SIMILAR PATTERNS OF AMINO ACIDS FOR 3KU1_G_SAMG226_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b41 | ACETYLCHOLINESTERASE (Homo sapiens) |
PF00135(COesterase) | 5 | LEU A 324GLY A 210PRO A 312GLY A 205ILE A 118 | None | 1.08A | 3ku1G-1b41A:undetectable | 3ku1G-1b41A:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1chm | CREATINEAMIDINOHYDROLASE (Pseudomonasputida) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | LEU A 31ALA A 43GLY A 122LEU A 136ILE A 111 | None | 1.15A | 3ku1G-1chmA:undetectable | 3ku1G-1chmA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2p | AMINOPEPTIDASE (Streptomycesgriseus) |
PF04389(Peptidase_M28) | 5 | GLY A 64GLY A 137ALA A 62GLY A 61ILE A 136 | None | 1.13A | 3ku1G-1f2pA:undetectable | 3ku1G-1f2pA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq2 | MALIC ENZYME (Columba livia) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 163ASP A 256GLY A 206GLY A 170LEU A 212 | None MN A1584 ( 2.5A)NoneNoneNone | 1.19A | 3ku1G-1gq2A:undetectable | 3ku1G-1gq2A:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2h | HYPOTHETICAL PROTEINTM1643 (Thermotogamaritima) |
PF01958(DUF108)PF03447(NAD_binding_3) | 5 | LEU A 222GLY A 170GLY A 111LEU A 116ILE A 172 | None | 1.12A | 3ku1G-1h2hA:5.2 | 3ku1G-1h2hA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg0 | L-ASPARAGINASE (Dickeyachrysanthemi) |
PF00710(Asparaginase) | 5 | LEU A 174ASN A 59GLY A 32GLY A 131LEU A 39 | None | 1.11A | 3ku1G-1hg0A:undetectable | 3ku1G-1hg0A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kl7 | THREONINE SYNTHASE (Saccharomycescerevisiae) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | ASP A 389ASN A 338GLY A 280ALA A 288ILE A 247 | NoneNonePLP A1400 (-3.8A)NoneNone | 1.08A | 3ku1G-1kl7A:undetectable | 3ku1G-1kl7A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n4o | L2 BETA-LACTAMASE (Stenotrophomonasmaltophilia) |
PF13354(Beta-lactamase2) | 5 | ASP A 242ALA A 41GLY A 42LEU A 36ILE A 27 | None | 0.92A | 3ku1G-1n4oA:undetectable | 3ku1G-1n4oA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ois | DNA TOPOISOMERASE I (Saccharomycescerevisiae) |
PF02919(Topoisom_I_N) | 5 | LEU A 177GLY A 303ALA A 185GLY A 186LEU A 191 | None | 1.18A | 3ku1G-1oisA:undetectable | 3ku1G-1oisA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ouv | CONSERVEDHYPOTHETICALSECRETED PROTEIN (Helicobacterpylori) |
PF08238(Sel1) | 5 | GLY A 135GLY A 140GLY A 104LEU A 121ILE A 142 | None | 1.19A | 3ku1G-1ouvA:undetectable | 3ku1G-1ouvA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3h | DEPHOSPHO-COA KINASE (Escherichiacoli) |
PF01121(CoaE) | 5 | GLY A 9VAL A 132GLY A 12LEU A 156ILE A 11 | NoneNoneSO4 A 301 (-3.2A)NoneNone | 1.17A | 3ku1G-1t3hA:undetectable | 3ku1G-1t3hA:25.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u0u | DIHYDROPINOSYLVINSYNTHASE (Pinussylvestris) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | LEU A 266GLY A 166GLY A 375GLY A 258LEU A 380 | None | 1.10A | 3ku1G-1u0uA:undetectable | 3ku1G-1u0uA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uz5 | 402AA LONGHYPOTHETICALMOLYBDOPTERINBIOSYNTHESIS MOEAPROTEIN (Pyrococcushorikoshii) |
PF00994(MoCF_biosynth)PF03453(MoeA_N)PF03454(MoeA_C) | 5 | GLY A 278ASN A 310GLY A 284LEU A 9ILE A 281 | NoneNoneSO4 A1406 (-4.1A)NoneNone | 1.09A | 3ku1G-1uz5A:undetectable | 3ku1G-1uz5A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve1 | O-ACETYLSERINESULFHYDRYLASE (Thermusthermophilus) |
