SIMILAR PATTERNS OF AMINO ACIDS FOR 3KO0_B_TFPB201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aoh | CELLULOSOMAL-SCAFFOLDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 4 | ILE A 23PHE A 27PHE A 82PHE A 40 | None | 1.03A | 3ko0B-1aohA:undetectable3ko0J-1aohA:undetectable | 3ko0B-1aohA:19.213ko0J-1aohA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1att | ANTITHROMBIN III (Bos taurus) |
PF00079(Serpin) | 4 | ILE A 389PHE A 124PHE A 107PHE A 109 | None | 1.04A | 3ko0B-1attA:0.33ko0J-1attA:0.3 | 3ko0B-1attA:11.813ko0J-1attA:11.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1att | ANTITHROMBIN III (Bos taurus) |
PF00079(Serpin) | 4 | ILE A 421PHE A 107PHE A 109PHE A 124 | None | 1.03A | 3ko0B-1attA:0.33ko0J-1attA:0.3 | 3ko0B-1attA:11.813ko0J-1attA:11.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1au8 | CATHEPSIN G (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY A 184ILE A 16PHE A 45PHE A 228 | None | 1.05A | 3ko0B-1au8A:undetectable3ko0J-1au8A:undetectable | 3ko0B-1au8A:15.313ko0J-1au8A:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8b | SPORE PROTEASE (Bacillusmegaterium) |
PF03418(Peptidase_A25) | 4 | GLY A 620ILE A 742MET A 745PHE A 496 | None | 0.92A | 3ko0B-1c8bA:undetectable3ko0J-1c8bA:undetectable | 3ko0B-1c8bA:13.753ko0J-1c8bA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbi | AK.1 SERINE PROTEASE (Bacillus sp.Ak1) |
PF00082(Peptidase_S8) | 4 | GLY A 183ILE A 210MET A 222PHE A 194 | None | 0.69A | 3ko0B-1dbiA:undetectable3ko0J-1dbiA:undetectable | 3ko0B-1dbiA:15.023ko0J-1dbiA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecg | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Escherichiacoli) |
PF00156(Pribosyltran)PF13522(GATase_6) | 4 | ILE A 407CYH A 252PHE A 456PHE A 461 | None | 0.93A | 3ko0B-1ecgA:0.03ko0J-1ecgA:0.0 | 3ko0B-1ecgA:15.003ko0J-1ecgA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ehy | PROTEIN (SOLUBLEEPOXIDE HYDROLASE) (Agrobacteriumtumefaciens) |
PF00561(Abhydrolase_1) | 4 | GLY A 37ILE A 219PHE A 155PHE A 179 | None | 1.03A | 3ko0B-1ehyA:0.33ko0J-1ehyA:0.2 | 3ko0B-1ehyA:15.523ko0J-1ehyA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5x | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Thermotogamaritima) |
PF01380(SIS) | 4 | ILE A 155MET A 154PHE A 19PHE A 22 | None | 0.93A | 3ko0B-1j5xA:undetectable3ko0J-1j5xA:undetectable | 3ko0B-1j5xA:15.983ko0J-1j5xA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | GLY A2825PHE A2636PHE A2600PHE A2647 | None | 0.99A | 3ko0B-1js8A:undetectable3ko0J-1js8A:undetectable | 3ko0B-1js8A:13.473ko0J-1js8A:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lvg | GUANYLATE KINASE (Mus musculus) |
PF00625(Guanylate_kin) | 4 | GLY A 106CYH A 98PHE A 32PHE A 25 | 5GP A1202 (-3.2A)NoneNoneNone | 1.05A | 3ko0B-1lvgA:0.03ko0J-1lvgA:0.0 | 3ko0B-1lvgA:20.833ko0J-1lvgA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oru | YUAD PROTEIN (Bacillussubtilis) |
no annotation | 4 | GLY A 99ILE A 160PHE A 30PHE A 114 | None | 0.88A | 3ko0B-1oruA:0.03ko0J-1oruA:0.0 | 3ko0B-1oruA:19.583ko0J-1oruA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q32 | TYROSYL-DNAPHOSPHODIESTERASE (Saccharomycescerevisiae) |
