SIMILAR PATTERNS OF AMINO ACIDS FOR 3KP6_B_SALB3006
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bd2 | T CELL RECEPTORALPHA (Homo sapiens) |
PF07686(V-set)PF09291(DUF1968) | 4 | ASN D 117ILE D 118GLU D 14ASN D 115 | None | 1.37A | 3kp6A-1bd2D:undetectable3kp6B-1bd2D:0.0 | 3kp6A-1bd2D:21.463kp6B-1bd2D:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6s | O-ACETYLSERINESULFHYDRYLASE (Salmonellaenterica) |
PF00291(PALP) | 4 | ASN A 47MET A 48GLU A 150ASN A 148 | None | 1.38A | 3kp6A-1d6sA:0.03kp6B-1d6sA:0.0 | 3kp6A-1d6sA:19.883kp6B-1d6sA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0y | INTERLEUKIN-1RECEPTOR, TYPE I (Homo sapiens) |
PF07679(I-set)PF13895(Ig_2) | 4 | ILE R 14GLU R 11LYS R 12ASN R 216 | None | 1.40A | 3kp6A-1g0yR:undetectable3kp6B-1g0yR:0.0 | 3kp6A-1g0yR:19.873kp6B-1g0yR:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hml | ALPHA-LACTALBUMIN (Homo sapiens) |
PF00062(Lys) | 4 | ASN A 44GLU A 49LYS A 58ASN A 57 | None ZN A 125 ( 2.1A)NoneNone | 1.43A | 3kp6A-1hmlA:undetectable3kp6B-1hmlA:0.4 | 3kp6A-1hmlA:25.863kp6B-1hmlA:25.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1noz | DNA POLYMERASE (Escherichiavirus T4) |
PF03104(DNA_pol_B_exo1) | 4 | ASN A 23ILE A 20GLU A 22LYS A 2 | None | 1.32A | 3kp6A-1nozA:0.33kp6B-1nozA:0.0 | 3kp6A-1nozA:16.843kp6B-1nozA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p9b | ADENYLOSUCCINATESYNTHETASE (Plasmodiumfalciparum) |
PF00709(Adenylsucc_synt) | 4 | ASN A 217ILE A 262GLU A 221ASN A 219 | None | 1.05A | 3kp6A-1p9bA:0.03kp6B-1p9bA:0.0 | 3kp6A-1p9bA:15.873kp6B-1p9bA:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvh | INTERLEUKIN-6RECEPTOR BETA CHAIN (Homo sapiens) |
PF00041(fn3)PF09240(IL6Ra-bind) | 4 | ASN A 201GLU A 116LYS A 199ASN A 115 | None | 1.46A | 3kp6A-1pvhA:undetectable3kp6B-1pvhA:0.0 | 3kp6A-1pvhA:22.483kp6B-1pvhA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wop | AMINOMETHYLTRANSFERASE (Thermotogamaritima) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | ASN A 248ILE A 93GLU A 251ASN A 246 | None | 1.36A | 3kp6A-1wopA:0.03kp6B-1wopA:0.0 | 3kp6A-1wopA:17.813kp6B-1wopA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wxf | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Escherichiacoli) |
PF02540(NAD_synthase) | 4 | ASN A 188ILE A 17GLU A 239LYS A 14 | None | 1.48A | 3kp6A-1wxfA:0.03kp6B-1wxfA:0.0 | 3kp6A-1wxfA:22.943kp6B-1wxfA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fko | 173AA LONGHYPOTHETICALFERRIPYOCHELINBINDING PROTEIN (Pyrococcushorikoshii) |
PF00132(Hexapep) | 4 | ILE A 26GLU A 5LYS A 9ASN A 7 | None | 1.49A | 3kp6A-2fkoA:undetectable3kp6B-2fkoA:undetectable | 3kp6A-2fkoA:23.813kp6B-2fkoA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g8s | GLUCOSE/SORBOSONEDEHYDROGENASES (Escherichiacoli) |
PF07995(GSDH) | 4 | ASN A 222ILE A 193GLU A 220ASN A 211 | CA A2002 ( 4.4A)None CA A2002 (-2.2A)None | 1.15A | 3kp6A-2g8sA:undetectable3kp6B-2g8sA:undetectable | 3kp6A-2g8sA:18.803kp6B-2g8sA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gw1 | MITOCHONDRIALPRECURSOR PROTEINSIMPORT RECEPTOR (Saccharomycescerevisiae) |
