SIMILAR PATTERNS OF AMINO ACIDS FOR 3KVV_A_URFA254_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN


(Propionibacterium
freudenreichii)
PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
4 GLY A 708
GLN A 339
ARG A 471
ILE A 457
B12  A 800 ( 4.4A)
None
None
None
1.14A 3kvvA-1e1cA:
undetectable
3kvvA-1e1cA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0y INTERLEUKIN-1
RECEPTOR, TYPE I


(Homo sapiens)
PF07679
(I-set)
PF13895
(Ig_2)
4 GLY R 121
GLN R 113
ILE R 165
VAL R 166
None
0.99A 3kvvA-1g0yR:
undetectable
3kvvA-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4s ASPARTATE
AMINOTRANSFERASE


(Thermotoga
maritima)
PF00155
(Aminotran_1_2)
4 GLY A 244
MET A 238
ILE A 267
VAL A  94
None
0.88A 3kvvA-1o4sA:
undetectable
3kvvA-1o4sA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oed ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN


(Torpedo
marmorata)
PF02932
(Neur_chan_memb)
4 GLY C 301
MET C 293
ILE C 303
VAL C 304
None
0.92A 3kvvA-1oedC:
undetectable
3kvvA-1oedC:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3x MANNAN-BINDING
LECTIN SERINE
PROTEASE 2


(Homo sapiens)
PF00084
(Sushi)
PF00089
(Trypsin)
4 GLY A 634
GLN A 459
ILE A 652
VAL A 653
None
None
None
GOL  A 701 (-4.9A)
1.14A 3kvvA-1q3xA:
undetectable
3kvvA-1q3xA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I


(Escherichia
coli)
PF00015
(MCPsignal)
4 GLY A 370
GLN A 374
ILE A 368
VAL A 367
None
1.09A 3kvvA-1qu7A:
undetectable
3kvvA-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6m RIBONUCLEASE PH

(Pseudomonas
aeruginosa)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
4 GLY A 133
GLN A 233
MET A 159
VAL A  29
None
1.08A 3kvvA-1r6mA:
undetectable
3kvvA-1r6mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1raj GENOME POLYPROTEIN

(Enterovirus C)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 306
ILE A 324
None
1.17A 3kvvA-1rajA:
undetectable
3kvvA-1rajA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rdr POLIOVIRUS 3D
POLYMERASE


(Enterovirus C)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 306
ILE A 324
None
1.06A 3kvvA-1rdrA:
undetectable
3kvvA-1rdrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE ALPHA
SUBUNIT
4-HYDROXYBENZOYL-COA
REDUCTASE GAMMA
SUBUNIT


(Thauera
aromatica)
PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
4 GLY C 139
GLN C  99
ILE A 705
VAL C 141
None
PCD  A1920 ( 4.0A)
None
None
1.14A 3kvvA-1sb3C:
undetectable
3kvvA-1sb3C:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0i YLR011WP

(Saccharomyces
cerevisiae)
PF03358
(FMN_red)
4 GLY A 126
GLN A  94
ILE A 155
VAL A 157
FMN  A 200 (-3.7A)
FMN  A 200 (-3.9A)
None
FMN  A 200 (-4.4A)
1.08A 3kvvA-1t0iA:
3.0
3kvvA-1t0iA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp7 GENOME POLYPROTEIN

(Rhinovirus A)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
1.11A 3kvvA-1tp7A:
undetectable
3kvvA-1tp7A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL


(Escherichia
coli)
PF00155
(Aminotran_1_2)
4 GLY A 346
GLN A 385
ILE A  33
VAL A 347
None
1.08A 3kvvA-1u08A:
undetectable
3kvvA-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uou THYMIDINE
PHOSPHORYLASE


(Homo sapiens)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 GLY A 186
ARG A 146
ILE A 167
VAL A 166
None
1.11A 3kvvA-1uouA:
3.9
3kvvA-1uouA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us4 PUTATIVE GLUR0
LIGAND BINDING CORE


(Thermus
thermophilus)
PF16868
(NMT1_3)
4 GLY A 172
GLN A 174
ILE A 165
VAL A 167
None
1.04A 3kvvA-1us4A:
undetectable
3kvvA-1us4A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vr9 CBS DOMAIN
PROTEIN/ACT DOMAIN
PROTEIN


