SIMILAR PATTERNS OF AMINO ACIDS FOR 3KU1_C_SAMC226_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgm | ADENOSINE KINASE (Toxoplasmagondii) |
PF00294(PfkB) | 5 | GLY A 19GLY A 69ALA A 93LEU A 142ILE A 22 | CL A 385 ( 3.8A)ADN A 375 (-2.9A)NoneNoneADN A 375 ( 4.3A) | 0.94A | 3ku1C-1dgmA:3.1 | 3ku1C-1dgmA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ee1 | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Bacillussubtilis) |
PF02540(NAD_synthase) | 5 | PRO A 199ALA A 54GLY A 55LEU A 60ILE A 22 | None | 0.91A | 3ku1C-1ee1A:2.2 | 3ku1C-1ee1A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ep5 | CAPSID PROTEIN C (Venezuelanequineencephalitisvirus) |
no annotation | 5 | GLY B 243VAL B 255PRO B 269ALA B 222GLY B 221 | None | 0.92A | 3ku1C-1ep5B:undetectable | 3ku1C-1ep5B:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq1 | CYTOCHROME CD1NITRITE REDUCTASE (Paracoccuspantotrophus) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 5 | GLY A 239GLY A 138ALA A 260GLY A 261ILE A 281 | None | 0.84A | 3ku1C-1gq1A:undetectable | 3ku1C-1gq1A:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqb | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A1182GLY A1158ALA A1177GLY A1176ILE A1265 | None | 0.95A | 3ku1C-1jqbA:4.1 | 3ku1C-1jqbA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js4 | ENDO/EXOCELLULASE E4 (Thermobifidafusca) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | VAL A 364GLY A 400ALA A 431GLY A 432LEU A 437 | None | 0.82A | 3ku1C-1js4A:undetectable | 3ku1C-1js4A:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k72 | ENDOGLUCANASE 9G ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | VAL A 361GLY A 397ALA A 427GLY A 428LEU A 433 | None | 0.87A | 3ku1C-1k72A:undetectable | 3ku1C-1k72A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbv | MAJOR OUTER MEMBRANEPROTEIN PAN 1 (Neisseriagonorrhoeae) |
PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 5 | VAL A 266GLY A 269GLY A 129LEU A 151ILE A 132 | None | 0.87A | 3ku1C-1kbvA:undetectable | 3ku1C-1kbvA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 5 | GLY A 166GLY A 182ALA A 177GLY A 176LEU A 110 | None | 0.86A | 3ku1C-1kfwA:undetectable | 3ku1C-1kfwA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khd | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Pectobacteriumcarotovorum) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 5 | GLY A 191ALA A 66GLY A 67LEU A 72ILE A 194 | None | 0.80A | 3ku1C-1khdA:undetectable | 3ku1C-1khdA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks8 | ENDO-B-1,4-GLUCANASE (Nasutitermestakasagoensis) |
PF00759(Glyco_hydro_9) | 5 | VAL A 347GLY A 389ALA A 419GLY A 420LEU A 425 | None | 0.79A | 3ku1C-1ks8A:undetectable | 3ku1C-1ks8A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhy | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 5 | VAL B 254GLY B 251ALA B 230GLY B 229ILE B 237 | None | 0.92A | 3ku1C-1mhyB:undetectable | 3ku1C-1mhyB:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pq5 | TRYPSIN (Fusariumoxysporum) |
