SIMILAR PATTERNS OF AMINO ACIDS FOR 3KMO_A_EAAA214_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5c RAB6 GTPASE

(Plasmodium
falciparum) 		PF00071
(Ras) 		5 VAL A  90
GLY A 123
GLN A  70
ASN A 124
GLY A  23
 None
None
None
GDP  A 201 (-3.3A)
GDP  A 201 (-3.4A)
 1.33A 3kmoA-1d5cA:
0.0		 3kmoA-1d5cA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e7n BETA-CRYSTALLIN B2

(Mus musculus) 		PF00030
(Crystall) 		5 TYR A  62
VAL A  37
GLY A  60
VAL A  43
GLN A  54
 None
 1.28A 3kmoA-1e7nA:
undetectable		 3kmoA-1e7nA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebd DIHYDROLIPOAMIDE
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 TYR A 138
VAL A 129
VAL A  15
ASN A 131
GLY A 117
 None
 1.30A 3kmoA-1ebdA:
0.0		 3kmoA-1ebdA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek0 PROTEIN (GTP-BINDING
PROTEIN YPT51)

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		5 VAL A  86
GLY A 119
GLN A  66
ASN A 120
GLY A  19
 None
None
GNP  A 501 ( 4.9A)
GNP  A 501 (-3.2A)
GNP  A 501 (-3.3A)
 1.43A 3kmoA-1ek0A:
undetectable		 3kmoA-1ek0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gam GAMMA B CRYSTALLIN

(Bos taurus) 		PF00030
(Crystall) 		5 TYR A 151
VAL A 126
GLY A 149
VAL A 132
GLN A 143
 None
 1.32A 3kmoA-1gamA:
undetectable		 3kmoA-1gamA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gk2 HISTIDINE
AMMONIA-LYASE

(Pseudomonas
putida) 		PF00221
(Lyase_aromatic) 		5 PHE A 370
VAL A 372
GLY A 375
ASN A 378
GLY A 380
 None
 1.20A 3kmoA-1gk2A:
0.0		 3kmoA-1gk2A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1huq RAB5C

(Mus musculus) 		PF00071
(Ras) 		5 VAL A 100
GLY A 133
GLN A  80
ASN A 134
GLY A  33
 None
None
None
GNP  A 200 (-3.3A)
GNP  A 200 (-3.4A)
 1.42A 3kmoA-1huqA:
0.0		 3kmoA-1huqA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcl CYCLODEXTRIN
GLYCOSYLTRANSFERASE

(Bacillus
circulans) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		5 TYR A 456
VAL A 471
GLY A 454
GLN A 410
GLY A 475
 None
 1.02A 3kmoA-1kclA:
0.0		 3kmoA-1kclA:
15.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		7 TYR A   7
PHE A   8
VAL A  10
GLY A  12
VAL A  35
TRP A  38
GLN A  39
 None
GSH  A 504 (-4.7A)
None
None
None
GSH  A 504 (-3.9A)
None
 0.29A 3kmoA-1lbkA:
35.5		 3kmoA-1lbkA:
96.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m8u GAMMA-E

(Bos taurus) 		PF00030
(Crystall) 		5 TYR A 151
VAL A 126
GLY A 149
VAL A 132
GLN A 143
 None
 1.31A 3kmoA-1m8uA:
undetectable		 3kmoA-1m8uA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mkx PRETHROMBIN-2

(Bos taurus) 		PF00089
(Trypsin)
PF09396
(Thrombin_light) 		5 VAL K 213
GLY K 196
VAL K 158
ASN K 143
GLY K 193
 None
 1.18A 3kmoA-1mkxK:
undetectable		 3kmoA-1mkxK:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odv PHOTOACTIVE YELLOW
PROTEIN

