SIMILAR PATTERNS OF AMINO ACIDS FOR 3KP6_B_SALB3003
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1att | ANTITHROMBIN III (Bos taurus) |
PF00079(Serpin) | 4 | ILE A 413VAL A 411LEU A 284LEU A 273 | None | 0.78A | 3kp6A-1attA:0.03kp6B-1attA:0.0 | 3kp6A-1attA:16.083kp6B-1attA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dcn | DELTA 2 CRYSTALLIN (Anasplatyrhynchos) |
PF00206(Lyase_1)PF14698(ASL_C2) | 4 | ILE A 352VAL A 351LEU A 275LEU A 273 | None | 0.92A | 3kp6A-1dcnA:0.03kp6B-1dcnA:0.0 | 3kp6A-1dcnA:17.703kp6B-1dcnA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyt | CYTOSOLAMINOPEPTIDASE (Escherichiacoli) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | ILE A 18VAL A 20LEU A 75LEU A 62 | None | 0.89A | 3kp6A-1gytA:0.33kp6B-1gytA:0.0 | 3kp6A-1gytA:15.343kp6B-1gytA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h5y | HISF (Pyrobaculumaerophilum) |
PF00977(His_biosynth) | 4 | ILE A 237VAL A 240LEU A 244LEU A 5 | None | 0.78A | 3kp6A-1h5yA:undetectable3kp6B-1h5yA:undetectable | 3kp6A-1h5yA:21.573kp6B-1h5yA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htw | HI0065 (Haemophilusinfluenzae) |
PF02367(TsaE) | 4 | ILE A 127VAL A 129LEU A 38LEU A 111 | None | 0.81A | 3kp6A-1htwA:0.03kp6B-1htwA:undetectable | 3kp6A-1htwA:26.863kp6B-1htwA:26.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2m | REGULATOR OFCHROMOSOMECONDENSATION 1 (Homo sapiens) |
PF00415(RCC1) | 4 | VAL B 404LEU B 413HIS B 410LEU B 40 | None | 0.67A | 3kp6A-1i2mB:undetectable3kp6B-1i2mB:0.0 | 3kp6A-1i2mB:16.963kp6B-1i2mB:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iiw | SLR1257 PROTEIN (Synechocystissp. PCC 6803) |
PF00497(SBP_bac_3) | 4 | ILE A 183VAL A 185ARG A 163LEU A 166 | None | 0.83A | 3kp6A-1iiwA:undetectable3kp6B-1iiwA:undetectable | 3kp6A-1iiwA:20.803kp6B-1iiwA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j8m | SIGNAL RECOGNITION54 KDA PROTEIN (Acidianusambivalens) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | ILE F 73VAL F 76LEU F 80HIS F 294 | None | 0.80A | 3kp6A-1j8mF:0.03kp6B-1j8mF:0.1 | 3kp6A-1j8mF:19.873kp6B-1j8mF:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfg | D-HYDANTOINASE (Ralstoniapickettii) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | ILE A 382VAL A 49LEU A 392LEU A 428 | None | 0.72A | 3kp6A-1nfgA:0.03kp6B-1nfgA:undetectable | 3kp6A-1nfgA:17.943kp6B-1nfgA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsl | PROBABLEACETYLTRANSFERASE (Bacillussubtilis) |
PF13302(Acetyltransf_3) | 4 | ILE A 96VAL A 130HIS A 85LEU A 87 | None | 0.61A | 3kp6A-1nslA:undetectable3kp6B-1nslA:undetectable | 3kp6A-1nslA:25.763kp6B-1nslA:25.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ocm | MALONAMIDASE E2 (Bradyrhizobiumjaponicum) |
PF01425(Amidase) | 4 | ILE A 61VAL A 59LEU A 146LEU A 192 | None | 0.85A | 3kp6A-1ocmA:undetectable3kp6B-1ocmA:undetectable | 3kp6A-1ocmA:15.003kp6B-1ocmA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ovm | INDOLE-3-PYRUVATEDECARBOXYLASE (Enterobactercloacae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ILE A 526VAL A 528LEU A 460LEU A 432 | None | 0.67A | 3kp6A-1ovmA:0.03kp6B-1ovmA:undetectable | 3kp6A-1ovmA:14.753kp6B-1ovmA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi9 | PROTEIN (VANADIUMBROMOPEROXIDASE) (Ascophyllumnodosum) |
no annotation | 4 | ILE A 386VAL A 383ARG A 382LEU A 379 | None | 0.64A | 3kp6A-1qi9A:0.53kp6B-1qi9A:0.3 | 3kp6A-1qi9A:15.233kp6B-1qi9A:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qw1 | DIPHTHERIA TOXINREPRESSOR (Corynebacteriumdiphtheriae) |
