SIMILAR PATTERNS OF AMINO ACIDS FOR 3K9W_A_ACTA170
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a40 | PHOSPHATE-BINDINGPERIPLASMIC PROTEINPRECURSOR (Escherichiacoli) |
PF12849(PBP_like_2) | 3 | SER A 139GLY A 140THR A 141 | PO4 A 322 ( 2.6A)PO4 A 322 ( 3.4A)PO4 A 322 ( 3.5A) | 0.10A | 3k9wA-1a40A:undetectable | 3k9wA-1a40A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dih | DIHYDRODIPICOLINATEREDUCTASE (Escherichiacoli) |
PF01113(DapB_N)PF05173(DapB_C) | 3 | SER A 168GLY A 169THR A 170 | None | 0.19A | 3k9wA-1dihA:3.8 | 3k9wA-1dihA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dyo | ENDO-1,4-BETA-XYLANASE Y (Ruminiclostridiumthermocellum) |
PF02018(CBM_4_9) | 3 | SER A 98GLY A 99THR A 100 | None | 0.19A | 3k9wA-1dyoA:undetectable | 3k9wA-1dyoA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eiz | FTSJ (Escherichiacoli) |
PF01728(FtsJ) | 3 | SER A 130GLY A 131THR A 132 | None | 0.24A | 3k9wA-1eizA:undetectable | 3k9wA-1eizA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f9a | HYPOTHETICAL PROTEINMJ0541 (Methanocaldococcusjannaschii) |
PF01467(CTP_transf_like) | 3 | SER A 125GLY A 126THR A 127 | ATP A 700 (-4.3A)ATP A 700 (-3.7A)ATP A 700 (-3.8A) | 0.20A | 3k9wA-1f9aA:16.4 | 3k9wA-1f9aA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7g | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Escherichiacoli) |
PF02348(CTP_transf_3) | 3 | SER A 75GLY A 76THR A 77 | None | 0.22A | 3k9wA-1h7gA:4.2 | 3k9wA-1h7gA:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyb | NICOTINAMIDEMONONUCLEOTIDEADENYLYLTRANSFERASE (Methanothermobacterthermautotrophicus) |
PF01467(CTP_transf_like) | 3 | SER A 131GLY A 132THR A 133 | SO4 A1759 ( 4.2A)SO4 A1759 (-3.1A)SO4 A1759 (-3.8A) | 0.22A | 3k9wA-1hybA:15.6 | 3k9wA-1hybA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2d | ATP SULFURYLASE (Penicilliumchrysogenum) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 358GLY A 359THR A 360 | None | 0.11A | 3k9wA-1i2dA:9.5 | 3k9wA-1i2dA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iug | PUTATIVE ASPARTATEAMINOTRANSFERASE (Thermusthermophilus) |
PF00266(Aminotran_5) | 3 | SER A 59GLY A 60THR A 61 | LLP A 185 ( 2.8A)LLP A 185 ( 3.7A)LLP A 185 ( 3.6A) | 0.21A | 3k9wA-1iugA:2.0 | 3k9wA-1iugA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j9l | STATIONARY PHASESURVIVAL PROTEIN (Thermotogamaritima) |
PF01975(SurE) | 3 | SER A 107GLY A 108THR A 109 | VO4 A 401 (-2.6A)VO4 A 401 (-3.9A)VO4 A 401 (-3.4A) | 0.09A | 3k9wA-1j9lA:3.2 | 3k9wA-1j9lA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jed | SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 357GLY A 358THR A 359 | None | 0.11A | 3k9wA-1jedA:9.8 | 3k9wA-1jedA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfx | 1,4-BETA-N-ACETYLMURAMIDASE M1 (Streptomycescoelicolor) |
PF01183(Glyco_hydro_25) | 3 | SER A 71GLY A 72THR A 73 | None | 0.12A | 3k9wA-1jfxA:undetectable | 3k9wA-1jfxA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jhd | SULFATEADENYLYLTRANSFERASE (Sulfur-oxidizingendosymbiont ofRiftiapachyptila) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 360GLY A 361THR A 362 | NoneSO4 A1002 (-3.6A)None | 0.17A | 3k9wA-1jhdA:9.1 | 3k9wA-1jhdA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kc8 | RIBOSOMAL PROTEINL18E (Haloarculamarismortui) |