(Halorhodospira
halophila) 		PF00989
(PAS) 		5 GLY A  59
VAL A 120
TRP A 119
ASN A  38
GLY A  37
 None
 1.43A 3kmoA-1odvA:
undetectable		 3kmoA-1odvA:
20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
GLY A  12
ASN A 203
GLY A 204
 None
GSH  A1001 (-4.8A)
None
None
None
 0.38A 3kmoA-1tu7A:
30.3		 3kmoA-1tu7A:
41.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukw ACYL-COA
DEHYDROGENASE

(Thermus
thermophilus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		5 TYR A 115
GLY A 104
VAL A 386
GLN A 390
GLY A 282
 None
 1.19A 3kmoA-1ukwA:
undetectable		 3kmoA-1ukwA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vgw 4-DIPHOSPHOCYTIDYL-2
C-METHYL-D-ERYTHRITO
L SYNTHASE

(Neisseria
gonorrhoeae) 		PF01128
(IspD) 		5 VAL A  54
GLY A  78
VAL A 107
ASN A  88
GLY A  89
 None
 1.18A 3kmoA-1vgwA:
undetectable		 3kmoA-1vgwA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x2b PROLINE
IMINOPEPTIDASE

(Serratia
marcescens) 		PF00561
(Abhydrolase_1) 		5 GLY A  33
TRP A 107
GLN A 106
ASN A  34
GLY A  37
 None
 1.38A 3kmoA-1x2bA:
undetectable		 3kmoA-1x2bA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3s RAS-RELATED PROTEIN
RAB-18

(Homo sapiens) 		PF00071
(Ras) 		5 VAL A  87
GLY A 121
GLN A  67
ASN A 122
GLY A  20
 None
None
None
GNP  A 300 (-3.2A)
GNP  A 300 (-3.3A)
 1.36A 3kmoA-1x3sA:
undetectable		 3kmoA-1x3sA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytq BETA CRYSTALLIN B2

(Homo sapiens) 		PF00030
(Crystall) 		5 TYR A 170
VAL A 145
GLY A 168
VAL A 151
GLN A 162
 None
 1.41A 3kmoA-1ytqA:
undetectable		 3kmoA-1ytqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzn GTP-BINDING PROTEIN
YPT1

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		5 VAL A  87
GLY A 120
GLN A  67
ASN A 121
GLY A  20
 None
None
None
GNP  A 300 (-3.2A)
GNP  A 300 (-3.3A)
 1.39A 3kmoA-1yznA:
undetectable		 3kmoA-1yznA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z06 RAS-RELATED PROTEIN
RAB-33B

(Mus musculus) 		PF00071
(Ras) 		5 VAL A 113
GLY A 147
GLN A  92
ASN A 148
GLY A  45
 None
None
None
GNP  A 204 (-3.3A)
GNP  A 204 (-3.1A)
 1.44A 3kmoA-1z06A:
undetectable		 3kmoA-1z06A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3l AMP DEAMINASE

(Arabidopsis
thaliana) 		PF00962
(A_deaminase) 		5 PHE A 724
VAL A 731
GLY A 701
VAL A 723
GLY A 728
 None
 1.33A 3kmoA-2a3lA:
undetectable		 3kmoA-2a3lA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bov RAS-RELATED PROTEIN
RAL-A

(Homo sapiens) 		PF00071
(Ras) 		5 VAL A  92
GLY A 126
GLN A  72
ASN A 127
GLY A  26
 None
None
None
GDP  A1184 (-3.3A)
GDP  A1184 (-3.2A)
 1.38A 3kmoA-2bovA:
undetectable		 3kmoA-2bovA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dad ABSENT IN MELANOMA 1
PROTEIN

(Homo sapiens) 		PF00030
(Crystall) 		5 TYR A  67
VAL A  42
GLY A  65
VAL A  48
GLN A  59
 None
 1.07A 3kmoA-2dadA:
undetectable		 3kmoA-2dadA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2efe SMALL GTP-BINDING
PROTEIN-LIKE