no annotation | 4 | ILE A 223VAL A 152ARG A 151LEU A 138 | None | 0.93A | 3kp6A-1qw1A:undetectable3kp6B-1qw1A:undetectable | 3kp6A-1qw1A:24.523kp6B-1qw1A:24.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r47 | ALPHA-GALACTOSIDASEA (Homo sapiens) |
PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | ILE A 407VAL A 413LEU A 415LEU A 403 | None | 0.89A | 3kp6A-1r47A:undetectable3kp6B-1r47A:undetectable | 3kp6A-1r47A:17.513kp6B-1r47A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x5r | GLUTAMATE RECEPTORINTERACTING PROTEIN2 (Homo sapiens) |
PF00595(PDZ) | 4 | ILE A 52VAL A 49LEU A 33LEU A 90 | None | 0.84A | 3kp6A-1x5rA:undetectable3kp6B-1x5rA:undetectable | 3kp6A-1x5rA:23.753kp6B-1x5rA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yjk | PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE (Rattusnorvegicus) |
PF01082(Cu2_monooxygen)PF03712(Cu2_monoox_C) | 4 | ILE A 66VAL A 191LEU A 193LEU A 86 | None | 0.73A | 3kp6A-1yjkA:undetectable3kp6B-1yjkA:undetectable | 3kp6A-1yjkA:20.223kp6B-1yjkA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | ILE I 412VAL I 410LEU I 283LEU I 272 | None | 0.89A | 3kp6A-2b4xI:0.43kp6B-2b4xI:undetectable | 3kp6A-2b4xI:20.573kp6B-2b4xI:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bex | RIBONUCLEASEINHIBITOR (Homo sapiens) |
PF13516(LRR_6) | 4 | ILE A 181VAL A 176LEU A 148LEU A 129 | None | 0.87A | 3kp6A-2bexA:undetectable3kp6B-2bexA:undetectable | 3kp6A-2bexA:15.323kp6B-2bexA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4n | PROTEIN NAGD (Escherichiacoli) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | ILE A 250VAL A 6LEU A 38LEU A 28 | None | 0.92A | 3kp6A-2c4nA:undetectable3kp6B-2c4nA:undetectable | 3kp6A-2c4nA:21.863kp6B-2c4nA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cy4 | EPIDERMAL GROWTHFACTOR RECEPTORPATHWAY SUBSTRATE8-LIKE PROTEIN 1 (Mus musculus) |
PF08416(PTB) | 4 | VAL A 85LEU A 78HIS A 135LEU A 120 | None | 0.88A | 3kp6A-2cy4A:undetectable3kp6B-2cy4A:undetectable | 3kp6A-2cy4A:22.993kp6B-2cy4A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyq | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Escherichiacoli) |
PF00270(DEAD)PF00271(Helicase_C)PF02559(CarD_CdnL_TRCF)PF03461(TRCF) | 4 | ILE A 45VAL A 43LEU A 106LEU A 70 | None | 0.86A | 3kp6A-2eyqA:undetectable3kp6B-2eyqA:undetectable | 3kp6A-2eyqA:9.373kp6B-2eyqA:9.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fm8 | CELL INVASIONPROTEIN SIPA (Salmonellaenterica) |
PF09052(SipA) | 4 | ILE C 187VAL C 183LEU C 155LEU C 152 | None | 0.93A | 3kp6A-2fm8C:undetectable3kp6B-2fm8C:undetectable | 3kp6A-2fm8C:23.503kp6B-2fm8C:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fvz | INOSITOLMONOPHOSPHATASE 2 (Homo sapiens) |
PF00459(Inositol_P) | 4 | ILE A 120VAL A 132LEU A 141LEU A 28 | None | 0.81A | 3kp6A-2fvzA:undetectable3kp6B-2fvzA:undetectable | 3kp6A-2fvzA:22.113kp6B-2fvzA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmu | PUTATIVEPYRIDOXAMINE5-PHOSPHATE-DEPENDENT DEHYDRASE, WBDK (Escherichiacoli) |
PF01041(DegT_DnrJ_EryC1) | 4 | ILE A 328VAL A 369LEU A 367LEU A 319 | None | 0.87A | 3kp6A-2gmuA:undetectable3kp6B-2gmuA:undetectable | 3kp6A-2gmuA:18.183kp6B-2gmuA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hm2 | PYRIN-ONLY PROTEIN 1 (Homo sapiens) |