PF00291(PALP) | 5 | LEU A 234GLY A 173PRO A 201GLY A 177ILE A 39 | NoneNoneNonePLP A 413 (-3.8A)None | 0.89A | 3ku1G-1ve1A:2.6 | 3ku1G-1ve1A:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w52 | PANCREATIC LIPASERELATED PROTEIN 2 (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 5 | GLY X 127ALA X 160GLY X 161LEU X 167ILE X 134 | None | 1.01A | 3ku1G-1w52X:undetectable | 3ku1G-1w52X:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqt | SUPEROXIDE DISMUTASE[CU-ZN] (Neisseriameningitidis) |
no annotation | 5 | GLY C 124GLY C 103ALA C 121GLY C 114LEU C 173 | None | 1.09A | 3ku1G-2aqtC:undetectable | 3ku1G-2aqtC:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2asb | TRANSCRIPTIONELONGATION PROTEINNUSA (Mycobacteriumtuberculosis) |
PF13184(KH_5) | 5 | ARG A 162GLY A 136ALA A 116GLY A 117ILE A 179 | None | 1.18A | 3ku1G-2asbA:undetectable | 3ku1G-2asbA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvm | 439AA LONGHYPOTHETICAL MALATEOXIDOREDUCTASE (Pyrococcushorikoshii) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 209ALA A 171GLY A 172LEU A 177ILE A 184 | None | 0.97A | 3ku1G-2dvmA:undetectable | 3ku1G-2dvmA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6k | TRANSKETOLASE (Thermusthermophilus) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ARG A 208GLY A 129ALA A 171GLY A 168ILE A 412 | None | 0.86A | 3ku1G-2e6kA:undetectable | 3ku1G-2e6kA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 5 | ARG A 316GLY A 251GLY A 256ALA A 166ILE A 137 | None | 1.10A | 3ku1G-2exaA:undetectable | 3ku1G-2exaA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ip4 | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Thermusthermophilus) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | GLY A 369GLY A 339ALA A 328LEU A 342ILE A 340 | SO4 A 419 ( 4.8A)NoneNoneNoneNone | 1.04A | 3ku1G-2ip4A:4.2 | 3ku1G-2ip4A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3s | FILAMIN-A (Homo sapiens) |
PF00630(Filamin) | 5 | LEU A2162PRO A2181GLY A2237ALA A2266GLY A2267 | None | 0.83A | 3ku1G-2j3sA:undetectable | 3ku1G-2j3sA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lfu | GNA2132 (Neisseriameningitidis) |
PF01298(TbpB_B_D) | 5 | VAL A 401GLY A 376ALA A 314GLY A 315ILE A 372 | None | 0.77A | 3ku1G-2lfuA:undetectable | 3ku1G-2lfuA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p1r | LIPID KINASE YEGS (Salmonellaenterica) |
PF00781(DAGK_cat) | 5 | LEU A 169GLY A 68ASP A 269VAL A 73ALA A 96 | None | 0.84A | 3ku1G-2p1rA:undetectable | 3ku1G-2p1rA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q6t | DNAB REPLICATIONFORK HELICASE (Thermusaquaticus) |
PF00772(DnaB)PF03796(DnaB_C) | 5 | GLY A 233ASP A 288GLY A 312LEU A 352ILE A 354 | None | 1.02A | 3ku1G-2q6tA:undetectable | 3ku1G-2q6tA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8w | AGR_C_1641P (Agrobacteriumfabrum) |
PF00701(DHDPS) | 5 | GLY A 221ALA A 204GLY A 205LEU A 210ILE A 220 | None | 0.85A | 3ku1G-2r8wA:undetectable | 3ku1G-2r8wA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqh | UDP-N-ACETYLGLUCOSAMINEPYROPHOSPHORYLASE (Candidaalbicans) |
PF01704(UDPGP) | 5 | LEU A 117GLY A 112ASN A 198GLY A 171GLY A 124 | None | 1.01A | 3ku1G-2yqhA:undetectable | 3ku1G-2yqhA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ze4 | PHOSPHOLIPASE D (Streptomycesantibioticus) |
