SIMILAR PATTERNS OF AMINO ACIDS FOR 3KP3_B_AICB2002

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d02 TYPE II RESTRICTION
ENZYME MUNI

(Mycoplasma) 		PF11407
(RestrictionMunI) 		3 ALA A 118
ARG A 121
LYS A 124
 None
 0.90A 3kp3B-1d02A:
undetectable		 3kp3B-1d02A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fxj UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Escherichia
coli) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		3 ALA A 178
ARG A 182
LYS A 186
 ALA  A 178 ( 0.0A)
ARG  A 182 ( 0.6A)
LYS  A 186 ( 0.0A)
 1.03A 3kp3B-1fxjA:
0.1		 3kp3B-1fxjA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1n GENOME POLYPROTEIN:
PICORNAIN 3C

(Enterovirus C) 		PF00548
(Peptidase_C3) 		3 ALA A 133
ARG A 134
LYS A 175
 None
 0.89A 3kp3B-1l1nA:
undetectable		 3kp3B-1l1nA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lw3 MYOTUBULARIN-RELATED
PROTEIN 2

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		3 ALA A 472
ARG A 476
LYS A 156
 None
 0.96A 3kp3B-1lw3A:
0.0		 3kp3B-1lw3A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		3 ALA A 406
ARG A 410
LYS A 414
 None
 0.60A 3kp3B-1tf0A:
0.7		 3kp3B-1tf0A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u8v GAMMA-AMINOBUTYRATE
METABOLISM
DEHYDRATASE/ISOMERAS
E

(Clostridium
aminobutyricum) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 ALA A 349
ARG A  83
LYS A  87
 None
 0.90A 3kp3B-1u8vA:
0.0		 3kp3B-1u8vA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaz ARCHAERHODOPSIN-1

(Halorubrum
chaoviator) 		PF01036
(Bac_rhodopsin) 		3 ALA A 159
ARG A 163
LYS A 167
 None
 0.86A 3kp3B-1uazA:
0.0		 3kp3B-1uazA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v72 ALDOLASE

(Pseudomonas
putida) 		PF01212
(Beta_elim_lyase) 		3 ALA A 294
ARG A 182
LYS A 212
 None
PLP  A 513 (-3.3A)
PLP  A 513 (-1.3A)
 0.98A 3kp3B-1v72A:
0.0		 3kp3B-1v72A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9l GLUTAMATE
DEHYDROGENASE

(Pyrobaculum
islandicum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ALA A 194
ARG A 198
LYS A 202
 None
 0.62A 3kp3B-1v9lA:
0.0		 3kp3B-1v9lA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zsq MYOTUBULARIN-RELATED
PROTEIN 2

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		3 ALA A 472
ARG A 476
LYS A 156
 EDO  A1879 (-4.4A)
None
None
 1.02A 3kp3B-1zsqA:
0.0		 3kp3B-1zsqA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8i THREONINE ASPARTASE
1

(Homo sapiens) 		PF01112
(Asparaginase_2) 		3 ALA A 194
ARG A 198
LYS A 202
 None
 0.82A 3kp3B-2a8iA:
undetectable		 3kp3B-2a8iA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bd0 SEPIAPTERIN
REDUCTASE

(Chlorobaculum
tepidum) 		PF00106
(adh_short) 		3 ALA A  17
ARG A  16
LYS A  48
 None
 0.97A 3kp3B-2bd0A:
undetectable		 3kp3B-2bd0A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4k PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE-ASSOCIATE
D PROTEIN 1

(Homo sapiens) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		3 ALA A 153
ARG A 152
LYS A 138
 None
 1.06A 3kp3B-2c4kA:
undetectable		 3kp3B-2c4kA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00478
(IMPDH)
PF00571
(CBS) 		3 ALA A  66
ARG A  69
LYS A 207
 None
 0.87A 3kp3B-2cu0A:
undetectable		 3kp3B-2cu0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi1 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE 2