PF02758(PYRIN) | 4 | VAL Q 72ARG Q 74LEU Q 73LEU Q 85 | None | 0.76A | 3kp6A-2hm2Q:undetectable3kp6B-2hm2Q:undetectable | 3kp6A-2hm2Q:21.853kp6B-2hm2Q:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ho4 | HALOACIDDEHALOGENASE-LIKEHYDROLASE DOMAINCONTAINING 2 (Mus musculus) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | ILE A 221VAL A 200LEU A 7HIS A 253 | None | 0.88A | 3kp6A-2ho4A:undetectable3kp6B-2ho4A:undetectable | 3kp6A-2ho4A:20.003kp6B-2ho4A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpa | PROTEIN (ACIDPHOSPHATASE) (Homo sapiens) |
PF00328(His_Phos_2) | 4 | ILE A1332VAL A1328LEU A1268LEU A1264 | None | 0.87A | 3kp6A-2hpaA:0.53kp6B-2hpaA:undetectable | 3kp6A-2hpaA:15.273kp6B-2hpaA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jcs | DEOXYNUCLEOSIDEKINASE (Drosophilamelanogaster) |
PF01712(dNK) | 4 | ILE A 25VAL A 23LEU A 149LEU A 203 | None | 0.91A | 3kp6A-2jcsA:undetectable3kp6B-2jcsA:undetectable | 3kp6A-2jcsA:23.483kp6B-2jcsA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3f | PUTATIVE HTH-TYPETRANSCRIPTIONALREGULATOR YBBH (Bacillussubtilis) |
PF01418(HTH_6) | 4 | VAL A 72ARG A 71LEU A 68LEU A 60 | MLY A 69 ( 4.0A)NoneMLY A 69 ( 3.6A)None | 0.80A | 3kp6A-2o3fA:1.43kp6B-2o3fA:1.8 | 3kp6A-2o3fA:23.653kp6B-2o3fA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ool | SENSOR PROTEIN (Rhodopseudomonaspalustris) |
PF01590(GAF)PF08446(PAS_2) | 4 | ILE A 128VAL A 47LEU A 45LEU A 257 | None | 0.89A | 3kp6A-2oolA:undetectable3kp6B-2oolA:undetectable | 3kp6A-2oolA:17.723kp6B-2oolA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q78 | UNCHARACTERIZEDPROTEIN (Thermotogamaritima) |
no annotation | 4 | ILE A 118VAL A 96ARG A 116LEU A 52 | NoneNoneMLC A 200 ( 4.1A)None | 0.79A | 3kp6A-2q78A:undetectable3kp6B-2q78A:undetectable | 3kp6A-2q78A:24.263kp6B-2q78A:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsx | PUTATIVETRANSCRIPTIONALREGULATOR, LYSRFAMILY (Vibrioparahaemolyticus) |
PF03466(LysR_substrate) | 4 | ILE A 49VAL A 47LEU A 18LEU A 65 | None | 0.83A | 3kp6A-2qsxA:undetectable3kp6B-2qsxA:undetectable | 3kp6A-2qsxA:18.263kp6B-2qsxA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2riu | 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATESYNTHASE (Candidaalbicans) |
PF00926(DHBP_synthase) | 4 | ILE A 129VAL A 60LEU A 62LEU A 70 | None | 0.72A | 3kp6A-2riuA:undetectable3kp6B-2riuA:undetectable | 3kp6A-2riuA:19.423kp6B-2riuA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zvw | PROLIFERATING CELLNUCLEAR ANTIGEN 2 (Arabidopsisthaliana) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | ILE A 247VAL A 19LEU A 16LEU A 12 | None | 0.92A | 3kp6A-2zvwA:undetectable3kp6B-2zvwA:undetectable | 3kp6A-2zvwA:19.713kp6B-2zvwA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3akk | CTKA (Helicobacterpylori) |
PF07804(HipA_C) | 4 | ILE A 283ARG A 278LEU A 275LEU A 151 | None | 0.79A | 3kp6A-3akkA:undetectable3kp6B-3akkA:undetectable | 3kp6A-3akkA:20.733kp6B-3akkA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bh1 | UPF0371 PROTEINDIP2346 (Corynebacteriumdiphtheriae) |
PF08903(DUF1846) | 4 | ILE A 70VAL A 68LEU A 173LEU A 33 | None | 0.70A | 3kp6A-3bh1A:undetectable3kp6B-3bh1A:undetectable | 3kp6A-3bh1A:17.173kp6B-3bh1A:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dpu | RAB FAMILY PROTEIN (Chlorobaculumtepidum) |
