SIMILAR PATTERNS OF AMINO ACIDS FOR 3LSF_B_PZIB802_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e33 | ARYLSULFATASE A (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 3 | SER P 150ASP P 29ASN P 282 | DDZ P 69 ( 4.9A) MG P 603 (-3.1A) MG P 603 (-2.9A) | 0.97A | 3lsfB-1e33P:0.03lsfE-1e33P:0.2 | 3lsfB-1e33P:18.933lsfE-1e33P:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eth | TRIACYLGLYCEROLACYL-HYDROLASE (Sus scrofa) |
PF00151(Lipase)PF01477(PLAT) | 3 | SER A 334ASP A 273ASN A 93 | None | 0.98A | 3lsfB-1ethA:0.03lsfE-1ethA:undetectable | 3lsfB-1ethA:18.723lsfE-1ethA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jye | LACTOSE OPERONREPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 3 | SER A 191ASP A 149ASN A 125 | None | 0.92A | 3lsfB-1jyeA:2.43lsfE-1jyeA:3.1 | 3lsfB-1jyeA:22.563lsfE-1jyeA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpb | LIPASE (Homo sapiens) |
PF00151(Lipase)PF01477(PLAT) | 3 | SER B 333ASP B 272ASN B 92 | BOG B 452 (-3.5A)NoneNone | 0.99A | 3lsfB-1lpbB:0.03lsfE-1lpbB:0.0 | 3lsfB-1lpbB:18.933lsfE-1lpbB:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nw1 | CHOLINE KINASE (49.2KD) (Caenorhabditiselegans) |
PF01633(Choline_kinase) | 3 | SER A 86ASP A 255ASN A 316 | None | 0.83A | 3lsfB-1nw1A:0.03lsfE-1nw1A:undetectable | 3lsfB-1nw1A:19.363lsfE-1nw1A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o12 | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Thermotogamaritima) |
PF01979(Amidohydro_1) | 3 | SER A 291ASP A 229ASN A 301 | None | 0.92A | 3lsfB-1o12A:0.03lsfE-1o12A:undetectable | 3lsfB-1o12A:22.793lsfE-1o12A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pek | PROTEINASE K (Parengyodontiumalbum) |
PF00082(Peptidase_S8) | 3 | SER E 197ASP E 165ASN E 168 | None | 0.86A | 3lsfB-1pekE:0.43lsfE-1pekE:undetectable | 3lsfB-1pekE:21.143lsfE-1pekE:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgu | ACTIN INTERACTINGPROTEIN 1 (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | SER A 336ASP A 318ASN A 299 | None | 0.98A | 3lsfB-1pguA:undetectable3lsfE-1pguA:undetectable | 3lsfB-1pguA:18.203lsfE-1pguA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz3 | ALPHA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF06964(Alpha-L-AF_C) | 3 | SER A 399ASP A 253ASN A 249 | None | 1.00A | 3lsfB-1pz3A:undetectable3lsfE-1pz3A:undetectable | 3lsfB-1pz3A:18.323lsfE-1pz3A:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1td0 | HEAD DECORATIONPROTEIN (Escherichiavirus Lambda) |
PF02924(HDPD) | 3 | SER A 109ASP A 19ASN A 18 | None | 1.01A | 3lsfB-1td0A:undetectable3lsfE-1td0A:undetectable | 3lsfB-1td0A:20.483lsfE-1td0A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlf | LAC REPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 3 | SER A 191ASP A 149ASN A 125 | IPT A 998 ( 4.6A)IPT A 998 (-3.2A)IPT A 998 ( 4.7A) | 0.91A | 3lsfB-1tlfA:undetectable3lsfE-1tlfA:3.5 | 3lsfB-1tlfA:23.653lsfE-1tlfA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1toc | ORNITHODORIN (Ornithodorosmoubata) |
