SIMILAR PATTERNS OF AMINO ACIDS FOR 3LTW_A_HLZA300

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avg TRIABIN

(Meccus
pallidipennis) 		PF03973
(Triabin) 		4 PHE I  21
TYR I  80
VAL I 109
PHE I  15
 None
 1.33A 3ltwA-1avgI:
undetectable		 3ltwA-1avgI:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avg TRIABIN

(Meccus
pallidipennis) 		PF03973
(Triabin) 		4 PHE I  82
TYR I  80
VAL I 109
PHE I  21
 None
 1.22A 3ltwA-1avgI:
undetectable		 3ltwA-1avgI:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bkd SON OF SEVENLESS-1

(Homo sapiens) 		PF00617
(RasGEF)
PF00618
(RasGEF_N) 		4 PHE S 634
TYR S 631
CYH S 635
PHE S 627
 None
 0.91A 3ltwA-1bkdS:
undetectable		 3ltwA-1bkdS:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1by9 REGULATORY PROTEIN
E2

(Alphapapillomavirus
9) 		PF00511
(PPV_E2_C) 		4 PHE A 344
TYR A 310
VAL A 331
PHE A 303
 None
 1.37A 3ltwA-1by9A:
undetectable		 3ltwA-1by9A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjw PROTEIN (SEROTONIN
N-ACETYLTRANSFERASE)

(Ovis aries) 		PF00583
(Acetyltransf_1) 		4 PHE A 171
TYR A 168
VAL A 126
PHE A 167
 None
COT  A 400 (-4.9A)
COT  A 400 (-4.1A)
COT  A 400 (-4.2A)
 1.34A 3ltwA-1cjwA:
undetectable		 3ltwA-1cjwA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2k CHITINASE 1

(Coccidioides
immitis) 		PF00704
(Glyco_hydro_18) 		4 PHE A 163
TYR A  69
VAL A 105
THR A  89
 None
 1.36A 3ltwA-1d2kA:
undetectable		 3ltwA-1d2kA:
21.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e2t N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Salmonella
enterica) 		PF00797
(Acetyltransf_2) 		6 PHE A  38
TYR A  68
CYH A  69
VAL A  94
THR A 106
PHE A 199
 None
 0.63A 3ltwA-1e2tA:
37.3		 3ltwA-1e2tA:
36.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h1y D-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE

(Oryza sativa) 		PF00834
(Ribul_P_3_epim) 		4 PHE A  90
TYR A  78
VAL A  96
THR A  73
 None
 1.27A 3ltwA-1h1yA:
undetectable		 3ltwA-1h1yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7w DIHYDROPYRIMIDINE
DEHYDROGENASE

(Sus scrofa) 		PF01180
(DHO_dh)
PF07992
(Pyr_redox_2)
PF14691
(Fer4_20)
PF14697
(Fer4_21) 		4 PHE A 387
CYH A 385
THR A 349
PHE A 345
 None
 1.37A 3ltwA-1h7wA:
undetectable		 3ltwA-1h7wA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ib1 SEROTONIN
N-ACETYLTRANSFERASE

(Ovis aries) 		PF00583
(Acetyltransf_1) 		4 PHE E 171
TYR E 168
VAL E 126
PHE E 167
 None
COT  E 401 (-4.8A)
COT  E 401 (-3.8A)
COT  E 401 (-3.6A)
 1.29A 3ltwA-1ib1E:
undetectable		 3ltwA-1ib1E:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lyw CATHEPSIN D

(Homo sapiens) 		PF00026
(Asp) 		4 PHE B 325
TYR B 283
VAL B 208
PHE B 342
 None
 1.01A 3ltwA-1lywB:
undetectable		 3ltwA-1lywB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mda AMICYANIN

(Paracoccus
denitrificans) 		PF00127
(Copper-bind) 		4 PHE A  57
TYR A  88
VAL A  23
PHE A  82
 None
 1.35A 3ltwA-1mdaA:
undetectable		 3ltwA-1mdaA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 PHE A 353
VAL A 274
THR A 283
PHE A 302
 None
 1.34A 3ltwA-1mwoA:
undetectable		 3ltwA-1mwoA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrj SIGNAL RECOGNITION
PARTICLE RECEPTOR
ALPHA SUBUNIT
HOMOLOG

