SIMILAR PATTERNS OF AMINO ACIDS FOR 3KVV_A_URFA254_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | GLY A 708GLN A 339ARG A 471ILE A 457 | B12 A 800 ( 4.4A)NoneNoneNone | 1.14A | 3kvvA-1e1cA:undetectable | 3kvvA-1e1cA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0y | INTERLEUKIN-1RECEPTOR, TYPE I (Homo sapiens) |
PF07679(I-set)PF13895(Ig_2) | 4 | GLY R 121GLN R 113ILE R 165VAL R 166 | None | 0.99A | 3kvvA-1g0yR:undetectable | 3kvvA-1g0yR:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o4s | ASPARTATEAMINOTRANSFERASE (Thermotogamaritima) |
PF00155(Aminotran_1_2) | 4 | GLY A 244MET A 238ILE A 267VAL A 94 | None | 0.88A | 3kvvA-1o4sA:undetectable | 3kvvA-1o4sA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,DELTA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 4 | GLY C 301MET C 293ILE C 303VAL C 304 | None | 0.92A | 3kvvA-1oedC:undetectable | 3kvvA-1oedC:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q3x | MANNAN-BINDINGLECTIN SERINEPROTEASE 2 (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 4 | GLY A 634GLN A 459ILE A 652VAL A 653 | NoneNoneNoneGOL A 701 (-4.9A) | 1.14A | 3kvvA-1q3xA:undetectable | 3kvvA-1q3xA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu7 | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN I (Escherichiacoli) |
PF00015(MCPsignal) | 4 | GLY A 370GLN A 374ILE A 368VAL A 367 | None | 1.09A | 3kvvA-1qu7A:undetectable | 3kvvA-1qu7A:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6m | RIBONUCLEASE PH (Pseudomonasaeruginosa) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | GLY A 133GLN A 233MET A 159VAL A 29 | None | 1.08A | 3kvvA-1r6mA:undetectable | 3kvvA-1r6mA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1raj | GENOME POLYPROTEIN (Enterovirus C) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 306ILE A 324 | None | 1.17A | 3kvvA-1rajA:undetectable | 3kvvA-1rajA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rdr | POLIOVIRUS 3DPOLYMERASE (Enterovirus C) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 306ILE A 324 | None | 1.06A | 3kvvA-1rdrA:undetectable | 3kvvA-1rdrA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb3 | 4-HYDROXYBENZOYL-COAREDUCTASE ALPHASUBUNIT4-HYDROXYBENZOYL-COAREDUCTASE GAMMASUBUNIT (Thaueraaromatica) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 4 | GLY C 139GLN C 99ILE A 705VAL C 141 | NonePCD A1920 ( 4.0A)NoneNone | 1.14A | 3kvvA-1sb3C:undetectable | 3kvvA-1sb3C:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t0i | YLR011WP (Saccharomycescerevisiae) |
PF03358(FMN_red) | 4 | GLY A 126GLN A 94ILE A 155VAL A 157 | FMN A 200 (-3.7A)FMN A 200 (-3.9A)NoneFMN A 200 (-4.4A) | 1.08A | 3kvvA-1t0iA:3.0 | 3kvvA-1t0iA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tp7 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 305ILE A 323 | None | 1.11A | 3kvvA-1tp7A:undetectable | 3kvvA-1tp7A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u08 | HYPOTHETICALAMINOTRANSFERASEYBDL (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | GLY A 346GLN A 385ILE A 33VAL A 347 | None | 1.08A | 3kvvA-1u08A:undetectable | 3kvvA-1u08A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uou | THYMIDINEPHOSPHORYLASE (Homo sapiens) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | GLY A 186ARG A 146ILE A 167VAL A 166 | None | 1.11A | 3kvvA-1uouA:3.9 | 3kvvA-1uouA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us4 | PUTATIVE GLUR0LIGAND BINDING CORE (Thermusthermophilus) |