PF00828(Ribosomal_L27A) | 3 | SER P 82GLY P 83THR P 84 | A A 660 ( 2.8A) A A 659 ( 3.9A) A A 660 ( 3.4A) | 0.19A | 3k9wA-1kc8P:undetectable | 3k9wA-1kc8P:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kpt | KP4 TOXIN (Ustilago maydis) |
PF09044(Kp4) | 3 | SER A 62GLY A 63THR A 64 | None | 0.12A | 3k9wA-1kptA:undetectable | 3k9wA-1kptA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5x | SURVIVAL PROTEIN E (Pyrobaculumaerophilum) |
PF01975(SurE) | 3 | SER A 106GLY A 107THR A 108 | None | 0.12A | 3k9wA-1l5xA:3.4 | 3k9wA-1l5xA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m6s | L-ALLO-THREONINEALDOLASE (Thermotogamaritima) |
PF01212(Beta_elim_lyase) | 3 | SER A 57GLY A 58THR A 59 | LLP A 199 ( 3.9A)LLP A 199 ( 3.3A)LLP A 199 ( 3.5A) | 0.16A | 3k9wA-1m6sA:undetectable | 3k9wA-1m6sA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oi7 | SUCCINYL-COASYNTHETASE ALPHACHAIN (Thermusthermophilus) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 3 | SER A 153GLY A 154THR A 155 | None | 0.15A | 3k9wA-1oi7A:3.2 | 3k9wA-1oi7A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6x | ATP:SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 357GLY A 358THR A 359 | None | 0.18A | 3k9wA-1r6xA:9.0 | 3k9wA-1r6xA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 3 | SER A 91GLY A 92THR A 93 | None | 0.16A | 3k9wA-1rf5A:undetectable | 3k9wA-1rf5A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rli | TRP REPRESSORBINDING PROTEIN (Bacillussubtilis) |
PF03358(FMN_red) | 3 | SER A 84GLY A 85THR A 86 | None | 0.17A | 3k9wA-1rliA:2.4 | 3k9wA-1rliA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1twy | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Vibrio cholerae) |
PF12727(PBP_like) | 3 | SER A 153GLY A 154THR A 155 | NonePO4 A1500 ( 3.7A)None | 0.10A | 3k9wA-1twyA:undetectable | 3k9wA-1twyA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcb | PROTEIN (ELONGIN C) (Homo sapiens) |
PF03931(Skp1_POZ) | 3 | SER B 39GLY B 40THR B 41 | None | 0.04A | 3k9wA-1vcbB:undetectable | 3k9wA-1vcbB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vef | ACETYLORNITHINE/ACETYL-LYSINEAMINOTRANSFERASE (Thermusthermophilus) |
PF00202(Aminotran_3) | 3 | SER A 112GLY A 113THR A 114 | PLP A 513 ( 4.0A)PLP A 513 (-3.2A)PLP A 513 (-3.8A) | 0.21A | 3k9wA-1vefA:undetectable | 3k9wA-1vefA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xnj | BIFUNCTIONAL3'-PHOSPHOADENOSINE5'-PHOSPHOSULFATESYNTHETASE 1 (Homo sapiens) |
no annotation | 3 | SER B 587GLY B 588THR B 589 | None | 0.22A | 3k9wA-1xnjB:9.6 | 3k9wA-1xnjB:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zj9 | PROBABLEFERREDOXIN-DEPENDENTNITRITE REDUCTASENIRA (Mycobacteriumtuberculosis) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 3 | SER A 354GLY A 355THR A 356 | None | 0.11A | 3k9wA-1zj9A:undetectable | 3k9wA-1zj9A:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cy8 | D-PHENYLGLYCINEAMINOTRANSFERASE (Pseudomonasstutzeri) |