PF13091(PLDc_2) | 5 | GLY A 359ASP A 355ASN A 419GLY A 364ALA A 326 | None | 1.19A | 3ku1G-2ze4A:1.9 | 3ku1G-2ze4A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3baz | HYDROXYPHENYLPYRUVATE REDUCTASE (Plectranthusscutellarioides) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 241VAL A 147ALA A 253GLY A 252LEU A 116 | None | 0.89A | 3ku1G-3bazA:6.4 | 3ku1G-3bazA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bj1 | HEMOGLOBIN ALPHAHEMOGLOBIN BETA (Percaflavescens;Percaflavescens) |
PF00042(Globin)PF00042(Globin) | 5 | GLY A 30VAL A 35GLY B 124ALA A 26GLY A 25 | None | 0.91A | 3ku1G-3bj1A:undetectable | 3ku1G-3bj1A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c41 | AMINO ACID ABCTRANSPORTER (ARTP) (Geobacillusstearothermophilus) |
PF00005(ABC_tran) | 5 | LEU J 151VAL J 30GLY J 80LEU J 47ILE J 2 | None | 1.11A | 3ku1G-3c41J:undetectable | 3ku1G-3c41J:25.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cir | FUMARATE REDUCTASEIRON-SULFUR SUBUNIT (Escherichiacoli) |
PF13085(Fer2_3)PF13183(Fer4_8) | 5 | GLY B 152PRO B 73GLY B 63ALA B 171ILE B 149 | SF4 B 246 (-4.2A)NoneFES B 244 (-3.7A)SF4 B 246 ( 3.8A)SF4 B 246 (-4.9A) | 1.12A | 3ku1G-3cirB:undetectable | 3ku1G-3cirB:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8k | PROTEIN PHOSPHATASE2C (Toxoplasmagondii) |
PF00481(PP2C) | 5 | GLY A 343VAL A 341ALA A 345GLY A 346ILE A 357 | None | 1.10A | 3ku1G-3d8kA:undetectable | 3ku1G-3d8kA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkh | LACCASE-1 (Melanocarpusalbomyces) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 500ASN A 147GLY A 146ALA A 559GLY A 558 | CU A 602 ( 4.9A)NoneNoneNoneNone | 1.19A | 3ku1G-3dkhA:undetectable | 3ku1G-3dkhA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga2 | ENDONUCLEASE V (Bacillussubtilis) |
PF04493(Endonuclease_5) | 5 | ARG A 214LEU A 215GLY A 117GLY A 127LEU A 148 | None | 1.06A | 3ku1G-3ga2A:undetectable | 3ku1G-3ga2A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcw | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | VAL A 284PRO A 282ALA A 409LEU A 415ILE A 334 | None | 0.80A | 3ku1G-3gcwA:2.2 | 3ku1G-3gcwA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gkb | PUTATIVE ENOYL-COAHYDRATASE (Streptomycesavermitilis) |
PF00378(ECH_1) | 5 | LEU A 111GLY A 139VAL A 170ALA A 115GLY A 119 | None | 1.14A | 3ku1G-3gkbA:undetectable | 3ku1G-3gkbA:25.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 11 | ARG A 15LEU A 16GLY A 33VAL A 57PRO A 61ASN A 84GLY A 85ALA A 101GLY A 102LEU A 107ILE A 111 | None | 0.42A | 3ku1G-3gnlA:31.8 | 3ku1G-3gnlA:42.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 8 | GLY A 33ASP A 35VAL A 57ASN A 84GLY A 85GLY A 102LEU A 107ILE A 111 | None | 0.77A | 3ku1G-3gnlA:31.8 | 3ku1G-3gnlA:42.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 5 | GLY A 55VAL A 57ASN A 84GLY A 85ILE A 111 | None | 1.03A | 3ku1G-3gnlA:31.8 | 3ku1G-3gnlA:42.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdl | ROYAL PALM TREEPEROXIDASE (Roystonea regia) |
PF00141(peroxidase) | 5 | LEU A 101GLY A 35GLY A 172ALA A 105ILE A 171 | NoneHEM A 305 ( 3.7A)HEM A 305 ( 3.2A)NoneEDO A 335 (-3.8A) | 0.99A | 3ku1G-3hdlA:undetectable | 3ku1G-3hdlA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihp | UBIQUITINCARBOXYL-TERMINALHYDROLASE 5 (Homo sapiens) |
