SIMILAR PATTERNS OF AMINO ACIDS FOR 3LB3_B_4CHB192_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a88 CHLOROPEROXIDASE L

(Streptomyces
lividans) 		PF00561
(Abhydrolase_1) 		4 PHE A 202
HIS A  95
THR A  97
VAL A 123
 None
 1.18A 3lb3B-1a88A:
0.0		 3lb3B-1a88A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ci9 PROTEIN
(CARBOXYLESTERASE)

(Burkholderia
gladioli) 		PF00144
(Beta-lactamase) 		4 PHE A 357
TYR A 390
HIS A 342
THR A 345
 None
 1.31A 3lb3B-1ci9A:
0.0		 3lb3B-1ci9A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 PHE B 360
HIS B 377
THR B 383
VAL B 382
 None
 1.26A 3lb3B-1e6vB:
2.1		 3lb3B-1e6vB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jra ERV2 PROTEIN,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF04777
(Evr1_Alr) 		4 PHE A  61
PHE A  22
TYR A  48
VAL A  89
 FAD  A 335 (-3.3A)
None
FAD  A 335 (-4.8A)
None
 1.26A 3lb3B-1jraA:
undetectable		 3lb3B-1jraA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt5 FATTY-ACID AMIDE
HYDROLASE

(Rattus
norvegicus) 		PF01425
(Amidase) 		4 PHE A 182
HIS A 184
THR A 185
VAL A 114
 None
 1.18A 3lb3B-1mt5A:
0.0		 3lb3B-1mt5A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlz PRION PROTEIN

(Homo sapiens) 		PF00377
(Prion) 		4 TYR A 162
HIS A 187
THR A 190
VAL A 189
 None
 1.33A 3lb3B-1qlzA:
1.7		 3lb3B-1qlzA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlm PHOSPHATASE

(Escherichia
coli) 		PF08282
(Hydrolase_3) 		4 PHE A 269
PHE A 230
TYR A 245
VAL A   3
 None
 1.33A 3lb3B-1rlmA:
0.0		 3lb3B-1rlmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sie POLYOMAVIRUS COAT
PROTEIN VP1

(Mus musculus
polyomavirus 1) 		PF00718
(Polyoma_coat) 		4 PHE A 165
PHE A 240
THR A 127
VAL A 125
 None
 1.05A 3lb3B-1sieA:
undetectable		 3lb3B-1sieA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjl DNAK SUPPRESSOR
PROTEIN

(Escherichia
coli) 		PF01258
(zf-dskA_traR) 		4 PHE A  82
HIS A  61
THR A  58
VAL A  59
 None
 1.24A 3lb3B-1tjlA:
1.8		 3lb3B-1tjlA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuo PUTATIVE
PHOSPHOMANNOMUTASE

(Thermus
thermophilus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 PHE A  27
PHE A  64
HIS A  33
THR A  31
 None
 1.24A 3lb3B-1tuoA:
0.0		 3lb3B-1tuoA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xa6 BETA2-CHIMAERIN

(Homo sapiens) 		PF00017
(SH2)
PF00130
(C1_1)
PF00620
(RhoGAP) 		4 PHE A 466
TYR A 398
HIS A 387
VAL A 386
 None
 1.17A 3lb3B-1xa6A:
0.0		 3lb3B-1xa6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xly SHE2P

(Saccharomyces
cerevisiae) 		PF11435
(She2p) 		4 PHE A  92
PHE A 208
THR A  13
VAL A  17
 None
 1.13A 3lb3B-1xlyA:
undetectable		 3lb3B-1xlyA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygu LEUKOCYTE COMMON
ANTIGEN

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 PHE A 816
HIS A 788
THR A 787
VAL A 722
 None
 0.78A 3lb3B-1yguA:
0.0		 3lb3B-1yguA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zoi ESTERASE

(Pseudomonas
putida) 		PF00561
(Abhydrolase_1) 		4 PHE A 203
HIS A  96
THR A  98
VAL A 124
 None
 1.21A 3lb3B-1zoiA:
undetectable		 3lb3B-1zoiA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE

(Pseudomonas sp.
SY-77-1;
Pseudomonas sp.
SY-77-1) 		PF01804
(Penicil_amidase)
PF01804
(Penicil_amidase) 		4 PHE C 438
HIS B  23
THR C 456
VAL C 458
 None
 1.17A 3lb3B-2advC:
undetectable		 3lb3B-2advC:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csg PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF07350
(DUF1479) 		4 PHE A 257
HIS A 239
THR A 241
VAL A 243
 None
 1.03A 3lb3B-2csgA:
undetectable		 3lb3B-2csgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dbr GLYOXYLATE REDUCTASE

(Pyrococcus
horikoshii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 PHE A 278
PHE A 267
TYR A 272
VAL A 283
 None
 1.19A 3lb3B-2dbrA:
undetectable		 3lb3B-2dbrA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dck XYLANASE J

(Bacillus sp.
41M-1) 		PF00457
(Glyco_hydro_11)
PF03422
(CBM_6) 		4 PHE A  94
PHE A 162
HIS A 161
VAL A  83
 None
 1.31A 3lb3B-2dckA:
undetectable		 3lb3B-2dckA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpg GLUCOSE 6-PHOSPHATE
DEHYDROGENASE

(Leuconostoc
mesenteroides) 		PF00479
(G6PD_N)
PF02781
(G6PD_C) 		4 PHE A 284
PHE A 442
TYR A 275
VAL A 334
 None
 1.27A 3lb3B-2dpgA:
undetectable		 3lb3B-2dpgA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewy BETA-SECRETASE 2

(Homo sapiens) 		PF00026
(Asp) 		4 PHE A  68
TYR A  76
THR A 117
VAL A  56
 None
 1.19A 3lb3B-2ewyA:
undetectable		 3lb3B-2ewyA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		4 PHE A1673
TYR A1675
THR A1708
VAL A1712
 None
 1.24A 3lb3B-2ix8A:
undetectable		 3lb3B-2ix8A:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1

(Mus musculus) 		PF04099
(Sybindin) 		4 PHE C  61
PHE C  64
HIS C  72
VAL C  83
 None
 0.95A 3lb3B-2j3tC:
undetectable		 3lb3B-2j3tC:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE

(Escherichia
coli) 		PF01204
(Trehalase) 		4 PHE A 480
TYR A 498
THR A 525
VAL A 524
 None
 1.25A 3lb3B-2jf4A:
undetectable		 3lb3B-2jf4A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5r GLUTAMYL-TRNA
SYNTHETASE 1

(Thermotoga
maritima) 		PF00749
(tRNA-synt_1c) 		4 PHE A 430
PHE A 395
HIS A 423
VAL A 425
 None
 1.31A 3lb3B-2o5rA:
undetectable		 3lb3B-2o5rA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8q CLASS I
PHOSPHODIESTERASE
PDEB1

(Leishmania
major) 		PF00233
(PDEase_I) 		4 PHE A 899
TYR A 696
THR A 840
VAL A 839
 None
 1.05A 3lb3B-2r8qA:
undetectable		 3lb3B-2r8qA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9i RHAMNULOSE-1-PHOSPHA
TE ALDOLASE

(Escherichia
coli) 		PF00596
(Aldolase_II) 		4 PHE A  70
PHE A 122
HIS A 121
VAL A  72
 None
 1.25A 3lb3B-2v9iA:
undetectable		 3lb3B-2v9iA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w7z PENTAPEPTIDE REPEAT
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF13599
(Pentapeptide_4) 		4 PHE A 104
PHE A  94
THR A 102
VAL A  82
 None
 1.21A 3lb3B-2w7zA:
undetectable		 3lb3B-2w7zA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06460
(NSP13) 		4 TYR A 152
HIS A 119
THR A 120
VAL A 290
 None
 1.25A 3lb3B-2xyqA:
undetectable		 3lb3B-2xyqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zl5 58 KD CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 PHE A 352
PHE A 320
THR A 347
VAL A 345
 None
None
ACT  A 521 ( 4.5A)
None
 1.25A 3lb3B-2zl5A:
undetectable		 3lb3B-2zl5A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anx SPERMIDINE SYNTHASE