(Arabidopsis
thaliana) 		PF00071
(Ras) 		5 VAL B  89
GLY B 122
GLN B  69
ASN B 123
GLY B  22
 None
None
None
GNH  B1200 (-3.4A)
GNH  B1200 (-3.2A)
 1.34A 3kmoA-2efeB:
undetectable		 3kmoA-2efeB:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eih ALCOHOL
DEHYDROGENASE

(Thermus
thermophilus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 PHE A 335
VAL A 334
VAL A 181
GLN A 185
GLY A 314
 None
 1.10A 3kmoA-2eihA:
undetectable		 3kmoA-2eihA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fim TUBBY RELATED
PROTEIN 1

(Homo sapiens) 		PF01167
(Tub) 		5 PHE A 329
GLY A 315
GLN A 336
ASN A 331
GLY A 332
 None
 1.41A 3kmoA-2fimA:
undetectable		 3kmoA-2fimA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fli RIBULOSE-PHOSPHATE
3-EPIMERASE

(Streptococcus
pyogenes) 		PF00834
(Ribul_P_3_epim) 		5 PHE A  42
GLY A 143
VAL A  71
ASN A  45
GLY A  40
 None
DX5  A1901 (-3.6A)
None
None
None
 1.27A 3kmoA-2fliA:
undetectable		 3kmoA-2fliA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gh8 CAPSID PROTEIN

(Vesicular
exanthema of
swine virus) 		PF00915
(Calici_coat) 		5 PHE A 659
GLY A 662
VAL A 702
ASN A 601
GLY A 672
 None
 1.25A 3kmoA-2gh8A:
undetectable		 3kmoA-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gh8 CAPSID PROTEIN

(Vesicular
exanthema of
swine virus) 		PF00915
(Calici_coat) 		5 VAL A 671
GLY A 662
VAL A 702
TRP A 658
GLN A 657
 None
 1.34A 3kmoA-2gh8A:
undetectable		 3kmoA-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gop TRILOBED PROTEASE

(Pyrococcus
furiosus) 		PF07676
(PD40) 		5 PHE A 277
VAL A 265
GLY A 264
VAL A 275
ASN A 244
 None
 1.38A 3kmoA-2gopA:
undetectable		 3kmoA-2gopA:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		7 TYR A   7
PHE A   8
VAL A  10
GLY A  12
TRP A  38
ASN A 202
GLY A 203
 GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
None
GTS  A 208 (-3.9A)
None
None
 0.27A 3kmoA-2gsrA:
35.3		 3kmoA-2gsrA:
81.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iut DNA TRANSLOCASE FTSK

(Pseudomonas
aeruginosa) 		PF01580
(FtsK_SpoIIIE) 		5 PHE A 553
VAL A 547
VAL A 557
ASN A 549
GLY A 552
 None
 1.43A 3kmoA-2iutA:
undetectable		 3kmoA-2iutA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qng UNCHARACTERIZED
PROTEIN SAV2460

(Streptomyces
avermitilis) 		PF02342
(TerD) 		5 PHE A 129
VAL A 132
GLY A 134
VAL A 140
GLY A 159
 None
 1.40A 3kmoA-2qngA:
undetectable		 3kmoA-2qngA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qz7 UNCHARACTERIZED
PROTEIN SCO6318

(Streptomyces
coelicolor) 		PF02342
(TerD) 		5 PHE A 142
VAL A 145
GLY A 147
VAL A 153
GLY A 172
 None
 1.39A 3kmoA-2qz7A:
undetectable		 3kmoA-2qz7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z04 PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
ATPASE SUBUNIT

(Aquifex
aeolicus) 		PF02222
(ATP-grasp) 		5 PHE A 234
VAL A 233
GLY A 232
VAL A 236
GLY A 181
 None
 1.35A 3kmoA-2z04A:
undetectable		 3kmoA-2z04A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aat ASPARTATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		6 PHE A 260
VAL A 267
GLY A 268
VAL A  53
TRP A 319
GLY A 302
 None
 1.49A 3kmoA-3aatA:
undetectable		 3kmoA-3aatA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayf NITRIC OXIDE
REDUCTASE

