SIMILAR PATTERNS OF AMINO ACIDS FOR 3LCV_B_SAMB301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9h PROTEIN
(3-AMINO-5-HYDROXYBE
NZOIC ACID SYNTHASE)

(Amycolatopsis
mediterranei) 		PF01041
(DegT_DnrJ_EryC1) 		3 ARG A  25
ASP A  16
GLN A 255
 None
 0.92A 3lcvB-1b9hA:
undetectable		 3lcvB-1b9hA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2z DEATH DOMAIN OF
PELLE

(Drosophila
melanogaster) 		PF00531
(Death) 		3 ARG A  78
ASP A  67
GLN A  93
 None
 0.84A 3lcvB-1d2zA:
undetectable		 3lcvB-1d2zA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5n INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		3 ARG A 292
ASP A 538
GLN A 381
 None
 0.94A 3lcvB-1f5nA:
undetectable		 3lcvB-1f5nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE

(Pagrus major) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		3 ARG A 669
ASP A 487
GLN A 524
 None
 0.91A 3lcvB-1g0dA:
undetectable		 3lcvB-1g0dA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h3g CYCLOMALTODEXTRINASE

(Flavobacterium
sp. 92) 		PF00128
(Alpha-amylase)
PF09087
(Cyc-maltodext_N)
PF10438
(Cyc-maltodext_C) 		3 ARG A 253
ASP A 418
GLN A 448
 None
 0.95A 3lcvB-1h3gA:
undetectable		 3lcvB-1h3gA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hjv CHITINASE-3 LIKE
PROTEIN 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		3 ARG A 246
ASP A 232
GLN A 314
 None
 0.91A 3lcvB-1hjvA:
undetectable		 3lcvB-1hjvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		3 ARG A 261
ASP A 462
GLN A 246
 None
 0.85A 3lcvB-1hn0A:
undetectable		 3lcvB-1hn0A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jd3 CHORISMATE LYASE

(Escherichia
coli) 		PF04345
(Chor_lyase) 		3 ARG A 126
ASP A  26
GLN A  41
 None
 0.84A 3lcvB-1jd3A:
undetectable		 3lcvB-1jd3A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kol FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A 222
ASP A  49
GLN A 337
 NAD  A1403 (-3.2A)
None
NAD  A1403 (-4.3A)
 0.87A 3lcvB-1kolA:
3.4		 3lcvB-1kolA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mgt PROTEIN
(O6-METHYLGUANINE-DN
A METHYLTRANSFERASE)

(Thermococcus
kodakarensis) 		PF01035
(DNA_binding_1)
PF09153
(DUF1938) 		3 ARG A  33
ASP A  57
GLN A  25
 None
 0.90A 3lcvB-1mgtA:
undetectable		 3lcvB-1mgtA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1muu GDP-MANNOSE
6-DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		3 ARG A 122
ASP A 169
GLN A  57
 None
 0.75A 3lcvB-1muuA:
3.0		 3lcvB-1muuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		3 ARG A 103
ASP A 334
GLN A 391
 None
 0.90A 3lcvB-1oltA:
undetectable		 3lcvB-1oltA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6b CLPA PROTEIN

(Escherichia
coli) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		3 ARG X 697
ASP X 656
GLN X 684
 None
 0.91A 3lcvB-1r6bX:
undetectable		 3lcvB-1r6bX:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sj8 TALIN 1

(Mus musculus) 		PF09141
(Talin_middle) 		3 ARG A 741
ASP A 564
GLN A 701
 None
 0.90A 3lcvB-1sj8A:
undetectable		 3lcvB-1sj8A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmc CLASS I
HISTOCOMPATIBILITY
ANTIGEN (HLA-AW68)

(Homo sapiens) 		PF00129
(MHC_I) 		3 ARG A 114
ASP A 137
GLN A  87
 None
 0.87A 3lcvB-1tmcA:
undetectable		 3lcvB-1tmcA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vg0 RAB PROTEINS
GERANYLGERANYLTRANSF
ERASE COMPONENT A 1