(Thermus
thermophilus) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 PHE A  43
PHE A 231
THR A  56
VAL A  46
 None
 1.03A 3lb3B-3anxA:
undetectable		 3lb3B-3anxA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asp CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 PHE A 360
PHE A 323
THR A 355
VAL A 353
 None
 1.30A 3lb3B-3aspA:
undetectable		 3lb3B-3aspA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf5 RIBOKINASE RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF00294
(PfkB) 		4 PHE A 180
TYR A 177
THR A 193
VAL A 191
 None
 1.33A 3lb3B-3bf5A:
undetectable		 3lb3B-3bf5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE

(Toxoplasma
gondii) 		PF00160
(Pro_isomerase) 		4 PHE A  43
PHE A 119
THR A  46
VAL A 166
 None
 1.22A 3lb3B-3bo7A:
undetectable		 3lb3B-3bo7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwq CAPSID PROTEIN VP1

(Macaca mulatta
polyomavirus 1) 		PF00718
(Polyoma_coat) 		4 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.21A 3lb3B-3bwqA:
undetectable		 3lb3B-3bwqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec3 PROTEIN
DISULFIDE-ISOMERASE
A4

(Rattus
norvegicus) 		PF13848
(Thioredoxin_6) 		4 PHE A 334
TYR A 321
HIS A 335
VAL A 304
 None
 1.23A 3lb3B-3ec3A:
undetectable		 3lb3B-3ec3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Streptococcus
agalactiae) 		PF01408
(GFO_IDH_MocA) 		4 PHE A 100
PHE A 111
THR A 101
VAL A 309
 None
 1.21A 3lb3B-3evnA:
undetectable		 3lb3B-3evnA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7q INTEGRIN BETA-4

(Homo sapiens) 		PF00041
(fn3) 		4 PHE A1228
TYR A1296
THR A1236
VAL A1230
 None
 1.32A 3lb3B-3f7qA:
undetectable		 3lb3B-3f7qA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fe1 HEAT SHOCK 70 KDA
PROTEIN 6

(Homo sapiens) 		PF00012
(HSP70) 		4 PHE A 200
PHE A 207
THR A 343
VAL A 348
 None
 1.33A 3lb3B-3fe1A:
undetectable		 3lb3B-3fe1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flj UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA WITH A
CYSTATIN-LIKE FOLD

(Ruegeria
pomeroyi) 		PF12680
(SnoaL_2) 		4 PHE A  59
PHE A  75
TYR A  61
VAL A  52
 UNL  A 137 (-4.5A)
UNL  A 137 ( 4.4A)
None
UNL  A 137 ( 4.9A)
 1.22A 3lb3B-3fljA:
undetectable		 3lb3B-3fljA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)

(Bacteroides
thetaiotaomicron) 		PF08842
(Mfa2) 		4 PHE A 292
PHE A 175
HIS A 289
VAL A 305
 None
None
EDO  A   1 ( 4.7A)
None
 1.29A 3lb3B-3gf8A:
undetectable		 3lb3B-3gf8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gl1 HEAT SHOCK PROTEIN
SSB1

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 PHE A 201
PHE A 208
THR A 344
VAL A 349
 None
 1.33A 3lb3B-3gl1A:
undetectable		 3lb3B-3gl1A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyr PHENOXAZINONE
SYNTHASE

(Streptomyces
antibioticus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 189
HIS A 161
THR A 160
VAL A 159
 None
CU  A1004 ( 3.2A)
None
None
 1.06A 3lb3B-3gyrA:
undetectable		 3lb3B-3gyrA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilr HEPARIN LYASE I

(Bacteroides
thetaiotaomicron) 		PF14099
(Polysacc_lyase) 		4 PHE A 174
PHE A 183
THR A 157
VAL A 159
 None
 1.10A 3lb3B-3ilrA:
undetectable		 3lb3B-3ilrA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki6 CHOLIX TOXIN