PF00089(Trypsin) | 5 | GLY A 229ASP A 126PRO A 127LEU A 100ILE A 235 | None | 0.95A | 3ku1C-1pq5A:undetectable | 3ku1C-1pq5A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sjp | 60 KDA CHAPERONIN 2 (Mycobacteriumtuberculosis) |
PF00118(Cpn60_TCP1) | 5 | ASP A 335GLY A 189ALA A 290GLY A 295ILE A 329 | None | 0.93A | 3ku1C-1sjpA:undetectable | 3ku1C-1sjpA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdf | THIOREDOXINREDUCTASE (Escherichiacoli) |
PF07992(Pyr_redox_2) | 5 | GLY A 285ASP A 289ALA A 299GLY A 300ILE A 109 | FAD A 500 (-3.1A)NoneNoneNoneNone | 0.90A | 3ku1C-1tdfA:5.4 | 3ku1C-1tdfA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz6 | PUTATIVE SUGARKINASE (Salmonellaenterica) |
PF00294(PfkB) | 5 | LEU A 62GLY A 11ASP A 108ALA A 34GLY A 31 | NoneNoneNoneNoneAIS A 402 (-3.8A) | 0.91A | 3ku1C-1tz6A:3.0 | 3ku1C-1tz6A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vdc | NADPH DEPENDENTTHIOREDOXINREDUCTASE (Arabidopsisthaliana) |
PF07992(Pyr_redox_2) | 5 | GLY A 285ASP A 289ALA A 299GLY A 300ILE A 109 | FAD A 400 ( 3.2A)NoneNoneNoneNone | 0.95A | 3ku1C-1vdcA:4.6 | 3ku1C-1vdcA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve1 | O-ACETYLSERINESULFHYDRYLASE (Thermusthermophilus) |
PF00291(PALP) | 5 | LEU A 234GLY A 173PRO A 201GLY A 177ILE A 39 | NoneNoneNonePLP A 413 (-3.8A)None | 0.90A | 3ku1C-1ve1A:2.1 | 3ku1C-1ve1A:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wls | L-ASPARAGINASE (Pyrococcushorikoshii) |
PF00710(Asparaginase) | 5 | GLY A 213VAL A 248GLY A 210LEU A 207ILE A 205 | None | 0.77A | 3ku1C-1wlsA:undetectable | 3ku1C-1wlsA:25.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zj9 | PROBABLEFERREDOXIN-DEPENDENTNITRITE REDUCTASENIRA (Mycobacteriumtuberculosis) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 6 | ARG A 304PRO A 233GLY A 229ALA A 259GLY A 258ILE A 228 | None | 1.14A | 3ku1C-1zj9A:undetectable | 3ku1C-1zj9A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a3k | PROTEIN TYROSINEPHOSPHATASE,NON-RECEPTOR TYPE 7,ISOFORM 1 (Homo sapiens) |
PF00102(Y_phosphatase) | 6 | GLY A 294VAL A 289GLY A 332MET A 333LEU A 326ILE A 155 | PO4 A 501 (-4.4A)NoneNoneNoneNoneNone | 1.34A | 3ku1C-2a3kA:undetectable | 3ku1C-2a3kA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a87 | THIOREDOXINREDUCTASE (Mycobacteriumtuberculosis) |
PF07992(Pyr_redox_2) | 5 | GLY A 287ASP A 291ALA A 301GLY A 302ILE A 119 | FAD A 348 (-3.2A)NoneNoneNoneNone | 0.91A | 3ku1C-2a87A:5.0 | 3ku1C-2a87A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8b | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE R (Homo sapiens) |
PF00102(Y_phosphatase) | 6 | GLY A 591VAL A 586GLY A 629MET A 630LEU A 623ILE A 452 | None | 1.29A | 3ku1C-2a8bA:undetectable | 3ku1C-2a8bA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buf | ACETYLGLUTAMATEKINASE (Pseudomonasaeruginosa) |
PF00696(AA_kinase) | 5 | LEU A 216GLY A 186ALA A 202GLY A 203ILE A 134 | None | 0.91A | 3ku1C-2bufA:3.6 | 3ku1C-2bufA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bv5 | TYROSINE-PROTEINPHOSPHATASE,NON-RECEPTOR TYPE 5 (Homo sapiens) |
