SIMILAR PATTERNS OF AMINO ACIDS FOR 3KO0_F_TFPF201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1krh BENZOATE
1,2-DIOXYGENASE
REDUCTASE

(Acinetobacter
sp.) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 PHE A 139
PHE A 160
PHE A 109
PHE A 197
 None
 1.46A 3ko0F-1krhA:
undetectable
3ko0G-1krhA:
undetectable		 3ko0F-1krhA:
13.41
3ko0G-1krhA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq1 GLUTATHIONE
S-TRANSFERASE

(Caenorhabditis
elegans) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A 103
PHE A  99
PHE A 175
PHE A 135
 None
 1.28A 3ko0F-1yq1A:
undetectable
3ko0G-1yq1A:
undetectable		 3ko0F-1yq1A:
17.77
3ko0G-1yq1A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq1 GLUTATHIONE
S-TRANSFERASE

(Caenorhabditis
elegans) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A 175
PHE A 135
PHE A 103
PHE A  99
 None
 1.18A 3ko0F-1yq1A:
undetectable
3ko0G-1yq1A:
undetectable		 3ko0F-1yq1A:
17.77
3ko0G-1yq1A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zyb TRANSCRIPTION
REGULATOR, CRP
FAMILY

(Bacteroides
thetaiotaomicron) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 MET A 130
PHE A 125
PHE A 120
PHE A  89
 None
 1.25A 3ko0F-1zybA:
undetectable
3ko0G-1zybA:
0.0		 3ko0F-1zybA:
16.67
3ko0G-1zybA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bpa PROTEIN (SUBUNIT OF
BACTERIOPHAGE
PHIX174)

(Escherichia
virus phiX174) 		PF02306
(Phage_G) 		4 MET 2 145
PHE 2  56
PHE 2  87
PHE 2 150
 None
 1.39A 3ko0F-2bpa2:
undetectable
3ko0G-2bpa2:
undetectable		 3ko0F-2bpa2:
17.71
3ko0G-2bpa2:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2g THREONINE SYNTHASE

(Arabidopsis
thaliana) 		PF00291
(PALP) 		4 MET A 146
PHE A 143
PHE A 139
PHE A 413
 None
 1.37A 3ko0F-2c2gA:
undetectable
3ko0G-2c2gA:
0.0		 3ko0F-2c2gA:
11.97
3ko0G-2c2gA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnx HYPOTHETICAL PROTEIN

(Mus musculus) 		PF09404
(DUF2003) 		4 PHE A 422
PHE A 304
PHE A 394
PHE A 408
 None
 1.45A 3ko0F-2gnxA:
undetectable
3ko0G-2gnxA:
undetectable		 3ko0F-2gnxA:
17.15
3ko0G-2gnxA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5r GLUTAMYL-TRNA
SYNTHETASE 1

(Thermotoga
maritima) 		PF00749
(tRNA-synt_1c) 		4 PHE A 371
PHE A 341
PHE A 378
PHE A 379
 None
 1.08A 3ko0F-2o5rA:
undetectable
3ko0G-2o5rA:
0.0		 3ko0F-2o5rA:
12.33
3ko0G-2o5rA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5r GLUTAMYL-TRNA
SYNTHETASE 1

(Thermotoga
maritima) 		PF00749
(tRNA-synt_1c) 		4 PHE A 378
PHE A 379
PHE A 371
PHE A 341
 None
 1.05A 3ko0F-2o5rA:
undetectable
3ko0G-2o5rA:
0.0		 3ko0F-2o5rA:
12.33
3ko0G-2o5rA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpx PREDICTED
METAL-DEPENDENT
HYDROLASE OF THE
TIM-BARREL FOLD

(Lactobacillus
paracasei) 		PF04909
(Amidohydro_2) 		4 PHE A 332
PHE A 314
PHE A  92
PHE A  94
 None
 1.48A 3ko0F-2qpxA:
0.0
3ko0G-2qpxA:
0.0		 3ko0F-2qpxA:
14.65
3ko0G-2qpxA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyd HEMOPHORE HASA