PF00202(Aminotran_3) | 3 | SER A 121GLY A 122THR A 123 | None | 0.12A | 3k9wA-2cy8A:undetectable | 3k9wA-2cy8A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7u | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Thermusthermophilus) |
PF00202(Aminotran_3) | 3 | SER A 116GLY A 117THR A 118 | PMP A1001 (-3.7A)PMP A1001 (-3.5A)PMP A1001 (-3.6A) | 0.14A | 3k9wA-2e7uA:undetectable | 3k9wA-2e7uA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eh6 | ACETYLORNITHINEAMINOTRANSFERASE (Aquifexaeolicus) |
PF00202(Aminotran_3) | 3 | SER A 94GLY A 95THR A 96 | PLP A1001 (-3.9A)PLP A1001 (-3.3A)PLP A1001 (-3.5A) | 0.21A | 3k9wA-2eh6A:undetectable | 3k9wA-2eh6A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eo5 | 419AA LONGHYPOTHETICALAMINOTRANSFERASE (Sulfurisphaeratokodaii) |
PF00202(Aminotran_3) | 3 | SER A 112GLY A 113THR A 114 | PLP A1001 ( 3.8A)PLP A1001 ( 3.4A)PLP A1001 ( 3.8A) | 0.21A | 3k9wA-2eo5A:undetectable | 3k9wA-2eo5A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epj | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Aeropyrumpernix) |
PF00202(Aminotran_3) | 3 | SER A 120GLY A 121THR A 122 | PMP A 501 ( 3.8A)PMP A 501 ( 3.3A)PMP A 501 ( 3.5A) | 0.18A | 3k9wA-2epjA:undetectable | 3k9wA-2epjA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f7l | 455AA LONGHYPOTHETICALPHOSPHO-SUGAR MUTASE (Sulfurisphaeratokodaii) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 3 | SER A 423GLY A 424THR A 425 | SO4 A 460 (-3.5A)SO4 A 460 (-3.8A)SO4 A 460 (-4.1A) | 0.19A | 3k9wA-2f7lA:undetectable | 3k9wA-2f7lA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nzt | HEXOKINASE-2 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | SER A 122GLY A 123THR A 124 | None | 0.17A | 3k9wA-2nztA:undetectable | 3k9wA-2nztA:12.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pb0 | ACETYLORNITHINE/SUCCINYLDIAMINOPIMELATEAMINOTRANSFERASE (Salmonellaenterica) |
PF00202(Aminotran_3) | 3 | SER A 107GLY A 108THR A 109 | PLP A 555 (-3.6A)PLP A 555 (-3.3A)PLP A 555 ( 3.5A) | 0.15A | 3k9wA-2pb0A:undetectable | 3k9wA-2pb0A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9t | DING (Pseudomonasfluorescens) |
PF12849(PBP_like_2) | 3 | SER A 145GLY A 146THR A 147 | PO4 A 901 (-2.6A)PO4 A 901 (-3.6A)PO4 A 901 (-3.6A) | 0.07A | 3k9wA-2q9tA:undetectable | 3k9wA-2q9tA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qnl | UNCHARACTERIZEDPROTEIN (Cytophagahutchinsonii) |
PF12867(DinB_2) | 3 | SER A 45GLY A 46THR A 47 | None | 0.18A | 3k9wA-2qnlA:undetectable | 3k9wA-2qnlA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4n | MULTIFUNCTIONALPROTEIN SUR E (Salmonellaenterica) |
PF01975(SurE) | 3 | SER A 104GLY A 105THR A 106 | PO4 A1257 ( 3.9A)NoneNone | 0.21A | 3k9wA-2v4nA:2.5 | 3k9wA-2v4nA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vun | ENAMIDASE (Eubacteriumbarkeri) |
PF01979(Amidohydro_1) | 3 | SER A 279GLY A 280THR A 281 | None | 0.17A | 3k9wA-2vunA:undetectable | 3k9wA-2vunA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqk | 5'-NUCLEOTIDASE SURE (Aquifexaeolicus) |