no annotation | 3 | SER R 37ASP R 16ASN R 14 | None | 0.58A | 3lsfB-1tocR:undetectable3lsfE-1tocR:undetectable | 3lsfB-1tocR:16.063lsfE-1tocR:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uag | UDP-N-ACETYLMURAMOYL-L-ALANINE/:D-GLUTAMATE LIGASE (Escherichiacoli) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 3 | SER A 325ASP A 317ASN A 316 | SO4 A 964 ( 4.9A)NoneNone | 0.88A | 3lsfB-1uagA:undetectable3lsfE-1uagA:undetectable | 3lsfB-1uagA:21.363lsfE-1uagA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w07 | ACYL-COA OXIDASE (Arabidopsisthaliana) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 3 | SER A 183ASP A 238ASN A 239 | NoneNoneFAD A1660 (-4.4A) | 0.99A | 3lsfB-1w07A:undetectable3lsfE-1w07A:undetectable | 3lsfB-1w07A:18.513lsfE-1w07A:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yd9 | CORE HISTONEMACRO-H2A.1 (Rattusnorvegicus) |
PF01661(Macro) | 3 | SER A 156ASP A 191ASN A 193 | None | 0.69A | 3lsfB-1yd9A:undetectable3lsfE-1yd9A:undetectable | 3lsfB-1yd9A:20.523lsfE-1yd9A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zy9 | ALPHA-GALACTOSIDASE (Thermotogamaritima) |
PF02065(Melibiase) | 3 | SER A 492ASP A 494ASN A 516 | None | 1.03A | 3lsfB-1zy9A:undetectable3lsfE-1zy9A:undetectable | 3lsfB-1zy9A:20.223lsfE-1zy9A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2atm | HYALURONOGLUCOSAMINIDASE (Vespulavulgaris) |
PF01630(Glyco_hydro_56) | 3 | SER A 38ASP A 45ASN A 97 | None | 0.99A | 3lsfB-2atmA:undetectable3lsfE-2atmA:undetectable | 3lsfB-2atmA:21.083lsfE-2atmA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2au1 | IGG-DEGRADINGPROTEASE (Streptococcuspyogenes) |
PF09028(Mac-1) | 3 | SER A 287ASP A 81ASN A 101 | None | 1.00A | 3lsfB-2au1A:undetectable3lsfE-2au1A:undetectable | 3lsfB-2au1A:21.263lsfE-2au1A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4k | PHOSPHORIBOSYLPYROPHOSPHATESYNTHETASE-ASSOCIATED PROTEIN 1 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 3 | SER A 154ASP A 134ASN A 150 | None | 0.91A | 3lsfB-2c4kA:undetectable3lsfE-2c4kA:undetectable | 3lsfB-2c4kA:21.983lsfE-2c4kA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1c | ISOCITRATEDEHYDROGENASE (Thermusthermophilus) |
PF00180(Iso_dh) | 3 | SER A 154ASP A 442ASN A 399 | None | 0.97A | 3lsfB-2d1cA:undetectable3lsfE-2d1cA:undetectable | 3lsfB-2d1cA:19.683lsfE-2d1cA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddh | ACYL-COA OXIDASE (Rattusnorvegicus) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 3 | SER A 184ASP A 236ASN A 237 | NoneNoneFAD A 699 (-4.0A) | 0.99A | 3lsfB-2ddhA:undetectable3lsfE-2ddhA:undetectable | 3lsfB-2ddhA:17.643lsfE-2ddhA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3x | COAGULATION FACTORX-ACTIVATING ENZYMEHEAVY CHAIN (Daboiasiamensis) |
PF00200(Disintegrin)PF01421(Reprolysin)PF08516(ADAM_CR) | 3 | SER A 22ASP A 66ASN A 69 | NoneNoneNAG A 900 ( 2.0A) | 0.94A | 3lsfB-2e3xA:undetectable3lsfE-2e3xA:undetectable | 3lsfB-2e3xA:18.793lsfE-2e3xA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 3 | SER A 388ASP A 381ASN A 382 | None | 0.96A | 3lsfB-2exaA:undetectable3lsfE-2exaA:undetectable | 3lsfB-2exaA:20.483lsfE-2exaA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3o | PYRUVATEFORMATE-LYASE 2 (Archaeoglobusfulgidus) |
PF01228(Gly_radical)PF02901(PFL-like) | 3 | SER A 773ASP A 666ASN A 594 | None | 0.82A | 3lsfB-2f3oA:undetectable3lsfE-2f3oA:undetectable | 3lsfB-2f3oA:17.653lsfE-2f3oA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsb | RASGTPASE-ACTIVATINGPROTEIN 1 (Homo sapiens) |