PF08477(Roc)PF16095(COR) | 4 | ILE A 565VAL A 567LEU A 539LEU A 457 | None | 0.66A | 3kp6A-3dpuA:undetectable3kp6B-3dpuA:4.8 | 3kp6A-3dpuA:16.213kp6B-3dpuA:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f2b | DNA-DIRECTED DNAPOLYMERASE III ALPHACHAIN (Geobacilluskaustophilus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 4 | ILE A 319VAL A 304LEU A 324LEU A 267 | None | 0.92A | 3kp6A-3f2bA:undetectable3kp6B-3f2bA:undetectable | 3kp6A-3f2bA:10.623kp6B-3f2bA:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw6 | CELLULASE (unculturedbacterium) |
PF12891(Glyco_hydro_44) | 4 | ILE A 37VAL A 39LEU A 499LEU A 532 | None | 0.82A | 3kp6A-3fw6A:undetectable3kp6B-3fw6A:undetectable | 3kp6A-3fw6A:14.153kp6B-3fw6A:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gqm | CELL INHIBITINGFACTOR (CIFBP) (Burkholderiapseudomallei) |
PF16374(CIF) | 4 | ILE A 230VAL A 228LEU A 173LEU A 143 | None | 0.85A | 3kp6A-3gqmA:undetectable3kp6B-3gqmA:undetectable | 3kp6A-3gqmA:19.223kp6B-3gqmA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdv | RESPONSE REGULATOR (Pseudomonasputida) |
PF00072(Response_reg) | 4 | ILE A 146VAL A 182LEU A 179LEU A 175 | None | 0.91A | 3kp6A-3hdvA:undetectable3kp6B-3hdvA:undetectable | 3kp6A-3hdvA:21.743kp6B-3hdvA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hm7 | ALLANTOINASE (Bacillushalodurans) |
PF01979(Amidohydro_1) | 4 | ILE A 217VAL A 248LEU A 249LEU A 300 | None | 0.83A | 3kp6A-3hm7A:undetectable3kp6B-3hm7A:undetectable | 3kp6A-3hm7A:17.393kp6B-3hm7A:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i99 | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Vibrio cholerae) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | ILE A 84VAL A 97LEU A 192LEU A 118 | None | 0.85A | 3kp6A-3i99A:undetectable3kp6B-3i99A:undetectable | 3kp6A-3i99A:16.623kp6B-3i99A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivr | PUTATIVELONG-CHAIN-FATTY-ACID COA LIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding) | 4 | ILE A 80VAL A 77LEU A 73LEU A 147 | None | 0.91A | 3kp6A-3ivrA:undetectable3kp6B-3ivrA:undetectable | 3kp6A-3ivrA:14.573kp6B-3ivrA:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krs | TRIOSEPHOSPHATEISOMERASE (Cryptosporidiumparvum) |
PF00121(TIM) | 4 | ILE A 209ARG A 207LEU A 206LEU A 162 | None | 0.90A | 3kp6A-3krsA:undetectable3kp6B-3krsA:undetectable | 3kp6A-3krsA:19.713kp6B-3krsA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kyd | SUMO-ACTIVATINGENZYME SUBUNIT 1 (Homo sapiens) |
PF00899(ThiF) | 4 | ILE A 272VAL A 276LEU A 277LEU A 287 | None | 0.86A | 3kp6A-3kydA:undetectable3kp6B-3kydA:undetectable | 3kp6A-3kydA:19.833kp6B-3kydA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mml | ALLOPHANATEHYDROLASE SUBUNIT 1 (Mycolicibacteriumsmegmatis) |
PF02682(CT_C_D) | 4 | ILE B 42VAL B 39LEU B 53LEU B 14 | None | 0.76A | 3kp6A-3mmlB:undetectable3kp6B-3mmlB:undetectable | 3kp6A-3mmlB:20.873kp6B-3mmlB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phf | ENVELOPEGLYCOPROTEIN H (Humangammaherpesvirus4) |
no annotation | 4 | ILE A 599VAL A 667LEU A 661LEU A 620 | None | 0.93A | 3kp6A-3phfA:undetectable3kp6B-3phfA:undetectable | 3kp6A-3phfA:12.343kp6B-3phfA:12.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pmk | NUCLEOCAPSID PROTEIN (RecombinantvesicularstomatitisIndiana virusrVSV-G/GFP) |
PF00945(Rhabdo_ncap) | 4 | ILE A 66VAL A 69LEU A 138LEU A 141 | None | 0.92A | 3kp6A-3pmkA:undetectable3kp6B-3pmkA:undetectable | 3kp6A-3pmkA:18.643kp6B-3pmkA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qjp | PUTATIVEUNCHARACTERIZEDPROTEIN PH0350 (Pyrococcushorikoshii) |