PF00102(Y_phosphatase) | 6 | GLY A 475VAL A 470GLY A 513MET A 514LEU A 507ILE A 335 | SCY A 472 ( 3.6A)NoneNoneNoneNoneNone | 1.27A | 3ku1C-2bv5A:undetectable | 3ku1C-2bv5A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 5 | GLY A 961VAL A 986GLY A 964LEU A1025ILE A1066 | NoneNoneTPP A2236 (-3.2A)NoneNone | 0.91A | 3ku1C-2c3oA:undetectable | 3ku1C-2c3oA:10.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eid | GALACTOSE OXIDASE (Fusariumgraminearum) |
PF00754(F5_F8_type_C)PF01344(Kelch_1)PF09118(DUF1929) | 6 | GLY A 243ASP A 246VAL A 241GLY A 230ALA A 269MET A 266 | None | 1.29A | 3ku1C-2eidA:undetectable | 3ku1C-2eidA:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fx5 | LIPASE (Pseudomonasmendocina) |
no annotation | 5 | GLY A 131PRO A 149GLY A 155ALA A 135GLY A 136 | None | 0.90A | 3ku1C-2fx5A:2.7 | 3ku1C-2fx5A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gl5 | PUTATIVE DEHYDRATASEPROTEIN (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLY A 43GLY A 96ALA A 50GLY A 49ILE A 56 | None | 0.94A | 3ku1C-2gl5A:undetectable | 3ku1C-2gl5A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsn | PHOSPHODIESTERASE-NUCLEOTIDEPYROPHOSPHATASE (Xanthomonascitri) |
PF01663(Phosphodiest) | 5 | ARG A 243ALA A 239GLY A 240MET A 241ILE A 252 | None | 0.81A | 3ku1C-2gsnA:undetectable | 3ku1C-2gsnA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gtp | REGULATOR OFG-PROTEIN SIGNALING1 (Homo sapiens) |
PF00615(RGS) | 5 | GLY C 82GLY C 87ALA C 78LEU C 103ILE C 99 | None | 0.93A | 3ku1C-2gtpC:undetectable | 3ku1C-2gtpC:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hf7 | CLASS B ACIDPHOSPHATASE (Escherichiacoli) |
PF03767(Acid_phosphat_B) | 5 | LEU A 156ASP A 171GLY A 42LEU A 97ILE A 29 | None MG A 700 ( 4.5A)NoneNoneNone | 0.91A | 3ku1C-2hf7A:2.2 | 3ku1C-2hf7A:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hig | 6-PHOSPHO-1-FRUCTOKINASE (Trypanosomabrucei) |
PF00365(PFK) | 5 | GLY A 223VAL A 221GLY A 412GLY A 198ILE A 427 | None | 0.94A | 3ku1C-2higA:2.1 | 3ku1C-2higA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iex | DIHYDROXYNAPTHOICACID SYNTHETASE (Geobacilluskaustophilus) |
PF00378(ECH_1) | 5 | LEU A 194GLY A 66ALA A 114GLY A 115ILE A 27 | None | 0.91A | 3ku1C-2iexA:undetectable | 3ku1C-2iexA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3s | FILAMIN-A (Homo sapiens) |
PF00630(Filamin) | 5 | LEU A2162PRO A2181GLY A2237ALA A2266GLY A2267 | None | 0.79A | 3ku1C-2j3sA:undetectable | 3ku1C-2j3sA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jzj | CYANOVIRIN-N HOMOLOG (Ceratopterisrichardii) |
PF08881(CVNH) | 5 | GLY A 56GLY A 42GLY A 16LEU A 70ILE A 41 | None | 0.95A | 3ku1C-2jzjA:undetectable | 3ku1C-2jzjA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lfu | GNA2132 (Neisseriameningitidis) |
PF01298(TbpB_B_D) | 5 | VAL A 401GLY A 376ALA A 314GLY A 315ILE A 372 | None | 0.83A | 3ku1C-2lfuA:undetectable | 3ku1C-2lfuA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlx | XYLULOSE KINASE (Escherichiacoli) |