PF00017(SH2) | 3 | SER A 24ASP A 47ASN A 48 | None | 0.98A | 3lsfB-2gsbA:undetectable3lsfE-2gsbA:undetectable | 3lsfB-2gsbA:18.523lsfE-2gsbA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj9 | AUTOINDUCER2-BINDINGPERIPLASMIC PROTEINLUXP (Vibrio harveyi) |
PF13407(Peripla_BP_4) | 3 | SER A 207ASP A 136ASN A 159 | NoneNoneAI2 A 501 (-3.3A) | 1.01A | 3lsfB-2hj9A:3.23lsfE-2hj9A:2.5 | 3lsfB-2hj9A:20.113lsfE-2hj9A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsn | METHIONYL-TRNASYNTHETASE,CYTOPLASMICGU4 NUCLEIC-BINDINGPROTEIN 1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF09635(MetRS-N)no annotation | 3 | SER A 4ASP B 55ASN B 56 | None | 0.99A | 3lsfB-2hsnA:undetectable3lsfE-2hsnA:undetectable | 3lsfB-2hsnA:20.463lsfE-2hsnA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p50 | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 3 | SER A 309ASP A 248ASN A 319 | None | 0.92A | 3lsfB-2p50A:undetectable3lsfE-2p50A:undetectable | 3lsfB-2p50A:21.143lsfE-2p50A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfo | NUCLEOPORIN NIC96 (Saccharomycescerevisiae) |
PF04097(Nic96) | 3 | SER A 421ASP A 419ASN A 395 | None | 0.87A | 3lsfB-2rfoA:undetectable3lsfE-2rfoA:undetectable | 3lsfB-2rfoA:17.213lsfE-2rfoA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x98 | ALKALINE PHOSPHATASE (Halobacteriumsalinarum) |
PF00245(Alk_phosphatase) | 3 | SER A 375ASP A 261ASN A 268 | None | 0.79A | 3lsfB-2x98A:undetectable3lsfE-2x98A:undetectable | 3lsfB-2x98A:19.033lsfE-2x98A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yoc | PULLULANASE (Klebsiellaoxytoca) |
PF02922(CBM_48)PF03714(PUD)PF11852(DUF3372) | 3 | SER A 327ASP A 242ASN A 240 | NoneSO4 A2078 (-4.4A)None | 1.00A | 3lsfB-2yocA:undetectable3lsfE-2yocA:undetectable | 3lsfB-2yocA:13.073lsfE-2yocA:13.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckm | YRAM (HI1655) (Haemophilusinfluenzae) |
PF04348(LppC) | 3 | SER A 549ASP A 559ASN A 371 | None | 0.98A | 3lsfB-3ckmA:undetectable3lsfE-3ckmA:undetectable | 3lsfB-3ckmA:19.943lsfE-3ckmA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clk | TRANSCRIPTIONREGULATOR (Lactobacillusplantarum) |
PF13377(Peripla_BP_3) | 3 | SER A 288ASP A 247ASN A 74 | None | 0.99A | 3lsfB-3clkA:undetectable3lsfE-3clkA:2.7 | 3lsfB-3clkA:22.873lsfE-3clkA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6i | MONOTHIOLGLUTAREDOXIN-3 (Saccharomycescerevisiae) |
PF00085(Thioredoxin) | 3 | SER A 67ASP A 97ASN A 42 | None | 1.03A | 3lsfB-3d6iA:undetectable3lsfE-3d6iA:undetectable | 3lsfB-3d6iA:17.063lsfE-3d6iA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d7r | ESTERASE (Staphylococcusaureus) |
PF07859(Abhydrolase_3) | 3 | SER A 188ASP A 184ASN A 230 | None | 0.83A | 3lsfB-3d7rA:undetectable3lsfE-3d7rA:undetectable | 3lsfB-3d7rA:18.603lsfE-3d7rA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwk | PENICILLIN-BINDINGPROTEIN 2 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF00912(Transgly) | 3 | SER A 297ASP A 348ASN A 349 | None | 1.02A | 3lsfB-3dwkA:undetectable3lsfE-3dwkA:undetectable | 3lsfB-3dwkA:17.163lsfE-3dwkA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egj | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Vibrio cholerae) |
PF01979(Amidohydro_1) | 3 | SER A 306ASP A 245ASN A 316 | None | 0.86A | 3lsfB-3egjA:undetectable3lsfE-3egjA:undetectable | 3lsfB-3egjA:23.513lsfE-3egjA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw8 | RETICULINE OXIDASE (Eschscholziacalifornica) |