PF00515(TPR_1)PF13181(TPR_8)PF13432(TPR_16) | 4 | ASN A 210GLU A 177LYS A 181ASN A 176 | None | 1.47A | 3kp6A-2gw1A:0.03kp6B-2gw1A:undetectable | 3kp6A-2gw1A:16.963kp6B-2gw1A:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrj | HBL B PROTEIN (Bacillus cereus) |
PF05791(Bacillus_HBL) | 4 | ASN A 260ILE A 153GLU A 261ASN A 258 | None | 1.33A | 3kp6A-2nrjA:0.93kp6B-2nrjA:0.5 | 3kp6A-2nrjA:19.583kp6B-2nrjA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbg | 6-PHOSPHO-BETA-D-GALACTOSIDASE (Lactococcuslactis) |
PF00232(Glyco_hydro_1) | 4 | ASN A 297ILE A 296GLU A 375ASN A 376 | None | 1.38A | 3kp6A-2pbgA:0.03kp6B-2pbgA:undetectable | 3kp6A-2pbgA:16.023kp6B-2pbgA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhh | CG3027-PA (Drosophilamelanogaster) |
PF00795(CN_hydrolase) | 4 | ASN A 187MET A 161ILE A 115GLU A 225 | None | 1.46A | 3kp6A-2vhhA:undetectable3kp6B-2vhhA:undetectable | 3kp6A-2vhhA:15.663kp6B-2vhhA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vim | THIOREDOXIN (Fasciolahepatica) |
PF00085(Thioredoxin) | 4 | ASN A 17ILE A 22GLU A 16ASN A 15 | None | 1.38A | 3kp6A-2vimA:undetectable3kp6B-2vimA:undetectable | 3kp6A-2vimA:21.053kp6B-2vimA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3be7 | ZN-DEPENDENTARGININECARBOXYPEPTIDASE (unidentified) |
PF01979(Amidohydro_1) | 4 | ASN A 379ILE A 380GLU A 374ASN A 375 | None | 1.34A | 3kp6A-3be7A:0.03kp6B-3be7A:undetectable | 3kp6A-3be7A:21.293kp6B-3be7A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3beo | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Bacillusanthracis) |
PF02350(Epimerase_2) | 4 | ASN A 220MET A 221ILE A 328ASN A 213 | None | 1.43A | 3kp6A-3beoA:undetectable3kp6B-3beoA:undetectable | 3kp6A-3beoA:17.663kp6B-3beoA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5e | PLATELET-ACTIVATINGFACTORACETYLHYDROLASE (Homo sapiens) |
PF03403(PAF-AH_p_II) | 4 | ASN A 421ILE A 422GLU A 320ASN A 318 | None | 1.13A | 3kp6A-3d5eA:undetectable3kp6B-3d5eA:undetectable | 3kp6A-3d5eA:18.233kp6B-3d5eA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3exs | RMPD(HEXULOSE-6-PHOSPHATE SYNTHASE) (Streptococcusmutans) |
PF00215(OMPdecase) | 4 | ILE A 60GLU A 113LYS A 111ASN A 108 | None | 1.40A | 3kp6A-3exsA:undetectable3kp6B-3exsA:undetectable | 3kp6A-3exsA:23.013kp6B-3exsA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f1c | PUTATIVE2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATECYTIDYLYLTRANSFERASE2 (Listeriamonocytogenes) |
PF01128(IspD) | 4 | ASN A 43ILE A 2GLU A 122ASN A 124 | None | 1.02A | 3kp6A-3f1cA:undetectable3kp6B-3f1cA:undetectable | 3kp6A-3f1cA:22.133kp6B-3f1cA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq9 | PRENECK APPENDAGEPROTEIN (Bacillus virusphi29) |
PF11962(Peptidase_G2)PF12708(Pectate_lyase_3) | 4 | ASN A 189ILE A 190GLU A 188ASN A 266 | None | 1.16A | 3kp6A-3gq9A:undetectable3kp6B-3gq9A:undetectable | 3kp6A-3gq9A:13.493kp6B-3gq9A:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmq | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Salmonellaenterica) |
PF02540(NAD_synthase) | 4 | ASN A 188ILE A 17GLU A 239LYS A 14 | None | 1.39A | 3kp6A-3hmqA:undetectable3kp6B-3hmqA:undetectable | 3kp6A-3hmqA:20.283kp6B-3hmqA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6o | UNCHARACTERIZEDPROTEIN DUF1344 (Bacteroidesvulgatus) |