PF00370(FGGY_N)PF02782(FGGY_C) | 6 | LEU A 281GLY A 237VAL A 422GLY A 242LEU A 449ILE A 393 | None | 1.38A | 3ku1C-2nlxA:undetectable | 3ku1C-2nlxA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ols | PHOSPHOENOLPYRUVATESYNTHASE (Neisseriameningitidis) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | ARG A 321ASP A 286PRO A 283ALA A 200GLY A 199 | None | 0.77A | 3ku1C-2olsA:undetectable | 3ku1C-2olsA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ols | PHOSPHOENOLPYRUVATESYNTHASE (Neisseriameningitidis) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | ARG A 321VAL A 280PRO A 283ALA A 200GLY A 199 | None | 0.88A | 3ku1C-2olsA:undetectable | 3ku1C-2olsA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5u | UDP-GLUCOSE4-EPIMERASE (Thermusthermophilus) |
PF01370(Epimerase) | 5 | GLY A 175GLY A 299ALA A 188GLY A 185ILE A 300 | None | 0.94A | 3ku1C-2p5uA:5.1 | 3ku1C-2p5uA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qru | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF07859(Abhydrolase_3) | 5 | LEU A 48GLY A 231GLY A 100LEU A 109ILE A 230 | None | 0.95A | 3ku1C-2qruA:undetectable | 3ku1C-2qruA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8w | AGR_C_1641P (Agrobacteriumfabrum) |
PF00701(DHDPS) | 5 | GLY A 221ALA A 204GLY A 205LEU A 210ILE A 220 | None | 0.85A | 3ku1C-2r8wA:undetectable | 3ku1C-2r8wA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2raa | PYRUVATE SYNTHASESUBUNIT PORC (Thermotogamaritima) |
PF01558(POR) | 5 | GLY A 14ASP A 80VAL A 77ALA A 16GLY A 17 | NoneNoneNoneSO4 A 193 ( 4.9A)SO4 A 193 (-3.2A) | 0.87A | 3ku1C-2raaA:undetectable | 3ku1C-2raaA:25.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rij | PUTATIVE2,3,4,5-TETRAHYDROPYRIDINE-2-CARBOXYLATEN-SUCCINYLTRANSFERASE (Campylobacterjejuni) |
PF14602(Hexapep_2)PF14789(THDPS_M)PF14790(THDPS_N) | 5 | GLY A 252VAL A 266GLY A 249ALA A 233GLY A 234 | None | 0.91A | 3ku1C-2rijA:undetectable | 3ku1C-2rijA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vfw | SHORT-CHAINZ-ISOPRENYLDIPHOSPHATESYNTHETASE (Mycobacteriumtuberculosis) |
PF01255(Prenyltransf) | 6 | LEU A 222GLY A 124GLY A 127ALA A 155LEU A 137ILE A 129 | None | 1.33A | 3ku1C-2vfwA:3.2 | 3ku1C-2vfwA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3c | GENERAL VESICULARTRANSPORT FACTORP115 (Homo sapiens) |
PF04869(Uso1_p115_head) | 5 | LEU A 171GLY A 142GLY A 80LEU A 69ILE A 79 | None | 0.90A | 3ku1C-2w3cA:undetectable | 3ku1C-2w3cA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfg | ENDOGLUCANASE 1 (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 5 | VAL A 364GLY A 400ALA A 430GLY A 431LEU A 436 | None | 0.92A | 3ku1C-2xfgA:undetectable | 3ku1C-2xfgA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 5 | GLY A 186GLY A 644ALA A 673GLY A 674ILE A 655 | None | 0.94A | 3ku1C-2xvgA:undetectable | 3ku1C-2xvgA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxl | 450AA LONGHYPOTHETICAL FMUPROTEIN (Pyrococcushorikoshii) |
