SIMILAR PATTERNS OF AMINO ACIDS FOR 3KK6_A_CELA701_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aa2 BETA-SPECTRIN

(Homo sapiens) 		PF00307
(CH) 		4 VAL A  99
SER A  30
LEU A  54
LEU A  40
 None
 0.99A 3kk6A-1aa2A:
undetectable		 3kk6A-1aa2A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1axn ANNEXIN III

(Homo sapiens) 		PF00191
(Annexin) 		4 SER A 281
LEU A 263
ILE A 288
LEU A  84
 None
 0.86A 3kk6A-1axnA:
0.0		 3kk6A-1axnA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 HIS A1069
VAL A 879
SER A 854
LEU A 774
 None
 0.83A 3kk6A-1c30A:
0.0		 3kk6A-1c30A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8u ACYL-COA
THIOESTERASE II

(Escherichia
coli) 		PF13622
(4HBT_3) 		4 VAL A  57
LEU A   8
ILE A 182
LEU A  44
 None
 0.89A 3kk6A-1c8uA:
0.0		 3kk6A-1c8uA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cnv CONCANAVALIN B

(Canavalia
ensiformis) 		PF00704
(Glyco_hydro_18) 		4 HIS A 127
LEU A 101
ILE A 130
LEU A  48
 None
 0.99A 3kk6A-1cnvA:
0.0		 3kk6A-1cnvA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2n N-ETHYLMALEIMIDE-SEN
SITIVE FUSION
PROTEIN

(Cricetulus
griseus) 		PF00004
(AAA) 		4 VAL A 522
LEU A 649
ILE A 575
LEU A 526
 ANP  A   1 (-4.4A)
None
None
None
 0.99A 3kk6A-1d2nA:
undetectable		 3kk6A-1d2nA:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 HIS A  90
SER A 353
LEU A 507
ILE A 517
 None
 0.87A 3kk6A-1ebvA:
59.7		 3kk6A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		6 HIS A  90
VAL A 116
SER A 353
LEU A 384
ILE A 517
LEU A 531
 None
None
None
None
None
OAS  A 530 (-4.1A)
 0.45A 3kk6A-1ebvA:
59.7		 3kk6A-1ebvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16) 		4 VAL B 187
SER B 204
LEU B  67
LEU B  31
 None
 0.84A 3kk6A-1ezvB:
0.0		 3kk6A-1ezvB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gh6 RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A) 		4 HIS B 549
LEU B 486
ILE B 517
LEU B 389
 None
 0.95A 3kk6A-1gh6B:
undetectable		 3kk6A-1gh6B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnz GSI-B4 ISOLECTIN

(Griffonia
simplicifolia) 		PF00139
(Lectin_legB) 		4 HIS A 144
VAL A 186
ILE A 152
LEU A 184
 None
 0.66A 3kk6A-1gnzA:
undetectable		 3kk6A-1gnzA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gzc ERYTHRINA
CRISTA-GALLI LECTIN

(Erythrina
crista-galli) 		PF00139
(Lectin_legB) 		4 HIS A 142
VAL A 181
ILE A 150
LEU A 179
 MN  A 289 (-3.5A)
None
None
None
 0.81A 3kk6A-1gzcA:
undetectable		 3kk6A-1gzcA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5p PESTICIDIAL CRYSTAL
PROTEIN CRY2AA

(Bacillus
thuringiensis) 		PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
PF09131
(Endotoxin_mid) 		4 VAL A 269
SER A 260
LEU A 193
LEU A 267
 None
 0.82A 3kk6A-1i5pA:
0.0		 3kk6A-1i5pA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iyl MYRISTOYL-COA:PROTEI
N
N-MYRISTOYLTRANSFERA
SE

(Candida
albicans) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 VAL A 448
SER A 171
LEU A 128
LEU A 450
 None
 0.95A 3kk6A-1iylA:
undetectable		 3kk6A-1iylA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9o ALASERPIN

(Manduca sexta) 		PF00079
(Serpin) 		5 VAL I  92
SER I 104
LEU I  59
ILE I 106
LEU I  88
 None
 1.32A 3kk6A-1k9oI:
undetectable		 3kk6A-1k9oI:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1q ADENINE
PHOSPHORIBOSYLTRANSF
ERASE