PF01881(Cas_Cas6) | 4 | ILE A 112VAL A 109LEU A 7LEU A 77 | None | 0.72A | 3kp6A-3qjpA:undetectable3kp6B-3qjpA:undetectable | 3kp6A-3qjpA:22.733kp6B-3qjpA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qy3 | THIOESTERASE (Pseudomonasaeruginosa) |
PF13279(4HBT_2) | 4 | VAL A 58LEU A 112HIS A 109LEU A 91 | None | 0.73A | 3kp6A-3qy3A:undetectable3kp6B-3qy3A:undetectable | 3kp6A-3qy3A:18.013kp6B-3qy3A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6k | RESPONSE REGULATORRECEIVER (Chloroflexusaurantiacus) |
PF00072(Response_reg) | 4 | ILE A 120VAL A 117ARG A 116LEU A 113 | None | 0.83A | 3kp6A-3t6kA:undetectable3kp6B-3t6kA:undetectable | 3kp6A-3t6kA:22.933kp6B-3t6kA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7c | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | ILE A 34VAL A 63ARG A 68LEU A 66 | None | 0.82A | 3kp6A-3t7cA:undetectable3kp6B-3t7cA:undetectable | 3kp6A-3t7cA:20.333kp6B-3t7cA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tev | GLYCOSYL HYROLASE,FAMILY 3 (Deinococcusradiodurans) |
PF00933(Glyco_hydro_3) | 4 | ILE A 74VAL A 44LEU A 23LEU A 28 | None | 0.85A | 3kp6A-3tevA:undetectable3kp6B-3tevA:0.7 | 3kp6A-3tevA:17.563kp6B-3tevA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ua4 | PROTEIN ARGININEN-METHYLTRANSFERASE5 (Caenorhabditiselegans) |
PF05185(PRMT5)PF17285(PRMT5_TIM)PF17286(PRMT5_C) | 4 | ILE A 473VAL A 471LEU A 446LEU A 412 | None | 0.84A | 3kp6A-3ua4A:undetectable3kp6B-3ua4A:undetectable | 3kp6A-3ua4A:13.013kp6B-3ua4A:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vjz | PUTATIVEUNCHARACTERIZEDPROTEIN (Neisseriameningitidis) |
PF14300(DUF4375) | 4 | ILE A 89VAL A 92LEU A 96LEU A 80 | None | 0.79A | 3kp6A-3vjzA:undetectable3kp6B-3vjzA:undetectable | 3kp6A-3vjzA:24.263kp6B-3vjzA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7k | ALDOS-2-ULOSEDEHYDRATASE (Phanerochaetechrysosporium) |
no annotation | 4 | ILE A 219VAL A 217LEU A 236LEU A 245 | None | 0.79A | 3kp6A-4a7kA:undetectable3kp6B-4a7kA:undetectable | 3kp6A-4a7kA:11.103kp6B-4a7kA:11.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4am6 | ACTIN-LIKE PROTEINARP8 (Saccharomycescerevisiae) |
PF00022(Actin) | 4 | ILE A 422VAL A 425LEU A 429LEU A 470 | None | 0.51A | 3kp6A-4am6A:3.03kp6B-4am6A:undetectable | 3kp6A-4am6A:13.003kp6B-4am6A:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9c | TYPE 3ACELLULOSE-BINDINGDOMAIN PROTEIN (Ruminiclostridiumthermocellum) |
PF00942(CBM_3) | 4 | ILE A 140VAL A 40LEU A 37LEU A 96 | None | 0.87A | 3kp6A-4b9cA:undetectable3kp6B-4b9cA:undetectable | 3kp6A-4b9cA:22.983kp6B-4b9cA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bju | N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE (Aspergillusfumigatus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I) | 4 | ILE A 107VAL A 110LEU A 114LEU A 49 | None | 0.72A | 3kp6A-4bjuA:undetectable3kp6B-4bjuA:undetectable | 3kp6A-4bjuA:16.243kp6B-4bjuA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3h | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA190 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | ILE A 438VAL A 456LEU A 460LEU A1622 | None | 0.62A | 3kp6A-4c3hA:undetectable3kp6B-4c3hA:undetectable | 3kp6A-4c3hA:6.933kp6B-4c3hA:6.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecm | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Bacillusanthracis) |