(Saccharomyces
cerevisiae) 		PF09201
(SRX) 		4 PHE A 151
VAL A  89
THR A 105
PHE A 155
 None
 1.17A 3ltwA-1nrjA:
undetectable		 3ltwA-1nrjA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pfx FACTOR IXA

(Sus scrofa) 		PF00008
(EGF)
PF00089
(Trypsin)
PF00594
(Gla)
PF14670
(FXa_inhibition) 		4 PHE C 130
TYR C 128
VAL C 235
PHE L  98
 None
 1.36A 3ltwA-1pfxC:
undetectable		 3ltwA-1pfxC:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1q SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
A

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		4 PHE A 175
TYR A 282
VAL A 137
PHE A 278
 None
 1.33A 3ltwA-1q1qA:
undetectable		 3ltwA-1q1qA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q20 SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
B

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		4 PHE A 190
TYR A 297
VAL A 152
PHE A 293
 None
 1.34A 3ltwA-1q20A:
undetectable		 3ltwA-1q20A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1w STRUCTURAL
MAINTENANCE OF
CHROMOSOME 1

(Saccharomyces
cerevisiae) 		PF02463
(SMC_N) 		4 PHE A1185
TYR A1174
VAL A1159
PHE A1143
 None
 1.34A 3ltwA-1w1wA:
undetectable		 3ltwA-1w1wA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1w4t ARYLAMINE
N-ACETYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00797
(Acetyltransf_2) 		5 PHE A  42
TYR A  72
CYH A  73
VAL A  98
PHE A 206
 None
 0.36A 3ltwA-1w4tA:
35.5		 3ltwA-1w4tA:
33.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1w6f ARYLAMINE
N-ACETYLTRANSFERASE

(Mycolicibacterium
smegmatis) 		PF00797
(Acetyltransf_2) 		6 PHE A  38
TYR A  69
CYH A  70
VAL A  95
THR A 109
PHE A 204
 ISZ  A1276 (-4.4A)
ISZ  A1276 (-3.8A)
ISZ  A1276 (-2.4A)
ISZ  A1276 (-4.5A)
None
ISZ  A1276 (-4.4A)
 0.38A 3ltwA-1w6fA:
43.4		 3ltwA-1w6fA:
61.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdv SON OF SEVENLESS
PROTEIN HOMOLOG 1

(Homo sapiens) 		PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		4 PHE A 634
TYR A 631
CYH A 635
PHE A 627
 None
 0.91A 3ltwA-1xdvA:
2.1		 3ltwA-1xdvA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xpg 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 PHE A  66
TYR A 112
THR A 152
PHE A 105
 None
 1.35A 3ltwA-1xpgA:
undetectable		 3ltwA-1xpgA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvp 60-KDA SS-A/RO
RIBONUCLEOPROTEIN

(Xenopus laevis) 		PF05731
(TROVE) 		4 PHE A 361
TYR A 358
VAL A 395
PHE A 357
 None
 1.38A 3ltwA-1yvpA:
undetectable		 3ltwA-1yvpA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1x PHYTANOYL-COA
DIOXYGENASE

(Homo sapiens) 		PF05721
(PhyH) 		4 PHE A 124
TYR A 133
CYH A 280
VAL A 331
 None
 1.38A 3ltwA-2a1xA:
undetectable		 3ltwA-2a1xA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b71 CYCLOPHILIN-LIKE
PROTEIN

(Plasmodium
yoelii) 		PF00160
(Pro_isomerase) 		4 TYR A  75
CYH A  70
VAL A  52
PHE A 139
 None
 1.28A 3ltwA-2b71A:
undetectable		 3ltwA-2b71A:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bsz ARYLAMINE
N-ACETYLTRANSFERASE
1

(Mesorhizobium
loti) 		PF00797
(Acetyltransf_2) 		5 PHE A  42
TYR A  72
CYH A  73
VAL A  98
PHE A 204
 None
 0.42A 3ltwA-2bszA:
38.8		 3ltwA-2bszA:
43.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g02 NISIN BIOSYNTHESIS
PROTEIN NISC