PF00443(UCH)PF00627(UBA)PF02148(zf-UBP) | 5 | ARG A 352ASP A 567VAL A 570PRO A 566LEU A 344 | None | 1.12A | 3ku1G-3ihpA:undetectable | 3ku1G-3ihpA:13.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 9 | ARG A 5ASP A 25VAL A 47ASN A 74GLY A 75ALA A 91GLY A 92LEU A 97ILE A 101 | None | 0.73A | 3ku1G-3kr9A:34.9 | 3ku1G-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 9 | ARG A 5VAL A 47PRO A 51ASN A 74GLY A 75ALA A 91GLY A 92LEU A 97ILE A 101 | None | 0.64A | 3ku1G-3kr9A:34.9 | 3ku1G-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 9 | GLY A 23ASP A 25VAL A 47ASN A 74GLY A 75ALA A 91GLY A 92LEU A 97ILE A 101 | None | 0.60A | 3ku1G-3kr9A:34.9 | 3ku1G-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 5 | GLY A 45VAL A 47ASN A 74GLY A 75ILE A 101 | None | 1.05A | 3ku1G-3kr9A:34.9 | 3ku1G-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 10 | LEU A 6GLY A 23VAL A 47PRO A 51ASN A 74GLY A 75ALA A 91GLY A 92LEU A 97ILE A 101 | None | 0.50A | 3ku1G-3kr9A:34.9 | 3ku1G-3kr9A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8h | PUTATIVE HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bordetellabronchiseptica) |
PF13242(Hydrolase_like) | 5 | GLY A 138ALA A 140GLY A 120LEU A 3ILE A 5 | None | 1.08A | 3ku1G-3l8hA:2.2 | 3ku1G-3l8hA:23.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 8 | ARG A 8LEU A 9GLY A 26VAL A 50PRO A 54GLY A 78GLY A 95ILE A 104 | None | 0.51A | 3ku1G-3lecA:32.9 | 3ku1G-3lecA:61.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 8 | ARG A 8LEU A 9GLY A 26VAL A 50PRO A 54GLY A 95LEU A 100ILE A 104 | NoneNoneNoneNoneNoneNoneSO4 A 229 ( 4.7A)None | 0.54A | 3ku1G-3lecA:32.9 | 3ku1G-3lecA:61.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 5 | GLY A 26ASP A 28VAL A 50GLY A 78ILE A 104 | None | 0.84A | 3ku1G-3lecA:32.9 | 3ku1G-3lecA:61.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 5 | GLY A 26ASP A 28VAL A 50LEU A 100ILE A 104 | NoneNoneNoneSO4 A 229 ( 4.7A)None | 0.84A | 3ku1G-3lecA:32.9 | 3ku1G-3lecA:61.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n11 | CHITINASE A (Bacillus cereus) |
PF00704(Glyco_hydro_18) | 5 | VAL A 224ALA A 271GLY A 258LEU A 209ILE A 212 | None | 0.99A | 3ku1G-3n11A:undetectable | 3ku1G-3n11A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nv9 | MALIC ENZYME (Entamoebahistolytica) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 242ALA A 204GLY A 205LEU A 210ILE A 217 | None | 1.10A | 3ku1G-3nv9A:3.6 | 3ku1G-3nv9A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o2x | COLLAGENASE 3 (Homo sapiens) |
PF00413(Peptidase_M10) | 5 | LEU A1254GLY A1225GLY A1197LEU A1118ILE A1163 | None | 1.05A | 3ku1G-3o2xA:undetectable | 3ku1G-3o2xA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p02 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF14274(DUF4361)PF16343(DUF4973) | 5 | GLY A 315ASP A 292GLY A 184LEU A 206ILE A 204 | None | 1.13A | 3ku1G-3p02A:undetectable | 3ku1G-3p02A:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p4e | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Vibrio cholerae) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | ASP A 108ASN A 94ALA A 128GLY A 126ILE A 228 | AMP A 501 (-3.0A)NoneNoneNoneNone | 1.06A | 3ku1G-3p4eA:undetectable | 3ku1G-3p4eA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q7h | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Coxiellaburnetii) |