PF01189(Methyltr_RsmB-F)PF17125(Methyltr_RsmF_N) | 5 | PRO A 314GLY A 272GLY A 308MET A 307ILE A 242 | NoneSFG A5748 (-3.7A)NoneNoneNone | 0.93A | 3ku1C-2yxlA:10.9 | 3ku1C-2yxlA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzg | ALANYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF01411(tRNA-synt_2c)PF07973(tRNA_SAD) | 5 | ARG A 625GLY A 696GLY A 621MET A 620LEU A 645 | None | 0.95A | 3ku1C-2zzgA:undetectable | 3ku1C-2zzgA:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3baz | HYDROXYPHENYLPYRUVATE REDUCTASE (Plectranthusscutellarioides) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 241VAL A 147ALA A 253GLY A 252LEU A 116 | None | 0.90A | 3ku1C-3bazA:5.1 | 3ku1C-3bazA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bdv | UNCHARACTERIZEDPROTEIN DUF1234 (Pectobacteriumatrosepticum) |
PF06821(Ser_hydrolase) | 5 | ARG A 9GLY A 100ALA A 180LEU A 17ILE A 76 | EDO A 196 (-3.8A)NoneNoneNoneNone | 0.95A | 3ku1C-3bdvA:2.2 | 3ku1C-3bdvA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bj1 | HEMOGLOBIN ALPHAHEMOGLOBIN BETA (Percaflavescens;Percaflavescens) |
PF00042(Globin)PF00042(Globin) | 5 | GLY A 30VAL A 35GLY B 124ALA A 26GLY A 25 | None | 0.90A | 3ku1C-3bj1A:undetectable | 3ku1C-3bj1A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cj8 | 2,3,4,5-TETRAHYDROPYRIDINE-2,6-DICARBOXYLATEN-ACETYLTRANSFERASE (Enterococcusfaecalis) |
PF00132(Hexapep)PF08503(DapH_N)PF14602(Hexapep_2) | 5 | GLY A 172VAL A 189ALA A 147GLY A 148LEU A 151 | NoneNoneNone MG A 301 ( 4.3A)None | 0.90A | 3ku1C-3cj8A:undetectable | 3ku1C-3cj8A:25.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8x | THIOREDOXINREDUCTASE 1 (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 5 | GLY A 287ASP A 291ALA A 301GLY A 302ILE A 116 | FAD A1001 (-3.5A)NoneNoneNoneNone | 0.95A | 3ku1C-3d8xA:5.2 | 3ku1C-3d8xA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3das | PUTATIVEOXIDOREDUCTASE (Streptomycescoelicolor) |
PF07995(GSDH) | 5 | GLY A 206PRO A 265GLY A 156ALA A 208ILE A 176 | None | 0.95A | 3ku1C-3dasA:undetectable | 3ku1C-3dasA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dj4 | BIFUNCTIONAL PROTEINGLMU (Mycobacteriumtuberculosis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 118VAL A 224ALA A 182GLY A 183ILE A 153 | NoneNoneNoneUD1 A4000 ( 4.5A)None | 0.92A | 3ku1C-3dj4A:2.2 | 3ku1C-3dj4A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ds8 | LIN2722 PROTEIN (Listeriainnocua) |
PF06028(DUF915) | 5 | GLY A 105VAL A 128GLY A 98GLY A 11LEU A 19 | NoneNoneNoneSO4 A 256 ( 3.5A)None | 0.80A | 3ku1C-3ds8A:2.5 | 3ku1C-3ds8A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbs | OXIDOREDUCTASE (Agrobacteriumfabrum) |