(Lactococcus
lactis) 		PF05147
(LANC_like) 		4 TYR A 296
CYH A 219
VAL A 142
PHE A 408
 None
 1.10A 3ltwA-2g02A:
undetectable		 3ltwA-2g02A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g29 NITRATE TRANSPORT
PROTEIN NRTA

(Synechocystis
sp.) 		PF13379
(NMT1_2) 		4 PHE A 342
TYR A 333
THR A 259
PHE A 335
 None
 1.38A 3ltwA-2g29A:
undetectable		 3ltwA-2g29A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ija ARYLAMINE
N-ACETYLTRANSFERASE
1

(Homo sapiens) 		PF00797
(Acetyltransf_2) 		4 PHE A  37
CYH A  68
VAL A  93
PHE A 217
 None
ACM  A 301 (-1.7A)
None
ACM  A 301 (-4.2A)
 0.70A 3ltwA-2ijaA:
32.5		 3ltwA-2ijaA:
29.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ld7 HISTONE DEACETYLASE
COMPLEX SUBUNIT
SAP30
PAIRED AMPHIPATHIC
HELIX PROTEIN SIN3A

(Mus musculus) 		PF02671
(PAH)
PF13867
(SAP30_Sin3_bdg) 		4 PHE A 200
VAL B 461
THR B 463
PHE B 522
 None
 1.11A 3ltwA-2ld7A:
undetectable		 3ltwA-2ld7A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m4l PROTEIN BT_0846

(Bacteroides
thetaiotaomicron) 		no annotation 4 PHE A  51
TYR A  53
VAL A  86
PHE A  29
 None
 0.88A 3ltwA-2m4lA:
undetectable		 3ltwA-2m4lA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n93 FATTY ACID-BINDING
PROTEIN

(Luciola cerata) 		PF14651
(Lipocalin_7) 		4 PHE A 112
TYR A 105
VAL A  63
THR A  82
 None
 1.29A 3ltwA-2n93A:
undetectable		 3ltwA-2n93A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6z UROPORPHYRINOGEN
DECARBOXYLASE

(Homo sapiens) 		PF01208
(URO-D) 		4 PHE A  84
CYH A  65
VAL A  89
PHE A  55
 None
 1.35A 3ltwA-2q6zA:
undetectable		 3ltwA-2q6zA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v2k FERREDOXIN

(Mycolicibacterium
smegmatis) 		PF00037
(Fer4) 		4 TYR A  33
VAL A  87
THR A  90
PHE A  75
 None
 1.14A 3ltwA-2v2kA:
undetectable		 3ltwA-2v2kA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdt LEVANSUCRASE

(Bacillus
subtilis) 		PF02435
(Glyco_hydro_68) 		4 PHE A 347
TYR A 354
THR A 456
PHE A 356
 None
 1.33A 3ltwA-2vdtA:
undetectable		 3ltwA-2vdtA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzr POLYPROTEIN

(Foot-and-mouth
disease virus) 		PF00073
(Rhv) 		4 PHE 3 212
TYR 3 101
VAL 3 204
PHE 3  81
 None
 1.06A 3ltwA-2wzr3:
undetectable		 3ltwA-2wzr3:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II CORE
LIGHT HARVESTING
PROTEIN

(Thermosynechococcus
vulcanus) 		PF00421
(PSII) 		4 PHE B  61
VAL B 252
THR B 263
PHE B  65
 CLA  B1015 ( 3.4A)
CLA  B1012 (-4.5A)
None
CLA  B1012 ( 3.2A)
 1.39A 3ltwA-3a0hB:
undetectable		 3ltwA-3a0hB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak5 HEMOGLOBIN-BINDING
PROTEASE HBP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 PHE A 102
VAL A 189
THR A 221
PHE A  67
 None
 1.12A 3ltwA-3ak5A:
undetectable		 3ltwA-3ak5A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkp CYCLOPHILIN

(Toxoplasma
gondii) 		PF00160
(Pro_isomerase) 		4 TYR A  58
CYH A  53
VAL A  35
PHE A 138
 None
 1.32A 3ltwA-3bkpA:
undetectable		 3ltwA-3bkpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ch0 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Cytophaga
hutchinsonii) 		PF03009
(GDPD) 		4 PHE A 170
TYR A 132
VAL A  51
PHE A  41
 None
 1.32A 3ltwA-3ch0A:
undetectable		 3ltwA-3ch0A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxp GLUCOSAMINE
6-PHOSPHATE
N-ACETYLTRANSFERASE