PF16868(NMT1_3) | 4 | GLY A 172GLN A 174ILE A 165VAL A 167 | None | 1.04A | 3kvvA-1us4A:undetectable | 3kvvA-1us4A:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vr9 | CBS DOMAINPROTEIN/ACT DOMAINPROTEIN (Thermotogamaritima) |
PF00571(CBS) | 4 | GLY A 46MET A 101ILE A 36VAL A 47 | None | 1.07A | 3kvvA-1vr9A:undetectable | 3kvvA-1vr9A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wol | 122AA LONG CONSERVEDHYPOTHETICAL PROTEIN (Sulfurisphaeratokodaii) |
PF05168(HEPN) | 4 | GLY A 44GLN A 49ILE A 8VAL A 4 | None | 1.04A | 3kvvA-1wolA:undetectable | 3kvvA-1wolA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr8 | PHOSPHOGLYCOLATEPHOSPHATASE (Pyrococcushorikoshii) |
PF08282(Hydrolase_3) | 4 | GLY A 176GLN A 196ILE A 8VAL A 175 | None | 1.07A | 3kvvA-1wr8A:3.5 | 3kvvA-1wr8A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr6 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 305ILE A 323 | None | 0.98A | 3kvvA-1xr6A:undetectable | 3kvvA-1xr6A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aip | PROTEIN C ACTIVATOR (Agkistrodoncontortrix) |
PF00089(Trypsin) | 4 | GLY A 211MET A 139ILE A 212VAL A 231 | None | 1.15A | 3kvvA-2aipA:undetectable | 3kvvA-2aipA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyy | V-CRK SARCOMA VIRUSCT10 ONCOGENEHOMOLOG ISOFORM A (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 4 | GLY A 126GLN A 123ILE A 128VAL A 127 | None | 1.05A | 3kvvA-2eyyA:undetectable | 3kvvA-2eyyA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gxa | REPLICATION PROTEINE1 (Deltapapillomavirus4) |
PF00519(PPV_E1_C) | 4 | GLN A 374ARG A 370ILE A 503VAL A 511 | None | 1.05A | 3kvvA-2gxaA:undetectable | 3kvvA-2gxaA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ijd | PICORNAIN 3C,RNA-DIRECTED RNAPOLYMERASE (Enterovirus C) |
PF00548(Peptidase_C3)PF00680(RdRP_1) | 4 | GLY 1 390GLN 1 267ARG 1 489ILE 1 507 | None | 1.01A | 3kvvA-2ijd1:undetectable | 3kvvA-2ijd1:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j5t | GLUTAMATE 5-KINASE (Escherichiacoli) |
PF00696(AA_kinase)PF01472(PUA) | 4 | GLY A 243GLN A 34ILE A 249VAL A 245 | None | 1.15A | 3kvvA-2j5tA:undetectable | 3kvvA-2j5tA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00698(Acyl_transf_1)PF16197(KAsynt_C_assoc) | 4 | GLY A 579MET A 499ILE A 495VAL A 578 | None | 1.13A | 3kvvA-2jfdA:undetectable | 3kvvA-2jfdA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mx6 | SEGMENT POLARITYPROTEIN DISHEVELLEDHOMOLOG DVL-1 (Mus musculus) |
PF00595(PDZ) | 4 | GLY A 281MET A 284ILE A 266VAL A 267 | None | 0.96A | 3kvvA-2mx6A:undetectable | 3kvvA-2mx6A:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nbg | TRANSLATIONINITIATION FACTORIF-2 (Geobacillusstearothermophilus) |
no annotation | 4 | GLY A 447MET A 400ILE A 450VAL A 459 | None | 1.17A | 3kvvA-2nbgA:undetectable | 3kvvA-2nbgA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oce | HYPOTHETICAL PROTEINPA5201 (Pseudomonasaeruginosa) |
PF00575(S1)PF09371(Tex_N)PF12836(HHH_3)PF16921(Tex_YqgF) | 4 | GLY A 660GLN A 643ILE A 704VAL A 661 | None | 0.97A | 3kvvA-2oceA:undetectable | 3kvvA-2oceA:16.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | GLY A1096GLN A1166ARG A1168MET A1197 | None | 0.70A | 3kvvA-2oxfA:43.8 | 3kvvA-2oxfA:97.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | GLY A1096GLN A1166MET A1197VAL A1221 | None | 0.78A | 3kvvA-2oxfA:43.8 | 3kvvA-2oxfA:97.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbi | REGULATOR OFG-PROTEIN SIGNALING9 (Mus musculus) |