PF06087(Tyr-DNA_phospho) | 4 | GLY A 110ILE A 103CYH A 216PHE A 204 | None | 1.05A | 3ko0B-1q32A:undetectable3ko0J-1q32A:undetectable | 3ko0B-1q32A:12.473ko0J-1q32A:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 4 | GLY A 95ILE A 282PHE A 422PHE A 425 | HEA A 601 ( 4.0A)HEA A 602 ( 4.7A)NoneNone | 1.03A | 3ko0B-1qleA:undetectable3ko0J-1qleA:undetectable | 3ko0B-1qleA:10.653ko0J-1qleA:10.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6n | PROBABLEATP-DEPENDENT RNAHELICASE (Homo sapiens) |
PF00270(DEAD) | 4 | GLY A 46ILE A 80PHE A 99PHE A 227 | None | 0.99A | 3ko0B-1t6nA:undetectable3ko0J-1t6nA:0.0 | 3ko0B-1t6nA:18.183ko0J-1t6nA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t70 | PHOSPHATASE (Deinococcusradiodurans) |
PF13277(YmdB) | 4 | GLY A 187ILE A 170PHE A 31PHE A 239 | None | 1.05A | 3ko0B-1t70A:undetectable3ko0J-1t70A:undetectable | 3ko0B-1t70A:15.943ko0J-1t70A:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5l | PRION PROTEIN (Trachemysscripta) |
PF00377(Prion) | 4 | GLY A 123ILE A 210MET A 213CYH A 214 | None | 0.77A | 3ko0B-1u5lA:undetectable3ko0J-1u5lA:0.4 | 3ko0B-1u5lA:18.753ko0J-1u5lA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5l | PRION PROTEIN (Trachemysscripta) |
PF00377(Prion) | 4 | GLY A 124ILE A 210MET A 213CYH A 214 | None | 0.85A | 3ko0B-1u5lA:undetectable3ko0J-1u5lA:0.4 | 3ko0B-1u5lA:18.753ko0J-1u5lA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | ILE A 255PHE A 81PHE A 287PHE A 282 | None | 0.89A | 3ko0B-1vmaA:2.53ko0J-1vmaA:2.6 | 3ko0B-1vmaA:14.053ko0J-1vmaA:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z45 | GAL10 BIFUNCTIONALPROTEIN (Saccharomycescerevisiae) |
PF01263(Aldose_epim)PF16363(GDP_Man_Dehyd) | 4 | GLY A 424ILE A 694PHE A 540PHE A 662 | None | 0.91A | 3ko0B-1z45A:undetectable3ko0J-1z45A:undetectable | 3ko0B-1z45A:9.593ko0J-1z45A:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ae8 | IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (Staphylococcusaureus) |
PF00475(IGPD) | 4 | GLY A 73ILE A 51PHE A 127PHE A 135 | None | 0.84A | 3ko0B-2ae8A:undetectable3ko0J-2ae8A:1.4 | 3ko0B-2ae8A:14.683ko0J-2ae8A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 4 | GLY A 32ILE A 110PHE A 132PHE A 130 | None | 1.04A | 3ko0B-2afbA:undetectable3ko0J-2afbA:0.0 | 3ko0B-2afbA:16.993ko0J-2afbA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | GLY I 339PHE I 123PHE I 106PHE I 108 | None | 0.93A | 3ko0B-2b4xI:undetectable3ko0J-2b4xI:0.0 | 3ko0B-2b4xI:15.123ko0J-2b4xI:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | ILE I 420PHE I 106PHE I 108PHE I 123 | None | 0.88A | 3ko0B-2b4xI:undetectable3ko0J-2b4xI:0.0 | 3ko0B-2b4xI:15.123ko0J-2b4xI:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bfw | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1) | 4 | GLY A 308ILE A 288MET A 253PHE A 331 | None | 0.95A | 3ko0B-2bfwA:undetectable3ko0J-2bfwA:undetectable | 3ko0B-2bfwA:19.003ko0J-2bfwA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bgs | ALDOSE REDUCTASE (Hordeum vulgare) |
PF00248(Aldo_ket_red) | 4 | GLY A 146ILE A 89PHE A 301PHE A 142 | None | 1.01A | 3ko0B-2bgsA:undetectable3ko0J-2bgsA:undetectable | 3ko0B-2bgsA:14.503ko0J-2bgsA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ccl | CELLULOSOMALSCAFFOLDING PROTEINA (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 4 | ILE A 23PHE A 27PHE A 82PHE A 40 | None | 0.95A | 3ko0B-2cclA:undetectable3ko0J-2cclA:undetectable | 3ko0B-2cclA:20.133ko0J-2cclA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h57 | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN6 (Homo sapiens) |
