SIMILAR PATTERNS OF AMINO ACIDS FOR 3KO0_K_TFPK201
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aoh | CELLULOSOMAL-SCAFFOLDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 4 | ILE A 23PHE A 27PHE A 82PHE A 40 | None | 1.05A | 3ko0K-1aohA:undetectable3ko0S-1aohA:undetectable | 3ko0K-1aohA:19.213ko0S-1aohA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1att | ANTITHROMBIN III (Bos taurus) |
PF00079(Serpin) | 4 | ILE A 389PHE A 124PHE A 107PHE A 109 | None | 1.04A | 3ko0K-1attA:0.33ko0S-1attA:0.3 | 3ko0K-1attA:11.813ko0S-1attA:11.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8b | SPORE PROTEASE (Bacillusmegaterium) |
PF03418(Peptidase_A25) | 4 | GLY A 620ILE A 742MET A 745PHE A 496 | None | 0.99A | 3ko0K-1c8bA:undetectable3ko0S-1c8bA:undetectable | 3ko0K-1c8bA:13.753ko0S-1c8bA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbi | AK.1 SERINE PROTEASE (Bacillus sp.Ak1) |
PF00082(Peptidase_S8) | 4 | GLY A 183ILE A 210MET A 222PHE A 194 | None | 0.70A | 3ko0K-1dbiA:undetectable3ko0S-1dbiA:undetectable | 3ko0K-1dbiA:15.023ko0S-1dbiA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ehy | PROTEIN (SOLUBLEEPOXIDE HYDROLASE) (Agrobacteriumtumefaciens) |
PF00561(Abhydrolase_1) | 4 | GLY A 37ILE A 219PHE A 155PHE A 179 | None | 0.98A | 3ko0K-1ehyA:0.23ko0S-1ehyA:0.7 | 3ko0K-1ehyA:15.523ko0S-1ehyA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5x | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Thermotogamaritima) |
PF01380(SIS) | 4 | ILE A 155MET A 154PHE A 19PHE A 22 | None | 0.95A | 3ko0K-1j5xA:undetectable3ko0S-1j5xA:undetectable | 3ko0K-1j5xA:15.983ko0S-1j5xA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | GLY A2825PHE A2636PHE A2600PHE A2647 | None | 0.99A | 3ko0K-1js8A:undetectable3ko0S-1js8A:undetectable | 3ko0K-1js8A:13.473ko0S-1js8A:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofm | CHONDROITINASE B (Pedobacterheparinus) |
PF14592(Chondroitinas_B) | 4 | GLY A 119ILE A 162CYH A 203PHE A 204 | None | 1.03A | 3ko0K-1ofmA:undetectable3ko0S-1ofmA:undetectable | 3ko0K-1ofmA:10.863ko0S-1ofmA:10.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi9 | PROTEIN (VANADIUMBROMOPEROXIDASE) (Ascophyllumnodosum) |
no annotation | 4 | GLY A 417ILE A 492PHE A 195PHE A 207 | VO4 A 600 (-3.8A)NoneNoneNone | 0.91A | 3ko0K-1qi9A:0.03ko0S-1qi9A:0.0 | 3ko0K-1qi9A:11.133ko0S-1qi9A:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 4 | GLY A 95ILE A 282PHE A 422PHE A 425 | HEA A 601 ( 4.0A)HEA A 602 ( 4.7A)NoneNone | 1.05A | 3ko0K-1qleA:undetectable3ko0S-1qleA:undetectable | 3ko0K-1qleA:10.653ko0S-1qleA:10.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwy | PEPTIDOGLYCANHYDROLASE (Staphylococcusaureus) |
PF01551(Peptidase_M23) | 4 | GLY A 65ILE A 53PHE A 81PHE A 91 | None | 0.92A | 3ko0K-1qwyA:undetectable3ko0S-1qwyA:undetectable | 3ko0K-1qwyA:11.343ko0S-1qwyA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sg3 | ALLANTOICASE (Saccharomycescerevisiae) |
PF03561(Allantoicase) | 4 | GLY A 27ILE A 95PHE A 141PHE A 178 | None | 0.97A | 3ko0K-1sg3A:undetectable3ko0S-1sg3A:undetectable | 3ko0K-1sg3A:15.343ko0S-1sg3A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6n | PROBABLEATP-DEPENDENT RNAHELICASE (Homo sapiens) |