PF00610(DEP)PF00615(RGS)PF00631(G-gamma) | 4 | GLY A 74GLN A 71ILE A 83VAL A 78 | None | 1.10A | 3kvvA-2pbiA:undetectable | 3kvvA-2pbiA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqp | LARGE CAPSID PROTEIN (Providencevirus) |
PF03566(Peptidase_A21) | 4 | GLY A 549MET A 445ILE A 440VAL A 550 | None | 1.03A | 3kvvA-2qqpA:undetectable | 3kvvA-2qqpA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqp | SMALL CAPSID PROTEIN (Providencevirus) |
PF03566(Peptidase_A21) | 4 | GLY B 584GLN B 588ILE B 582VAL B 581 | None | 1.14A | 3kvvA-2qqpB:undetectable | 3kvvA-2qqpB:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qy0 | COMPLEMENT C1RSUBCOMPONENT (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY B 638GLN B 461ILE B 656VAL B 657 | None | 1.14A | 3kvvA-2qy0B:undetectable | 3kvvA-2qy0B:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9p | REPLICATION PROTEINE1 (Deltapapillomavirus4) |
PF00519(PPV_E1_C) | 4 | GLN A 374ARG A 370ILE A 503VAL A 511 | None | 0.91A | 3kvvA-2v9pA:undetectable | 3kvvA-2v9pA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhe | UNC18 (Monosigabrevicollis) |
PF00995(Sec1) | 4 | GLN A 199ARG A 500ILE A 211VAL A 206 | None | 1.01A | 3kvvA-2xheA:undetectable | 3kvvA-2xheA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg6 | PUTRESCINE OXIDASE (Rhodococcuserythropolis) |
PF01593(Amino_oxidase) | 4 | GLY A 435GLN A 65ILE A 15VAL A 437 | NoneFAD A 600 ( 4.5A)NoneNone | 1.13A | 3kvvA-2yg6A:undetectable | 3kvvA-2yg6A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5x | AMINE OXIDASE[FLAVIN-CONTAINING]A (Homo sapiens) |
PF01593(Amino_oxidase) | 4 | GLY A 447GLN A 74ILE A 23VAL A 449 | NoneFAD A 600 ( 4.7A)FAD A 600 (-4.9A)None | 1.09A | 3kvvA-2z5xA:undetectable | 3kvvA-2z5xA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1i | AMIDASE (Rhodococcus sp.N-771) |
PF01425(Amidase) | 4 | GLY A 137MET A 106ILE A 80VAL A 135 | None | 1.04A | 3kvvA-3a1iA:undetectable | 3kvvA-3a1iA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ada | SARCOSINE OXIDASEBETA SUBUNIT (Corynebacteriumsp. U-96) |
PF01266(DAO) | 4 | GLY B 28MET B 61ILE B 190VAL B 50 | FAD B 1 ( 4.8A)FAD B 1 (-3.8A)NoneNone | 1.11A | 3kvvA-3adaB:undetectable | 3kvvA-3adaB:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bje | NUCLEOSIDEPHOSPHORYLASE,PUTATIVE (Trypanosomabrucei) |
PF01048(PNP_UDP_1) | 4 | GLY A 142GLN A 246ARG A 248MET A 285 | URA A 501 (-3.4A)URA A 501 (-3.0A)URA A 501 (-2.9A)R1P A 401 ( 3.9A) | 0.20A | 3kvvA-3bjeA:30.5 | 3kvvA-3bjeA:25.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctz | XAA-PROAMINOPEPTIDASE 1 (Homo sapiens) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 4 | GLY A 492GLN A 419ILE A 519VAL A 491 | None | 1.09A | 3kvvA-3ctzA:undetectable | 3kvvA-3ctzA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epj | TRNAISOPENTENYLTRANSFERASE (Saccharomycescerevisiae) |
PF01715(IPPT) | 4 | GLY A 110GLN A 49MET A 74ILE A 19 | None | 1.11A | 3kvvA-3epjA:2.8 | 3kvvA-3epjA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euf | URIDINEPHOSPHORYLASE 1 (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | GLY A 143GLN A 217ARG A 219MET A 249 | BAU A 400 (-3.3A)BAU A 400 (-3.1A)BAU A 400 (-3.0A)BAU A 400 (-3.8A) | 0.23A | 3kvvA-3eufA:25.8 | 3kvvA-3eufA:27.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flb | RIFR (Amycolatopsismediterranei) |