PF07992(Pyr_redox_2) | 5 | ARG A 289GLY A 280GLY A 14ALA A 285ILE A 7 | None | 0.88A | 3ku1C-3fbsA:2.6 | 3ku1C-3fbsA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcw | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | VAL A 284PRO A 282ALA A 409LEU A 415ILE A 334 | None | 0.84A | 3ku1C-3gcwA:2.7 | 3ku1C-3gcwA:18.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 11 | ARG A 15LEU A 16GLY A 33VAL A 57PRO A 61GLY A 85ALA A 101GLY A 102MET A 103LEU A 107ILE A 111 | None | 0.29A | 3ku1C-3gnlA:31.7 | 3ku1C-3gnlA:42.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 6 | GLY A 33ASP A 35GLY A 85MET A 103LEU A 107ILE A 111 | None | 1.14A | 3ku1C-3gnlA:31.7 | 3ku1C-3gnlA:42.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 7 | LEU A 39GLY A 33PRO A 61ALA A 101MET A 103LEU A 107ILE A 111 | None | 1.43A | 3ku1C-3gnlA:31.7 | 3ku1C-3gnlA:42.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjp | PEROXIREDOXIN,BACTERIOFERRITINCOMIGRATORY PROTEINHOMOLOG (BCP-4) (Sulfolobussolfataricus) |
PF00578(AhpC-TSA) | 5 | LEU A 108PRO A 143GLY A 68ALA A 39ILE A 90 | NoneNoneNone CL A 700 ( 4.6A)None | 0.95A | 3ku1C-3hjpA:undetectable | 3ku1C-3hjpA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isl | PURINE CATABOLISMPROTEIN PUCG (Bacillussubtilis) |
PF00266(Aminotran_5) | 5 | GLY A 312ALA A 383GLY A 384LEU A 389ILE A 396 | None | 0.90A | 3ku1C-3islA:3.7 | 3ku1C-3islA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jy6 | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Lactobacillusbrevis) |
PF13407(Peripla_BP_4) | 5 | VAL A 148PRO A 161GLY A 126ALA A 312GLY A 313 | None | 0.92A | 3ku1C-3jy6A:2.4 | 3ku1C-3jy6A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9b | LIVERCARBOXYLESTERASE 1 (Homo sapiens) |
PF00135(COesterase) | 5 | LEU A1472GLY A1224VAL A1229GLY A1141LEU A1144 | NoneNoneNoneWW2 A 193 (-3.8A)None | 0.95A | 3ku1C-3k9bA:2.8 | 3ku1C-3k9bA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq4 | CUBILIN (Homo sapiens) |
PF00431(CUB) | 6 | LEU B1085ASP B1111PRO B1118GLY B1167LEU B1195ILE B1257 | NoneNoneNoneNAG B2007 ( 3.9A)NoneNone | 1.24A | 3ku1C-3kq4B:undetectable | 3ku1C-3kq4B:15.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 10 | ARG A 5GLY A 23VAL A 47PRO A 51GLY A 75ALA A 91GLY A 92MET A 93LEU A 97ILE A 101 | None | 0.66A | 3ku1C-3kr9A:34.8 | 3ku1C-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 8 | GLY A 23ASP A 25GLY A 75ALA A 91GLY A 92MET A 93LEU A 97ILE A 101 | None | 1.01A | 3ku1C-3kr9A:34.8 | 3ku1C-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 10 | LEU A 6GLY A 23VAL A 47PRO A 51GLY A 75ALA A 91GLY A 92MET A 93LEU A 97ILE A 101 | None | 0.43A | 3ku1C-3kr9A:34.8 | 3ku1C-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 6 | LEU A 29PRO A 51ALA A 91MET A 93LEU A 97ILE A 101 | None | 1.47A | 3ku1C-3kr9A:34.8 | 3ku1C-3kr9A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 10 | ARG A 8LEU A 9GLY A 26VAL A 50PRO A 54GLY A 78GLY A 95MET A 96LEU A 100ILE A 104 | NoneNoneNoneNoneNoneNoneNoneNoneSO4 A 229 ( 4.7A)None | 0.51A | 3ku1C-3lecA:32.8 | 3ku1C-3lecA:61.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lec | NADB-ROSSMANNSUPERFAMILY PROTEIN (Streptococcusagalactiae) |
PF04816(TrmK) | 6 | GLY A 26ASP A 28GLY A 78MET A 96LEU A 100ILE A 104 | NoneNoneNoneNoneSO4 A 229 ( 4.7A)None | 1.23A | 3ku1C-3lecA:32.8 | 3ku1C-3lecA:61.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mc1 | PREDICTEDPHOSPHATASE, HADFAMILY (Clostridiumacetobutylicum) |