(Thermotoga
maritima)
PF00571
(CBS)
4 GLY A  46
MET A 101
ILE A  36
VAL A  47
None
1.07A 3kvvA-1vr9A:
undetectable
3kvvA-1vr9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wol 122AA LONG CONSERVED
HYPOTHETICAL PROTEIN


(Sulfurisphaera
tokodaii)
PF05168
(HEPN)
4 GLY A  44
GLN A  49
ILE A   8
VAL A   4
None
1.04A 3kvvA-1wolA:
undetectable
3kvvA-1wolA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wr8 PHOSPHOGLYCOLATE
PHOSPHATASE


(Pyrococcus
horikoshii)
PF08282
(Hydrolase_3)
4 GLY A 176
GLN A 196
ILE A   8
VAL A 175
None
1.07A 3kvvA-1wr8A:
3.5
3kvvA-1wr8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr6 GENOME POLYPROTEIN

(Rhinovirus A)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.98A 3kvvA-1xr6A:
undetectable
3kvvA-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aip PROTEIN C ACTIVATOR

(Agkistrodon
contortrix)
PF00089
(Trypsin)
4 GLY A 211
MET A 139
ILE A 212
VAL A 231
None
1.15A 3kvvA-2aipA:
undetectable
3kvvA-2aipA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
4 GLY A 126
GLN A 123
ILE A 128
VAL A 127
None
1.05A 3kvvA-2eyyA:
undetectable
3kvvA-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gxa REPLICATION PROTEIN
E1


(Deltapapillomavirus
4)
PF00519
(PPV_E1_C)
4 GLN A 374
ARG A 370
ILE A 503
VAL A 511
None
1.05A 3kvvA-2gxaA:
undetectable
3kvvA-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE


(Enterovirus C)
PF00548
(Peptidase_C3)
PF00680
(RdRP_1)
4 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
None
1.01A 3kvvA-2ijd1:
undetectable
3kvvA-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5t GLUTAMATE 5-KINASE

(Escherichia
coli)
PF00696
(AA_kinase)
PF01472
(PUA)
4 GLY A 243
GLN A  34
ILE A 249
VAL A 245
None
1.15A 3kvvA-2j5tA:
undetectable
3kvvA-2j5tA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfd FATTY ACID SYNTHASE

(Homo sapiens)
PF00698
(Acyl_transf_1)
PF16197
(KAsynt_C_assoc)
4 GLY A 579
MET A 499
ILE A 495
VAL A 578
None
1.13A 3kvvA-2jfdA:
undetectable
3kvvA-2jfdA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mx6 SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1


(Mus musculus)
PF00595
(PDZ)
4 GLY A 281
MET A 284
ILE A 266
VAL A 267
None
0.96A 3kvvA-2mx6A:
undetectable
3kvvA-2mx6A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nbg TRANSLATION
INITIATION FACTOR
IF-2


(Geobacillus
stearothermophilus)
no annotation 4 GLY A 447
MET A 400
ILE A 450
VAL A 459
None
1.17A 3kvvA-2nbgA:
undetectable
3kvvA-2nbgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oce HYPOTHETICAL PROTEIN
PA5201


(Pseudomonas
aeruginosa)
PF00575
(S1)
PF09371
(Tex_N)
PF12836
(HHH_3)
PF16921
(Tex_YqgF)
4 GLY A 660
GLN A 643
ILE A 704
VAL A 661
None
0.97A 3kvvA-2oceA:
undetectable
3kvvA-2oceA:
16.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oxf URIDINE
PHOSPHORYLASE


(Salmonella
enterica)
PF01048
(PNP_UDP_1)
4 GLY A1096
GLN A1166
ARG A1168
MET A1197
None
0.70A 3kvvA-2oxfA:
43.8
3kvvA-2oxfA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oxf URIDINE
PHOSPHORYLASE


(Salmonella
enterica)
PF01048
(PNP_UDP_1)
4 GLY A1096
GLN A1166
MET A1197
VAL A1221
None
0.78A 3kvvA-2oxfA:
43.8
3kvvA-2oxfA:
97.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbi REGULATOR OF
G-PROTEIN SIGNALING
9