PF00975(Thioesterase) | 4 | GLY A 56GLN A 53ILE A 170VAL A 166 | None | 1.07A | 3kvvA-3flbA:undetectable | 3kvvA-3flbA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdo | UNCHARACTERIZEDOXIDOREDUCTASE YVAA (Bacillussubtilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 237MET A 209ILE A 239VAL A 240 | None | 0.93A | 3kvvA-3gdoA:undetectable | 3kvvA-3gdoA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gpi | NAD-DEPENDENTEPIMERASE/DEHYDRATASE (Methylobacillusflagellatus) |
PF13460(NAD_binding_10) | 4 | GLY A 8GLN A 35ARG A 32VAL A 69 | None | 1.07A | 3kvvA-3gpiA:2.7 | 3kvvA-3gpiA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h95 | NUCLEOSIDEDIPHOSPHATE-LINKEDMOIETY X MOTIF 6 (Homo sapiens) |
PF00293(NUDIX) | 4 | GLY A 145GLN A 143ILE A 225VAL A 146 | None | 0.96A | 3kvvA-3h95A:undetectable | 3kvvA-3h95A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhs | PHENOLOXIDASESUBUNIT 1 (Manduca sexta) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | GLY B 244GLN B 257MET B 251ILE B 526 | None | 1.12A | 3kvvA-3hhsB:undetectable | 3kvvA-3hhsB:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvy | URIDINEPHOSPHORYLASE (Bos taurus) |
PF01048(PNP_UDP_1) | 4 | GLY A 142GLN A 216ARG A 218MET A 248 | URA A 312 (-3.3A)URA A 312 (-3.3A)URA A 312 (-2.9A)URA A 312 ( 3.7A) | 0.25A | 3kvvA-3kvyA:26.0 | 3kvvA-3kvyA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5m | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE (Bacillusanthracis) |
PF00202(Aminotran_3) | 4 | GLY A 224GLN A 159ARG A 162ILE A 255 | None | 1.17A | 3kvvA-3n5mA:undetectable | 3kvvA-3n5mA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obz | PHYTANOYL-COADIOXYGENASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF05721(PhyH) | 4 | GLY A 37GLN A 258ILE A 39VAL A 40 | None | 1.01A | 3kvvA-3obzA:undetectable | 3kvvA-3obzA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oga | NUCLEOSIDETRIPHOSPHATASE NUDI (Salmonellaenterica) |
PF00293(NUDIX) | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | NoneNoneBME A 142 ( 4.7A)None | 1.01A | 3kvvA-3ogaA:undetectable | 3kvvA-3ogaA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olm | E3 UBIQUITIN-PROTEINLIGASE RSP5 (Saccharomycescerevisiae) |
PF00397(WW)PF00632(HECT) | 4 | GLY A 553MET A 664ILE A 688VAL A 556 | None | 0.93A | 3kvvA-3olmA:undetectable | 3kvvA-3olmA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0f | URIDINEPHOSPHORYLASE 2 (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | GLY A 149GLN A 223ARG A 225MET A 255 | BAU A 400 (-3.5A)BAU A 400 (-3.1A)BAU A 400 (-2.8A)BAU A 400 (-3.9A) | 0.18A | 3kvvA-3p0fA:25.5 | 3kvvA-3p0fA:28.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p94 | GDSL-LIKE LIPASE (Parabacteroidesdistasonis) |
PF13472(Lipase_GDSL_2) | 4 | GLY A 52GLN A 80ARG A 88ILE A 103 | None | 1.03A | 3kvvA-3p94A:3.3 | 3kvvA-3p94A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtd | PMBA PROTEIN (Pseudomonasaeruginosa) |
PF01523(PmbA_TldD) | 4 | GLY A 9GLN A 43ARG A 61VAL A 12 | None | 1.09A | 3kvvA-3qtdA:undetectable | 3kvvA-3qtdA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uqe | 6-PHOSPHOFRUCTOKINASE ISOZYME 2 (Escherichiacoli) |
