SIMILAR PATTERNS OF AMINO ACIDS FOR 3LSF_E_PZIE802
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 3 | ASP A2809ASN A2811SER A2676 | None | 0.89A | 3lsfB-1js8A:0.03lsfE-1js8A:undetectable | 3lsfB-1js8A:21.573lsfE-1js8A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jye | LACTOSE OPERONREPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 3 | ASP A 149ASN A 125SER A 191 | None | 0.92A | 3lsfB-1jyeA:2.43lsfE-1jyeA:3.1 | 3lsfB-1jyeA:22.563lsfE-1jyeA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jye | LACTOSE OPERONREPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 3 | ASP A 149ASN A 125SER A 193 | NoneNoneGOL A 350 ( 4.3A) | 0.99A | 3lsfB-1jyeA:2.43lsfE-1jyeA:3.1 | 3lsfB-1jyeA:22.563lsfE-1jyeA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpb | LIPASE (Homo sapiens) |
PF00151(Lipase)PF01477(PLAT) | 3 | ASP B 272ASN B 92SER B 333 | NoneNoneBOG B 452 (-3.5A) | 0.99A | 3lsfB-1lpbB:0.03lsfE-1lpbB:0.0 | 3lsfB-1lpbB:18.933lsfE-1lpbB:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m58 | RC-RNASE2RIBONUCLEASE (Ranacatesbeiana) |
PF00074(RnaseA) | 3 | ASP A 68ASN A 70SER A 83 | None | 1.01A | 3lsfB-1m58A:undetectable3lsfE-1m58A:undetectable | 3lsfB-1m58A:17.483lsfE-1m58A:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nw1 | CHOLINE KINASE (49.2KD) (Caenorhabditiselegans) |
PF01633(Choline_kinase) | 3 | ASP A 255ASN A 316SER A 86 | None | 0.81A | 3lsfB-1nw1A:0.03lsfE-1nw1A:0.0 | 3lsfB-1nw1A:19.363lsfE-1nw1A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o12 | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Thermotogamaritima) |
PF01979(Amidohydro_1) | 3 | ASP A 229ASN A 301SER A 291 | None | 0.92A | 3lsfB-1o12A:0.03lsfE-1o12A:undetectable | 3lsfB-1o12A:22.793lsfE-1o12A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pek | PROTEINASE K (Parengyodontiumalbum) |
PF00082(Peptidase_S8) | 3 | ASP E 165ASN E 168SER E 197 | None | 0.89A | 3lsfB-1pekE:0.43lsfE-1pekE:undetectable | 3lsfB-1pekE:21.143lsfE-1pekE:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgu | ACTIN INTERACTINGPROTEIN 1 (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | ASP A 318ASN A 299SER A 336 | None | 1.01A | 3lsfB-1pguA:undetectable3lsfE-1pguA:undetectable | 3lsfB-1pguA:18.203lsfE-1pguA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd6 | PROTEIN (OUTERMEMBRANEPHOSPHOLIPASE(OMPLA)) (Escherichiacoli) |
PF02253(PLA1) | 3 | ASP C 267ASN C 266SER C 209 | None | 0.99A | 3lsfB-1qd6C:undetectable3lsfE-1qd6C:undetectable | 3lsfB-1qd6C:22.733lsfE-1qd6C:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1td0 | HEAD DECORATIONPROTEIN (Escherichiavirus Lambda) |
PF02924(HDPD) | 3 | ASP A 19ASN A 18SER A 109 | None | 1.00A | 3lsfB-1td0A:undetectable3lsfE-1td0A:undetectable | 3lsfB-1td0A:20.483lsfE-1td0A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlf | LAC REPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 3 | ASP A 149ASN A 125SER A 191 | IPT A 998 (-3.2A)IPT A 998 ( 4.7A)IPT A 998 ( 4.6A) | 0.89A | 3lsfB-1tlfA:undetectable3lsfE-1tlfA:3.5 | 3lsfB-1tlfA:23.653lsfE-1tlfA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1toc | ORNITHODORIN (Ornithodorosmoubata) |