(Geobacillus
stearothermophilus) 		PF00115
(COX1) 		5 TYR A  98
GLY A  85
VAL A  75
GLN A 206
GLY A  80
 None
 1.17A 3kmoA-3ayfA:
undetectable		 3kmoA-3ayfA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6v KINESIN-LIKE PROTEIN
KIF3C

(Homo sapiens) 		PF00225
(Kinesin) 		5 VAL A  85
GLY A 240
VAL A  78
ASN A  90
GLY A  91
 None
 1.25A 3kmoA-3b6vA:
undetectable		 3kmoA-3b6vA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bem PUTATIVE NAD(P)H
NITROREDUCTASE YDFN

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		5 GLY A 158
VAL A  72
GLN A  55
ASN A  66
GLY A  67
 FMN  A 300 (-3.6A)
None
None
None
None
 1.29A 3kmoA-3bemA:
undetectable		 3kmoA-3bemA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bmw CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		5 TYR A 456
VAL A 471
GLY A 454
GLN A 410
GLY A 475
 None
 1.08A 3kmoA-3bmwA:
undetectable		 3kmoA-3bmwA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brn LIPOCALIN

(Argas
monolakensis) 		PF02098
(His_binding) 		5 TYR A  27
VAL A  45
GLY A  26
ASN A  24
GLY A  23
 SRO  A 158 (-3.5A)
None
None
None
None
 1.44A 3kmoA-3brnA:
undetectable		 3kmoA-3brnA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5n TUBBY-RELATED
PROTEIN 1

(Homo sapiens) 		PF01167
(Tub) 		5 PHE A 329
GLY A 315
GLN A 336
ASN A 331
GLY A 332
 None
 1.39A 3kmoA-3c5nA:
undetectable		 3kmoA-3c5nA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5o UPF0311 PROTEIN
RPA1785

(Rhodopseudomonas
palustris) 		PF11578
(DUF3237) 		5 PHE A  11
GLY A  48
VAL A  10
GLN A 151
GLY A  45
 None
 1.39A 3kmoA-3c5oA:
undetectable		 3kmoA-3c5oA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e20 EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Schizosaccharomyces
pombe) 		no annotation 5 VAL C  85
GLY C  39
GLN C 121
ASN C  88
GLY C  89
 None
 1.43A 3kmoA-3e20C:
undetectable		 3kmoA-3e20C:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8p UNCHARACTERIZED
PROTEIN

(Shewanella
oneidensis) 		PF03061
(4HBT) 		5 VAL A 163
GLY A 164
VAL A 141
ASN A 137
GLY A 136
 None
 1.22A 3kmoA-3e8pA:
undetectable		 3kmoA-3e8pA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f5d PROTEIN YDEA

(Bacillus
subtilis) 		PF01965
(DJ-1_PfpI) 		5 VAL A 103
GLY A 101
VAL A 143
ASN A 120
GLY A 119
 None
 1.26A 3kmoA-3f5dA:
undetectable		 3kmoA-3f5dA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ljy PUTATIVE ADHESIN

(Parabacteroides
distasonis) 		PF10988
(DUF2807) 		5 GLY A 199
VAL A 257
GLN A 249
ASN A 218
GLY A 237
 None
 1.45A 3kmoA-3ljyA:
undetectable		 3kmoA-3ljyA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llq AQUAPORIN Z 2

(Agrobacterium
fabrum) 		PF00230
(MIP) 		5 PHE A  43
VAL A  47
GLY A 165
VAL A  16
GLN A 191
 None
 1.45A 3kmoA-3llqA:
undetectable		 3kmoA-3llqA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpd ACIDIC EXTRACELLULAR
SUBTILISIN-LIKE
PROTEASE APRV2