PF00025(Arf) | 4 | GLY A 167ILE A 34CYH A 22PHE A 92 | None | 1.01A | 3ko0B-2h57A:0.03ko0J-2h57A:undetectable | 3ko0B-2h57A:18.653ko0J-2h57A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hne | L-FUCONATEDEHYDRATASE (Xanthomonascampestris) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 356ILE A 419PHE A 429PHE A 14 | None | 1.04A | 3ko0B-2hneA:undetectable3ko0J-2hneA:undetectable | 3ko0B-2hneA:13.633ko0J-2hneA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jok | PUTATIVEG-NUCLEOTIDEEXCHANGE FACTOR (Burkholderiapseudomallei) |
PF07487(SopE_GEF) | 4 | GLY A 171MET A 132CYH A 131PHE A 130 | None | 0.96A | 3ko0B-2jokA:0.03ko0J-2jokA:undetectable | 3ko0B-2jokA:17.203ko0J-2jokA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5r | GLUTAMYL-TRNASYNTHETASE 1 (Thermotogamaritima) |
PF00749(tRNA-synt_1c) | 4 | ILE A 330PHE A 379PHE A 371PHE A 341 | None | 0.88A | 3ko0B-2o5rA:undetectable3ko0J-2o5rA:undetectable | 3ko0B-2o5rA:12.333ko0J-2o5rA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5r | GLUTAMYL-TRNASYNTHETASE 1 (Thermotogamaritima) |
PF00749(tRNA-synt_1c) | 4 | PHE A 378PHE A 379PHE A 371PHE A 341 | None | 1.03A | 3ko0B-2o5rA:undetectable3ko0J-2o5rA:undetectable | 3ko0B-2o5rA:12.333ko0J-2o5rA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfk | 6-PHOSPHOFRUCTOKINASE ISOZYME I (Escherichiacoli) |
PF00365(PFK) | 4 | GLY A 101ILE A 296PHE A 117PHE A 76 | None | 0.95A | 3ko0B-2pfkA:undetectable3ko0J-2pfkA:undetectable | 3ko0B-2pfkA:14.203ko0J-2pfkA:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy0 | ENDO-BETA-1,3-GLUCANASE (Pyrococcusfuriosus) |
PF00722(Glyco_hydro_16) | 4 | GLY A 190ILE A 228PHE A 131PHE A 258 | None | 1.05A | 3ko0B-2vy0A:undetectable3ko0J-2vy0A:undetectable | 3ko0B-2vy0A:17.323ko0J-2vy0A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnw | ACTIVATED BYTRANSCRIPTION FACTORSSRB (Salmonellaenterica) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 4 | GLY A 47ILE A 370PHE A 71PHE A 76 | None | 0.93A | 3ko0B-2wnwA:undetectable3ko0J-2wnwA:undetectable | 3ko0B-2wnwA:12.093ko0J-2wnwA:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xty | QNRB1 (Klebsiellapneumoniae) |
PF00805(Pentapeptide)PF13599(Pentapeptide_4) | 4 | GLY A 93ILE A 116PHE A 171PHE A 164 | None | 0.97A | 3ko0B-2xtyA:undetectable3ko0J-2xtyA:undetectable | 3ko0B-2xtyA:21.213ko0J-2xtyA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zf5 | GLYCEROL KINASE (Thermococcuskodakarensis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | GLY O 365ILE O 316PHE O 341PHE O 337 | None | 1.04A | 3ko0B-2zf5O:undetectable3ko0J-2zf5O:undetectable | 3ko0B-2zf5O:11.903ko0J-2zf5O:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7x | FK506-BINDINGPROTEIN 6 (Homo sapiens) |
PF00254(FKBP_C) | 4 | GLY A 105ILE A 43PHE A 135PHE A 112 | None | 1.03A | 3ko0B-3b7xA:undetectable3ko0J-3b7xA:undetectable | 3ko0B-3b7xA:20.533ko0J-3b7xA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cj1 | ECTONUCLEOSIDETRIPHOSPHATEDIPHOSPHOHYDROLASE 2 (Rattusnorvegicus) |