PF01975(SurE) | 3 | SER A 106GLY A 107THR A 108 | SO4 A 252 (-2.8A)SO4 A 252 (-3.8A)SO4 A 252 (-3.7A) | 0.09A | 3k9wA-2wqkA:2.7 | 3k9wA-2wqkA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yky | BETA-TRANSAMINASE (Mesorhizobiumsp. LUK) |
PF00202(Aminotran_3) | 3 | SER A 144GLY A 145THR A 146 | PLP A1446 (-3.8A)PLP A1446 (-3.2A)PLP A1446 (-3.5A) | 0.23A | 3k9wA-2ykyA:undetectable | 3k9wA-2ykyA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z22 | PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Yersinia pestis) |
no annotation | 3 | SER X 139GLY X 140THR X 141 | PO4 X2322 (-2.5A)PO4 X2322 (-3.4A)PO4 X2322 (-3.6A) | 0.11A | 3k9wA-2z22X:undetectable | 3k9wA-2z22X:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bs8 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Bacillussubtilis) |
PF00202(Aminotran_3) | 3 | SER A 117GLY A 118THR A 119 | PMP A 431 ( 3.8A)PMP A 431 (-3.6A)PMP A 431 (-3.4A) | 0.15A | 3k9wA-3bs8A:undetectable | 3k9wA-3bs8A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cai | POSSIBLEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 3 | SER A 167GLY A 168THR A 169 | None | 0.18A | 3k9wA-3caiA:undetectable | 3k9wA-3caiA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd0 | PUTATIVECYSTATHIONINEBETA-LYASE INVOLVEDIN ALUMINUMRESISTANCE (Listeriainnocua) |
PF06838(Met_gamma_lyase) | 3 | SER A 84GLY A 85THR A 86 | LLP A 226 ( 3.3A)LLP A 226 ( 3.5A)LLP A 226 ( 3.6A) | 0.08A | 3k9wA-3fd0A:undetectable | 3k9wA-3fd0A:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fq8 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Synechococcuselongatus) |
PF00202(Aminotran_3) | 3 | SER A1122GLY A1123THR A1124 | PMP A5000 (-3.8A)PMP A5000 (-3.3A)PMP A5000 (-3.5A) | 0.12A | 3k9wA-3fq8A:undetectable | 3k9wA-3fq8A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg0 | KLEBSIELLAPNEUMONIAE BLRP1 (Klebsiellapneumoniae) |
PF00563(EAL)PF04940(BLUF) | 3 | SER A 335GLY A 336THR A 337 | None | 0.16A | 3k9wA-3gg0A:undetectable | 3k9wA-3gg0A:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gmi | UPF0348 PROTEINMJ0951 (Methanocaldococcusjannaschii) |
PF05636(HIGH_NTase1)PF16581(HIGH_NTase1_ass) | 3 | SER A 226GLY A 227THR A 228 | None | 0.12A | 3k9wA-3gmiA:11.7 | 3k9wA-3gmiA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i42 | RESPONSE REGULATORRECEIVER DOMAINPROTEIN (CHEY-LIKE) (Methylobacillusflagellatus) |
PF00072(Response_reg) | 3 | SER A 50GLY A 51THR A 52 | None | 0.20A | 3k9wA-3i42A:3.3 | 3k9wA-3i42A:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ijp | DIHYDRODIPICOLINATEREDUCTASE (Bartonellahenselae) |
PF01113(DapB_N)PF05173(DapB_C) | 3 | SER A 163GLY A 164THR A 165 | UNX A 271 ( 4.9A)UNX A 271 ( 3.7A)UNX A 270 ( 4.5A) | 0.16A | 3k9wA-3ijpA:3.6 | 3k9wA-3ijpA:28.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j31 | COAT PROTEIN (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 3 | SER A 79GLY A 80THR A 81 | None | 0.09A | 3k9wA-3j31A:undetectable | 3k9wA-3j31A:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jtj | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Yersinia pestis) |