PF00483(NTP_transferase) | 4 | ILE A 105VAL A 103LEU A 173LEU A 132 | None | 0.81A | 3kp6A-4ecmA:undetectable3kp6B-4ecmA:undetectable | 3kp6A-4ecmA:21.883kp6B-4ecmA:21.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4eju | TRANSCRIPTIONALREGULATOR TCAR (Staphylococcusepidermidis) |
PF12802(MarR_2) | 4 | ILE A 130VAL A 133ARG A 134LEU A 137 | None | 0.51A | 3kp6A-4ejuA:18.73kp6B-4ejuA:19.6 | 3kp6A-4ejuA:100.003kp6B-4ejuA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 4 | ILE A 189VAL A 167LEU A 147LEU A 173 | None | 0.81A | 3kp6A-4fdwA:undetectable3kp6B-4fdwA:undetectable | 3kp6A-4fdwA:18.413kp6B-4fdwA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gct | NUCLEOID OCCLUSIONFACTOR SLMA (Vibrio cholerae) |
PF00440(TetR_N) | 4 | ILE A 86VAL A 89LEU A 93LEU A 161 | None | 0.72A | 3kp6A-4gctA:undetectable3kp6B-4gctA:1.4 | 3kp6A-4gctA:21.133kp6B-4gctA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hlu | ENERGY-COUPLINGFACTOR TRANSPORTERATP-BINDING PROTEINECFA (Thermotogamaritima) |
no annotation | 4 | ILE D1170VAL D1173LEU D1177LEU D1153 | None | 0.75A | 3kp6A-4hluD:undetectable3kp6B-4hluD:undetectable | 3kp6A-4hluD:22.183kp6B-4hluD:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imv | RICIN (Ricinuscommunis) |
PF00161(RIP) | 4 | ILE A 25VAL A 28ARG A 29LEU A 32 | None | 0.93A | 3kp6A-4imvA:undetectable3kp6B-4imvA:undetectable | 3kp6A-4imvA:20.213kp6B-4imvA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jw1 | EFFECTOR PROTEIN B (Legionellapneumophila) |
no annotation | 4 | ILE A 304ARG A 300LEU A 297LEU A 148 | None | 0.84A | 3kp6A-4jw1A:1.33kp6B-4jw1A:undetectable | 3kp6A-4jw1A:15.093kp6B-4jw1A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc5 | RHIE PROTEIN (Paraburkholderiarhizoxinica) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ILE A3898VAL A3895LEU A3947LEU A3927 | None | 0.69A | 3kp6A-4kc5A:undetectable3kp6B-4kc5A:undetectable | 3kp6A-4kc5A:10.433kp6B-4kc5A:10.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kyi | VIPD (Legionellapneumophila) |
PF01734(Patatin) | 4 | ILE A 233LEU A 224HIS A 133LEU A 134 | None | 0.93A | 3kp6A-4kyiA:undetectable3kp6B-4kyiA:undetectable | 3kp6A-4kyiA:14.923kp6B-4kyiA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lkb | HYPOTHETICAL PROTEINALR4568/PUTATIVE4-OXALOCROTONATETAUTOMERASE (Nostoc sp. PCC7120) |
no annotation | 4 | ILE F 34VAL F 2HIS F 25LEU F 24 | None | 0.79A | 3kp6A-4lkbF:undetectable3kp6B-4lkbF:undetectable | 3kp6A-4lkbF:24.563kp6B-4lkbF:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lnz | UNCONVENTIONALMYOSIN-VB (Homo sapiens) |
PF01843(DIL) | 4 | ILE A1678VAL A1681LEU A1685HIS A1665 | None | 0.80A | 3kp6A-4lnzA:undetectable3kp6B-4lnzA:undetectable | 3kp6A-4lnzA:17.103kp6B-4lnzA:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4los | COMPLEMENT C1SSUBCOMPONENT HEAVYCHAIN (Homo sapiens) |
PF00084(Sushi)PF00431(CUB) | 4 | ILE A 246VAL A 201LEU A 270LEU A 223 | None | 0.88A | 3kp6A-4losA:undetectable3kp6B-4losA:undetectable | 3kp6A-4losA:21.883kp6B-4losA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lr2 | BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 (Homo sapiens) |
PF01663(Phosphodiest) | 4 | ILE A 365VAL A 62HIS A 362LEU A 58 | None | 0.82A | 3kp6A-4lr2A:undetectable3kp6B-4lr2A:undetectable | 3kp6A-4lr2A:19.383kp6B-4lr2A:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nes | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Methanocaldococcusjannaschii) |