PF00294(PfkB) | 4 | GLY A 260MET A 275ILE A 48VAL A 44 | None | 1.12A | 3kvvA-3uqeA:undetectable | 3kvvA-3uqeA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbn | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF01554(MatE) | 4 | GLY A 108MET A 115ILE A 150VAL A 151 | NoneNoneOLC A 505 ( 4.4A)None | 0.87A | 3kvvA-3wbnA:undetectable | 3kvvA-3wbnA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvs | PUTATIVEMONOOXYGENASE (Streptomycessp. SN-593) |
PF00067(p450) | 4 | GLY A 159MET A 216ILE A 200VAL A 160 | None | 1.17A | 3kvvA-3wvsA:undetectable | 3kvvA-3wvsA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zth | STU0660 (Streptococcusthermophilus) |
PF16813(Cas_St_Csn2) | 4 | GLY A 25MET A 304ILE A 256VAL A 24 | None | 1.09A | 3kvvA-3zthA:undetectable | 3kvvA-3zthA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyx | AMINE OXIDASE[FLAVIN-CONTAINING]B (Homo sapiens) |
PF01593(Amino_oxidase) | 4 | GLY A 438GLN A 65ILE A 14VAL A 440 | NoneFAD A 600 ( 4.8A)FAD A 600 (-4.8A)None | 1.12A | 3kvvA-3zyxA:undetectable | 3kvvA-3zyxA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1l | 2-DEHYDRO-3-DEOXYPHOSPHOHEPTONATEALDOLASE (Pyrococcusfuriosus) |
PF00793(DAHP_synth_1) | 4 | GLY A 29GLN A 242ILE A 39VAL A 42 | None | 0.97A | 3kvvA-4c1lA:undetectable | 3kvvA-4c1lA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cgt | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | GLY A 225MET A 243ILE A 134VAL A 133 | None | 1.07A | 3kvvA-4cgtA:undetectable | 3kvvA-4cgtA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eew | LARGE PROLINE-RICHPROTEIN BAG6 (Homo sapiens) |
PF00240(ubiquitin) | 4 | GLY A 34GLN A 73ILE A 32VAL A 33 | None | 1.08A | 3kvvA-4eewA:undetectable | 3kvvA-4eewA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gso | THROMBIN-LIKE ENZYMEBJUSSUSP-1 (Bothropsjararacussu) |
PF00089(Trypsin) | 4 | GLY A 190MET A 120ILE A 191VAL A 211 | None | 1.14A | 3kvvA-4gsoA:undetectable | 3kvvA-4gsoA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4haq | GH7 FAMILY PROTEIN (Limnoriaquadripunctata) |
PF00840(Glyco_hydro_7) | 4 | GLY A 189MET A 201ILE A 51VAL A 50 | None | 1.14A | 3kvvA-4haqA:undetectable | 3kvvA-4haqA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jxc | FEFE-HYDROGENASEMATURASE (Thermotogamaritima) |
PF04055(Radical_SAM)PF06968(BATS) | 4 | GLY A 226MET A 271ILE A 265VAL A 225 | None | 1.05A | 3kvvA-4jxcA:undetectable | 3kvvA-4jxcA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5b | COBALAMINBIOSYNTHESIS PROTEINCBIM (Caldanaerobactersubterraneus) |
PF01891(CbiM) | 4 | GLY A 146MET A 187ILE A 116VAL A 120 | NoneHEZ A 302 ( 4.9A)HEZ A 313 (-4.7A)HEZ A 313 ( 4.2A) | 1.17A | 3kvvA-4m5bA:undetectable | 3kvvA-4m5bA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nfy | D-3-PHOSPHOGLYCERATEDEHYDROGENASE,PUTATIVE (Entamoebahistolytica) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | GLY A 210MET A 230ILE A 184VAL A 183 | None | 1.09A | 3kvvA-4nfyA:undetectable | 3kvvA-4nfyA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7y | METHIONINEGAMMA-LYASE (Citrobacterfreundii) |
PF01053(Cys_Met_Meta_PP) | 4 | GLY A 82GLN A 227ILE A 223VAL A 224 | None | 1.12A | 3kvvA-4p7yA:undetectable | 3kvvA-4p7yA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxd | ALLANTOATEAMIDOHYDROLASE (Escherichiacoli) |
PF01546(Peptidase_M20) | 4 | GLY A 212MET A 323ILE A 210VAL A 211 | None1AL A 502 ( 4.7A)NoneNone | 1.11A | 3kvvA-4pxdA:10.0 | 3kvvA-4pxdA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qc6 | BIFUNCTIONAL AAC/APH (Staphylococcuswarneri) |