(Dichelobacter
nodosus) 		PF00082
(Peptidase_S8) 		5 TYR A  14
VAL A 126
GLY A 125
VAL A 330
GLY A 285
 None
 1.04A 3kmoA-3lpdA:
undetectable		 3kmoA-3lpdA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwk BETA-CRYSTALLIN A4

(Homo sapiens) 		PF00030
(Crystall) 		5 TYR A  74
VAL A  49
GLY A  72
VAL A  55
GLN A  66
 None
 1.27A 3kmoA-3lwkA:
undetectable		 3kmoA-3lwkA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwk BETA-CRYSTALLIN A4

(Homo sapiens) 		PF00030
(Crystall) 		5 TYR A 173
VAL A 144
GLY A 171
VAL A 150
GLN A 161
 None
None
None
GOL  A   2 (-4.5A)
GOL  A   2 (-3.6A)
 1.41A 3kmoA-3lwkA:
undetectable		 3kmoA-3lwkA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nro LMO1026 PROTEIN

(Listeria
monocytogenes) 		PF03816
(LytR_cpsA_psr) 		5 VAL A 248
GLY A 249
VAL A 167
ASN A 251
GLY A 162
 None
 1.31A 3kmoA-3nroA:
undetectable		 3kmoA-3nroA:
19.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		7 TYR A   7
PHE A   8
VAL A  10
GLY A  12
TRP A  38
ASN A 204
GLY A 205
 None
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
 0.32A 3kmoA-3o76A:
36.0		 3kmoA-3o76A:
84.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1

(Vibrio cholerae) 		PF01048
(PNP_UDP_1) 		5 VAL A 190
GLY A 188
VAL A 162
ASN A 166
GLY A 165
 None
 1.20A 3kmoA-3of3A:
undetectable		 3kmoA-3of3A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ono RIBOSE/GALACTOSE
ISOMERASE

(Vibrio
parahaemolyticus) 		PF02502
(LacAB_rpiB)
PF12408
(DUF3666) 		5 VAL A  88
GLY A  86
GLN A 150
ASN A 108
GLY A 107
 None
GOL  A 215 (-3.7A)
None
GOL  A 215 (-3.5A)
GOL  A 215 (-3.6A)
 1.17A 3kmoA-3onoA:
undetectable		 3kmoA-3onoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ono RIBOSE/GALACTOSE
ISOMERASE

(Vibrio
parahaemolyticus) 		PF02502
(LacAB_rpiB)
PF12408
(DUF3666) 		5 VAL A  88
GLY A  86
GLN A 151
ASN A 108
GLY A 107
 None
GOL  A 215 (-3.7A)
None
GOL  A 215 (-3.5A)
GOL  A 215 (-3.6A)
 1.38A 3kmoA-3onoA:
undetectable		 3kmoA-3onoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		5 VAL A  10
GLY A  42
GLN A 188
ASN A  41
GLY A   8
 None
 1.29A 3kmoA-3si9A:
undetectable		 3kmoA-3si9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti7 BASIC EXTRACELLULAR
SUBTILISIN-LIKE
PROTEASE BPRV

(Dichelobacter
nodosus) 		PF00082
(Peptidase_S8) 		5 TYR A  14
VAL A 126
GLY A 125
VAL A 330
GLY A 285
 None
 1.00A 3kmoA-3ti7A:
undetectable		 3kmoA-3ti7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vtf UDP-GLUCOSE
6-DEHYDROGENASE

(Pyrobaculum
islandicum) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		5 TYR A 237
GLY A 255
VAL A 234
ASN A 223
GLY A 226
 None
UPG  A1001 (-3.2A)
None
None
None
 1.33A 3kmoA-3vtfA:
undetectable		 3kmoA-3vtfA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvr PGM1