PF12667(NigD_N)PF17415(NigD_C) | 4 | ASN A 114ILE A 121GLU A 160ASN A 159 | NoneNonePG4 A 1 (-3.2A)None | 1.19A | 3kp6A-3k6oA:undetectable3kp6B-3k6oA:undetectable | 3kp6A-3k6oA:21.033kp6B-3k6oA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6o | UNCHARACTERIZEDPROTEIN DUF1344 (Bacteroidesvulgatus) |
PF12667(NigD_N)PF17415(NigD_C) | 4 | MET A 118ILE A 121GLU A 160ASN A 159 | NoneNonePG4 A 1 (-3.2A)None | 1.15A | 3kp6A-3k6oA:undetectable3kp6B-3k6oA:undetectable | 3kp6A-3k6oA:21.033kp6B-3k6oA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk7 | UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATELIGASE (Streptococcusagalactiae) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | ASN A 297ILE A 287GLU A 264ASN A 265 | SO4 A 453 (-3.5A)NoneNoneNone | 0.76A | 3kp6A-3lk7A:undetectable3kp6B-3lk7A:undetectable | 3kp6A-3lk7A:15.933kp6B-3lk7A:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m0e | TRANSCRIPTIONALREGULATOR (NTRCFAMILY) (Aquifexaeolicus) |
PF00158(Sigma54_activat) | 4 | ASN A 355ILE A 307GLU A 168ASN A 280 | NoneNoneNoneATP A 400 (-4.2A) | 1.32A | 3kp6A-3m0eA:undetectable3kp6B-3m0eA:undetectable | 3kp6A-3m0eA:22.513kp6B-3m0eA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3me5 | CYTOSINE-SPECIFICMETHYLTRANSFERASE (Shigellaflexneri) |
PF00145(DNA_methylase) | 4 | ASN A 43ILE A 49GLU A 67ASN A 38 | None | 1.32A | 3kp6A-3me5A:undetectable3kp6B-3me5A:undetectable | 3kp6A-3me5A:18.583kp6B-3me5A:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otm | CARBONIC ANHYDRASE (Methanosarcinathermophila) |
PF00132(Hexapep)PF14602(Hexapep_2) | 4 | MET A 64ILE A 66GLU A 62ASN A 14 | None | 1.40A | 3kp6A-3otmA:undetectable3kp6B-3otmA:undetectable | 3kp6A-3otmA:20.003kp6B-3otmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qor | NUCLEAR MIGRATIONPROTEIN NUDC (Homo sapiens) |
PF04969(CS) | 4 | ASN A 224ILE A 248GLU A 252LYS A 250 | NoneACT A 301 ( 4.5A)NoneNone | 1.13A | 3kp6A-3qorA:undetectable3kp6B-3qorA:undetectable | 3kp6A-3qorA:23.423kp6B-3qorA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3skp | SEROTRANSFERRIN (Homo sapiens) |
PF00405(Transferrin) | 4 | ASN A 383MET A 382ILE A 381GLU A 385 | None | 1.48A | 3kp6A-3skpA:0.93kp6B-3skpA:undetectable | 3kp6A-3skpA:17.663kp6B-3skpA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq4 | BETA-PRIMEVEROSIDASE (Camelliasinensis) |
PF00232(Glyco_hydro_1) | 4 | ASN A 202MET A 201ILE A 199GLU A 203 | None | 1.22A | 3kp6A-3wq4A:undetectable3kp6B-3wq4A:undetectable | 3kp6A-3wq4A:14.653kp6B-3wq4A:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 4 | ASN A 399MET A 405ILE A 400ASN A 417 | None | 1.46A | 3kp6A-3zuqA:2.13kp6B-3zuqA:1.5 | 3kp6A-3zuqA:11.263kp6B-3zuqA:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxw | FACTOR XA (Pseudonajatextilis) |
PF00089(Trypsin)PF14670(FXa_inhibition) | 4 | ASN A 95ILE A 107LYS A 89ASN A 93 | None | 1.42A | 3kp6A-4bxwA:undetectable3kp6B-4bxwA:undetectable | 3kp6A-4bxwA:16.163kp6B-4bxwA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c8q | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 4 | ASN H 687MET H 691ILE H 690GLU H 701 | NoneNoneNone CO H1080 (-3.8A) | 1.26A | 3kp6A-4c8qH:undetectable3kp6B-4c8qH:undetectable | 3kp6A-4c8qH:19.213kp6B-4c8qH:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dqn | PUTATIVEBRANCHED-CHAIN AMINOACIDAMINOTRANSFERASEILVE (Streptococcusmutans) |