(Homo sapiens) 		PF00583
(Acetyltransf_1) 		4 PHE A 168
TYR A 165
VAL A 124
PHE A 164
 None
 1.33A 3ltwA-3cxpA:
undetectable		 3ltwA-3cxpA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica) 		PF00797
(Acetyltransf_2) 		6 PHE A  51
TYR A  81
CYH A  82
VAL A 107
THR A 118
PHE A 218
 None
 0.66A 3ltwA-3d9wA:
34.8		 3ltwA-3d9wA:
35.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxl UNCHARACTERIZED
PROTEIN DSY3957

(Desulfitobacterium
hafniense) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 TYR A 288
VAL A 234
THR A 267
PHE A 314
 None
 1.39A 3ltwA-3hxlA:
undetectable		 3ltwA-3hxlA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ii7 KELCH-LIKE PROTEIN 7

(Homo sapiens) 		PF01344
(Kelch_1) 		4 TYR A 385
CYH A 378
VAL A 434
PHE A 400
 None
 1.31A 3ltwA-3ii7A:
undetectable		 3ltwA-3ii7A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwg ACETYLTRANSFERASE,
GNAT FAMILY

(Colwellia
psychrerythraea) 		PF00583
(Acetyltransf_1) 		4 TYR A  66
CYH A  55
VAL A  94
PHE A  80
 None
 0.97A 3ltwA-3iwgA:
undetectable		 3ltwA-3iwgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00797
(Acetyltransf_2) 		4 PHE A  38
CYH A  69
VAL A  94
PHE A 216
 COA  A1001 (-4.4A)
COA  A1001 (-2.6A)
COA  A1001 ( 4.7A)
COA  A1001 (-3.7A)
 0.38A 3ltwA-3lnbA:
30.7		 3ltwA-3lnbA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5l BINDING PROTEIN
COMPONENT OF ABC
PHOSPHONATE
TRANSPORTER

(Pseudomonas
aeruginosa) 		PF12974
(Phosphonate-bd) 		4 PHE A 249
TYR A 252
VAL A  62
PHE A  50
 None
 1.28A 3ltwA-3n5lA:
undetectable		 3ltwA-3n5lA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium) 		PF02435
(Glyco_hydro_68) 		5 PHE A 357
TYR A 364
VAL A 459
THR A 466
PHE A 366
 None
 1.40A 3ltwA-3om5A:
undetectable		 3ltwA-3om5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxh RV0577 PROTEIN

(Mycobacterium
tuberculosis) 		PF00903
(Glyoxalase) 		4 TYR A 161
VAL A 100
THR A 117
PHE A 160
 None
 1.23A 3ltwA-3oxhA:
undetectable		 3ltwA-3oxhA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgv ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 PHE A 353
VAL A 274
THR A 283
PHE A 302
 None
 1.38A 3ltwA-3qgvA:
undetectable		 3ltwA-3qgvA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ryl PROTEIN VPA1370

(Vibrio
parahaemolyticus) 		no annotation 4 PHE A 435
TYR A 432
VAL A 405
PHE A 431
 None
 1.33A 3ltwA-3rylA:
undetectable		 3ltwA-3rylA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ul4 CELLULOSOME-ANCHORIN
G PROTEIN

(Ruminiclostridium
thermocellum) 		PF00963
(Cohesin) 		4 TYR A  71
VAL A  27
THR A 103
PHE A  69
 None
 1.07A 3ltwA-3ul4A:
undetectable		 3ltwA-3ul4A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vk5 MOEO5

(Streptomyces
viridosporus) 		PF01884
(PcrB) 		4 PHE A  43
TYR A  72
VAL A 109
PHE A  98
 None
 1.05A 3ltwA-3vk5A:
undetectable		 3ltwA-3vk5A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 PHE A 565
TYR A 521
CYH A 524
PHE A 470
 None
 1.17A 3ltwA-3wdjA:
undetectable		 3ltwA-3wdjA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgx CHROMOSOME PARTITION
PROTEIN SMC