PF01150(GDA1_CD39) | 5 | GLY A 203ILE A 209PHE A 420PHE A 348PHE A 425 | None | 1.43A | 3ko0B-3cj1A:0.73ko0J-3cj1A:undetectable | 3ko0B-3cj1A:11.673ko0J-3cj1A:11.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euw | MYO-INOSITOLDEHYDROGENASE (Corynebacteriumglutamicum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 111ILE A 96CYH A 92PHE A 291 | None | 1.00A | 3ko0B-3euwA:undetectable3ko0J-3euwA:undetectable | 3ko0B-3euwA:11.923ko0J-3euwA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1w | MANNOSE-6-PHOSPHATEISOMERASE (Salmonellaenterica) |
PF01238(PMI_typeI) | 4 | ILE A 335PHE A 344PHE A 85PHE A 323 | None | 0.80A | 3ko0B-3h1wA:undetectable3ko0J-3h1wA:undetectable | 3ko0B-3h1wA:12.283ko0J-3h1wA:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn5 | PUTATIVE EXPORTEDPROTEIN BF0290 (Bacteroidesfragilis) |
PF12866(DUF3823) | 4 | GLY A 149ILE A 227CYH A 217PHE A 192 | None | 0.84A | 3ko0B-3hn5A:undetectable3ko0J-3hn5A:undetectable | 3ko0B-3hn5A:12.963ko0J-3hn5A:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3im0 | VAL-1 (ParameciumbursariaChlorella virusCVK2) |
no annotation | 4 | ILE A 117PHE A 61PHE A 235PHE A 59 | None | 0.97A | 3ko0B-3im0A:undetectable3ko0J-3im0A:undetectable | 3ko0B-3im0A:17.363ko0J-3im0A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | GLY A 227ILE A 254MET A 273PHE A 238 | None | 0.76A | 3ko0B-3lpdA:undetectable3ko0J-3lpdA:undetectable | 3ko0B-3lpdA:12.683ko0J-3lpdA:12.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mmp | ELONGATION FACTOR TU2, ELONGATION FACTORTS (Escherichiacoli) |
PF00009(GTP_EFTU)PF00889(EF_TS)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | GLY A1384ILE A1341PHE A1374PHE A1332 | None | 0.94A | 3ko0B-3mmpA:undetectable3ko0J-3mmpA:undetectable | 3ko0B-3mmpA:9.193ko0J-3mmpA:9.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nix | FLAVOPROTEIN/DEHYDROGENASE (Cytophagahutchinsonii) |
PF01494(FAD_binding_3) | 4 | GLY A 358ILE A 303PHE A 231PHE A 238 | None | 0.87A | 3ko0B-3nixA:undetectable3ko0J-3nixA:undetectable | 3ko0B-3nixA:14.323ko0J-3nixA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nom | GLUTAMINECYCLOTRANSFERASE (Zymomonasmobilis) |
PF05096(Glu_cyclase_2) | 4 | GLY A 212ILE A 208PHE A 240PHE A 48 | None | 1.04A | 3ko0B-3nomA:undetectable3ko0J-3nomA:undetectable | 3ko0B-3nomA:16.033ko0J-3nomA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nuz | PUTATIVE ACETYLXYLAN ESTERASE (Bacteroidesfragilis) |
PF12715(Abhydrolase_7) | 4 | GLY A 336ILE A 331PHE A 178PHE A 400 | None | 0.94A | 3ko0B-3nuzA:undetectable3ko0J-3nuzA:undetectable | 3ko0B-3nuzA:14.123ko0J-3nuzA:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opn | PUTATIVE HEMOLYSIN (Lactococcuslactis) |
PF01728(FtsJ) | 4 | GLY A 150ILE A 128PHE A 108PHE A 118 | None | 1.02A | 3ko0B-3opnA:undetectable3ko0J-3opnA:undetectable | 3ko0B-3opnA:16.383ko0J-3opnA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgu | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydomonasreinhardtii) |
PF00155(Aminotran_1_2) | 4 | GLY A 438ILE A 393PHE A 414PHE A 366 | None | 0.96A | 3ko0B-3qguA:undetectable3ko0J-3qguA:undetectable | 3ko0B-3qguA:12.443ko0J-3qguA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT LNADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 4 | GLY L 145PHE L 183PHE L 186PHE M 408 | None | 0.99A | 3ko0B-3rkoL:undetectable3ko0J-3rkoL:undetectable | 3ko0B-3rkoL:8.963ko0J-3rkoL:8.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rp2 | RAT MAST CELLPROTEASE II (Rattus rattus) |