PF00270(DEAD) | 4 | GLY A 46ILE A 80PHE A 99PHE A 227 | None | 0.95A | 3ko0K-1t6nA:0.03ko0S-1t6nA:0.0 | 3ko0K-1t6nA:18.183ko0S-1t6nA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t70 | PHOSPHATASE (Deinococcusradiodurans) |
PF13277(YmdB) | 4 | GLY A 187ILE A 170PHE A 31PHE A 239 | None | 1.05A | 3ko0K-1t70A:undetectable3ko0S-1t70A:undetectable | 3ko0K-1t70A:15.943ko0S-1t70A:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tba | TRANSCRIPTIONINITIATION FACTORIID 230K CHAINTRANSCRIPTIONINITIATION FACTORTFIID (Drosophilamelanogaster;Saccharomycescerevisiae) |
PF00352(TBP)PF09247(TBP-binding) | 4 | GLY A 57ILE B 194PHE A 25PHE A 48 | None | 0.93A | 3ko0K-1tbaA:undetectable3ko0S-1tbaA:undetectable | 3ko0K-1tbaA:21.693ko0S-1tbaA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ted | PKS18 (Mycobacteriumtuberculosis) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | GLY A 288ILE A 304PHE A 388PHE A 375 | GLY A 288 ( 0.0A)ILE A 304 ( 0.7A)PHE A 388 ( 1.3A)PHE A 375 ( 1.3A) | 0.95A | 3ko0K-1tedA:0.03ko0S-1tedA:0.0 | 3ko0K-1tedA:11.963ko0S-1tedA:11.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5l | PRION PROTEIN (Trachemysscripta) |
PF00377(Prion) | 4 | GLY A 123ILE A 210MET A 213CYH A 214 | None | 0.79A | 3ko0K-1u5lA:undetectable3ko0S-1u5lA:0.4 | 3ko0K-1u5lA:18.753ko0S-1u5lA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5l | PRION PROTEIN (Trachemysscripta) |
PF00377(Prion) | 4 | GLY A 124ILE A 210MET A 213CYH A 214 | None | 0.93A | 3ko0K-1u5lA:undetectable3ko0S-1u5lA:0.4 | 3ko0K-1u5lA:18.753ko0S-1u5lA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY A 10ILE A 255PHE A 81PHE A 287 | None | 0.97A | 3ko0K-1vmaA:2.43ko0S-1vmaA:2.6 | 3ko0K-1vmaA:14.053ko0S-1vmaA:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | GLY A 89PHE A 95PHE A 120PHE A 82 | None | 1.03A | 3ko0K-1xc6A:undetectable3ko0S-1xc6A:undetectable | 3ko0K-1xc6A:6.853ko0S-1xc6A:6.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xtj | PROBABLEATP-DEPENDENT RNAHELICASE P47 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | GLY A 46ILE A 80PHE A 99PHE A 227 | None | 1.05A | 3ko0K-1xtjA:0.03ko0S-1xtjA:0.0 | 3ko0K-1xtjA:13.393ko0S-1xtjA:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z45 | GAL10 BIFUNCTIONALPROTEIN (Saccharomycescerevisiae) |
PF01263(Aldose_epim)PF16363(GDP_Man_Dehyd) | 4 | GLY A 424ILE A 694PHE A 540PHE A 662 | None | 0.96A | 3ko0K-1z45A:undetectable3ko0S-1z45A:undetectable | 3ko0K-1z45A:9.593ko0S-1z45A:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ae8 | IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (Staphylococcusaureus) |
PF00475(IGPD) | 4 | GLY A 73ILE A 51PHE A 127PHE A 135 | None | 0.95A | 3ko0K-2ae8A:1.43ko0S-2ae8A:1.3 | 3ko0K-2ae8A:14.683ko0S-2ae8A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | GLY I 339PHE I 123PHE I 106PHE I 108 | None | 0.90A | 3ko0K-2b4xI:0.03ko0S-2b4xI:0.0 | 3ko0K-2b4xI:15.123ko0S-2b4xI:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | ILE I 420PHE I 106PHE I 108PHE I 123 | None | 0.91A | 3ko0K-2b4xI:0.03ko0S-2b4xI:0.0 | 3ko0K-2b4xI:15.123ko0S-2b4xI:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bfw | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1) | 4 | GLY A 308ILE A 288MET A 253PHE A 331 | None | 0.94A | 3ko0K-2bfwA:0.93ko0S-2bfwA:undetectable | 3ko0K-2bfwA:19.003ko0S-2bfwA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ccl | CELLULOSOMALSCAFFOLDING PROTEINA (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 4 | ILE A 23PHE A 27PHE A 82PHE A 40 | None | 0.98A | 3ko0K-2cclA:undetectable3ko0S-2cclA:undetectable | 3ko0K-2cclA:20.133ko0S-2cclA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g3n | ALPHA-GLUCOSIDASE (Sulfolobussolfataricus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 4 | GLY A 447ILE A 181PHE A 396PHE A 476 | None | 0.99A | 3ko0K-2g3nA:undetectable3ko0S-2g3nA:undetectable | 3ko0K-2g3nA:11.283ko0S-2g3nA:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gyq | YCFI, PUTATIVESTRUCTURAL PROTEIN (Rhodopseudomonaspalustris) |
PF05974(DUF892) | 4 | GLY A 76ILE A 22PHE A 139PHE A 67 | None | 0.89A | 3ko0K-2gyqA:1.43ko0S-2gyqA:1.4 | 3ko0K-2gyqA:19.253ko0S-2gyqA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h57 | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN6 (Homo sapiens) |
PF00025(Arf) | 4 | GLY A 167ILE A 34CYH A 22PHE A 92 | None | 1.02A | 3ko0K-2h57A:0.03ko0S-2h57A:0.0 | 3ko0K-2h57A:18.653ko0S-2h57A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hne | L-FUCONATEDEHYDRATASE (Xanthomonascampestris) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 356ILE A 419PHE A 429PHE A 14 | None | 0.95A | 3ko0K-2hneA:undetectable3ko0S-2hneA:undetectable | 3ko0K-2hneA:13.633ko0S-2hneA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpi | DNA POLYMERASE IIIALPHA SUBUNIT (Thermusaquaticus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 4 | GLY A 174ILE A 277MET A 280CYH A 281 | None | 0.58A | 3ko0K-2hpiA:0.53ko0S-2hpiA:undetectable | 3ko0K-2hpiA:6.273ko0S-2hpiA:6.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jok | PUTATIVEG-NUCLEOTIDEEXCHANGE FACTOR (Burkholderiapseudomallei) |
PF07487(SopE_GEF) | 4 | GLY A 171MET A 132CYH A 131PHE A 130 | None | 1.05A | 3ko0K-2jokA:undetectable3ko0S-2jokA:undetectable | 3ko0K-2jokA:17.203ko0S-2jokA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l26 | UNCHARACTERIZEDPROTEINRV0899/MT0922 (Mycobacteriumtuberculosis) |
PF00691(OmpA)PF04972(BON) | 4 | GLY A 164ILE A 188PHE A 135PHE A 142 | None | 0.92A | 3ko0K-2l26A:undetectable3ko0S-2l26A:undetectable | 3ko0K-2l26A:13.843ko0S-2l26A:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5r | GLUTAMYL-TRNASYNTHETASE 1 (Thermotogamaritima) |
PF00749(tRNA-synt_1c) | 4 | ILE A 330PHE A 379PHE A 371PHE A 341 | None | 0.89A | 3ko0K-2o5rA:undetectable3ko0S-2o5rA:undetectable | 3ko0K-2o5rA:12.333ko0S-2o5rA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5r | GLUTAMYL-TRNASYNTHETASE 1 (Thermotogamaritima) |
PF00749(tRNA-synt_1c) | 4 | PHE A 378PHE A 379PHE A 371PHE A 341 | None | 1.05A | 3ko0K-2o5rA:undetectable3ko0S-2o5rA:undetectable | 3ko0K-2o5rA:12.333ko0S-2o5rA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfk | 6-PHOSPHOFRUCTOKINASE ISOZYME I (Escherichiacoli) |
PF00365(PFK) | 4 | GLY A 101ILE A 296PHE A 117PHE A 76 | None | 1.03A | 3ko0K-2pfkA:undetectable3ko0S-2pfkA:undetectable | 3ko0K-2pfkA:14.203ko0S-2pfkA:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euw | MYO-INOSITOLDEHYDROGENASE (Corynebacteriumglutamicum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 111ILE A 96CYH A 92PHE A 291 | None | 0.95A | 3ko0K-3euwA:undetectable3ko0S-3euwA:undetectable | 3ko0K-3euwA:11.923ko0S-3euwA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1w | MANNOSE-6-PHOSPHATEISOMERASE (Salmonellaenterica) |