PF13523(Acetyltransf_8) | 4 | GLY A 97GLN A 100ILE A 134VAL A 133 | None | 1.17A | 3kvvA-4qc6A:undetectable | 3kvvA-4qc6A:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgs | ALCOHOLDEHYDROGENASE YQHD (Escherichiacoli) |
PF00465(Fe-ADH) | 4 | GLY A 270MET A 276ILE A 287VAL A 288 | None | 0.80A | 3kvvA-4qgsA:undetectable | 3kvvA-4qgsA:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r2w | URIDINEPHOSPHORYLASE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 6 | GLY A 93GLN A 163ARG A 165MET A 194ILE A 217VAL A 218 | NoneNoneNoneGOL A 303 (-3.5A)NoneNone | 0.24A | 3kvvA-4r2wA:42.9 | 3kvvA-4r2wA:75.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 6 | GLY A 94GLN A 164ARG A 166MET A 195ILE A 218VAL A 219 | NoneNoneNoneGOL A 301 (-4.0A)NoneNone | 0.83A | 3kvvA-4r31A:42.0 | 3kvvA-4r31A:66.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsh | LIPOLYTIC PROTEING-D-S-L FAMILY (Desulfitobacteriumhafniense) |
PF13472(Lipase_GDSL_2) | 4 | GLY A 60GLN A 95ARG A 103ILE A 118 | None | 1.10A | 3kvvA-4rshA:undetectable | 3kvvA-4rshA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv3 | 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE (Staphylococcusaureus) |
PF00388(PI-PLC-X) | 4 | GLY A 284GLN A 49ILE A 293VAL A 294 | None | 1.09A | 3kvvA-4rv3A:undetectable | 3kvvA-4rv3A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u39 | CELL DIVISION FACTORCELL DIVISIONPROTEIN FTSZ (Bacillussubtilis) |
PF00091(Tubulin)PF12327(FtsZ_C)PF13072(DUF3936) | 4 | GLY A 37MET J 6ILE A 14VAL A 38 | None | 0.98A | 3kvvA-4u39A:2.1 | 3kvvA-4u39A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uav | HALOACIDDEHALOGENASE-LIKEHYDROLASEDOMAIN-CONTAININGPROTEIN AT3G48420 (Arabidopsisthaliana) |
PF13419(HAD_2) | 4 | GLY A 156GLN A 160ARG A 106ILE A 154 | None | 1.14A | 3kvvA-4uavA:2.9 | 3kvvA-4uavA:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpd | RNA-DIRECTED RNAPOLYMERASE (Enterovirus B) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 307ILE A 325 | None | 0.97A | 3kvvA-4zpdA:undetectable | 3kvvA-4zpdA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8z | NEUTROPHIL ELASTASE (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY A 211MET A 139ILE A 212VAL A 231 | None | 1.10A | 3kvvA-5a8zA:undetectable | 3kvvA-5a8zA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a96 | POLYHEDRIN (Cypovirus 14) |
PF17515(CPV_Polyhedrin) | 4 | GLY A 176MET A 173ILE A 115VAL A 177 | None | 1.03A | 3kvvA-5a96A:undetectable | 3kvvA-5a96A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bmt | UNCHARACTERIZEDPROTEIN (Parabacteroidesmerdae) |
no annotation | 4 | GLY A 207MET A 213ILE A 142VAL A 205 | None | 1.16A | 3kvvA-5bmtA:undetectable | 3kvvA-5bmtA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7u | CYCLOALTERNAN-FORMING ENZYME (Listeriamonocytogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF16990(CBM_35) | 4 | GLY A 355GLN A 584ILE A 263VAL A 262 | None | 1.08A | 3kvvA-5f7uA:undetectable | 3kvvA-5f7uA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fim | YGAU (Escherichiacoli) |
PF01476(LysM)PF04972(BON) | 4 | GLY A 11GLN A 142MET A 131ILE A 80 | None | 1.07A | 3kvvA-5fimA:undetectable | 3kvvA-5fimA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gin | 50S RIBOSOMALPROTEIN L7AEC/D BOX METHYLATIONGUIDERIBONUCLEOPROTEINCOMPLEX ANOP56SUBUNIT (Sulfolobussolfataricus) |