(Giardia
intestinalis) 		PF00156
(Pribosyltran) 		4 HIS A  48
VAL A   5
SER A 176
ILE A 152
 None
 0.76A 3kk6A-1l1qA:
undetectable		 3kk6A-1l1qA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1q ADENINE
PHOSPHORIBOSYLTRANSF
ERASE

(Giardia
intestinalis) 		PF00156
(Pribosyltran) 		4 VAL A  41
LEU A 133
ILE A 158
LEU A  67
 None
 0.96A 3kk6A-1l1qA:
undetectable		 3kk6A-1l1qA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1led WEST-CENTRAL AFRICAN
LEGUME LECTIN IV

(Griffonia
simplicifolia) 		PF00139
(Lectin_legB) 		4 HIS A 145
VAL A 187
ILE A 153
LEU A 185
 MN  A 250 ( 3.4A)
None
None
None
 0.86A 3kk6A-1ledA:
undetectable		 3kk6A-1ledA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwd ISOCITRATE
DEHYDROGENASE

(Sus scrofa) 		PF00180
(Iso_dh) 		4 VAL A   7
LEU A 406
ILE A  27
LEU A 352
 None
 0.78A 3kk6A-1lwdA:
undetectable		 3kk6A-1lwdA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mf1 ADENYLOSUCCINATE
SYNTHETASE

(Mus musculus) 		PF00709
(Adenylsucc_synt) 		4 VAL A  50
SER A  96
LEU A 243
ILE A 129
 None
 0.99A 3kk6A-1mf1A:
undetectable		 3kk6A-1mf1A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n3p LECTIN PAL

(Pterocarpus
angolensis) 		PF00139
(Lectin_legB) 		4 HIS A 146
VAL A 185
ILE A 154
LEU A 183
 MN  A 271 (-3.5A)
None
None
None
 0.82A 3kk6A-1n3pA:
undetectable		 3kk6A-1n3pA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nav HORMONE RECEPTOR
ALPHA 1, THRA1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 VAL A 265
LEU A 236
ILE A 168
LEU A 261
 None
 0.94A 3kk6A-1navA:
undetectable		 3kk6A-1navA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5w AMINE OXIDASE
[FLAVIN-CONTAINING]
A

(Rattus
norvegicus) 		PF01593
(Amino_oxidase) 		5 VAL A  93
SER A 209
LEU A 176
ILE A 207
LEU A  97
 None
None
None
None
MLG  A 709 ( 4.9A)
 1.45A 3kk6A-1o5wA:
undetectable		 3kk6A-1o5wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofu CELL DIVISION
PROTEIN FTSZ
HYPOTHETICAL PROTEIN
PA3008

(Pseudomonas
aeruginosa) 		PF00091
(Tubulin)
PF03846
(SulA)
PF12327
(FtsZ_C) 		4 HIS X  89
VAL A 214
ILE A 299
LEU A 262
 None
 0.77A 3kk6A-1ofuX:
undetectable		 3kk6A-1ofuX:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A

(Homo sapiens) 		PF00076
(RRM_1)
PF02792
(Mago_nashi) 		4 HIS B 103
VAL A  56
LEU A  22
ILE A 143
 None
 0.89A 3kk6A-1p27B:
undetectable		 3kk6A-1p27B:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p3w CYSTEINE DESULFURASE

(Escherichia
coli) 		no annotation 4 VAL B 197
SER B 184
ILE B 207
LEU B 192
 None
 0.95A 3kk6A-1p3wB:
undetectable		 3kk6A-1p3wB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q4x THYROID HORMONE
RECEPTOR BETA-1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 VAL A 319
LEU A 290
ILE A 222
LEU A 315
 None
 0.93A 3kk6A-1q4xA:
0.8		 3kk6A-1q4xA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qmo MANNOSE BINDING
LECTIN, FRIL

(Lablab
purpureus) 		PF00139
(Lectin_legB) 		4 HIS E 154
VAL E 193
ILE E 162
LEU E 191
 MN  A 301 (-4.0A)
None
None
None
 0.80A 3kk6A-1qmoE:
undetectable		 3kk6A-1qmoE:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qot CHITIN BINDING
LECTIN, UEA-II

(Ulex europaeus) 		PF00139
(Lectin_legB) 		4 HIS A 144
VAL A 183
ILE A 152
LEU A 181
 MN  A 301 (-3.3A)
None
None
None
 0.83A 3kk6A-1qotA:
undetectable		 3kk6A-1qotA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r20 ULTRASPIRACLE
PROTEIN