PF01063(Aminotran_4) | 4 | ASN A 76ILE A 100GLU A 80ASN A 78 | None | 1.34A | 3kp6A-4dqnA:undetectable3kp6B-4dqnA:undetectable | 3kp6A-4dqnA:18.553kp6B-4dqnA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdd | RNA-BINDING PROTEINFUSTRANSPORTIN-1 (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ)no annotation | 4 | ASN A 807ILE A 804GLU A 809LYS B 507 | None | 1.20A | 3kp6A-4fddA:1.43kp6B-4fddA:undetectable | 3kp6A-4fddA:10.713kp6B-4fddA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl3 | PUTATIVEGLUCOAMYLASE (Bacteroidesuniformis) |
PF10091(Glycoamylase) | 4 | ASN A 131MET A 130ILE A 138GLU A 75 | None | 1.27A | 3kp6A-4gl3A:undetectable3kp6B-4gl3A:undetectable | 3kp6A-4gl3A:17.003kp6B-4gl3A:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkx | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | ASN E 150ILE E 65GLU E 72ASN E 68 | NoneNoneNoneNAG E 301 (-3.5A) | 1.35A | 3kp6A-4hkxE:undetectable3kp6B-4hkxE:undetectable | 3kp6A-4hkxE:21.153kp6B-4hkxE:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4u | TRANSCRIPTIONALREGULATOR (NTRCFAMILY) (Aquifexaeolicus) |
PF00072(Response_reg)PF00158(Sigma54_activat) | 4 | ASN A 355ILE A 307GLU A 168ASN A 280 | None | 1.24A | 3kp6A-4l4uA:undetectable3kp6B-4l4uA:undetectable | 3kp6A-4l4uA:19.063kp6B-4l4uA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb8 | URICASE (unclassifiedMammalia) |
PF01014(Uricase) | 4 | ILE A 276GLU A 280LYS A 278ASN A 267 | None | 1.44A | 3kp6A-4mb8A:undetectable3kp6B-4mb8A:undetectable | 3kp6A-4mb8A:19.873kp6B-4mb8A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mlo | TCP PILUS VIRULENCEREGULATORY PROTEIN (Vibrio cholerae) |
PF00165(HTH_AraC) | 4 | ILE A 104GLU A 156LYS A 157ASN A 160 | None | 1.07A | 3kp6A-4mloA:2.63kp6B-4mloA:2.6 | 3kp6A-4mloA:23.223kp6B-4mloA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n5c | CARGO-TRANSPORTPROTEIN YPP1 (Saccharomycescerevisiae) |
no annotation | 4 | ASN A 339MET A 313GLU A 335LYS A 333 | None | 1.23A | 3kp6A-4n5cA:undetectable3kp6B-4n5cA:undetectable | 3kp6A-4n5cA:10.473kp6B-4n5cA:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x3n | CALCIUM-REGULATEDACTIN-BUNDLINGPROTEIN (Dictyosteliumdiscoideum) |
no annotation | 4 | ILE A 276GLU A 179LYS A 271ASN A 51 | None | 1.46A | 3kp6A-4x3nA:1.33kp6B-4x3nA:0.5 | 3kp6A-4x3nA:20.393kp6B-4x3nA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE ACIDICPROTEIN (Influenza Cvirus) |
PF00603(Flu_PA) | 4 | MET A 387ILE A 390GLU A 385ASN A 383 | None | 1.12A | 3kp6A-5d9aA:1.83kp6B-5d9aA:2.5 | 3kp6A-5d9aA:13.933kp6B-5d9aA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE ACIDICPROTEINRNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Cvirus) |
PF00602(Flu_PB1)PF00603(Flu_PA) | 4 | ILE A 350GLU B 367LYS B 366ASN B 361 | None | 1.40A | 3kp6A-5d9aA:1.83kp6B-5d9aA:2.5 | 3kp6A-5d9aA:13.933kp6B-5d9aA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dpd | PROTEIN LYSINEMETHYLTRANSFERASE 1 (Rickettsiaprowazekii) |