(Salmonella
enterica) 		PF04166
(PdxA) 		3 ALA A  42
ARG A  46
LYS A  50
 None
 0.67A 3kp3B-2hi1A:
undetectable		 3kp3B-2hi1A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsi PUTATIVE PEPTIDASE
M23

(Pseudomonas
aeruginosa) 		PF01551
(Peptidase_M23) 		3 ALA A 139
ARG A 142
LYS A  58
 None
 1.00A 3kp3B-2hsiA:
undetectable		 3kp3B-2hsiA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2if4 ATFKBP42

(Arabidopsis
thaliana) 		PF00254
(FKBP_C)
PF13181
(TPR_8) 		3 ALA A 266
ARG A 270
LYS A 274
 None
 1.04A 3kp3B-2if4A:
undetectable		 3kp3B-2if4A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE

(Enterovirus C) 		PF00548
(Peptidase_C3)
PF00680
(RdRP_1) 		3 ALA 1 133
ARG 1 134
LYS 1 175
 None
SO4  1 646 (-2.6A)
SO4  1 646 ( 3.7A)
 0.91A 3kp3B-2ijd1:
undetectable		 3kp3B-2ijd1:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ljp RIBONUCLEASE P
PROTEIN COMPONENT

(Escherichia
coli) 		PF00825
(Ribonuclease_P) 		3 ALA A  59
ARG A  62
LYS A  66
 None
 0.57A 3kp3B-2ljpA:
undetectable		 3kp3B-2ljpA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mnw PROTEIN SHQ1 HOMOLOG

(Homo sapiens) 		no annotation 3 ALA A  93
ARG A  48
LYS A  39
 None
 0.96A 3kp3B-2mnwA:
undetectable		 3kp3B-2mnwA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2myi EXODEOXYRIBONUCLEASE
III

(Pseudomonas sp.
Lz4W) 		PF03372
(Exo_endo_phos) 		3 ALA A 176
ARG A 175
LYS A 155
 None
 0.94A 3kp3B-2myiA:
undetectable		 3kp3B-2myiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nba PREPILIN-TYPE
CLEAVAGE/METHYLATION
N-TERMINAL DOMAIN
PROTEIN

(Neisseria
subflava) 		PF16732
(ComP_DUS) 		3 ALA A  93
ARG A  86
LYS A  68
 None
 0.89A 3kp3B-2nbaA:
undetectable		 3kp3B-2nbaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1o PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE

(Cryptosporidium
parvum) 		PF00348
(polyprenyl_synt) 		3 ALA A 266
ARG A 271
LYS A 273
 None
None
MG  A 502 ( 4.5A)
 1.03A 3kp3B-2o1oA:
2.7		 3kp3B-2o1oA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4g HYPOTHETICAL PROTEIN

(Corynebacterium
diphtheriae) 		PF01872
(RibD_C) 		3 ALA A 184
ARG A 185
LYS A 110
 None
None
EDO  A 285 (-3.8A)
 0.98A 3kp3B-2p4gA:
undetectable		 3kp3B-2p4gA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qg7 ETHANOLAMINE KINASE
PV091845

(Plasmodium
vivax) 		PF01633
(Choline_kinase) 		3 ALA A 361
ARG A 360
LYS A 207
 None
 0.79A 3kp3B-2qg7A:
undetectable		 3kp3B-2qg7A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qm3 PREDICTED
METHYLTRANSFERASE

(Pyrococcus
furiosus) 		PF01861
(DUF43) 		3 ALA A  50
ARG A 299
LYS A 302
 None
 0.91A 3kp3B-2qm3A:
6.2		 3kp3B-2qm3A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsf DNA REPAIR PROTEIN
RAD4