PF00574(CLP_protease) | 5 | LEU A 155GLY A 101ALA A 106GLY A 107LEU A 63 | None | 0.92A | 3ku1G-3q7hA:undetectable | 3ku1G-3q7hA:25.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | LEU C 317GLY C 280VAL C 257ALA C 277ILE C 274 | None | 0.96A | 3ku1G-3qgkC:undetectable | 3ku1G-3qgkC:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT JNADH-QUINONEOXIDOREDUCTASESUBUNIT KNADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli;Escherichiacoli;Escherichiacoli) |
no annotationno annotationno annotation | 5 | LEU N 176PRO K 3GLY J 9ALA K 12ILE J 13 | None | 0.90A | 3ku1G-3rkoN:undetectable | 3ku1G-3rkoN:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rnl | SULFOTRANSFERASE (Alicyclobacillusacidocaldarius) |
PF13469(Sulfotransfer_3) | 5 | GLY A 17ALA A 13GLY A 12LEU A 110ILE A 183 | NoneNoneNoneNoneGOL A 314 (-4.3A) | 0.99A | 3ku1G-3rnlA:undetectable | 3ku1G-3rnlA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3svt | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriumulcerans) |
PF13561(adh_short_C2) | 5 | VAL A 12ALA A 45GLY A 46LEU A 51ILE A 61 | None | 0.87A | 3ku1G-3svtA:6.6 | 3ku1G-3svtA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbh | O-ACETYL SERINESULFHYDRYLASE (Leishmaniadonovani) |
PF00291(PALP) | 5 | GLY A 188VAL A 236ALA A 183GLY A 184ILE A 245 | LLP A 51 ( 3.4A)NoneNoneNoneNone | 1.08A | 3ku1G-3tbhA:3.3 | 3ku1G-3tbhA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgl | GLUCOKINASE (Streptomycesgriseus) |
PF00480(ROK) | 5 | LEU A 88GLY A 10GLY A 133ALA A 64GLY A 63 | NoneANP A 325 (-3.4A)BGC A 324 ( 3.9A)NoneNone | 1.17A | 3ku1G-3vglA:undetectable | 3ku1G-3vglA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | GLY A2072ALA A2021GLY A2020LEU A2067ILE A2046 | None | 0.99A | 3ku1G-3vkgA:undetectable | 3ku1G-3vkgA:5.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4at0 | 3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE (Rhodococcusjostii) |
PF00890(FAD_binding_2) | 5 | LEU A 96GLY A 469VAL A 167GLY A 64GLY A 148 | NoneFAD A1493 ( 3.1A)NoneACT A1491 ( 3.2A)None | 0.88A | 3ku1G-4at0A:undetectable | 3ku1G-4at0A:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhi | GAMMA-BUTYROBETAINEDIOXYGENASE (Homo sapiens) |
PF02668(TauD)PF06155(DUF971) | 5 | LEU A 217ASP A 204PRO A 206GLY A 234GLY A 348 | None ZN A 402 (-2.6A)NoneNoneNone | 1.12A | 3ku1G-4bhiA:undetectable | 3ku1G-4bhiA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cr4 | 26S PROTEASEREGULATORY SUBUNIT 7HOMOLOG (Saccharomycescerevisiae) |
PF00004(AAA) | 5 | GLY H 255PRO H 251GLY H 212LEU H 419ILE H 388 | None | 0.99A | 3ku1G-4cr4H:undetectable | 3ku1G-4cr4H:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fo7 | METHIONINEAMINOPEPTIDASE (Pseudomonasaeruginosa) |
PF00557(Peptidase_M24) | 5 | GLY A 186ALA A 188GLY A 189LEU A 145ILE A 148 | None | 1.14A | 3ku1G-4fo7A:undetectable | 3ku1G-4fo7A:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kgb | SUCCINYL-COA:3-KETOACID-COENZYME ATRANSFERASE (Drosophilamelanogaster) |
PF01144(CoA_trans) | 5 | GLY A 420ASP A 424ASN A 361GLY A 363ILE A 319 | None | 1.18A | 3ku1G-4kgbA:undetectable | 3ku1G-4kgbA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lds | BICYCLOMYCINRESISTANCE PROTEINTCAB (Staphylococcusepidermidis) |
PF00083(Sugar_tr) | 5 | GLY A 63GLY A 111GLY A 70LEU A 77ILE A 78 | None | 0.95A | 3ku1G-4ldsA:undetectable | 3ku1G-4ldsA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | GLY A 192VAL A 218ALA A 188GLY A 214ILE A 207 | None | 1.03A | 3ku1G-4m7eA:undetectable | 3ku1G-4m7eA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m9p | FILAMIN-A (Homo sapiens) |