(Streptomyces
cirratus) 		no annotation 5 VAL A 154
GLY A 153
VAL A 327
GLN A 291
GLY A 298
 None
 1.29A 3kmoA-3wvrA:
undetectable		 3kmoA-3wvrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0m BETAINE ALDEHYDE
DEHYDROGENASE,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF00171
(Aldedh) 		5 GLY A 465
VAL A 452
GLN A 453
ASN A 475
GLY A 472
 None
 1.39A 3kmoA-4a0mA:
undetectable		 3kmoA-4a0mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b98 BETA-ALANINE--PYRUVA
TE TRANSAMINASE

(Pseudomonas
aeruginosa) 		PF00202
(Aminotran_3) 		5 TYR A 276
GLY A 381
VAL A 239
ASN A 379
GLY A 195
 None
None
PLP  A 501 ( 3.9A)
None
None
 1.31A 3kmoA-4b98A:
undetectable		 3kmoA-4b98A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0k A-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Chaetomium
thermophilum) 		no annotation 5 PHE A 288
VAL A 285
GLY A 300
VAL A 256
GLY A 261
 None
 1.38A 3kmoA-4d0kA:
undetectable		 3kmoA-4d0kA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		5 TYR A 244
VAL A 274
GLY A 242
VAL A 237
GLY A 159
 None
 1.31A 3kmoA-4ecnA:
undetectable		 3kmoA-4ecnA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcr GAMMA-B CRYSTALLIN

(Bos taurus) 		PF00030
(Crystall) 		5 TYR A 151
VAL A 126
GLY A 149
VAL A 132
GLN A 143
 None
 1.37A 3kmoA-4gcrA:
undetectable		 3kmoA-4gcrA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw8 BACTERIAL
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, PUTATIVE

(Staphylococcus
aureus) 		PF13416
(SBP_bac_8) 		5 PHE A 268
VAL A 265
GLY A 263
VAL A 269
ASN A 159
 None
 1.41A 3kmoA-4hw8A:
undetectable		 3kmoA-4hw8A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML

(Rhodospirillum
rubrum) 		PF03319
(EutN_CcmL) 		5 VAL A   6
GLY A  50
VAL A  42
ASN A  51
GLY A   8
 None
 1.27A 3kmoA-4i7aA:
undetectable		 3kmoA-4i7aA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgf GAMMA-CRYSTALLIN D

(Homo sapiens) 		PF00030
(Crystall) 		5 TYR A 150
VAL A 125
GLY A 148
VAL A 131
GLN A 142
 None
 1.34A 3kmoA-4jgfA:
undetectable		 3kmoA-4jgfA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mqd DNA-ENTRY NUCLEASE
INHIBITOR

(Bacillus
subtilis) 		PF11033
(ComJ) 		5 TYR A 106
VAL A  82
VAL A  19
ASN A  85
GLY A  86
 None
 1.39A 3kmoA-4mqdA:
undetectable		 3kmoA-4mqdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n02 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE

(Streptococcus
pneumoniae) 		PF01070
(FMN_dh) 		5 TYR A 168
VAL A 141
GLY A 119
VAL A 174
ASN A 117
 None
None
None
None
FNR  A 404 (-3.0A)
 1.30A 3kmoA-4n02A:
undetectable		 3kmoA-4n02A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Homo sapiens) 		PF00063
(Myosin_head)
PF01353
(GFP)
PF02736
(Myosin_N) 		5 TYR A 582
PHE A 465
GLY A 697
GLN A 475
GLY A 464
 None
 1.39A 3kmoA-4p7hA:
undetectable		 3kmoA-4p7hA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		5 VAL A1034
GLY A1044
VAL A1611
ASN A1553
GLY A1554
 None
 1.28A 3kmoA-4r04A:
undetectable		 3kmoA-4r04A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		5 VAL A2172
GLY A2170
GLN A2133
ASN A2174
GLY A2175
 None
 1.42A 3kmoA-4rh7A:
undetectable		 3kmoA-4rh7A:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkm MCCA

(Wolinella
succinogenes) 		no annotation 5 GLY A 219
VAL A  85
GLN A 234
ASN A 240
GLY A 238
 None
 1.45A 3kmoA-4rkmA:
undetectable		 3kmoA-4rkmA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892