PF00089(Trypsin) | 4 | GLY A 184ILE A 16PHE A 45PHE A 228 | None | 1.04A | 3ko0B-3rp2A:undetectable3ko0J-3rp2A:undetectable | 3ko0B-3rp2A:21.893ko0J-3rp2A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5v | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 4 | CYH B 65PHE B 68PHE B 90PHE B 16 | None | 0.90A | 3ko0B-3t5vB:undetectable3ko0J-3t5vB:undetectable | 3ko0B-3t5vB:13.083ko0J-3t5vB:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdo | MFS TRANSPORTER (Escherichiacoli) |
PF07690(MFS_1) | 4 | GLY A 69ILE A 327PHE A 144PHE A 21 | None | 0.92A | 3ko0B-3wdoA:undetectable3ko0J-3wdoA:undetectable | 3ko0B-3wdoA:12.923ko0J-3wdoA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxw | ADIPONECTIN RECEPTORPROTEIN 2 (Homo sapiens) |
PF03006(HlyIII) | 4 | GLY A 229ILE A 258PHE A 269PHE A 282 | None | 1.04A | 3ko0B-3wxwA:1.33ko0J-3wxwA:1.4 | 3ko0B-3wxwA:18.223ko0J-3wxwA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9y | ALPHA-GLUCOSIDASE,PUTATIVE, ADG31B (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF17137(DUF5110) | 4 | GLY A 47ILE A 112PHE A 135PHE A 144 | None | 0.82A | 3ko0B-4b9yA:undetectable3ko0J-4b9yA:undetectable | 3ko0B-4b9yA:7.713ko0J-4b9yA:7.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 4 | ILE A 353PHE A 366PHE A 291PHE A 193 | None | 1.04A | 3ko0B-4btpA:1.63ko0J-4btpA:1.5 | 3ko0B-4btpA:9.183ko0J-4btpA:9.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d0o | A-KINASE ANCHORPROTEIN 13 (Homo sapiens) |
PF00621(RhoGEF) | 4 | GLY A2027ILE A2019CYH A2146PHE A2104 | None | 1.04A | 3ko0B-4d0oA:1.03ko0J-4d0oA:0.9 | 3ko0B-4d0oA:19.423ko0J-4d0oA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dw1 | P2X PURINOCEPTOR (Danio rerio) |
PF00864(P2X_receptor) | 4 | GLY A 254PHE A 233PHE A 322PHE A 102 | None | 0.96A | 3ko0B-4dw1A:undetectable3ko0J-4dw1A:undetectable | 3ko0B-4dw1A:13.783ko0J-4dw1A:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4egw | MAGNESIUM TRANSPORTPROTEIN CORA (Methanocaldococcusjannaschii) |
PF01544(CorA) | 4 | GLY A 93ILE A 208PHE A 134PHE A 128 | NoneNoneNoneBU1 A 319 (-3.7A) | 0.90A | 3ko0B-4egwA:undetectable3ko0J-4egwA:undetectable | 3ko0B-4egwA:15.003ko0J-4egwA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euf | PUTATIVE REDUCTASECA_C0462 (Clostridiumacetobutylicum) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 4 | GLY A 329ILE A 317PHE A 135PHE A 214 | None | 0.83A | 3ko0B-4eufA:undetectable3ko0J-4eufA:undetectable | 3ko0B-4eufA:13.463ko0J-4eufA:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fch | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | GLY A 289PHE A 314PHE A 379PHE A 340 | None | 0.96A | 3ko0B-4fchA:undetectable3ko0J-4fchA:undetectable | 3ko0B-4fchA:15.073ko0J-4fchA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fem | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | GLY A 289PHE A 314PHE A 379PHE A 340 | None | 0.95A | 3ko0B-4femA:undetectable3ko0J-4femA:undetectable | 3ko0B-4femA:15.733ko0J-4femA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwt | ELONGATION FACTORTS, ELONGATIONFACTOR TU, LINKER, QBETA REPLICASE (Escherichiacoli;Escherichiavirus Qbeta) |