(Mus musculus)
PF00610
(DEP)
PF00615
(RGS)
PF00631
(G-gamma)
4 GLY A  74
GLN A  71
ILE A  83
VAL A  78
None
1.10A 3kvvA-2pbiA:
undetectable
3kvvA-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqp LARGE CAPSID PROTEIN

(Providence
virus)
PF03566
(Peptidase_A21)
4 GLY A 549
MET A 445
ILE A 440
VAL A 550
None
1.03A 3kvvA-2qqpA:
undetectable
3kvvA-2qqpA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqp SMALL CAPSID PROTEIN

(Providence
virus)
PF03566
(Peptidase_A21)
4 GLY B 584
GLN B 588
ILE B 582
VAL B 581
None
1.14A 3kvvA-2qqpB:
undetectable
3kvvA-2qqpB:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qy0 COMPLEMENT C1R
SUBCOMPONENT


(Homo sapiens)
PF00089
(Trypsin)
4 GLY B 638
GLN B 461
ILE B 656
VAL B 657
None
1.14A 3kvvA-2qy0B:
undetectable
3kvvA-2qy0B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9p REPLICATION PROTEIN
E1


(Deltapapillomavirus
4)
PF00519
(PPV_E1_C)
4 GLN A 374
ARG A 370
ILE A 503
VAL A 511
None
0.91A 3kvvA-2v9pA:
undetectable
3kvvA-2v9pA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhe UNC18

(Monosiga
brevicollis)
PF00995
(Sec1)
4 GLN A 199
ARG A 500
ILE A 211
VAL A 206
None
1.01A 3kvvA-2xheA:
undetectable
3kvvA-2xheA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis)
PF01593
(Amino_oxidase)
4 GLY A 435
GLN A  65
ILE A  15
VAL A 437
None
FAD  A 600 ( 4.5A)
None
None
1.13A 3kvvA-2yg6A:
undetectable
3kvvA-2yg6A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A


(Homo sapiens)
PF01593
(Amino_oxidase)
4 GLY A 447
GLN A  74
ILE A  23
VAL A 449
None
FAD  A 600 ( 4.7A)
FAD  A 600 (-4.9A)
None
1.09A 3kvvA-2z5xA:
undetectable
3kvvA-2z5xA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1i AMIDASE

(Rhodococcus sp.
N-771)
PF01425
(Amidase)
4 GLY A 137
MET A 106
ILE A  80
VAL A 135
None
1.04A 3kvvA-3a1iA:
undetectable
3kvvA-3a1iA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ada SARCOSINE OXIDASE
BETA SUBUNIT


(Corynebacterium
sp. U-96)
PF01266
(DAO)
4 GLY B  28
MET B  61
ILE B 190
VAL B  50
FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
1.11A 3kvvA-3adaB:
undetectable
3kvvA-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bje NUCLEOSIDE
PHOSPHORYLASE,
PUTATIVE


(Trypanosoma
brucei)
PF01048
(PNP_UDP_1)
4 GLY A 142
GLN A 246
ARG A 248
MET A 285
URA  A 501 (-3.4A)
URA  A 501 (-3.0A)
URA  A 501 (-2.9A)
R1P  A 401 ( 3.9A)
0.20A 3kvvA-3bjeA:
30.5
3kvvA-3bjeA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctz XAA-PRO
AMINOPEPTIDASE 1


(Homo sapiens)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2)
4 GLY A 492
GLN A 419
ILE A 519
VAL A 491
None
1.09A 3kvvA-3ctzA:
undetectable
3kvvA-3ctzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epj TRNA
ISOPENTENYLTRANSFERA
SE


(Saccharomyces
cerevisiae)
PF01715
(IPPT)
4 GLY A 110
GLN A  49
MET A  74
ILE A  19
None
1.11A 3kvvA-3epjA:
2.8
3kvvA-3epjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euf URIDINE
PHOSPHORYLASE 1


(Homo sapiens)
PF01048
(PNP_UDP_1)
4 GLY A 143
GLN A 217
ARG A 219
MET A 249
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
0.23A 3kvvA-3eufA:
25.8
3kvvA-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flb RIFR