(Saccharomyces
cerevisiae) 		PF03835
(Rad4)
PF10403
(BHD_1)
PF10405
(BHD_3) 		3 ALA A 280
ARG A 368
LYS A 369
 None
 0.90A 3kp3B-2qsfA:
1.3		 3kp3B-2qsfA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r77 PHOSPHATIDYLETHANOLA
MINE-BINDING
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF01161
(PBP) 		3 ALA A  52
ARG A  72
LYS A 121
 None
 1.05A 3kp3B-2r77A:
undetectable		 3kp3B-2r77A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rpb HYPOTHETICAL
MEMBRANE PROTEIN

(Pyrococcus
horikoshii) 		PF01145
(Band_7) 		3 ALA A 144
ARG A 147
LYS A 160
 None
 1.03A 3kp3B-2rpbA:
undetectable		 3kp3B-2rpbA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ALA A 460
ARG A 454
LYS A 128
 None
 1.04A 3kp3B-2v6oA:
undetectable		 3kp3B-2v6oA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB

(Streptococcus
pneumoniae) 		no annotation 3 ALA A  70
ARG A  35
LYS A   0
 None
 1.04A 3kp3B-2wjfA:
undetectable		 3kp3B-2wjfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25

(Homo sapiens) 		PF00069
(Pkinase) 		3 ALA A 118
ARG A 122
LYS A 126
 None
None
EDO  A1293 (-4.2A)
 0.60A 3kp3B-2xikA:
undetectable		 3kp3B-2xikA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3s TAML

(Streptomyces
sp. 307-9) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 ALA A 328
ARG A 323
LYS A 107
 None
GOL  A1501 (-4.5A)
GOL  A1501 (-4.5A)
 1.04A 3kp3B-2y3sA:
undetectable		 3kp3B-2y3sA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus) 		PF00148
(Oxidored_nitro)
PF08369
(PCP_red) 		3 ALA C  56
ARG D 381
LYS D 362
 None
 0.97A 3kp3B-2ynmC:
undetectable		 3kp3B-2ynmC:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbv UNCHARACTERIZED
CONSERVED PROTEIN

(Thermotoga
maritima) 		PF01887
(SAM_adeno_trans) 		3 ALA A  18
ARG A 129
LYS A 119
 None
 0.98A 3kp3B-2zbvA:
undetectable		 3kp3B-2zbvA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8b CYSQ, SULFITE
SYNTHESIS PATHWAY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF00459
(Inositol_P) 		3 ALA A 230
ARG A 233
LYS A 265
 None
 1.00A 3kp3B-3b8bA:
undetectable		 3kp3B-3b8bA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkn BACTERIOFERRITIN

(Mycolicibacterium
smegmatis) 		PF00210
(Ferritin) 		3 ALA A  46
ARG A  45
LYS A  30
 None
 0.90A 3kp3B-3bknA:
undetectable		 3kp3B-3bknA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bol 5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE

(Thermotoga
maritima) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		3 ALA A 403
ARG A 402
LYS A 429
 None
 0.84A 3kp3B-3bolA:
undetectable		 3kp3B-3bolA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB9

(Schizosaccharomyces
pombe) 		PF00623
(RNA_pol_Rpb1_2)
PF01096
(TFIIS_C)
PF02150
(RNA_POL_M_15KD)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 ALA A1152
ARG I  45
LYS I  42
 None
 1.05A 3kp3B-3h0gA:
undetectable		 3kp3B-3h0gA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1c DIISOPROPYL-FLUOROPH
OSPHATASE

(Loligo vulgaris) 		PF08450
(SGL) 		3 ALA A 142
ARG A 115
LYS A 109
 None
 1.03A 3kp3B-3i1cA:
undetectable		 3kp3B-3i1cA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP

(Escherichia
coli) 		PF07813
(LTXXQ) 		3 ALA A 108
ARG A 109
LYS A  40
 None
 1.00A 3kp3B-3itfA:
2.5		 3kp3B-3itfA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ld2 PUTATIVE
ACETYLTRANSFERASE