(Heliothis
virescens) 		PF00104
(Hormone_recep) 		4 VAL A 441
SER A 428
LEU A 331
LEU A 230
 None
None
EPH  A4000 (-4.5A)
EPH  A4000 (-4.7A)
 0.98A 3kk6A-1r20A:
undetectable		 3kk6A-1r20A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rin PEA LECTIN

(Pisum sativum) 		PF00139
(Lectin_legB) 		4 HIS A 136
VAL A 175
ILE A 144
LEU A 173
 MN  A 240 (-3.5A)
None
None
None
 0.86A 3kk6A-1rinA:
undetectable		 3kk6A-1rinA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3i PROBABLE CYSTEINE
DESULFURASE

(Synechocystis
sp.) 		PF00266
(Aminotran_5) 		5 VAL A  30
SER A 405
LEU A 329
ILE A 410
LEU A  32
 None
 1.45A 3kk6A-1t3iA:
undetectable		 3kk6A-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdh NEI ENDONUCLEASE
VIII-LIKE 1

(Homo sapiens) 		PF01149
(Fapy_DNA_glyco)
PF06831
(H2TH)
PF09292
(Neil1-DNA_bind) 		4 VAL A 148
LEU A 288
ILE A 279
LEU A 198
 None
 0.92A 3kk6A-1tdhA:
undetectable		 3kk6A-1tdhA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzq EQUINATOXIN II

(Actinia equina) 		PF06369
(Anemone_cytotox) 		4 VAL A 102
LEU A  26
ILE A  18
LEU A  90
 None
 0.96A 3kk6A-1tzqA:
undetectable		 3kk6A-1tzqA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us8 DNA DOUBLE-STRAND
BREAK REPAIR RAD50
ATPASE

(Pyrococcus
furiosus) 		PF13476
(AAA_23) 		4 HIS A  14
SER A  37
LEU A   3
ILE A  28
 None
 0.85A 3kk6A-1us8A:
undetectable		 3kk6A-1us8A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uz5 402AA LONG
HYPOTHETICAL
MOLYBDOPTERIN
BIOSYNTHESIS MOEA
PROTEIN

(Pyrococcus
horikoshii) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 VAL A 251
LEU A   9
ILE A 329
LEU A 300
 None
 0.94A 3kk6A-1uz5A:
undetectable		 3kk6A-1uz5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vk5 EXPRESSED PROTEIN

(Arabidopsis
thaliana) 		PF09187
(RdDM_RDM1) 		4 HIS A 112
LEU A  90
ILE A  62
LEU A 122
 None
 0.91A 3kk6A-1vk5A:
undetectable		 3kk6A-1vk5A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqr HYPOTHETICAL PROTEIN
CJ0248

(Campylobacter
jejuni) 		PF08668
(HDOD) 		4 HIS A 188
VAL A  13
LEU A 114
LEU A  16
 None
 0.94A 3kk6A-1vqrA:
1.3		 3kk6A-1vqrA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdw TRYPTOPHAN SYNTHASE
BETA CHAIN 1

(Pyrococcus
furiosus) 		PF00291
(PALP) 		4 HIS B 332
LEU B 299
ILE B 380
LEU B 370
 None
 0.90A 3kk6A-1wdwB:
undetectable		 3kk6A-1wdwB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wra TEICHOIC ACID
PHOSPHORYLCHOLINE
ESTERASE/CHOLINE
BINDING PROTEIN E
(CBPE)

(Streptococcus
pneumoniae) 		PF00753
(Lactamase_B) 		4 HIS A  34
VAL A 275
SER A 326
LEU A 273
 None
 0.92A 3kk6A-1wraA:
undetectable		 3kk6A-1wraA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wta 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE

(Aeropyrum
pernix) 		PF01048
(PNP_UDP_1) 		4 VAL A  88
LEU A 197
ILE A  74
LEU A 209
 None
 0.95A 3kk6A-1wtaA:
undetectable		 3kk6A-1wtaA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xea OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Vibrio cholerae) 		PF01408
(GFO_IDH_MocA) 		4 HIS A  70
LEU A  60
ILE A   5
LEU A  84
 None
 0.96A 3kk6A-1xeaA:
undetectable		 3kk6A-1xeaA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9g EXO-INULINASE