no annotation | 3 | ASP R 16ASN R 14SER R 37 | None | 0.64A | 3lsfB-1tocR:undetectable3lsfE-1tocR:undetectable | 3lsfB-1tocR:16.063lsfE-1tocR:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uag | UDP-N-ACETYLMURAMOYL-L-ALANINE/:D-GLUTAMATE LIGASE (Escherichiacoli) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 3 | ASP A 317ASN A 316SER A 325 | NoneNoneSO4 A 964 ( 4.9A) | 0.82A | 3lsfB-1uagA:undetectable3lsfE-1uagA:undetectable | 3lsfB-1uagA:21.363lsfE-1uagA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uli | BIPHENYL DIOXYGENASELARGE SUBUNIT (Rhodococcusjostii) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 3 | ASP A 377ASN A 381SER A 232 | None | 1.02A | 3lsfB-1uliA:undetectable3lsfE-1uliA:undetectable | 3lsfB-1uliA:19.393lsfE-1uliA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wop | AMINOMETHYLTRANSFERASE (Thermotogamaritima) |
PF01571(GCV_T)PF08669(GCV_T_C) | 3 | ASP A 72ASN A 261SER A 75 | None | 1.02A | 3lsfB-1wopA:undetectable3lsfE-1wopA:undetectable | 3lsfB-1wopA:24.933lsfE-1wopA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfu | CALMODULIN-SENSITIVEADENYLATE CYCLASE (Bacillusanthracis) |
PF03497(Anthrax_toxA)PF07737(ATLF) | 3 | ASP A 406ASN A 451SER A 341 | None | 0.99A | 3lsfB-1xfuA:undetectable3lsfE-1xfuA:undetectable | 3lsfB-1xfuA:15.783lsfE-1xfuA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yd9 | CORE HISTONEMACRO-H2A.1 (Rattusnorvegicus) |
PF01661(Macro) | 3 | ASP A 191ASN A 193SER A 156 | None | 0.68A | 3lsfB-1yd9A:undetectable3lsfE-1yd9A:undetectable | 3lsfB-1yd9A:20.523lsfE-1yd9A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zy9 | ALPHA-GALACTOSIDASE (Thermotogamaritima) |
PF02065(Melibiase) | 3 | ASP A 494ASN A 516SER A 492 | None | 0.99A | 3lsfB-1zy9A:undetectable3lsfE-1zy9A:undetectable | 3lsfB-1zy9A:20.223lsfE-1zy9A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2atm | HYALURONOGLUCOSAMINIDASE (Vespulavulgaris) |
PF01630(Glyco_hydro_56) | 3 | ASP A 45ASN A 97SER A 38 | None | 1.02A | 3lsfB-2atmA:undetectable3lsfE-2atmA:undetectable | 3lsfB-2atmA:21.083lsfE-2atmA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2au1 | IGG-DEGRADINGPROTEASE (Streptococcuspyogenes) |
PF09028(Mac-1) | 3 | ASP A 81ASN A 101SER A 287 | None | 1.02A | 3lsfB-2au1A:undetectable3lsfE-2au1A:undetectable | 3lsfB-2au1A:21.263lsfE-2au1A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4k | PHOSPHORIBOSYLPYROPHOSPHATESYNTHETASE-ASSOCIATED PROTEIN 1 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 3 | ASP A 134ASN A 150SER A 154 | None | 0.96A | 3lsfB-2c4kA:undetectable3lsfE-2c4kA:undetectable | 3lsfB-2c4kA:21.983lsfE-2c4kA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1c | ISOCITRATEDEHYDROGENASE (Thermusthermophilus) |
PF00180(Iso_dh) | 3 | ASP A 442ASN A 399SER A 154 | None | 0.92A | 3lsfB-2d1cA:undetectable3lsfE-2d1cA:undetectable | 3lsfB-2d1cA:19.683lsfE-2d1cA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3x | COAGULATION FACTORX-ACTIVATING ENZYMEHEAVY CHAIN (Daboiasiamensis) |
PF00200(Disintegrin)PF01421(Reprolysin)PF08516(ADAM_CR) | 3 | ASP A 66ASN A 69SER A 22 | NoneNAG A 900 ( 2.0A)None | 0.92A | 3lsfB-2e3xA:undetectable3lsfE-2e3xA:undetectable | 3lsfB-2e3xA:18.793lsfE-2e3xA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 3 | ASP A 381ASN A 382SER A 388 | None | 0.99A | 3lsfB-2exaA:undetectable3lsfE-2exaA:undetectable | 3lsfB-2exaA:20.483lsfE-2exaA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3o | PYRUVATEFORMATE-LYASE 2 (Archaeoglobusfulgidus) |