PF01238(PMI_typeI) | 4 | ILE A 335PHE A 344PHE A 85PHE A 323 | None | 0.76A | 3ko0K-3h1wA:undetectable3ko0S-3h1wA:undetectable | 3ko0K-3h1wA:12.283ko0S-3h1wA:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn5 | PUTATIVE EXPORTEDPROTEIN BF0290 (Bacteroidesfragilis) |
PF12866(DUF3823) | 4 | GLY A 149ILE A 227CYH A 217PHE A 192 | None | 0.87A | 3ko0K-3hn5A:undetectable3ko0S-3hn5A:undetectable | 3ko0K-3hn5A:12.963ko0S-3hn5A:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if9 | GLYCINE OXIDASE (Bacillussubtilis) |
PF01266(DAO) | 4 | GLY A 308ILE A 361PHE A 209PHE A 219 | NoneNoneFAD A 371 (-4.7A)None | 0.93A | 3ko0K-3if9A:undetectable3ko0S-3if9A:undetectable | 3ko0K-3if9A:13.233ko0S-3if9A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | GLY A 227ILE A 254MET A 273PHE A 238 | None | 0.81A | 3ko0K-3lpdA:undetectable3ko0S-3lpdA:undetectable | 3ko0K-3lpdA:12.683ko0S-3lpdA:12.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxz | GLUTATHIONES-TRANSFERASE FAMILYPROTEIN (Pseudomonasputida) |
PF13417(GST_N_3)PF14497(GST_C_3) | 4 | GLY A 169PHE A 142PHE A 133PHE A 181 | None | 0.93A | 3ko0K-3lxzA:undetectable3ko0S-3lxzA:undetectable | 3ko0K-3lxzA:19.653ko0S-3lxzA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myr | HYDROGENASE (NIFE)SMALL SUBUNIT HYDANICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Allochromatiumvinosum) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | GLY A 76ILE B1041PHE A 263PHE A 257 | SF4 A2001 ( 4.6A)NoneNoneNone | 0.95A | 3ko0K-3myrA:undetectable3ko0S-3myrA:undetectable | 3ko0K-3myrA:17.523ko0S-3myrA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6z | PUTATIVEIMMUNOGLOBULIN A1PROTEASE (Bacteroidesovatus) |
no annotation | 4 | GLY A 173ILE A 204CYH A 222PHE A 251 | None | 1.02A | 3ko0K-3n6zA:undetectable3ko0S-3n6zA:undetectable | 3ko0K-3n6zA:15.103ko0S-3n6zA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nix | FLAVOPROTEIN/DEHYDROGENASE (Cytophagahutchinsonii) |
PF01494(FAD_binding_3) | 4 | GLY A 358ILE A 303PHE A 231PHE A 238 | None | 0.86A | 3ko0K-3nixA:undetectable3ko0S-3nixA:undetectable | 3ko0K-3nixA:14.323ko0S-3nixA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opn | PUTATIVE HEMOLYSIN (Lactococcuslactis) |
PF01728(FtsJ) | 4 | GLY A 150ILE A 128PHE A 108PHE A 118 | None | 0.95A | 3ko0K-3opnA:undetectable3ko0S-3opnA:undetectable | 3ko0K-3opnA:16.383ko0S-3opnA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgu | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydomonasreinhardtii) |
PF00155(Aminotran_1_2) | 4 | GLY A 438ILE A 393PHE A 414PHE A 366 | None | 0.87A | 3ko0K-3qguA:undetectable3ko0S-3qguA:undetectable | 3ko0K-3qguA:12.443ko0S-3qguA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5v | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 4 | CYH B 65PHE B 68PHE B 90PHE B 16 | None | 0.91A | 3ko0K-3t5vB:undetectable3ko0S-3t5vB:undetectable | 3ko0K-3t5vB:13.083ko0S-3t5vB:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgj | TYROSYL-TRNASYNTHETASE, PUTATIVE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | GLY A 62MET A 259PHE A 353PHE A 120 | TYR A 401 ( 3.3A)NoneNoneNone | 0.99A | 3ko0K-3vgjA:undetectable3ko0S-3vgjA:undetectable | 3ko0K-3vgjA:15.553ko0S-3vgjA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdo | MFS TRANSPORTER (Escherichiacoli) |