(Aspergillus
awamori) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 327
SER A  75
LEU A 124
LEU A 321
 None
 0.99A 3kk6A-1y9gA:
undetectable		 3kk6A-1y9gA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb4 TARTRONIC
SEMIALDEHYDE
REDUCTASE

(Salmonella
enterica) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 HIS A  24
VAL A  28
LEU A 131
LEU A   8
 None
 0.99A 3kk6A-1yb4A:
undetectable		 3kk6A-1yb4A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z45 GAL10 BIFUNCTIONAL
PROTEIN

(Saccharomyces
cerevisiae) 		PF01263
(Aldose_epim)
PF16363
(GDP_Man_Dehyd) 		4 VAL A 637
SER A 538
ILE A 423
LEU A 635
 None
 0.96A 3kk6A-1z45A:
undetectable		 3kk6A-1z45A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl0 HYPOTHETICAL PROTEIN
PA5198

(Pseudomonas
aeruginosa) 		PF02016
(Peptidase_S66) 		4 VAL A  52
LEU A 158
ILE A  14
LEU A  32
 None
 0.87A 3kk6A-1zl0A:
undetectable		 3kk6A-1zl0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2d N-ACETYLGALACTOSAMIN
E KINASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg) 		4 VAL A 424
LEU A 144
ILE A  46
LEU A 443
 None
 0.82A 3kk6A-2a2dA:
0.2		 3kk6A-2a2dA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3b GLUCOSE-BINDING
PROTEIN

(Thermus
thermophilus) 		PF01547
(SBP_bac_1) 		4 VAL A 211
SER A 266
LEU A 131
LEU A 161
 None
 0.74A 3kk6A-2b3bA:
undetectable		 3kk6A-2b3bA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7y FAVIN BETA CHAIN

(Vicia faba) 		PF00139
(Lectin_legB) 		4 HIS A 137
VAL A 176
ILE A 145
LEU A 174
 MN  A 501 (-3.3A)
None
None
None
 0.88A 3kk6A-2b7yA:
undetectable		 3kk6A-2b7yA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bap DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		no annotation 4 VAL B 270
LEU B 293
ILE B 248
LEU B 312
 None
 0.98A 3kk6A-2bapB:
undetectable		 3kk6A-2bapB:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bib TEICHOIC ACID
PHOSPHORYLCHOLINE
ESTERASE/ CHOLINE
BINDING PROTEIN

(Streptococcus
pneumoniae) 		PF00753
(Lactamase_B)
PF01473
(CW_binding_1) 		4 HIS A   9
VAL A 250
SER A 301
LEU A 248
 None
 0.94A 3kk6A-2bibA:
undetectable		 3kk6A-2bibA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bqp PROTEIN (PEA LECTIN)

(Pisum sativum) 		PF00139
(Lectin_legB) 		4 HIS A 136
VAL A 175
ILE A 144
LEU A 173
 MN  A 236 (-3.7A)
None
None
None
 0.88A 3kk6A-2bqpA:
undetectable		 3kk6A-2bqpA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dua PHOSPHONOPYRUVATE
HYDROLASE

(Variovorax sp.
Pal2) 		PF13714
(PEP_mutase) 		5 HIS A  63
SER A  42
LEU A   7
ILE A  39
LEU A 184
 None
OXL  A 291 (-2.5A)
None
None
None
 1.21A 3kk6A-2duaA:
undetectable		 3kk6A-2duaA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1t ACYL TRANSFERASE

(Chrysanthemum x
morifolium) 		PF02458
(Transferase) 		4 VAL A 321
SER A 385
LEU A 297
ILE A 416
 MLC  A1001 ( 4.9A)
MLC  A1001 ( 4.0A)
None
None
 0.96A 3kk6A-2e1tA:
undetectable		 3kk6A-2e1tA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef0 ORNITHINE
CARBAMOYLTRANSFERASE

(Thermus
thermophilus) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 HIS A 134
VAL A 173
LEU A 299
LEU A  23
 None
 0.72A 3kk6A-2ef0A:
undetectable		 3kk6A-2ef0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eig LECTIN

(Lotus
tetragonolobus) 		PF00139
(Lectin_legB) 		4 HIS A 135
VAL A 174
ILE A 143
LEU A 172
 MN  A1101 (-3.4A)
None
None
None
 0.77A 3kk6A-2eigA:
undetectable		 3kk6A-2eigA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyn ALPHA-ACTININ 1