PF01228(Gly_radical)PF02901(PFL-like) | 3 | ASP A 666ASN A 594SER A 773 | None | 0.82A | 3lsfB-2f3oA:undetectable3lsfE-2f3oA:undetectable | 3lsfB-2f3oA:17.653lsfE-2f3oA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsb | RASGTPASE-ACTIVATINGPROTEIN 1 (Homo sapiens) |
PF00017(SH2) | 3 | ASP A 47ASN A 48SER A 24 | None | 0.95A | 3lsfB-2gsbA:undetectable3lsfE-2gsbA:undetectable | 3lsfB-2gsbA:18.523lsfE-2gsbA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj9 | AUTOINDUCER2-BINDINGPERIPLASMIC PROTEINLUXP (Vibrio harveyi) |
PF13407(Peripla_BP_4) | 3 | ASP A 136ASN A 159SER A 207 | NoneAI2 A 501 (-3.3A)None | 0.99A | 3lsfB-2hj9A:3.23lsfE-2hj9A:2.6 | 3lsfB-2hj9A:20.113lsfE-2hj9A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p50 | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 3 | ASP A 248ASN A 319SER A 309 | None | 0.88A | 3lsfB-2p50A:undetectable3lsfE-2p50A:undetectable | 3lsfB-2p50A:21.143lsfE-2p50A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfo | NUCLEOPORIN NIC96 (Saccharomycescerevisiae) |
PF04097(Nic96) | 3 | ASP A 419ASN A 395SER A 421 | None | 0.86A | 3lsfB-2rfoA:undetectable3lsfE-2rfoA:undetectable | 3lsfB-2rfoA:17.213lsfE-2rfoA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x98 | ALKALINE PHOSPHATASE (Halobacteriumsalinarum) |
PF00245(Alk_phosphatase) | 3 | ASP A 261ASN A 268SER A 375 | None | 0.84A | 3lsfB-2x98A:undetectable3lsfE-2x98A:undetectable | 3lsfB-2x98A:19.033lsfE-2x98A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckm | YRAM (HI1655) (Haemophilusinfluenzae) |
PF04348(LppC) | 3 | ASP A 559ASN A 371SER A 549 | None | 1.00A | 3lsfB-3ckmA:undetectable3lsfE-3ckmA:undetectable | 3lsfB-3ckmA:19.943lsfE-3ckmA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clk | TRANSCRIPTIONREGULATOR (Lactobacillusplantarum) |
PF13377(Peripla_BP_3) | 3 | ASP A 247ASN A 74SER A 288 | None | 0.97A | 3lsfB-3clkA:undetectable3lsfE-3clkA:2.7 | 3lsfB-3clkA:22.873lsfE-3clkA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6i | MONOTHIOLGLUTAREDOXIN-3 (Saccharomycescerevisiae) |
PF00085(Thioredoxin) | 3 | ASP A 97ASN A 42SER A 67 | None | 0.99A | 3lsfB-3d6iA:undetectable3lsfE-3d6iA:undetectable | 3lsfB-3d6iA:17.063lsfE-3d6iA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d7r | ESTERASE (Staphylococcusaureus) |
PF07859(Abhydrolase_3) | 3 | ASP A 184ASN A 230SER A 188 | None | 0.86A | 3lsfB-3d7rA:undetectable3lsfE-3d7rA:undetectable | 3lsfB-3d7rA:18.603lsfE-3d7rA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egj | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Vibrio cholerae) |
PF01979(Amidohydro_1) | 3 | ASP A 245ASN A 316SER A 306 | None | 0.83A | 3lsfB-3egjA:undetectable3lsfE-3egjA:undetectable | 3lsfB-3egjA:23.513lsfE-3egjA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw8 | RETICULINE OXIDASE (Eschscholziacalifornica) |
PF01565(FAD_binding_4)PF08031(BBE) | 3 | ASP A 121ASN A 124SER A 57 | NoneNAG A 521 (-2.9A)None | 0.91A | 3lsfB-3fw8A:undetectable3lsfE-3fw8A:undetectable | 3lsfB-3fw8A:21.413lsfE-3fw8A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 3 | ASP A 487ASN A 484SER A 86 | None | 0.99A | 3lsfB-3h7lA:undetectable3lsfE-3h7lA:undetectable | 3lsfB-3h7lA:16.843lsfE-3h7lA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETACARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica;Moorellathermoacetica) |