(Streptococcus
mutans) 		PF00583
(Acetyltransf_1) 		3 ALA A  95
ARG A  94
LYS A 128
 None
None
COA  A 164 (-2.9A)
 1.04A 3kp3B-3ld2A:
undetectable		 3kp3B-3ld2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mqt MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Shewanella
pealeana) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ALA A 163
ARG A 166
LYS A 355
 None
 0.94A 3kp3B-3mqtA:
undetectable		 3kp3B-3mqtA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9v UNCHARACTERIZED
PROTEIN

(Marinobacter
hydrocarbonoclasticus) 		PF10604
(Polyketide_cyc2) 		3 ALA A  69
ARG A  51
LYS A  41
 None
 0.92A 3kp3B-3p9vA:
undetectable		 3kp3B-3p9vA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ALA A   9
ARG A   6
LYS A   4
 None
 1.05A 3kp3B-3pocA:
undetectable		 3kp3B-3pocA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rq1 AMINOTRANSFERASE
CLASS I AND II

(Veillonella
parvula) 		PF00155
(Aminotran_1_2) 		3 ALA A 106
ARG A 267
LYS A 259
 None
OAA  A 422 (-3.7A)
OAA  A 422 (-2.8A)
 0.96A 3kp3B-3rq1A:
1.4		 3kp3B-3rq1A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrk V-TYPE ATPASE 116
KDA SUBUNIT

(Meiothermus
ruber) 		no annotation 3 ALA A 160
ARG A 162
LYS A 181
 None
None
NHE  A 520 (-3.2A)
 0.77A 3kp3B-3rrkA:
undetectable		 3kp3B-3rrkA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slu M23 PEPTIDASE DOMAIN
PROTEIN

(Neisseria
meningitidis) 		PF01551
(Peptidase_M23) 		3 ALA A  89
ARG A  90
LYS A 140
 None
 1.00A 3kp3B-3sluA:
undetectable		 3kp3B-3sluA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unv ADMH

(Pantoea
agglomerans) 		PF00221
(Lyase_aromatic) 		3 ALA A 466
ARG A 470
LYS A 474
 None
 0.91A 3kp3B-3unvA:
0.8		 3kp3B-3unvA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL

(Arabidopsis
thaliana) 		PF00498
(FHA) 		3 ALA A  10
ARG A  11
LYS A  81
 None
 1.01A 3kp3B-3vpyA:
undetectable		 3kp3B-3vpyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wyz RIBONUCLEASE P
PROTEIN COMPONENT 3

(Thermococcus
kodakarensis) 		PF01876
(RNase_P_p30) 		3 ALA A 153
ARG A 157
LYS A 161
 None
 0.55A 3kp3B-3wyzA:
undetectable		 3kp3B-3wyzA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ha4 BETA-GALACTOSIDASE

(Acidilobus
saccharovorans) 		PF00232
(Glyco_hydro_1) 		3 ALA A 457
ARG A 461
LYS A 465
 None
SIN  A 502 (-3.7A)
SIN  A 502 (-2.7A)
 0.99A 3kp3B-4ha4A:
undetectable		 3kp3B-4ha4A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1i MALATE DEHYDROGENASE

(Leishmania
major) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ALA A   7
ARG A  38
LYS A  66
 None
 0.96A 3kp3B-4i1iA:
undetectable		 3kp3B-4i1iA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l39 4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12

(Arabidopsis
thaliana) 		PF03321
(GH3) 		3 ALA A  86
ARG A  87
LYS A 111
 None
 0.79A 3kp3B-4l39A:
undetectable		 3kp3B-4l39A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7

(Saccharomyces
cerevisiae) 		PF01423
(LSM) 		3 ALA F 105
ARG F  39
LYS F  41
 None
 1.03A 3kp3B-4m7aF:
undetectable		 3kp3B-4m7aF:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mxt UNCHARACTERIZED
PROTEIN