PF01565(FAD_binding_4)PF08031(BBE) | 3 | SER A 57ASP A 121ASN A 124 | NoneNoneNAG A 521 (-2.9A) | 0.91A | 3lsfB-3fw8A:undetectable3lsfE-3fw8A:undetectable | 3lsfB-3fw8A:21.413lsfE-3fw8A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 3 | SER A 86ASP A 487ASN A 484 | None | 0.95A | 3lsfB-3h7lA:undetectable3lsfE-3h7lA:undetectable | 3lsfB-3h7lA:16.843lsfE-3h7lA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETACARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica;Moorellathermoacetica) |
PF03063(Prismane)PF03598(CdhC) | 3 | SER M 34ASP A 226ASN A 225 | None | 0.98A | 3lsfB-3i04M:undetectable3lsfE-3i04M:undetectable | 3lsfB-3i04M:18.313lsfE-3i04M:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i12 | D-ALANINE-D-ALANINELIGASE A (Salmonellaenterica) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 3 | SER A 115ASP A 113ASN A 188 | None | 0.99A | 3lsfB-3i12A:undetectable3lsfE-3i12A:undetectable | 3lsfB-3i12A:21.993lsfE-3i12A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i12 | D-ALANINE-D-ALANINELIGASE A (Salmonellaenterica) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 3 | SER A 326ASP A 263ASN A 264 | None | 0.91A | 3lsfB-3i12A:undetectable3lsfE-3i12A:undetectable | 3lsfB-3i12A:21.993lsfE-3i12A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3t | UBIQUITINCARBOXYL-TERMINALHYDROLASE 21 (Homo sapiens) |
PF00443(UCH) | 3 | SER A 494ASP A 352ASN A 356 | None | 0.77A | 3lsfB-3i3tA:undetectable3lsfE-3i3tA:undetectable | 3lsfB-3i3tA:21.013lsfE-3i3tA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 4 (Thermusthermophilus) |
PF00346(Complex1_49kDa) | 3 | SER 4 128ASP 4 401ASN 4 377 | None | 0.94A | 3lsfB-3i9v4:undetectable3lsfE-3i9v4:undetectable | 3lsfB-3i9v4:20.623lsfE-3i9v4:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9e | VP5 (Bluetonguevirus) |
PF00901(Orbi_VP5) | 3 | SER D 305ASP D 472ASN D 476 | None | 0.39A | 3lsfB-3j9eD:undetectable3lsfE-3j9eD:undetectable | 3lsfB-3j9eD:19.083lsfE-3j9eD:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42PRE-MRNA-SPLICINGFACTOR CWF14 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV)PF01423(LSM) | 3 | SER A 509ASP A 81ASN e 87 | NoneNone G C 75 ( 4.7A) | 0.94A | 3lsfB-3jb9A:undetectable3lsfE-3jb9A:undetectable | 3lsfB-3jb9A:7.593lsfE-3jb9A:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jwo | HIV-1 GP120 ENVELOPEGLYCOPROTEIN (Homo sapiens) |
PF00516(GP120) | 3 | SER A 365ASP A 457ASN A 462 | None | 0.89A | 3lsfB-3jwoA:undetectable3lsfE-3jwoA:undetectable | 3lsfB-3jwoA:20.383lsfE-3jwoA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhx | KETODEOXYGLUCONOKINASE (Shigellaflexneri) |
PF00294(PfkB) | 3 | SER A 210ASP A 102ASN A 105 | None | 0.84A | 3lsfB-3lhxA:undetectable3lsfE-3lhxA:undetectable | 3lsfB-3lhxA:22.333lsfE-3lhxA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mz1 | PUTATIVETRANSCRIPTIONALREGULATOR (Sinorhizobiummeliloti) |
PF03466(LysR_substrate) | 3 | SER A 94ASP A 123ASN A 218 | None | 0.82A | 3lsfB-3mz1A:7.93lsfE-3mz1A:8.0 | 3lsfB-3mz1A:21.543lsfE-3mz1A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6x | PUTATIVEGLUTATHIONYLSPERMIDINE SYNTHASE (Methylobacillusflagellatus) |