(Serratia
marcescens) 		PF06438
(HasA) 		4 PHE X  11
PHE X 166
PHE X  94
PHE X 115
 None
 1.36A 3ko0F-2uydX:
0.6
3ko0G-2uydX:
0.7		 3ko0F-2uydX:
16.13
3ko0G-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyd HEMOPHORE HASA

(Serratia
marcescens) 		PF06438
(HasA) 		4 PHE X  94
PHE X 115
PHE X  11
PHE X 166
 None
 1.41A 3ko0F-2uydX:
0.6
3ko0G-2uydX:
0.7		 3ko0F-2uydX:
16.13
3ko0G-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8d PROCESSED GLYCEROL
PHOSPHATE
LIPOTEICHOIC ACID
SYNTHASE 2

(Bacillus
subtilis) 		PF00884
(Sulfatase) 		4 MET A 392
PHE A 365
PHE A 342
PHE A 402
 None
 1.45A 3ko0F-2w8dA:
undetectable
3ko0G-2w8dA:
undetectable		 3ko0F-2w8dA:
13.30
3ko0G-2w8dA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqp PREPROTEIN
TRANSLOCASE SECY
SUBUNIT

(Thermus
thermophilus) 		PF00344
(SecY) 		4 PHE Y 129
PHE Y 286
PHE Y 134
PHE Y  56
 None
 1.34A 3ko0F-2zqpY:
undetectable
3ko0G-2zqpY:
undetectable		 3ko0F-2zqpY:
11.03
3ko0G-2zqpY:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqp PREPROTEIN
TRANSLOCASE SECY
SUBUNIT

(Thermus
thermophilus) 		PF00344
(SecY) 		4 PHE Y 134
PHE Y  56
PHE Y 129
PHE Y 286
 None
 1.32A 3ko0F-2zqpY:
undetectable
3ko0G-2zqpY:
undetectable		 3ko0F-2zqpY:
11.03
3ko0G-2zqpY:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dv9 BETA-PHOSPHOGLUCOMUT
ASE

(Bacteroides
vulgatus) 		PF13419
(HAD_2) 		4 MET A  27
PHE A  25
PHE A 147
PHE A 143
 None
 1.25A 3ko0F-3dv9A:
undetectable
3ko0G-3dv9A:
undetectable		 3ko0F-3dv9A:
16.94
3ko0G-3dv9A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2

(Mus musculus) 		PF08447
(PAS_3) 		4 PHE A 228
PHE A 225
PHE A 213
PHE A 191
 None
 1.49A 3ko0F-3gdiA:
undetectable
3ko0G-3gdiA:
undetectable		 3ko0F-3gdiA:
14.53
3ko0G-3gdiA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnm PUTATIVE CHITOBIASE

(Bacteroides
thetaiotaomicron) 		PF00754
(F5_F8_type_C) 		4 PHE A  67
PHE A  69
PHE A  82
PHE A  80
 None
 1.49A 3ko0F-3hnmA:
undetectable
3ko0G-3hnmA:
undetectable		 3ko0F-3hnmA:
16.86
3ko0G-3hnmA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0y PUTATIVE TOXIN
RELATED PROTEIN

(Parabacteroides
distasonis) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 MET A 137
PHE A 148
PHE A 176
PHE A 195
 None
 1.38A 3ko0F-3k0yA:
undetectable
3ko0G-3k0yA:
undetectable		 3ko0F-3k0yA:
15.95
3ko0G-3k0yA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjy HYPOTHETICAL SIGNAL
PEPTIDE PROTEIN

(Sinorhizobium
meliloti) 		PF02643
(DUF192) 		4 MET A  87
PHE A  78
PHE A  80
PHE A 101
 None
 1.32A 3ko0F-3pjyA:
undetectable
3ko0G-3pjyA:
undetectable		 3ko0F-3pjyA:
18.84
3ko0G-3pjyA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q31 CARBONIC ANHYDRASE