(Bacillus
subtilis) 		PF02463
(SMC_N) 		4 PHE A1103
VAL A1146
THR A1153
PHE A1131
 None
 1.29A 3ltwA-3zgxA:
undetectable		 3ltwA-3zgxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag9 GLUCOSAMINE-6-PHOSPH
ATE
N-ACETYLTRANSFERASE

(Caenorhabditis
elegans) 		PF00583
(Acetyltransf_1) 		4 PHE A 152
TYR A 149
VAL A 108
PHE A 148
 None
None
COA  A1166 ( 4.8A)
COA  A1166 (-4.0A)
 1.38A 3ltwA-4ag9A:
undetectable		 3ltwA-4ag9A:
20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4bgf ARYLAMINE
N-ACETYLTRANSFERASE
NAT

(Mycobacterium
tuberculosis) 		PF00797
(Acetyltransf_2) 		6 PHE A  38
TYR A  69
CYH A  70
VAL A  95
THR A 109
PHE A 204
 None
 0.29A 3ltwA-4bgfA:
44.2		 3ltwA-4bgfA:
74.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  46
VAL A 116
THR A 123
PHE A  97
 None
 1.36A 3ltwA-4bmbA:
undetectable		 3ltwA-4bmbA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buj ANTIVIRAL PROTEIN
SKI8

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 PHE C 362
CYH C 307
THR C 327
PHE C   5
 None
 1.37A 3ltwA-4bujC:
3.3		 3ltwA-4bujC:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmo N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Bacillus cereus) 		PF00797
(Acetyltransf_2) 		4 PHE A  38
CYH A  69
VAL A  94
PHE A 211
 None
 0.47A 3ltwA-4dmoA:
31.1		 3ltwA-4dmoA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgm AMINOPEPTIDASE N
FAMILY PROTEIN

(Idiomarina
loihiensis) 		PF05299
(Peptidase_M61)
PF13180
(PDZ_2) 		4 TYR A 312
VAL A 404
THR A 400
PHE A 313
 None
 1.34A 3ltwA-4fgmA:
undetectable		 3ltwA-4fgmA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqz GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  46
VAL A 116
THR A 123
PHE A  97
 None
 1.33A 3ltwA-4fqzA:
undetectable		 3ltwA-4fqzA:
22.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4guz PROBABLE ARYLAMINE
N-ACETYL TRANSFERASE

(Mycobacteroides
abscessus) 		PF00797
(Acetyltransf_2) 		5 TYR A  72
CYH A  73
VAL A  98
THR A 109
PHE A 210
 None
 0.75A 3ltwA-4guzA:
33.7		 3ltwA-4guzA:
34.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i84 HEME/HEMOPEXIN-BINDI
NG PROTEIN

(Haemophilus
influenzae) 		PF05860
(Haemagg_act) 		4 PHE A 122
TYR A  81
VAL A  11
THR A  31
 None
 1.29A 3ltwA-4i84A:
undetectable		 3ltwA-4i84A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 PHE A 388
TYR A 395
THR A 397
PHE A 427
 None
 1.35A 3ltwA-4iugA:
undetectable		 3ltwA-4iugA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF

(Pseudomonas
putida) 		PF00171
(Aldedh) 		4 PHE A 466
TYR A 161
VAL A 146
PHE A 457
 None
 1.08A 3ltwA-4jz6A:
undetectable		 3ltwA-4jz6A:
19.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nv7 ARYLAMINE
N-ACETYLTRANSFERASE

(Mesorhizobium
japonicum) 		PF00797
(Acetyltransf_2) 		4 TYR A  72
CYH A  73
VAL A  98
PHE A 204
 COA  A 301 ( 4.4A)
COA  A 301 (-2.5A)
COA  A 301 ( 4.9A)
COA  A 301 ( 4.8A)
 0.34A 3ltwA-4nv7A:
39.3		 3ltwA-4nv7A:
38.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5k RAS PEPTIDE,HLA
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DP BETA 1
CHAIN

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 PHE B  35
TYR B  28
THR B -16
PHE B   9
 None
 1.12A 3ltwA-4p5kB:
undetectable		 3ltwA-4p5kB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptf DNA POLYMERASE
EPSILON CATALYTIC
SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 PHE A 121
TYR A 265
VAL A 117
PHE A 272
 None
 1.16A 3ltwA-4ptfA:
undetectable		 3ltwA-4ptfA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5w MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 PHE A2121
CYH A2087
VAL A2117
PHE A1998
 EPE  A2201 (-4.4A)
None
None
EPE  A2201 (-3.3A)
 1.27A 3ltwA-4q5wA:
undetectable		 3ltwA-4q5wA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEME/HEMOPEXIN-BINDI
NG PROTEIN