PF00630(Filamin) | 5 | ARG A 664GLY A 702GLY A 729GLY A 750LEU A 707 | None | 1.18A | 3ku1G-4m9pA:undetectable | 3ku1G-4m9pA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oal | CYTOKININDEHYDROGENASE 4 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 5 | PRO A 194GLY A 177GLY A 225LEU A 202ILE A 236 | NoneFAD A 601 (-3.5A)NoneNoneFAD A 601 (-3.9A) | 0.97A | 3ku1G-4oalA:undetectable | 3ku1G-4oalA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ov6 | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | VAL B 284PRO B 282ALA B 409LEU B 415ILE B 334 | None | 0.81A | 3ku1G-4ov6B:undetectable | 3ku1G-4ov6B:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxb | UREIDOGLYCOLATEHYDROLASE (Arabidopsisthaliana) |
PF01546(Peptidase_M20) | 5 | LEU A 73GLY A 156GLY A 462GLY A 150ILE A 440 | NoneNoneNone MN A 501 ( 4.0A)None | 0.93A | 3ku1G-4pxbA:undetectable | 3ku1G-4pxbA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyr | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A2905VAL A2657ALA A2552GLY A2551LEU A2641 | None | 0.75A | 3ku1G-4qyrA:undetectable | 3ku1G-4qyrA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rp8 | ASCORBATE-SPECIFICPERMEASE IICCOMPONENT ULAA (Escherichiacoli) |
PF03611(EIIC-GAT) | 5 | LEU A 23GLY A 193ASP A 314GLY A 171GLY A 134 | NoneNoneASC A 501 (-2.7A)NoneNone | 1.16A | 3ku1G-4rp8A:undetectable | 3ku1G-4rp8A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru5 | TAILSPIKE GP27 (Pseudomonasphage phi297) |
no annotation | 5 | GLY A 496ASP A 479GLY A 519GLY A 525ILE A 548 | None | 0.98A | 3ku1G-4ru5A:undetectable | 3ku1G-4ru5A:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4usc | PEROXIDASE (Trachycarpusfortunei) |
PF00141(peroxidase) | 5 | LEU A 101GLY A 35GLY A 172ALA A 105ILE A 171 | NoneHEM A1318 (-3.4A)HEM A1318 (-3.1A)NoneNone | 0.98A | 3ku1G-4uscA:undetectable | 3ku1G-4uscA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uz1 | NOTUM (Homo sapiens) |
PF03283(PAE) | 5 | LEU A 375GLY A 266GLY A 234GLY A 321LEU A 240 | None | 1.15A | 3ku1G-4uz1A:undetectable | 3ku1G-4uz1A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbh | PROTEIN NOTUMHOMOLOG (Homo sapiens) |
PF03283(PAE) | 5 | LEU A 375GLY A 266GLY A 234GLY A 321LEU A 240 | None | 1.11A | 3ku1G-4wbhA:undetectable | 3ku1G-4wbhA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwo | ORGANOPHOSPHATEANHYDROLASE/PROLIDASE (Alteromonas sp.) |
PF00557(Peptidase_M24) | 5 | LEU A 225GLY A 333GLY A 383LEU A 282ILE A 380 | None | 1.07A | 3ku1G-4zwoA:undetectable | 3ku1G-4zwoA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3y | THERMOLYSIN (Bacillusthermoproteolyticus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 5 | ASN A 60GLY A 8ALA A 68LEU A 30ILE A 20 | None | 1.13A | 3ku1G-5a3yA:undetectable | 3ku1G-5a3yA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITGAMMA (Methanothermobactermarburgensis) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 5 | PRO B 428GLY B 416ALA B 197LEU B 178ILE B 415 | None | 1.06A | 3ku1G-5a8rB:undetectable | 3ku1G-5a8rB:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b58 | PUTATIVE HEMIN ABCTRANSPORT SYSTEM,MEMBRANE PROTEIN (Burkholderiacenocepacia) |
