER C 90ALA C 96LEU C 95 | None | 1.23A | 3lw5B-4lqkC:undetectable | 3lw5B-4lqkC:11.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mi2 | PUTATIVE ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | ILE A 103PHE A 65ALA A 118LEU A 122ALA A 123 | None | 1.35A | 3lw5B-4mi2A:undetectable | 3lw5B-4mi2A:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mx2 | ADENYLOSUCCINATELYASE (Leishmaniadonovani) |
PF00206(Lyase_1)PF08328(ASL_C) | 5 | ILE A 213PHE A 333ALA A 382LEU A 386ALA A 298 | None | 1.43A | 3lw5B-4mx2A:1.5 | 3lw5B-4mx2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn3 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 5 | ILE A 160MET A 220PHE A 222ALA A 201LEU A 202 | None | 1.29A | 3lw5B-4nn3A:undetectable | 3lw5B-4nn3A:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6z | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumfalciparum) |
PF00464(SHMT) | 5 | ILE A 238ARG A 80ALA A 282LEU A 285ALA A 81 | None | 1.23A | 3lw5B-4o6zA:undetectable | 3lw5B-4o6zA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozq | CHIMERA OFMALTOSE-BINDINGPERIPLASMIC PROTEINAND KINESIN FAMILYMEMBER 14 PROTEIN (Escherichiacoli;Mus musculus) |
PF00225(Kinesin)PF13416(SBP_bac_8) | 5 | ILE A 580PHE A 471ALA A 464LEU A 467ALA A 470 | None | 1.11A | 3lw5B-4ozqA:1.3 | 3lw5B-4ozqA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pls | ARM00010 (syntheticconstruct) |
PF00514(Arm) | 5 | ILE A 46SER A 63ALA A 57LEU A 58ALA A 73 | None | 1.43A | 3lw5B-4plsA:undetectable | 3lw5B-4plsA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ILE A 22PHE A 131ALA A 142LEU A 141ALA A 134 | None | 1.06A | 3lw5B-4qk3A:undetectable | 3lw5B-4qk3A:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rih | GLYCOSYL TRANSFERASEHOMOLOG,GLYCOSYLTRANSFERASE (Streptomycescyanogenus;Streptomycesfradiae) |
PF06722(DUF1205) | 5 | ILE A 3MET A 91ALA A 98LEU A 99ALA A 119 | None | 1.32A | 3lw5B-4rihA:undetectable | 3lw5B-4rihA:19.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rku | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Pisum sativum) |
PF00223(PsaA_PsaB) | 7 | MET A 691PHE A 692SER A 695ARG A 697TRP A 700ALA A 724LEU A 725 | CLA A9013 ( 3.6A)PQN A5001 (-3.6A)PQN A5001 (-3.5A)NonePQN A5001 ( 3.4A)PQN A5001 (-3.4A)PQN A5001 ( 3.7A) | 0.77A | 3lw5B-4rkuA:12.2 | 3lw5B-4rkuA:45.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rku | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Pisum sativum) |
PF00223(PsaA_PsaB) | 6 | ILE B 21MET B 662PHE B 663SER B 666LEU B 700ALA B 705 | CLA A1131 ( 4.4A)CLA B9023 ( 3.3A)PQN B5002 ( 4.3A)PQN B5002 (-3.2A)PQN B5002 (-3.7A)PQN B5002 (-3.4A) | 1.48A | 3lw5B-4rkuB:15.5 | 3lw5B-4rkuB:98.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rku | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Pisum sativum) |
PF00223(PsaA_PsaB) | 9 | ILE B 25MET B 662PHE B 663SER B 666ARG B 668TRP B 671ALA B 699LEU B 700ALA B 705 | CLA B1201 ( 4.7A)CLA B9023 ( 3.3A)PQN B5002 ( 4.3A)PQN B5002 (-3.2A)NonePQN B5002 ( 3.3A)PQN B5002 (-3.2A)PQN B5002 (-3.7A)PQN B5002 (-3.4A) | 0.59A | 3lw5B-4rkuB:15.5 | 3lw5B-4rkuB:98.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rku | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Pisum sativum) |
PF00223(PsaA_PsaB) | 7 | ILE B 25TRP B 667ARG B 668TRP B 671ALA B 699LEU B 700ALA B 705 | CLA B1201 ( 4.7A)NoneNonePQN B5002 ( 3.3A)PQN B5002 (-3.2A)PQN B5002 (-3.7A)PQN B5002 (-3.4A) | 1.27A | 3lw5B-4rkuB:15.5 | 3lw5B-4rkuB:98.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv7 | DIADENYLATE CYCLASE (Listeriamonocytogenes) |