(Streptococcus
agalactiae) 		PF02502
(LacAB_rpiB)
PF12408
(DUF3666) 		5 VAL A  89
GLY A  87
GLN A 152
ASN A 109
GLY A 108
 None
 1.42A 3kmoA-4u8fA:
undetectable		 3kmoA-4u8fA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w66 GLUTATHIONE
S-TRANSFERASE DOMAIN
PROTEIN

(Haliangium
ochraceum) 		PF14497
(GST_C_3) 		5 TYR A   9
PHE A  10
VAL A  12
GLY A  14
TRP A  40
 None
 0.35A 3kmoA-4w66A:
21.2		 3kmoA-4w66A:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd2 AROMATIC-AMINO-ACID
TRANSAMINASE TYRB

(Burkholderia
cenocepacia) 		PF00155
(Aminotran_1_2) 		5 PHE A 248
VAL A 255
GLY A 256
VAL A  49
GLY A 290
 None
 1.33A 3kmoA-4wd2A:
undetectable		 3kmoA-4wd2A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy4 SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 29
SYNTAXIN-17

(Homo sapiens) 		PF12352
(V-SNARE_C)
no annotation 		5 PHE B 189
VAL B 186
VAL B 193
GLN C  84
GLY C  74
 None
 1.27A 3kmoA-4wy4B:
undetectable		 3kmoA-4wy4B:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ys8 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Burkholderia
thailandensis) 		PF01128
(IspD) 		5 VAL A  54
GLY A  78
VAL A 106
ASN A  88
GLY A  89
 None
 1.20A 3kmoA-4ys8A:
undetectable		 3kmoA-4ys8A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5agt LEUCINE--TRNA LIGASE

(Mycobacterium
tuberculosis) 		PF13603
(tRNA-synt_1_2) 		5 TYR A 347
PHE A 426
VAL A 349
VAL A 408
TRP A 373
 None
 1.42A 3kmoA-5agtA:
undetectable		 3kmoA-5agtA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxm CYTOCHROME B6/F
COMPLEX IRON-SULFUR
SUBUNIT

(Synechocystis
sp. PCC 6803) 		PF00355
(Rieske) 		5 TYR A 120
VAL A  59
GLY A  57
ASN A  53
GLY A  52
 None
 1.36A 3kmoA-5cxmA:
undetectable		 3kmoA-5cxmA:
22.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
GLY A  12
TRP A  38
ASN A 203
GLY A 204
 None
GSH  A 301 (-4.9A)
None
GSH  A 301 (-4.0A)
None
None
 0.43A 3kmoA-5d73A:
30.5		 3kmoA-5d73A:
41.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1) 		PF12226
(Astro_capsid_p) 		5 TYR A 588
PHE A 582
VAL A 543
GLY A 586
GLY A 546
 None
 1.09A 3kmoA-5ewoA:
undetectable		 3kmoA-5ewoA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE

(Corynebacterium
glutamicum) 		PF01474
(DAHP_synth_2) 		5 TYR A 329
GLY A 297
VAL A 345
GLN A 374
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 1.27A 3kmoA-5hucA:
undetectable		 3kmoA-5hucA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5je8 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Bacillus cereus) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		5 TYR A 267
GLY A 180
VAL A 287
GLN A 290
GLY A 185
 None
 1.34A 3kmoA-5je8A:
undetectable		 3kmoA-5je8A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqn ALIPHATIC AMIDASE

(Nesterenkonia
sp. AN1) 		PF00795
(CN_hydrolase) 		5 VAL A  48
GLY A 204
VAL A  56
GLN A  60
GLY A  46
 None
 1.24A 3kmoA-5jqnA:
undetectable		 3kmoA-5jqnA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1c WD REPEAT-CONTAINING
PROTEIN 20