(Bacteroides
uniformis) 		PF16584
(LolA_2) 		3 ALA A 148
ARG A 126
LYS A 128
 None
 0.92A 3kp3B-4mxtA:
undetectable		 3kp3B-4mxtA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF00007
(Cys_knot)
PF13416
(SBP_bac_8) 		3 ALA A1105
ARG A1107
LYS A1058
 None
 1.06A 3kp3B-4my2A:
undetectable		 3kp3B-4my2A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n30 PROTEIN DISULFIDE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13462
(Thioredoxin_4) 		3 ALA A 158
ARG A 107
LYS A 169
 None
 1.04A 3kp3B-4n30A:
undetectable		 3kp3B-4n30A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n40 PROTEIN ECT2

(Homo sapiens) 		PF00533
(BRCT)
PF12738
(PTCB-BRCT) 		3 ALA A 227
ARG A 232
LYS A 236
 None
 1.03A 3kp3B-4n40A:
undetectable		 3kp3B-4n40A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nph PROBABLE SECRETION
SYSTEM APPARATUS ATP
SYNTHASE SSAN

(Salmonella
enterica) 		PF00006
(ATP-synt_ab) 		3 ALA A 145
ARG A 144
LYS A 426
 None
 0.88A 3kp3B-4nphA:
undetectable		 3kp3B-4nphA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o27 SERINE/THREONINE-PRO
TEIN KINASE 24

(Homo sapiens) 		PF00069
(Pkinase) 		3 ALA B 122
ARG B 126
LYS B 130
 None
 1.02A 3kp3B-4o27B:
undetectable		 3kp3B-4o27B:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppu CHORISMATE MUTASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 3 ALA A 272
ARG A 276
LYS A 280
 None
 0.73A 3kp3B-4ppuA:
undetectable		 3kp3B-4ppuA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3z AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 1

(Homo sapiens) 		no annotation 3 ALA A   6
ARG A  10
LYS A  14
 None
 1.06A 3kp3B-4r3zA:
undetectable		 3kp3B-4r3zA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4re2 BETA-MANNOSIDASE/BET
A-GLUCOSIDASE

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		3 ALA A 224
ARG A 228
LYS A 232
 None
 0.76A 3kp3B-4re2A:
undetectable		 3kp3B-4re2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3p 4-ALPHA-GLUCANOTRANS
FERASE

(Escherichia
coli) 		PF02446
(Glyco_hydro_77) 		3 ALA A 532
ARG A 531
LYS A 518
 None
 0.97A 3kp3B-4s3pA:
undetectable		 3kp3B-4s3pA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3j PROTEIN STU2

(Saccharomyces
cerevisiae) 		no annotation 3 ALA C 517
ARG C 519
LYS C 549
 None
 1.01A 3kp3B-4u3jC:
undetectable		 3kp3B-4u3jC:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uup MALATE DEHYDROGENASE

(synthetic
construct) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ALA A 245
ARG A  23
LYS A  26
 None
 1.05A 3kp3B-4uupA:
undetectable		 3kp3B-4uupA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8x CRISPR SYSTEM CMR
SUBUNIT CMR1-1

(Pyrococcus
furiosus) 		PF03787
(RAMPs) 		3 ALA A  42
ARG A  41
LYS A  56
 None
 0.93A 3kp3B-4w8xA:
undetectable		 3kp3B-4w8xA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa2 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MBP-PILA: C

(Acinetobacter
baumannii;
Escherichia
coli) 		PF00114
(Pilin)
PF13416
(SBP_bac_8) 		3 ALA A1120
ARG A1122
LYS A1124
 None
 0.97A 3kp3B-4xa2A:
undetectable		 3kp3B-4xa2A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xri PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		3 ALA A 856
ARG A 860
LYS A 864
 None
 0.74A 3kp3B-4xriA:
undetectable		 3kp3B-4xriA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xrs HOMEOBOX PROTEIN
DLX-3

(Homo sapiens) 		PF00046
(Homeobox) 		3 ALA G 142
ARG G 146
LYS G 150
 None
 1.01A 3kp3B-4xrsG:
undetectable		 3kp3B-4xrsG:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0z CHOLINE
TRIMETHYLAMINE LYASE