(Homo sapiens) 		PF00307
(CH) 		4 VAL A 242
SER A 172
LEU A 196
LEU A 182
 None
 0.89A 3kk6A-2eynA:
undetectable		 3kk6A-2eynA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmd LECTIN

(Leucomphalos
mildbraedii) 		PF00139
(Lectin_legB) 		4 HIS A 143
VAL A 182
ILE A 151
LEU A 180
 MN  A 302 (-3.6A)
None
None
None
 0.91A 3kk6A-2fmdA:
undetectable		 3kk6A-2fmdA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g2q GLUTAREDOXIN-2

(Vaccinia virus) 		PF05768
(DUF836) 		4 VAL A 102
LEU A  66
ILE A  37
LEU A  92
 None
 0.95A 3kk6A-2g2qA:
undetectable		 3kk6A-2g2qA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsn PHOSPHODIESTERASE-NU
CLEOTIDE
PYROPHOSPHATASE

(Xanthomonas
citri) 		PF01663
(Phosphodiest) 		4 HIS A  94
SER A 256
LEU A 180
ILE A  51
 None
 0.99A 3kk6A-2gsnA:
undetectable		 3kk6A-2gsnA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzs RNA POLYMERASE II
MEDIATOR COMPLEX
SUBUNIT 18
RNA POLYMERASE II
MEDIATOR COMPLEX
SUBUNIT 8

(Saccharomyces
cerevisiae) 		PF09637
(Med18)
no annotation 		4 VAL I 198
SER B   6
LEU B  23
LEU B 252
 None
 0.91A 3kk6A-2hzsI:
undetectable		 3kk6A-2hzsI:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE

(Arabidopsis
thaliana) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 SER A 460
LEU A 287
ILE A 300
LEU A 457
 None
 0.85A 3kk6A-2ix4A:
undetectable		 3kk6A-2ix4A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF01380
(SIS)
PF13522
(GATase_6) 		4 VAL A 536
LEU A 583
ILE A 478
LEU A 543
 None
 0.91A 3kk6A-2j6hA:
2.3		 3kk6A-2j6hA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k2n SENSOR PROTEIN

(Synechococcus
sp. RCC307) 		PF01590
(GAF) 		4 HIS A 159
VAL A 125
LEU A 181
LEU A 127
 None
 0.90A 3kk6A-2k2nA:
undetectable		 3kk6A-2k2nA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9n ACTIN-RELATED
PROTEIN 2/3 COMPLEX
SUBUNIT 1B

(Bos taurus) 		PF00400
(WD40) 		4 VAL C 359
SER C 257
LEU C 247
LEU C 285
 None
 0.90A 3kk6A-2p9nC:
undetectable		 3kk6A-2p9nC:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Agrobacterium
sp.) 		PF00275
(EPSP_synthase) 		4 SER A  34
LEU A  87
ILE A  79
LEU A 105
 None
 0.94A 3kk6A-2pqdA:
undetectable		 3kk6A-2pqdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rk0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
DOMAIN

(Frankia sp.
EAN1pec) 		PF00903
(Glyoxalase) 		4 VAL A   9
LEU A  89
ILE A 111
LEU A  51
 None
 0.99A 3kk6A-2rk0A:
undetectable		 3kk6A-2rk0A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4n MULTIFUNCTIONAL
PROTEIN SUR E

(Salmonella
enterica) 		PF01975
(SurE) 		5 VAL A 101
SER A 223
LEU A 150
ILE A 171
LEU A 227
 None
 1.33A 3kk6A-2v4nA:
undetectable		 3kk6A-2v4nA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9i RHAMNULOSE-1-PHOSPHA
TE ALDOLASE

(Escherichia
coli) 		PF00596
(Aldolase_II) 		4 VAL A 138
LEU A 108
ILE A   4
LEU A  33
 None
 0.89A 3kk6A-2v9iA:
undetectable		 3kk6A-2v9iA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3g TWO COMPONENT SENSOR
HISTIDINE KINASE
DEVS (GAF FAMILY
PROTEIN)

(Mycobacterium
tuberculosis) 		PF13185
(GAF_2) 		4 VAL A 200
LEU A 172
ILE A 121
LEU A  68
 None
 0.76A 3kk6A-2w3gA:
undetectable		 3kk6A-2w3gA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wae PENICILLIN-BINDING
PROTEIN 2B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 SER A 232
LEU A 276
ILE A 225
LEU A 495
 None
 0.96A 3kk6A-2waeA:
undetectable		 3kk6A-2waeA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpw ORF14