PF03063(Prismane)PF03598(CdhC) | 3 | ASP A 226ASN A 225SER M 34 | None | 0.94A | 3lsfB-3i04A:undetectable3lsfE-3i04A:undetectable | 3lsfB-3i04A:17.233lsfE-3i04A:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i12 | D-ALANINE-D-ALANINELIGASE A (Salmonellaenterica) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 3 | ASP A 113ASN A 188SER A 115 | None | 0.91A | 3lsfB-3i12A:undetectable3lsfE-3i12A:undetectable | 3lsfB-3i12A:21.993lsfE-3i12A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i12 | D-ALANINE-D-ALANINELIGASE A (Salmonellaenterica) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 3 | ASP A 263ASN A 264SER A 326 | None | 0.94A | 3lsfB-3i12A:undetectable3lsfE-3i12A:undetectable | 3lsfB-3i12A:21.993lsfE-3i12A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3t | UBIQUITINCARBOXYL-TERMINALHYDROLASE 21 (Homo sapiens) |
PF00443(UCH) | 3 | ASP A 352ASN A 356SER A 494 | None | 0.81A | 3lsfB-3i3tA:undetectable3lsfE-3i3tA:undetectable | 3lsfB-3i3tA:21.013lsfE-3i3tA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 4 (Thermusthermophilus) |
PF00346(Complex1_49kDa) | 3 | ASP 4 401ASN 4 377SER 4 128 | None | 0.94A | 3lsfB-3i9v4:undetectable3lsfE-3i9v4:undetectable | 3lsfB-3i9v4:20.623lsfE-3i9v4:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9e | VP5 (Bluetonguevirus) |
PF00901(Orbi_VP5) | 3 | ASP D 472ASN D 476SER D 305 | None | 0.37A | 3lsfB-3j9eD:undetectable3lsfE-3j9eD:undetectable | 3lsfB-3j9eD:19.083lsfE-3j9eD:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42PRE-MRNA-SPLICINGFACTOR CWF14 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV)PF01423(LSM) | 3 | ASP A 81ASN e 87SER A 509 | None G C 75 ( 4.7A)None | 0.92A | 3lsfB-3jb9A:undetectable3lsfE-3jb9A:undetectable | 3lsfB-3jb9A:7.593lsfE-3jb9A:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jwo | HIV-1 GP120 ENVELOPEGLYCOPROTEIN (Homo sapiens) |
PF00516(GP120) | 3 | ASP A 457ASN A 462SER A 365 | None | 0.85A | 3lsfB-3jwoA:undetectable3lsfE-3jwoA:undetectable | 3lsfB-3jwoA:20.383lsfE-3jwoA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhx | KETODEOXYGLUCONOKINASE (Shigellaflexneri) |
PF00294(PfkB) | 3 | ASP A 102ASN A 105SER A 210 | None | 0.79A | 3lsfB-3lhxA:undetectable3lsfE-3lhxA:undetectable | 3lsfB-3lhxA:22.333lsfE-3lhxA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mz1 | PUTATIVETRANSCRIPTIONALREGULATOR (Sinorhizobiummeliloti) |
PF03466(LysR_substrate) | 3 | ASP A 123ASN A 218SER A 94 | None | 0.82A | 3lsfB-3mz1A:7.93lsfE-3mz1A:7.7 | 3lsfB-3mz1A:21.543lsfE-3mz1A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6x | PUTATIVEGLUTATHIONYLSPERMIDINE SYNTHASE (Methylobacillusflagellatus) |
PF14403(CP_ATPgrasp_2) | 3 | ASP A 321ASN A 123SER A 349 | None | 0.93A | 3lsfB-3n6xA:undetectable3lsfE-3n6xA:undetectable | 3lsfB-3n6xA:19.673lsfE-3n6xA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3m | BETA SUBUNIT2-HYDROXYACYL-COADEHYDRATASE (Clostridioidesdifficile) |
PF06050(HGD-D) | 3 | ASP B 352ASN B 358SER B 73 | None | 1.02A | 3lsfB-3o3mB:undetectable3lsfE-3o3mB:undetectable | 3lsfB-3o3mB:19.903lsfE-3o3mB:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6p | PEPTIDE ABCTRANSPORTER,PEPTIDE-BINDINGPROTEIN (Enterococcusfaecalis) |