PF02457(DisA_N) | 5 | ILE A 44SER A 129ARG A 103ALA A 30ALA A 107 | NoneNoneATP A1001 (-3.5A)NoneNone | 1.39A | 3lw5B-4rv7A:undetectable | 3lw5B-4rv7A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqv | BIFUNCTIONAL2',3'-CYCLICNUCLEOTIDE2'-PHOSPHODIESTERASE/3'-NUCLEOTIDASEPERIPLASMICPRECURSOR PROTEIN (Yersinia pestis) |
PF00149(Metallophos) | 5 | MET A 295PHE A 263ALA A 281LEU A 288ALA A 293 | None | 1.32A | 3lw5B-5eqvA:undetectable | 3lw5B-5eqvA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ex1 | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECYCLOPHILIN TYPE (Hirschiabaltica) |
PF00160(Pro_isomerase) | 5 | ILE A 32MET A 153PHE A 183ALA A 61ALA A 56 | None | 1.36A | 3lw5B-5ex1A:undetectable | 3lw5B-5ex1A:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 5 | ILE X 21PHE X 129ALA X 140LEU X 139ALA X 132 | None | 1.07A | 3lw5B-5eztX:undetectable | 3lw5B-5eztX:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1k | GEM-ASSOCIATEDPROTEIN 5 (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 5 | ILE A 628SER A 657TRP A 667ALA A 669ALA A 601 | None | 1.40A | 3lw5B-5h1kA:undetectable | 3lw5B-5h1kA:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3k | SLR0280 PROTEIN (Synechocystissp. PCC 6803) |
no annotation | 5 | ILE A 506PHE A 520SER A 521LEU A 558ALA A 515 | None | 1.25A | 3lw5B-5h3kA:undetectable | 3lw5B-5h3kA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hot | INTEGRASE (Humanimmunodeficiencyvirus 1) |
PF00552(IN_DBD_C)PF00665(rve) | 5 | ILE A 84TRP A 132ALA A 98LEU A 101ALA A 105 | None | 1.40A | 3lw5B-5hotA:undetectable | 3lw5B-5hotA:16.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j4r | WELO5 (Hapalosiphonwelwitschii) |
no annotation | 5 | ILE A 127PHE A 279SER A 185LEU A 188ALA A 278 | None | 1.35A | 3lw5B-5j4rA:undetectable | 3lw5B-5j4rA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l51 | (-)-MENTHONE:(+)-NEOMENTHOL REDUCTASE (Mentha xpiperita) |
PF00106(adh_short)PF13561(adh_short_C2) | 5 | ILE A 172SER A 191ARG A 256ALA A 253ALA A 269 | None | 1.40A | 3lw5B-5l51A:undetectable | 3lw5B-5l51A:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li8 | PUTATIVE CYTOCHROMEP450 126 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | ILE A 290PHE A 145ARG A 259ALA A 151ALA A 263 | None | 1.32A | 3lw5B-5li8A:undetectable | 3lw5B-5li8A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m23 | WD REPEAT-CONTAININGPROTEIN 5 (Homo sapiens) |
PF00400(WD40) | 5 | ILE A 285PHE A 219SER A 189LEU A 230ALA A 232 | None | 1.34A | 3lw5B-5m23A:undetectable | 3lw5B-5m23A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mbh | BETA SUBUNIT OFPHOTOACTIVATEDADENYLYL CYCLASE (Beggiatoa sp.PS) |
PF00211(Guanylate_cyc)PF04940(BLUF) | 5 | ILE A 188PHE A 292ALA A 329LEU A 290ALA A 291 | None | 1.29A | 3lw5B-5mbhA:undetectable | 3lw5B-5mbhA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwn | TYPE VI SECRETIONPROTEIN (Escherichiacoli) |
PF05936(T6SS_VasE) | 5 | PHE A 49ARG A 63ALA A 46LEU A 64ALA A 61 | None | 1.42A | 3lw5B-5mwnA:undetectable | 3lw5B-5mwnA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Synechocystissp. PCC 6803) |
no annotation | 7 | MET 1 684PHE 1 685SER 1 688ARG 1 690TRP 1 693ALA 1 717LEU 1 718 | CLA 1 802 ( 3.2A)PQN 1 842 (-3.8A)PQN 1 842 (-3.4A)NonePQN 1 842 ( 3.3A)PQN 1 842 (-3.2A)PQN 1 842 ( 3.6A) | 0.64A | 3lw5B-5oy01:11.2 | 3lw5B-5oy01:7.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Synechocystissp. PCC 6803) |