(Klebsiella
pneumoniae) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ALA A 736
ARG A 705
LYS A 729
 None
 0.80A 3kp3B-5a0zA:
undetectable		 3kp3B-5a0zA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ahm INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00478
(IMPDH) 		3 ALA A 238
ARG A  84
LYS A  88
 None
 1.03A 3kp3B-5ahmA:
undetectable		 3kp3B-5ahmA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anc RIBOSOME MATURATION
PROTEIN SBDS

(Homo sapiens) 		PF01172
(SBDS)
PF09377
(SBDS_C) 		3 ALA J  23
ARG J  22
LYS J  90
 None
 0.81A 3kp3B-5ancJ:
undetectable		 3kp3B-5ancJ:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c16 MYOTUBULARIN-RELATED
PROTEIN 1

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		3 ALA A 493
ARG A 497
LYS A 177
 None
 1.03A 3kp3B-5c16A:
undetectable		 3kp3B-5c16A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwe CYTOCHROME P450
HYDROXYLASE

(Streptomyces
avermitilis) 		PF00067
(p450) 		3 ALA A  56
ARG A 286
LYS A  64
 None
HEM  A 403 (-2.8A)
HEM  A 403 ( 4.2A)
 0.89A 3kp3B-5cweA:
undetectable		 3kp3B-5cweA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A

(Cellvibrio
japonicus) 		no annotation 3 ALA A 562
ARG A 603
LYS A 643
 None
 1.03A 3kp3B-5fkrA:
undetectable		 3kp3B-5fkrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnm VITAMIN D(3)
25-HYDROXYLASE

(Pseudonocardia
autotrophica) 		PF00067
(p450) 		3 ALA A  57
ARG A 289
LYS A  65
 None
HEM  A 501 (-2.7A)
HEM  A 501 (-2.6A)
 0.85A 3kp3B-5gnmA:
undetectable		 3kp3B-5gnmA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		3 ALA b 100
ARG b 104
LYS b 108
 None
 0.78A 3kp3B-5gw5b:
2.3		 3kp3B-5gw5b:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h69 CHROMOSOME PARTITION
PROTEIN SMC

(Geobacillus
stearothermophilus) 		PF06470
(SMC_hinge) 		3 ALA A 479
ARG A 483
LYS A 487
 None
 0.76A 3kp3B-5h69A:
undetectable		 3kp3B-5h69A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvo ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)

(Aspergillus
fumigatus) 		PF00982
(Glyco_transf_20) 		3 ALA A 371
ARG A 268
LYS A 275
 None
 0.81A 3kp3B-5hvoA:
undetectable		 3kp3B-5hvoA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikg DYE-DECOLORIZING
PEROXIDASE

(Auricularia
auricula-judae) 		PF04261
(Dyp_perox) 		3 ALA A 303
ARG A 306
LYS A 387
 None
 1.03A 3kp3B-5ikgA:
undetectable		 3kp3B-5ikgA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iud DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 ALA A1221
ARG A1222
LYS A1054
 None
 1.05A 3kp3B-5iudA:
undetectable		 3kp3B-5iudA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kum ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 12

(Gallus gallus) 		PF01007
(IRK) 		3 ALA A 182
ARG A 186
LYS A 188
 None
PIO  A 401 (-3.5A)
PIO  A 401 (-2.8A)
 0.94A 3kp3B-5kumA:
2.3		 3kp3B-5kumA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kum ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 12

(Gallus gallus) 		PF01007
(IRK) 		3 ALA A 182
ARG A 186
LYS A 189
 None
PIO  A 401 (-3.5A)
PIO  A 401 (-2.7A)
 1.03A 3kp3B-5kumA:
2.3		 3kp3B-5kumA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ltg AUTOPHAGY-RELATED
PROTEIN 18