PF00496(SBP_bac_5) | 3 | ASP A 466ASN A 472SER A 492 | None | 0.84A | 3lsfB-3o6pA:undetectable3lsfE-3o6pA:1.4 | 3lsfB-3o6pA:21.373lsfE-3o6pA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojy | COMPLEMENT COMPONENTC8 BETA CHAIN (Homo sapiens) |
PF00057(Ldl_recept_a)PF00090(TSP_1)PF01823(MACPF) | 3 | ASP B 491ASN B 515SER B 232 | None | 0.82A | 3lsfB-3ojyB:undetectable3lsfE-3ojyB:undetectable | 3lsfB-3ojyB:19.723lsfE-3ojyB:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oyo | HEMOPEXIN FOLDPROTEIN CP4 (Vignaunguiculata) |
PF00045(Hemopexin) | 3 | ASP A 65ASN A 7SER A 119 | None CA A 228 (-3.5A)None | 1.01A | 3lsfB-3oyoA:undetectable3lsfE-3oyoA:undetectable | 3lsfB-3oyoA:23.963lsfE-3oyoA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozy | PUTATIVE MANDELATERACEMASE (Bordetellabronchiseptica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ASP A 308ASN A 335SER A 51 | None | 0.96A | 3lsfB-3ozyA:undetectable3lsfE-3ozyA:undetectable | 3lsfB-3ozyA:21.353lsfE-3ozyA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5p | TAXADIENE SYNTHASE (Taxusbrevifolia) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | ASP A 141ASN A 195SER A 313 | None | 0.95A | 3lsfB-3p5pA:undetectable3lsfE-3p5pA:undetectable | 3lsfB-3p5pA:15.023lsfE-3p5pA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r11 | ENZYME OF ENOLASESUPERFAMILY (Francisellaphilomiragia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ASP A 321ASN A 267SER A 137 | None | 0.96A | 3lsfB-3r11A:undetectable3lsfE-3r11A:undetectable | 3lsfB-3r11A:20.683lsfE-3r11A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdq | ALPHA-BISABOLENESYNTHASE (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | ASP A 472ASN A 487SER A 124 | None | 0.98A | 3lsfB-3sdqA:undetectable3lsfE-3sdqA:undetectable | 3lsfB-3sdqA:15.023lsfE-3sdqA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sip | CASPASECASPASE (Drosophilamelanogaster;Drosophilamelanogaster) |
PF00656(Peptidase_C14)PF00656(Peptidase_C14) | 3 | ASP A 45ASN A 27SER B 192 | None | 0.96A | 3lsfB-3sipA:undetectable3lsfE-3sipA:undetectable | 3lsfB-3sipA:19.623lsfE-3sipA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thw | DNA MISMATCH REPAIRPROTEIN MSH3 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05192(MutS_III) | 3 | ASP B 398ASN B 376SER B 403 | None | 1.02A | 3lsfB-3thwB:undetectable3lsfE-3thwB:undetectable | 3lsfB-3thwB:14.683lsfE-3thwB:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tyg | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 3 | ASP A 27ASN A 83SER A 154 | None | 0.93A | 3lsfB-3tygA:undetectable3lsfE-3tygA:undetectable | 3lsfB-3tygA:20.083lsfE-3tygA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w3a | V-TYPE ATP SYNTHASEBETA CHAIN (Thermusthermophilus) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 3 | ASP D 259ASN D 262SER D 156 | None | 0.74A | 3lsfB-3w3aD:undetectable3lsfE-3w3aD:undetectable | 3lsfB-3w3aD:20.523lsfE-3w3aD:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 3 | ASP A 239ASN A 59SER A 218 | None | 1.01A | 3lsfB-4ainA:undetectable3lsfE-4ainA:undetectable | 3lsfB-4ainA:19.673lsfE-4ainA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 3 | ASP A 192ASN A 196SER A 224 | None | 0.81A | 3lsfB-4bb9A:undetectable3lsfE-4bb9A:undetectable | 3lsfB-4bb9A:17.343lsfE-4bb9A:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ce4 | MRPL38 (Sus scrofa) |