PF02348(CTP_transf_3) | 3 | SER A 74GLY A 75THR A 76 | NoneNoneIMD A 301 (-4.3A) | 0.22A | 3k9wA-3jtjA:2.7 | 3k9wA-3jtjA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzl | PUTATIVECYSTATHIONINEBETA-LYASE INVOLVEDIN ALUMINUMRESISTANCE (Listeriamonocytogenes) |
PF06838(Met_gamma_lyase) | 3 | SER A 84GLY A 85THR A 86 | LLP A 226 ( 3.3A)LLP A 226 ( 3.5A)LLP A 226 ( 3.4A) | 0.03A | 3k9wA-3jzlA:undetectable | 3k9wA-3jzlA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k28 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE2 (Bacillusanthracis) |
PF00202(Aminotran_3) | 3 | SER A 117GLY A 118THR A 119 | PLP A 900 (-4.0A)PLP A 900 (-3.3A)PLP A 900 (-3.7A) | 0.14A | 3k9wA-3k28A:undetectable | 3k9wA-3k28A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ke3 | PUTATIVESERINE-PYRUVATEAMINOTRANSFERASE (Psychrobacterarcticus) |
PF00266(Aminotran_5) | 3 | SER A 58GLY A 59THR A 60 | LLP A 198 ( 2.9A)LLP A 198 ( 3.6A)LLP A 198 ( 3.6A) | 0.21A | 3k9wA-3ke3A:undetectable | 3k9wA-3ke3A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l44 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE1 (Bacillusanthracis) |
PF00202(Aminotran_3) | 3 | SER A 119GLY A 120THR A 121 | LLP A 270 ( 3.9A)LLP A 270 ( 3.2A)LLP A 270 ( 3.5A) | 0.17A | 3k9wA-3l44A:undetectable | 3k9wA-3l44A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lr1 | TUNGSTATE ABCTRANSPORTER,PERIPLASMICTUNGSTATE-BINDINGPROTEIN (Geobactersulfurreducens) |
PF12849(PBP_like_2) | 3 | SER A 122GLY A 123THR A 124 | W A 234 ( 4.7A)NoneNone | 0.18A | 3k9wA-3lr1A:undetectable | 3k9wA-3lr1A:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m8y | PHOSPHOPENTOMUTASE (Bacillus cereus) |
PF01676(Metalloenzyme) | 3 | SER A 131GLY A 132THR A 133 | None | 0.12A | 3k9wA-3m8yA:undetectable | 3k9wA-3m8yA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mnz | ANTI-HIV-1 ANTIBODY13H11 LIGHT CHAIN (Homo sapiens;Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | SER A 127GLY A 128THR A 129 | None | 0.17A | 3k9wA-3mnzA:undetectable | 3k9wA-3mnzA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muq | UNCHARACTERIZEDCONSERVED PROTEIN (Vibrioparahaemolyticus) |
PF12849(PBP_like_2) | 3 | SER A 147GLY A 148THR A 149 | None | 0.19A | 3k9wA-3muqA:undetectable | 3k9wA-3muqA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mvg | RIBOSOMEINACTIVATING TYPE 1PROTEIN (Iris xhollandica) |
PF00161(RIP) | 3 | SER A 29GLY A 30THR A 31 | SO4 A 276 ( 4.8A)GOL A 277 ( 3.7A)None | 0.23A | 3k9wA-3mvgA:undetectable | 3k9wA-3mvgA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nx3 | ACETYLORNITHINEAMINOTRANSFERASE (Campylobacterjejuni) |
PF00202(Aminotran_3) | 3 | SER A 101GLY A 102THR A 103 | None | 0.19A | 3k9wA-3nx3A:undetectable | 3k9wA-3nx3A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o2k | BREVIANAMIDE FPRENYLTRANSFERASE (Aspergillusfumigatus) |
PF11991(Trp_DMAT) | 3 | SER A 195GLY A 196THR A 197 | None | 0.23A | 3k9wA-3o2kA:undetectable | 3k9wA-3o2kA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oam | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Vibrio cholerae) |
PF02348(CTP_transf_3) | 3 | SER A 74GLY A 75THR A 76 | None | 0.24A | 3k9wA-3oamA:3.9 | 3k9wA-3oamA:22.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3pxu | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Burkholderiapseudomallei) |