PF07690(MFS_1) | 4 | GLY A 69ILE A 327PHE A 144PHE A 21 | None | 1.04A | 3ko0K-3wdoA:undetectable3ko0S-3wdoA:undetectable | 3ko0K-3wdoA:12.923ko0S-3wdoA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ziz | GH5ENDO-BETA-1,4-MANNANASE (Podosporaanserina) |
PF00150(Cellulase) | 4 | GLY A 256PHE A 237PHE A 240PHE A 226 | None | 1.04A | 3ko0K-3zizA:undetectable3ko0S-3zizA:undetectable | 3ko0K-3zizA:11.523ko0S-3zizA:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9y | ALPHA-GLUCOSIDASE,PUTATIVE, ADG31B (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF17137(DUF5110) | 4 | GLY A 47ILE A 112PHE A 135PHE A 144 | None | 0.89A | 3ko0K-4b9yA:undetectable3ko0S-4b9yA:undetectable | 3ko0K-4b9yA:7.713ko0S-4b9yA:7.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 4 | ILE A 353PHE A 366PHE A 291PHE A 193 | None | 1.03A | 3ko0K-4btpA:1.53ko0S-4btpA:1.5 | 3ko0K-4btpA:9.183ko0S-4btpA:9.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dw1 | P2X PURINOCEPTOR (Danio rerio) |
PF00864(P2X_receptor) | 4 | GLY A 253PHE A 233PHE A 322PHE A 102 | None | 0.90A | 3ko0K-4dw1A:undetectable3ko0S-4dw1A:undetectable | 3ko0K-4dw1A:13.783ko0S-4dw1A:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euf | PUTATIVE REDUCTASECA_C0462 (Clostridiumacetobutylicum) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 4 | GLY A 329ILE A 317PHE A 135PHE A 214 | None | 0.83A | 3ko0K-4eufA:undetectable3ko0S-4eufA:undetectable | 3ko0K-4eufA:13.463ko0S-4eufA:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4evq | PUTATIVE ABCTRANSPORTER SUBUNIT,SUBSTRATE-BINDINGCOMPONENT (Rhodopseudomonaspalustris) |
PF13458(Peripla_BP_6) | 4 | GLY A 369ILE A 240PHE A 257PHE A 306 | NoneNonePHB A 406 (-3.8A)PHB A 406 (-4.4A) | 0.97A | 3ko0K-4evqA:undetectable3ko0S-4evqA:undetectable | 3ko0K-4evqA:13.403ko0S-4evqA:13.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fch | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | GLY A 289PHE A 314PHE A 379PHE A 340 | None | 1.00A | 3ko0K-4fchA:undetectable3ko0S-4fchA:undetectable | 3ko0K-4fchA:15.073ko0S-4fchA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga7 | LEUKOCYTE ELASTASEINHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | GLY A 292PHE A 70PHE A 58PHE A 60 | None | 1.05A | 3ko0K-4ga7A:undetectable3ko0S-4ga7A:undetectable | 3ko0K-4ga7A:14.473ko0S-4ga7A:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 12 (Thermusthermophilus) |
PF00361(Proton_antipo_M)PF00662(Proton_antipo_N) | 4 | GLY L 508ILE L 294PHE L 532PHE L 524 | None | 0.94A | 3ko0K-4heaL:0.53ko0S-4heaL:undetectable | 3ko0K-4heaL:10.773ko0S-4heaL:10.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j75 | TRYPTOPHANYL-TRNASYNTHETASE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | ILE A 430CYH A 433PHE A 438PHE A 383 | None | 0.97A | 3ko0K-4j75A:undetectable3ko0S-4j75A:undetectable | 3ko0K-4j75A:14.443ko0S-4j75A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j75 | TRYPTOPHANYL-TRNASYNTHETASE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | ILE A 430PHE A 350PHE A 412PHE A 414 | None | 1.03A | 3ko0K-4j75A:undetectable3ko0S-4j75A:undetectable | 3ko0K-4j75A:14.443ko0S-4j75A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4joc | LYSOPHOSPHATIDICACID PHOSPHATASETYPE 6 (Homo sapiens) |