(Rattus
norvegicus) 		PF00996
(GDI) 		3 ARG A 485
ASP A 553
GLN A 587
 None
 0.91A 3lcvB-1vg0A:
undetectable		 3lcvB-1vg0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmw GERANYLGERANYL
DIPHOSPHATE
SYNTHETASE

(Thermus
thermophilus) 		PF00348
(polyprenyl_synt) 		3 ARG A 328
ASP A 230
GLN A 146
 None
 0.73A 3lcvB-1wmwA:
undetectable		 3lcvB-1wmwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN
PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 ARG B 362
ASP B  33
GLN A 254
 None
 0.70A 3lcvB-2amcB:
undetectable		 3lcvB-2amcB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e11 HYDROLASE

(Xanthomonas
campestris) 		PF00795
(CN_hydrolase) 		3 ARG A 179
ASP A 207
GLN A  84
 None
 0.73A 3lcvB-2e11A:
undetectable		 3lcvB-2e11A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ej5 ENOYL-COA HYDRATASE
SUBUNIT II

(Geobacillus
kaustophilus) 		PF00378
(ECH_1) 		3 ARG A 252
ASP A 240
GLN A  14
 None
 0.87A 3lcvB-2ej5A:
undetectable		 3lcvB-2ej5A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT A
ADENYLYLSULFATE
REDUCTASE, SUBUNIT B

(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
PF12139
(APS-reductase_C)
PF13187
(Fer4_9) 		3 ARG A 563
ASP B 745
GLN A 522
 None
 0.93A 3lcvB-2fjaA:
undetectable		 3lcvB-2fjaA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1

(Homo sapiens) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		3 ARG A  23
ASP A 147
GLN A 235
 None
 0.80A 3lcvB-2nn6A:
undetectable		 3lcvB-2nn6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o14 HYPOTHETICAL PROTEIN
YXIM

(Bacillus
subtilis) 		PF13472
(Lipase_GDSL_2) 		3 ARG A 345
ASP A 121
GLN A 201
 None
 0.60A 3lcvB-2o14A:
undetectable		 3lcvB-2o14A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		3 ARG A  78
ASP A  37
GLN A 221
 SO4  A 323 (-2.8A)
None
NAD  A 400 (-3.4A)
 0.91A 3lcvB-2o2zA:
3.0		 3lcvB-2o2zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		3 ARG A  78
ASP A  56
GLN A 221
 SO4  A 323 (-2.8A)
SO4  A 324 ( 4.6A)
NAD  A 400 (-3.4A)
 0.92A 3lcvB-2o2zA:
3.0		 3lcvB-2o2zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ARG A 529
ASP A 247
GLN A 589
 None
 0.81A 3lcvB-2ongA:
undetectable		 3lcvB-2ongA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4f SIMILAR TO SP|P32453
SACCHAROMYCES
CEREVISIAE YNL315C
ATP11

([Candida]
glabrata) 		PF06644
(ATP11) 		3 ARG A 162
ASP A 238
GLN A 234
 None
 0.93A 3lcvB-2p4fA:
undetectable		 3lcvB-2p4fA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 3 ARG A 627
ASP A 741
GLN A 724
 None
 0.73A 3lcvB-2po4A:
undetectable		 3lcvB-2po4A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppv UNCHARACTERIZED
PROTEIN

(Staphylococcus
epidermidis) 		PF01933
(UPF0052) 		3 ARG A  78
ASP A  37
GLN A 220
 None
 0.92A 3lcvB-2ppvA:
2.4		 3lcvB-2ppvA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyv XAA-HIS DIPEPTIDASE