PF01032(FecCD) | 5 | GLY A 94VAL A 275ALA A 316GLY A 315ILE A 285 | None | 1.11A | 3ku1G-5b58A:undetectable | 3ku1G-5b58A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey5 | LBCATS-A (syntheticconstruct) |
PF00290(Trp_syntA) | 5 | GLY A 26ASP A 29GLY A 51GLY A 75ILE A 52 | None | 1.18A | 3ku1G-5ey5A:undetectable | 3ku1G-5ey5A:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fif | CARBOXYLASE (Deinococcusradiodurans) |
PF01039(Carboxyl_trans) | 5 | GLY A 158ALA A 201GLY A 202LEU A 207ILE A 221 | None | 1.03A | 3ku1G-5fifA:undetectable | 3ku1G-5fifA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmr | INTRAFLAGELLARTRANSPORT PROTEINCOMPONENT IFT52 (Chlamydomonasreinhardtii) |
PF09822(ABC_transp_aux) | 5 | LEU A 91PRO A 182GLY A 141LEU A 177ILE A 142 | None | 1.07A | 3ku1G-5fmrA:2.1 | 3ku1G-5fmrA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fnx | POTATO STI-KUNITZBI-FUNCTIONALINHIBITOR E3AD_N19D (Solanumtuberosum) |
PF00197(Kunitz_legume) | 5 | LEU A 172GLY A 34VAL A 59PRO A 61GLY A 30 | None | 0.87A | 3ku1G-5fnxA:undetectable | 3ku1G-5fnxA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fxn | THERMOLYSIN (Bacillusthermoproteolyticus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 5 | ASN A 60GLY A 8ALA A 68LEU A 30ILE A 20 | None | 1.11A | 3ku1G-5fxnA:undetectable | 3ku1G-5fxnA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h6j | PIERISIN-1 (Pieris rapae) |
no annotation | 5 | LEU A 53GLY A 147ASP A 149GLY A 171ILE A 172 | None | 1.19A | 3ku1G-5h6jA:undetectable | 3ku1G-5h6jA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hax | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF08801(Nucleoporin_N) | 5 | LEU A 562GLY A 178ALA A 156LEU A 232ILE A 177 | None | 1.13A | 3ku1G-5haxA:undetectable | 3ku1G-5haxA:14.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihw | SERINE-ASPARTATEREPEAT-CONTAININGPROTEIN E (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 5 | ASN A 532ALA A 565GLY A 484LEU A 481ILE A 479 | None | 1.02A | 3ku1G-5ihwA:undetectable | 3ku1G-5ihwA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j84 | DIHYDROXY-ACIDDEHYDRATASE (Rhizobiumleguminosarum) |
PF00920(ILVD_EDD) | 5 | ARG A 289LEU A 566ALA A 106GLY A 137LEU A 50 | None | 1.00A | 3ku1G-5j84A:2.0 | 3ku1G-5j84A:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lhs | UROKINASE-TYPEPLASMINOGENACTIVATOR (Mus musculus) |
no annotation | 5 | GLY B 216ASP B 194GLY B 142GLY B 196LEU B 155 | None | 1.13A | 3ku1G-5lhsB:undetectable | 3ku1G-5lhsB:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqs | BETA-L-ARABINOBIOSIDASE (Bacteroidesthetaiotaomicron) |
PF13088(BNR_2) | 5 | ARG A1034PRO A 898ALA A 960LEU A 971ILE A 911 | None | 1.16A | 3ku1G-5mqsA:undetectable | 3ku1G-5mqsA:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t2h | I-ONUI_E-HTCRA (syntheticconstruct) |
PF00961(LAGLIDADG_1) | 5 | LEU A 99ALA A 19GLY A 23LEU A 49ILE A 56 | None | 1.12A | 3ku1G-5t2hA:undetectable | 3ku1G-5t2hA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCEMDCD (Pseudomonasaeruginosa;Pseudomonasaeruginosa) |
PF06833(MdcE)PF01039(Carboxyl_trans) | 5 | GLY B 182GLY B 162GLY A 110LEU A 115ILE B 165 | None | 0.90A | 3ku1G-5vipB:undetectable | 3ku1G-5vipB:27.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlh | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8)PF05922(Inhibitor_I9) | 5 | VAL A 284PRO A 282ALA A 409LEU A 415ILE A 334 | None | 0.75A | 3ku1G-5vlhA:undetectable | 3ku1G-5vlhA:20.60 |