PF00328(His_Phos_2) | 4 | GLY A 136ILE A 161PHE A 304PHE A 57 | None | 0.77A | 3ko0K-4jocA:undetectable3ko0S-4jocA:undetectable | 3ko0K-4jocA:14.213ko0S-4jocA:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kt5 | GRLR (Escherichiacoli) |
PF16518(GrlR) | 4 | GLY A 34ILE A 75CYH A 90PHE A 99 | NoneNonePG4 A 201 ( 4.6A)None | 1.02A | 3ko0K-4kt5A:undetectable3ko0S-4kt5A:undetectable | 3ko0K-4kt5A:22.563ko0S-4kt5A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l2k | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | GLY A1058ILE A1039PHE A1098PHE A1061 | None | 1.00A | 3ko0K-4l2kA:undetectable3ko0S-4l2kA:undetectable | 3ko0K-4l2kA:16.753ko0S-4l2kA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oa7 | TANKYRASE-1 (Homo sapiens) |
PF00644(PARP) | 4 | GLY A1211ILE A1192PHE A1251PHE A1214 | None2XS A1402 ( 4.7A)NoneNone | 0.97A | 3ko0K-4oa7A:undetectable3ko0S-4oa7A:undetectable | 3ko0K-4oa7A:19.813ko0S-4oa7A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8b | TRAP-TYPETRANSPORTER,PERIPLASMICCOMPONENT (Cupriavidusnecator) |
PF03480(DctP) | 4 | GLY A 46ILE A 276PHE A 136PHE A 246 | None | 0.81A | 3ko0K-4p8bA:undetectable3ko0S-4p8bA:undetectable | 3ko0K-4p8bA:15.503ko0S-4p8bA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 4 | GLY A 195ILE A 210PHE A 132PHE A 119 | None | 0.72A | 3ko0K-4q22A:undetectable3ko0S-4q22A:undetectable | 3ko0K-4q22A:13.233ko0S-4q22A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6p | CONSERVEDHYPOTHETICALSECRETED PROTEIN (Helicobacterpylori) |
PF17033(Peptidase_M99)PF17129(Peptidase_M99_C)PF17130(Peptidase_M99_m) | 4 | ILE A 433PHE A 386PHE A 406PHE A 437 | None | 0.94A | 3ko0K-4q6pA:undetectable3ko0S-4q6pA:undetectable | 3ko0K-4q6pA:13.563ko0S-4q6pA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6t | GLYCOSYL HYDROLASE,FAMILY 18 (Pseudomonasprotegens) |
PF00704(Glyco_hydro_18) | 4 | GLY A 259ILE A 178PHE A 148PHE A 159 | None | 1.00A | 3ko0K-4q6tA:undetectable3ko0S-4q6tA:undetectable | 3ko0K-4q6tA:13.243ko0S-4q6tA:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qny | MITOGEN ACTIVATEDPROTEIN KINASE,PUTATIVE (Leishmaniadonovani) |
PF00069(Pkinase) | 4 | GLY A 84ILE A 139PHE A 328PHE A 168 | None | 1.05A | 3ko0K-4qnyA:undetectable3ko0S-4qnyA:undetectable | 3ko0K-4qnyA:14.043ko0S-4qnyA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2b | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Ochrobactrumanthropi) |
PF01547(SBP_bac_1) | 4 | GLY A 225ILE A 392PHE A 400PHE A 233 | None | 0.75A | 3ko0K-4r2bA:undetectable3ko0S-4r2bA:0.3 | 3ko0K-4r2bA:15.683ko0S-4r2bA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcm | METHYLATEDRNA-BINDING PROTEIN1 (Saccharomycescerevisiae) |
PF04146(YTH) | 4 | GLY A 175CYH A 213PHE A 212PHE A 290 | UNX A 405 ( 4.2A)NoneNoneNone | 1.02A | 3ko0K-4rcmA:undetectable3ko0S-4rcmA:undetectable | 3ko0K-4rcmA:22.023ko0S-4rcmA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rmx | PHI92_GP150 (Enterobacteriaphage phi92) |
no annotation | 4 | GLY A 556ILE A 638CYH A 643PHE A 615 | None | 0.87A | 3ko0K-4rmxA:undetectable3ko0S-4rmxA:undetectable | 3ko0K-4rmxA:11.523ko0S-4rmxA:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rs1 | GRANULOCYTE-MACROPHAGECOLONY-STIMULATINGFACTOR RECEPTORSUBUNIT ALPHA (Homo sapiens) |