(Histophilus
somni) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ARG A 366
ASP A 115
GLN A  74
 SO4  A 503 (-3.0A)
ZN  A 501 ( 2.6A)
None
 0.84A 3lcvB-2qyvA:
undetectable		 3lcvB-2qyvA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans) 		PF07971
(Glyco_hydro_92) 		3 ARG A 436
ASP A 428
GLN A 376
 None
 0.76A 3lcvB-2xsgA:
undetectable		 3lcvB-2xsgA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yia RNA-DIRECTED RNA
POLYMERASE

(Infectious
pancreatic
necrosis virus) 		PF04197
(Birna_RdRp) 		3 ARG A 695
ASP A 707
GLN A 394
 None
 0.94A 3lcvB-2yiaA:
undetectable		 3lcvB-2yiaA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akz GLUTAMYL-TRNA
SYNTHETASE 2

(Thermotoga
maritima) 		no annotation 3 ARG B  70
ASP B 219
GLN B 227
 C  F  75 ( 3.5A)
GSU  B1001 (-4.0A)
None
 0.91A 3lcvB-3akzB:
undetectable		 3lcvB-3akzB:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al2 DNA TOPOISOMERASE
2-BINDING PROTEIN 1

(Homo sapiens) 		PF00533
(BRCT) 		3 ARG A1407
ASP A1471
GLN A1366
 None
 0.89A 3lcvB-3al2A:
undetectable		 3lcvB-3al2A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ch0 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Cytophaga
hutchinsonii) 		PF03009
(GDPD) 		3 ARG A 102
ASP A  42
GLN A  11
 GOL  A 289 (-2.7A)
CIT  A 272 (-3.7A)
None
 0.76A 3lcvB-3ch0A:
undetectable		 3lcvB-3ch0A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmg PUTATIVE
BETA-GALACTOSIDASE

(Bacteroides
fragilis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		3 ARG A 455
ASP A 368
GLN A 278
 None
 0.88A 3lcvB-3cmgA:
undetectable		 3lcvB-3cmgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		3 ARG A1341
ASP A1170
GLN A1096
 None
 0.93A 3lcvB-3ecqA:
undetectable		 3lcvB-3ecqA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed5 YFNB

(Bacillus
subtilis) 		PF13419
(HAD_2) 		3 ARG A 132
ASP A 181
GLN A  50
 None
 0.94A 3lcvB-3ed5A:
2.5		 3lcvB-3ed5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fch CARBOXYSOME SHELL
PROTEIN CSOS1D

(Prochlorococcus
marinus) 		PF00936
(BMC) 		3 ARG A 248
ASP A 238
GLN A  68
 None
 0.74A 3lcvB-3fchA:
undetectable		 3lcvB-3fchA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxg RHAMNONATE
DEHYDRATASE

(Fusarium
graminearum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ARG A  55
ASP A 297
GLN A 343
 None
 0.86A 3lcvB-3fxgA:
undetectable		 3lcvB-3fxgA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fzg 16S RRNA METHYLASE

(Escherichia
coli) 		PF07091
(FmrO) 		3 ARG A  89
ASP A 137
GLN A 188
 SAM  A 300 (-2.9A)
SAM  A 300 (-2.9A)
SAM  A 300 (-3.3A)
 0.52A 3lcvB-3fzgA:
19.9		 3lcvB-3fzgA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5c PROTEIN Z-DEPENDENT
PROTEASE INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		3 ARG A  67
ASP A 298
GLN A  53
 None
 0.76A 3lcvB-3h5cA:
undetectable		 3lcvB-3h5cA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6d PROTOPORPHYRINOGEN
OXIDASE

(Bacillus
subtilis) 		PF01593
(Amino_oxidase) 		3 ARG A 428
ASP A 452
GLN A 192
 None
 0.95A 3lcvB-3i6dA:
undetectable		 3lcvB-3i6dA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icf SERINE/THREONINE-PRO
TEIN PHOSPHATASE T

(Saccharomyces
cerevisiae) 		PF00149
(Metallophos)
PF08321
(PPP5) 		3 ARG A 226
ASP A 314
GLN A 332
 None
 0.69A 3lcvB-3icfA:
undetectable		 3lcvB-3icfA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jx9 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE

(Exiguobacterium
sibiricum) 		PF10740
(DUF2529) 		3 ARG A 141
ASP A 113
GLN A  19
 None
 0.80A 3lcvB-3jx9A:
undetectable		 3lcvB-3jx9A:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lcv SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM

(Micromonospora
zionensis) 		PF07091
(FmrO) 		3 ARG B 108
ASP B 156
GLN B 207
 SAM  B 301 (-3.0A)
SAM  B 301 (-2.9A)
SAM  B 301 (-3.3A)
 0.01A 3lcvB-3lcvB:
46.2		 3lcvB-3lcvB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1u PUTATIVE
GAMMA-D-GLUTAMYL-L-D
IAMINO ACID
ENDOPEPTIDASE

(Desulfovibrio
vulgaris) 		PF00877
(NLPC_P60)
PF12912
(N_NLPC_P60)
PF12913
(SH3_6)
PF12914
(SH3_7) 		3 ARG A 428
ASP A 439
GLN A 403
 None
 0.92A 3lcvB-3m1uA:
undetectable		 3lcvB-3m1uA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ol2 SEMAPHORIN-4D
PLEXIN-B1

(Homo sapiens;
Homo sapiens) 		PF00047
(ig)
PF01403
(Sema)
PF01437
(PSI)
PF01403
(Sema)
PF01437
(PSI) 		3 ARG B 170
ASP B  78
GLN A 344
 None
 0.90A 3lcvB-3ol2B:
undetectable		 3lcvB-3ol2B:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC) 		3 ARG A 651
ASP A 701
GLN A1557
 None
 0.91A 3lcvB-3ptaA:
6.0		 3lcvB-3ptaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qjh 5C.C7 BETA CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG B 208
ASP B 247
GLN B 142
 None
 0.91A 3lcvB-3qjhB:
undetectable		 3lcvB-3qjhB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7w GTP-BINDING PROTEIN
GTR1
GTP-BINDING PROTEIN
GTR2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04670
(Gtr1_RagA)
PF04670
(Gtr1_RagA) 		3 ARG A  37
ASP B 168
GLN B 226
 None
 0.93A 3lcvB-3r7wA:
2.6		 3lcvB-3r7wA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stb SINGLE DOMAIN
ANTIBODY VHH
MP18 RNA EDITING
COMPLEX PROTEIN

(Lama glama;
Trypanosoma
brucei) 		PF07686
(V-set)
PF00436
(SSB) 		3 ARG A  73
ASP A 116
GLN D  46
 None
 0.82A 3lcvB-3stbA:
undetectable		 3lcvB-3stbA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		3 ARG A 393
ASP A 518
GLN A 252
 None
GOL  A 711 ( 3.7A)
GOL  A 720 ( 4.4A)
 0.91A 3lcvB-3ucqA:
undetectable		 3lcvB-3ucqA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ARG A 121
ASP A1061
GLN A1069
 None
 0.95A 3lcvB-3uonA:
undetectable		 3lcvB-3uonA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usz EXO-1,3/1,4-BETA-GLU
CANASE

(Pseudoalteromonas
sp. BB1) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		3 ARG A 268
ASP A 497
GLN A 437
 None
 0.95A 3lcvB-3uszA:
undetectable		 3lcvB-3uszA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzu OUTER MEMBRANE
PROTEIN

(Neisseria
meningitidis) 		PF00267
(Porin_1) 		3 ARG X 203
ASP X 101
GLN X  60
 None
 0.93A 3lcvB-3vzuX:
undetectable		 3lcvB-3vzuX:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aee ALPHA AMYLASE,
CATALYTIC REGION

(Staphylothermus
marinus) 		PF00128
(Alpha-amylase) 		3 ARG A 386
ASP A 579
GLN A 230
 None
 0.93A 3lcvB-4aeeA:
undetectable		 3lcvB-4aeeA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2o YMDB
PHOSPHODIESTERASE