(Streptomyces
clavuligerus) 		PF00583
(Acetyltransf_1) 		4 HIS A 108
VAL A  92
LEU A  50
LEU A  27
 None
ACO  A 401 (-3.9A)
None
None
 0.94A 3kk6A-2wpwA:
undetectable		 3kk6A-2wpwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsk GLYCOGEN DEBRANCHING
ENZYME

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 VAL A 258
LEU A 538
ILE A 168
LEU A 198
 None
 0.97A 3kk6A-2wskA:
undetectable		 3kk6A-2wskA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xva TELLURITE RESISTANCE
PROTEIN TEHB

(Escherichia
coli) 		PF03848
(TehB) 		4 VAL A  22
LEU A  87
ILE A  65
LEU A 100
 None
SFG  A1198 (-3.8A)
None
None
 0.93A 3kk6A-2xvaA:
undetectable		 3kk6A-2xvaA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywd GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT

(Thermus
thermophilus) 		PF01174
(SNO) 		4 HIS A  36
VAL A  66
LEU A  21
LEU A  77
 None
 0.99A 3kk6A-2ywdA:
undetectable		 3kk6A-2ywdA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z02 PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Methanocaldococcus
jannaschii) 		PF01259
(SAICAR_synt) 		4 HIS A  75
VAL A 164
LEU A 241
LEU A 168
 ATP  A1527 (-4.1A)
None
None
None
 0.93A 3kk6A-2z02A:
undetectable		 3kk6A-2z02A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a21 PUTATIVE SECRETED
ALPHA-GALACTOSIDASE

(Streptomyces
avermitilis) 		PF00652
(Ricin_B_lectin)
PF16499
(Melibiase_2) 		4 VAL A 332
SER A 422
LEU A 388
ILE A 381
 None
None
None
GOL  A 915 (-4.7A)
 0.92A 3kk6A-3a21A:
undetectable		 3kk6A-3a21A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE

(Arthrobacter
sp. KI72) 		PF01425
(Amidase) 		4 VAL A 373
LEU A 419
ILE A 177
LEU A 303
 None
 0.96A 3kk6A-3a2qA:
undetectable		 3kk6A-3a2qA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3amj ZINC PEPTIDASE
INACTIVE SUBUNIT

(Sphingomonas
sp. A1) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 VAL B 421
SER B 314
LEU B 166
LEU B 426
 None
 0.98A 3kk6A-3amjB:
undetectable		 3kk6A-3amjB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emy TRICHODERMA REESEI
ASPARTIC PROTEASE

(Trichoderma
reesei) 		PF00026
(Asp) 		4 VAL A 174
SER A   1
ILE A  91
LEU A 311
 None
 0.93A 3kk6A-3emyA:
undetectable		 3kk6A-3emyA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fiu NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Francisella
tularensis) 		PF02540
(NAD_synthase) 		5 VAL A 174
SER A  47
LEU A 128
ILE A  83
LEU A 166
 None
 1.45A 3kk6A-3fiuA:
undetectable		 3kk6A-3fiuA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0m CYSTEINE
DESULFURATION
PROTEIN SUFE

(Salmonella
enterica) 		PF02657
(SufE) 		4 VAL A 102
LEU A  34
ILE A  77
LEU A  88
 None
None
EDO  A 202 (-3.9A)
None
 0.97A 3kk6A-3g0mA:
undetectable		 3kk6A-3g0mA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g77 CYTOSINE DEAMINASE

(Escherichia
coli) 		PF07969
(Amidohydro_3) 		5 HIS A 246
VAL A 298
LEU A 361
ILE A  62
LEU A 352
 FE  A 502 ( 4.8A)
None
None
None
None
 1.38A 3kk6A-3g77A:
undetectable		 3kk6A-3g77A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gde DNA LIGASE

(Archaeoglobus
fulgidus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 VAL A  76
SER A  83
LEU A 160
LEU A  98
 None
 0.95A 3kk6A-3gdeA:
undetectable		 3kk6A-3gdeA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h77 PQS BIOSYNTHETIC
ENZYME