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly) 		4 PHE A 541
TYR A 626
THR A 496
VAL A 494
 None
 1.29A 3lb3B-3ki6A:
undetectable		 3lb3B-3ki6A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksu 3-OXOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Oenococcus oeni) 		PF13561
(adh_short_C2) 		4 PHE A  80
PHE A 127
HIS A  39
VAL A  37
 None
 1.06A 3lb3B-3ksuA:
undetectable		 3lb3B-3ksuA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lu2 LMO2462 PROTEIN

(Listeria
monocytogenes) 		PF01244
(Peptidase_M19) 		4 PHE A 224
PHE A 281
TYR A 278
VAL A 222
 None
 1.09A 3lb3B-3lu2A:
undetectable		 3lb3B-3lu2A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na6 SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Ruegeria sp.
TM1040) 		PF04952
(AstE_AspA) 		4 PHE A  90
TYR A 194
THR A  54
VAL A  87
 None
 1.10A 3lb3B-3na6A:
undetectable		 3lb3B-3na6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Clostridium
perfringens) 		PF14010
(PEPcase_2) 		4 PHE A 269
PHE A 249
HIS A 277
THR A 282
 None
 1.31A 3lb3B-3odmA:
undetectable		 3lb3B-3odmA:
13.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3oj1 DEHALOPEROXIDASE A

(Amphitrite
ornata) 		PF00042
(Globin) 		5 PHE A  21
PHE A  35
TYR A  38
THR A  56
VAL A  59
 None
HEM  A 139 (-3.9A)
None
None
HEM  A 139 (-3.8A)
 0.88A 3lb3B-3oj1A:
27.0		 3lb3B-3oj1A:
99.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q87 PUTATIVE
UNCHARACTERIZED
PROTEIN ECU08_1170

(Encephalitozoon
cuniculi) 		PF03966
(Trm112p) 		4 PHE A  76
PHE A  40
HIS A  43
THR A  46
 None
 1.26A 3lb3B-3q87A:
undetectable		 3lb3B-3q87A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r24 2'-O-METHYL
TRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06460
(NSP13) 		4 TYR A 152
HIS A 119
THR A 120
VAL A 290
 None
 1.17A 3lb3B-3r24A:
undetectable		 3lb3B-3r24A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sz6 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis) 		PF05031
(NEAT) 		4 PHE A  87
PHE A 144
THR A  98
VAL A 112
 None
 1.08A 3lb3B-3sz6A:
undetectable		 3lb3B-3sz6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3teo CARBON DISULFIDE
HYDROLASE

(Acidianus sp.
A1-3) 		PF00484
(Pro_CA) 		4 TYR A 139
HIS A  88
THR A  87
VAL A 174
 None
CL  A 205 (-4.6A)
None
None
 1.03A 3lb3B-3teoA:
undetectable		 3lb3B-3teoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufk UNDA

(Shewanella sp.
HRCR_06) 		PF13435
(Cytochrome_C554) 		4 PHE A 511
TYR A 565
HIS A 503
VAL A 508
 None
 1.15A 3lb3B-3ufkA:
undetectable		 3lb3B-3ufkA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9y DISKS LARGE HOMOLOG
1

(Homo sapiens) 		PF00625
(Guanylate_kin) 		4 PHE A 800
HIS A 783
THR A 768
VAL A 785
 None
 1.26A 3lb3B-3w9yA:
undetectable		 3lb3B-3w9yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnp CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Bacillus
circulans) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 TYR A 601
HIS A 567
THR A 566
VAL A 408
 None
 0.82A 3lb3B-3wnpA:
undetectable		 3lb3B-3wnpA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 PHE A 267
PHE A 459
THR A 295
VAL A 297
 None
 1.23A 3lb3B-4b9yA:
undetectable		 3lb3B-4b9yA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cd8 ENDO-BETA-1,4-MANNAN
ASE

(Alicyclobacillus
acidocaldarius) 		no annotation 4 PHE A 275
PHE A 229
TYR A 278
VAL A 213
 None
 1.32A 3lb3B-4cd8A:
undetectable		 3lb3B-4cd8A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dgq NON-HEME
CHLOROPEROXIDASE