(Amycolatopsis
mediterranei)
PF00975
(Thioesterase)
4 GLY A  56
GLN A  53
ILE A 170
VAL A 166
None
1.07A 3kvvA-3flbA:
undetectable
3kvvA-3flbA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdo UNCHARACTERIZED
OXIDOREDUCTASE YVAA


(Bacillus
subtilis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 GLY A 237
MET A 209
ILE A 239
VAL A 240
None
0.93A 3kvvA-3gdoA:
undetectable
3kvvA-3gdoA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gpi NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E


(Methylobacillus
flagellatus)
PF13460
(NAD_binding_10)
4 GLY A   8
GLN A  35
ARG A  32
VAL A  69
None
1.07A 3kvvA-3gpiA:
2.7
3kvvA-3gpiA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6


(Homo sapiens)
PF00293
(NUDIX)
4 GLY A 145
GLN A 143
ILE A 225
VAL A 146
None
0.96A 3kvvA-3h95A:
undetectable
3kvvA-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1


(Manduca sexta)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
4 GLY B 244
GLN B 257
MET B 251
ILE B 526
None
1.12A 3kvvA-3hhsB:
undetectable
3kvvA-3hhsB:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvy URIDINE
PHOSPHORYLASE


(Bos taurus)
PF01048
(PNP_UDP_1)
4 GLY A 142
GLN A 216
ARG A 218
MET A 248
URA  A 312 (-3.3A)
URA  A 312 (-3.3A)
URA  A 312 (-2.9A)
URA  A 312 ( 3.7A)
0.25A 3kvvA-3kvyA:
26.0
3kvvA-3kvyA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5m ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE


(Bacillus
anthracis)
PF00202
(Aminotran_3)
4 GLY A 224
GLN A 159
ARG A 162
ILE A 255
None
1.17A 3kvvA-3n5mA:
undetectable
3kvvA-3n5mA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF05721
(PhyH)
4 GLY A  37
GLN A 258
ILE A  39
VAL A  40
None
1.01A 3kvvA-3obzA:
undetectable
3kvvA-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oga NUCLEOSIDE
TRIPHOSPHATASE NUDI


(Salmonella
enterica)
PF00293
(NUDIX)
4 GLY A  37
ARG A  52
ILE A   6
VAL A   7
None
None
BME  A 142 ( 4.7A)
None
1.01A 3kvvA-3ogaA:
undetectable
3kvvA-3ogaA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5


(Saccharomyces
cerevisiae)
PF00397
(WW)
PF00632
(HECT)
4 GLY A 553
MET A 664
ILE A 688
VAL A 556
None
0.93A 3kvvA-3olmA:
undetectable
3kvvA-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0f URIDINE
PHOSPHORYLASE 2


(Homo sapiens)
PF01048
(PNP_UDP_1)
4 GLY A 149
GLN A 223
ARG A 225
MET A 255
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
0.18A 3kvvA-3p0fA:
25.5
3kvvA-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p94 GDSL-LIKE LIPASE

(Parabacteroides
distasonis)
PF13472
(Lipase_GDSL_2)
4 GLY A  52
GLN A  80
ARG A  88
ILE A 103
None
1.03A 3kvvA-3p94A:
3.3
3kvvA-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtd PMBA PROTEIN

(Pseudomonas
aeruginosa)
PF01523
(PmbA_TldD)
4 GLY A   9
GLN A  43
ARG A  61
VAL A  12
None
1.09A 3kvvA-3qtdA:
undetectable
3kvvA-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uqe 6-PHOSPHOFRUCTOKINAS
E ISOZYME 2


(Escherichia
coli)
PF00294
(PfkB)
4 GLY A 260
MET A 275
ILE A  48
VAL A  44
None
1.12A 3kvvA-3uqeA:
undetectable
3kvvA-3uqeA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbn PUTATIVE
UNCHARACTERIZED
PROTEIN


(Pyrococcus
furiosus)
PF01554
(MatE)
4 GLY A 108
MET A 115
ILE A 150
VAL A 151
None
None
OLC  A 505 ( 4.4A)
None
0.87A 3kvvA-3wbnA:
undetectable
3kvvA-3wbnA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvs PUTATIVE
MONOOXYGENASE