PF02350(Epimerase_2) | 4 | ILE A 321VAL A 323LEU A 305LEU A 285 | None | 0.87A | 3kp6A-4nesA:undetectable3kp6B-4nesA:undetectable | 3kp6A-4nesA:19.843kp6B-4nesA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7w | L-PROLINECIS-4-HYDROXYLASE (Mesorhizobiumjaponicum) |
PF05118(Asp_Arg_Hydrox)PF05373(Pro_3_hydrox_C) | 4 | ILE A 145VAL A 9LEU A 11LEU A 123 | None | 0.90A | 3kp6A-4p7wA:undetectable3kp6B-4p7wA:undetectable | 3kp6A-4p7wA:23.273kp6B-4p7wA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pbc | D-AMINO ACIDAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01063(Aminotran_4) | 4 | VAL A 114LEU A 116HIS A 70LEU A 71 | NoneNonePO4 A 401 ( 4.9A)None | 0.83A | 3kp6A-4pbcA:undetectable3kp6B-4pbcA:undetectable | 3kp6A-4pbcA:19.123kp6B-4pbcA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4peq | RIBONUCLEASE/ANGIOGENIN INHIBITOR 1 (Bos taurus) |
PF13516(LRR_6) | 4 | ILE B 177VAL B 172LEU B 144LEU B 125 | None | 0.92A | 3kp6A-4peqB:undetectable3kp6B-4peqB:undetectable | 3kp6A-4peqB:14.163kp6B-4peqB:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r70 | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB2 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | ILE A 128VAL A 47LEU A 45LEU A 257 | None | 0.79A | 3kp6A-4r70A:undetectable3kp6B-4r70A:undetectable | 3kp6A-4r70A:14.633kp6B-4r70A:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9o | PUTATIVE ALDO/KETOREDUCTASE (Salmonellaenterica) |
PF00248(Aldo_ket_red) | 4 | ILE A 266VAL A 269ARG A 270LEU A 273 | None | 0.85A | 3kp6A-4r9oA:undetectable3kp6B-4r9oA:2.7 | 3kp6A-4r9oA:21.163kp6B-4r9oA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rx1 | PUTATIVE RRNAMETHYLTRANSFERASE (Sorangiumcellulosum) |
no annotation | 4 | ILE A 29VAL A 31LEU A 103LEU A 135 | None | 0.76A | 3kp6A-4rx1A:undetectable3kp6B-4rx1A:undetectable | 3kp6A-4rx1A:20.513kp6B-4rx1A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tmz | EIF5B (Chaetomiumthermophilum) |
no annotation | 4 | ILE B 780VAL B 841LEU B 748LEU B 769 | None | 0.90A | 3kp6A-4tmzB:undetectable3kp6B-4tmzB:undetectable | 3kp6A-4tmzB:20.253kp6B-4tmzB:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1y | ATRAZINECHLOROHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 4 | ILE A 384VAL A 58LEU A 394LEU A 425 | None | 0.92A | 3kp6A-4v1yA:0.73kp6B-4v1yA:0.4 | 3kp6A-4v1yA:13.743kp6B-4v1yA:13.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w9r | UNCHARACTERIZEDPROTEIN (Capnocytophagaochracea) |
PF00756(Esterase) | 4 | ILE A 160VAL A 135LEU A 57LEU A 144 | None | 0.65A | 3kp6A-4w9rA:undetectable3kp6B-4w9rA:undetectable | 3kp6A-4w9rA:18.973kp6B-4w9rA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z64 | PHYTOSULFOKINERECEPTOR 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 4 | ILE A 174VAL A 177LEU A 201LEU A 219 | None | 0.93A | 3kp6A-4z64A:undetectable3kp6B-4z64A:undetectable | 3kp6A-4z64A:12.363kp6B-4z64A:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah4 | DNA POLYMERASE IIISUBUNIT BETA (Mycolicibacteriumsmegmatis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | ILE A 169VAL A 167LEU A 176LEU A 189 | None | 0.71A | 3kp6A-5ah4A:undetectable3kp6B-5ah4A:undetectable | 3kp6A-5ah4A:17.713kp6B-5ah4A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dds | CRMG (Actinoalloteichussp. WH1-2216-6) |