(Pseudomonas
aeruginosa) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 HIS A  85
VAL A 141
LEU A  98
LEU A  54
 None
 0.82A 3kk6A-3h77A:
undetectable		 3kk6A-3h77A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf1 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		4 VAL A  69
LEU A  81
ILE A  92
LEU A  71
 None
 0.92A 3kk6A-3hf1A:
0.3		 3kk6A-3hf1A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if8 PROTEIN ZWILCH
HOMOLOG

(Homo sapiens) 		PF09817
(Zwilch) 		4 SER B 586
LEU A  55
ILE B 542
LEU A 151
 None
 0.94A 3kk6A-3if8B:
3.4		 3kk6A-3if8B:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0a TOLL-LIKE RECEPTOR 5

(Homo sapiens) 		PF01582
(TIR)
PF13855
(LRR_8) 		4 VAL A 362
LEU A 410
ILE A 372
LEU A 386
 None
 0.96A 3kk6A-3j0aA:
undetectable		 3kk6A-3j0aA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y MS30

(Homo sapiens) 		PF00829
(Ribosomal_L21p) 		4 HIS s 300
VAL s 181
LEU s 118
LEU s 425
 None
 0.81A 3kk6A-3j7ys:
undetectable		 3kk6A-3j7ys:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus) 		PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 VAL A 514
LEU A 641
ILE A 567
LEU A 518
 None
 0.72A 3kk6A-3j97A:
undetectable		 3kk6A-3j97A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jd5 28S RIBOSOMAL
PROTEIN S10,
MITOCHONDRIAL
28S RIBOSOMAL
PROTEIN S35,
MITOCHONDRIAL

(Bos taurus) 		PF00338
(Ribosomal_S10)
PF00411
(Ribosomal_S11) 		4 VAL k 196
LEU J 180
ILE k 153
LEU k 231
 None
 0.98A 3kk6A-3jd5k:
undetectable		 3kk6A-3jd5k:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1l FANCL

(Drosophila
melanogaster) 		no annotation 4 VAL B 166
SER B 217
LEU B 234
ILE B 215
 AU  B 385 (-3.9A)
None
None
None
 0.91A 3kk6A-3k1lB:
undetectable		 3kk6A-3k1lB:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd8 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Thermoplasma
acidophilum) 		PF01676
(Metalloenzyme)
PF10143
(PhosphMutase) 		4 HIS A  61
VAL A 387
LEU A  26
ILE A 295
 None
 0.98A 3kk6A-3kd8A:
undetectable		 3kk6A-3kd8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqe CAPSID PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 HIS A 270
VAL A 230
ILE A 420
LEU A 232
 None
 0.94A 3kk6A-3lqeA:
undetectable		 3kk6A-3lqeA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxd FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Novosphingobium
aromaticivorans) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 HIS A  19
VAL A  39
ILE A  67
LEU A  84
 FAD  A 416 (-4.3A)
None
None
None
 0.91A 3kk6A-3lxdA:
undetectable		 3kk6A-3lxdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtw L-ARGININE
CARBOXYPEPTIDASE
CC2672

(Caulobacter
vibrioides) 		PF01979
(Amidohydro_1) 		4 VAL A  51
LEU A 413
ILE A  87
LEU A  37
 None
 0.85A 3kk6A-3mtwA:
undetectable		 3kk6A-3mtwA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqk UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14274
(DUF4361)
PF16343
(DUF4973) 		4 VAL A 127
LEU A 172
ILE A  39
LEU A 129
 None
 0.97A 3kk6A-3nqkA:
undetectable		 3kk6A-3nqkA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nuu PKB-LIKE

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 345
LEU A 213
ILE A 271
LEU A 350
 None
None
None
GOL  A 365 (-3.9A)
 0.88A 3kk6A-3nuuA:
undetectable		 3kk6A-3nuuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olz GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		5 HIS A 225
VAL A 146
LEU A 231
ILE A 363
LEU A 157
 NAG  A 400 ( 4.7A)
None
None
None
None
 1.45A 3kk6A-3olzA:
0.2		 3kk6A-3olzA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omn CYTOCHROME C
OXIDASE, AA3 TYPE,
SUBUNIT I

(Rhodobacter
sphaeroides) 		PF00115
(COX1) 		5 HIS A 334
VAL A 245
LEU A 292
ILE A 355
LEU A 241
 CU1  A   5 (-3.1A)
None
None
None
None
 1.49A 3kk6A-3omnA:
undetectable		 3kk6A-3omnA:
20.89