PF14403(CP_ATPgrasp_2) | 3 | SER A 349ASP A 321ASN A 123 | None | 0.97A | 3lsfB-3n6xA:undetectable3lsfE-3n6xA:undetectable | 3lsfB-3n6xA:19.673lsfE-3n6xA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3m | BETA SUBUNIT2-HYDROXYACYL-COADEHYDRATASE (Clostridioidesdifficile) |
PF06050(HGD-D) | 3 | SER B 73ASP B 352ASN B 358 | None | 1.02A | 3lsfB-3o3mB:undetectable3lsfE-3o3mB:undetectable | 3lsfB-3o3mB:19.903lsfE-3o3mB:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4r | DEHYDROGENASE/REDUCTASE SDR FAMILYMEMBER 4 (Homo sapiens) |
PF13561(adh_short_C2) | 3 | SER A 218ASP A 42ASN A 68 | NAP A 601 ( 4.4A)NAP A 601 (-3.9A)NAP A 601 (-3.8A) | 1.02A | 3lsfB-3o4rA:undetectable3lsfE-3o4rA:undetectable | 3lsfB-3o4rA:22.343lsfE-3o4rA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6p | PEPTIDE ABCTRANSPORTER,PEPTIDE-BINDINGPROTEIN (Enterococcusfaecalis) |
PF00496(SBP_bac_5) | 3 | SER A 492ASP A 466ASN A 472 | None | 0.83A | 3lsfB-3o6pA:undetectable3lsfE-3o6pA:1.4 | 3lsfB-3o6pA:21.373lsfE-3o6pA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojy | COMPLEMENT COMPONENTC8 BETA CHAIN (Homo sapiens) |
PF00057(Ldl_recept_a)PF00090(TSP_1)PF01823(MACPF) | 3 | SER B 232ASP B 491ASN B 515 | None | 0.87A | 3lsfB-3ojyB:undetectable3lsfE-3ojyB:undetectable | 3lsfB-3ojyB:19.723lsfE-3ojyB:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ono | RIBOSE/GALACTOSEISOMERASE (Vibrioparahaemolyticus) |
PF02502(LacAB_rpiB)PF12408(DUF3666) | 3 | SER A 186ASP A 43ASN A 15 | None | 0.98A | 3lsfB-3onoA:undetectable3lsfE-3onoA:undetectable | 3lsfB-3onoA:22.273lsfE-3onoA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oyo | HEMOPEXIN FOLDPROTEIN CP4 (Vignaunguiculata) |
PF00045(Hemopexin) | 3 | SER A 119ASP A 65ASN A 7 | NoneNone CA A 228 (-3.5A) | 0.99A | 3lsfB-3oyoA:undetectable3lsfE-3oyoA:undetectable | 3lsfB-3oyoA:23.963lsfE-3oyoA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozy | PUTATIVE MANDELATERACEMASE (Bordetellabronchiseptica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | SER A 53ASP A 308ASN A 335 | None | 1.02A | 3lsfB-3ozyA:undetectable3lsfE-3ozyA:undetectable | 3lsfB-3ozyA:21.353lsfE-3ozyA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5p | TAXADIENE SYNTHASE (Taxusbrevifolia) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | SER A 313ASP A 141ASN A 195 | None | 0.96A | 3lsfB-3p5pA:undetectable3lsfE-3p5pA:undetectable | 3lsfB-3p5pA:15.023lsfE-3p5pA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 3 | SER A 164ASP A 98ASN A 31 | GOL A 523 (-4.2A)NoneNone | 1.02A | 3lsfB-3pfeA:undetectable3lsfE-3pfeA:undetectable | 3lsfB-3pfeA:20.773lsfE-3pfeA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r11 | ENZYME OF ENOLASESUPERFAMILY (Francisellaphilomiragia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | SER A 137ASP A 321ASN A 267 | None | 0.98A | 3lsfB-3r11A:undetectable3lsfE-3r11A:undetectable | 3lsfB-3r11A:20.683lsfE-3r11A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sip | CASPASECASPASE (Drosophilamelanogaster;Drosophilamelanogaster) |