PF00202(Aminotran_3) | 4 | ILE A 335VAL A 293LEU A 297HIS A 302 | None | 0.90A | 3kp6A-5ddsA:1.33kp6B-5ddsA:0.6 | 3kp6A-5ddsA:14.533kp6B-5ddsA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey5 | LBCA-B (syntheticconstruct) |
PF00291(PALP) | 4 | ILE B 368VAL B 370LEU B 72LEU B 61 | None | 0.90A | 3kp6A-5ey5B:undetectable3kp6B-5ey5B:undetectable | 3kp6A-5ey5B:18.013kp6B-5ey5B:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ftp | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 8 (Schizosaccharomycespombe) |
PF04049(ANAPC8) | 4 | ILE A 158VAL A 161LEU A 165LEU A 175 | None | 0.78A | 3kp6A-5ftpA:undetectable3kp6B-5ftpA:undetectable | 3kp6A-5ftpA:19.573kp6B-5ftpA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gv0 | LYSOSOME-ASSOCIATEDMEMBRANEGLYCOPROTEIN 1 (Mus musculus) |
PF01299(Lamp) | 4 | ILE A 333VAL A 335LEU A 339LEU A 231 | None | 0.82A | 3kp6A-5gv0A:undetectable3kp6B-5gv0A:undetectable | 3kp6A-5gv0A:22.163kp6B-5gv0A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hw3 | BETA-LACTAMASE (Burkholderiavietnamiensis) |
PF13354(Beta-lactamase2) | 4 | VAL A 197ARG A 203LEU A 198LEU A 206 | None | 0.92A | 3kp6A-5hw3A:undetectable3kp6B-5hw3A:1.8 | 3kp6A-5hw3A:19.053kp6B-5hw3A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jcn | OS09G0567300 PROTEIN (Oryza sativa) |
PF07992(Pyr_redox_2) | 4 | ILE A 255VAL A 257LEU A 179LEU A 56 | None | 0.80A | 3kp6A-5jcnA:undetectable3kp6B-5jcnA:undetectable | 3kp6A-5jcnA:16.093kp6B-5jcnA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcx | (-)-ISOPIPERITENONEREDUCTASE (Mentha xpiperita) |
PF00106(adh_short) | 4 | ILE A 30VAL A 32LEU A 60LEU A 53 | None | 0.86A | 3kp6A-5lcxA:undetectable3kp6B-5lcxA:undetectable | 3kp6A-5lcxA:23.213kp6B-5lcxA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mac | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE-OXYGENASE TYPE III (Methanococcoidesburtonii) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | ILE A 92VAL A 90LEU A 83LEU A 22 | NoneNoneNone CL A 504 (-3.9A) | 0.87A | 3kp6A-5macA:undetectable3kp6B-5macA:undetectable | 3kp6A-5macA:14.483kp6B-5macA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t81 | EPOB (Sorangiumcellulosum) |
PF00668(Condensation) | 4 | ILE A 145VAL A 184LEU A 198LEU A 430 | None | 0.84A | 3kp6A-5t81A:undetectable3kp6B-5t81A:undetectable | 3kp6A-5t81A:15.823kp6B-5t81A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u89 | AMINO ACIDADENYLATION DOMAINPROTEIN (Geobacillus sp.Y4.1MC1) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF13193(AMP-binding_C) | 4 | ILE A1492VAL A1481LEU A1478LEU A1474 | None | 0.88A | 3kp6A-5u89A:undetectable3kp6B-5u89A:undetectable | 3kp6A-5u89A:9.643kp6B-5u89A:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ufq | R11.1.6 (Sulfolobussolfataricus) |
no annotation | 4 | ILE C 19VAL C 22LEU C 58LEU C 55 | None | 0.89A | 3kp6A-5ufqC:undetectable3kp6B-5ufqC:undetectable | 3kp6A-5ufqC:13.823kp6B-5ufqC:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wm0 | PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE (Rattusnorvegicus) |
no annotation | 4 | ILE A 66VAL A 191LEU A 193LEU A 86 | None | 0.71A | 3kp6A-5wm0A:undetectable3kp6B-5wm0A:undetectable | 3kp6A-5wm0A:undetectable3kp6B-5wm0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d47 | BETA SLIDING CLAMP (Mycobacteriummarinum) |
no annotation | 4 | ILE A 171VAL A 169LEU A 178LEU A 191 | None | 0.79A | 3kp6A-6d47A:undetectable3kp6B-6d47A:undetectable | 3kp6A-6d47A:21.743kp6B-6d47A:21.74 |