PF09240(IL6Ra-bind) | 4 | GLY B 158ILE B 135PHE B 105PHE B 187 | None | 0.79A | 3ko0K-4rs1B:undetectable3ko0S-4rs1B:undetectable | 3ko0K-4rs1B:18.623ko0S-4rs1B:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8y | CRISPR SYSTEM CMRSUBUNIT CMR2 (Pyrococcusfuriosus) |
PF12469(DUF3692) | 4 | GLY A 847ILE A 807PHE A 791PHE A 858 | None | 0.93A | 3ko0K-4w8yA:undetectable3ko0S-4w8yA:undetectable | 3ko0K-4w8yA:9.053ko0S-4w8yA:9.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 4 | GLY A 222ILE A 120PHE A 177PHE A 154 | None | 0.91A | 3ko0K-4wxjA:undetectable3ko0S-4wxjA:undetectable | 3ko0K-4wxjA:18.463ko0S-4wxjA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | BAND 3 ANIONTRANSPORT PROTEIN (Homo sapiens) |
PF00955(HCO3_cotransp) | 4 | GLY A 714ILE A 487PHE A 478PHE A 471 | None | 0.79A | 3ko0K-4yzfA:undetectable3ko0S-4yzfA:undetectable | 3ko0K-4yzfA:8.353ko0S-4yzfA:8.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA+,K+-ATPASE BETASUBUNIT (Squalusacanthias) |
PF00287(Na_K-ATPase) | 4 | GLY B 295ILE B 263PHE B 152PHE B 240 | None | 0.95A | 3ko0K-5aw4B:undetectable3ko0S-5aw4B:undetectable | 3ko0K-5aw4B:15.743ko0S-5aw4B:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cvz | COAT PROTEIN (Panicumpapanivirus 1) |
no annotation | 4 | GLY A 51PHE A 39PHE A 60PHE A 147 | None | 0.88A | 3ko0K-5cvzA:undetectable3ko0S-5cvzA:undetectable | 3ko0K-5cvzA:16.773ko0S-5cvzA:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dcz | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | GLY A1058ILE A1039PHE A1098PHE A1061 | None | 1.02A | 3ko0K-5dczA:undetectable3ko0S-5dczA:undetectable | 3ko0K-5dczA:19.493ko0S-5dczA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dud | YBGJYBGK (Escherichiacoli) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | GLY A 254ILE B 9CYH A 260PHE A 193 | None | 0.99A | 3ko0K-5dudA:undetectable3ko0S-5dudA:undetectable | 3ko0K-5dudA:16.393ko0S-5dudA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ei0 | SERPIN A12 (Homo sapiens) |
PF00079(Serpin) | 4 | GLY A 327PHE A 116PHE A 102PHE A 104 | None | 0.90A | 3ko0K-5ei0A:undetectable3ko0S-5ei0A:undetectable | 3ko0K-5ei0A:13.453ko0S-5ei0A:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5r | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF13589(HATPase_c_3) | 4 | GLY A 162ILE A 241PHE A 209PHE A 205 | ANP A 300 ( 4.5A)NoneNoneNone | 0.88A | 3ko0K-5f5rA:undetectable3ko0S-5f5rA:undetectable | 3ko0K-5f5rA:18.223ko0S-5f5rA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 4 | GLY B 740ILE B 754PHE B 670PHE B 657 | None | 0.86A | 3ko0K-5gztB:undetectable3ko0S-5gztB:undetectable | 3ko0K-5gztB:6.273ko0S-5gztB:6.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 4 | GLY A 740ILE A 754PHE A 670PHE A 657 | None | 0.83A | 3ko0K-5gzuA:undetectable3ko0S-5gzuA:undetectable | 3ko0K-5gzuA:7.233ko0S-5gzuA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h29 | THIOREDOXINREDUCTASE/GLUTATHIONE-RELATED PROTEIN (Enterococcusfaecalis) |
no annotation | 4 | GLY A 445ILE A 441PHE A 367PHE A 397 | None | 1.03A | 3ko0K-5h29A:undetectable3ko0S-5h29A:undetectable | 3ko0K-5h29A:22.123ko0S-5h29A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hph | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF00183(HSP90)PF13589(HATPase_c_3) | 4 | GLY A 162ILE A 241PHE A 209PHE A 205 | ANP A 801 ( 4.3A)NoneNoneNone | 0.94A | 3ko0K-5hphA:undetectable3ko0S-5hphA:undetectable | 3ko0K-5hphA:11.243ko0S-5hphA:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1d | PHOSPHATE BINDINGPROTEIN (Stenotrophomonasmaltophilia) |