(Bacillus
subtilis) 		PF13277
(YmdB) 		3 ARG A 216
ASP A  71
GLN A 116
 None
 0.89A 3lcvB-4b2oA:
undetectable		 3lcvB-4b2oA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csi CELLULASE

(Humicola grisea) 		PF00840
(Glyco_hydro_7) 		3 ARG A 398
ASP A 258
GLN A 332
 None
 0.78A 3lcvB-4csiA:
undetectable		 3lcvB-4csiA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpf POTASSIUM CHANNEL
SUBFAMILY U MEMBER 1

(Homo sapiens) 		PF03493
(BK_channel_a) 		3 ARG A 960
ASP A 681
GLN A 772
 None
 0.95A 3lcvB-4hpfA:
4.1		 3lcvB-4hpfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htf S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Escherichia
coli) 		PF13847
(Methyltransf_31) 		3 ARG B  26
ASP B  73
GLN B 103
 SO4  B 302 ( 4.1A)
SAM  B 301 (-3.1A)
SAM  B 301 (-3.3A)
 0.86A 3lcvB-4htfB:
10.0		 3lcvB-4htfB:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,NACHT, LRR
AND PYD
DOMAINS-CONTAINING
PROTEIN 1

(Escherichia
coli;
Homo sapiens) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		3 ARG A 415
ASP A 394
GLN A 403
 None
 0.85A 3lcvB-4ifpA:
undetectable		 3lcvB-4ifpA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inq OXYSTEROL-BINDING
PROTEIN HOMOLOG 3

(Saccharomyces
cerevisiae) 		PF01237
(Oxysterol_BP) 		3 ARG A 951
ASP A 925
GLN A 672
 None
 0.78A 3lcvB-4inqA:
undetectable		 3lcvB-4inqA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlw GLUTATHIONE-INDEPEND
ENT FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A 223
ASP A  50
GLN A 338
 NAD  A 403 (-3.4A)
None
NAD  A 403 (-3.8A)
 0.88A 3lcvB-4jlwA:
3.5		 3lcvB-4jlwA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9s GDSL-LIKE
LIPASE/ACYLHYDROLASE
FAMILY PROTEIN

(Neisseria
meningitidis) 		PF00657
(Lipase_GDSL) 		3 ARG A 289
ASP A 279
GLN A 238
 None
 0.79A 3lcvB-4k9sA:
undetectable		 3lcvB-4k9sA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knh NUP192P

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		3 ARG A 658
ASP A 521
GLN A 393
 None
 0.89A 3lcvB-4knhA:
undetectable		 3lcvB-4knhA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 3 ARG A 153
ASP A 140
GLN A  45
 None
 0.84A 3lcvB-4l1yA:
undetectable		 3lcvB-4l1yA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE

(Staphylococcus
aureus) 		PF02423
(OCD_Mu_crystall) 		3 ARG A  94
ASP A 313
GLN A 258
 GOL  A 402 (-4.0A)
None
None
 0.77A 3lcvB-4mp3A:
4.6		 3lcvB-4mp3A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		3 ARG A 265
ASP A 123
GLN A 251
 None
 0.79A 3lcvB-4pfrA:
undetectable		 3lcvB-4pfrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxd ALLANTOATE
AMIDOHYDROLASE

(Escherichia
coli) 		PF01546
(Peptidase_M20) 		3 ARG A 215
ASP A 359
GLN A  40
 1AL  A 502 (-3.9A)
None
None
 0.84A 3lcvB-4pxdA:
undetectable		 3lcvB-4pxdA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG K 308
ASP K 210
GLN K 478
 None
 0.88A 3lcvB-4q66K:
undetectable		 3lcvB-4q66K:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ARG A 200
ASP A 283
GLN A 312
 None
None
FAD  A2001 (-3.6A)
 0.79A 3lcvB-4q73A:
2.7		 3lcvB-4q73A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x3n CALCIUM-REGULATED
ACTIN-BUNDLING
PROTEIN