(Haemophilus
influenzae) 		PF05860
(Haemagg_act) 		4 PHE A 124
TYR A  83
VAL A  13
THR A  33
 None
 1.29A 3ltwA-4rt6A:
undetectable		 3ltwA-4rt6A:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry8 PERIPLASMIC BINDING
PROTEIN

(Pseudothermotoga
lettingae) 		PF13407
(Peripla_BP_4) 		4 PHE A  48
TYR A  52
VAL A 300
PHE A 121
 SR1  A 401 (-3.6A)
None
None
None
 1.03A 3ltwA-4ry8A:
undetectable		 3ltwA-4ry8A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wri OKADAIC ACID BINDING
PROTEIN 2-ALPHA

(Halichondria
okadai) 		no annotation 4 TYR A  87
CYH A  70
VAL A  36
PHE A  19
 None
 0.87A 3ltwA-4wriA:
undetectable		 3ltwA-4wriA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xt1 FRACTALKINE
G-PROTEIN COUPLED
RECEPTOR HOMOLOG
US28

(Cytomegalovirus;
Homo sapiens) 		PF00001
(7tm_1)
PF00048
(IL8) 		4 PHE A  82
VAL B   5
THR A  36
PHE A 281
 None
 1.17A 3ltwA-4xt1A:
undetectable		 3ltwA-4xt1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9n AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN

(Brucella ovis) 		PF00497
(SBP_bac_3) 		4 PHE A 144
VAL A 130
THR A 136
PHE A 107
 None
None
GSH  A 401 ( 4.8A)
None
 1.28A 3ltwA-4z9nA:
undetectable		 3ltwA-4z9nA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzh NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-1

(Homo sapiens) 		PF02146
(SIR2) 		4 PHE A 652
TYR A 642
VAL A 476
THR A 242
 None
 1.24A 3ltwA-4zzhA:
undetectable		 3ltwA-4zzhA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c7m E3 UBIQUITIN-PROTEIN
LIGASE ITCHY HOMOLOG

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 757
VAL A 604
THR A 657
PHE A 659
 None
 1.35A 3ltwA-5c7mA:
undetectable		 3ltwA-5c7mA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4c PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		no annotation 4 PHE A  73
VAL A  32
THR A  22
PHE A  17
 None
 1.20A 3ltwA-5f4cA:
undetectable		 3ltwA-5f4cA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzg GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  46
VAL A 116
THR A 123
PHE A  97
 None
 1.36A 3ltwA-5gzgA:
undetectable		 3ltwA-5gzgA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A

(Aspergillus
niger) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 PHE A 388
TYR A 395
THR A 397
PHE A 427
 None
 1.33A 3ltwA-5ihrA:
undetectable		 3ltwA-5ihrA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 PHE A 139
TYR A 137
VAL A 162
PHE A 204
 None
 1.31A 3ltwA-5ipwA:
undetectable		 3ltwA-5ipwA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpe SERINE/THREONINE-PRO
TEIN PHOSPHATASE

(Candida
albicans) 		PF00149
(Metallophos)
PF16891
(STPPase_N) 		4 PHE A 283
TYR A 275
VAL A 230
PHE A 241
 None
 1.25A 3ltwA-5jpeA:
undetectable		 3ltwA-5jpeA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpe SERINE/THREONINE-PRO
TEIN PHOSPHATASE

(Candida
albicans) 		PF00149
(Metallophos)
PF16891
(STPPase_N) 		4 PHE A 283
VAL A 230
THR A 268
PHE A 241
 None
 1.37A 3ltwA-5jpeA:
undetectable		 3ltwA-5jpeA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kn8 ADENINE DNA
GLYCOSYLASE

(Geobacillus
stearothermophilus) 		PF00633
(HHH)
PF00730
(HhH-GPD) 		4 PHE A   8
TYR A 213
VAL A 150
PHE A  13
 None
 1.27A 3ltwA-5kn8A:
undetectable		 3ltwA-5kn8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m28 MALE1