PF01248(Ribosomal_L7Ae)PF01798(Nop) | 4 | GLY C 126GLN A 75ARG A 80ILE C 124 | None | 1.09A | 3kvvA-5ginC:undetectable | 3kvvA-5ginC:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l26 | NUCLEOSIDE PERMEASE (Neisseriawadsworthii) |
PF01773(Nucleos_tra2_N)PF07662(Nucleos_tra2_C)PF07670(Gate) | 4 | GLY A 130MET A 135ILE A 128VAL A 127 | NoneNone6ZL A 502 ( 4.7A)6ZL A 502 (-4.4A) | 1.03A | 3kvvA-5l26A:undetectable | 3kvvA-5l26A:20.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhv | URIDINEPHOSPHORYLASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | GLY A 95GLN A 165ARG A 167MET A 196ILE A 219 | URI A 303 ( 3.4A)URA A 304 ( 2.9A)URA A 304 ( 2.9A)URI A 303 ( 3.7A)None | 0.18A | 3kvvA-5lhvA:44.2 | 3kvvA-5lhvA:75.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofu | FBP PROTEIN (Leishmaniamajor) |
PF00316(FBPase) | 4 | GLY A 304ARG A 335ILE A 306VAL A 300 | None | 0.89A | 3kvvA-5ofuA:undetectable | 3kvvA-5ofuA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u47 | PENICILLIN BINDINGPROTEIN 2X (Streptococcusthermophilus) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF03793(PASTA) | 4 | GLY A 304MET A 480ILE A 590VAL A 299 | None | 1.13A | 3kvvA-5u47A:undetectable | 3kvvA-5u47A:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ulj | RAI1 (Scheffersomycesstipitis) |
PF08652(RAI1) | 4 | GLY A 227MET A 111ILE A 214VAL A 213 | 0WD A 402 (-3.5A)NoneNoneNone | 1.17A | 3kvvA-5uljA:undetectable | 3kvvA-5uljA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz5 | 56 KDA U1 SMALLNUCLEARRIBONUCLEOPROTEINCOMPONENT (Saccharomycescerevisiae) |
no annotation | 4 | GLY G 159GLN G 136MET G 74VAL G 203 | None | 1.14A | 3kvvA-5uz5G:undetectable | 3kvvA-5uz5G:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wwt | PUTATIVEMETHYLTRANSFERASENSUN6 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 4 | GLY A 117MET A 335ILE A 115VAL A 116 | A C 76 ( 4.5A)NoneNoneNone | 1.12A | 3kvvA-5wwtA:undetectable | 3kvvA-5wwtA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wzr | ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumbifidum) |
PF11308(Glyco_hydro_129) | 4 | GLY A 509ARG A 501ILE A 140VAL A 138 | None | 1.03A | 3kvvA-5wzrA:undetectable | 3kvvA-5wzrA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b9u | DNA GYRASE, SUBUNITB:SHORT-CHAINDEHYDROGENASE/REDUCTASESDR:GLUCOSE/RIBITOLDEHYDROGENASE (Brucellaabortus) |
no annotation | 4 | GLY A 89ARG A 38ILE A 108VAL A 111 | NAI A 301 (-3.7A)NAI A 301 (-3.4A)NoneNAI A 301 (-4.2A) | 1.11A | 3kvvA-6b9uA:undetectable | 3kvvA-6b9uA:24.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT C (Flavobacteriumjohnsoniae) |
no annotation | 4 | GLY C 312GLN C 358ILE C 310VAL C 311 | None | 1.05A | 3kvvA-6btmC:undetectable | 3kvvA-6btmC:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cdd | NPL4 ZINC FINGER (Chaetomiumthermophilum) |
no annotation | 4 | GLY A 284GLN A 312ILE A 345VAL A 344 | None | 1.08A | 3kvvA-6cddA:undetectable | 3kvvA-6cddA:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT BMONOVALENT CATION/H+ANTIPORTER SUBUNIT F (Pyrococcusfuriosus) |
no annotation | 4 | GLY F 6GLN B 80ILE F 8VAL F 9 | None | 1.00A | 3kvvA-6cfwF:undetectable | 3kvvA-6cfwF:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dt3 | NUCLEOSIDETRIPHOSPHATASE NUDI (Klebsiellapneumoniae) |
no annotation | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | None | 1.00A | 3kvvA-6dt3A:undetectable | 3kvvA-6dt3A:15.87 |