(Dictyostelium
discoideum) 		no annotation 3 ARG A 198
ASP A  76
GLN A  45
 None
 0.71A 3lcvB-4x3nA:
undetectable		 3lcvB-4x3nA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgt FRQ-INTERACTING RNA
HELICASE

(Neurospora
crassa) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		3 ARG A1063
ASP A 300
GLN A 562
 None
 0.71A 3lcvB-4xgtA:
3.4		 3lcvB-4xgtA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)

(Chaetomium) 		PF13472
(Lipase_GDSL_2) 		3 ARG A 246
ASP A 140
GLN A 320
 None
PEU  A 402 ( 4.2A)
None
 0.88A 3lcvB-4xvhA:
undetectable		 3lcvB-4xvhA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxw C-DOMAIN TYPE II
PEPTIDE SYNTHETASE

(Streptomyces
globisporus) 		PF00668
(Condensation) 		3 ARG A  80
ASP A 402
GLN A 364
 None
 0.91A 3lcvB-4zxwA:
undetectable		 3lcvB-4zxwA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cio PYRROLOQUINOLINE
QUINONE BIOSYNTHESIS
PROTEIN PQQF

(Serratia sp.
FS14) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 ARG A 553
ASP A 136
GLN A 243
 None
 0.90A 3lcvB-5cioA:
undetectable		 3lcvB-5cioA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g26 INTIMIN

(Escherichia
coli) 		PF11924
(IAT_beta) 		3 ARG A 333
ASP A 400
GLN A 367
 None
 0.72A 3lcvB-5g26A:
undetectable		 3lcvB-5g26A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT

(Escherichia
coli;
Escherichia
coli) 		PF00111
(Fer2)
PF01799
(Fer2_2)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		3 ARG C 350
ASP A 154
GLN C 478
 MCN  C 921 ( 3.7A)
None
None
 0.76A 3lcvB-5g5gC:
undetectable		 3lcvB-5g5gC:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy7 PUTATIVE PRE-MRNA
SPLICING PROTEIN

(Chaetomium
thermophilum) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		3 ARG A1208
ASP A  64
GLN A1119
 None
 0.82A 3lcvB-5hy7A:
undetectable		 3lcvB-5hy7A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i47 RIMK DOMAIN PROTEIN
ATP-GRASP

(Sphaerobacter
thermophilus) 		PF08443
(RimK) 		3 ARG A 222
ASP A 241
GLN A 168
 None
 0.91A 3lcvB-5i47A:
undetectable		 3lcvB-5i47A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 ARG A 350
ASP A 481
GLN A1078
 None
MG  A1803 (-3.5A)
None
 0.82A 3lcvB-5ip9A:
undetectable		 3lcvB-5ip9A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A

(Bacteroides
ovatus) 		PF04616
(Glyco_hydro_43) 		3 ARG A 326
ASP A 354
GLN A 393
 None
 0.67A 3lcvB-5jowA:
undetectable		 3lcvB-5jowA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kxj L-ASPARTATE OXIDASE

(Salmonella
enterica) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ARG A 177
ASP A 164
GLN A 471
 None
EDO  A 607 (-3.6A)
None
 0.76A 3lcvB-5kxjA:
undetectable		 3lcvB-5kxjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6v AMYLOSUCRASE

(Neisseria
polysaccharea) 		no annotation 3 ARG A 390
ASP A 507
GLN A 254
 None
None
TRS  A 701 (-4.2A)
 0.95A 3lcvB-5n6vA:
undetectable		 3lcvB-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no8 BACCELL_00875

(Bacteroides
cellulosilyticus) 		no annotation 3 ARG A 445
ASP A 596
GLN A 542
 None
GOL  A 701 (-3.0A)
None
 0.87A 3lcvB-5no8A:
undetectable		 3lcvB-5no8A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM2