(Streptomyces
sp. SN-593)
PF00067
(p450)
4 GLY A 159
MET A 216
ILE A 200
VAL A 160
None
1.17A 3kvvA-3wvsA:
undetectable
3kvvA-3wvsA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zth STU0660

(Streptococcus
thermophilus)
PF16813
(Cas_St_Csn2)
4 GLY A  25
MET A 304
ILE A 256
VAL A  24
None
1.09A 3kvvA-3zthA:
undetectable
3kvvA-3zthA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyx AMINE OXIDASE
[FLAVIN-CONTAINING]
B


(Homo sapiens)
PF01593
(Amino_oxidase)
4 GLY A 438
GLN A  65
ILE A  14
VAL A 440
None
FAD  A 600 ( 4.8A)
FAD  A 600 (-4.8A)
None
1.12A 3kvvA-3zyxA:
undetectable
3kvvA-3zyxA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1l 2-DEHYDRO-3-DEOXYPHO
SPHOHEPTONATE
ALDOLASE


(Pyrococcus
furiosus)
PF00793
(DAHP_synth_1)
4 GLY A  29
GLN A 242
ILE A  39
VAL A  42
None
0.97A 3kvvA-4c1lA:
undetectable
3kvvA-4c1lA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgt CYCLODEXTRIN
GLYCOSYLTRANSFERASE


(Bacillus
circulans)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C)
4 GLY A 225
MET A 243
ILE A 134
VAL A 133
None
1.07A 3kvvA-4cgtA:
undetectable
3kvvA-4cgtA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eew LARGE PROLINE-RICH
PROTEIN BAG6


(Homo sapiens)
PF00240
(ubiquitin)
4 GLY A  34
GLN A  73
ILE A  32
VAL A  33
None
1.08A 3kvvA-4eewA:
undetectable
3kvvA-4eewA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gso THROMBIN-LIKE ENZYME
BJUSSUSP-1


(Bothrops
jararacussu)
PF00089
(Trypsin)
4 GLY A 190
MET A 120
ILE A 191
VAL A 211
None
1.14A 3kvvA-4gsoA:
undetectable
3kvvA-4gsoA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4haq GH7 FAMILY PROTEIN

(Limnoria
quadripunctata)
PF00840
(Glyco_hydro_7)
4 GLY A 189
MET A 201
ILE A  51
VAL A  50
None
1.14A 3kvvA-4haqA:
undetectable
3kvvA-4haqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxc FEFE-HYDROGENASE
MATURASE


(Thermotoga
maritima)
PF04055
(Radical_SAM)
PF06968
(BATS)
4 GLY A 226
MET A 271
ILE A 265
VAL A 225
None
1.05A 3kvvA-4jxcA:
undetectable
3kvvA-4jxcA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5b COBALAMIN
BIOSYNTHESIS PROTEIN
CBIM


(Caldanaerobacter
subterraneus)
PF01891
(CbiM)
4 GLY A 146
MET A 187
ILE A 116
VAL A 120
None
HEZ  A 302 ( 4.9A)
HEZ  A 313 (-4.7A)
HEZ  A 313 ( 4.2A)
1.17A 3kvvA-4m5bA:
undetectable
3kvvA-4m5bA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfy D-3-PHOSPHOGLYCERATE
DEHYDROGENASE,
PUTATIVE


(Entamoeba
histolytica)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 GLY A 210
MET A 230
ILE A 184
VAL A 183
None
1.09A 3kvvA-4nfyA:
undetectable
3kvvA-4nfyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7y METHIONINE
GAMMA-LYASE


(Citrobacter
freundii)
PF01053
(Cys_Met_Meta_PP)
4 GLY A  82
GLN A 227
ILE A 223
VAL A 224
None
1.12A 3kvvA-4p7yA:
undetectable
3kvvA-4p7yA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxd ALLANTOATE
AMIDOHYDROLASE


(Escherichia
coli)
PF01546
(Peptidase_M20)
4 GLY A 212
MET A 323
ILE A 210
VAL A 211
None
1AL  A 502 ( 4.7A)
None
None
1.11A 3kvvA-4pxdA:
10.0
3kvvA-4pxdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qc6 BIFUNCTIONAL AAC/APH