PF01467(CTP_transf_like) | 3 | SER A 127GLY A 128THR A 129 | SO4 A 205 (-3.0A)SO4 A 205 (-3.8A)SO4 A 205 (-4.3A) | 0.05A | 3k9wA-3pxuA:30.8 | 3k9wA-3pxuA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qy9 | DIHYDRODIPICOLINATEREDUCTASE (Staphylococcusaureus) |
PF01113(DapB_N)PF05173(DapB_C) | 3 | SER A 144GLY A 145THR A 146 | SO4 A 242 (-3.7A)SO4 A 242 (-3.6A)SO4 A 242 (-3.9A) | 0.22A | 3k9wA-3qy9A:2.2 | 3k9wA-3qy9A:25.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rmt | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE 1 (Bacillushalodurans) |
PF00275(EPSP_synthase) | 3 | SER A 96GLY A 97THR A 98 | SO4 A 500 ( 4.0A)SO4 A 500 (-3.4A)SO4 A 507 (-3.6A) | 0.17A | 3k9wA-3rmtA:undetectable | 3k9wA-3rmtA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpi | LIGHT CHAIN FROMHIGHLY POTENTANTI-HIVNEUTRALIZINGANTIBODY (Homo sapiens) |
no annotation | 3 | SER L 116GLY L 117THR L 118 | None | 0.24A | 3k9wA-3rpiL:undetectable | 3k9wA-3rpiL:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty2 | 5'-NUCLEOTIDASE SURE (Coxiellaburnetii) |
PF01975(SurE) | 3 | SER A 114GLY A 115THR A 116 | None | 0.08A | 3k9wA-3ty2A:3.2 | 3k9wA-3ty2A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9v | PHOSPHATE-BINDINGPROTEIN (unidentifiedprokaryoticorganism) |
PF12849(PBP_like_2) | 3 | SER A 144GLY A 145THR A 146 | PO4 A 401 (-2.7A)PO4 A 401 (-3.6A)PO4 A 401 (-3.6A) | 0.09A | 3k9wA-3w9vA:undetectable | 3k9wA-3w9vA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wgc | L-ALLO-THREONINEALDOLASE (Aeromonasjandaei) |
PF01212(Beta_elim_lyase) | 3 | SER A 59GLY A 60THR A 61 | PLG A 401 (-3.6A)PLG A 401 (-3.2A)PLG A 401 (-3.8A) | 0.19A | 3k9wA-3wgcA:undetectable | 3k9wA-3wgcA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqb | OPEN READING FRAME 2 (Aeromonassobria) |
no annotation | 3 | SER B 63GLY B 64THR B 65 | None | 0.20A | 3k9wA-3wqbB:undetectable | 3k9wA-3wqbB:25.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aoa | BETA-PHENYLALANINEAMINOTRANSFERASE (Variovoraxparadoxus) |
PF00202(Aminotran_3) | 3 | SER A 131GLY A 132THR A 133 | IK2 A1435 (-3.8A)IK2 A1435 (-3.4A)IK2 A1435 (-3.6A) | 0.15A | 3k9wA-4aoaA:undetectable | 3k9wA-4aoaA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dnx | SULFATEADENYLYLTRANSFERASE (Allochromatiumvinosum) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 360GLY A 361THR A 362 | None | 0.17A | 3k9wA-4dnxA:9.0 | 3k9wA-4dnxA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e77 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Yersinia pestis) |
PF00202(Aminotran_3) | 3 | SER A 114GLY A 115THR A 116 | NO3 A 502 (-4.7A)NO3 A 502 (-3.5A)None | 0.04A | 3k9wA-4e77A:undetectable | 3k9wA-4e77A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecf | ABC-TYPE PHOSPHATETRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Lactobacillusbrevis) |
PF12849(PBP_like_2) | 3 | SER A 160GLY A 161THR A 162 | PO4 A 300 (-2.6A)PO4 A 300 (-3.6A)PO4 A 300 (-3.5A) | 0.06A | 3k9wA-4ecfA:undetectable | 3k9wA-4ecfA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fcu | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Acinetobacterbaumannii) |