PF00009(GTP_EFTU)PF00889(EF_TS)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)PF03431(RNA_replicase_B) | 4 | GLY A 669ILE A 626PHE A 659PHE A 617 | None | 0.88A | 3ko0B-4fwtA:undetectable3ko0J-4fwtA:undetectable | 3ko0B-4fwtA:6.153ko0J-4fwtA:6.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga7 | LEUKOCYTE ELASTASEINHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | GLY A 292PHE A 70PHE A 58PHE A 60 | None | 1.01A | 3ko0B-4ga7A:undetectable3ko0J-4ga7A:undetectable | 3ko0B-4ga7A:14.473ko0J-4ga7A:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 12 (Thermusthermophilus) |
PF00361(Proton_antipo_M)PF00662(Proton_antipo_N) | 4 | GLY L 508ILE L 294PHE L 532PHE L 524 | None | 0.85A | 3ko0B-4heaL:0.53ko0J-4heaL:undetectable | 3ko0B-4heaL:10.773ko0J-4heaL:10.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j75 | TRYPTOPHANYL-TRNASYNTHETASE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | ILE A 430CYH A 433PHE A 438PHE A 383 | None | 0.96A | 3ko0B-4j75A:undetectable3ko0J-4j75A:undetectable | 3ko0B-4j75A:14.443ko0J-4j75A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j75 | TRYPTOPHANYL-TRNASYNTHETASE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | ILE A 430PHE A 350PHE A 412PHE A 414 | None | 1.02A | 3ko0B-4j75A:undetectable3ko0J-4j75A:undetectable | 3ko0B-4j75A:14.443ko0J-4j75A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l2k | TANKYRASE-2 (Homo sapiens) |
PF00644(PARP) | 4 | GLY A1058ILE A1039PHE A1098PHE A1061 | None | 1.05A | 3ko0B-4l2kA:undetectable3ko0J-4l2kA:undetectable | 3ko0B-4l2kA:16.753ko0J-4l2kA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhu | 9C2 TCR DELTA CHAIN9C2 TCR GAMMA CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY G 118ILE D 49PHE D 38PHE D 109 | None | 0.86A | 3ko0B-4lhuG:undetectable3ko0J-4lhuG:undetectable | 3ko0B-4lhuG:18.433ko0J-4lhuG:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oa7 | TANKYRASE-1 (Homo sapiens) |
PF00644(PARP) | 4 | GLY A1211ILE A1192PHE A1251PHE A1214 | None2XS A1402 ( 4.7A)NoneNone | 1.03A | 3ko0B-4oa7A:undetectable3ko0J-4oa7A:undetectable | 3ko0B-4oa7A:19.813ko0J-4oa7A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 4 | GLY A 195ILE A 210PHE A 132PHE A 119 | None | 0.71A | 3ko0B-4q22A:undetectable3ko0J-4q22A:undetectable | 3ko0B-4q22A:13.233ko0J-4q22A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6p | CONSERVEDHYPOTHETICALSECRETED PROTEIN (Helicobacterpylori) |
PF17033(Peptidase_M99)PF17129(Peptidase_M99_C)PF17130(Peptidase_M99_m) | 4 | ILE A 433PHE A 386PHE A 406PHE A 437 | None | 0.97A | 3ko0B-4q6pA:undetectable3ko0J-4q6pA:undetectable | 3ko0B-4q6pA:13.563ko0J-4q6pA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6t | GLYCOSYL HYDROLASE,FAMILY 18 (Pseudomonasprotegens) |
PF00704(Glyco_hydro_18) | 4 | GLY A 259ILE A 178PHE A 148PHE A 159 | None | 1.00A | 3ko0B-4q6tA:undetectable3ko0J-4q6tA:undetectable | 3ko0B-4q6tA:13.243ko0J-4q6tA:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2b | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Ochrobactrumanthropi) |
PF01547(SBP_bac_1) | 4 | GLY A 225ILE A 392PHE A 400PHE A 233 | None | 0.80A | 3ko0B-4r2bA:0.43ko0J-4r2bA:0.4 | 3ko0B-4r2bA:15.683ko0J-4r2bA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rs1 | GRANULOCYTE-MACROPHAGECOLONY-STIMULATINGFACTOR RECEPTORSUBUNIT ALPHA (Homo sapiens) |