no annotation | 5 | ILE b 21MET b 659PHE b 660SER b 663ALA b 702 | NoneCLA b1807 ( 3.2A)PQN b1844 ( 4.2A)PQN b1844 (-3.7A)PQN b1844 (-3.1A) | 1.33A | 3lw5B-5oy0b:12.1 | 3lw5B-5oy0b:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Synechocystissp. PCC 6803) |
no annotation | 9 | ILE b 25MET b 659PHE b 660SER b 663ARG b 665TRP b 668ALA b 696LEU b 697ALA b 702 | LMG b1851 ( 4.9A)CLA b1807 ( 3.2A)PQN b1844 ( 4.2A)PQN b1844 (-3.7A)NonePQN b1844 ( 3.4A)PQN b1844 (-3.2A)PQN b1844 ( 3.8A)PQN b1844 (-3.1A) | 0.81A | 3lw5B-5oy0b:12.1 | 3lw5B-5oy0b:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Synechocystissp. PCC 6803) |
no annotation | 6 | TRP b 664ARG b 665TRP b 668ALA b 696LEU b 697ALA b 702 | NoneNonePQN b1844 ( 3.4A)PQN b1844 (-3.2A)PQN b1844 ( 3.8A)PQN b1844 (-3.1A) | 1.44A | 3lw5B-5oy0b:12.1 | 3lw5B-5oy0b:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u09 | CANNABINOID RECEPTOR1,GLGA GLYCOGENSYNTHASE (Homo sapiens;Pyrococcusabyssi) |
PF00001(7tm_1)PF00534(Glycos_transf_1) | 5 | ILE A 353PHE A 155SER A 152ALA A 342ALA A 210 | None | 1.25A | 3lw5B-5u09A:undetectable | 3lw5B-5u09A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4s | PUTATIVE SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF00106(adh_short) | 5 | ILE A 126ARG A 28ALA A 24LEU A 25ALA A 30 | None | 1.23A | 3lw5B-5u4sA:undetectable | 3lw5B-5u4sA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj1 | DNA TOPOISOMERASE 1 (Mycobacteriumtuberculosis) |
no annotation | 5 | PHE A 322SER A 323ALA A 331LEU A 419ALA A 316 | None | 1.37A | 3lw5B-5uj1A:undetectable | 3lw5B-5uj1A:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 5 | ILE A 557PHE A 610SER A 680ALA A 672ALA A 603 | None | 1.29A | 3lw5B-5ve8A:undetectable | 3lw5B-5ve8A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vol | PUTATIVE ESTERASE (Bacteroidesintestinalis) |
PF00756(Esterase) | 5 | ILE A 133SER A 152TRP A 270ALA A 158LEU A 63 | None | 1.33A | 3lw5B-5volA:undetectable | 3lw5B-5volA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxc | CITRATE LYASESUBUNIT BETA-LIKEPROTEIN,MITOCHONDRIAL (Homo sapiens) |
no annotation | 5 | ILE A 222PHE A 284SER A 285ARG A 259ALA A 262 | None | 1.20A | 3lw5B-5vxcA:undetectable | 3lw5B-5vxcA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wya | ISOLEUCINE2-EPIMERASE (Lactobacillusbuchneri) |
PF00202(Aminotran_3) | 5 | ILE A 327PHE A 111ALA A 98LEU A 97ALA A 290 | None | 1.25A | 3lw5B-5wyaA:undetectable | 3lw5B-5wyaA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7v | NUCLEOSOME ASSEMBLYPROTEIN (Plasmodiumfalciparum) |
PF00956(NAP) | 5 | ILE A 166PHE A 123TRP A 80ALA A 81LEU A 101 | None | 1.23A | 3lw5B-5x7vA:undetectable | 3lw5B-5x7vA:13.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xav | INTRACELLULARPOLYHYDROXYALKANOATESYNTHASE (Chromobacteriumsp. USM2) |
PF07167(PhaC_N) | 5 | ILE A 430MET A 285PHE A 312LEU A 297ALA A 315 | None | 1.25A | 3lw5B-5xavA:undetectable | 3lw5B-5xavA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmr | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumvivax) |
no annotation | 5 | ILE A 238ARG A 80ALA A 282LEU A 285ALA A 81 | None | 1.26A | 3lw5B-5xmrA:undetectable | 3lw5B-5xmrA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxg | PILUS ASSEMBLYPROTEIN (Lactobacillusrhamnosus) |
no annotation | 5 | ILE A 264PHE A 292SER A 277ALA A 253LEU A 254 | None | 1.22A | 3lw5B-5yxgA:undetectable | 3lw5B-5yxgA:7.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bfi | VIN1 (Oscarellapearsei) |