(Ogataea angusta) 		no annotation 3 ALA A 240
ARG A 248
LYS A 257
 None
FLC  A 602 (-3.2A)
None
 1.04A 3kp3B-5ltgA:
undetectable		 3kp3B-5ltgA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdu RPB7-BINDING PROTEIN
SEB1

(Schizosaccharomyces
pombe) 		PF00076
(RRM_1) 		3 ALA A 453
ARG A 450
LYS A 387
 CL  A 601 ( 4.4A)
None
None
 1.02A 3kp3B-5mduA:
undetectable		 3kp3B-5mduA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg5 HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Pseudomonas
protegens) 		no annotation 3 ALA A  62
ARG A  65
LYS A 327
 None
 0.92A 3kp3B-5mg5A:
undetectable		 3kp3B-5mg5A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxy OSMOTICALLY
ACTIVATED
L-CARNITINE/CHOLINE
ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN OPUCC

(Bacillus
subtilis) 		no annotation 3 ALA A  85
ARG A  89
LYS A  93
 None
 0.79A 3kp3B-5nxyA:
undetectable		 3kp3B-5nxyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opt 40S RIBOSOMAL
PROTEIN S6

(Trypanosoma
cruzi) 		no annotation 3 ALA P 186
ARG P 190
LYS P 194
 None
C  E 318 ( 3.1A)
A  E 315 ( 3.0A)
 0.76A 3kp3B-5optP:
undetectable		 3kp3B-5optP:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE

(Pseudomonas
aeruginosa) 		no annotation 3 ALA A  78
ARG A  82
LYS A  86
 None
 0.54A 3kp3B-5uxnA:
undetectable		 3kp3B-5uxnA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vye L-THREONINE ALDOLASE

(Pseudomonas
putida) 		no annotation 3 ALA A 289
ARG A 177
LYS A 207
 None
PLR  A 401 (-3.9A)
PLR  A 401 (-2.3A)
 0.93A 3kp3B-5vyeA:
undetectable		 3kp3B-5vyeA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 3 ALA A 936
ARG A 935
LYS A  20
 None
A  B  -6 ( 4.4A)
A  B  -6 ( 4.6A)
 0.89A 3kp3B-5wlhA:
0.6		 3kp3B-5wlhA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xeb ENVELOPE
GLYCOPROTEIN

(Dhori
thogotovirus) 		PF03273
(Baculo_gp64) 		3 ALA A 185
ARG A 173
LYS A 305
 None
 1.04A 3kp3B-5xebA:
undetectable		 3kp3B-5xebA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfh SALT STRESS-INDUCED
PROTEIN

(Oryza sativa) 		no annotation 3 ALA A  36
ARG A  38
LYS A  62
 None
 0.91A 3kp3B-5xfhA:
undetectable		 3kp3B-5xfhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis) 		PF00164
(Ribosom_S12_S23) 		3 ALA X  12
ARG X  16
LYS X  20
 None
None
C  2 242 ( 4.4A)
 0.66A 3kp3B-5xyiX:
undetectable		 3kp3B-5xyiX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 3 ALA A 406
ARG A 410
LYS A 414
 None
 0.84A 3kp3B-5yxeA:
undetectable		 3kp3B-5yxeA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zji PHOTOSYSTEM I
REACTION CENTER
SUBUNIT PSAK

(Zea mays) 		no annotation 3 ALA K  75
ARG K  77
LYS K  84
 None
 1.01A 3kp3B-5zjiK:
undetectable		 3kp3B-5zjiK:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aoo MALATE DEHYDROGENASE

(Haemophilus
influenzae) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ALA A 232
ARG A 236
LYS A 240
 None
 0.80A 3kp3B-6aooA:
undetectable		 3kp3B-6aooA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfz DAD2

(Chaetomium
thermophilum) 		no annotation 3 ALA C  27
ARG C  31
LYS C  35
 None
 0.66A 3kp3B-6cfzC:
undetectable		 3kp3B-6cfzC:
23.57