PF00656(Peptidase_C14)PF00656(Peptidase_C14) | 3 | SER B 192ASP A 45ASN A 27 | None | 1.03A | 3lsfB-3sipB:undetectable3lsfE-3sipB:undetectable | 3lsfB-3sipB:16.153lsfE-3sipB:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thw | DNA MISMATCH REPAIRPROTEIN MSH3 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05192(MutS_III) | 3 | SER B 403ASP B 398ASN B 376 | None | 1.01A | 3lsfB-3thwB:undetectable3lsfE-3thwB:undetectable | 3lsfB-3thwB:14.683lsfE-3thwB:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tyg | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 3 | SER A 154ASP A 27ASN A 83 | None | 1.00A | 3lsfB-3tygA:undetectable3lsfE-3tygA:undetectable | 3lsfB-3tygA:20.083lsfE-3tygA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w3a | V-TYPE ATP SYNTHASEBETA CHAIN (Thermusthermophilus) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 3 | SER D 156ASP D 259ASN D 262 | None | 0.67A | 3lsfB-3w3aD:undetectable3lsfE-3w3aD:undetectable | 3lsfB-3w3aD:20.523lsfE-3w3aD:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 3 | SER A 224ASP A 192ASN A 196 | None | 0.85A | 3lsfB-4bb9A:undetectable3lsfE-4bb9A:undetectable | 3lsfB-4bb9A:17.343lsfE-4bb9A:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ce4 | MRPL38 (Sus scrofa) |
no annotation | 3 | SER b 263ASP b 222ASN b 220 | None | 0.82A | 3lsfB-4ce4b:undetectable3lsfE-4ce4b:undetectable | 3lsfB-4ce4b:18.053lsfE-4ce4b:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cw4 | BETA-KETOACYLSYNTHASE (Pseudomonasaeruginosa) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | SER A 239ASP A 230ASN A 231 | None | 0.99A | 3lsfB-4cw4A:undetectable3lsfE-4cw4A:undetectable | 3lsfB-4cw4A:17.693lsfE-4cw4A:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvz | CYTOTOXICITY-ASSOCIATED IMMUNODOMINANTANTIGEN (Helicobacterpylori) |
no annotation | 3 | SER A 689ASP A 787ASN A 791 | None | 0.79A | 3lsfB-4dvzA:undetectable3lsfE-4dvzA:undetectable | 3lsfB-4dvzA:20.253lsfE-4dvzA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdd | TRANSPORTIN-1 (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 3 | SER A 841ASP A 806ASN A 807 | None | 0.81A | 3lsfB-4fddA:undetectable3lsfE-4fddA:undetectable | 3lsfB-4fddA:14.223lsfE-4fddA:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h19 | MANDELATE RACEMASE (Agrobacteriumfabrum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | SER A 17ASP A 144ASN A 142 | None | 0.98A | 3lsfB-4h19A:undetectable3lsfE-4h19A:undetectable | 3lsfB-4h19A:23.063lsfE-4h19A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz9 | PUTATIVE CYTOPLASMICPROTEIN (Ralstoniapickettii) |
no annotation | 3 | SER A 88ASP A 86ASN A 9 | None | 1.01A | 3lsfB-4hz9A:undetectable3lsfE-4hz9A:undetectable | 3lsfB-4hz9A:17.963lsfE-4hz9A:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4io6 | AVGLUR1 LIGANDBINDING DOMAIN (Adineta vaga) |
PF00497(SBP_bac_3) | 3 | SER A 17ASP A 85ASN A 105 | NoneMET A 301 (-4.7A)MET A 301 ( 4.9A) | 0.85A | 3lsfB-4io6A:27.53lsfE-4io6A:27.7 | 3lsfB-4io6A:28.833lsfE-4io6A:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | SILKWORM STORAGEPROTEIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 3 | SER A 194ASP A 204ASN A 201 | None | 0.94A | 3lsfB-4l37A:undetectable3lsfE-4l37A:undetectable | 3lsfB-4l37A:17.403lsfE-4l37A:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 3 | SER A1142ASP A1176ASN A1170 | None | 0.95A | 3lsfB-4pj3A:undetectable3lsfE-4pj3A:undetectable | 3lsfB-4pj3A:10.713lsfE-4pj3A:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qan | HYPOTHETICAL PROTEIN ([Ruminococcus]gnavus) |