no annotation | 5 | ILE A 448PHE A 403ALA A 385LEU A 386ALA A 407 | None | 1.34A | 3lw5B-6bfiA:3.2 | 3lw5B-6bfiA:8.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byn | WD REPEAT-CONTAININGPROTEIN 5 (Homo sapiens) |
no annotation | 5 | ILE W 285PHE W 219SER W 189LEU W 230ALA W 232 | None | 1.35A | 3lw5B-6bynW:undetectable | 3lw5B-6bynW:9.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0w | HISTONE H3-LIKECENTROMERIC PROTEINAHISTONE H4 (Homo sapiens) |
no annotation | 5 | PHE A 106ARG B 36ALA B 33LEU B 37ALA B 38 | PHE A 106 ( 1.3A)ARG B 36 ( 0.6A)ALA B 33 ( 0.0A)LEU B 37 ( 0.6A)ALA B 38 ( 0.0A) | 1.30A | 3lw5B-6c0wA:undetectable | 3lw5B-6c0wA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cc2 | CELL DIVISIONCONTROL PROTEIN 45CDC45 PUTATIVE (Entamoebahistolytica) |
no annotation | 5 | ILE A 413PHE A 468ALA A 471LEU A 470ALA A 451 | PEG A 616 (-4.9A)NoneNoneNoneNone | 1.42A | 3lw5B-6cc2A:undetectable | 3lw5B-6cc2A:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cip | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Moorellathermoacetica) |
no annotation | 5 | ILE A 484SER A 617ARG A 528ALA A 524ALA A 531 | None | 0.95A | 3lw5B-6cipA:2.3 | 3lw5B-6cipA:7.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6co7 | PREDICTED PROTEIN (Nematostellavectensis) |
no annotation | 5 | ILE A 526SER A 635ALA A 641LEU A 617ALA A 621 | None | 1.27A | 3lw5B-6co7A:2.9 | 3lw5B-6co7A:6.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6egt | GLYCOPROTEIN (Rift Valleyfeverphlebovirus) |
no annotation | 5 | ILE A1085SER A 908ALA A 992LEU A 981ALA A 914 | None | 1.34A | 3lw5B-6egtA:undetectable | 3lw5B-6egtA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Cyanidioschyzonmerolae) |
no annotation | 6 | MET A 681PHE A 682ARG A 687TRP A 690ALA A 714LEU A 715 | PQN A2001 ( 3.3A)PQN A2001 (-4.3A)NonePQN A2001 ( 3.2A)PQN A2001 (-3.2A)PQN A2001 (-3.7A) | 0.77A | 3lw5B-6fosA:11.4 | 3lw5B-6fosA:7.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Cyanidioschyzonmerolae) |
no annotation | 6 | PHE A 682SER A 685ARG A 687TRP A 690ALA A 714LEU A 715 | PQN A2001 (-4.3A)PQN A2001 (-4.4A)NonePQN A2001 ( 3.2A)PQN A2001 (-3.2A)PQN A2001 (-3.7A) | 0.94A | 3lw5B-6fosA:11.4 | 3lw5B-6fosA:7.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Cyanidioschyzonmerolae) |
no annotation | 5 | ILE B 21MET B 660PHE B 661SER B 664ALA B 703 | NonePQN B2002 ( 3.2A)PQN B2002 ( 4.3A)CLA B1023 (-4.5A)PQN B2002 (-3.4A) | 1.34A | 3lw5B-6fosB:11.5 | 3lw5B-6fosB:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Cyanidioschyzonmerolae) |
no annotation | 8 | ILE B 25MET B 660PHE B 661SER B 664ARG B 666TRP B 669ALA B 697LEU B 698 | CLA B1201 ( 4.6A)PQN B2002 ( 3.2A)PQN B2002 ( 4.3A)CLA B1023 (-4.5A)NonePQN B2002 (-3.3A)PQN B2002 (-3.1A)PQN B2002 (-3.6A) | 0.96A | 3lw5B-6fosB:11.5 | 3lw5B-6fosB:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Cyanidioschyzonmerolae) |
no annotation | 8 | ILE B 25MET B 660PHE B 661SER B 664TRP B 669ALA B 697LEU B 698ALA B 703 | CLA B1201 ( 4.6A)PQN B2002 ( 3.2A)PQN B2002 ( 4.3A)CLA B1023 (-4.5A)PQN B2002 (-3.3A)PQN B2002 (-3.1A)PQN B2002 (-3.6A)PQN B2002 (-3.4A) | 0.86A | 3lw5B-6fosB:11.5 | 3lw5B-6fosB:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Cyanidioschyzonmerolae) |
no annotation | 5 | SER B 664TRP B 665ARG B 666TRP B 669ALA B 697 | CLA B1023 (-4.5A)NoneNonePQN B2002 (-3.3A)PQN B2002 (-3.1A) | 1.40A | 3lw5B-6fosB:11.5 | 3lw5B-6fosB:11.09 |