(Burkholderia
cenocepacia) 		PF00561
(Abhydrolase_1) 		4 PHE A 203
HIS A  96
THR A  98
VAL A 124
 EDO  A 301 ( 3.7A)
None
EDO  A 301 (-3.7A)
None
 1.21A 3lb3B-4dgqA:
undetectable		 3lb3B-4dgqA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dj3 PERIOD CIRCADIAN
PROTEIN HOMOLOG 3

(Mus musculus) 		PF08447
(PAS_3) 		4 PHE A 280
PHE A 338
THR A 272
VAL A 283
 None
 1.23A 3lb3B-4dj3A:
undetectable		 3lb3B-4dj3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw8 BACTERIAL
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, PUTATIVE

(Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		4 PHE A 197
PHE A 205
TYR A 201
VAL A 378
 None
 1.24A 3lb3B-4hw8A:
undetectable		 3lb3B-4hw8A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgs MLV-RELATED PROVIRAL
ENV POLYPROTEIN

(Mus musculus) 		PF00429
(TLV_coat) 		4 TYR A 540
HIS A 543
THR A 544
VAL A 547
 None
 1.18A 3lb3B-4jgsA:
undetectable		 3lb3B-4jgsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq7 HYPOTHETICAL PROTEIN

(Bacteroides
uniformis) 		PF11175
(DUF2961) 		4 PHE A 299
HIS A 330
THR A 329
VAL A 265
 None
 1.11A 3lb3B-4kq7A:
undetectable		 3lb3B-4kq7A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lbw ELONGATION FACTOR
TU-A

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 PHE A 344
PHE A 316
HIS A 313
VAL A 378
 None
 1.27A 3lb3B-4lbwA:
undetectable		 3lb3B-4lbwA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mj0 VP1 CAPSID PROTEIN

(Human
polyomavirus 1) 		PF00718
(Polyoma_coat) 		4 PHE A 152
PHE A 221
THR A 117
VAL A 115
 None
 1.26A 3lb3B-4mj0A:
undetectable		 3lb3B-4mj0A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Chromohalobacter
salexigens) 		PF03480
(DctP) 		4 PHE A 125
PHE A 115
TYR A 240
HIS A 122
 None
 1.30A 3lb3B-4n8gA:
undetectable		 3lb3B-4n8gA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4np4 TOXIN B

(Clostridioides
difficile) 		PF01473
(CW_binding_1) 		4 PHE A1888
PHE A1856
TYR A1865
THR A1879
 None
 1.29A 3lb3B-4np4A:
undetectable		 3lb3B-4np4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nv4 SIGNAL PEPTIDASE I

(Bacillus
anthracis) 		PF00717
(Peptidase_S24) 		4 PHE A 143
PHE A 126
HIS A 157
VAL A 145
 None
None
PG4  A 201 (-3.9A)
None
 1.14A 3lb3B-4nv4A:
undetectable		 3lb3B-4nv4A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ojz PUTATIVE ALGINATE
LYASE

(Saccharophagus
degradans) 		PF05426
(Alginate_lyase)
PF07940
(Hepar_II_III) 		4 PHE A 266
TYR A 252
HIS A 200
THR A 204
 None
None
LGU  A 802 ( 4.2A)
None
 1.19A 3lb3B-4ojzA:
undetectable		 3lb3B-4ojzA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)

(Mycobacterium
tuberculosis) 		PF14021
(TNT) 		4 PHE B 671
PHE B 696
TYR B 710
THR B 785
 None
 1.09A 3lb3B-4qlpB:
undetectable		 3lb3B-4qlpB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D

(Homo sapiens) 		PF12706
(Lactamase_B_2) 		4 PHE A 246
PHE A 144
HIS A 241
VAL A 244
 None
 1.29A 3lb3B-4qn9A:
undetectable		 3lb3B-4qn9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qny MITOGEN ACTIVATED
PROTEIN KINASE,
PUTATIVE