PF09240(IL6Ra-bind) | 4 | GLY B 158ILE B 135PHE B 105PHE B 187 | None | 0.67A | 3ko0B-4rs1B:undetectable3ko0J-4rs1B:undetectable | 3ko0B-4rs1B:18.623ko0J-4rs1B:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tlh | ETHANOLAMINEUTILIZATION PROTEINEUTL (Clostridiumperfringens) |
PF00936(BMC) | 4 | GLY A 71ILE A 6PHE A 203PHE A 184 | None | 0.81A | 3ko0B-4tlhA:undetectable3ko0J-4tlhA:undetectable | 3ko0B-4tlhA:17.543ko0J-4tlhA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8y | CRISPR SYSTEM CMRSUBUNIT CMR2 (Pyrococcusfuriosus) |
PF12469(DUF3692) | 4 | GLY A 847ILE A 807PHE A 791PHE A 858 | None | 1.03A | 3ko0B-4w8yA:1.03ko0J-4w8yA:undetectable | 3ko0B-4w8yA:9.053ko0J-4w8yA:9.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 4 | GLY A 222ILE A 120PHE A 177PHE A 154 | None | 1.00A | 3ko0B-4wxjA:undetectable3ko0J-4wxjA:undetectable | 3ko0B-4wxjA:18.463ko0J-4wxjA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xdq | GLYCOSIDE HYDROLASEFAMILY PROTEIN (Mycolicibacteriumthermoresistibile) |
PF00722(Glyco_hydro_16) | 4 | GLY A 192PHE A 147PHE A 195PHE A 206 | None | 0.93A | 3ko0B-4xdqA:undetectable3ko0J-4xdqA:undetectable | 3ko0B-4xdqA:14.873ko0J-4xdqA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | BAND 3 ANIONTRANSPORT PROTEIN (Homo sapiens) |
PF00955(HCO3_cotransp) | 4 | GLY A 714ILE A 487PHE A 478PHE A 471 | None | 0.76A | 3ko0B-4yzfA:undetectable3ko0J-4yzfA:undetectable | 3ko0B-4yzfA:8.353ko0J-4yzfA:8.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwn | MONOGLYCERIDE LIPASE (Saccharomycescerevisiae) |
PF12146(Hydrolase_4) | 4 | GLY A 258ILE A 233CYH A 134PHE A 96 | None | 0.97A | 3ko0B-4zwnA:undetectable3ko0J-4zwnA:undetectable | 3ko0B-4zwnA:14.983ko0J-4zwnA:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dud | YBGJYBGK (Escherichiacoli) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | GLY A 253ILE B 9CYH A 260PHE A 193 | None | 0.75A | 3ko0B-5dudA:undetectable3ko0J-5dudA:undetectable | 3ko0B-5dudA:16.393ko0J-5dudA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dud | YBGJYBGK (Escherichiacoli) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | GLY A 254ILE B 9CYH A 260PHE A 193 | None | 1.02A | 3ko0B-5dudA:undetectable3ko0J-5dudA:undetectable | 3ko0B-5dudA:16.393ko0J-5dudA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ei0 | SERPIN A12 (Homo sapiens) |
PF00079(Serpin) | 4 | GLY A 327PHE A 116PHE A 102PHE A 104 | None | 0.91A | 3ko0B-5ei0A:undetectable3ko0J-5ei0A:undetectable | 3ko0B-5ei0A:13.453ko0J-5ei0A:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5r | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF13589(HATPase_c_3) | 4 | GLY A 162ILE A 241PHE A 209PHE A 205 | ANP A 300 ( 4.5A)NoneNoneNone | 0.87A | 3ko0B-5f5rA:undetectable3ko0J-5f5rA:undetectable | 3ko0B-5f5rA:18.223ko0J-5f5rA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 4 | GLY B 740ILE B 754PHE B 670PHE B 657 | None | 0.83A | 3ko0B-5gztB:undetectable3ko0J-5gztB:undetectable | 3ko0B-5gztB:6.273ko0J-5gztB:6.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 4 | GLY A 740ILE A 754PHE A 670PHE A 657 | None | 0.81A | 3ko0B-5gzuA:undetectable3ko0J-5gzuA:undetectable | 3ko0B-5gzuA:7.233ko0J-5gzuA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h29 | THIOREDOXINREDUCTASE/GLUTATHIONE-RELATED PROTEIN (Enterococcusfaecalis) |