(Aspergillus
oryzae) 		PF00194
(Carb_anhydrase) 		4 PHE A 122
PHE A 124
PHE A 157
PHE A 159
 None
 1.33A 3ko0F-3q31A:
undetectable
3ko0G-3q31A:
undetectable		 3ko0F-3q31A:
16.80
3ko0G-3q31A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q31 CARBONIC ANHYDRASE

(Aspergillus
oryzae) 		PF00194
(Carb_anhydrase) 		4 PHE A 157
PHE A 159
PHE A 122
PHE A 124
 None
 1.35A 3ko0F-3q31A:
undetectable
3ko0G-3q31A:
undetectable		 3ko0F-3q31A:
16.80
3ko0G-3q31A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio cholerae) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 MET A 107
PHE A 142
PHE A 284
PHE A 281
 None
 1.25A 3ko0F-3t1bA:
undetectable
3ko0G-3t1bA:
undetectable		 3ko0F-3t1bA:
18.71
3ko0G-3t1bA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga7 LEUKOCYTE ELASTASE
INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		4 PHE A  33
PHE A  70
PHE A  11
PHE A  60
 None
 1.45A 3ko0F-4ga7A:
undetectable
3ko0G-4ga7A:
undetectable		 3ko0F-4ga7A:
14.47
3ko0G-4ga7A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4q BEL-BETA TREFOIL

(Boletus edulis) 		no annotation 4 PHE A  47
PHE A  13
PHE A  95
PHE A  97
 None
 1.31A 3ko0F-4i4qA:
undetectable
3ko0G-4i4qA:
undetectable		 3ko0F-4i4qA:
19.44
3ko0G-4i4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4q BEL-BETA TREFOIL

(Boletus edulis) 		no annotation 4 PHE A  95
PHE A  97
PHE A  47
PHE A  13
 None
 1.41A 3ko0F-4i4qA:
undetectable
3ko0G-4i4qA:
undetectable		 3ko0F-4i4qA:
19.44
3ko0G-4i4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4s BEL BETA-TREFOIL

(Boletus edulis) 		no annotation 4 PHE A  47
PHE A  13
PHE A  95
PHE A  97
 None
 1.32A 3ko0F-4i4sA:
undetectable
3ko0G-4i4sA:
undetectable		 3ko0F-4i4sA:
22.30
3ko0G-4i4sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4s BEL BETA-TREFOIL

(Boletus edulis) 		no annotation 4 PHE A  95
PHE A  97
PHE A  47
PHE A  13
 None
 1.42A 3ko0F-4i4sA:
undetectable
3ko0G-4i4sA:
undetectable		 3ko0F-4i4sA:
22.30
3ko0G-4i4sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 PHE A 404
PHE A 408
PHE A 492
PHE A 489
 None
 1.48A 3ko0F-4pj6A:
undetectable
3ko0G-4pj6A:
undetectable		 3ko0F-4pj6A:
8.08
3ko0G-4pj6A:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqk LECTIN 2

(Agrocybe
aegerita) 		PF13517
(VCBS) 		4 PHE A 217
PHE A 191
PHE A 232
PHE A 176
 None
 1.26A 3ko0F-4tqkA:
undetectable
3ko0G-4tqkA:
undetectable		 3ko0F-4tqkA:
11.79
3ko0G-4tqkA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		4 PHE A  65
PHE A  54
PHE A 347
PHE A 344
 None
 1.24A 3ko0F-4zzeA:
undetectable
3ko0G-4zzeA:
undetectable		 3ko0F-4zzeA:
13.74
3ko0G-4zzeA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		4 PHE A 347
PHE A 344
PHE A  65
PHE A  54
 None
 1.15A 3ko0F-4zzeA:
undetectable
3ko0G-4zzeA:
undetectable		 3ko0F-4zzeA:
13.74
3ko0G-4zzeA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN

([Candida]
glabrata) 		PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central) 		4 PHE A1316
PHE A1312
PHE A1360
PHE A1371
 None
 1.40A 3ko0F-5d0fA:
undetectable
3ko0G-5d0fA:
2.3		 3ko0F-5d0fA:
5.62
3ko0G-5d0fA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5day NAP1-RELATED PROTEIN
1

(Arabidopsis
thaliana) 		PF00956
(NAP) 		4 PHE A 103
PHE A 127
PHE A 132
PHE A 133
 None
 1.46A 3ko0F-5dayA:
undetectable
3ko0G-5dayA:
undetectable		 3ko0F-5dayA:
18.41
3ko0G-5dayA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE

(Homo sapiens) 		PF00632
(HECT) 		4 MET A 832
PHE A 577
PHE A 584
PHE A 823
 None
 1.28A 3ko0F-5hpkA:
undetectable
3ko0G-5hpkA:
undetectable		 3ko0F-5hpkA:
15.14
3ko0G-5hpkA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy5 TRYPTOPHAN
6-HALOGENASE

(Streptomyces
toxytricini) 		PF04820
(Trp_halogenase) 		4 MET A 466
PHE A  94
PHE A 122
PHE A 127
 None
 1.44A 3ko0F-5hy5A:
0.0
3ko0G-5hy5A:
0.0		 3ko0F-5hy5A:
12.16
3ko0G-5hy5A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lv9 THERMOPHILIC
TRYPTOPHAN
HALOGENASE

(Streptomyces
violaceusniger) 		PF04820
(Trp_halogenase) 		4 MET A 462
PHE A  90
PHE A 118
PHE A 123
 None
 1.43A 3ko0F-5lv9A:
0.2
3ko0G-5lv9A:
0.0		 3ko0F-5lv9A:
11.99
3ko0G-5lv9A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4w CULLIN-2

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 MET A 539
PHE A 543
PHE A 490
PHE A 507
 None
 1.40A 3ko0F-5n4wA:
0.9
3ko0G-5n4wA:
0.9		 3ko0F-5n4wA:
10.48
3ko0G-5n4wA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5och -

(-) 		no annotation 4 PHE B 140
PHE B 446
PHE B 266
PHE B 262
 None
 1.34A 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable		 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5och -

(-) 		no annotation 4 PHE B 266
PHE B 262
PHE B 140
PHE B 446
 None
 1.40A 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable		 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swi SUGAR HYDROLASE

(Streptococcus
pneumoniae) 		no annotation 4 PHE B 301
PHE B 332
PHE B 317
PHE B 314
 None
 1.08A 3ko0F-5swiB:
undetectable
3ko0G-5swiB:
0.0		 3ko0F-5swiB:
10.84
3ko0G-5swiB:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swi SUGAR HYDROLASE

(Streptococcus
pneumoniae) 		no annotation 4 PHE B 317
PHE B 314
PHE B 301
PHE B 332
 None
 1.02A 3ko0F-5swiB:
undetectable
3ko0G-5swiB:
0.0		 3ko0F-5swiB:
10.84
3ko0G-5swiB:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr1 CHLORIDE CHANNEL
PROTEIN

(Bos taurus) 		PF00654
(Voltage_CLC) 		4 MET A 412
PHE A 162
PHE A 432
PHE A 405
 None
 1.35A 3ko0F-5tr1A:
undetectable
3ko0G-5tr1A:
undetectable		 3ko0F-5tr1A:
9.94
3ko0G-5tr1A:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd3 CYTOSOLIC PURINE
5'-NUCLEOTIDASE

(Homo sapiens) 		no annotation 4 MET A  53
PHE A  51
PHE A 283
PHE A 264
 None
 1.22A 3ko0F-6dd3A:
undetectable
3ko0G-6dd3A:
undetectable		 3ko0F-6dd3A:
19.54
3ko0G-6dd3A:
19.54