(Lactobacillus
casei) 		PF13416
(SBP_bac_8) 		4 PHE A 267
VAL A 190
THR A 188
PHE A 352
 None
 1.03A 3ltwA-5m28A:
undetectable		 3ltwA-5m28A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5x DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA135

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF06883
(RNA_pol_Rpa2_4) 		4 PHE B 986
TYR B 995
VAL B 752
PHE B 996
 None
 1.27A 3ltwA-5m5xB:
undetectable		 3ltwA-5m5xB:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mc5 XAA-PRO DIPEPTIDASE

(Homo sapiens) 		no annotation 4 PHE A 284
CYH A 283
THR A  78
PHE A  23
 None
 1.22A 3ltwA-5mc5A:
undetectable		 3ltwA-5mc5A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ng6 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Francisella
tularensis) 		no annotation 4 PHE A 786
TYR A 784
THR A 618
PHE A 600
 None
 1.31A 3ltwA-5ng6A:
undetectable		 3ltwA-5ng6A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oki DNA POLYMERASE
EPSILON CATALYTIC
SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A 121
TYR A 265
VAL A 117
PHE A 272
 None
 1.24A 3ltwA-5okiA:
undetectable		 3ltwA-5okiA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63) 		PF01600
(Corona_S1)
PF01601
(Corona_S2) 		4 PHE A 412
TYR A 298
VAL A 373
PHE A 402
 None
 1.26A 3ltwA-5szsA:
undetectable		 3ltwA-5szsA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE

(Zymomonas
mobilis) 		no annotation 4 TYR A 354
VAL A  51
THR A 285
PHE A  42
 None
 1.37A 3ltwA-5utiA:
undetectable		 3ltwA-5utiA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v9p LYSINE-SPECIFIC
DEMETHYLASE 5A

(Homo sapiens) 		PF00628
(PHD)
PF01388
(ARID)
PF02373
(JmjC)
PF02375
(JmjN)
PF02928
(zf-C5HC2)
PF08429
(PLU-1) 		4 PHE A  70
TYR A 361
VAL A 407
PHE A 366
 None
 1.38A 3ltwA-5v9pA:
undetectable		 3ltwA-5v9pA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vol PUTATIVE ESTERASE

(Bacteroides
intestinalis) 		PF00756
(Esterase) 		4 PHE A 169
TYR A 161
VAL A  98
PHE A 125
 None
 1.15A 3ltwA-5volA:
undetectable		 3ltwA-5volA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ww1 PULULLANASE

(Paenibacillus
barengoltzii) 		no annotation 4 PHE A 532
TYR A 488
CYH A 491
PHE A 430
 None
 1.14A 3ltwA-5ww1A:
undetectable		 3ltwA-5ww1A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yb7 L-AMINO ACID
OXIDASE/MONOOXYGENAS
E

(Pseudomonas sp.
AIU 813) 		no annotation 4 PHE A 402
TYR A 400
CYH A 413
PHE A 124
 None
 1.23A 3ltwA-5yb7A:
undetectable		 3ltwA-5yb7A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Caldanaerobacter
subterraneus) 		no annotation 4 TYR A 363
VAL A 177
THR A 173
PHE A 282
 None
None
SAM  A 601 (-3.2A)
None
 1.21A 3ltwA-5ybbA:
undetectable		 3ltwA-5ybbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z24 PILUS ASSEMBLY
PROTEIN

(Lactobacillus
rhamnosus) 		no annotation 4 PHE A 143
TYR A 141
VAL A 164
PHE A  41
 None
 1.19A 3ltwA-5z24A:
undetectable		 3ltwA-5z24A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6beg SCAFFOLD PROTEIN D13

(Vaccinia virus) 		no annotation 4 PHE A 433
VAL A 521
THR A 266
PHE A 270
 FMT  A 601 (-4.7A)
None
None
None
 1.39A 3ltwA-6begA:
undetectable		 3ltwA-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g47 FIBER-1

(Human
mastadenovirus
G) 		no annotation 4 PHE A 329
TYR A 309
VAL A 232
THR A 355
 None
 1.32A 3ltwA-6g47A:
undetectable		 3ltwA-6g47A:
11.79