PF02348(CTP_transf_3) | 3 | SER A 74GLY A 75THR A 76 | None | 0.09A | 3k9wA-4fcuA:2.7 | 3k9wA-4fcuA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g6a | AP33 LIGHT CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | SER D 127GLY D 128THR D 129 | None | 0.19A | 3k9wA-4g6aD:undetectable | 3k9wA-4g6aD:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gd5 | PHOSPHATE ABCTRANSPORTER,PHOSPHATE-BINDINGPROTEIN (Clostridiumperfringens) |
PF12849(PBP_like_2) | 3 | SER A 159GLY A 160THR A 161 | PO4 A 301 (-2.7A)PO4 A 301 (-3.5A)PO4 A 301 (-3.6A) | 0.08A | 3k9wA-4gd5A:undetectable | 3k9wA-4gd5A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h1x | PHOSPHATE-BINDINGPROTEIN PSTS 2 (Streptococcuspneumoniae) |
PF12849(PBP_like_2) | 3 | SER A 46GLY A 47THR A 48 | CIT A 302 (-2.5A)CIT A 302 (-3.2A)CIT A 302 (-3.3A) | 0.08A | 3k9wA-4h1xA:undetectable | 3k9wA-4h1xA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjj | ANTI-IL12 ANTI-IL18DFAB LIGHT CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | SER L 241GLY L 242THR L 243 | None | 0.20A | 3k9wA-4hjjL:undetectable | 3k9wA-4hjjL:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwg | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Rickettsiabellii) |
PF02350(Epimerase_2) | 3 | SER A 282GLY A 283THR A 284 | None | 0.24A | 3k9wA-4hwgA:4.2 | 3k9wA-4hwgA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixo | NIFS-LIKE PROTEIN (Rickettsiaafricae) |
PF00266(Aminotran_5) | 3 | SER A 71GLY A 72THR A 73 | LLP A 196 ( 3.8A)LLP A 196 ( 3.5A)LLP A 196 ( 3.6A) | 0.18A | 3k9wA-4ixoA:undetectable | 3k9wA-4ixoA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwo | PHOSPHATE BINDINGPROTEIN (Planctopiruslimnophila) |
PF12727(PBP_like) | 3 | SER A 194GLY A 195THR A 196 | None | 0.19A | 3k9wA-4jwoA:undetectable | 3k9wA-4jwoA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2b | NTD BIOSYNTHESISOPERON PROTEIN NTDA (Bacillussubtilis) |
PF01041(DegT_DnrJ_EryC1) | 3 | SER A 124GLY A 125THR A 126 | LLP A 247 ( 3.7A)LLP A 247 ( 3.2A)LLP A 247 ( 3.6A) | 0.14A | 3k9wA-4k2bA:undetectable | 3k9wA-4k2bA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lc3 | PUTATIVEUDP-4-AMINO-4-DEOXY-L-ARABINOSE--OXOGLUTARATEAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01041(DegT_DnrJ_EryC1) | 3 | SER A 60GLY A 61THR A 62 | CIT A 401 (-3.8A)CIT A 401 (-3.5A)CIT A 401 ( 3.7A) | 0.22A | 3k9wA-4lc3A:undetectable | 3k9wA-4lc3A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvq | PHOSPHATE-BINDINGPROTEIN PSTS 3 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 3 | SER A 191GLY A 192THR A 193 | PO4 A 401 (-2.6A)PO4 A 401 (-3.4A)PO4 A 401 (-4.2A) | 0.13A | 3k9wA-4lvqA:undetectable | 3k9wA-4lvqA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4maf | ATP SULFURYLASE (Glycine max) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | SER A 414GLY A 415THR A 416 | None | 0.09A | 3k9wA-4mafA:9.7 | 3k9wA-4mafA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n7t | PHOSPHOPENTOMUTASE (Streptococcusmutans) |