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		3 ARG 2 326
ASP 2 435
GLN 2 333
 None
 0.90A 3lcvB-5udb2:
undetectable		 3lcvB-5udb2:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufm METHYLTRANSFERASE
DOMAIN PROTEIN

(Burkholderia
thailandensis) 		no annotation 3 ARG A  79
ASP A  95
GLN A 141
 SAH  A 301 (-2.9A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.2A)
 0.92A 3lcvB-5ufmA:
10.8		 3lcvB-5ufmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqc DIHYDROPYRIMIDINASE-
RELATED PROTEIN 2

(Mus musculus) 		PF01979
(Amidohydro_1) 		3 ARG A 227
ASP A 172
GLN A 180
 None
 0.91A 3lcvB-5uqcA:
undetectable		 3lcvB-5uqcA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w11 GLUCANASE

(Thermothelomyces
thermophila) 		no annotation 3 ARG A 398
ASP A 258
GLN A 332
 CTR  A 506 (-3.5A)
None
None
 0.91A 3lcvB-5w11A:
undetectable		 3lcvB-5w11A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbf UNCONVENTIONAL
MYOSIN-VIIB

(Homo sapiens) 		PF00373
(FERM_M)
PF00784
(MyTH4) 		3 ARG A1770
ASP A1861
GLN A1702
 None
 0.77A 3lcvB-5xbfA:
undetectable		 3lcvB-5xbfA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfo PHD FINGER PROTEIN 1

(Homo sapiens) 		PF00628
(PHD) 		3 ARG A 334
ASP A 177
GLN A 203
 None
 0.87A 3lcvB-5xfoA:
undetectable		 3lcvB-5xfoA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtd NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Homo sapiens) 		PF06212
(GRIM-19) 		3 ARG w 122
ASP w 236
GLN w 215
 None
 0.93A 3lcvB-5xtdw:
undetectable		 3lcvB-5xtdw:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		3 ARG C3467
ASP C3418
GLN C3777
 None
 0.94A 3lcvB-5y3rC:
undetectable		 3lcvB-5y3rC:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT

(Methylobacillus
sp. KY4400;
Methylobacillus
sp. KY4400) 		no annotation
no annotation 		3 ARG C 371
ASP A  99
GLN C 498
 MCN  C 802 (-4.2A)
None
None
 0.74A 3lcvB-5y6qC:
undetectable		 3lcvB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykn PROBABLE
LYSINE-SPECIFIC
DEMETHYLASE JMJ14

(Arabidopsis
thaliana) 		no annotation 3 ARG A 433
ASP A 239
GLN A 116
 None
 0.88A 3lcvB-5yknA:
undetectable		 3lcvB-5yknA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b82 CYTOCHROME P450,
FAMILY 17, SUBFAMILY
A, POLYPEPTIDE 1

(Danio rerio) 		no annotation 3 ARG A 252
ASP A 121
GLN A 235
 None
 0.71A 3lcvB-6b82A:
undetectable		 3lcvB-6b82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4m YERSINOPINE
DEHYDROGENASE

(Yersinia pestis) 		no annotation 3 ARG C 415
ASP C 288
GLN C 335
 None
 0.90A 3lcvB-6c4mC:
undetectable		 3lcvB-6c4mC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn0 16S RRNA
(GUANINE(1405)-N(7))
-METHYLTRANSFERASE

(Proteus
mirabilis) 		no annotation 3 ARG A 111
ASP A 160
GLN A 212
 None
 0.72A 3lcvB-6cn0A:
26.0		 3lcvB-6cn0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE SUBUNIT
BETA
ATP SYNTHASE GAMMA
SUBUNIT
ATP SYNTHASE EPSILON
SUBUNIT

(Trypanosoma
brucei;
Trypanosoma
brucei;
Trypanosoma
brucei) 		no annotation
no annotation
no annotation 		3 ARG G 240
ASP D 399
GLN I  45
 None
 0.93A 3lcvB-6f5dG:
undetectable		 3lcvB-6f5dG:
undetectable