no annotation | 3 | ASP b 222ASN b 220SER b 263 | None | 0.79A | 3lsfB-4ce4b:undetectable3lsfE-4ce4b:undetectable | 3lsfB-4ce4b:18.053lsfE-4ce4b:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cw4 | BETA-KETOACYLSYNTHASE (Pseudomonasaeruginosa) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | ASP A 230ASN A 231SER A 239 | None | 1.01A | 3lsfB-4cw4A:undetectable3lsfE-4cw4A:undetectable | 3lsfB-4cw4A:17.693lsfE-4cw4A:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvz | CYTOTOXICITY-ASSOCIATED IMMUNODOMINANTANTIGEN (Helicobacterpylori) |
no annotation | 3 | ASP A 787ASN A 791SER A 689 | None | 0.81A | 3lsfB-4dvzA:undetectable3lsfE-4dvzA:undetectable | 3lsfB-4dvzA:20.253lsfE-4dvzA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eyg | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNAL (Rhodopseudomonaspalustris) |
PF13458(Peripla_BP_6) | 3 | ASP A 259ASN A 263SER A 279 | None | 0.99A | 3lsfB-4eygA:undetectable3lsfE-4eygA:undetectable | 3lsfB-4eygA:23.023lsfE-4eygA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdd | TRANSPORTIN-1 (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 3 | ASP A 806ASN A 807SER A 841 | None | 0.88A | 3lsfB-4fddA:undetectable3lsfE-4fddA:undetectable | 3lsfB-4fddA:14.223lsfE-4fddA:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4frx | ANAEROBICALLY-INDUCED OUTER MEMBRANEPORIN OPRE (Pseudomonasaeruginosa) |
PF03573(OprD) | 3 | ASP A 311ASN A 164SER A 179 | None | 0.94A | 3lsfB-4frxA:undetectable3lsfE-4frxA:undetectable | 3lsfB-4frxA:19.913lsfE-4frxA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h19 | MANDELATE RACEMASE (Agrobacteriumfabrum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ASP A 144ASN A 142SER A 17 | None | 0.96A | 3lsfB-4h19A:undetectable3lsfE-4h19A:undetectable | 3lsfB-4h19A:23.063lsfE-4h19A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz9 | PUTATIVE CYTOPLASMICPROTEIN (Ralstoniapickettii) |
no annotation | 3 | ASP A 86ASN A 9SER A 88 | None | 0.96A | 3lsfB-4hz9A:undetectable3lsfE-4hz9A:undetectable | 3lsfB-4hz9A:17.963lsfE-4hz9A:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4io6 | AVGLUR1 LIGANDBINDING DOMAIN (Adineta vaga) |
PF00497(SBP_bac_3) | 3 | ASP A 85ASN A 105SER A 17 | MET A 301 (-4.7A)MET A 301 ( 4.9A)None | 0.80A | 3lsfB-4io6A:27.53lsfE-4io6A:27.7 | 3lsfB-4io6A:28.833lsfE-4io6A:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 3 | ASP A1176ASN A1170SER A1142 | None | 0.89A | 3lsfB-4pj3A:undetectable3lsfE-4pj3A:undetectable | 3lsfB-4pj3A:10.713lsfE-4pj3A:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qan | HYPOTHETICAL PROTEIN ([Ruminococcus]gnavus) |
no annotation | 3 | ASP A 72ASN A 71SER A 44 | None | 1.02A | 3lsfB-4qanA:undetectable3lsfE-4qanA:undetectable | 3lsfB-4qanA:22.383lsfE-4qanA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 3 | ASP A 382ASN A 21SER A 331 | None | 0.67A | 3lsfB-4tx8A:undetectable3lsfE-4tx8A:undetectable | 3lsfB-4tx8A:18.843lsfE-4tx8A:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 3 | ASP A 223ASN A 453SER A 273 | None | 0.91A | 3lsfB-4ylrA:undetectable3lsfE-4ylrA:undetectable | 3lsfB-4ylrA:20.783lsfE-4ylrA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqu | CDII TOXIN (Salmonellaenterica) |