PF01676(Metalloenzyme) | 3 | SER A 140GLY A 141THR A 142 | NoneSO4 A 503 (-3.2A)None | 0.20A | 3k9wA-4n7tA:undetectable | 3k9wA-4n7tA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4omb | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 3 | SER A 185GLY A 186THR A 187 | PO4 A 401 (-2.5A)PO4 A 401 (-3.4A)PO4 A 401 (-3.5A) | 0.12A | 3k9wA-4ombA:undetectable | 3k9wA-4ombA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pqj | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 3 | SER A 185GLY A 186THR A 187 | PO4 A 401 (-2.6A)PO4 A 401 (-3.4A)PO4 A 401 (-3.5A) | 0.14A | 3k9wA-4pqjA:undetectable | 3k9wA-4pqjA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q8r | PHOSPHATE ABCTRANSPORTER,PHOSPHATE-BINDINGPROTEIN (Clostridiumperfringens) |
PF12849(PBP_like_2) | 3 | SER A 129GLY A 130THR A 131 | PO4 A 301 (-2.6A)PO4 A 301 (-3.5A)PO4 A 301 (-3.6A) | 0.07A | 3k9wA-4q8rA:undetectable | 3k9wA-4q8rA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r72 | ABC-TYPE FE3+TRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Actinobacilluspleuropneumoniae) |
PF13343(SBP_bac_6) | 3 | SER A 148GLY A 149THR A 150 | GOL A 402 (-2.5A)GOL A 402 (-4.0A)GOL A 402 (-3.7A) | 0.11A | 3k9wA-4r72A:undetectable | 3k9wA-4r72A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8j | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 3 | SER A 593GLY A 594THR A 595 | None | 0.17A | 3k9wA-4w8jA:undetectable | 3k9wA-4w8jA:9.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwi | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Pseudomonasaeruginosa) |
PF02348(CTP_transf_3) | 3 | SER A 76GLY A 77THR A 78 | None | 0.21A | 3k9wA-4xwiA:3.3 | 3k9wA-4xwiA:25.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ydk | LIGHT CHAIN OFANTIBODYC38-VRC16.01 (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | SER L 127GLY L 128THR L 129 | None | 0.24A | 3k9wA-4ydkL:undetectable | 3k9wA-4ydkL:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywj | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Pseudomonasaeruginosa) |
PF01113(DapB_N)PF05173(DapB_C) | 3 | SER A 165GLY A 166THR A 167 | None | 0.12A | 3k9wA-4ywjA:3.2 | 3k9wA-4ywjA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg5 | 5'-NUCLEOTIDASE SURE (Brucellaabortus) |
no annotation | 3 | SER D 104GLY D 105THR D 106 | None | 0.11A | 3k9wA-4zg5D:2.9 | 3k9wA-4zg5D:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zm4 | AMINOTRANSFERASE (Streptomycespactum) |
PF00202(Aminotran_3) | 3 | SER A 119GLY A 120THR A 121 | PLP A 501 (-4.1A)PLP A 501 (-3.2A)PLP A 501 (-3.4A) | 0.21A | 3k9wA-4zm4A:undetectable | 3k9wA-4zm4A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwv | PUTATIVEAMINOTRANSFERASE (Actinomaduramelliaura) |
PF01041(DegT_DnrJ_EryC1) | 3 | SER A 53GLY A 54THR A 55 | LLP A 187 ( 3.7A)LLP A 187 ( 3.4A)LLP A 187 ( 3.6A) | 0.16A | 3k9wA-4zwvA:undetectable | 3k9wA-4zwvA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a05 | ALDOSE-ALDOSEOXIDOREDUCTASE (Caulobactervibrioides) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | SER A 39GLY A 40THR A 41 | NDP A1340 (-2.5A)NDP A1340 (-3.5A)NDP A1340 (-3.6A) | 0.23A | 3k9wA-5a05A:2.5 | 3k9wA-5a05A:24.54 |