no annotation | 3 | SER A 44ASP A 72ASN A 71 | None | 0.99A | 3lsfB-4qanA:undetectable3lsfE-4qanA:undetectable | 3lsfB-4qanA:22.383lsfE-4qanA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s2u | RIBOSE-PHOSPHATEPYROPHOSPHOKINASE (Escherichiacoli) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 3 | SER A 149ASP A 129ASN A 145 | None | 1.01A | 3lsfB-4s2uA:undetectable3lsfE-4s2uA:undetectable | 3lsfB-4s2uA:23.513lsfE-4s2uA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 3 | SER A 331ASP A 382ASN A 21 | None | 0.70A | 3lsfB-4tx8A:undetectable3lsfE-4tx8A:undetectable | 3lsfB-4tx8A:18.843lsfE-4tx8A:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 3 | SER A 273ASP A 223ASN A 453 | None | 0.96A | 3lsfB-4ylrA:undetectable3lsfE-4ylrA:undetectable | 3lsfB-4ylrA:20.783lsfE-4ylrA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqu | CDII TOXIN (Salmonellaenterica) |
PF07262(CdiI) | 3 | SER B 119ASP B 121ASN B 30 | None | 0.92A | 3lsfB-4zquB:undetectable3lsfE-4zquB:undetectable | 3lsfB-4zquB:21.973lsfE-4zquB:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7x | HIV-1 YU2 GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 3 | SER A 365ASP A 457ASN A 280 | None | 0.95A | 3lsfB-5a7xA:undetectable3lsfE-5a7xA:undetectable | 3lsfB-5a7xA:22.263lsfE-5a7xA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c78 | ATP-DRIVEN FLIPPASEPGLK (Campylobacterjejuni) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 3 | SER A 389ASP A 509ASN A 431 | None | 0.84A | 3lsfB-5c78A:undetectable3lsfE-5c78A:undetectable | 3lsfB-5c78A:18.953lsfE-5c78A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fp1 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | SER A 462ASP A 513ASN A 558 | None | 0.99A | 3lsfB-5fp1A:undetectable3lsfE-5fp1A:undetectable | 3lsfB-5fp1A:18.263lsfE-5fp1A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5d | INNER MEMBRANEPROTEIN YEJM (Salmonellaenterica) |
PF00884(Sulfatase)PF11893(DUF3413) | 3 | SER A 351ASP A 303ASN A 304 | None | 1.02A | 3lsfB-5i5dA:undetectable3lsfE-5i5dA:undetectable | 3lsfB-5i5dA:16.703lsfE-5i5dA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | SER A 310ASP A 321ASN A 408 | None | 0.68A | 3lsfB-5ibvA:undetectable3lsfE-5ibvA:undetectable | 3lsfB-5ibvA:21.363lsfE-5ibvA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iva | LPS-ASSEMBLY PROTEINLPTD (Pseudomonasaeruginosa) |
PF04453(OstA_C) | 3 | SER A 380ASP A 480ASN A 478 | None | 0.85A | 3lsfB-5ivaA:undetectable3lsfE-5ivaA:undetectable | 3lsfB-5ivaA:19.043lsfE-5ivaA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j39 | TUDOR AND KHDOMAIN-CONTAININGPROTEIN (Homo sapiens) |
PF00567(TUDOR) | 3 | SER A 313ASP A 393ASN A 394 | NoneCAC A 501 (-3.6A)None | 0.97A | 3lsfB-5j39A:undetectable3lsfE-5j39A:undetectable | 3lsfB-5j39A:23.353lsfE-5j39A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jmd | HEPARINASE IIIPROTEIN (Bacteroidesthetaiotaomicron) |
PF07940(Hepar_II_III)PF16889(Hepar_II_III_N) | 3 | SER A 354ASP A 435ASN A 436 | None | 0.84A | 3lsfB-5jmdA:undetectable3lsfE-5jmdA:undetectable | 3lsfB-5jmdA:16.853lsfE-5jmdA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5la0 | CARBOHYDRATE BINDINGFAMILY 6 (Ruminiclostridiumthermocellum) |
PF00150(Cellulase)PF03422(CBM_6) | 3 | SER A 426ASP A 392ASN A 386 | None CA A 604 ( 2.4A)None | 1.03A | 3lsfB-5la0A:undetectable3lsfE-5la0A:undetectable | 3lsfB-5la0A:20.823lsfE-5la0A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li4 | TAIL SHEATH PROTEIN (Staphylococcusphage 812) |