PF12849(PBP_like_2) | 4 | ILE A 140PHE A 192PHE A 121PHE A 188 | None | 1.01A | 3ko0K-5j1dA:undetectable3ko0S-5j1dA:undetectable | 3ko0K-5j1dA:14.483ko0S-5j1dA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | GLY A 678ILE A 567PHE A 564PHE A 656 | None | 0.98A | 3ko0K-5l46A:undetectable3ko0S-5l46A:undetectable | 3ko0K-5l46A:9.003ko0S-5l46A:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ELECTRON TRANSFERFLAVOPROTEIN LARGESUBUNITELECTRON TRANSFERFLAVOPROTEIN SMALLSUBUNIT (Clostridioidesdifficile) |
no annotation | 4 | GLY B 253ILE A 270CYH A 272PHE A 302 | None | 0.95A | 3ko0K-5ol2B:undetectable3ko0S-5ol2B:undetectable | 3ko0K-5ol2B:18.603ko0S-5ol2B:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swi | SUGAR HYDROLASE (Streptococcuspneumoniae) |
no annotation | 4 | GLY B 298PHE B 314PHE B 301PHE B 332 | None | 0.78A | 3ko0K-5swiB:undetectable3ko0S-5swiB:undetectable | 3ko0K-5swiB:10.843ko0S-5swiB:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy5 | ARYL HYDROCARBONRECEPTOR NUCLEARTRANSLOCATORNEURONAL PASDOMAIN-CONTAININGPROTEIN 1 (Mus musculus) |
PF00010(HLH)PF00989(PAS)PF08447(PAS_3)PF14598(PAS_11) | 4 | GLY B 140ILE A 178CYH A 336PHE A 335 | None | 0.97A | 3ko0K-5sy5B:undetectable3ko0S-5sy5B:undetectable | 3ko0K-5sy5B:14.733ko0S-5sy5B:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xw6 | P2X PURINOCEPTOR (Gallus gallus) |
no annotation | 4 | GLY C 237PHE C 217PHE C 304PHE C 90 | None | 0.94A | 3ko0K-5xw6C:undetectable3ko0S-5xw6C:undetectable | 3ko0K-5xw6C:13.153ko0S-5xw6C:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zxd | - (-) |
no annotation | 4 | GLY A 448ILE A 480PHE A 455PHE A 431 | None | 0.92A | 3ko0K-5zxdA:undetectable3ko0S-5zxdA:undetectable | 3ko0K-5zxdA:undetectable3ko0S-5zxdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6acd | - (-) |
no annotation | 4 | GLY A1026PHE A 782PHE A 784PHE A1034 | None | 1.04A | 3ko0K-6acdA:1.23ko0S-6acdA:1.2 | 3ko0K-6acdA:undetectable3ko0S-6acdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3b | APRAMETHYLTRANSFERASE 1 (Mooreabouillonii) |
no annotation | 4 | GLY A 133ILE A 109PHE A 156PHE A 171 | None | 1.04A | 3ko0K-6b3bA:undetectable3ko0S-6b3bA:undetectable | 3ko0K-6b3bA:9.843ko0S-6b3bA:9.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3x | CLEAVAGE STIMULATIONFACTOR SUBUNIT 1 (Homo sapiens) |
no annotation | 4 | GLY A 120ILE A 166PHE A 200PHE A 181 | None | 0.89A | 3ko0K-6b3xA:undetectable3ko0S-6b3xA:undetectable | 3ko0K-6b3xA:14.373ko0S-6b3xA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c5x | SUPPRESSOR OFCYTOKINE SIGNALLING1 (Xenopus laevis) |
no annotation | 4 | GLY D 99PHE D 209PHE D 207PHE D 79 | None | 0.80A | 3ko0K-6c5xD:undetectable3ko0S-6c5xD:undetectable | 3ko0K-6c5xD:21.783ko0S-6c5xD:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxh | PARTICULATE METHANEMONOOXYGENASE, ASUBUNITPARTICULATE METHANEMONOOXYGENASE, BSUBUNIT (Methylomicrobiumalcaliphilum) |
no annotation | 4 | GLY B 185ILE A 91MET A 141PHE A 88 | None | 0.86A | 3ko0K-6cxhB:1.13ko0S-6cxhB:1.1 | 3ko0K-6cxhB:20.753ko0S-6cxhB:20.75 |