PF13419(HAD_2) | 5 | GLY A 164ASP A 8VAL A 170GLY A 186ILE A 201 | None NA A 301 (-3.1A)NoneNoneNone | 0.94A | 3ku1C-3mc1A:undetectable | 3ku1C-3mc1A:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q7h | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Coxiellaburnetii) |
PF00574(CLP_protease) | 5 | LEU A 155GLY A 101ALA A 106GLY A 107LEU A 63 | None | 0.94A | 3ku1C-3q7hA:undetectable | 3ku1C-3q7hA:25.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT JNADH-QUINONEOXIDOREDUCTASESUBUNIT KNADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli;Escherichiacoli;Escherichiacoli) |
no annotationno annotationno annotation | 5 | LEU N 176PRO K 3GLY J 9ALA K 12ILE J 13 | None | 0.90A | 3ku1C-3rkoN:undetectable | 3ku1C-3rkoN:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3svt | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriumulcerans) |
PF13561(adh_short_C2) | 5 | VAL A 12ALA A 45GLY A 46LEU A 51ILE A 61 | None | 0.91A | 3ku1C-3svtA:6.9 | 3ku1C-3svtA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ts7 | GERANYLTRANSTRANSFERASE (Methylococcuscapsulatus) |
PF00348(polyprenyl_synt) | 5 | ARG A 100GLY A 220MET A 51LEU A 55ILE A 190 | PO4 A 324 (-3.8A)NonePO4 A 323 (-3.8A)NoneNone | 0.88A | 3ku1C-3ts7A:undetectable | 3ku1C-3ts7A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgl | GLUCOKINASE (Streptomycesgriseus) |
PF00480(ROK) | 5 | LEU A 88GLY A 10GLY A 131ALA A 64GLY A 63 | NoneANP A 325 (-3.4A)ANP A 325 (-3.0A)NoneNone | 0.89A | 3ku1C-3vglA:undetectable | 3ku1C-3vglA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | GLY A2072ALA A2021GLY A2020LEU A2067ILE A2046 | None | 0.94A | 3ku1C-3vkgA:undetectable | 3ku1C-3vkgA:5.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 5 | ARG A 815LEU A 721VAL A 612ALA A 618GLY A 619 | None | 0.93A | 3ku1C-3w9hA:undetectable | 3ku1C-3w9hA:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsu | BETA-MANNANASE (Streptomycesthermolilacinus) |
PF00150(Cellulase) | 5 | LEU A 129ASP A 90GLY A 328ALA A 96GLY A 95 | None | 0.92A | 3ku1C-3wsuA:undetectable | 3ku1C-3wsuA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4at0 | 3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE (Rhodococcusjostii) |
PF00890(FAD_binding_2) | 6 | LEU A 96GLY A 469VAL A 167GLY A 64ALA A 467GLY A 148 | NoneFAD A1493 ( 3.1A)NoneACT A1491 ( 3.2A)NoneNone | 1.19A | 3ku1C-4at0A:undetectable | 3ku1C-4at0A:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4doe | 1,4-BETA-GLUCANASE (Caldicellulosiruptorbescii) |
PF00759(Glyco_hydro_9) | 5 | VAL A 384GLY A 420ALA A 450GLY A 451LEU A 456 | None | 0.86A | 3ku1C-4doeA:undetectable | 3ku1C-4doeA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fk9 | CELLULOSE-BINDINGFAMILY II (Streptomycessp. SirexAA-E) |
PF00150(Cellulase) | 5 | LEU A 129ASP A 90GLY A 328ALA A 96GLY A 95 | None | 0.95A | 3ku1C-4fk9A:undetectable | 3ku1C-4fk9A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jnq | THIOREDOXINREDUCTASE (Brucellamelitensis) |