(Homo sapiens) 		PF00400
(WD40) 		5 TYR C  74
PHE C  67
VAL C  69
VAL C  50
GLY C 553
 None
 1.43A 3kmoA-5k1cC:
undetectable		 3kmoA-5k1cC:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngv ANTI-HUMAN ACTRIIB
MAB BYM338
LIGHT-CHAIN

(Homo sapiens) 		no annotation 5 VAL L  29
GLY L  30
VAL L 101
ASN L  71
GLY L  24
 None
 1.31A 3kmoA-5ngvL:
undetectable		 3kmoA-5ngvL:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szj RAS-RELATED PROTEIN
RAB-10

(Homo sapiens) 		PF00071
(Ras) 		5 VAL A  88
GLY A 121
GLN A  68
ASN A 122
GLY A  21
 None
None
None
GNP  A 301 (-3.2A)
GNP  A 301 (-3.0A)
 1.44A 3kmoA-5szjA:
undetectable		 3kmoA-5szjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3c CTP SYNTHASE

(Escherichia
coli) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		5 PHE A 529
VAL A 533
GLY A 531
ASN A 319
GLY A 316
 None
 1.40A 3kmoA-5u3cA:
undetectable		 3kmoA-5u3cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vh1 GAMMA S-CRYSTALLIN

(Gallus gallus) 		PF00030
(Crystall) 		5 TYR A 156
VAL A 131
GLY A 154
VAL A 137
GLN A 148
 None
 1.29A 3kmoA-5vh1A:
undetectable		 3kmoA-5vh1A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdr RAS PROTEIN

(Choanoflagellida) 		PF00071
(Ras) 		5 VAL A  81
GLY A 115
GLN A  61
ASN A 116
GLY A  15
 None
None
GNP  A 203 ( 4.5A)
GNP  A 203 (-3.2A)
GNP  A 203 (-2.9A)
 1.41A 3kmoA-5wdrA:
undetectable		 3kmoA-5wdrA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		5 TYR A1203
VAL A1251
VAL A1193
ASN A1199
GLY A1254
 None
 1.35A 3kmoA-5x7sA:
undetectable		 3kmoA-5x7sA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xcc PROBABLE SURFACE
PROTEIN

(Clostridium
perfringens) 		no annotation 5 TYR A 134
VAL A 157
GLY A 132
GLN A 125
GLY A  41
 None
 1.25A 3kmoA-5xccA:
undetectable		 3kmoA-5xccA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717

(Pseudoalteromonas
arctica) 		no annotation 5 TYR A 158
VAL A 265
GLY A 264
VAL A 473
GLY A 433
 None
 1.07A 3kmoA-5yl7A:
undetectable		 3kmoA-5yl7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bk1 UDP-GLYCOSYLTRANSFER
ASE 79

(Oryza sativa) 		no annotation 5 VAL A 375
GLY A 374
VAL A 284
GLN A 279
ASN A 373
 None
 1.29A 3kmoA-6bk1A:
undetectable		 3kmoA-6bk1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f72 MTVAO615

(Thermothelomyces
thermophila) 		no annotation 5 TYR A 532
PHE A 531
GLY A 281
VAL A 515
GLN A 503
 None
 1.41A 3kmoA-6f72A:
undetectable		 3kmoA-6f72A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f72 MTVAO615

(Thermothelomyces
thermophila) 		no annotation 5 TYR A 532
PHE A 531
GLY A 282
VAL A 515
GLN A 503
 None
 1.33A 3kmoA-6f72A:
undetectable		 3kmoA-6f72A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC
ATP SYNTHASE SUBUNIT
BETA, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 5 VAL D 176
GLY D 177
VAL C 364
GLN C 342
GLY D 173
 None
 1.42A 3kmoA-6fkhD:
undetectable		 3kmoA-6fkhD:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsa -

(-) 		no annotation 5 TYR A 582
PHE A 465
GLY A 697
GLN A 475
GLY A 464
 None
 1.33A 3kmoA-6fsaA:
undetectable		 3kmoA-6fsaA:
undetectable