(Leishmania
donovani) 		PF00069
(Pkinase) 		4 PHE A  58
PHE A  97
HIS A  99
VAL A  53
 None
 1.14A 3lb3B-4qnyA:
1.2		 3lb3B-4qnyA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsi MAGUK P55 SUBFAMILY
MEMBER 5

(Homo sapiens) 		PF00595
(PDZ)
PF00625
(Guanylate_kin)
PF07653
(SH3_2) 		4 PHE A 536
PHE A 545
THR A 515
VAL A 531
 None
 1.33A 3lb3B-4wsiA:
undetectable		 3lb3B-4wsiA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
GAMMA

(Methanothermobacter
marburgensis) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 PHE B 359
HIS B 376
THR B 382
VAL B 381
 None
 1.22A 3lb3B-5a8rB:
undetectable		 3lb3B-5a8rB:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aov GLYOXYLATE REDUCTASE

(Pyrococcus
furiosus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 PHE A 278
PHE A 267
TYR A 272
VAL A 283
 None
None
1PE  A1355 (-4.4A)
None
 1.16A 3lb3B-5aovA:
undetectable		 3lb3B-5aovA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b8i SERINE/THREONINE-PRO
TEIN PHOSPHATASE

(Coccidioides
immitis) 		PF00149
(Metallophos) 		4 PHE A 133
PHE A 120
TYR A 131
VAL A 109
 None
 1.33A 3lb3B-5b8iA:
undetectable		 3lb3B-5b8iA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chv UBL
CARBOXYL-TERMINAL
HYDROLASE 18

(Mus musculus) 		PF00443
(UCH) 		4 PHE A 165
PHE A  70
THR A 247
VAL A 362
 None
 1.31A 3lb3B-5chvA:
undetectable		 3lb3B-5chvA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1x D4-30 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B

(Homo sapiens;
Staphylococcus
aureus) 		PF07654
(C1-set)
PF07686
(V-set)
PF05031
(NEAT) 		4 PHE B  54
PHE E 366
TYR E 391
HIS B  32
 None
 1.22A 3lb3B-5d1xB:
undetectable		 3lb3B-5d1xB:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF04422
(FrhB_FdhB_N)
PF04432
(FrhB_FdhB_C) 		4 PHE A 247
PHE A 263
TYR A 261
VAL A 294
 None
 1.18A 3lb3B-5dqrA:
undetectable		 3lb3B-5dqrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3t PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE I,
ALPHA

(Danio rerio) 		PF01504
(PIP5K) 		4 PHE A 116
HIS A  72
THR A  71
VAL A  74
 None
 1.03A 3lb3B-5e3tA:
1.1		 3lb3B-5e3tA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k6o B-GLUCOSIDASE

(metagenome) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 PHE A 357
PHE A 399
THR A 297
VAL A 355
 None
 1.25A 3lb3B-5k6oA:
undetectable		 3lb3B-5k6oA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kay SPELTER

(unidentified) 		PF00669
(Flagellin_N) 		4 PHE A 131
PHE A  87
HIS A 125
VAL A 194
 None
None
ZN  A 301 (-3.1A)
None
 1.20A 3lb3B-5kayA:
undetectable		 3lb3B-5kayA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kci UNCHARACTERIZED
PROTEIN YPL067C

(Saccharomyces
cerevisiae) 		PF12239
(DUF3605) 		4 PHE A 173
TYR A 178
HIS A 148
VAL A 149
 None
 1.29A 3lb3B-5kciA:
undetectable		 3lb3B-5kciA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2d SURFACE-ASSOCIATED
PROTEIN CSHA

(Streptococcus
gordonii) 		no annotation 4 PHE A  19
PHE A   4
THR A  23
VAL A  39
 None
 1.18A 3lb3B-5l2dA:
undetectable		 3lb3B-5l2dA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0j SWI5-DEPENDENT HO
EXPRESSION PROTEIN
2,SWI5-DEPENDENT HO
EXPRESSION PROTEIN 3