(Staphylococcus
warneri)
PF13523
(Acetyltransf_8)
4 GLY A  97
GLN A 100
ILE A 134
VAL A 133
None
1.17A 3kvvA-4qc6A:
undetectable
3kvvA-4qc6A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgs ALCOHOL
DEHYDROGENASE YQHD


(Escherichia
coli)
PF00465
(Fe-ADH)
4 GLY A 270
MET A 276
ILE A 287
VAL A 288
None
0.80A 3kvvA-4qgsA:
undetectable
3kvvA-4qgsA:
22.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r2w URIDINE
PHOSPHORYLASE


(Shewanella
oneidensis)
PF01048
(PNP_UDP_1)
6 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
None
None
None
GOL  A 303 (-3.5A)
None
None
0.24A 3kvvA-4r2wA:
42.9
3kvvA-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r31 URIDINE
PHOSPHORYLASE


(Actinobacillus
succinogenes)
PF01048
(PNP_UDP_1)
6 GLY A  94
GLN A 164
ARG A 166
MET A 195
ILE A 218
VAL A 219
None
None
None
GOL  A 301 (-4.0A)
None
None
0.83A 3kvvA-4r31A:
42.0
3kvvA-4r31A:
66.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rsh LIPOLYTIC PROTEIN
G-D-S-L FAMILY


(Desulfitobacterium
hafniense)
PF13472
(Lipase_GDSL_2)
4 GLY A  60
GLN A  95
ARG A 103
ILE A 118
None
1.10A 3kvvA-4rshA:
undetectable
3kvvA-4rshA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE


(Staphylococcus
aureus)
PF00388
(PI-PLC-X)
4 GLY A 284
GLN A  49
ILE A 293
VAL A 294
None
1.09A 3kvvA-4rv3A:
undetectable
3kvvA-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ


(Bacillus
subtilis)
PF00091
(Tubulin)
PF12327
(FtsZ_C)
PF13072
(DUF3936)
4 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 3kvvA-4u39A:
2.1
3kvvA-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uav HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN AT3G48420


(Arabidopsis
thaliana)
PF13419
(HAD_2)
4 GLY A 156
GLN A 160
ARG A 106
ILE A 154
None
1.14A 3kvvA-4uavA:
2.9
3kvvA-4uavA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpd RNA-DIRECTED RNA
POLYMERASE


(Enterovirus B)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 307
ILE A 325
None
0.97A 3kvvA-4zpdA:
undetectable
3kvvA-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8z NEUTROPHIL ELASTASE

(Homo sapiens)
PF00089
(Trypsin)
4 GLY A 211
MET A 139
ILE A 212
VAL A 231
None
1.10A 3kvvA-5a8zA:
undetectable
3kvvA-5a8zA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a96 POLYHEDRIN

(Cypovirus 14)
PF17515
(CPV_Polyhedrin)
4 GLY A 176
MET A 173
ILE A 115
VAL A 177
None
1.03A 3kvvA-5a96A:
undetectable
3kvvA-5a96A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmt UNCHARACTERIZED
PROTEIN


(Parabacteroides
merdae)
no annotation 4 GLY A 207
MET A 213
ILE A 142
VAL A 205
None
1.16A 3kvvA-5bmtA:
undetectable
3kvvA-5bmtA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7u CYCLOALTERNAN-FORMIN
G ENZYME


(Listeria
monocytogenes)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF16990
(CBM_35)
4 GLY A 355
GLN A 584
ILE A 263
VAL A 262
None
1.08A 3kvvA-5f7uA:
undetectable
3kvvA-5f7uA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fim YGAU

(Escherichia
coli)
PF01476
(LysM)
PF04972
(BON)
4 GLY A  11
GLN A 142
MET A 131
ILE A  80
None
1.07A 3kvvA-5fimA:
undetectable
3kvvA-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gin 50S RIBOSOMAL
PROTEIN L7AE
C/D BOX METHYLATION
GUIDE
RIBONUCLEOPROTEIN
COMPLEX ANOP56
SUBUNIT