PF10119(MethyTransf_Reg)PF13847(Methyltransf_31) | 4 | ASN A 114ILE A 87GLU A 110ASN A 112 | None | 1.33A | 3kp6A-5dpdA:undetectable3kp6B-5dpdA:undetectable | 3kp6A-5dpdA:15.493kp6B-5dpdA:15.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffj | ENDONUCLEASE ANDMETHYLASE LLAGI (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII) | 4 | ASN A 761ILE A 945GLU A 984ASN A 759 | None | 1.16A | 3kp6A-5ffjA:undetectable3kp6B-5ffjA:undetectable | 3kp6A-5ffjA:7.393kp6B-5ffjA:7.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2t | TREHALOSE SYNTHASE (Thermomonosporacurvata) |
no annotation | 4 | ASN A 357MET A 354ILE A 358ASN A 327 | None | 1.38A | 3kp6A-5h2tA:undetectable3kp6B-5h2tA:undetectable | 3kp6A-5h2tA:12.813kp6B-5h2tA:12.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjl | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Streptococcusporcinus) |
PF01791(DeoC) | 4 | MET A 190ILE A 163GLU A 188ASN A 187 | None | 1.47A | 3kp6A-5hjlA:undetectable3kp6B-5hjlA:0.3 | 3kp6A-5hjlA:20.433kp6B-5hjlA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huj | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Streptococcuspyogenes) |
PF02540(NAD_synthase) | 4 | ASN A 196ILE A 25GLU A 247LYS A 22 | None | 1.31A | 3kp6A-5hujA:undetectable3kp6B-5hujA:undetectable | 3kp6A-5hujA:20.073kp6B-5hujA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izt | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 4 | ILE A 323GLU A 201LYS A 199ASN A 200 | None | 1.48A | 3kp6A-5iztA:1.73kp6B-5iztA:1.5 | 3kp6A-5iztA:18.343kp6B-5iztA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m6w | STAPHYLOCOCCALCOMPLEMENT INHIBITOR (Staphylococcusaureus) |
PF11546(CompInhib_SCIN) | 4 | ASN N 29ILE N 44GLU N 25ASN N 27 | None | 1.24A | 3kp6A-5m6wN:1.83kp6B-5m6wN:2.1 | 3kp6A-5m6wN:21.853kp6B-5m6wN:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tky | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 4 | ASN A 454ILE A 414GLU A 456ASN A 458 | None | 1.38A | 3kp6A-5tkyA:0.33kp6B-5tkyA:undetectable | 3kp6A-5tkyA:14.293kp6B-5tkyA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v2m | MEVALONATEDIPHOSPHATEDECARBOXYLASE (Enterococcusfaecalis) |
no annotation | 4 | ILE A 15GLU A 213LYS A 214ASN A 211 | None | 1.43A | 3kp6A-5v2mA:undetectable3kp6B-5v2mA:undetectable | 3kp6A-5v2mA:17.773kp6B-5v2mA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp0 | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Aliivibriofischeri) |
PF02540(NAD_synthase) | 4 | ASN A 194ILE A 15GLU A 245LYS A 12 | None | 1.34A | 3kp6A-5wp0A:undetectable3kp6B-5wp0A:undetectable | 3kp6A-5wp0A:19.783kp6B-5wp0A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | ANTIBODY FAB HEAVYCHAIN (Mus musculus) |
no annotation | 4 | ASN A 35MET A 34ILE A 51ASN A 96 | None | 1.18A | 3kp6A-6c08A:undetectable3kp6B-6c08A:undetectable | 3kp6A-6c08A:19.743kp6B-6c08A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fah | CAFFEYL-COAREDUCTASE-ETFCOMPLEX SUBUNIT CARE (Acetobacteriumwoodii) |
no annotation | 4 | ASN A 365GLU A 364LYS A 362ASN A 361 | NoneNoneFAD A 401 (-4.7A)FAD A 401 (-2.9A) | 1.40A | 3kp6A-6fahA:undetectable3kp6B-6fahA:undetectable | 3kp6A-6fahA:16.883kp6B-6fahA:16.88 |