(Saccharomyces
cerevisiae) 		no annotation 4 PHE D  92
PHE D 208
THR D  13
VAL D  17
 None
 1.17A 3lb3B-5m0jD:
undetectable		 3lb3B-5m0jD:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PUTATIVE PRE-MRNA
SPLICING FACTOR

(Chaetomium
thermophilum) 		PF08084
(PROCT) 		4 PHE B2087
HIS B2152
THR B2153
VAL B2190
 None
 1.25A 3lb3B-5m59B:
undetectable		 3lb3B-5m59B:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz9 -

(-) 		no annotation 4 PHE A  43
PHE A 904
TYR A 910
THR A  41
 None
 1.13A 3lb3B-5mz9A:
undetectable		 3lb3B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE

(Homo sapiens) 		no annotation 4 PHE A 240
PHE A 129
TYR A 133
THR A 158
 None
 1.18A 3lb3B-5nn8A:
0.0		 3lb3B-5nn8A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nrg 50S RIBOSOMAL
PROTEIN L25

(Staphylococcus
aureus) 		PF01386
(Ribosomal_L25p)
PF14693
(Ribosomal_TL5_C) 		4 PHE S  48
PHE S  91
HIS S  88
VAL S  27
 None
None
G  Y  74 ( 3.8A)
None
 1.29A 3lb3B-5nrgS:
undetectable		 3lb3B-5nrgS:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opg ENVELOPE
GLYCOPROTEIN GN

(Hantaan
orthohantavirus) 		PF01567
(Hanta_G1) 		4 PHE A 223
PHE A 274
THR A 329
VAL A 241
 None
 1.32A 3lb3B-5opgA:
undetectable		 3lb3B-5opgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 4 PHE A 644
HIS A 619
THR A 622
VAL A 618
 None
 1.15A 3lb3B-5opqA:
undetectable		 3lb3B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tkf LYTIC POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 PHE A   4
HIS A 134
THR A  62
VAL A  61
 None
 1.22A 3lb3B-5tkfA:
undetectable		 3lb3B-5tkfA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uft NITROGEN-FIXING
NIFU-LIKE,
N-TERMINAL

(Brucella
abortus) 		PF01592
(NifU_N) 		4 PHE A 129
PHE A 106
THR A 128
VAL A 132
 None
 1.28A 3lb3B-5uftA:
undetectable		 3lb3B-5uftA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1m U6 SNRNA
PHOSPHODIESTERASE

(Homo sapiens) 		PF09749
(HVSL) 		4 PHE A 137
HIS A  84
THR A  83
VAL A 127
 None
GOL  A 303 (-3.4A)
None
None
 0.72A 3lb3B-5v1mA:
undetectable		 3lb3B-5v1mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF04084
(ORC2) 		4 PHE B 316
PHE B 325
HIS B 425
VAL B 453
 None
 1.27A 3lb3B-5v8fB:
undetectable		 3lb3B-5v8fB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu7 UNCHARACTERIZED
PROTEIN

(Pyrococcus
horikoshii) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 PHE A 329
PHE A   7
TYR A 354
VAL A 333
 None
 1.27A 3lb3B-5wu7A:
undetectable		 3lb3B-5wu7A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Paenibacillus
sp. 598K) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 TYR A 602
HIS A 568
THR A 567
VAL A 409
 None
 0.76A 3lb3B-5x7hA:
undetectable		 3lb3B-5x7hA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dw1 -

(-) 		no annotation 4 PHE C 216
HIS C 215
THR C 196
VAL C 197
 None
 1.18A 3lb3B-6dw1C:
undetectable		 3lb3B-6dw1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6esb CAPSID PROTEIN VP1

(Human
polyomavirus 1) 		no annotation 4 PHE 1 152
PHE 1 221
THR 1 117
VAL 1 115
 None
 1.26A 3lb3B-6esb1:
undetectable		 3lb3B-6esb1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhe -

(-) 		no annotation 4 PHE A  47
PHE A 326
HIS A  39
THR A  43
 None
 1.32A 3lb3B-6fheA:
undetectable		 3lb3B-6fheA:
undetectable