no annotation | 4 | GLY A 445ILE A 441PHE A 367PHE A 397 | None | 1.06A | 3ko0B-5h29A:undetectable3ko0J-5h29A:undetectable | 3ko0B-5h29A:22.123ko0J-5h29A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hph | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF00183(HSP90)PF13589(HATPase_c_3) | 4 | GLY A 162ILE A 241PHE A 209PHE A 205 | ANP A 801 ( 4.3A)NoneNoneNone | 0.97A | 3ko0B-5hphA:undetectable3ko0J-5hphA:undetectable | 3ko0B-5hphA:11.243ko0J-5hphA:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1d | PHOSPHATE BINDINGPROTEIN (Stenotrophomonasmaltophilia) |
PF12849(PBP_like_2) | 4 | ILE A 140PHE A 192PHE A 121PHE A 188 | None | 0.98A | 3ko0B-5j1dA:undetectable3ko0J-5j1dA:undetectable | 3ko0B-5j1dA:14.483ko0J-5j1dA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | GLY A 678ILE A 567PHE A 564PHE A 656 | None | 0.91A | 3ko0B-5l46A:undetectable3ko0J-5l46A:undetectable | 3ko0B-5l46A:9.003ko0J-5l46A:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ELECTRON TRANSFERFLAVOPROTEIN LARGESUBUNITELECTRON TRANSFERFLAVOPROTEIN SMALLSUBUNIT (Clostridioidesdifficile) |
no annotation | 4 | GLY B 253ILE A 270CYH A 272PHE A 302 | None | 0.88A | 3ko0B-5ol2B:undetectable3ko0J-5ol2B:undetectable | 3ko0B-5ol2B:18.603ko0J-5ol2B:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oup | PERFORIN-LIKEPROTEIN 1 (Toxoplasmagondii) |
no annotation | 4 | GLY A 478ILE A 737PHE A 670PHE A 767 | None | 0.92A | 3ko0B-5oupA:undetectable3ko0J-5oupA:undetectable | 3ko0B-5oupA:14.853ko0J-5oupA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swi | SUGAR HYDROLASE (Streptococcuspneumoniae) |
no annotation | 4 | GLY B 298PHE B 314PHE B 301PHE B 332 | None | 0.95A | 3ko0B-5swiB:undetectable3ko0J-5swiB:undetectable | 3ko0B-5swiB:10.843ko0J-5swiB:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ta1 | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) |
no annotation | 4 | GLY A 193CYH A 243PHE A 264PHE A 274 | None | 0.97A | 3ko0B-5ta1A:undetectable3ko0J-5ta1A:undetectable | 3ko0B-5ta1A:9.093ko0J-5ta1A:9.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6acd | - (-) |
no annotation | 4 | GLY A1026PHE A 782PHE A 784PHE A1034 | None | 1.02A | 3ko0B-6acdA:1.23ko0J-6acdA:1.2 | 3ko0B-6acdA:undetectable3ko0J-6acdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3x | CLEAVAGE STIMULATIONFACTOR SUBUNIT 1 (Homo sapiens) |
no annotation | 4 | GLY A 120ILE A 166PHE A 200PHE A 181 | None | 0.87A | 3ko0B-6b3xA:undetectable3ko0J-6b3xA:undetectable | 3ko0B-6b3xA:14.373ko0J-6b3xA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c5x | SUPPRESSOR OFCYTOKINE SIGNALLING1 (Xenopus laevis) |
no annotation | 4 | GLY D 99PHE D 209PHE D 207PHE D 79 | None | 0.73A | 3ko0B-6c5xD:undetectable3ko0J-6c5xD:undetectable | 3ko0B-6c5xD:21.783ko0J-6c5xD:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxh | PARTICULATE METHANEMONOOXYGENASE, ASUBUNITPARTICULATE METHANEMONOOXYGENASE, BSUBUNIT (Methylomicrobiumalcaliphilum) |
no annotation | 4 | GLY B 185ILE A 91MET A 141PHE A 88 | None | 0.82A | 3ko0B-6cxhB:undetectable3ko0J-6cxhB:1.1 | 3ko0B-6cxhB:20.753ko0J-6cxhB:20.75 |