no annotation | 3 | SER A 78ASP A 401ASN A 406 | None | 0.99A | 3lsfB-5li4A:undetectable3lsfE-5li4A:undetectable | 3lsfB-5li4A:20.043lsfE-5li4A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ljo | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA (Escherichiacoli) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 3 | SER A 557ASP A 562ASN A 681 | None | 0.97A | 3lsfB-5ljoA:undetectable3lsfE-5ljoA:undetectable | 3lsfB-5ljoA:15.793lsfE-5ljoA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkn | NEURAL CELL ADHESIONMOLECULE 1 (Homo sapiens) |
PF00041(fn3) | 3 | SER A 643ASP A 664ASN A 666 | None | 0.97A | 3lsfB-5lknA:undetectable3lsfE-5lknA:undetectable | 3lsfB-5lknA:15.123lsfE-5lknA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m10 | CYCLOHEXANONEMONOOXYGENASE FROMTHERMOCRISPUMMUNICIPALE (Thermocrispummunicipale) |
PF07992(Pyr_redox_2) | 3 | SER A 188ASP A 59ASN A 277 | NAP A 602 (-4.1A)NAP A 602 ( 2.9A)None | 0.95A | 3lsfB-5m10A:undetectable3lsfE-5m10A:undetectable | 3lsfB-5m10A:20.153lsfE-5m10A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tqr | POLYCOMB PROTEIN EED (Chaetomiumthermophilum) |
PF00400(WD40) | 3 | SER A 34ASP A 22ASN A 544 | None | 0.82A | 3lsfB-5tqrA:undetectable3lsfE-5tqrA:undetectable | 3lsfB-5tqrA:19.343lsfE-5tqrA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 1ANTIGEN PEPTIDETRANSPORTER 2TAP TRANSPORTERINHIBITOR ICP47 (Homo sapiens;Homo sapiens;Humanalphaherpesvirus1) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF00005(ABC_tran)PF00664(ABC_membrane)PF05363(Herpes_US12) | 3 | SER A 412ASP X 9ASN B 269 | None | 0.92A | 3lsfB-5u1dA:undetectable3lsfE-5u1dA:undetectable | 3lsfB-5u1dA:16.583lsfE-5u1dA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uyt | ICE-BINDING PROTEIN (Flavobacteriaceaebacterium3519-10) |
no annotation | 3 | SER A 61ASP A 73ASN A 75 | None | 0.94A | 3lsfB-5uytA:undetectable3lsfE-5uytA:undetectable | 3lsfB-5uytA:18.933lsfE-5uytA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT (Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 3 | SER A 213ASP A 359ASN A 363 | None | 1.01A | 3lsfB-5xbpA:undetectable3lsfE-5xbpA:undetectable | 3lsfB-5xbpA:21.483lsfE-5xbpA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT3NT OXYGENASE BETASUBUNIT (Diaphorobactersp. DS2;Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A)PF00866(Ring_hydroxyl_B) | 3 | SER A 260ASP A 262ASN C 90 | None | 1.03A | 3lsfB-5xbpA:undetectable3lsfE-5xbpA:undetectable | 3lsfB-5xbpA:21.483lsfE-5xbpA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsz | LYSOPHOSPHATIDICACID RECEPTOR6A,ENDOLYSIN,LYSOPHOSPHATIDIC ACIDRECEPTOR 6A (Danio rerio;Escherichiavirus T4) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 3 | SER A 113ASP A 298ASN A 45 | None | 0.99A | 3lsfB-5xszA:undetectable3lsfE-5xszA:undetectable | 3lsfB-5xszA:18.073lsfE-5xszA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z6o | PROTEASE (Penicilliumcyclopium) |
no annotation | 3 | SER A 201ASP A 169ASN A 172 | None | 0.94A | 3lsfB-5z6oA:undetectable3lsfE-5z6oA:undetectable | 3lsfB-5z6oA:undetectable3lsfE-5z6oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT B (Flavobacteriumjohnsoniae) |
no annotation | 3 | SER B 986ASP B 959ASN B 963 | None | 1.02A | 3lsfB-6btmB:undetectable3lsfE-6btmB:undetectable | 3lsfB-6btmB:undetectable3lsfE-6btmB:undetectable |