PF07992(Pyr_redox_2) | 5 | GLY A 285ASP A 289ALA A 299GLY A 300ILE A 110 | FDA A 401 (-3.4A)NoneNoneNoneNone | 0.90A | 3ku1C-4jnqA:4.6 | 3ku1C-4jnqA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7g | 3-HYDROXYPROLINEDEHYDRATSE (Agrobacteriumvitis) |
PF05544(Pro_racemase) | 5 | GLY B 171ASP B 172PRO B 87ALA B 262GLY B 259 | NoneACT B 902 (-3.5A)NoneNoneNone | 0.91A | 3ku1C-4k7gB:undetectable | 3ku1C-4k7gB:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgl | GLYCINEDEHYDROGENASE[DECARBOXYLATING] (Synechocystissp. PCC 6803) |
PF02347(GDC-P) | 6 | LEU A 234GLY A 317ALA A 173GLY A 170LEU A 167ILE A 352 | None | 1.32A | 3ku1C-4lglA:undetectable | 3ku1C-4lglA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ov6 | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | VAL B 284PRO B 282ALA B 409LEU B 415ILE B 334 | None | 0.85A | 3ku1C-4ov6B:undetectable | 3ku1C-4ov6B:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q3n | MGS-M5 (unidentified) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ASP A 35VAL A 8GLY A 43LEU A 48ILE A 61 | None | 0.86A | 3ku1C-4q3nA:5.7 | 3ku1C-4q3nA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qez | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Bacillusanthracis) |
no annotation | 5 | ASP B 122PRO B 189ALA B 129LEU B 227ILE B 223 | None | 0.93A | 3ku1C-4qezB:undetectable | 3ku1C-4qezB:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyr | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A2905VAL A2657ALA A2552GLY A2551LEU A2641 | None | 0.80A | 3ku1C-4qyrA:undetectable | 3ku1C-4qyrA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uar | PROTEIN CBBY (Rhodobactersphaeroides) |
PF13419(HAD_2) | 5 | GLY A 219ALA A 215GLY A 96LEU A 174ILE A 192 | None | 0.91A | 3ku1C-4uarA:undetectable | 3ku1C-4uarA:24.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uz1 | NOTUM (Homo sapiens) |
PF03283(PAE) | 6 | GLY A 266ASP A 264VAL A 334GLY A 321ALA A 233GLY A 234 | None | 1.31A | 3ku1C-4uz1A:undetectable | 3ku1C-4uz1A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkq | NICKEL ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Staphylococcusaureus) |
PF00496(SBP_bac_5) | 5 | LEU A 52VAL A 29GLY A 154LEU A 169ILE A 158 | None | 0.87A | 3ku1C-4xkqA:undetectable | 3ku1C-4xkqA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg8 | ENDOGLUCANASE (Perinereisbrevicirris) |
PF00759(Glyco_hydro_9) | 5 | VAL A 349GLY A 391ALA A 421GLY A 422LEU A 427 | None | 0.87A | 3ku1C-4zg8A:undetectable | 3ku1C-4zg8A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoh | PUTATIVEOXIDOREDUCTASEMOLYBDOPTERIN-BINDING SUBUNIT (Sulfurisphaeratokodaii) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | ARG A 336GLY A 216GLY A 253ALA A 334GLY A 333 | None MO A 802 ( 3.9A)NoneNoneNone | 0.89A | 3ku1C-4zohA:undetectable | 3ku1C-4zohA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c5g | SPHERULIN-4 (Aspergillusclavatus) |
PF12138(Spherulin4) | 5 | GLY A 162ASP A 196VAL A 199GLY A 192ILE A 143 | None | 0.86A | 3ku1C-5c5gA:undetectable | 3ku1C-5c5gA:22.43 |