PF07262(CdiI) | 3 | ASP B 121ASN B 30SER B 119 | None | 0.95A | 3lsfB-4zquB:undetectable3lsfE-4zquB:undetectable | 3lsfB-4zquB:21.973lsfE-4zquB:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7x | HIV-1 YU2 GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 3 | ASP A 457ASN A 280SER A 365 | None | 0.92A | 3lsfB-5a7xA:undetectable3lsfE-5a7xA:undetectable | 3lsfB-5a7xA:22.263lsfE-5a7xA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c78 | ATP-DRIVEN FLIPPASEPGLK (Campylobacterjejuni) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 3 | ASP A 509ASN A 431SER A 389 | None | 0.84A | 3lsfB-5c78A:undetectable3lsfE-5c78A:undetectable | 3lsfB-5c78A:18.953lsfE-5c78A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfc | VP1VP3 (Cardiovirus B;Cardiovirus B) |
no annotationPF00073(Rhv) | 3 | ASP A 3ASN B 156SER A 11 | None | 1.01A | 3lsfB-5cfcA:undetectable3lsfE-5cfcA:undetectable | 3lsfB-5cfcA:20.493lsfE-5cfcA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d8g | TRYPTOPHANASE (Escherichiacoli) |
PF01212(Beta_elim_lyase) | 3 | ASP A 324ASN A 327SER A 62 | None | 1.02A | 3lsfB-5d8gA:undetectable3lsfE-5d8gA:undetectable | 3lsfB-5d8gA:20.973lsfE-5d8gA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5d | INNER MEMBRANEPROTEIN YEJM (Salmonellaenterica) |
PF00884(Sulfatase)PF11893(DUF3413) | 3 | ASP A 303ASN A 304SER A 351 | None | 0.95A | 3lsfB-5i5dA:undetectable3lsfE-5i5dA:undetectable | 3lsfB-5i5dA:16.703lsfE-5i5dA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | ASP A 321ASN A 408SER A 310 | None | 0.65A | 3lsfB-5ibvA:undetectable3lsfE-5ibvA:undetectable | 3lsfB-5ibvA:21.363lsfE-5ibvA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iva | LPS-ASSEMBLY PROTEINLPTD (Pseudomonasaeruginosa) |
PF04453(OstA_C) | 3 | ASP A 480ASN A 478SER A 380 | None | 0.90A | 3lsfB-5ivaA:undetectable3lsfE-5ivaA:undetectable | 3lsfB-5ivaA:19.043lsfE-5ivaA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iva | LPS-ASSEMBLY PROTEINLPTD (Pseudomonasaeruginosa) |
PF04453(OstA_C) | 3 | ASP A 480ASN A 478SER A 492 | None | 1.02A | 3lsfB-5ivaA:undetectable3lsfE-5ivaA:undetectable | 3lsfB-5ivaA:19.043lsfE-5ivaA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j84 | DIHYDROXY-ACIDDEHYDRATASE (Rhizobiumleguminosarum) |
PF00920(ILVD_EDD) | 3 | ASP A 142ASN A 572SER A 255 | None | 0.99A | 3lsfB-5j84A:1.03lsfE-5j84A:undetectable | 3lsfB-5j84A:18.383lsfE-5j84A:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jmd | HEPARINASE IIIPROTEIN (Bacteroidesthetaiotaomicron) |
PF07940(Hepar_II_III)PF16889(Hepar_II_III_N) | 3 | ASP A 435ASN A 436SER A 354 | None | 0.87A | 3lsfB-5jmdA:undetectable3lsfE-5jmdA:undetectable | 3lsfB-5jmdA:16.853lsfE-5jmdA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdx | METALLOPEPTIDASE (Pseudomonasaeruginosa) |
PF13402(Peptidase_M60) | 3 | ASP A 649ASN A 825SER A 652 | None | 0.87A | 3lsfB-5kdxA:undetectable3lsfE-5kdxA:undetectable | 3lsfB-5kdxA:14.073lsfE-5kdxA:14.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li4 | TAIL SHEATH PROTEIN (Staphylococcusphage 812) |