(Sulfolobus
solfataricus)
PF01248
(Ribosomal_L7Ae)
PF01798
(Nop)
4 GLY C 126
GLN A  75
ARG A  80
ILE C 124
None
1.09A 3kvvA-5ginC:
undetectable
3kvvA-5ginC:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l26 NUCLEOSIDE PERMEASE

(Neisseria
wadsworthii)
PF01773
(Nucleos_tra2_N)
PF07662
(Nucleos_tra2_C)
PF07670
(Gate)
4 GLY A 130
MET A 135
ILE A 128
VAL A 127
None
None
6ZL  A 502 ( 4.7A)
6ZL  A 502 (-4.4A)
1.03A 3kvvA-5l26A:
undetectable
3kvvA-5l26A:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lhv URIDINE
PHOSPHORYLASE


(Vibrio cholerae)
PF01048
(PNP_UDP_1)
5 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
0.18A 3kvvA-5lhvA:
44.2
3kvvA-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofu FBP PROTEIN

(Leishmania
major)
PF00316
(FBPase)
4 GLY A 304
ARG A 335
ILE A 306
VAL A 300
None
0.89A 3kvvA-5ofuA:
undetectable
3kvvA-5ofuA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u47 PENICILLIN BINDING
PROTEIN 2X


(Streptococcus
thermophilus)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF03793
(PASTA)
4 GLY A 304
MET A 480
ILE A 590
VAL A 299
None
1.13A 3kvvA-5u47A:
undetectable
3kvvA-5u47A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ulj RAI1

(Scheffersomyces
stipitis)
PF08652
(RAI1)
4 GLY A 227
MET A 111
ILE A 214
VAL A 213
0WD  A 402 (-3.5A)
None
None
None
1.17A 3kvvA-5uljA:
undetectable
3kvvA-5uljA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 56 KDA U1 SMALL
NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT


(Saccharomyces
cerevisiae)
no annotation 4 GLY G 159
GLN G 136
MET G  74
VAL G 203
None
1.14A 3kvvA-5uz5G:
undetectable
3kvvA-5uz5G:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwt PUTATIVE
METHYLTRANSFERASE
NSUN6


(Homo sapiens)
PF01189
(Methyltr_RsmB-F)
4 GLY A 117
MET A 335
ILE A 115
VAL A 116
A  C  76 ( 4.5A)
None
None
None
1.12A 3kvvA-5wwtA:
undetectable
3kvvA-5wwtA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE


(Bifidobacterium
bifidum)
PF11308
(Glyco_hydro_129)
4 GLY A 509
ARG A 501
ILE A 140
VAL A 138
None
1.03A 3kvvA-5wzrA:
undetectable
3kvvA-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9u DNA GYRASE, SUBUNIT
B:SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
SDR:GLUCOSE/RIBITOL
DEHYDROGENASE


(Brucella
abortus)
no annotation 4 GLY A  89
ARG A  38
ILE A 108
VAL A 111
NAI  A 301 (-3.7A)
NAI  A 301 (-3.4A)
None
NAI  A 301 (-4.2A)
1.11A 3kvvA-6b9uA:
undetectable
3kvvA-6b9uA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT C


(Flavobacterium
johnsoniae)
no annotation 4 GLY C 312
GLN C 358
ILE C 310
VAL C 311
None
1.05A 3kvvA-6btmC:
undetectable
3kvvA-6btmC:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cdd NPL4 ZINC FINGER

(Chaetomium
thermophilum)
no annotation 4 GLY A 284
GLN A 312
ILE A 345
VAL A 344
None
1.08A 3kvvA-6cddA:
undetectable
3kvvA-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT B
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT F


(Pyrococcus
furiosus)
no annotation 4 GLY F   6
GLN B  80
ILE F   8
VAL F   9
None
1.00A 3kvvA-6cfwF:
undetectable
3kvvA-6cfwF:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dt3 NUCLEOSIDE
TRIPHOSPHATASE NUDI


(Klebsiella
pneumoniae)
no annotation 4 GLY A  37
ARG A  52
ILE A   6
VAL A   7
None
1.00A 3kvvA-6dt3A:
undetectable
3kvvA-6dt3A:
15.87