no annotation | 3 | ASP A 401ASN A 406SER A 78 | None | 0.99A | 3lsfB-5li4A:undetectable3lsfE-5li4A:undetectable | 3lsfB-5li4A:20.043lsfE-5li4A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ljo | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA (Escherichiacoli) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 3 | ASP A 562ASN A 681SER A 557 | None | 0.98A | 3lsfB-5ljoA:undetectable3lsfE-5ljoA:undetectable | 3lsfB-5ljoA:15.793lsfE-5ljoA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkn | NEURAL CELL ADHESIONMOLECULE 1 (Homo sapiens) |
PF00041(fn3) | 3 | ASP A 664ASN A 666SER A 643 | None | 0.89A | 3lsfB-5lknA:undetectable3lsfE-5lknA:undetectable | 3lsfB-5lknA:15.123lsfE-5lknA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m10 | CYCLOHEXANONEMONOOXYGENASE FROMTHERMOCRISPUMMUNICIPALE (Thermocrispummunicipale) |
PF07992(Pyr_redox_2) | 3 | ASP A 59ASN A 277SER A 188 | NAP A 602 ( 2.9A)NoneNAP A 602 (-4.1A) | 0.94A | 3lsfB-5m10A:undetectable3lsfE-5m10A:undetectable | 3lsfB-5m10A:20.153lsfE-5m10A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tqr | POLYCOMB PROTEIN EED (Chaetomiumthermophilum) |
PF00400(WD40) | 3 | ASP A 22ASN A 544SER A 34 | None | 0.82A | 3lsfB-5tqrA:undetectable3lsfE-5tqrA:undetectable | 3lsfB-5tqrA:19.343lsfE-5tqrA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 1ANTIGEN PEPTIDETRANSPORTER 2TAP TRANSPORTERINHIBITOR ICP47 (Homo sapiens;Homo sapiens;Humanalphaherpesvirus1) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF00005(ABC_tran)PF00664(ABC_membrane)PF05363(Herpes_US12) | 3 | ASP X 9ASN B 269SER A 412 | None | 0.95A | 3lsfB-5u1dX:undetectable3lsfE-5u1dX:undetectable | 3lsfB-5u1dX:18.913lsfE-5u1dX:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uyt | ICE-BINDING PROTEIN (Flavobacteriaceaebacterium3519-10) |
no annotation | 3 | ASP A 73ASN A 75SER A 61 | None | 0.93A | 3lsfB-5uytA:undetectable3lsfE-5uytA:undetectable | 3lsfB-5uytA:18.933lsfE-5uytA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdu | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
no annotation | 3 | ASP G 457ASN G 280SER G 365 | None | 0.97A | 3lsfB-5wduG:undetectable3lsfE-5wduG:undetectable | 3lsfB-5wduG:undetectable3lsfE-5wduG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT (Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 3 | ASP A 359ASN A 363SER A 213 | None | 1.00A | 3lsfB-5xbpA:undetectable3lsfE-5xbpA:undetectable | 3lsfB-5xbpA:21.483lsfE-5xbpA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z6o | PROTEASE (Penicilliumcyclopium) |
no annotation | 3 | ASP A 169ASN A 172SER A 201 | None | 0.97A | 3lsfB-5z6oA:undetectable3lsfE-5z6oA:undetectable | 3lsfB-5z6oA:undetectable3lsfE-5z6oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cbp | DH270.6 SINGLE CHAINVARIABLE FRAGMENTMAN9-V3 GLYCOPEPTIDE (Homo sapiens;Humanimmunodeficiencyvirus 1) |
no annotationno annotation | 3 | ASP A 107ASN P 300SER A 109 | None | 1.01A | 3lsfB-6cbpA:undetectable3lsfE-6cbpA:undetectable | 3lsfB-6cbpA:undetectable3lsfE-6cbpA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6es1 | SYNAPTIC VESICLEGLYCOPROTEIN 2C (Homo sapiens) |
no annotation | 3 | ASP B 546ASN B 565SER B 527 | None | 0.93A | 3lsfB-6es1B:undetectable3lsfE-6es1B:undetectable | 3lsfB-6es1B:undetectable3lsfE-6es1B:undetectable |